Page last updated: 2024-08-22

n-methylaspartate and Chronic Disease

n-methylaspartate has been researched along with Chronic Disease in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (28.57)18.2507
2000's9 (32.14)29.6817
2010's9 (32.14)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Huang, ST; Li, H; Li, NQ; Liu, XT; Tang, Y; Wan, L; Zeng, LP1
Bennett, DJ; Birch, D; Heckman, CJ; Jiang, MC; Thaweerattanasinp, T; Tresch, MC; Tysseling, VM1
Cevik, OS; Kocahan, S; Koyuncu, DD; Sahin, L1
Alberch, J; Ceña, V; Collon, KW; Domercq, M; Fernández-Díez, B; Franco, R; Giralt, A; Giralt, E; Gottlieb, M; Lopez, I; Martínez-Pinilla, E; Matute, C; Moreno, B; Parent, JM; Posadas, I; Sánchez-Gómez, MV; Teixido, M; Villoslada, P; Zhang, H1
Cheon, Y; Igarashi, M; Keleshian, VL; Kellom, M; Kim, HW; Rao, JS; Rapoport, SI; Taha, AY1
Chang, JC; Chang, WP; Chen, IM; Cheng, JK; Chiu, HF; Lin, CH; Lin, CI; Lin, PH1
Ma, LQ; Peng, YZ; Shen, FY; Wang, B; Wang, ZR; Wen, W; Zhang, TT; Zhao, X1
Cunningham, CJ; Liu, X; Patel, KP; Sharma, NM; Zheng, H1
McNulty, JP1
Patel, KP; Xu, B; Zheng, H1
Plunkett, AR; Turabi, A1
Caspary, DM; Llano, DA; Turner, J1
Chen, JG; Guan, BC; Li, ZW; Liu, CJ; Wu, ZZ; Yang, Q1
Hemby, SE; Joëls, M; Verkuyl, JM1
Andreasson, K; Breyer, R; Liu, D; Mattson, MP; Wu, L1
Erceg, S; Felipo, V; Piedrafita, B; Rodrigo, R; Rodriguez-Diaz, J; Saez-Valero, J; Suarez, I1
Cremaschi, GA; Fosser, NS; Genaro, AM; Guelman, LR; Palumbo, ML; Rios, H; Zorrilla Zubilete, MA1
Cai, Z; Hersey, K; Rhodes, PG; Sigrest, T1
Chen, Q; Leahy, JC; Vallano, ML1
Birch, PJ; Elliott, PJ; Harrison, SM; Smith, GD; Wiseman, J1
Murray, M; Nag, S; Riopelle, RJ; Zochodne, DW1
Klenk-Majewska, B; Ossowska, G; Szymczyk, G1
Eisenach, J1
Katsumori, H; Liu, H; Mazarati, AM; Penix, L; Shirasaka, Y; Thompson, KW; Wasterlain, CG1
Feuerstein, TJ; Fischer, W; Kiefer, G1
Dobrogowski, J; Wordliczek, J1
Bernardi, G; Calabresi, P; Centonze, D; Gubellini, P1
Castro, GD; Castro, JA; de Layño, AM; Fanelli, SL; Gómez, MI; Valles, E1

Reviews

3 review(s) available for n-methylaspartate and Chronic Disease

ArticleYear
The application of genomic and molecular data in the treatment of chronic cancer pain.
    Journal of surgical oncology, 2012, Apr-01, Volume: 105, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents; Antineoplastic Agents; Autonomic Nerve Block; Catechol O-Methyltransferase; Chronic Disease; Genetic Therapy; Humans; N-Methylaspartate; Neoplasms; Pain; Pain Management; Polymorphism, Single Nucleotide; Receptors, Opioid, mu; Somatosensory Cortex; Translational Research, Biomedical

2012
Update on spinal cord pharmacology in pain.
    Acta anaesthesiologica Scandinavica. Supplementum, 1997, Volume: 110

