Page last updated: 2024-08-22

n-methylaspartate and Anxiety

n-methylaspartate has been researched along with Anxiety in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (12.12)18.2507
2000's10 (30.30)29.6817
2010's16 (48.48)24.3611
2020's3 (9.09)2.80

Authors

AuthorsStudies
Ganjkhani, M; Khosravi, M; Meftahi, GH; Rahimi, M; Sahraei, H; Sahraei, M1
Alijanpour, S; Farzamfard, P; Rezayof, A1
Baeta-Corral, R; De la Fuente, M; Giménez-Llort, L1
Feng, R; Liu, Q; Ma, F; Shen, S; Wang, F; Wang, Y; Wen, T; Xie, J1
Ahmadi, H; Nasehi, M; Rostami, P; Zarrindast, MR1
Chavan, JG; Salunke, BP; Umathe, SN1
Dudka, J; Oniszczuk, T; Poleszak, E; Serefko, A; Szopa, A; Wlaź, P; Wośko, S; Wróbel, A1
Aguiar, DC; Hott, SC; Moreira, FA; Resstel, LB; Viana, TG1
Herculano, AM; Lima, MG; Maximino, C; Miranda, V; Puty, B1
Fu, Q; Liu, X; Wang, Y; Zhao, S1
Pitsikas, N; Touzlatzi, N; Trevlopoulou, A1
Bertoglio, LJ; Carobrez, AP; Moraes, CL1
Miguel, TT; Nunes-de-Souza, RL1
Mendes-Gomes, J; Nunes-de-Souza, RL1
Moto, FC; Ngo Bum, E; Ngoupaye, GT; Nkantchoua, GC; Pelanken, MM; Rakotonirina, A; Rakotonirina, SV; Taiwe, GS1
Motevasseli, T; Nayer-Nouri, T; Rezayof, A; Zarrindast, MR1
Aou, S; Masuda, A1
Amaral, VC; Mendes-Gomes, J; Nunes-de-Souza, RL1
Ayissi Mbomo, R; Gartside, S; McQuade, R; Ngo Bum, E; Njikam, N; Okello, E1
Aghamohammadi-Sereshki, A; Rezayof, A; Rostami, P; Zarrindast, MR1
Greene, JS; Greig, NH; Jimenez, DV; Lu, B; Lu, Y; Manji, HK; Martinowich, K; Paredes, D; Schloesser, RJ1
Bavaresco, DV; Boeck, CR; Comim, CM; Damiani-Neves, M; Moojen, VK; Pescador, BB; Quevedo, J1
Bizot, JC; Boulouard, M; Burgo, A; Contremoulins, V; Danglot, L; Dauphin, F; Freret, T; Galli, T; Gaspar, P; Hyenne, V; Le Roux, N; Narboux Nême, N; Poncer, JC; Roumier, A; Simmler, MC; Vodjdani, G1
Coimbra, NC; Maisonnette, SS; Strauss, CV; Zangrossi, H1
Deacon, RM; Penny, C; Rawlins, JN1
Adamantidis, A; Coumans, B; Foidart, A; Grisar, T; Lakaye, B; Minet, A; Seutin, V; Thomas, E; Tirelli, E; Tyhon, A1
Cao, H; Guo, JD; Ji, RR; Ren, WH; Sha, H; Wang, H; Wang, PF; Zhang, YQ; Zhao, ZQ1
Bertoglio, LJ; Zangrossi, H1
Colwell, DD; Kavaliers, M1
Wiley, JL1
Franklin, KB; Leri, F2
Adamec, RE1

Reviews

1 review(s) available for n-methylaspartate and Anxiety

ArticleYear
Behavioral pharmacology of N-methyl-D-aspartate antagonists: implications for the study and pharmacotherapy of anxiety and schizophrenia.
    Experimental and clinical psychopharmacology, 1997, Volume: 5, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior; Behavior, Animal; Excitatory Amino Acid Antagonists; Humans; N-Methylaspartate; Schizophrenia; Schizophrenic Psychology

1997

Other Studies

32 other study(ies) available for n-methylaspartate and Anxiety

ArticleYear
Anxiogenic and anxiolytic effects of memantine injected into the ventral hippocampus in male stressed mice.
    Journal of complementary & integrative medicine, 2022, Sep-01, Volume: 19, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Hippocampus; Male; Memantine; Mice; N-Methylaspartate; Stainless Steel

