Page last updated: 2024-08-22

n-methylaspartate and Aura

n-methylaspartate has been researched along with Aura in 129 studies

Research

Studies (129)

TimeframeStudies, this research(%)All Research%
pre-199014 (10.85)18.7374
1990's59 (45.74)18.2507
2000's32 (24.81)29.6817
2010's16 (12.40)24.3611
2020's8 (6.20)2.80

Authors

AuthorsStudies
Banka, S; Basu, H; Blakes, AJM; English, J1
Bedinger, LA; Bilinovich, SM; Bupp, CP; Campbell, DB; Charron, JG; Devries, S; Hernandez, A; Prokop, JW; Seaver, LH; Vogt, DL; Williams, M1
Hložek, T; Kubová, H; Mareš, P; Páleníček, T; Uttl, L1
Badawi, M; Guo, Q; Mori, T; Pang, B; Shirai, Y; Suzuki-Kouyama, E; Tabuchi, K; Yanagawa, T; Zhou, M1
Alami, M; Brion, JD; Chiron, C; Dossi, E; Dulac, O; Galvani, G; Gataullina, S; Huberfeld, G; Laschet, J; Lemaire, É; Messaoudi, S; Nous, C; Touchet, S1
Kim, EJ; Kim, K; Kim, MJ; Lee, M; Yeom, J; Yum, MS1
Barzasi, M; Biamino, E; Brusco, A; Bruselles, A; Buxbaum, JD; Cardaropoli, S; Chand, P; Chiantia, G; Cipriani, V; Costa, A; De Rubeis, S; Di Luca, M; Eberini, I; Efthymiou, S; Ferrero, GB; Gardoni, F; Giustetto, M; Gurgone, A; Hiatt, SM; Kaiyrzhanov, R; Kelley, WV; Marcantoni, A; Palazzolo, L; Pavinato, L; Sisodiya, SM; Smedley, D; Spada, M; Stanic, J; Tartaglia, M; Vestito, L1
Kim, EJ; Kim, MJ; Ko, TS; Lee, M; Woo, DC; Yum, MS1
Kishore, DV; Prasad, NBL; Shylaja, H; Venkataranganna, MV; Viswanatha, GL1
Baldassarri, M; Della Chiara, V; Fallerini, C; Frullanti, E; Gamucci, A; Mancardi, MM; Mari, F; Papa, FT; Renieri, A; Veneselli, E; Zalba-Jadraque, L1
Bienvenu, T; Dulac, O; Gataullina, S; Huberfeld, G; Nabbout, R1
Mctague, A1
Godlevsky, LS; Godovan, VV; Kresyun, VI; Polyasny, VA1
Belardinelli, L; George, AL; Hirakawa, R; Kahlig, KM; Liu, L; Rajamani, S1
Ammassari-Teule, M; Bagetta, V; Calabresi, P; Costa, C; Fejtova, A; Ghiglieri, V; Gundelfinger, ED; Morelli, E; Pendolino, V; Picconi, B; Pignataro, A1
Deisenhammer, F; Dietmann, A; Friedrich, K; Griesmacher, A; JilekAall, L; König, R; Matuja, W; Pfausler, B; Schmutzhard, E; Seger, C; Wallner, B; Winkler, AS1
Kato, F; Takahashi, Y; Tsuji, M; Watabe, AM1
Itoh, H; Nagayoshi, A; Oku, N; Takeda, A1
Bailabar, T; Bum, EN; Hiana, IR; Moto, FC; Nkainsa, LA; Rakotonirina, A; Rakotonirina, SV; Seke Etet, PF; Seyni, P; Taiwe, GS1
Che, H; Gao, B; Li, J; Ma, J; Shao, Z; Wang, W; Wang, Z; Zhang, W1
Baldwin, RA; Jäger, AK; Niquet, J; Pedersen, ME; Stafford, GI; van Staden, J; Wasterlain, CG1
Rossetti, AO; Seeck, M; Zacharia, A1
Dwyer, J; Frim, D; Koch, H; Kohrman, M; Martell, A; Ramirez, JM; van Drongelen, W; Zanella, S1
Chevalier, M; Doren, EL; Frim, DM; Koch, H; Kohrman, MH; Lasky, RE; Lew, SM; Marcuccilli, CJ; Mrejeru, A; Peña-Ortega, F; Pytel, P; Ramirez, JM; Tryba, AK; van Drongelen, W; Viemari, JC1
Kaptsov, V; Kovalev, G; Schibaev, N; Sengpiel, F; Vorobyov, V1
Kaneko, S; Yoshida, S1
Aiello, R; Camastra, C; Chimirri, S; Citraro, R; De Sarro, G; Donato, G; Mainardi, P; Perucca, E; Russo, E; Scicchitano, F1
Haugvicová, R; Kubová, H; Mares, P1
Armstrong, H; Cruz, LJ; Donevan, S; Jimenez, EC; Nielsen, J; Olivera, BM; Walker, C; White, HS; Zhou, LM1
Rubaj, A; Sieklucka-Dziuba, M; Zgodziński, W1
Maiorov, VI1
Aker, R; Gören, MZ; Onat, FY; Yananli, HR1
André, VM; Cepeda, C; Flores-Hernández, J; Levine, MS; Lobo, MK; Mathern, GW; Nguyen, S; Starling, AJ; Vinters, HV1
André, N; Gillardin, JM; Heulard, I; Verleye, M1
Rho, JM1
Akopian, G; Andersen, JK; Boonplueang, R; Kuhlenkamp, JF; Lu, SC; Stevenson, FF; Walsh, JP1
Isokawa, M1
Baraban, SC; Calcagnotto, ME1
Behr, J; Heinemann, U; Solger, J1
Breda, RV; Costa da Costa, J; de Abreu, DS; de Borba Cunha, F; de Oliveira, RM; Konno, K; Nihei, K; Palma, MS; Salamoni, SD; Tavares, AA; Venturin, GT1
Buño, W; Fernández de Sevilla, D; Galván, E; Garduño, J1
Azambuja, NA; Breda, RV; da Costa, JC; de Abreu, DS; Konno, K; Neto, EP; Nihei, K; Palma, MS; Salamoni, SD; Tavares, AA; Venturin, GT1
Sucher, NJ1
Sachdev, PS1
Choi, D; Harris, RH; Kohn, H; Kupferberg, HJ; Stables, JP; Stöhr, T; Walton, N; White, HS1
Kostopoulos, G; Moschovos, C; Papatheodoropoulos, C1
Iyengar, SS; Mott, DD1
Boxer, PA; Robichaud, LJ1
Bockaert, J; Fagni, L; Lafon-Cazal, M; Lerner-Natoli, M; Manzoni, O; Rondouin, G1
Apland, JP; Cann, FJ1
De Koninck, Y; Köhr, G; Mody, I1
Yoneda, Y1
Burke, JP; Hablitz, JJ1
Avoli, M; Köhling, R; Lücke, A; Nagao, T1
Hyvönen, M; Lahtinen, H; Miettinen, R; Riekkinen, PJ; Sirviö, J; Ylinen, A1
Heinemann, U; Igelmund, P; Leschinger, A; Stabel, J1
Luo, R; Schneiderman, JH; Sterling, CA1
Tamura, M; Yanagida, M1
Meldrum, BS1
Liang, WL; Shan, WS; Wu, XR1
Castrén, E; Lahtinen, H; Miettinen, R; Paljärvi, L; Riekkinen, PJ; Ylinen, A1
Bloms-Funke, P; Madeja, M; Musshoff, U; Speckmann, EJ1
Chapman, AG; Meldrum, BS1
Kubová, H; Mares, P1
Avoli, M; Barbarosie, M; Köhling, R; Lopantsev, V; Lücke, A; Nagao, T1
Davies, JA1
Alonso, A; Avoli, M; Nagao, T1
Debus, O; Kurlemann, G; Schuierer, G1
Bachelard, H; Morris, P; Taylor, A; Thatcher, N1
Bernard, C; Wheal, HV1
Jensen, FE; Wang, C1
Chakravarty, DN; Faingold, CL1
Avoli, M; Chodkiewicz, JP; Devaux, B; Kurcewicz, I; Louvel, J; Pumain, R1
Kobayashi, T; Suetsugi, M; Ushijima, I; Watanabe, K; Yamada, M; Yamaguchi, K1
DeFazio, T; Hablitz, JJ1
Haberly, LB; Kapur, A1
Behl, B; Hofmann, HP; Löscher, W; Potschka, H; Szabo, L; Treiber, HJ; Wlaź, P1
Godukhin, OV; Sem'ianov, AV1
Katsumori, H; Liu, H; Mazarati, AM; Penix, L; Shirasaka, Y; Thompson, KW; Wasterlain, CG1
Descombes, S; Psarropoulou, C1
Standley, CA1
Choi, I; Gwag, BJ; Huh, K; Jung, NP; Kim, EY; Ko, HW; Oh, YK; Park, EC; Shin, HC; Won, SJ1
Ludvig, N; Tang, HM1
Kapustecki, J; Pierzchała, K1
Mazarati, AM; Rogawski, MA; Wasterlain, CG1
Empson, RM; Gee, VJ; Newberry, NR; Sheardown, MJ1
Dannhardt, G; Kohl, BK1
Ho, IK; Jang, CG; Lee, SY; Loh, HH1
Brooks-Kayal, AR; Lynch, DR; Raol, YH1
Gustaw, K; Rubaj, A; Sieklucka-Dziuba, M; Zgodzinski, W1
Meador, KJ1
Ben-Ari, Y; Cherubini, E; Neuman, R1
Bowery, NG; Fletcher, AE; Price, GW; Ransom, R; Wilkin, GP; Wong, EH1
Louvel, J; Pumain, R1
Dudek, FE; Peacock, WJ; Wuarin, JP1
De Sarro, A; De Sarro, G; Meldrum, BS; Patel, S1
Rogawski, MA1
Lowe, DA; Roy, BL; Taschenberger, H1
Bingmann, D; Düsing, R; Grunze, H; Liu, Z; Walden, J1
Davies, JA; Lancaster, JM2
Pleuvry, BJ; Wildin, JD1
Brady, RJ; Smith, KL; Swann, JW1
Isokawa, M; Levesque, MF1
Hablitz, JJ; Lee, WL1
Avoli, M; Hwa, GG1
Ben-Ari, Y; Represa, A1
Mares, P; Velísek, L1
Frey, HH; Voits, M1
Buchwald, NA; Cepeda, C; Dudek, FE; Kim, YI; Peacock, WJ; Tasker, JG; Walsh, JP; Wuarin, JP1
Lehmenkühler, C; Speckmann, EJ; Walden, J1
Avoli, M; Drapeau, C; Louvel, J; Perreault, P; Pumain, R1
Ito, M; Mikawa, H; Mutoh, K; Oguro, K; Shiraishi, H; Shirasaka, Y; Tsuda, H1
Coenen, AM; Peeters, BW; van Rijn, CM; Vossen, JM1
Apland, JP; Braitman, DJ1
Aram, JA; Lodge, D; Martin, D; Millar, J; Pohler, G; Tomczyk, M; Zeman, S1
Haas, HL; Psarropoulou, C1
Anderson, WW; Clark, S; Stasheff, SF; Wilson, WA1
Anderson, AC; Gean, PW; Shinnick-Gallagher, P1
Anderson, WW; Swartzwelder, HS; Wilson, WA1
de Carolis, AS; Frank, C; Sagratella, S1
Aram, JA; Lodge, D1
Meldrum, B1
Hönack, D; Löscher, W; Nolting, B1
Bonhaus, DW; McNamara, JO; Shin, C1
Kurcewicz, I; Louvel, J; Pumain, R1
Hagberg, H; Hamberger, A; Jacobson, I; Lazarewicz, JW; Lehmann, A1
Heinemann, U1
Bortolotto, ZA; Calderazzo-Filho, LS; Cavalheiro, EA; Ikonomidou-Turski, C; Meldrum, BS; Turski, L; Turski, WA1