    Topics: Acute Disease; Adrenergic alpha-Agonists; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell- and Tissue-Based Therapy; Cholinesterase Inhibitors; Chromaffin Cells; Chronic Disease; Delayed-Action Preparations; Humans; Muscarinic Agonists; N-Methylaspartate; Nerve Fibers; Neurotransmitter Agents; Nitric Oxide Synthase; Nociceptors; Norepinephrine; Pain; Rats; Receptors, Adrenergic, alpha; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Tachykinin; Spinal Cord

1997
[Pathophysiology of postoperative pain].
    Przeglad lekarski, 2000, Volume: 57, Issue:4

    Topics: Chronic Disease; Humans; N-Methylaspartate; Nociceptors; Pain, Postoperative; Receptors, Muscarinic; Receptors, Nicotinic; Receptors, Opioid; Wound Healing

2000

Other Studies

25 other study(ies) available for n-methylaspartate and Chronic Disease

ArticleYear
Modulation of NR1 receptor by CaMKIIα plays an important role in chronic itch development in mice.
    Brain research bulletin, 2020, Volume: 158

    Topics: Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Chronic Disease; Dinitrofluorobenzene; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nerve Tissue Proteins; Protein Kinase Inhibitors; Pruritus; Receptors, N-Methyl-D-Aspartate; Sulfonamides

2020
Bursting interneurons in the deep dorsal horn develop increased excitability and sensitivity to serotonin after chronic spinal injury.
    Journal of neurophysiology, 2020, 05-01, Volume: 123, Issue:5

    Topics: Action Potentials; Animals; Chronic Disease; Disease Models, Animal; Excitatory Postsynaptic Potentials; Interneurons; Mice; Mice, Inbred C57BL; Motor Neurons; N-Methylaspartate; Oxazolidinones; Posterior Horn Cells; Serotonin; Serotonin 5-HT1 Receptor Agonists; Spasm; Spinal Cord Injuries; Spinal Nerve Roots; Tryptamines

2020
Caffeine as a potential arousal enhancer: altered NMDA subunit gene expression without improving cognitive performance in REM sleep deprived rats.
    Cellular and molecular biology (Noisy-le-Grand, France), 2019, Feb-28, Volume: 65, Issue:2

    Topics: Animals; Arousal; Caffeine; Chronic Disease; Cognition; Gene Expression Regulation; Maze Learning; Memory; N-Methylaspartate; Protein Subunits; Rats, Wistar; Sleep Deprivation; Spatial Learning

2019
Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Acute Disease; Adrenergic Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood-Brain Barrier; Brain Ischemia; Cell Membrane Permeability; Cells, Cultured; Chronic Disease; Deoxyadenosines; Disease Models, Animal; Glucose; Male; Mice; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Oxygen; Pilocarpine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Status Epilepticus; Thionucleosides

2014
Neuropathological responses to chronic NMDA in rats are worsened by dietary n-3 PUFA deprivation but are not ameliorated by fish oil supplementation.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Animals; Brain Chemistry; Brain Diseases; Chronic Disease; Dietary Fats; Excitatory Amino Acid Agonists; Fatty Acids, Omega-3; Group IV Phospholipases A2; Interleukin-1beta; Lipid Metabolism; Male; N-Methylaspartate; Nerve Growth Factor; Rats

2014
A mechanistic study on urine retention in d-amphetamine addicts.
    The Chinese journal of physiology, 2014, Aug-31, Volume: 57, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Amidines; Amphetamine-Related Disorders; Animals; Benzophenanthridines; Central Nervous System Stimulants; Chronic Disease; Colforsin; Dextroamphetamine; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Isoquinolines; N-Methylaspartate; Oxidants; Protein Kinase Inhibitors; Rats, Wistar; Reflex; Spinal Cord; Sulfonamides; Urinary Retention; Urination; Valine

2014
Potentiation of synaptic transmission in Rat anterior cingulate cortex by chronic itch.
    Molecular brain, 2016, 07-29, Volume: 9, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Chronic Disease; Cyclopropanes; Disease Models, Animal; Excitatory Postsynaptic Potentials; Gyrus Cinguli; N-Methylaspartate; Neurons; Pruritus; Rats, Sprague-Dawley; Receptors, AMPA; Synaptic Transmission; Up-Regulation

