Page last updated: 2024-08-22

n-methylaspartate and Brain Diseases

n-methylaspartate has been researched along with Brain Diseases in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (8.33)	18.7374
1990's	28 (46.67)	18.2507
2000's	20 (33.33)	29.6817
2010's	6 (10.00)	24.3611
2020's	1 (1.67)	2.80

Authors

Authors	Studies
Bausch, AE; Bischof, H; Ehinger, R; Frank, N; Kabagema-Bilan, C; Kuret, A; Lukowski, R; Malli, R; Matt, L; Ruth, P; Wild, K	1
Hosseini-Zare, MS; Hübel, N; Ullah, G; Žiburkus, J	1
Alcon, C; Altafaj, X; Armstrong, J; Bayés, À; Chu-Van, E; Ciruela, F; Colsch, B; Fernández-Dueñas, V; García-Cazorla, À; García-Díaz, R; Gasull, X; Gómez de Salazar, M; Gratacòs-Batlle, E; Grau, C; Locubiche, S; López-Sala, A; Olivella, M; Ramos-Vicente, D; Santos-Gómez, A; Sindreu, C; Soto, D	1
Cheon, Y; Igarashi, M; Keleshian, VL; Kellom, M; Kim, HW; Rao, JS; Rapoport, SI; Taha, AY	1
Fu, Q; Liu, X; Wang, Y; Zhao, S	1
Chara, JC; Cipriani, R; Matute, C; Rodríguez-Antigüedad, A	1
Baud, O; Destot-Wong, KD; Favrais, G; Gressens, P; Gupta, SK; Lelièvre, V; Liang, K; Mani, S; Pansiot, J; Schwendimann, L; Spedding, M	1
Acarin, L; Arís, A; Beyaert, R; Gonzalez, B; Gonzalez, P; Peluffo, H; Villaverde, A	1
Fanselow, MS; Morrison, GE; Oommen, SS; Quinn, JJ	1
Bohn, I; Giertler, C; Hauber, W	1
Wallace, DG; Whishaw, IQ	1
Feldon, J; Lacroix, L; Salazar, RF; White, IM; White, W	1
Chai, SC; White, NM	1
Allen, K; Dore, FY; Goulet, S; Potvin, O	1
Andrade, JP; Lukoyanov, NV; Lukoyanova, EA; Paula-Barbosa, MM	1
Fanselow, MS; Fendt, M; Koch, M	1
Lecluse, V; Lehmann, H; Mumby, DG; Tremblay, A	1
Martin, GM; Skinner, DM; Stringer, KG	1
Acarin, L; Arís, A; Castellano, B; González, B; González, P; Peluffo, H; Villaverde, A	1
Allen, K; Doré, FY; Goulet, S; Potvin, O; Thibaudeau, G	1
Anrather, J; Iadecola, C; Kawano, T; Kunz, A; Orio, M; Zhou, P	1
Maren, S; McLachlan, IG; Rabinak, CA; Zimmerman, JM	1
Abraini, JH; Alix, P; Haelewyn, B; Maubert, E	1
Burnet, M; Groebe, K; Klemm, M; Poznanović, S; Proikas-Cezanne, T; Schoepf, R; Schrattenholz, A; Schwall, GP; Soskić, V; Stegmann, W; Zengerling, H	1
Greenamyre, JT; Greene, JG	1
Cotman, CW; Kesslak, JP; Miller, S; Romano, C	1
Lehmann, JC; Procureur, D; Wood, PL	1
Evrard, P; Gadisseux, JF; Gressens, P; Marret, S; Mukendi, R	1
Boldry, RC; Chase, TN; Engber, TM	1
Lipton, SA; Rosenberg, PA	1
Kondoh, T; Low, WC	1
Balázs, R; Berkelbach van der Sprenkel, JW; Nicolay, K; Tulleken, CA; van Lookeren Campagne, M; Verheul, HB	1
Arban, R; Fadda, E; Lipartiti, M; Manev, H; Sautter, J; Savoini, G; Siliprandi, R	1
Burtrum, D; Silverstein, FS	1
Johnston, MV; Taylor, GA; Traystman, RJ; Trescher, WH	1
Dijkhuizen, RM; Dreher, W; Hoehn-Berlage, M; Hossmann, KA; Leibfritz, D; Nicolay, K; Niendorf, T; Tulleken, CA; van der Toorn, A; van Lookeren Campagne, M; Verheul, HB	1
Barnewolt, CE; Dunning, PS; Taylor, GA	1
de Graaf, RA; Dijkhuizen, RM; Nicolay, K; Tulleken, KA	1
Gupta, R; Nadimpalli, R; Nath, R; Scott, M; Wang, KK	1
Diestel, A; Eyüpoglu, IY; Nitsch, R; Ullrich, O	1
Changeux, JP; Evrard, P; Gressens, P; Laudenbach, V; Medja, F; Rossi, FM; Zoli, M	1
Buchan, AM	1
Albers, GW; Choi, DW; Goldberg, MP	1
Hachinski, V	1
Borosky, SA; Clissold, DB; Ferkany, JW; Goode, S; Karbon, EW; Patch, RJ; Pontecorvo, MJ	1
Clark, AJ; Hastings, MH; Latimer, M; Stone, TW; Winn, P	1
Araki, N; Greenberg, JH; Reivich, M; Uematsu, D	1
Althaus, JS; Hudson, CJ; Means, ED; Scherch, HM; Von Voigtlander, PF	1
Fletcher, PJ; Kish, SJ; Wilson, JM	1
Lazzaro, A; Leon, A; Lipartiti, M; Mazzari, S; Toffano, G; Zanoni, R	1
Choi, DW	1
Johnston, MV; McDonald, JW	1
Susel, Z	1
Attwell, D; Barbour, B; Szatkowski, M	1
Chernack, J; Cornfeldt, ML; Fielding, S; Martin, LL; Payack, JF; Ramirez, V; Rudolphi, KA; Rush, DK; Wilker, JC; Wilmot, CA	1
Simon, RP	1
Johnston, MV; McDonald, JW; Silverstein, FS; Uckele, J	1
Johnston, MV; McDonald, JW; Roeser, NF; Silverstein, FS	1
Meldrum, B; Schwarcz, R	1
Beart, PM; Christie, MJ; Jarrott, B; Maccarrone, C	1

Reviews

