n-methylaspartate has been researched along with Brain Injuries in 123 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.63) | 18.7374 |
| 1990's | 24 (19.51) | 18.2507 |
| 2000's | 65 (52.85) | 29.6817 |
| 2010's | 29 (23.58) | 24.3611 |
| 2020's | 3 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, J; Hao, B; He, Y; Li, Y; Miller, B; Mori, Y; Su, Z; Sun, B; Wu, G; Xie, J; Yu, AS; Yue, L; Yue, Z; Zong, P | 1 |
| Pavlinova, EB; Savchenko, OA | 1 |
| Hu, CP; Liu, HQ; Luo, XJ; Peng, J; Yang, XY; Zhang, YY; Zhang, Z | 1 |
| Lee, JQ; McDonald, RJ; Sutherland, RJ | 2 |
| Amini, M; Baudry, M; Beique, JC; Bergeron, R; Farazifard, R; Greer, PA; Hage, F; Lagace, DC; Ma, CL; Park, DS; Savitt, JM; Slack, RS; Vanderluit, J; Zhang, Y; Zhu, G; Zoltewicz, JS | 1 |
| Bott, JB; Cassel, JC; Cosquer, B; Héraud, C; Kelche, C; Mathis, C; Zerbinatti, C | 1 |
| Hagberg, H; Krishnamurthy, R; Mallard, C; Nair, S; Thornton, C | 1 |
| Brann, D; Dhandapani, KM; Farook, JM; Markand, S; Sen, N; Sen, T; Shields, J; Smith, SB; Tawfik, A | 1 |
| Boeck, CR; Carbonera, LS; Constantino, LC; Garcez, ML; Milioli, ME; Rezin, GT; Scaini, G; Streck, EL | 1 |
| Choi, DJ; Choi, I; Jeong, HK; Ji, KM; Joe, EH; Jou, I; Min, KJ | 1 |
| Çalişir, M; Gürgen, SG; Sayın, O; Sönmez, A | 1 |
| Fei, Z; Han, F; Han, H; Liu, MD; Luo, P; Rao, W; Su, N; Wang, Y; Yao, LB; Zhang, C | 1 |
| Creeden, JF; Fitzpatrick, CJ; Morrow, JD; Perrine, SA | 1 |
| Ji, J; Maren, S | 1 |
| Aggleton, JP; Albasser, MM; Davies, M; Futter, JE | 1 |
| Acarin, L; Burgaya, F; Castellano, B; Gonzalez, B; Gonzalez, P; Peluffo, H | 1 |
| Acarin, L; Campuzano, O; Castellano, B; Castillo-Ruiz, MM; Gonzalez, B | 1 |
| Ahmad, AS; Doré, S; Maruyama, T; Narumiya, S; Saleem, S | 1 |
| Hamill, CE; Lyuboslavsky, P; Mannaioni, G; Sastre, AA; Traynelis, SF | 1 |
| Baik, EJ; Jang, YN; Jung, YS; Kim, CH; Lee, SH; Moon, CH | 1 |
| Balleine, BW; Ostlund, SB; Winterbauer, NE | 1 |
| Ai, J; Baker, AJ; Bell, JD; Park, E | 1 |
| Boeck, CR; Constantino, LC; Costa, T; Herculano, B; Mendonça, BP; Pereira, JG; Tasca, CI | 1 |
| Aggleton, JP; Davies, M; Pothuizen, HH; Vann, SD | 1 |
| Katayama, T; Komatsu, Y; Minami, M; Oguma, T; Sakaguchi, E; Uehara, T | 1 |
| Izumi, Y; Zorumski, CF | 1 |
| Jahani-Asl, A; MacLaurin, JG; McBride, HM; Park, DS; Pilon-Larose, K; Slack, RS; Xu, W | 1 |
| Fang, H; Guo, J; Peng, S; Yu, X | 1 |
| Hayes, RL; Kobeissy, F; Liu, MC; Wang, KK; Zhang, Z; Zheng, W | 1 |
| Kelley, BG; Luoma, JI; Mermelstein, PG | 1 |
| Allen, CP; Leri, F | 1 |
| Armstead, WM; Cines, DB; Higazi, AA; Kiessling, JW; Riley, J | 1 |
| Cho, IH; Hong, HS; Kim, HS; Lee, CK; Lee, JM; Lee, KS; Noh, SJ; Suh, YH | 1 |
| Cho, GS; Choi, IY; Choi, WJ; Hwang, S; Jeong, LS; Ju, C; Kim, WK; Lee, HW; Lee, JC | 1 |
| Abe, T; Anrather, J; Gallo, EF; Gooden, C; Iadecola, C; Kawano, T; Orio, M; Zhou, P | 1 |
| Arbeloa, J; Gottlieb, M; Matute, C; Pérez-Samartín, A | 1 |
| Abraini, JH; Colomb, DG; David, HN; Degoulet, M; Haelewyn, B; Risso, JJ | 1 |
| Bavaresco, DV; Boeck, CR; Comim, CM; Damiani-Neves, M; Moojen, VK; Pescador, BB; Quevedo, J | 1 |
| Anagli, J; Cagmat, EB; Guingab-Cagmat, JD; Kobeissy, FH; Newsom, K; Vakulenko, A; Wang, KK; Zoltewicz, S | 1 |
| Bazhenov, M; Sejnowski, TJ; Volman, V | 1 |
| Acarin, L; Castellano, B; González, B; Peluffo, H | 1 |
| Armstead, WM; Kulkarni, M | 1 |
| Franks, NP; Ma, D; Maze, M; Wilhelm, S | 1 |
| Armstead, WM | 5 |
| Hayashi, Y; Inoue, K; Kadowaki, T; Kagamiishi, Y; Katsube, N; Mizoguchi, Y; Moriguchi, S; Nabekura, J; Nakanishi, H; Tomimatsu, Y; Watanabe, S; Yamamoto, K | 1 |
| Cosi, C; Guerin, K; Koek, W; Marien, M; Rollet, K | 1 |
| Aarts, MM; Arundine, M; Chopra, GK; Lei, S; MacDonald, JF; Tymianski, M; Wrong, A | 1 |
| Arundine, M; Tymianski, M | 1 |
| Aggleton, JP; Amin, E; Jenkins, TA; Vann, SD | 1 |
| Aggleton, JP; Vann, SD | 2 |
| Aarts, M; Arundine, M; Lau, A; Tymianski, M | 1 |
| Fandrey, J; Härting, M; Kou, W; Niemi, MB; Pacheco-López, G; Schedlowski, M | 1 |
| Wei, EQ; Zhang, LH | 1 |
| Ampo, K; Kadono, C; Kiryu-Seo, S; Kiyama, H; Konishi, H; Maeda, M; Ohba, N | 1 |
| Armstead, WM; Cines, DB; Higazie, AA | 1 |
| Bardgett, ME; Foltz, RF; Griffith, MS; Hopkins, JA; Massie, CM; O'Connell, SM | 1 |
| Harley, CW; Milway, SJ; Peddle, R; Squires, AS | 1 |
| Hines, DJ; Whishaw, IQ | 1 |
| Coover, GD; Trivedi, MA | 1 |
| Feldon, J; Pothuizen, HH; Yee, BK | 1 |
| Humpel, C; Zassler, B | 1 |
| Kumar, VM; Mallick, HN; Srividya, R | 1 |
| Geddes-Klein, DM; Meaney, DF; Schiffman, KB | 1 |
| Allen, K; Doré, FY; Goulet, S; Potvin, O; Thibaudeau, G | 1 |
| Cassel, JC; Cosquer, B; Ferry, B; Galani, R; Herbeaux, K; Jeltsch, H; Majchrzak, M; Pernon, A; Traissard, N | 1 |
| Lukoyanov, NV; Lukoyanova, EA | 1 |
| Daniel, PB; Medcalf, RL; Niego, B; Samson, AL; Weiss, TW | 1 |
| Arundine, M; Jones, M; Lau, A; Sun, HS; Tymianski, M | 1 |
| Chen, Z; Ding, Q; Wei, EQ; Zhang, WP; Zhang, YJ | 1 |
| Bernaudin, M; Bouët, V; Boulouard, M; Freret, T; Haelewyn, B; Pacary, E; Schumann-Bard, P | 1 |
| Ahmad, AS; Ahmad, M; Doré, S; Maruyama, T; Narumiya, S; Zhuang, H | 1 |