Reviews

16 review(s) available for n-methylaspartate and Aura

ArticleYear
A homozygous GRIN1 null variant causes a more severe phenotype of early infantile epileptic encephalopathy.
    American journal of medical genetics. Part A, 2022, Volume: 188, Issue:2

    Topics: Epilepsy; Humans; Infant; N-Methylaspartate; Nerve Tissue Proteins; Phenotype; Receptors, N-Methyl-D-Aspartate; Spasms, Infantile

2022
Gene mutations in paediatric epilepsies cause NMDA-pathy, and phasic and tonic GABA-pathy.
    Developmental medicine and child neurology, 2019, Volume: 61, Issue:8

    Topics: Brain; Child; Epilepsy; gamma-Aminobutyric Acid; Humans; Mutation; N-Methylaspartate

2019
[Autoimmune epilepsy].
    Revue medicale suisse, 2010, May-05, Volume: 6, Issue:247

    Topics: Autoantibodies; Biomarkers; Epilepsy; Glutamate Decarboxylase; Humans; Immunologic Factors; Limbic Encephalitis; N-Methylaspartate; Neuropsychological Tests; Paraneoplastic Syndromes; Potassium Channels, Voltage-Gated; Treatment Outcome

2010
Basic science behind the catastrophic epilepsies.
    Epilepsia, 2004, Volume: 45 Suppl 5

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Corticotropin-Releasing Hormone; Epilepsies, Myoclonic; Epilepsy; Humans; Infant; Infant, Newborn; Kynurenic Acid; Kynurenine; N-Methylaspartate; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Serotonin; Spasms, Infantile; Tryptophan

2004
Insights from molecular investigations of traditional Chinese herbal stroke medicines: implications for neuroprotective epilepsy therapy.
    Epilepsy & behavior : E&B, 2006, Volume: 8, Issue:2

    Topics: Apoptosis; Caspases; Drugs, Chinese Herbal; Epilepsy; Humans; N-Methylaspartate; Phytotherapy; Receptors, N-Methyl-D-Aspartate; Stroke

2006
Alternating and postictal psychoses: review and a unifying hypothesis.
    Schizophrenia bulletin, 2007, Volume: 33, Issue:4

    Topics: Brain; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Humans; N-Methylaspartate; Psychotic Disorders; Schizophrenia

2007
[Receptive mechanisms of excitatory amino acid signals].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1993, Volume: 113, Issue:7

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain Ischemia; Epilepsy; Ibotenic Acid; Kainic Acid; Ligands; N-Methylaspartate; Receptors, Amino Acid; Signal Transduction; Transcription Factors

1993
The role of glutamate in epilepsy and other CNS disorders.
    Neurology, 1994, Volume: 44, Issue:11 Suppl 8

    Topics: Animals; Central Nervous System Diseases; Epilepsy; Glutamic Acid; Humans; Lamotrigine; Mice; N-Methylaspartate; Parkinson Disease; Piperazines; Pyrimidines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Triazines