7 review(s) available for n-methylaspartate and Brain Diseases

Article	Year
Roles of metabotropic glutamate receptors in brain plasticity and pathology. Annals of the New York Academy of Sciences, 1995, May-10, Volume: 757 Topics: Animals; Astrocytes; Brain; Brain Diseases; Carbachol; Cells, Cultured; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; In Vitro Techniques; Mice; N-Methylaspartate; Neuronal Plasticity; Phosphatidylinositols; Receptors, Metabotropic Glutamate; Signal Transduction	1995
Excitatory amino acids as a final common pathway for neurologic disorders. The New England journal of medicine, 1994, Mar-03, Volume: 330, Issue:9 Topics: Biological Transport; Brain Diseases; Calcium; Glutamates; Glutamic Acid; Humans; N-Methylaspartate; Neurons; Receptors, Glutamate	1994
Do NMDA antagonists prevent neuronal injury? No. Archives of neurology, 1992, Volume: 49, Issue:4 Topics: Animals; Brain; Brain Diseases; Brain Ischemia; Cell Death; Glutamates; Glutamic Acid; Hypoxia, Brain; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate	1992
Do NMDA antagonists prevent neuronal injury? Yes. Archives of neurology, 1992, Volume: 49, Issue:4 Topics: Animals; Brain; Brain Diseases; Brain Ischemia; Cell Death; Hypoxia, Brain; N-Methylaspartate; Neurons	1992
Cerebral hypoxia: some new approaches and unanswered questions. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:8 Topics: Animals; Aspartic Acid; Brain Diseases; Cell Survival; Cerebrovascular Circulation; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Hypoxia; N-Methylaspartate; Neuroglia; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1990
[Excitatory amino acid and their involvement in pathological processes in the brain]. Harefuah, 1990, Mar-15, Volume: 118, Issue:6 Topics: Animals; Aspartic Acid; Brain Diseases; gamma-Aminobutyric Acid; Humans; N-Methylaspartate	1990
Role of endogenous excitatory amino acid neurotransmitters in the pathogenesis and evolution of acute brain injury. The Pediatric infectious disease journal, 1989, Volume: 8, Issue:12 Topics: Acute Disease; Amino Acids; Animals; Aspartic Acid; Brain Diseases; Brain Injuries; Calcium; Calcium Channels; Humans; Meningitis; N-Methylaspartate; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1989

Other Studies

53 other study(ies) available for n-methylaspartate and Brain Diseases

Article	Year
Slack K FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:5 Topics: Action Potentials; Animals; Brain Diseases; Cell Death; Cells, Cultured; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Potassium Channels, Sodium-Activated; Signal Transduction	2021
The role of glutamate in neuronal ion homeostasis: A case study of spreading depolarization. PLoS computational biology, 2017, Volume: 13, Issue:10 Topics: Animals; Aspartic Acid; Astrocytes; Brain Diseases; Cell Size; Computational Biology; Electrophysiological Phenomena; Glutamic Acid; Homeostasis; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Models, Neurological; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Visual Cortex	2017
L-Serine dietary supplementation is associated with clinical improvement of loss-of-function Science signaling, 2019, 06-18, Volume: 12, Issue:586 Topics: Animals; Brain Diseases; Child; Cognition; Dietary Supplements; Humans; Loss of Function Mutation; Male; Mice; Models, Molecular; Motor Activity; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Rett Syndrome; Serine	2019
Neuropathological responses to chronic NMDA in rats are worsened by dietary n-3 PUFA deprivation but are not ameliorated by fish oil supplementation. PloS one, 2014, Volume: 9, Issue:5 Topics: Animals; Brain Chemistry; Brain Diseases; Chronic Disease; Dietary Fats; Excitatory Amino Acid Agonists; Fatty Acids, Omega-3; Group IV Phospholipases A2; Interleukin-1beta; Lipid Metabolism; Male; N-Methylaspartate; Nerve Growth Factor; Rats	2014