| Abe, T; Anrather, J; Girouard, H; Iadecola, C; Kawano, T; Kunz, A; Zhou, P | 1 |
| Fang, T; Hayes, RL; Kobeissy, FH; Ottens, AK; Sadasivan, S; Wang, KK; Zhang, Z | 1 |
| Franz, TM; Schoenbaum, G; Singh, T; Stalnaker, TA | 1 |
| Deniau, JM; Ezan, P; Glowinski, J; Jabourian, M; Kemel, ML; Pérez, S | 1 |
| Foong, N; Hong, NS; King, AL; McDonald, RJ; Rizos, Z | 1 |
| Benavides, J; Dubois, A; Scatton, B | 1 |
| Botscheller, ML; DeKosky, ST; Marion, DW; Palmer, AM; Styren, SD; Swedlow, PE | 1 |
| Balázs, R; Nicolay, K; van Lookeren Campagne, M; Verheul, JB | 1 |
| Balázs, R; Berkelbach van der Sprenkel, JW; Nicolay, K; Tamminga, KS; Tulleken, CA; van Lookeren Campagne, M; Verheul, HB | 1 |
| Anderson, DK; Kim-Lee, MH; Stokes, BT | 1 |
| Barks, JD; Nair, MP; Schwartz, SA; Silverstein, FS | 1 |
| Ginsberg, MD | 1 |
| Bernert, H; Turski, L | 1 |
| Panter, SS; Regan, RF | 1 |
| Barks, JD; Davidson, BL; Hagan, P; Roessler, B; Silverstein, FS; Yabut, M | 1 |
| Ellis, EF; Rzigalinski, BA; Satin, LS; Zhang, L | 1 |
| Ikonomidou, C; Turski, L | 1 |
| McBurney, RN | 1 |
| Hamm, RJ; Temple, MD | 1 |
| Duva, CA; Floresco, SB; Lao, TL; Phillips, AG; Pinel, JP; Wunderlich, GR | 1 |
| Alagarsamy, S; DeWitt, DS; Johnson, KM | 1 |
| Boulu, RG; Lecanu, L; Margaill, I; Plotkine, M; Verrecchia, C | 1 |
| Galasso, JM; Harrison, JK; Silverstein, FS | 1 |
| Faddis, BT; Goldberg, MP; Hasbani, MJ; Hyrc, KL; Romano, C | 1 |
| Bittigau, P; Hübner, C; Ikonomidou, C; Ishimaru, MJ; Olney, JW; Pohl, D; Stadthaus, D; Turski, L | 1 |
| Ellis, EF; Moore, SF; Rzigalinski, BA; Weber, JT; Willoughby, KA | 1 |
| Galasso, JM; Martin, D; Silverstein, FS; Wang, P | 1 |
| Butler, P; Chenard, BL; Frost White, W; Jaw-Tsai, SS; Menniti, FS; Pagnozzi, MJ | 1 |
| Hanley, DF; Johnson, LJ; Thakor, NV | 1 |
| Acarin, L; Castellano, B; González, B | 1 |
| Ikonomidou, C; Stefovska, V; Turski, L | 1 |
| Franklin, KB; Leri, F | 1 |
| Galasso, JM; Liu, Y; Silverstein, FS; Szaflarski, J; Warren, JS | 1 |
| Bao, W; Faden, AI; Fan, L; Knoblach, SM; Movsesyan, VA; Mullins, PG; O'Leary, DM | 1 |
| Bittigau, P; Hansen, HH; Hansen, HS; Hansen, SH; Ikonomidou, C | 1 |
| Delahunty, TM; Hamm, RJ; Lyeth, BG; Phillips, LL; Povlishock, JT; Temple, MD | 1 |
| Aggleton, JP; Baird, A; Morgan, A; Muir, JL; Warburton, EC | 1 |
| Dehghani, F; Hailer, NP; Hischebeth, GT; Korf, HW; Roser, N; Wirjatijasa, F | 1 |
| Anthony, DC; Campbell, SJ; Perry, VH; Wilcockson, DC | 1 |
| Acarin, L; Castellano, B; González, B; Paris, J | 1 |
| Faden, AI; Salzman, S | 1 |
| Faden, AI; Panter, SS | 1 |
| Johnston, MV; McDonald, JW; Trescher, WH | 1 |
| Chen, CK; Johnston, MV; McDonald, JW; Trescher, WH | 1 |
| Demediuk, P; Faden, AI; Panter, SS; Vink, R | 1 |
| Simon, RP | 1 |
7 review(s) available for n-methylaspartate and Brain Injuries
| Article | Year |
|---|---|
Death associated protein kinases: molecular structure and brain injury.
Topics: Animals; Brain Injuries; Death-Associated Protein Kinases; Humans; N-Methylaspartate; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, N-Methyl-D-Aspartate | 2013 |
Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury.
Topics: Animals; Brain Injuries; Brain Ischemia; Glutamic Acid; Humans; N-Methylaspartate; Nerve Degeneration; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2004 |
Emerging strategies for the treatment of ischemic brain injury.
Topics: Animals; Benzazepines; Body Temperature; Brain; Brain Injuries; Brain Ischemia; Calcium Channel Blockers; Dextromethorphan; Dizocilpine Maleate; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; N-Methylaspartate | 1993 |
Neurodegenerative disorders: clues from glutamate and energy metabolism.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Damage, Chronic; Brain Injuries; Brain Ischemia; Energy Metabolism; Excitatory Amino Acid Antagonists; Glutamates; Humans; N-Methylaspartate; Nerve Degeneration; Nervous System Diseases; Neurotoxins | 1996 |
Development of the NMDA ion-channel blocker, aptiganel hydrochloride, as a neuroprotective agent for acute CNS injury.
Topics: Acute Disease; Brain Injuries; Cerebrovascular Disorders; Clinical Trials as Topic; Drugs, Investigational; Glasgow Coma Scale; Guanidines; Humans; N-Methylaspartate; Neuroprotective Agents; Reference Values; Spinal Cord Injuries | 1997 |
Pharmacological strategies in CNS trauma.
Topics: Animals; Antioxidants; Brain Injuries; Calcium Channel Blockers; Free Radical Scavengers; Humans; N-Methylaspartate; Narcotic Antagonists; Receptors, Opioid; Spinal Cord Injuries; Thyrotropin-Releasing Hormone | 1992 |
Role of endogenous excitatory amino acid neurotransmitters in the pathogenesis and evolution of acute brain injury.
Topics: Acute Disease; Amino Acids; Animals; Aspartic Acid; Brain Diseases; Brain Injuries; Calcium; Calcium Channels; Humans; Meningitis; N-Methylaspartate; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
116 other study(ies) available for n-methylaspartate and Brain Injuries
| Article | Year |
|---|---|
Functional coupling of TRPM2 and extrasynaptic NMDARs exacerbates excitotoxicity in ischemic brain injury.