2016
Hypoxia-Inducible Factor-1α Mediates Increased Sympathoexcitation via Glutamatergic N-Methyl-d-Aspartate Receptors in the Paraventricular Nucleus of Rats With Chronic Heart Failure.
    Circulation. Heart failure, 2016, Volume: 9, Issue:11

    Topics: Animals; Cell Line; Chromatin Immunoprecipitation; Chronic Disease; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Agonists; Heart Failure; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sympathetic Nervous System; Up-Regulation

2016
Chronic pain: levorphanol, methadone, and the N-methyl-D-aspartate receptor.
    Journal of palliative medicine, 2009, Volume: 12, Issue:9

    Topics: Analgesics, Opioid; Chronic Disease; Hospice Care; Humans; Levorphanol; Methadone; N-Methylaspartate; Narcotics; Pain; Palliative Care; Receptors, N-Methyl-D-Aspartate

2009
Enhanced activation of RVLM-projecting PVN neurons in rats with chronic heart failure.
    American journal of physiology. Heart and circulatory physiology, 2012, Apr-15, Volume: 302, Issue:8

    Topics: 2-Amino-5-phosphonovalerate; Animals; Chronic Disease; Coronary Vessels; Electric Stimulation; Electrophysiological Phenomena; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Heart Failure; Ligation; Male; Medulla Oblongata; Midline Thalamic Nuclei; N-Methylaspartate; Neurons; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Osmolar Concentration; Pressoreceptors; Rats; Rats, Sprague-Dawley; Stimulation, Chemical

2012
Diminished cortical inhibition in an aging mouse model of chronic tinnitus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Nov-14, Volume: 32, Issue:46

    Topics: Acoustic Stimulation; Aging; Animals; Auditory Cortex; Auditory Threshold; Cerebral Cortex; Chronic Disease; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Flavoproteins; GABA Antagonists; gamma-Aminobutyric Acid; Hearing Loss, Noise-Induced; Male; Mice; Mice, Inbred CBA; N-Methylaspartate; Neural Inhibition; Pyridazines; Receptors, GABA-A; Reflex, Startle; Tinnitus

2012
Sustained potentiation by substance P of NMDA-activated current in rat primary sensory neurons.
    Brain research, 2004, Jun-04, Volume: 1010, Issue:1-2

    Topics: Animals; Benzylamines; Calcium Signaling; Cell Membrane; Cells, Cultured; Chelating Agents; Chronic Disease; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Enzyme Inhibitors; Ganglia, Spinal; Membrane Potentials; Models, Biological; N-Methylaspartate; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Pain; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Substance P; Sulfonamides

2004
Chronic stress attenuates GABAergic inhibition and alters gene expression of parvocellular neurons in rat hypothalamus.
    The European journal of neuroscience, 2004, Volume: 20, Issue:6

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Northern; Body Weight; Chronic Disease; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gene Expression; Hypothalamus; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Organ Size; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Physiological; Time Factors

2004
Neuroprotection by the PGE2 EP2 receptor in permanent focal cerebral ischemia.
    Annals of neurology, 2005, Volume: 57, Issue:5

    Topics: Aging; Alprostadil; Animals; Brain Ischemia; Cell Death; Cerebral Infarction; Chronic Disease; Excitatory Amino Acid Agonists; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype

2005
Glutamate-induced activation of nitric oxide synthase is impaired in cerebral cortex in vivo in rats with chronic liver failure.
    Journal of neurochemistry, 2007, Volume: 102, Issue:1

    Topics: Ammonia; Animals; Blotting, Western; Cerebral Cortex; Chronic Disease; Cyclic GMP; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Liver Failure; Male; N-Methylaspartate; Nitrates; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

2007
Loss of hippocampal neuronal nitric oxide synthase contributes to the stress-related deficit in learning and memory.
    Journal of neurochemistry, 2007, Volume: 102, Issue:1

    Topics: Animals; Avoidance Learning; Blotting, Western; Chronic Disease; Female; Hippocampus; Immunohistochemistry; Isoenzymes; Learning Disabilities; Memory Disorders; Mice; Mice, Inbred BALB C; N-Methylaspartate; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase Type I; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Reactive Oxygen Species; Signal Transduction; Stress, Psychological