1994
Excitatory amino acid antagonists and epilepsy.
    Biochemical Society transactions, 1993, Volume: 21, Issue:1

    Topics: Amino Acids; Animals; Anticonvulsants; Binding, Competitive; Epilepsy; Humans; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate

1993
Mechanisms of action of antiepileptic drugs.
    Seizure, 1995, Volume: 4, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; N-Methylaspartate; Neural Pathways; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Valproic Acid

1995
[Stimulating amino acids in epilepsy: possibilities of treatment].
    Neurologia i neurochirurgia polska, 2000, Volume: 34 Suppl 1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anticonvulsants; Asparagine; Epilepsy; Female; Glutamine; Humans; Kainic Acid; Male; N-Methylaspartate; Synaptic Transmission

2000
The NMDA receptor complex: a promising target for novel antiepileptic strategies.
    Current medicinal chemistry, 2001, Volume: 8, Issue:11

    Topics: Animals; Anticonvulsants; Epilepsy; Humans; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate

2001
Role of excitatory amino acids in developmental epilepsies.
    Mental retardation and developmental disabilities research reviews, 2001, Volume: 7, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Epilepsy; Excitatory Amino Acids; Glutamic Acid; Humans; Kinetics; N-Methylaspartate; Synaptic Transmission

2001
Neurodevelopmental effects of antiepileptic drugs.
    Current neurology and neuroscience reports, 2002, Volume: 2, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Brain; Epilepsy; Epoxy Compounds; Female; Folic Acid; Free Radicals; Humans; Ischemia; Mental Disorders; N-Methylaspartate; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Risk Factors; Teratogens

2002
The NMDA receptor, NMDA antagonists and epilepsy therapy. A status report.
    Drugs, 1992, Volume: 44, Issue:3

    Topics: Binding Sites; Binding, Competitive; Epilepsy; Humans; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate

1992
Brief seizure episodes induce long-term potentiation and mossy fibre sprouting in the hippocampus.
    Trends in neurosciences, 1990, Volume: 13, Issue:8

    Topics: Animals; Epilepsy; Granulocytes; Hippocampus; Humans; N-Methylaspartate; Nerve Fibers; Nerve Regeneration; Neurons; Seizures; Time Factors

1990

Trials

1 trial(s) available for n-methylaspartate and Aura

ArticleYear
NMDA receptor alterations in neurons from pediatric cortical dysplasia tissue.
    Cerebral cortex (New York, N.Y. : 1991), 2004, Volume: 14, Issue:6

    Topics: Adolescent; Cells, Cultured; Cerebral Cortex; Child; Child, Preschool; Epilepsy; Humans; Infant; Magnesium; Membrane Potentials; N-Methylaspartate; Piperidines; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Reference Values

2004

Other Studies

112 other study(ies) available for n-methylaspartate and Aura

ArticleYear
N-methyl-d-aspartate (NMDA) receptor genetics: The power of paralog homology and protein dynamics in defining dominant genetic variants.
    American journal of medical genetics. Part A, 2022, Volume: 188, Issue:2

    Topics: Autism Spectrum Disorder; Epilepsy; Humans; N-Methylaspartate; Phenotype; Receptors, N-Methyl-D-Aspartate

2022
Anticonvulsive Effects and Pharmacokinetic Profile of Cannabidiol (CBD) in the Pentylenetetrazol (PTZ) or N-Methyl-D-Aspartate (NMDA) Models of Seizures in Infantile Rats.
    International journal of molecular sciences, 2021, Dec-22, Volume: 23, Issue:1

    Topics: Animals; Anticonvulsants; Brain; Cannabidiol; Disease Models, Animal; Epilepsy; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Wistar; Seizures

2021
An Epilepsy-Associated Mutation of Salt-Inducible Kinase 1 Increases the Susceptibility to Epileptic Seizures and Interferes with Adrenocorticotropic Hormone Therapy for Infantile Spasms in Mice.
    International journal of molecular sciences, 2022, Jul-18, Volume: 23, Issue:14

    Topics: Adrenocorticotropic Hormone; Animals; Electroencephalography; Epilepsy; Male; Mice; Mutation; N-Methylaspartate; Protein Serine-Threonine Kinases; Seizures; Spasm

2022
GluN2C selective inhibition is a target to develop new antiepileptic compounds.
    Epilepsia, 2022, Volume: 63, Issue:11

    Topics: Animals; Anticonvulsants; Epilepsy; Humans; Infant; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures; Tuberous Sclerosis

2022
Insulin-Like Growth Factor-1 Promotes Synaptogenesis Signaling, a Major Dysregulated Pathway in Malformation of Cortical Development, in a Rat Model.
    Molecular neurobiology, 2023, Volume: 60, Issue:6

    Topics: Animals; Disease Models, Animal; Epilepsy; Female; Humans; Infant; Insulin-Like Growth Factor I; N-Methylaspartate; Pregnancy; Proteomics; Rats; Spasm

2023
Missense variants in RPH3A cause defects in excitatory synaptic function and are associated with a clinically variable neurodevelopmental disorder.
    Genetics in medicine : official journal of the American College of Medical Genetics, 2023, Volume: 25, Issue:11

    Topics: Animals; Autism Spectrum Disorder; Epilepsy; Humans; Mutation, Missense; N-Methylaspartate; Neurons; Rabphilin-3A; Rats

2023
How can methylprednisolone work on epileptic spasms with malformation of cortical development?
    The European journal of neuroscience, 2019, Volume: 50, Issue:12

    Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Brain; Disease Models, Animal; Epilepsy; Female; Methylprednisolone; N-Methylaspartate; Neurogenesis; Pregnancy; Prenatal Exposure Delayed Effects; Rats

2019
Acteoside Isolated from Colebrookea oppositifolia Smith Attenuates Epilepsy in Mice Via Modulation of Gamma-Aminobutyric Acid Pathways.
    Neurotoxicity research, 2020, Volume: 38, Issue:4

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Glucosides; Lamiaceae; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Phenols; Plant Extracts; Plant Roots; Signal Transduction

2020
Personalized therapy in a GRIN1 mutated girl with intellectual disability and epilepsy.
    Clinical dysmorphology, 2018, Volume: 27, Issue:1

    Topics: Child; Epilepsy; Exome Sequencing; Female; Humans; Intellectual Disability; N-Methylaspartate; Nerve Tissue Proteins; Precision Medicine; Receptors, N-Methyl-D-Aspartate

2018
Navigating the genetic landscape of childhood epilepsy: a new perspective?
    Developmental medicine and child neurology, 2019, Volume: 61, Issue:8

    Topics: Child; Epilepsy; gamma-Aminobutyric Acid; Humans; Mutation; N-Methylaspartate

2019
Changes in brain cortex sensitivity to epileptogens under conditions of ketogenic diet.
    Bulletin of experimental biology and medicine, 2013, Volume: 154, Issue:4

    Topics: Animals; Cerebral Cortex; Diet, Ketogenic; Epilepsy; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Penicillin G; Rats; Rats, Wistar; Strychnine

2013
Ranolazine reduces neuronal excitability by interacting with inactivated states of brain sodium channels.
    Molecular pharmacology, 2014, Volume: 85, Issue:1

    Topics: Acetanilides; Action Potentials; Animals; Anticonvulsants; Cells, Cultured; Computer Simulation; Epilepsy; Hippocampus; Humans; Markov Chains; N-Methylaspartate; NAV1.1 Voltage-Gated Sodium Channel; NAV1.2 Voltage-Gated Sodium Channel; Neurons; Patch-Clamp Techniques; Piperazines; Protein Binding; Protein Conformation; Ranolazine; Rats; Voltage-Gated Sodium Channels