Topics: Animals; Brain Injuries; Ischemic Stroke; Mice; N-Methylaspartate; Peptides; Receptors, N-Methyl-D-Aspartate; TRPM Cation Channels | 2022 |
[Long-term neurological outcomes in premature children with excitotoxic brain damage].
Topics: Antibodies; Brain; Brain Injuries; Child; Female; Glutamic Acid; Humans; Infant; Infant, Newborn; Infant, Premature; Lactates; N-Methylaspartate; Pregnancy; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2022 |
The Weakened Interaction Between HECTD4 and GluN2B in Ischemic Stroke Promotes Calcium Overload and Brain Injury Through a Mechanism Involving the Decrease of GluN2B and MALT1 Ubiquitination.
Topics: Animals; Brain Injuries; Calcium; Ischemic Stroke; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Ubiquitin-Protein Ligases; Ubiquitination | 2023 |
Hippocampal damage causes retrograde but not anterograde memory loss for context fear discrimination in rats.
Topics: Amnesia, Retrograde; Analysis of Variance; Animals; Brain Injuries; Conditioning, Classical; Discrimination, Psychological; Electroshock; Excitatory Amino Acid Agonists; Fear; Freezing Reaction, Cataleptic; Hippocampus; Male; N-Methylaspartate; Rats; Rats, Long-Evans | 2017 |
Hippocampal Damage Causes Retrograde Amnesia and Slower Acquisition of a Cue-Place Discrimination in a Concurrent Cue-Place Water Task in Rats.
Topics: Amnesia, Retrograde; Animals; Behavior, Animal; Brain Injuries; Cues; Discrimination Learning; Hippocampus; Male; Maze Learning; N-Methylaspartate; Rats; Rats, Long-Evans | 2019 |
Conditional disruption of calpain in the CNS alters dendrite morphology, impairs LTP, and promotes neuronal survival following injury.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Brain; Brain Injuries; Bromodeoxyuridine; Calpain; Cell Death; Dendrites; Disease Models, Animal; Electric Stimulation; Embryo, Mammalian; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Intermediate Filament Proteins; Long-Term Potentiation; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Nerve Tissue Proteins; Nestin; Neurons; Patch-Clamp Techniques; Phosphotransferases; Psychomotor Performance; RNA, Messenger; Silver Staining; Transfection; Tyrosine 3-Monooxygenase | 2013 |
Reduced plasticity and mild cognitive impairment-like deficits after entorhinal lesions in hAPP/APOE4 mice.
Topics: Age Factors; Amyloid beta-Protein Precursor; Animals; Apolipoprotein E4; Atrophy; Brain Injuries; Cognition Disorders; Dark Adaptation; Entorhinal Cortex; Excitatory Amino Acids; Gene Expression Regulation; Humans; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Recognition, Psychology; Synapses | 2013 |
GADD34 induces cell death through inactivation of Akt following traumatic brain injury.
Topics: Activating Transcription Factor 4; Animals; Apoptosis; Brain Injuries; Cells, Cultured; Cerebral Cortex; Endoplasmic Reticulum Stress; Excitatory Amino Acid Agonists; Homeostasis; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Phosphorylation; Primary Cell Culture; Promoter Regions, Genetic; Protein Binding; Protein Phosphatase 1; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; TNF Receptor-Associated Factor 6; Transcriptional Activation; Ubiquitination | 2013 |
Mitochondrial respiratory chain and creatine kinase activities following trauma brain injury in brain of mice preconditioned with N-methyl-D-aspartate.
Topics: Animals; Brain Injuries; Cerebellum; Cerebral Cortex; Creatine Kinase; Excitatory Amino Acid Agonists; Male; Mice; Mitochondria; Mitochondrial Membranes; N-Methylaspartate; Oxidative Stress; Receptors, N-Methyl-D-Aspartate | 2013 |
Astrogliosis is a possible player in preventing delayed neuronal death.
Topics: Animals; Astrocytes; Biomarkers; Brain Injuries; Cell Communication; Cell Death; Cerebral Cortex; Excitatory Amino Acid Transporter 2; Glial Fibrillary Acidic Protein; Gliosis; Glutamate-Ammonia Ligase; Kainic Acid; Male; N-Methylaspartate; Neurons; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; S100 Calcium Binding Protein beta Subunit | 2014 |
Neuroprotective effects of MK-801 against traumatic brain injury in immature rats.
Topics: Animals; Brain Injuries; Brain-Derived Neurotrophic Factor; Cognition Disorders; Dizocilpine Maleate; Hippocampus; Memory; N-Methylaspartate; Nerve Growth Factor; Neurons; Neuroprotective Agents; Rats, Wistar | 2015 |
Scaffolding protein Homer1a protects against NMDA-induced neuronal injury.
Topics: Animals; Brain Injuries; Calcium; Carrier Proteins; Cerebral Cortex; Disks Large Homolog 4 Protein; Gene Expression Regulation; Guanylate Kinases; HEK293 Cells; Homer Scaffolding Proteins; Homozygote; Humans; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurons; Nitric Oxide Synthase Type I; Oxidative Stress; Primary Cell Culture; Protein Binding; Protein Isoforms; Protein Transport; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Stereotaxic Techniques | 2015 |
Lesions of the ventral hippocampus attenuate the acquisition but not expression of sign-tracking behavior in rats.
Topics: Animals; Brain Injuries; Chromatography, High Pressure Liquid; Conditioning, Classical; Cues; Dopamine; Excitatory Amino Acid Agonists; Hippocampus; Male; Motivation; N-Methylaspartate; Nucleus Accumbens; Probability; Rats; Rats, Sprague-Dawley; Reaction Time; Reinforcement, Psychology; Signal Detection, Psychological | 2016 |
Lesions of the entorhinal cortex or fornix disrupt the context-dependence of fear extinction in rats.
Topics: Acoustic Stimulation; Animals; Behavior, Animal; Brain Injuries; Conditioning, Classical; Electrolysis; Entorhinal Cortex; Extinction, Psychological; Fear; Fornix, Brain; Freezing Reaction, Cataleptic; Male; N-Methylaspartate; Neurotoxins; Rats; Rats, Long-Evans | 2008 |
Magnitude of the object recognition deficit associated with perirhinal cortex damage in rats: Effects of varying the lesion extent and the duration of the sample period.
Topics: Animals; Behavior, Animal; Brain Injuries; Cerebral Cortex; Discrimination, Psychological; Exploratory Behavior; Linear Models; Male; N-Methylaspartate; Pattern Recognition, Visual; Perceptual Disorders; Photic Stimulation; Rats; Time Factors | 2009 |
Interleukin-10 and interleukin-10 receptor-I are upregulated in glial cells after an excitotoxic injury to the postnatal rat brain.
Topics: Animals; Animals, Newborn; Blood Vessels; Brain Injuries; Ectodysplasins; Excitatory Amino Acid Agonists; Female; Glial Fibrillary Acidic Protein; Interleukin-10; Interleukin-10 Receptor alpha Subunit; Male; N-Methylaspartate; Neuroglia; Phosphopyruvate Hydratase; Plant Lectins; Rats; Rats, Long-Evans; RNA, Messenger; Time Factors; Up-Regulation | 2009 |
Increased levels of proinflammatory cytokines in the aged rat brain attenuate injury-induced cytokine response after excitotoxic damage.
Topics: Aging; Animals; Astrocytes; Brain; Brain Injuries; Cerebral Cortex; Corpus Striatum; Interleukin-1beta; Interleukin-6; Macrophages; Male; Microglia; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha | 2009 |
PGF(2alpha) FP receptor contributes to brain damage following transient focal brain ischemia.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Brain Infarction; Brain Injuries; Brain Ischemia; Disease Models, Animal; Excitatory Amino Acid Agonists; Latanoprost; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nervous System Diseases; Prostaglandins F, Synthetic; Receptors, Prostaglandin; Receptors, Prostaglandin E | 2009 |
Protease-activated receptor 1-dependent neuronal damage involves NMDA receptor function.