Effects of the medial or basolateral amygdala upon social anxiety and social recognition in mice. Turkish journal of medical sciences, 2014, Volume: 44, Issue:3 Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Brain Diseases; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Recognition, Psychology	2014
FTY720 attenuates excitotoxicity and neuroinflammation. Journal of neuroinflammation, 2015, May-08, Volume: 12 Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Brain Diseases; Cell Death; Cells, Cultured; Cerebellum; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Fingolimod Hydrochloride; In Vitro Techniques; Kainic Acid; L-Lactate Dehydrogenase (Cytochrome); Male; N-Methylaspartate; Neurons; Organ Culture Techniques; Phosphorylation; Rats; Rats, Sprague-Dawley; Time Factors	2015
The AMPA receptor positive allosteric modulator, S18986, is neuroprotective against neonatal excitotoxic and inflammatory brain damage through BDNF synthesis. Neuropharmacology, 2009, Volume: 57, Issue:3 Topics: Animals; Animals, Newborn; Apoptosis; Benzothiadiazines; Brain; Brain Diseases; Brain-Derived Neurotrophic Factor; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Female; Male; Mice; N-Methylaspartate; Necrosis; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Time Factors	2009
Overexpression of the nuclear factor kappaB inhibitor A20 is neurotoxic after an excitotoxic injury to the immature rat brain. Neurological research, 2013, Volume: 35, Issue:3 Topics: Animals; Astrocytes; Brain Diseases; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; DNA-Binding Proteins; Excitatory Amino Acid Agonists; Immunohistochemistry; N-Methylaspartate; Neurons; NF-kappa B; Rats; Rats, Long-Evans; Rats, Transgenic; Tumor Necrosis Factor alpha-Induced Protein 3; Up-Regulation	2013
Post-training excitotoxic lesions of the dorsal hippocampus attenuate forward trace, backward trace, and delay fear conditioning in a temporally specific manner. Hippocampus, 2002, Volume: 12, Issue:4 Topics: Animals; Brain Diseases; Conditioning, Psychological; Excitatory Amino Acid Agonists; Fear; Hippocampus; Male; N-Methylaspartate; Rats; Rats, Long-Evans; Reaction Time	2002
Orbital prefrontal cortex and guidance of instrumental behaviour in rats under reversal conditions. Behavioural brain research, 2003, Jul-14, Volume: 143, Issue:1 Topics: Adaptation, Physiological; Analysis of Variance; Animals; Brain Diseases; Conditioning, Operant; Discrimination, Psychological; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reaction Time; Reinforcement, Psychology; Reversal Learning	2003
NMDA lesions of Ammon's horn and the dentate gyrus disrupt the direct and temporally paced homing displayed by rats exploring a novel environment: evidence for a role of the hippocampus in dead reckoning. The European journal of neuroscience, 2003, Volume: 18, Issue:3 Topics: Animals; Biomechanical Phenomena; Brain Diseases; Dentate Gyrus; Environment; Excitatory Amino Acid Agonists; Exploratory Behavior; Female; Hippocampus; Homing Behavior; Motor Activity; N-Methylaspartate; Rats; Rats, Long-Evans; Smell; Space Perception; Time Factors; Touch	2003
NMDA lesions in the medial prefrontal cortex impair the ability to inhibit responses during reversal of a simple spatial discrimination. Behavioural brain research, 2004, Jul-09, Volume: 152, Issue:2 Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Diseases; Discrimination Learning; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Neural Inhibition; Prefrontal Cortex; Rats; Reversal Learning; Space Perception; Time Factors	2004
Effects of fimbria-fornix, hippocampus, and amygdala lesions on discrimination between proximal locations. Behavioral neuroscience, 2004, Volume: 118, Issue:4 Topics: Amygdala; Animals; Brain Diseases; Choice Behavior; Conditioning, Psychological; Cues; Discrimination Learning; Fornix, Brain; Hippocampus; Limbic System; Maze Learning; N-Methylaspartate; Neurotoxins; Rats; Rats, Long-Evans; Reaction Time; Reinforcement, Psychology; Space Perception	2004