2014
Environmental enrichment restores CA1 hippocampal LTP and reduces severity of seizures in epileptic mice.
    Experimental neurology, 2014, Volume: 261

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Biophysics; CA1 Region, Hippocampal; Disease Models, Animal; Electric Stimulation; Environment; Epilepsy; Excitatory Amino Acid Agonists; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Transgenic; Mutation; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques

2014
Nodding syndrome in Tanzania may not be associated with circulating anti-NMDA-and anti-VGKC receptor antibodies or decreased pyridoxal phosphate serum levels-a pilot study.
    African health sciences, 2014, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Aged; Autoantibodies; Case-Control Studies; Epilepsy; Female; Humans; Male; Middle Aged; N-Methylaspartate; Neurons; Nodding Syndrome; Pilot Projects; Potassium Channels, Voltage-Gated; Pyridoxal Phosphate; Seizures; Tanzania

2014
Enhanced long-term potentiation in mature rats in a model of epileptic spasms with betamethasone-priming and postnatal N-methyl-D-aspartate administration.
    Epilepsia, 2016, Volume: 57, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Betamethasone; Disease Models, Animal; Epilepsy; Female; Long-Term Potentiation; Male; N-Methylaspartate; Organ Culture Techniques; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley

2016
Abnormal Ca2+ mobilization in hippocampal slices of epileptic animals fed a zinc-deficient diet.
    Epilepsy research, 2009, Volume: 83, Issue:1

    Topics: Animals; Calcium; Calcium Signaling; Diet; Electric Stimulation; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Exocytosis; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mossy Fibers, Hippocampal; N-Methylaspartate; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Presynaptic; Seizures; Zinc

2009
Validation of anticonvulsant and sedative activity of six medicinal plants.
    Epilepsy & behavior : E&B, 2009, Volume: 14, Issue:3

    Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Excitatory Amino Acid Agonists; Hypnotics and Sedatives; Isoniazid; Male; Medicine, African Traditional; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Plants, Medicinal; Sleep Initiation and Maintenance Disorders; Stereotyped Behavior; Strychnine

2009
Eukaryotic expression and purification of anti-epilepsy peptide of Buthus martensii Karsch and its protein interactions.
    Molecular and cellular biochemistry, 2009, Volume: 330, Issue:1-2

    Topics: Animals; Cloning, Molecular; Epilepsy; Genetic Vectors; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Hippocampus; N-Methylaspartate; Pichia; Protein Binding; Protein Interaction Mapping; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Synaptosomal-Associated Protein 25

2009
Anticonvulsant effects of Searsia dentata (Anacardiaceae) leaf extract in rats.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:6

    Topics: Anacardiaceae; Animals; Anticonvulsants; Bicuculline; Disease Models, Animal; Epilepsy; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures

2010
N-methyl-D-aspartate-induced oscillatory properties in neocortical pyramidal neurons from patients with epilepsy.
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2010, Volume: 27, Issue:6

    Topics: Action Potentials; Adolescent; Anesthetics, Local; Biological Clocks; Biophysics; Child; Child, Preschool; Drug Interactions; Epilepsy; Excitatory Amino Acid Agonists; Female; Humans; In Vitro Techniques; Male; N-Methylaspartate; Neocortex; Patch-Clamp Techniques; Pyramidal Cells; Tetrodotoxin

2010
Neuronal bursting properties in focal and parafocal regions in pediatric neocortical epilepsy stratified by histology.
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2010, Volume: 27, Issue:6

    Topics: Action Potentials; Adolescent; Bicuculline; Child; Child, Preschool; Electric Stimulation; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA-A Receptor Antagonists; Humans; In Vitro Techniques; Male; N-Methylaspartate; Neocortex; Neurons; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Piperazines

2010
Cortical and hippocampal EEG effects of neurotransmitter agonists in spontaneously hypertensive vs. kainate-treated rats.
    Brain research, 2011, Apr-06, Volume: 1383

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Baclofen; Clonidine; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Epilepsy; Excitatory Amino Acid Agonists; Frontal Lobe; Hippocampus; Hypertension; Kainic Acid; Muscimol; N-Methylaspartate; Neurotransmitter Agents; Rats; Rats, Inbred SHR; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate

2011
[Selection of proper antiepileptic drugs].
    Rinsho shinkeigaku = Clinical neurology, 2010, Volume: 50, Issue:11

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anticonvulsants; Drug Therapy, Combination; Epilepsy; GABA Antagonists; Humans; N-Methylaspartate; Precision Medicine; Sodium Channel Blockers

2010
Protective activity of α-lactoalbumin (ALAC), a whey protein rich in tryptophan, in rodent models of epileptogenesis.
    Neuroscience, 2012, Dec-13, Volume: 226

    Topics: Animals; Convulsants; Epilepsy; Epilepsy, Absence; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kynurenic Acid; Lactalbumin; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Milk Proteins; N-Methylaspartate; Pentylenetetrazole; Pilocarpine; Rats; Tryptophan; Whey Proteins

2012
Interaction of excitatory amino acid agonists with cortical afterdischarges in developing rats.
    Epilepsia, 2002, Volume: 43 Suppl 5

    Topics: Aging; Animals; Cerebral Cortex; Electric Stimulation; Electrophysiology; Epilepsy; Excitatory Amino Acid Agonists; Homocysteine; Kainic Acid; N-Methylaspartate; Rats; Rats, Wistar

2002
Conantokin-L, a new NMDA receptor antagonist: determinants for anticonvulsant potency.
    Epilepsy research, 2002, Volume: 51, Issue:1-2

    Topics: Amino Acid Sequence; Animals; Anticonvulsants; Cerebellar Cortex; Cloning, Molecular; Conotoxins; Disease Models, Animal; DNA, Complementary; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Antagonists; Female; Intercellular Signaling Peptides and Proteins; Male; Mice; Molecular Sequence Data; Mollusk Venoms; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Peptide Biosynthesis; Peptides; Receptors, N-Methyl-D-Aspartate; Sleep; Snails; Time Factors

2002
The epileptogenic effect of seizures induced by hypoxia: the role of NMDA and AMPA/KA antagonists.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 74, Issue:2

    Topics: Animals; Avoidance Learning; Bicuculline; Brain Chemistry; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hypoxia; Mice; N-Methylaspartate; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures

2003
NMDA-dependent and NMDA-independent neural processes in the bicucculline-disinhibited motor cortex of the cat during the acquisition and reproduction of a conditioned paw-on-support placing reflex.
    Neuroscience and behavioral physiology, 2003, Volume: 33, Issue:4

    Topics: Animals; Bicuculline; Cats; Conditioning, Operant; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy; GABA Antagonists; GABA-A Receptor Antagonists; Motor Cortex; N-Methylaspartate; Neurons

2003
Extracellular concentrations of catecholamines and amino acids in the dorsomedial hypothalamus of kindled rats. A microdialysis study.
    Pharmacology, 2003, Volume: 68, Issue:4

    Topics: Animals; Bicuculline; Blood Pressure; Chromatography, High Pressure Liquid; Dopamine; Dorsomedial Hypothalamic Nucleus; Epilepsy; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Kindling, Neurologic; Male; Microdialysis; N-Methylaspartate; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2003
Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents.
    Brain research, 2004, Jul-09, Volume: 1013, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Non-Narcotic; Animals; Binding, Competitive; Electroshock; Epilepsy; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nefopam; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Sodium Channels; Synaptic Transmission; Tritium

2004
Increased susceptibility of glutathione peroxidase-1 transgenic mice to kainic acid-related seizure activity and hippocampal neuronal cell death.
    Experimental neurology, 2005, Volume: 192, Issue:1