Topics: Analysis of Variance; Animals; Brain Injuries; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Guanidines; Injections, Intraventricular; Ischemic Attack, Transient; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurons; Oligopeptides; Pregnancy; Rats; Receptor, PAR-1; Receptors, N-Methyl-D-Aspartate | 2009 |
Calpain-mediated N-cadherin proteolytic processing in brain injury.
Topics: Animals; Animals, Newborn; beta Catenin; Biotinylation; Brain Injuries; Cadherins; Calcium; Calpain; Cells, Cultured; Disease Models, Animal; Dizocilpine Maleate; Embryo, Mammalian; Endocytosis; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Green Fluorescent Proteins; In Vitro Techniques; Ionomycin; Ionophores; Mice; Models, Biological; Mutation; N-Methylaspartate; Neurons; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Signal Transduction; Subcellular Fractions; Transfection; Wnt Proteins | 2009 |
Evidence of action sequence chunking in goal-directed instrumental conditioning and its dependence on the dorsomedial prefrontal cortex.
Topics: Animals; Association Learning; Behavior, Animal; Brain Injuries; Choice Behavior; Conditioning, Classical; Discrimination Learning; Excitatory Amino Acid Agonists; Female; Microinjections; N-Methylaspartate; Prefrontal Cortex; Rats; Rats, Long-Evans; Reaction Time | 2009 |
PICK1-mediated GluR2 endocytosis contributes to cellular injury after neuronal trauma.
Topics: Animals; Brain Injuries; Carrier Proteins; Cells, Cultured; Cytoskeletal Proteins; Endocytosis; N-Methylaspartate; Nuclear Proteins; Protein Binding; Protein Transport; Rats; Rats, Wistar; Receptors, AMPA; Tissue Culture Techniques | 2009 |
N-methyl-D-aspartate preconditioning improves short-term motor deficits outcome after mild traumatic brain injury in mice.
Topics: Animals; Brain Injuries; Cell Count; Cerebellum; Cerebral Cortex; Disease Models, Animal; DNA Fragmentation; Dyskinesias; Male; Mice; Motor Activity; N-Methylaspartate; Neuroprotective Agents; Postural Balance; Severity of Illness Index; Time Factors; Treatment Outcome | 2010 |
Effects of selective granular retrosplenial cortex lesions on spatial working memory in rats.
Topics: Animals; Brain Injuries; Choice Behavior; Cues; Dark Adaptation; Gyrus Cinguli; Male; Maze Learning; Memory Disorders; Memory, Short-Term; N-Methylaspartate; Phosphopyruvate Hydratase; Rats; Reinforcement, Psychology; Rotation; Spatial Behavior; Statistics, Nonparametric | 2010 |
Sustained activation of ERK signaling in astrocytes is critical for neuronal injury-induced monocyte chemoattractant protein-1 production in rat corticostriatal slice cultures.
Topics: Animals; Astrocytes; Brain Injuries; Butadienes; Cerebral Cortex; Chemokine CCL2; Corpus Striatum; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; In Vitro Techniques; MAP Kinase Signaling System; N-Methylaspartate; Neurons; Nitriles; Phosphorylation; Rats; Rats, Wistar; Time Factors | 2010 |
Neuroprotective effects of pyruvate following NMDA-mediated excitotoxic insults in hippocampal slices.
Topics: Adenosine Triphosphate; Aging; Animals; Brain Injuries; CA1 Region, Hippocampal; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glyceraldehyde-3-Phosphate Dehydrogenases; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Nitric Oxide; Pyruvic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 2010 |
The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity.
Topics: Animals; Brain Injuries; Cell Death; Cell Survival; Cerebellum; Cytotoxins; Excitatory Amino Acid Agonists; GTP Phosphohydrolases; Mice; Mitochondrial Membranes; Mitochondrial Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons | 2011 |
Basal metallothionein-I/II protects against NMDA-mediated oxidative injury in cortical neuron/astrocyte cultures.
Topics: Animals; Animals, Newborn; Astrocytes; Brain Injuries; Cells, Cultured; Cerebral Cortex; Down-Regulation; Membrane Potential, Mitochondrial; Metallothionein; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Oxidative Stress; Reactive Oxygen Species; Up-Regulation | 2011 |
Dual vulnerability of tau to calpains and caspase-3 proteolysis under neurotoxic and neurodegenerative conditions.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain; Brain Injuries; Calpain; Caspase 3; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Gene Expression Regulation; Male; Molecular Weight; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxicity Syndromes; Neurotoxins; Peptide Hydrolases; Protein Isoforms; Rats; tau Proteins | 2011 |
Progesterone inhibition of voltage-gated calcium channels is a potential neuroprotective mechanism against excitotoxicity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Brain; Brain Injuries; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gene Expression; Genes, Reporter; Glutamic Acid; Luciferases; Male; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; NFATC Transcription Factors; Nifedipine; Potassium; Progesterone; Rats; Rats, Sprague-Dawley | 2011 |
Excitotoxic lesions to the prefrontal cortex of Sprague-Dawley rats do not impair response matching.
Topics: Animals; Brain Injuries; Conditioning, Operant; Infusions, Intraventricular; Male; N-Methylaspartate; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reversal Learning; Reward | 2011 |
tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK.
Topics: Animals; Animals, Newborn; Anthracenes; Brain Injuries; Butadienes; Drug Interactions; Female; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; N-Methylaspartate; Nitriles; Oligopeptides; Papaverine; Peptides; Pia Mater; Pyridines; Swine; Tissue Plasminogen Activator; Up-Regulation; Vasoconstriction; Vasodilation | 2011 |
SP-8203 shows neuroprotective effects and improves cognitive impairment in ischemic brain injury through NMDA receptor.
Topics: Acetamides; Animals; Animals, Newborn; Brain Injuries; Brain Ischemia; Cells, Cultured; Cognition Disorders; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Neuroprotective Agents; Quinazolinones; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2011 |
A3 adenosine receptor agonist reduces brain ischemic injury and inhibits inflammatory cell migration in rats.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Brain Infarction; Brain Injuries; Brain Ischemia; Cell Movement; Chemokine CCL2; Glucose; Inflammation; Interleukin-1beta; Lipopolysaccharides; Male; Microglia; Monocytes; N-Methylaspartate; Protein Transport; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; rho GTP-Binding Proteins; Thionucleosides; Tumor Necrosis Factor-alpha | 2011 |
Purinergic signaling induces cyclooxygenase-1-dependent prostanoid synthesis in microglia: roles in the outcome of excitotoxic brain injury.
Topics: Adenosine Triphosphate; Animals; Brain Injuries; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Gene Deletion; Membrane Proteins; Mice; Mice, Inbred C57BL; Microglia; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide Synthase Type I; Prostaglandins; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Purinergic P2X7; Signal Transduction; Time Factors; Treatment Outcome | 2011 |
P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Brain Injuries; Calcium; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Fluoresceins; Glucose; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Membrane Potentials; N-Methylaspartate; Neurologic Examination; Neurons; Organic Chemicals; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Purinergic P2X Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X7; Rosaniline Dyes; Tetrazolium Salts | 2012 |
Ex vivo and in vivo neuroprotection induced by argon when given after an excitotoxic or ischemic insult.
Topics: Animals; Argon; Brain; Brain Injuries; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Infarction, Middle Cerebral Artery; Male; Models, Statistical; N-Methylaspartate; Neurons; Neuroprotective Agents; Oxygen; Rats; Rats, Sprague-Dawley; Synapses | 2012 |
NMDA preconditioning prevents object recognition memory impairment and increases brain viability in mice exposed to traumatic brain injury.
Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Brain Injuries; Cell Survival; Depression; Hippocampus; Male; Memory Disorders; Mice; Motor Activity; N-Methylaspartate; Permeability; Recognition, Psychology; Visual Perception | 2012 |
In vitro MS-based proteomic analysis and absolute quantification of neuronal-glial injury biomarkers in cell culture system.
Topics: Animals; Apoptosis; Biomarkers; Brain Injuries; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Glial Fibrillary Acidic Protein; Marine Toxins; Mass Spectrometry; N-Methylaspartate; Necrosis; Neuroglia; Neurons; Oxocins; Protein Interaction Maps; Proteomics; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Ubiquitin Thiolesterase | 2012 |
Divide and conquer: functional segregation of synaptic inputs by astrocytic microdomains could alleviate paroxysmal activity following brain trauma.
Topics: Astrocytes; Brain Injuries; Humans; Models, Theoretical; N-Methylaspartate; Synapses; Tumor Necrosis Factor-alpha | 2013 |
Expression of inducible nitric oxide synthase and cyclooxygenase-2 after excitotoxic damage to the immature rat brain.
Topics: Animals; Brain Injuries; Cell Death; Cerebral Cortex; Cyclooxygenase 2; Excitatory Amino Acid Agonists; Immunohistochemistry; Isoenzymes; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Long-Evans; Time Factors | 2002 |
Relationship between NOC/oFQ, dynorphin, and COX-2 activation in impaired NMDA cerebrovasodilation after brain injury.
Topics: Animals; Animals, Newborn; Brain Injuries; Cyclooxygenase 2; Dynorphins; Enzyme Activation; Female; Glutamic Acid; Indomethacin; Isoenzymes; Male; N-Methylaspartate; Naltrexone; Nitrobenzenes; Nociceptin; Opioid Peptides; Pia Mater; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Superoxides; Swine; Vasodilation | 2002 |
Neuroprotective and neurotoxic properties of the 'inert' gas, xenon.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Biomarkers; Brain; Brain Injuries; Dizocilpine Maleate; Female; Gene Expression; Haloperidol; Ketamine; Models, Animal; N-Methylaspartate; Neuroprotective Agents; Nitrous Oxide; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Xenon | 2002 |
Age dependent NMDA contribution to impaired hypotensive cerebral hemodynamics following brain injury.
Topics: Aging; Animals; Animals, Newborn; Blood Chemical Analysis; Brain Injuries; Cerebral Arteries; Cerebrovascular Circulation; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Homeostasis; Hypotension; Male; Microspheres; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Swine | 2002 |
PTK, ERK and p38 MAPK contribute to impaired NMDA-induced vasodilation after brain injury.
Topics: Animals; Animals, Newborn; Brain Injuries; Dose-Response Relationship, Drug; Female; Male; Meningeal Arteries; Mitogen-Activated Protein Kinases; N-Methylaspartate; p38 Mitogen-Activated Protein Kinases; Pia Mater; Protein-Tyrosine Kinases; Swine; Vasodilation | 2003 |
Potentiation of NMDA receptor-mediated synaptic responses by microglia.
Topics: Animals; Animals, Newborn; Brain; Brain Injuries; Cells, Cultured; Culture Media, Conditioned; Electric Stimulation; Encephalitis; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Microglia; Molecular Weight; N-Methylaspartate; Nerve Tissue Proteins; Organ Culture Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2003 |
The PARP inhibitor benzamide protects against kainate and NMDA but not AMPA lesioning of the mouse striatum in vivo.
Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzamides; Brain Injuries; Chromatography, High Pressure Liquid; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Time Factors | 2004 |
Enhanced vulnerability to NMDA toxicity in sublethal traumatic neuronal injury in vitro.
Topics: Animals; Brain Injuries; Cell Culture Techniques; Cerebral Cortex; Excitatory Amino Acid Agonists; Hippocampus; Mice; N-Methylaspartate; Neuroglia; Neurons; Stress, Mechanical | 2003 |
Anterior thalamic lesions stop immediate early gene activation in selective laminae of the retrosplenial cortex: evidence of covert pathology in rats?
Topics: Animals; Behavior, Animal; Brain Injuries; Cell Count; DNA-Binding Proteins; Early Growth Response Protein 1; Excitatory Amino Acid Agonists; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Gyrus Cinguli; Immediate-Early Proteins; Immunohistochemistry; Male; Maze Learning; N-Methylaspartate; Neural Pathways; Radiation Injuries, Experimental; Rats; Thalamus; Transcription Factors; Transcriptional Activation | 2004 |
Testing the importance of the retrosplenial guidance system: effects of different sized retrosplenial cortex lesions on heading direction and spatial working memory.
Topics: Animals; Behavior, Animal; Brain Injuries; Cerebral Cortex; Discrimination Learning; Excitatory Amino Acid Agonists; Head Movements; Male; Maze Learning; Memory, Short-Term; N-Methylaspartate; Neural Pathways; Orientation; Rats; Space Perception; Spatial Behavior; Time Factors | 2004 |
Vulnerability of central neurons to secondary insults after in vitro mechanical stretch.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Apoptosis; Brain Injuries; Calpain; Cell Nucleus; Cells, Cultured; Cysteine Endopeptidases; DNA; DNA Fragmentation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Situ Nick-End Labeling; In Vitro Techniques; Intracellular Membranes; Membrane Potentials; Mice; Mitochondria; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Porphyrins; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Stress, Mechanical; Superoxide Dismutase | 2004 |
Neural substrates for behaviorally conditioned immunosuppression in the rat.
Topics: Amygdala; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Brain Injuries; Brain Mapping; Cell Proliferation; Cerebral Cortex; Conditioning, Classical; Cyclosporine; Cytokines; Flow Cytometry; Hypothalamus, Middle; Immunity, Cellular; Immunosuppression Therapy; Immunosuppressive Agents; Leukocyte Count; Lymphocytes; Male; N-Methylaspartate; Neurons; Rats; Time Factors | 2005 |
ONO-1078 reduces NMDA-induced brain injury and vascular cell adhesion molecule-1 expression in rats.
Topics: Animals; Antipyrine; Brain; Brain Injuries; Cerebral Cortex; Chromones; Edaravone; Leukotriene Antagonists; Male; Microinjections; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Vascular Cell Adhesion Molecule-1 | 2005 |
The p53-independent nuclear translocation of cyclin G1 in degenerating neurons by ischemic and traumatic insults.
Topics: Animals; Brain Injuries; Brain Ischemia; Cell Death; Cells, Cultured; Cyclin G; Cyclin G1; Cyclins; Cycloheximide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Fluoresceins; Fluorescent Dyes; Gene Expression Regulation; Gerbillinae; Immunohistochemistry; In Situ Hybridization; In Situ Nick-End Labeling; Kainic Acid; Mice; Mice, Knockout; Microscopy, Immunoelectron; N-Methylaspartate; Nerve Degeneration; Neurons; Organic Chemicals; Phosphopyruvate Hydratase; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Time Factors; Tumor Suppressor Protein p53 | 2005 |
Plasminogen activators contribute to age-dependent impairment of NMDA cerebrovasodilation after brain injury.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Arteries; Brain Injuries; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agonists; N-Methylaspartate; Pia Mater; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Serine Proteinase Inhibitors; Swine; Vasoconstriction; Vasodilation | 2005 |
The effects of clozapine on delayed spatial alternation deficits in rats with hippocampal damage.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Brain Injuries; Clozapine; Hippocampus; Male; Maze Learning; Memory; Microinjections; N-Methylaspartate; Neurotoxins; Rats; Rats, Sprague-Dawley; Space Perception; Spatial Behavior; Statistics, Nonparametric; Time Factors | 2006 |
Cytotoxic lesions of the hippocampus do not impair social recognition memory in socially housed rats.