Modulation of the impairment of hippocampectomized rats on the radial-arm maze cue task by visual characteristics and subicular damage. Behavioral neuroscience, 2004, Volume: 118, Issue:6 Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Diseases; Cues; Excitatory Amino Acid Agonists; Hippocampus; Male; Maze Learning; N-Methylaspartate; Random Allocation; Rats; Rats, Long-Evans; Space Perception; Spatial Behavior	2004
Impaired water maze navigation of Wistar rats with retrosplenial cortex lesions: effect of nonspatial pretraining. Behavioural brain research, 2005, Mar-07, Volume: 158, Issue:1 Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Diseases; Excitatory Amino Acid Agonists; Functional Laterality; Gyrus Cinguli; Male; Maze Learning; Memory; N-Methylaspartate; Rats; Rats, Wistar; Spatial Behavior; Swimming	2005
Lesions of the dorsal hippocampus block trace fear conditioned potentiation of startle. Behavioral neuroscience, 2005, Volume: 119, Issue:3 Topics: Acoustic Stimulation; Analysis of Variance; Animals; Behavior, Animal; Brain Diseases; Conditioning, Psychological; Fear; Hippocampus; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Reflex, Startle; Time Factors	2005
Hippocampal damage and anterograde object-recognition in rats after long retention intervals. Hippocampus, 2005, Volume: 15, Issue:8 Topics: Amnesia, Anterograde; Animals; Brain Diseases; Exploratory Behavior; Hippocampus; Learning; Male; N-Methylaspartate; Rats; Rats, Long-Evans; Recognition, Psychology; Retention, Psychology; Task Performance and Analysis; Time Factors	2005
The effects of hippocampal lesions on response, direction, and place learning in rats. Behavioral neuroscience, 2005, Volume: 119, Issue:4 Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Diseases; Cues; Hippocampus; Male; Maze Learning; N-Methylaspartate; Rats; Rats, Long-Evans; Space Perception; Spatial Behavior	2005
Neuroprotection from NMDA excitotoxic lesion by Cu/Zn superoxide dismutase gene delivery to the postnatal rat brain by a modular protein vector. BMC neuroscience, 2006, Apr-25, Volume: 7 Topics: Animals; Animals, Newborn; Brain; Brain Diseases; Cell Death; Female; Gene Expression; Gene Transfer Techniques; Genetic Vectors; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Long-Evans; Superoxide Dismutase; Transgenes; Tyrosine	2006
Dorsal, ventral, and complete excitotoxic lesions of the hippocampus in rats failed to impair appetitive trace conditioning. Behavioural brain research, 2007, Dec-11, Volume: 185, Issue:1 Topics: Analysis of Variance; Animals; Appetite; Brain Diseases; Conditioning, Classical; Excitatory Amino Acid Agonists; Hippocampus; Male; N-Methylaspartate; Psychomotor Performance; Rats; Rats, Long-Evans; Water Deprivation	2007
Lipopolysaccharide induces early tolerance to excitotoxicity via nitric oxide and cGMP. Stroke, 2007, Volume: 38, Issue:10 Topics: Animals; Anisomycin; Brain Diseases; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Guanylate Cyclase; Ischemic Preconditioning; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxadiazoles; Protein Synthesis Inhibitors; Quinoxalines	2007
The central nucleus of the amygdala is essential for acquiring and expressing conditional fear after overtraining. Learning & memory (Cold Spring Harbor, N.Y.), 2007, Volume: 14, Issue:9 Topics: Acoustic Stimulation; Amygdala; Animals; Behavior, Animal; Brain Diseases; Conditioning, Classical; Electroshock; Fear; Injections; Male; Memory; Muscimol; N-Methylaspartate; Neurotoxins; Rats; Rats, Long-Evans	2007
NMDA-induced striatal brain damage and time-dependence reliability of thionin staining in rats. Journal of neuroscience methods, 2008, Mar-15, Volume: 168, Issue:2 Topics: Animals; Brain Diseases; Cell Death; Coloring Agents; Excitatory Amino Acid Agonists; Immunohistochemistry; Male; Microinjections; N-Methylaspartate; Neostriatum; Neurons; Phenothiazines; Rats; Rats, Sprague-Dawley	2008