    Topics: Animals; Cell Death; Cells, Cultured; Disease Models, Animal; Epilepsy; Genetic Predisposition to Disease; Glutathione Disulfide; Glutathione Peroxidase; Hippocampus; Kainic Acid; Mice; Mice, Transgenic; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Organ Culture Techniques; Oxidative Stress; Receptors, N-Methyl-D-Aspartate; Up-Regulation

2005
N-methyl-D-aspartic acid-induced and Ca-dependent neuronal swelling and its retardation by brain-derived neurotrophic factor in the epileptic hippocampus.
    Neuroscience, 2005, Volume: 131, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Brain-Derived Neurotrophic Factor; Calcium; Cell Size; Chelating Agents; Cytosol; Dentate Gyrus; Egtazic Acid; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Light; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Thapsigargin

2005
Prolonged NMDA-mediated responses, altered ifenprodil sensitivity, and epileptiform-like events in the malformed hippocampus of methylazoxymethanol exposed rats.
    Journal of neurophysiology, 2005, Volume: 94, Issue:1

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Methylazoxymethanol Acetate; N-Methylaspartate; Patch-Clamp Techniques; Piperidines; Rats

2005
Electrical and chemical long-term depression do not attenuate low-Mg2+-induced epileptiform activity in the entorhinal cortex.
    Epilepsia, 2005, Volume: 46, Issue:4

    Topics: Animals; Disease Models, Animal; Electric Stimulation; Electric Stimulation Therapy; Entorhinal Cortex; Epilepsy; Humans; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Magnesium Deficiency; Mice; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures

2005
Antiepileptic effect of acylpolyaminetoxin JSTX-3 on rat hippocampal CA1 neurons in vitro.
    Brain research, 2005, Jun-28, Volume: 1048, Issue:1-2

    Topics: Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Electric Stimulation; Epilepsy; Excitatory Amino Acid Agonists; Heterocyclic Compounds; Hippocampus; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; N-Methylscopolamine; Neurons; Patch-Clamp Techniques; Polyamines; Rats; Rats, Wistar

2005
1-Ethyl-2-benzimidazolinone (EBIO) suppresses epileptiform activity in in vitro hippocampus.
    Neuropharmacology, 2005, Volume: 49, Issue:3

    Topics: Action Potentials; Algorithms; Animals; Anticonvulsants; Apamin; Benzimidazoles; Calcium Channel Agonists; Electric Stimulation; Electrophysiology; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Pyramidal Cells; Rats; Small-Conductance Calcium-Activated Potassium Channels; Synaptic Transmission

2005
The antiepileptic activity of JSTX-3 is mediated by N-methyl-D-aspartate receptors in human hippocampal neurons.
    Neuroreport, 2005, Nov-07, Volume: 16, Issue:16

    Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adolescent; Adult; Anticonvulsants; Child; Electrophysiology; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Heterocyclic Compounds; Hippocampus; Humans; In Vitro Techniques; Magnesium; Male; Middle Aged; N-Methylaspartate; Neurons; Polyamines; Receptors, N-Methyl-D-Aspartate

2005
Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy.
    Epilepsy research, 2007, Volume: 74, Issue:2-3

    Topics: Acetamides; Animals; Anticonvulsants; Bicuculline; Cobalt; Convulsants; Electroshock; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epilepsy, Reflex; Excitatory Amino Acid Agonists; GABA Antagonists; Homocysteine; Kindling, Neurologic; Lacosamide; Male; Mice; N-Methylaspartate; Neurotoxicity Syndromes; Pentylenetetrazole; Picrotoxin; Rats; Rats, Sprague-Dawley; Status Epilepticus

2007
Long-term potentiation of high-frequency oscillation and synaptic transmission characterize in vitro NMDA receptor-dependent epileptogenesis in the hippocampus.
    Neurobiology of disease, 2008, Volume: 29, Issue:2

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Epilepsy; Excitatory Amino Acid Agents; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Magnesium; Male; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission

2008
Neuregulin blocks synaptic strengthening after epileptiform activity in the rat hippocampus.
    Brain research, 2008, May-07, Volume: 1208

    Topics: Animals; Animals, Newborn; Bicuculline; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Neuregulins; Neurons; Potassium; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission

2008
Polyamine modulation of excitatory amino acid responses in the rat cortical wedge.
    Neuropharmacology, 1993, Volume: 32, Issue:10

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Biogenic Polyamines; Cerebral Cortex; Epilepsy; In Vitro Techniques; Male; Membrane Potentials; Models, Biological; N-Methylaspartate; Rats; Rats, Wistar; Spermine

1993
The role of free radicals in NMDA-dependent neurotoxicity.
    Progress in brain research, 1994, Volume: 103

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebellar Cortex; Cyclic GMP; Electron Spin Resonance Spectroscopy; Enzyme Activation; Epilepsy; Feedback; Free Radicals; Glutamic Acid; Guanylate Cyclase; Kindling, Neurologic; Mice; Molsidomine; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Receptors, N-Methyl-D-Aspartate

1994
Anticonvulsant effects of memantine and MK-801 in guinea pig hippocampal slices.
    Brain research bulletin, 1995, Volume: 37, Issue:3

    Topics: Animals; Anticonvulsants; Dizocilpine Maleate; Electric Stimulation; Epilepsy; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Memantine; Membrane Potentials; N-Methylaspartate; Pyramidal Cells; Synapses; Synaptic Transmission

1995
Properties of NMDA receptor channels in neurons acutely isolated from epileptic (kindled) rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:8

    Topics: Adenosine Triphosphate; Animals; Calcium; Electric Conductivity; Electrophysiology; Epilepsy; Ion Channels; Kindling, Neurologic; Magnesium; Male; N-Methylaspartate; Neurons; Phosphates; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1993
Modulation of epileptiform activity by metabotropic glutamate receptors in immature rat neocortex.
    Journal of neurophysiology, 1995, Volume: 73, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebral Cortex; Epilepsy; Evoked Potentials; Humans; Infant, Newborn; N-Methylaspartate; Neurons; Rats; Receptors, Metabotropic Glutamate

1995
Synchronous potentials and elevations in [K+]o in the adult rat entorhinal cortex maintained in vitro.
    Neuroscience letters, 1995, Feb-13, Volume: 185, Issue:3

    Topics: 4-Aminopyridine; Animals; Entorhinal Cortex; Epilepsy; Membrane Potentials; N-Methylaspartate; Potassium; Rats; Rats, Sprague-Dawley

1995
Preservation of hippocampal NMDA receptors may be crucial for spatial learning after epileptic seizures in rats.
    Brain research, 1993, Oct-15, Volume: 625, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Electric Stimulation; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Learning; Male; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Somatostatin; Space Perception

1993
Pharmacological and electrographic properties of epileptiform activity induced by elevated K+ and lowered Ca2+ and Mg2+ concentration in rat hippocampal slices.
    Experimental brain research, 1993, Volume: 96, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Carbachol; Electrophysiology; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; Magnesium; Membrane Potentials; Microelectrodes; N-Methylaspartate; Neurons; Potassium; Pyramidal Tracts; Quaternary Ammonium Compounds; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Temperature

1993
Hippocampal plasticity following epileptiform bursting produced by GABAA antagonists.
    Neuroscience, 1994, Volume: 59, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Epilepsy; Evoked Potentials; GABA Antagonists; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neuronal Plasticity; Penicillins; Pyramidal Cells; Seizures; Time Factors

1994
Changes in oxygenation states of rat brain tissues during glutamate-related epileptic seizures--near-infrared study.
    Advances in experimental medicine and biology, 1994, Volume: 345

    Topics: Animals; Brain; Dizocilpine Maleate; Electroencephalography; Electron Transport Complex IV; Epilepsy; Glutamates; Glutamic Acid; Hemoglobins; Kainic Acid; Male; N-Methylaspartate; Oxidation-Reduction; Oxygen; Rats; Rats, Wistar; Spectrophotometry, Infrared

1994
[Roles of glutamate receptor in c-fos gene expression and epilepsy susceptibility in rats].
    Zhonghua yi xue za zhi, 1994, Volume: 74, Issue:8

    Topics: Animals; Disease Susceptibility; Epilepsy; Female; Gene Expression; Genes, fos; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger

1994
NMDA-sensitive [3H]glutamate binding in the epileptic rat hippocampus: an autoradiographic study.
    Neuroreport, 1993, Volume: 4, Issue:1

    Topics: Animals; Autoradiography; Cell Death; Electroencephalography; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Histocytochemistry; Kinetics; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1993
Effects of the epileptogenic agent bicuculline methiodide on membrane currents induced by N-methyl-D-aspartate and kainate (oocyte; Xenopus laevis).
    Brain research, 1994, Mar-07, Volume: 639, Issue:1

    Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Electric Conductivity; Epilepsy; Kainic Acid; N-Methylaspartate; Oocytes; Xenopus laevis

1994
Suppression of cortical epileptic afterdischarges by ketamine is not stable during ontogenesis in rats.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:3

    Topics: Animals; Anticonvulsants; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Female; Ketamine; Movement; N-Methylaspartate; Rats; Rats, Wistar

1995
Synchronous GABA-mediated potentials and epileptiform discharges in the rat limbic system in vitro.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Jun-15, Volume: 16, Issue:12

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Animals; Disease Models, Animal; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Limbic System; Male; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin Receptor Agonists

1996
Epileptiform activity induced by pilocarpine in the rat hippocampal-entorhinal slice preparation.
    Neuroscience, 1996, Volume: 72, Issue:2

    Topics: Animals; Electrophysiology; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Microelectrodes; Muscarinic Agonists; N-Methylaspartate; Pilocarpine; Piperazines; Rats; Rats, Sprague-Dawley

1996
Dextromethorphan in molybdenum cofactor deficiency.
    European journal of pediatrics, 1996, Volume: 155, Issue:5

    Topics: Anticonvulsants; Child, Preschool; Coenzymes; Dextromethorphan; Epilepsy; Humans; Male; Metabolism, Inborn Errors; Metalloproteins; Molybdenum Cofactors; N-Methylaspartate; Pteridines

1996
High-field MRS studies in brain slices.
    Magnetic resonance imaging, 1995, Volume: 13, Issue:8

    Topics: Animals; Cerebral Cortex; Culture Techniques; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Ion Channels; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Synaptic Transmission

1995
A role for synaptic and network plasticity in controlling epileptiform activity in CA1 in the kainic acid-lesioned rat hippocampus in vitro.
    The Journal of physiology, 1996, Aug-15, Volume: 495 ( Pt 1)

    Topics: Animals; Disease Models, Animal; Epilepsy; Hippocampus; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neuronal Plasticity; Rats; Rats, Wistar; Synaptic Transmission

1996
Age dependence of NMDA receptor involvement in epileptiform activity in rat hippocampal slices.
    Epilepsy research, 1996, Volume: 23, Issue:2

    Topics: Age Factors; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Hippocampus; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate

1996
Aberrant neuronal responsiveness in the genetically epilepsy-prone rat: acoustic responses and influences of the central nucleus upon the external nucleus of inferior colliculus.
    Brain research, 1997, Jul-04, Volume: 761, Issue:2

    Topics: Acoustic Stimulation; Animals; Electric Stimulation; Electrophysiology; Epilepsy; Excitatory Amino Acid Agonists; Inferior Colliculi; Microinjections; N-Methylaspartate; Neurons; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Stimulation, Chemical

1997
GABAA inhibition controls the calcium flows during NMDA-dependent epileptiform activity in human epileptogenic neocortex.
    Epilepsy research. Supplement, 1996, Volume: 12

    Topics: Brain Mapping; Calcium Channels; Cerebral Cortex; Culture Techniques; Electroencephalography; Epilepsy; Evoked Potentials; gamma-Aminobutyric Acid; Humans; N-Methylaspartate; Neural Inhibition; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate

1996
Cocaine: evidence for NMDA-, beta-carboline- and dopaminergic-mediated seizures in mice.
    Brain research, 1998, Jun-29, Volume: 797, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzodiazepines; Brain Chemistry; Calcium; Carbolines; Cocaine; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Epilepsy; Excitatory Amino Acid Agonists; GABA Agonists; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate

1998
Excitability changes in freeze-induced neocortical microgyria.
    Epilepsy research, 1998, Volume: 32, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Brain; Cerebral Cortex; Electric Stimulation; Epilepsy; Freezing; Functional Laterality; Humans; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neocortex; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley

1998
Duration of NMDA-dependent synaptic potentiation in piriform cortex in vivo is increased after epileptiform bursting.
    Journal of neurophysiology, 1998, Volume: 80, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Electric Stimulation; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Long-Term Potentiation; Male; N-Methylaspartate; Neural Inhibition; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Reaction Time; Synapses; Theta Rhythm

1998
LU 73068, a new non-NMDA and glycine/NMDA receptor antagonist: pharmacological characterization and comparison with NBQX and L-701,324 in the kindling model of epilepsy.
    British journal of pharmacology, 1998, Volume: 125, Issue:6

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinolones; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Tritium

1998
[Long-lasting reduction of the threshold of epileptiform discharges induced by periodic removal of extracellular Mg2+ in slices of CA1 field of the rat hippocampus].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 1998, Volume: 84, Issue:12

    Topics: Action Potentials; Animals; Calcium Channels; Calcium Channels, L-Type; Electrophysiology; Epilepsy; Extracellular Space; Hippocampus; In Vitro Techniques; Magnesium Deficiency; N-Methylaspartate; Rats

1998
Seizure-induced hippocampal damage and chronic epilepsy: a hebbian theory of epileptogenesis.
    Advances in neurology, 1999, Volume: 79

    Topics: Animals; Chronic Disease; Dentate Gyrus; Epilepsy; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Kindling, Neurologic; Long-Term Potentiation; Models, Neurological; Mossy Fibers, Hippocampal; N-Methylaspartate; Neural Inhibition; Neural Pathways; Rats; Rats, Wistar; Status Epilepticus; Synapses

1999
Differential bicuculline-induced epileptogenesis in rat neonatal, juvenile and adult CA3 pyramidal neurons in vitro.
    Brain research. Developmental brain research, 1999, Oct-20, Volume: 117, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aging; Animals; Animals, Newborn; Bicuculline; Epilepsy; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; N-Methylaspartate; Piperazines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate

1999
N-methyl-D-aspartate receptor binding is altered and seizure potential reduced in pregnant rats.
    Brain research, 1999, Oct-09, Volume: 844, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Convulsants; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; N-Methylaspartate; Pregnancy; Pregnancy, Animal; Radioligand Assay; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tritium

1999
Nuclear factor kappa B-mediated kainate neurotoxicity in the rat and hamster hippocampus.
    Neuroscience, 1999, Volume: 94, Issue:1

    Topics: Animals; Cell Death; Cell Nucleus; Cricetinae; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Kainic Acid; Mesocricetus; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; NF-kappa B; Rats; Rats, Sprague-Dawley

1999
Cellular electrophysiological changes in the hippocampus of freely behaving rats during local microdialysis with epileptogenic concentration of N-methyl-D-aspartate.
    Brain research bulletin, 2000, Volume: 51, Issue:3

    Topics: Action Potentials; Animals; Electroencephalography; Electrophysiology; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Male; Microdialysis; N-Methylaspartate; Neurons; Osmolar Concentration; Rats; Rats, Long-Evans

2000
Re: Mazarati et al. "...clinically available [antiepileptic drug] with a moderate affinity for the glycine site of the N-methyl-D-aspartate (NMDA) receptor".
    Epilepsia, 2000, Volume: 41, Issue:7

    Topics: Anticonvulsants; Epilepsy; Felbamate; Glycine; Humans; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate

2000
Chlormethiazole inhibits epileptiform activity by potentiating GABA(A) receptor function.
    Brain research, 2000, Nov-24, Volume: 884, Issue:1--2

    Topics: Action Potentials; Animals; Bicuculline; Cerebral Cortex; Chlormethiazole; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Valine

2000
Lack of mu-opioid receptor leads to an increase in the NMDA receptor subunit mRNA expression and NMDA-induced convulsion.
    Brain research. Molecular brain research, 2001, Oct-19, Volume: 94, Issue:1-2

    Topics: Animals; Epilepsy; Excitatory Amino Acid Agonists; Gene Expression; In Situ Hybridization; Injections, Intraventricular; Mice; Mice, Knockout; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; RNA, Messenger

2001
Nociceptin, OP4 receptor ligand in different models of experimental epilepsy.
    Peptides, 2002, Volume: 23, Issue:3

    Topics: Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Epilepsy; Female; Mice; N-Methylaspartate; Nociceptin; Nociceptin Receptor; Opioid Peptides; Pentylenetetrazole; Receptors, Opioid

2002
Do NMDA antagonists suppress interictal discharges?
    Epilepsy research. Supplement, 1992, Volume: 8

    Topics: Animals; Anticonvulsants; Convulsants; Culture Techniques; Dose-Response Relationship, Drug; Epilepsy; Hippocampus; Magnesium; Membrane Potentials; N-Methylaspartate; Nerve Net; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

1992
Autoradiography and interaction of modulators of NMDA receptor activation.
    Epilepsy research. Supplement, 1992, Volume: 8

    Topics: Amino Acids; Animals; Anticonvulsants; Autoradiography; Binding, Competitive; Brain; Brain Mapping; Convulsants; Culture Techniques; Dizocilpine Maleate; Epilepsy; Glycine; N-Methylaspartate; Neurons; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Membranes; Synaptic Transmission

1992
N-methyl-D-aspartate-mediated responses in epileptic cortex in humans: an in-vitro study.
    Epilepsy research. Supplement, 1992, Volume: 8

    Topics: Calcium; Calcium Channels; Cerebral Cortex; Culture Techniques; Electroencephalography; Epilepsy; Frontal Lobe; Humans; N-Methylaspartate; Psychosurgery; Receptors, N-Methyl-D-Aspartate; Temporal Lobe

1992
Single-electrode voltage-clamp analysis of the N-methyl-D-aspartate component of synaptic responses in neocortical slices from children with intractable epilepsy.
    Journal of neurophysiology, 1992, Volume: 67, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Aging; Bicuculline; Cerebral Cortex; Child; Child, Preschool; Electric Stimulation; Electrophysiology; Epilepsy; Evoked Potentials; Female; Humans; Infant; Male; Membrane Potentials; Microelectrodes; N-Methylaspartate; Neurons; Quinoxalines; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission

1992
Excitatory neurotransmitters in the lateral habenula and pedunculopontine nucleus of rat modulate limbic seizures induced by pilocarpine.
    Brain research, 1992, Sep-25, Volume: 591, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Electroencephalography; Epilepsy; Glutamine; Kainic Acid; Limbic System; Male; N-Methylaspartate; Neurotransmitter Agents; Pilocarpine; Pons; Rats; Rats, Wistar; Thalamus

1992
Effects of a metabotropic glutamate agonist, trans-ACPD, on cortical epileptiform activity.
    Neuroreport, 1992, Volume: 3, Issue:7

    Topics: Animals; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Drug; Epilepsy; Glutamates; In Vitro Techniques; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Neurotoxins; Rats; Rats, Wistar; Receptors, Glutamate; Stereoisomerism

1992
Calcium antagonistic effects of carbamazepine as a mechanism of action in neuropsychiatric disorders: studies in calcium dependent model epilepsies.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1992, Volume: 2, Issue:4

    Topics: Animals; Calcium Channel Blockers; Carbamazepine; Epilepsy; Extracellular Space; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium; Microelectrodes; N-Methylaspartate; Psychotic Disorders; Verapamil

1992
Carbamazepine inhibits NMDA-induced depolarizations in cortical wedges prepared from DBA/2 mice.
    Experientia, 1992, Aug-15, Volume: 48, Issue:8

    Topics: Animals; Carbamazepine; Cerebral Cortex; Dose-Response Relationship, Drug; Epilepsy; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred DBA; N-Methylaspartate

1992
Tolerance to the anticonvulsant effects of clobazam in mice.
    Neuropharmacology, 1992, Volume: 31, Issue:2

    Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Dose-Response Relationship, Drug; Drug Tolerance; Epilepsy; Mice; Mice, Inbred Strains; N-Methylaspartate; Pentylenetetrazole; Seizures

1992
Calcium modulation of the N-methyl-D-aspartate (NMDA) response and electrographic seizures in immature hippocampus.
    Neuroscience letters, 1991, Mar-11, Volume: 124, Issue:1

    Topics: Age Factors; Animals; Calcium; Calcium Channels; Drug Interactions; Epilepsy; GABA Antagonists; Hippocampus; Ion Channel Gating; N-Methylaspartate; Penicillins; Picrotoxin; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin

1991
Increased NMDA responses and dendritic degeneration in human epileptic hippocampal neurons in slices.
    Neuroscience letters, 1991, Nov-11, Volume: 132, Issue:2

    Topics: Adolescent; Adult; Dendrites; Electric Stimulation; Epilepsy; Hippocampus; Humans; N-Methylaspartate; Nerve Degeneration; Neurons; Synapses; Synaptic Transmission

1991
Initiation of epileptiform activity by excitatory amino acid receptors in the disinhibited rat neocortex.
    Journal of neurophysiology, 1991, Volume: 65, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cerebral Cortex; Electricity; Epilepsy; Female; Male; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate

1991
The involvement of excitatory amino acids in neocortical epileptogenesis: NMDA and non-NMDA receptors.
    Experimental brain research, 1991, Volume: 86, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Dizocilpine Maleate; Electric Stimulation; Epilepsy; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate

1991
Desmethylimipramine potentiates NMDA responses in a mouse cortical slice preparation.
    Neuroreport, 1991, Volume: 2, Issue:11

    Topics: Action Potentials; Animals; Anticonvulsants; Cerebral Cortex; Convulsants; Corpus Callosum; Desipramine; Epilepsy; Female; Ion Channels; Ketamine; Magnesium; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Stimulation, Chemical

1991
The action of clonazepam against seizures induced by N-methyl-D-aspartate in rats during ontogenesis.
    Homeostasis in health and disease : international journal devoted to integrative brain functions and homeostatic systems, 1991, Volume: 33, Issue:4

    Topics: Aging; Animals; Clonazepam; Epilepsy; Male; N-Methylaspartate; Rats; Rats, Inbred Strains

1991
Effect of psychotropic agents on a model of absence epilepsy in rats.
    Neuropharmacology, 1991, Volume: 30, Issue:6

    Topics: Animals; Antidepressive Agents; Dextroamphetamine; Electroencephalography; Epilepsy; Female; Levodopa; Male; Memantine; Morphine; N-Methylaspartate; Parasympatholytics; Psychotropic Drugs; Rats; Rats, Inbred Strains

1991
Synaptic transmission in human neocortex removed for treatment of intractable epilepsy in children.
    Annals of neurology, 1990, Volume: 28, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Adolescent; Bicuculline; Child; Child, Preschool; Epilepsy; Female; GABA Antagonists; Humans; Infant; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Psychosurgery; Pyramidal Tracts; Spasms, Infantile; Synapses; Synaptic Transmission

1990
Decrease of N-methyl-D-aspartate responses by noradrenaline in the rat motorcortex in vivo.
    Neuroscience letters, 1991, Jan-02, Volume: 121, Issue:1-2

    Topics: Animals; Clonidine; Electroencephalography; Epilepsy; Evoked Potentials; Isoproterenol; Motor Cortex; N-Methylaspartate; Neural Pathways; Norepinephrine; Phenylephrine; Rats

1991
Epileptiform activity induced by low chloride medium in the CA1 subfield of the hippocampal slice.
    Journal of neurophysiology, 1990, Volume: 64, Issue:6

    Topics: Animals; Anticonvulsants; Chlorides; Electric Stimulation; Electrodes; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Piperazines; Pyramidal Tracts; Rats; Rats, Inbred Strains

1990
NMDA-sensitive L-[3H]glutamate binding in cerebral cortex of El mice.
    Epilepsy research, 1990, Volume: 6, Issue:3

    Topics: Animals; Cerebral Cortex; Disease Models, Animal; Disease Susceptibility; Epilepsy; Genetic Predisposition to Disease; Glutamates; Membranes; Mice; Mice, Inbred Strains; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Tritium

1990
Involvement of NMDA receptors in non-convulsive epilepsy in WAG/Rij rats.
    Life sciences, 1990, Volume: 47, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Electroencephalography; Epilepsy; Female; Injections, Intraventricular; Male; N-Methylaspartate; Rats; Rats, Mutant Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter

1990
Effects of non-opioid antitussives on epileptiform activity and NMDA responses in hippocampal and olfactory cortex slices.
    Brain research, 1990, Oct-08, Volume: 529, Issue:1-2

    Topics: Animals; Antitussive Agents; Cyclopentanes; Dextromethorphan; Electric Stimulation; Epilepsy; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium; N-Methylaspartate; Olfactory Bulb

1990
Neocortical epileptogenesis in vitro: studies with N-methyl-D-aspartate, phencyclidine, sigma and dextromethorphan receptor ligands.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:1

    Topics: Animals; Aspartic Acid; Carbachol; Cerebral Cortex; Dextromethorphan; Dose-Response Relationship, Drug; Epilepsy; In Vitro Techniques; Levorphanol; N-Methylaspartate; Potassium Channels; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma

1989
Action of anticonvulsants on hippocampal slices in Mg-free medium.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 339, Issue:6

    Topics: Animals; Anticonvulsants; Aspartic Acid; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Epilepsy; Hippocampus; In Vitro Techniques; Magnesium; N-Methylaspartate; Perfusion; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter

1989
NMDA antagonists differentiate epileptogenesis from seizure expression in an in vitro model.
    Science (New York, N.Y.), 1989, Aug-11, Volume: 245, Issue:4918

    Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Electrophysiology; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Valine

1989
Spontaneous epileptiform activity and alteration of GABA- and of NMDA-mediated neurotransmission in amygdala neurons kindled in vivo.
    Brain research, 1989, Aug-07, Volume: 494, Issue:1

    Topics: Animals; Aspartic Acid; Epilepsy; gamma-Aminobutyric Acid; In Vitro Techniques; Kindling, Neurologic; Male; N-Methylaspartate; Rats

1989
The NMDA receptor antagonist 2-amino-5-phosphonovalerate blocks stimulus train-induced epileptogenesis but not epileptiform bursting in the rat hippocampal slice.
    Journal of neurophysiology, 1987, Volume: 57, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Electric Stimulation; Electrophysiology; Epilepsy; Hippocampus; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine

1987
Effects of ketamine and (+)cyclazocine on 4-aminopyridine and "magnesium free" epileptogenic activity in hippocampal slices of rats.
    Neuropharmacology, 1987, Volume: 26, Issue:8

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cyclazocine; Epilepsy; Hippocampus; Ketamine; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Synaptic Transmission; Valine

1987
Epileptiform activity induced by alkalosis in rat neocortical slices: block by antagonists of N-methyl-D-aspartate.
    Neuroscience letters, 1987, Dec-29, Volume: 83, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Alkalosis; Animals; Aspartic Acid; Cerebral Cortex; Epilepsy; In Vitro Techniques; Ketamine; Magnesium Deficiency; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine

1987
Excitatory amino acid antagonists as novel anticonvulsants.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Amino Acids, Dicarboxylic; Animals; Anticonvulsants; Aspartic Acid; Epilepsy; Glutamates; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Nervous System Diseases; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Structure-Activity Relationship

1986
Evaluation of CPP, a selective NMDA antagonist, in various rodent models of epilepsy. Comparison with other NMDA antagonists, and with diazepam and phenobarbital.
    European journal of pharmacology, 1988, Jul-26, Volume: 152, Issue:1-2

    Topics: Amygdala; Animals; Anticonvulsants; Aspartic Acid; Diazepam; Electroshock; Epilepsy; Female; Gerbillinae; Kindling, Neurologic; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Phenobarbital; Piperazines; Psychomotor Performance; Rats; Time Factors

1988
Role of the substantia nigra in the kindling model of limbic epilepsy.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Animals; Aspartic Acid; Epilepsy; gamma-Aminobutyric Acid; Kindling, Neurologic; Limbic System; Muscimol; N-Methylaspartate; Rats; Substantia Nigra

1986
Long-term alterations in amino acid-induced ionic conductances in chronic epilepsy.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cobalt; Electric Conductivity; Epilepsy; Glutamates; Kainic Acid; Motor Cortex; N-Methylaspartate; Oxadiazoles; Pyramidal Tracts; Quisqualic Acid; Rats; Sodium

1986
Alterations in extracellular amino acids and Ca2+ following excitotoxin administration and during status epilepticus.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Amino Acids; Animals; Aspartic Acid; Bicuculline; Calcium; Epilepsy; Ethanolamines; Extracellular Space; Glutamates; Hippocampus; Kainic Acid; N-Methylaspartate; Rabbits; Synaptic Membranes; Synaptosomes; Taurine; Tetrodotoxin

1986
Excitatory amino acids and epilepsy-induced changes in extracellular space size.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Animals; Aspartic Acid; Cats; Epilepsy; Extracellular Space; Hippocampus; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuroglia; Oxadiazoles; Potassium; Quisqualic Acid; Somatosensory Cortex; Water-Electrolyte Balance

1986
Paradoxical anticonvulsant activity of the excitatory amino acid N-methyl-D-aspartate in the rat caudate-putamen.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:6

    Topics: Animals; Anticonvulsants; Aspartic Acid; Caudate Nucleus; Epilepsy; Ibotenic Acid; Male; N-Methylaspartate; Pilocarpine; Putamen; Rats; Rats, Inbred Strains; Substantia Nigra

1987