Topics: Animals; Brain Injuries; Hippocampus; Housing, Animal; Male; Microinjections; N-Methylaspartate; Neurotoxins; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Social Behavior; Social Environment; Time Factors | 2006 |
Home bases formed to visual cues but not to self-movement (dead reckoning) cues in exploring hippocampectomized rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Injuries; Cues; Exploratory Behavior; Female; Hippocampus; Motor Activity; Movement; N-Methylaspartate; Photic Stimulation; Rats; Rats, Long-Evans; Reaction Time; Space Perception; Spatial Behavior; Time Factors; Video Recording | 2005 |
Neurotoxic lesions of the dorsal and ventral hippocampus impair acquisition and expression of trace-conditioned fear-potentiated startle in rats.
Topics: Animals; Association Learning; Behavior, Animal; Brain Injuries; Conditioning, Classical; Fear; Hippocampus; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Reflex, Startle; Time Factors | 2006 |
Selective dysgranular retrosplenial cortex lesions in rats disrupt allocentric performance of the radial-arm maze task.
Topics: Animals; Behavior, Animal; Brain Injuries; Cerebral Cortex; Male; Maze Learning; N-Methylaspartate; Rats; Time Factors | 2005 |
Facilitated extinction of appetitive instrumental conditioning following excitotoxic lesions of the core or the medial shell subregion of the nucleus accumbens in rats.
Topics: Analysis of Variance; Animals; Appetite; Behavior, Animal; Brain Injuries; Conditioning, Operant; Extinction, Psychological; Male; N-Methylaspartate; Nucleus Accumbens; Rats; Rats, Wistar | 2006 |
Transplantation of NGF secreting primary monocytes counteracts NMDA-induced cell death of rat cholinergic neurons in vivo.
Topics: Analysis of Variance; Animals; Antigens, CD; Basal Nucleus of Meynert; Brain Injuries; Cell Death; Cell Survival; Cell Transplantation; Choline O-Acetyltransferase; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Transfer Techniques; In Vitro Techniques; Monocytes; N-Methylaspartate; Nerve Growth Factor; Neurons; Rats; Rats, Sprague-Dawley | 2006 |
Differences in the effects of medial and lateral preoptic lesions on thermoregulation and sleep in rats.
Topics: Animals; Body Temperature Regulation; Brain Injuries; Electroencephalography; Electromyography; Electrooculography; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Preoptic Area; Rats; Rats, Wistar; Sleep | 2006 |
Mechanisms and consequences of neuronal stretch injury in vitro differ with the model of trauma.
Topics: Animals; Brain Injuries; Calcium; Cell Culture Techniques; Cell Survival; Disease Models, Animal; Excitatory Amino Acid Agonists; N-Methylaspartate; Neurons; Permeability; Rats; Rats, Sprague-Dawley; Stress, Mechanical; Tensile Strength | 2006 |
Performance on spatial working memory tasks after dorsal or ventral hippocampal lesions and adjacent damage to the subiculum.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Injuries; Excitatory Amino Acid Agonists; Hippocampus; Linear Models; Male; Maze Learning; Memory, Short-Term; N-Methylaspartate; Rats; Rats, Long-Evans; Space Perception | 2006 |
Combined damage to entorhinal cortex and cholinergic basal forebrain neurons, two early neurodegenerative features accompanying Alzheimer's disease: effects on locomotor activity and memory functions in rats.
Topics: Acetylcholine; Analysis of Variance; Animals; Antibodies, Monoclonal; Behavior, Animal; Brain Injuries; Cell Count; Choline O-Acetyltransferase; Male; Maze Learning; Memory; Motor Activity; N-Glycosyl Hydrolases; N-Methylaspartate; Neurons; Prosencephalon; Psychomotor Performance; Rats; Rats, Long-Evans; Ribosome Inactivating Proteins, Type 1; Saporins | 2007 |
Retrosplenial cortex lesions impair acquisition of active avoidance while sparing fear-based emotional memory.
Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Brain Injuries; Conditioning, Psychological; Exploratory Behavior; Fear; Freezing Reaction, Cataleptic; Gyrus Cinguli; Male; Maze Learning; Memory; N-Methylaspartate; Rats; Rats, Wistar; Reaction Time; Time Factors | 2006 |
Oncostatin M is a neuroprotective cytokine that inhibits excitotoxic injury in vitro and in vivo.
Topics: Animals; Brain Injuries; Cerebral Cortex; Humans; Inflammation Mediators; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Oncostatin M; Receptors, Oncostatin M | 2006 |
Inhibition of caspase-mediated apoptosis by peroxynitrite in traumatic brain injury.
Topics: Animals; Apoptosis; Blotting, Western; Brain Injuries; Caspases; Cells, Cultured; Cerebral Cortex; Cytochromes c; Disease Models, Animal; Embryo, Mammalian; Enzyme Inhibitors; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Molsidomine; N-Methylaspartate; Neural Inhibition; Neurons; Nitric Oxide Donors; Peroxynitrous Acid; Physical Stimulation; Rats; Rats, Sprague-Dawley; Staurosporine | 2006 |
Cysteinyl leukotriene receptor 1 is involved in N-methyl-D-aspartate-mediated neuronal injury in mice.
Topics: Animals; Antioxidants; Antipyrine; Brain; Brain Injuries; Chromones; Edaravone; Ketamine; Male; Membrane Proteins; Mice; N-Methylaspartate; Neurons; Receptors, Leukotriene; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Up-Regulation | 2006 |
Long-term evaluation of sensorimotor and mnesic behaviour following striatal NMDA-induced unilateral excitotoxic lesion in the mouse.
Topics: Analysis of Variance; Animals; Avoidance Learning; Brain Injuries; Follow-Up Studies; Functional Laterality; Male; Maze Learning; Mice; Motor Activity; Motor Skills; N-Methylaspartate; Neostriatum; Neurotoxins; Rotarod Performance Test; Statistics, Nonparametric; Time Factors | 2007 |
Stimulation of prostaglandin E2-EP3 receptors exacerbates stroke and excitotoxic injury.
Topics: Animals; Body Temperature; Brain Infarction; Brain Injuries; Cerebrovascular Circulation; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype | 2007 |
iNOS-derived NO and nox2-derived superoxide confer tolerance to excitotoxic brain injury through peroxynitrite.
Topics: Animals; Body Temperature; Brain; Brain Injuries; Carotid Arteries; Guanidines; Ischemic Preconditioning; Ligation; Lipopolysaccharides; Male; Membrane Glycoproteins; Metalloporphyrins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Superoxides; Tyrosine | 2007 |
Calpain-mediated collapsin response mediator protein-1, -2, and -4 proteolysis after neurotoxic and traumatic brain injury.
Topics: Adaptor Proteins, Signal Transducing; Animals; Brain; Brain Injuries; Calpain; Caspase 3; Cell Death; Cells, Cultured; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; Excitatory Amino Acid Agonists; Hippocampus; Immunoblotting; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; L-Lactate Dehydrogenase; Marine Toxins; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Oxocins; Phosphoproteins; Rats; Rats, Sprague-Dawley | 2007 |
Basolateral amygdala lesions abolish orbitofrontal-dependent reversal impairments.
Topics: Amygdala; Analysis of Variance; Animals; Behavior, Animal; Brain Injuries; Choice Behavior; Discrimination Learning; Frontal Lobe; Male; N-Methylaspartate; Odorants; Rats; Rats, Long-Evans; Reversal Learning | 2007 |
Impact of 6-hydroxydopamine lesions and cocaine exposure on mu-opioid receptor expression and regulation of cholinergic transmission in the limbic-prefrontal territory of the rat dorsal striatum.