2007
Intrauterine hypoxia-ischemia increases N-methyl-D-aspartate-induced cGMP formation and glutamate accumulation in cultured rat cerebellar granule cells.
    Pediatric research, 1995, Volume: 38, Issue:1

    Topics: Animals; Arginine; Brain Ischemia; Cells, Cultured; Cerebellar Diseases; Chronic Disease; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fetal Hypoxia; Gestational Age; Glutamic Acid; Hypoxia, Brain; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley

1995
Chronic mild acidosis specifically reduces functional expression of N-methyl-D-aspartate receptors and increases long-term survival in primary cultures of cerebellar granule cells.
    Neuroscience, 1994, Volume: 63, Issue:2

    Topics: Acidosis; Animals; Cell Survival; Cells, Cultured; Cerebellum; Chronic Disease; Electrophysiology; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors

1994
Pre treatment with MK-801, a non-competitive NMDA antagonist, prevents development of mechanical hyperalgesia in a rat model of chronic neuropathy, but not in a model of chronic inflammation.
    Neuroscience letters, 1994, Jan-03, Volume: 165, Issue:1-2

    Topics: Animals; Chronic Disease; Dizocilpine Maleate; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; N-Methylaspartate; Nervous System Diseases; Nociceptors; Physical Stimulation; Rats; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve

1994
A segmental chronic pain syndrome in rats associated with intrathecal infusion of NMDA: evidence for selective action in the dorsal horn.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1994, Volume: 21, Issue:1

    Topics: Animals; Anterior Horn Cells; Axons; Behavior, Animal; Chronic Disease; Electrophysiology; Injections, Spinal; Magnesium Sulfate; Male; Motor Neurons; N-Methylaspartate; Nerve Fibers; Nerve Fibers, Myelinated; Neural Conduction; Neural Pathways; Neurons, Afferent; Nociceptors; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord

1994
The effect of NMDA antagonists on footshock-induced fighting behavior in chronically stressed rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1997, Volume: 48, Issue:1

    Topics: Aggression; Animals; Chronic Disease; Dizocilpine Maleate; Electroshock; Excitatory Amino Acid Antagonists; Exploratory Behavior; Male; Memantine; N-Methylaspartate; Rats; Rats, Wistar; Stress, Psychological

1997
Seizure-induced hippocampal damage and chronic epilepsy: a hebbian theory of epileptogenesis.
    Advances in neurology, 1999, Volume: 79

    Topics: Animals; Chronic Disease; Dentate Gyrus; Epilepsy; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Kindling, Neurologic; Long-Term Potentiation; Models, Neurological; Mossy Fibers, Hippocampal; N-Methylaspartate; Neural Inhibition; Neural Pathways; Rats; Rats, Wistar; Status Epilepticus; Synapses

1999
Effects of amitriptyline, amitriptylinoxide, doxepine and clozapine on N-methyl-D-aspartate-evoked release of [3H]-acetylcholine in rat caudatoputamen.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:10

    Topics: Acetylcholine; Algorithms; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Caudate Nucleus; Chronic Disease; Clozapine; Doxepin; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Pain; Putamen; Rats; Rats, Wistar

1999
Impaired excitatory transmission in the striatum of rats chronically intoxicated with manganese.
    Experimental neurology, 2001, Volume: 172, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cerebral Cortex; Chronic Disease; Corpus Striatum; Electric Stimulation; Excitatory Amino Acid Agonists; Liver; Male; Manganese; Manganese Poisoning; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Reference Values; Synapses; Synaptic Transmission

2001
Alcohol induction of liver nuclear ethanol and N-nitrosodimethylamine metabolism to reactive metabolites.
    Teratogenesis, carcinogenesis, and mutagenesis, 2002, Volume: 22, Issue:2

    Topics: Acetaldehyde; Animals; Biotransformation; Carbon Isotopes; Cell Nucleus; Chronic Disease; Cytochrome P-450 CYP2E1; Diet; Dimethylnitrosamine; DNA; Ethanol; Formaldehyde; Lipid Metabolism; Liver; Male; Microsomes, Liver; N-Methylaspartate; NADP; Rats; Rats, Sprague-Dawley

2002