2022
Ventral hippocampal NMDA receptors mediate the effects of nicotine on stress-induced anxiety/exploratory behaviors in rats.
    Neuroscience letters, 2022, 05-29, Volume: 780

    Topics: Animals; Anxiety; Exploratory Behavior; Hippocampus; Male; N-Methylaspartate; Nicotine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

2022
Sex-dependent worsening of NMDA-induced responses, anxiety, hypercortisolemia, and organometry of early peripheral immunoendocrine impairment in adult 3xTg-AD mice and their long-lasting ontogenic modulation by neonatal handling.
    Behavioural brain research, 2023, 02-13, Volume: 438

    Topics: Alzheimer Disease; Animals; Anxiety; Corticosterone; Disease Models, Animal; Female; Male; Mice; Mice, Transgenic; N-Methylaspartate

2023
Dcf1 Affects Memory and Anxiety by Regulating NMDA and AMPA Receptors.
    Neurochemical research, 2019, Volume: 44, Issue:11

    Topics: Animals; Anxiety; Dendritic Spines; Gene Knockout Techniques; Hippocampus; Male; Membrane Proteins; Memory; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses

2019
Involvement of the nucleus accumbens shell dopaminergic system in prelimbic NMDA-induced anxiolytic-like behaviors.
    Neuropharmacology, 2013, Volume: 71

    Topics: Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopaminergic Neurons; Dose-Response Relationship, Drug; Exploratory Behavior; Injections, Intraventricular; Male; N-Methylaspartate; Nerve Tissue Proteins; Nucleus Accumbens; Protein Isoforms; Random Allocation; Rats; Rats, Wistar; Receptors, Dopamine

2013
Involvement of NMDA receptor in low-frequency magnetic field-induced anxiety in mice.
    Electromagnetic biology and medicine, 2014, Volume: 33, Issue:4

    Topics: Animals; Anxiety; Bicuculline; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Magnetic Fields; Male; Maze Learning; Mice; Muscimol; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Social Behavior; Time Factors

2014
NMDA receptor activation antagonizes the NMDA antagonist-induced antianxiety effect in the elevated plus-maze test in mice.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Binding Sites; Brain; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ligands; Male; Maze Learning; Mice; N-Methylaspartate; Quinolones; Receptors, N-Methyl-D-Aspartate; Serine

2013
Anti-aversive role of the endocannabinoid system in the periaqueductal gray stimulation model of panic attacks in rats.
    Psychopharmacology, 2015, Volume: 232, Issue:9

    Topics: Amidohydrolases; Animals; Anxiety; Arachidonic Acids; Behavior, Animal; Benzamides; Carbamates; Disease Models, Animal; Endocannabinoids; Enzyme Inhibitors; Male; N-Methylaspartate; Panic Disorder; Periaqueductal Gray; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1

2015
Interactions between serotonin and glutamate-nitric oxide pathways in zebrafish scototaxis.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 129

    Topics: 5-Hydroxytryptophan; Animals; Anxiety; Glutamic Acid; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Piperazines; Pyridines; Serotonin; Zebrafish

2015
Effects of the medial or basolateral amygdala upon social anxiety and social recognition in mice.
    Turkish journal of medical sciences, 2014, Volume: 44, Issue:3

    Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Brain Diseases; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Recognition, Psychology

2014
The nitric oxide donor sodium nitroprusside attenuates recognition memory deficits and social withdrawal produced by the NMDA receptor antagonist ketamine and induces anxiolytic-like behaviour in rats.
    Psychopharmacology, 2016, Volume: 233, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Excitatory Amino Acid Antagonists; Ketamine; Male; Memory Disorders; Motor Activity; N-Methylaspartate; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Social Behavior

2016
Interplay between glutamate and serotonin within the dorsal periaqueductal gray modulates anxiety-related behavior of rats exposed to the elevated plus-maze.
    Behavioural brain research, 2008, Dec-12, Volume: 194, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Maze Learning; N-Methylaspartate; Periaqueductal Gray; Piperazines; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2008
Anxiogenic-like effects induced by NMDA receptor activation are prevented by inhibition of neuronal nitric oxide synthase in the periaqueductal gray in mice.
    Brain research, 2008, Nov-13, Volume: 1240

    Topics: Animals; Anxiety; Behavior, Animal; Enzyme Inhibitors; Injections, Intraventricular; Mice; Microinjections; Motor Activity; N-Methylaspartate; Nitric Oxide Synthase Type I; Periaqueductal Gray; Receptors, N-Methyl-D-Aspartate

2008
Anxiolytic-like effects produced by bilateral lesion of the periaqueductal gray in mice: Influence of concurrent nociceptive stimulation.
    Behavioural brain research, 2009, Nov-05, Volume: 203, Issue:2

    Topics: Animals; Anxiety; Exploratory Behavior; Male; Mice; N-Methylaspartate; Pain; Pain Measurement; Periaqueductal Gray

2009
Anticonvulsant, anxiolytic, and sedative properties of the roots of Nauclea latifolia Smith in mice.
    Epilepsy & behavior : E&B, 2009, Volume: 15, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Cameroon; Convulsants; Diazepam; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Agonists; Fever; Hypnotics and Sedatives; Male; Mice; Motor Activity; N-Methylaspartate; Pentylenetetrazole; Plant Roots; Rubiaceae; Seizures; Sleep; Stress, Psychological; Strychnine

2009
Role of ventral hippocampal NMDA receptors in anxiolytic-like effect of morphine.
    Physiology & behavior, 2010, Dec-02, Volume: 101, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Mice; Microinjections; Morphine; Motor Activity; N-Methylaspartate; Narcotics; Receptors, N-Methyl-D-Aspartate

2010
Lesions of the medial prefrontal cortex enhance social modulation of avoidance.
    Behavioural brain research, 2011, Mar-01, Volume: 217, Issue:2

    Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Disease Models, Animal; Exploratory Behavior; Inhibition, Psychological; Male; Maze Learning; N-Methylaspartate; Prefrontal Cortex; Rats; Rats, Wistar; Reaction Time; Social Behavior; Time Factors

2011
Ventrolateral periaqueductal gray lesion attenuates nociception but does not change anxiety-like indices or fear-induced antinociception in mice.
    Behavioural brain research, 2011, Jun-01, Volume: 219, Issue:2

    Topics: Animals; Anxiety; Behavior, Animal; Excitatory Amino Acid Agonists; Fear; Formaldehyde; Male; Maze Learning; Mice; N-Methylaspartate; Nociceptors; Pain; Pain Measurement; Periaqueductal Gray

2011
Effect of Mimosa pudica (Linn.) extract on anxiety behaviour and GABAergic regulation of 5-HT neuronal activity in the mouse.
    Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anxiety; Diazepam; GABA Modulators; Isoxazoles; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mimosa; N-Methylaspartate; Phytotherapy; Plant Extracts; Raphe Nuclei; Receptors, GABA-A; Serotonin

2012
Nicotine-induced anxiogenic-like behaviours of rats in the elevated plus-maze: possible role of NMDA receptors of the central amygdala.
    Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Anxiety; Male; Maze Learning; N-Methylaspartate; Nicotine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

2012
Roles of p75(NTR), long-term depression, and cholinergic transmission in anxiety and acute stress coping.
    Biological psychiatry, 2012, Jan-01, Volume: 71, Issue:1

    Topics: Acetylcholine; Adaptation, Psychological; Analysis of Variance; Animals; Anxiety; Biophysics; Cholinergic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Exploratory Behavior; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Microinjections; N-Methylaspartate; Patch-Clamp Techniques; Proto-Oncogene Proteins c-fos; Receptors, Nerve Growth Factor; Stress, Psychological; Time Factors

2012
NMDA preconditioning prevents object recognition memory impairment and increases brain viability in mice exposed to traumatic brain injury.
    Brain research, 2012, Jul-23, Volume: 1466

    Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Brain Injuries; Cell Survival; Depression; Hippocampus; Male; Memory Disorders; Mice; Motor Activity; N-Methylaspartate; Permeability; Recognition, Psychology; Visual Perception

2012
Vezatin is essential for dendritic spine morphogenesis and functional synaptic maturation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Jun-27, Volume: 32, Issue:26

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Anxiety; Avoidance Learning; Cadherins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Carrier Proteins; Cells, Cultured; Conditioning, Psychological; Dendritic Spines; Electric Stimulation; Embryo, Mammalian; Excitatory Postsynaptic Potentials; Exploratory Behavior; Eye Proteins; Fear; Gene Expression Regulation; Glutamate Decarboxylase; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Male; Maze Learning; Membrane Proteins; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Microtubule-Associated Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurogenesis; Neurons; Receptors, AMPA; RNA, Messenger; Silver Staining; Statistics, Nonparametric; Synapses; Synaptosomes; Transfection; Vesicle-Associated Membrane Protein 2

2012
Effects of N-methyl-D-aspartate-induced amygdala lesion in rats submitted to the elevated T-maze test of anxiety.
    Physiology & behavior, 2003, Volume: 78, Issue:1

    Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Excitatory Amino Acid Agonists; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar

2003
Effects of medial prefrontal cortex cytotoxic lesions in mice.
    Behavioural brain research, 2003, Feb-17, Volume: 139, Issue:1-2

    Topics: Animals; Anxiety; Behavior, Animal; Cytotoxins; Exploratory Behavior; Feeding Behavior; Female; Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Microinjections; Motor Activity; N-Methylaspartate; Prefrontal Cortex; Sex Characteristics

2003
Disrupting the melanin-concentrating hormone receptor 1 in mice leads to cognitive deficits and alterations of NMDA receptor function.
    The European journal of neuroscience, 2005, Volume: 21, Issue:10

    Topics: Animals; Anxiety; Avoidance Learning; Electroshock; Exploratory Behavior; Gene Deletion; Habituation, Psychophysiologic; Hippocampus; In Situ Hybridization; Mice; Mice, Knockout; N-Methylaspartate; Pyramidal Cells; Receptors, Somatostatin; Tetrodotoxin

2005
Is endogenous D-serine in the rostral anterior cingulate cortex necessary for pain-related negative affect?
    Journal of neurochemistry, 2006, Volume: 96, Issue:6

    Topics: Animals; Anxiety; D-Amino-Acid Oxidase; Excitatory Amino Acid Antagonists; Fear; Glycine; Gyrus Cinguli; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Organ Culture Techniques; Pain; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Stress, Psychological; Synaptic Transmission

2006
Involvement of dorsolateral periaqueductal gray N-methyl-D-aspartic acid glutamate receptors in the regulation of risk assessment and inhibitory avoidance behaviors in the rat elevated T-maze.
    Behavioural pharmacology, 2006, Volume: 17, Issue:7

    Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Anxiety; Ethosuximide; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Fear; Hippocampus; Male; Microinjections; N-Methylaspartate; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Risk-Taking

2006
Decreased predator avoidance in parasitized mice: neuromodulatory correlates.
    Parasitology, 1995, Volume: 111 ( Pt 3)

    Topics: Animals; Anxiety; Avoidance Learning; Bicuculline; Cats; Coccidiosis; Dizocilpine Maleate; Eimeria; Flumazenil; GABA Antagonists; GABA-A Receptor Antagonists; Male; Mice; N-Methylaspartate; Naloxone; Odorants; Picrotoxin; Predatory Behavior; Receptors, GABA-A

1995
Learning impairments caused by lesions to the pedunculopontine tegmental nucleus: an artifact of anxiety?
    Brain research, 1998, Oct-05, Volume: 807, Issue:1-2

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Artifacts; Diazepam; Learning Disabilities; Male; Maze Learning; Memory Disorders; N-Methylaspartate; Pons; Rats; Rats, Long-Evans

1998
Evidence that NMDA-dependent limbic neural plasticity in the right hemisphere mediates pharmacological stressor (FG-7142)-induced lasting increases in anxiety-like behavior: study 3--the effects on amygdala efferent physiology of block of NMDA receptors p
    Journal of psychopharmacology (Oxford, England), 1998, Volume: 12, Issue:3

    Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Carbolines; Cats; Electrodes, Implanted; Evoked Potentials; Flumazenil; Functional Laterality; GABA Antagonists; GABA Modulators; Limbic System; Long-Term Potentiation; Male; N-Methylaspartate; Neuronal Plasticity; Neurons, Efferent; Receptors, N-Methyl-D-Aspartate; Vocalization, Animal

1998
Diazepam modifies the effect of pedunculopontine lesions on morphine but not on amphetamine conditioned place preference.
    Behavioural brain research, 2000, Dec-20, Volume: 117, Issue:1-2

    Topics: Amphetamine; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Brain Injuries; Central Nervous System Stimulants; Conditioning, Psychological; Diazepam; Excitatory Amino Acid Agonists; Male; Maze Learning; Morphine; N-Methylaspartate; Narcotics; Rats; Rats, Long-Evans; Tegmentum Mesencephali

2000