Topics: Acetylcholine; Animals; Behavior, Animal; Brain Injuries; Circadian Rhythm; Cocaine; Corpus Striatum; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agonists; Functional Laterality; Male; Models, Neurological; N-Methylaspartate; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Tritium | 2007 |
Neurotoxic lesions of the medial prefrontal cortex or medial striatum impair multiple-location place learning in the water task: evidence for neural structures with complementary roles in behavioural flexibility.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Injuries; Corpus Striatum; Learning Disabilities; Maze Learning; N-Methylaspartate; Neurotoxins; Prefrontal Cortex; Quinolinic Acid; Rats; Rats, Long-Evans; Reaction Time; Reversal Learning; Spatial Behavior | 2008 |
Peripheral type benzodiazepine binding sites as a tool for the detection and quantification of CNS injury.
Topics: Animals; Autoradiography; Biomarkers; Brain Chemistry; Brain Injuries; Brain Ischemia; Carrier Proteins; Convulsants; Isoquinolines; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurotoxins; Protein Binding; Radioligand Assay; Rats; Receptors, GABA; Receptors, GABA-A | 2001 |
Traumatic brain injury-induced excitotoxicity assessed in a controlled cortical impact model.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Brain; Brain Injuries; Cerebral Cortex; Glutamates; Glutamic Acid; Glutamine; Male; Microdialysis; Microinjections; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Serine | 1993 |
Early evolution and recovery from excitotoxic injury in the neonatal rat brain: a study combining magnetic resonance imaging, electrical impedance, and histology.
Topics: Animals; Animals, Newborn; Brain; Brain Injuries; Dizocilpine Maleate; Electric Conductivity; Magnetic Resonance Imaging; N-Methylaspartate; Neurotoxins; Piperazines; Rats; Wound Healing | 1994 |
Comparison of diffusion-weighted MRI with changes in cell volume in a rat model of brain injury.
Topics: Animals; Brain; Brain Injuries; Cell Size; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Electric Impedance; Extracellular Space; Magnetic Resonance Imaging; N-Methylaspartate; Rats | 1994 |
Intracellular calcium dynamics and cerebral injury: modeling various insults in vitro.
Topics: Brain Injuries; Calcium; Cells, Cultured; Energy Metabolism; Glutamates; Glutamic Acid; Models, Neurological; N-Methylaspartate; Spinal Cord | 1993 |
Potentiation of N-methyl-D-aspartate-mediated brain injury by a human immunodeficiency virus-1-derived peptide in perinatal rodents.
Topics: AIDS Dementia Complex; Animals; Animals, Newborn; Brain Injuries; Disease Models, Animal; Gene Products, env; Gene Products, gag; Hippocampus; HIV-1; N-Methylaspartate; Rats; Recombinant Fusion Proteins | 1993 |
Traumatic brain damage prevented by the non-N-methyl-D-aspartate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo[f] quinoxaline.
Topics: Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Humans; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Piperazines; Quinoxalines; Rats; Rats, Inbred F344; Time Factors; Wounds, Nonpenetrating | 1996 |
Hemoglobin potentiates excitotoxic injury in cortical cell culture.
Topics: Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Antioxidants; Brain Injuries; Cells, Cultured; Cerebral Cortex; Chromans; Deferoxamine; Drug Synergism; Excitatory Amino Acids; Hemoglobin A; Humans; Kainic Acid; Kinetics; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neuroglia; Neurons | 1996 |
Adenovirus-mediated over-expression of interleukin-1 receptor antagonist reduces susceptibility to excitotoxic brain injury in perinatal rats.
Topics: Adenoviruses, Human; Animals; Animals, Newborn; beta-Galactosidase; Brain; Brain Injuries; Cerebral Ventricles; Corpus Striatum; Excitatory Amino Acid Antagonists; Genetic Vectors; Humans; Injections, Intraventricular; Interleukin 1 Receptor Antagonist Protein; Microinjections; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sialoglycoproteins | 1996 |
Reduction of voltage-dependent Mg2+ blockade of NMDA current in mechanically injured neurons.
Topics: Animals; Brain Injuries; Calcium; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Magnesium; Membrane Potentials; N-Methylaspartate; Naphthalenes; Neurons; Patch-Clamp Techniques; Protein Kinase C; Rats; Receptors, N-Methyl-D-Aspartate | 1996 |
Chronic, post-injury administration of D-cycloserine, an NMDA partial agonist, enhances cognitive performance following experimental brain injury.
Topics: Animals; Antimetabolites; Brain Injuries; Cognition; Cycloserine; Male; Maze Learning; N-Methylaspartate; Postural Balance; Rats; Rats, Sprague-Dawley | 1996 |
Disruption of spatial but not object-recognition memory by neurotoxic lesions of the dorsal hippocampus in rats.
Topics: Amnesia; Animals; Brain Injuries; Cerebral Cortex; Discrimination Learning; Disease Models, Animal; Excitatory Amino Acid Agonists; Hippocampus; Male; Maze Learning; Memory; N-Methylaspartate; Orientation; Pattern Recognition, Visual; Rats; Rats, Wistar; Temporal Lobe; Time Factors | 1997 |
Effects of moderate, central fluid percussion traumatic brain injury on nitric oxide synthase activity in rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Brain Injuries; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Excitatory Amino Acid Agonists; Ionomycin; Ionophores; Male; N-Methylaspartate; Nitric Oxide Synthase; Potassium Chloride; Rats; Rats, Sprague-Dawley | 1998 |
iNOS contribution to the NMDA-induced excitotoxic lesion in the rat striatum.
Topics: Animals; Brain Injuries; Corpus Striatum; Dexamethasone; Dizocilpine Maleate; Guanidines; Male; N-Methylaspartate; Neurotoxins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley | 1998 |
Excitotoxic brain injury stimulates expression of the chemokine receptor CCR5 in neonatal rats.
Topics: Animals; Animals, Newborn; Blotting, Western; Brain Injuries; Gene Expression; Hippocampus; HIV Envelope Protein gp120; HIV-1; Immunohistochemistry; In Situ Hybridization; Microglia; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, CCR5; RNA, Messenger | 1998 |
Distinct roles for sodium, chloride, and calcium in excitotoxic dendritic injury and recovery.
Topics: Animals; Brain Injuries; Bridged Bicyclo Compounds; Calcium; Cells, Cultured; Chlorides; Coculture Techniques; Cytosol; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Microscopy, Fluorescence; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Sodium; Veratridine | 1998 |
N-Methyl-D-aspartate antagonists and apoptotic cell death triggered by head trauma in developing rat brain.
Topics: Animals; Apoptosis; Brain; Brain Injuries; Caudate Nucleus; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Frontal Lobe; Gyrus Cinguli; In Situ Nick-End Labeling; N-Methylaspartate; Nerve Degeneration; Parietal Lobe; Piperazines; Rats; Rats, Wistar; Thalamus; Time Factors | 1999 |
Alterations in calcium-mediated signal transduction after traumatic injury of cortical neurons.
Topics: Animals; Brain Injuries; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; N-Methylaspartate; Neuroglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Thapsigargin | 1999 |
Inhibition of TNF-alpha can attenuate or exacerbate excitotoxic injury in neonatal rat brain.