A connection between the mitochondrial permeability transition pore, autophagy, and cerebral amyloidogenesis. Journal of proteome research, 2008, Volume: 7, Issue:6 Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Apoptosis; Autophagy; Azasteroids; Brain Diseases; Disease Models, Animal; Dutasteride; Enzyme Inhibitors; Finasteride; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondrial ADP, ATP Translocases; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; N-Methylaspartate; Neocortex; Neurons; Neuroprotective Agents; Plaque, Amyloid; Potassium Cyanide; Presenilins; Sex Factors; Testosterone	2008
Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate. Journal of neurochemistry, 1995, Volume: 64, Issue:5 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Diseases; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Male; Malonates; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Succinate Dehydrogenase	1995
7-Chlorokynurenate prevents NMDA-induced and kainate-induced striatal lesions. Brain research, 1993, Aug-20, Volume: 620, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Diseases; Choline O-Acetyltransferase; Corpus Striatum; Dose-Response Relationship, Drug; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine	1993
Effect of ibotenate on brain development: an excitotoxic mouse model of microgyria and posthypoxic-like lesions. Journal of neuropathology and experimental neurology, 1995, Volume: 54, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Alanine; Amino Acids; Animals; Brain; Brain Diseases; Embryonic and Fetal Development; Excitatory Amino Acids; Female; Glial Fibrillary Acidic Protein; Hypoxia; Ibotenic Acid; Male; Mice; N-Methylaspartate; Neurons; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate	1995
Influence of previous exposure to levodopa on the interaction between dizocilpine and dopamine D1 and D2 agonists in rats with 6-hydroxydopamine-induced lesions. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Brain Diseases; Dizocilpine Maleate; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Levodopa; Male; Motor Activity; N-Methylaspartate; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2	1993
Glutamate uptake blockade induces striatal dopamine release in 6-hydroxydopamine rats with intrastriatal grafts: evidence for host modulation of transplanted dopamine neurons. Experimental neurology, 1994, Volume: 127, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Diseases; Brain Tissue Transplantation; Corpus Striatum; Dopamine; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kainic Acid; Male; Mesencephalon; N-Methylaspartate; Neurons; Oxidopamine; Rats; Tyrosine 3-Monooxygenase	1994
Temporal evolution of NMDA-induced excitoxicity in the neonatal rat brain measured with 1H nuclear magnetic resonance imaging. Brain research, 1993, Aug-06, Volume: 618, Issue:2 Topics: Animals; Animals, Newborn; Brain Diseases; Corpus Striatum; Diffusion; Dizocilpine Maleate; Histocytochemistry; Magnetic Resonance Spectroscopy; Microinjections; N-Methylaspartate; Necrosis; Rats	1993
In rats, the metabotropic glutamate receptor-triggered hippocampal neuronal damage is strain-dependent. Life sciences, 1993, Volume: 52, Issue:10 Topics: Animals; Behavior, Animal; Brain Diseases; Cycloleucine; Drug Synergism; Hippocampus; Male; N-Methylaspartate; Neurons; Neurotoxins; Rats; Rats, Inbred BN; Rats, Inbred F344; Rats, Inbred Strains; Rats, Sprague-Dawley; Receptors, Glutamate	1993
Excitotoxic injury stimulates glial fibrillary acidic protein mRNA expression in perinatal rat brain. Experimental neurology, 1993, Volume: 121, Issue:1 Topics: Animals; Brain Diseases; Dizocilpine Maleate; Glial Fibrillary Acidic Protein; In Situ Hybridization; N-Methylaspartate; Rats	1993
Experimental neuronal injury in the newborn lamb: a comparison of N-methyl-D-aspartic acid receptor blockade and nitric oxide synthesis inhibition on lesion size and cerebral hyperemia. Pediatric research, 1995, Volume: 38, Issue:5 Topics: Animals; Animals, Newborn; Arginine; Brain Diseases; Cattle; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hemodynamics; Hyperemia; N-Methylaspartate; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; Sheep	1995
Status of the neonatal rat brain after NMDA-induced excitotoxic injury as measured by MRI, MRS and metabolic imaging. NMR in biomedicine, 1996, Volume: 9, Issue:2 Topics: Animals; Brain Diseases; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fluoroscopy; Luminescent Measurements; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; N-Methylaspartate; Phosphorus; Rats; Rats, Wistar	1996
Excitotoxin-induced cerebral hyperemia in newborn piglets: regional cerebral blood flow mapping with contrast-enhanced power Doppler US. Radiology, 1998, Volume: 208, Issue:1 Topics: Animals; Animals, Newborn; Area Under Curve; Basal Ganglia; Blood Pressure; Brain Diseases; Brain Ischemia; Carbon Dioxide; Cerebrovascular Circulation; Contrast Media; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Agonists; Feasibility Studies; Fluorocarbons; Hyperemia; Hypoxia, Brain; Image Enhancement; Injections; Injections, Intravenous; N-Methylaspartate; Swine; Time Factors; Ultrasonography, Doppler; Vasodilator Agents	1998
Changes in the diffusion of water and intracellular metabolites after excitotoxic injury and global ischemia in neonatal rat brain. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1999, Volume: 19, Issue:3 Topics: Animals; Animals, Newborn; Body Water; Brain Diseases; Brain Ischemia; Diffusion; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Intracellular Fluid; N-Methylaspartate; Rats; Rats, Wistar	1999
Activation of apoptosis-linked caspase(s) in NMDA-injured brains in neonatal rats. Neurochemistry international, 2000, Volume: 36, Issue:2 Topics: Animals; Animals, Newborn; Apoptosis; Brain; Brain Diseases; Caspase 3; Caspase Inhibitors; Caspases; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; In Situ Nick-End Labeling; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Spectrin	2000
Regulation of microglial expression of integrins by poly(ADP-ribose) polymerase-1. Nature cell biology, 2001, Volume: 3, Issue:12 Topics: Animals; Brain Diseases; Cell Movement; Cells, Cultured; DNA, Antisense; Excitatory Amino Acid Agonists; Gene Expression; Lymphocyte Function-Associated Antigen-1; Mice; Microglia; N-Methylaspartate; Nerve Degeneration; Neurotoxins; NF-kappa B; Phagocytosis; Poly(ADP-ribose) Polymerases; RNA, Messenger; Transfection	2001
Selective activation of central subtypes of the nicotinic acetylcholine receptor has opposite effects on neonatal excitotoxic brain injuries. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:3 Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Autoradiography; Brain Diseases; Cell Death; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Ibotenic Acid; Injections; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; N-Methylaspartate; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Receptors, Nicotinic	2002
NMDA antagonist protection from neuronal injury. Archives of neurology, 1992, Volume: 49, Issue:4 Topics: Brain; Brain Diseases; Cell Death; N-Methylaspartate; Neurons	1992
Possible cerebroprotective and in vivo NMDA antagonist activities of sigma agents. Brain research bulletin, 1991, Volume: 26, Issue:3 Topics: Animals; Anticonvulsants; Brain Diseases; Electroshock; Haloperidol; Hypoxia; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nimodipine; Piperidines; Postural Balance; Pyrimidines; Receptors, Opioid; Receptors, sigma; Seizures	1991
A comparison of excitotoxic lesions of the basal forebrain by kainate, quinolinate, ibotenate, N-methyl-D-aspartate or quisqualate, and the effects on toxicity of 2-amino-5-phosphonovaleric acid and kynurenic acid in the rat. British journal of pharmacology, 1991, Volume: 102, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Diseases; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats	1991
Mechanism underlying protective effect of MK-801 against NMDA-induced neuronal injury in vivo. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1991, Volume: 11, Issue:5 Topics: Animals; Brain Diseases; Calcium; Cats; Cerebral Cortex; Cytosol; Dizocilpine Maleate; Ion Channels; Male; N-Methylaspartate; NAD; Neurons; Receptors, N-Methyl-D-Aspartate	1991
The kappa opioid-related anticonvulsants U-50488H and U-54494A attenuate N-methyl-D-aspartate induced brain injury in the neonatal rat. Brain research, 1991, Nov-15, Volume: 564, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Animals, Newborn; Brain; Brain Diseases; Diuresis; Dose-Response Relationship, Drug; N-Methylaspartate; Organ Size; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Staining and Labeling	1991
The polyamine synthesis inhibitor alpha-difluoromethylornithine is neuroprotective against N-methyl-D-aspartate-induced brain damage in vivo. European journal of pharmacology, 1991, Dec-10, Volume: 209, Issue:1-2 Topics: Animals; Biogenic Polyamines; Brain; Brain Diseases; Eflornithine; Models, Biological; N-Methylaspartate; Rats	1991
Monosialoganglioside GM1 reduces NMDA neurotoxicity in neonatal rat brain. Experimental neurology, 1991, Volume: 113, Issue:3 Topics: Animals; Animals, Newborn; Brain; Brain Diseases; Female; G(M1) Ganglioside; Male; N-Methylaspartate; Rats; Rats, Inbred Strains	1991
Pharmacology of N-methyl-D-aspartate-induced brain injury in an in vivo perinatal rat model. Synapse (New York, N.Y.), 1990, Volume: 6, Issue:2 Topics: Animals; Animals, Newborn; Anticonvulsants; Brain Diseases; Female; Glycine; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma	1990
Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake. Nature, 1990, Nov-29, Volume: 348, Issue:6300 Topics: Animals; Biological Transport, Active; Brain Diseases; Extracellular Space; Glutamates; Hypoxia; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neuroglia; Neurons; Potassium; Urodela	1990
Preclinical anticonvulsant and neuroprotective profile of 8319, a non-competitive NMDA antagonist. Progress in clinical and biological research, 1990, Volume: 361 Topics: Aniline Compounds; Animals; Anticonvulsants; Binding, Competitive; Brain Diseases; Brain Ischemia; Dizocilpine Maleate; Gerbillinae; Hippocampus; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Rats; Rats, Inbred Strains; Thiophenes; Tritium	1990
HA-966 (1-hydroxy-3-aminopyrrolidone-2) selectively reduces N-methyl-D-aspartate (NMDA)-mediated brain damage. Neuroscience letters, 1989, Sep-25, Volume: 104, Issue:1-2 Topics: Animals; Animals, Newborn; Aspartic Acid; Brain Diseases; Corpus Striatum; N-Methylaspartate; Oxadiazoles; Pyrrolidinones; Quisqualic Acid; Rats; Rats, Inbred Strains	1989
Quantitative assessment of neuroprotection against NMDA-induced brain injury. Experimental neurology, 1989, Volume: 106, Issue:3 Topics: Animals; Aspartic Acid; Brain; Brain Diseases; Choline O-Acetyltransferase; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Ketamine; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Regression Analysis	1989
Excitatory aminoacid antagonists provide a therapeutic approach to neurological disorders. Lancet (London, England), 1985, Jul-20, Volume: 2, Issue:8447 Topics: Adult; Amino Acids; Animals; Aspartic Acid; Brain Diseases; Brain Ischemia; Glutamates; Humans; Hypoxia, Brain; Infant; N-Methylaspartate; Nerve Degeneration; Neurotransmitter Agents; Quinolinic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Seizures	1985
Distribution of neuropeptide Y immunoreactivity in the rat basal ganglia: effects of excitotoxin lesions to caudate-putamen. Neuroscience letters, 1986, Jan-30, Volume: 63, Issue:3 Topics: Animals; Aspartic Acid; Basal Ganglia; Brain Diseases; Caudate Nucleus; Male; N-Methylaspartate; Nerve Tissue Proteins; Neuropeptide Y; Putamen; Radioimmunoassay; Rats; Rats, Inbred Strains; Tissue Distribution	1986