Topics: Animals; Animals, Newborn; Atrophy; Brain; Brain Injuries; Carrier Proteins; Corpus Striatum; Disease Models, Animal; Drug Synergism; Excitatory Amino Acid Agonists; Hippocampus; Inflammation; N-Methylaspartate; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Tumor Necrosis Factor Decoy Receptors; Tumor Necrosis Factor-alpha | 2000 |
CP-101,606, an NR2B subunit selective NMDA receptor antagonist, inhibits NMDA and injury induced c-fos expression and cortical spreading depression in rodents.
Topics: Animals; Blotting, Northern; Brain Injuries; Cortical Spreading Depression; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; Genes, fos; Hippocampus; Immunohistochemistry; Male; Mice; N-Methylaspartate; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 2000 |
Optical light scatter imaging of cellular and sub-cellular morphology changes in stressed rat hippocampal slices.
Topics: Animals; Brain Injuries; Cells, Cultured; Excitatory Amino Acid Agonists; Hippocampus; Image Processing, Computer-Assisted; Microspheres; Mitochondrial Swelling; N-Methylaspartate; Neurons; Neurotoxins; Optics and Photonics; Rats; Rats, Sprague-Dawley; Scattering, Radiation | 2000 |
Neuronal, astroglial and microglial cytokine expression after an excitotoxic lesion in the immature rat brain.
Topics: Age Factors; Animals; Animals, Newborn; Astrocytes; Brain Injuries; Cytokines; Gene Expression Regulation, Developmental; Interleukin-1; Interleukin-6; Microglia; N-Methylaspartate; Neocortex; Nerve Degeneration; Neurons; Rats; Rats, Long-Evans; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2000 |
NOC/oFQ contributes to age-dependent impairment of NMDA-induced cerebrovasodilation after brain injury.
Topics: Aging; Animals; Animals, Newborn; Arterioles; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal; Excitatory Amino Acids; Female; Glutamic Acid; Male; N-Methylaspartate; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Opioid Peptides; Peptide Fragments; Pia Mater; Receptors, Opioid; Swine; Vasoconstriction; Vasodilation; Wounds, Nonpenetrating | 2000 |
Neuronal death enhanced by N-methyl-D-aspartate antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Injuries; Cell Death; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Piperazines; Propionates; Quinoxalines; Rats; Rats, Wistar; Wounds and Injuries | 2000 |
Diazepam modifies the effect of pedunculopontine lesions on morphine but not on amphetamine conditioned place preference.
Topics: Amphetamine; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Brain Injuries; Central Nervous System Stimulants; Conditioning, Psychological; Diazepam; Excitatory Amino Acid Agonists; Male; Maze Learning; Morphine; N-Methylaspartate; Narcotics; Rats; Rats, Long-Evans; Tegmentum Mesencephali | 2000 |
Monocyte chemoattractant protein-1 is a mediator of acute excitotoxic injury in neonatal rat brain.
Topics: Acute Disease; Animals; Animals, Newborn; Antibodies; Brain; Brain Injuries; Chemokine CCL2; Drug Interactions; Encephalitis; Female; Hippocampus; Male; N-Methylaspartate; Neostriatum; Neurotoxins; Rats; Rats, Sprague-Dawley | 2000 |
mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors.
Topics: Animals; Brain Injuries; Cell Survival; Cells, Cultured; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Hydrolysis; Male; Maze Learning; Memory; N-Methylaspartate; Neurons; Neuroprotective Agents; Phosphatidylinositols; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2001 |
Accumulation of the anandamide precursor and other N-acylethanolamine phospholipids in infant rat models of in vivo necrotic and apoptotic neuronal death.
Topics: Animals; Apoptosis; Arachidonic Acids; Brain Injuries; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Endocannabinoids; Ethanolamines; Male; N-Methylaspartate; Necrosis; Neurodegenerative Diseases; Neurons; Phospholipids; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Species Specificity; Wounds, Nonpenetrating | 2001 |
Age dependent endothelin contribution to NOC/oFQ induced impairment of NMDA cerebrovasodilation after brain injury.
Topics: Age Factors; Animals; Brain Injuries; Endothelin-1; N-Methylaspartate; Nociceptin; Opioid Peptides; Swine; Vasodilation; Vasodilator Agents | 2001 |
Subtle alterations in NMDA-stimulated cyclic GMP levels following lateral fluid percussion brain injury.
Topics: Animals; Brain Injuries; Cognition Disorders; Cyclic GMP; Disease Models, Animal; Functional Laterality; Hippocampus; Male; N-Methylaspartate; Percussion; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 2001 |
Age-Dependent vasopressinergic modulation of Noc/oFQ-induced impairment of NMDA cerebrovasodilation after brain injury.
Topics: Aging; Animals; Animals, Newborn; Blood Gas Analysis; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Excitatory Amino Acid Agonists; Female; Male; N-Methylaspartate; Nociceptin; Opioid Peptides; Receptors, N-Methyl-D-Aspartate; Swine; Vasodilation; Vasodilator Agents; Vasopressins | 2001 |
The conjoint importance of the hippocampus and anterior thalamic nuclei for allocentric spatial learning: evidence from a disconnection study in the rat.
Topics: Animals; Anterior Thalamic Nuclei; Behavior, Animal; Brain Injuries; Functional Laterality; Hippocampus; Male; Maze Learning; Memory; Microinjections; N-Methylaspartate; Nerve Net; Rats; Space Perception | 2001 |
Astrocytic factors protect neuronal integrity and reduce microglial activation in an in vitro model of N-methyl-D-aspartate-induced excitotoxic injury in organotypic hippocampal slice cultures.
Topics: Animals; Astrocytes; Brain Injuries; Cell Communication; Cell Death; Cell Size; Cells, Cultured; Culture Media, Conditioned; Dentate Gyrus; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Agonists; Fluorescein-5-isothiocyanate; Gliosis; Growth Substances; Hippocampus; Lectins; Microglia; Microscopy, Confocal; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Wistar; Transforming Growth Factor beta | 2001 |
The systemic and local acute phase response following acute brain injury.
Topics: Acute Disease; Acute-Phase Proteins; Animals; Brain; Brain Injuries; DNA Primers; Female; Gene Expression Regulation; Interleukin-1; Liver; Mice; Mice, Inbred C57BL; N-Methylaspartate; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic | 2002 |
Glial expression of small heat shock proteins following an excitotoxic lesion in the immature rat brain.
Topics: Aging; Animals; Astrocytes; Brain; Brain Injuries; Cerebral Cortex; Female; Glial Fibrillary Acidic Protein; Gliosis; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; HSP27 Heat-Shock Proteins; HSP47 Heat-Shock Proteins; Macrophages; Male; Microglia; N-Methylaspartate; Neoplasm Proteins; Nerve Degeneration; Neuroglia; Rats; Rats, Long-Evans; Stress, Physiological; Thalamus; Up-Regulation | 2002 |
Pretreatment with NMDA antagonists limits release of excitatory amino acids following traumatic brain injury.
Topics: Amino Acids; Animals; Brain Injuries; Chromatography, High Pressure Liquid; Dextrorphan; Dialysis; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Susceptibility of brain to AMPA induced excitotoxicity transiently peaks during early postnatal development.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Brain; Brain Injuries; Diazepam; Dizocilpine Maleate; Female; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Organ Specificity; Phenytoin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Seizures | 1992 |
The severity of excitotoxic brain injury is dependent on brain temperature in immature rat.
Topics: Animals; Animals, Newborn; Body Temperature; Brain; Brain Injuries; Female; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Temperature | 1991 |
The role of excitatory amino acids and NMDA receptors in traumatic brain injury.
Topics: Animals; Aspartic Acid; Binding, Competitive; Brain; Brain Injuries; Dextrorphan; Glutamates; Glutamic Acid; Magnesium; Magnetic Resonance Spectroscopy; Male; N-Methylaspartate; Phosphates; Phosphocreatine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |