Page last updated: 2024-08-22

n-methylaspartate and Anoxemia

n-methylaspartate has been researched along with Anoxemia in 97 studies

Research

Studies (97)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (3.09)	18.7374
1990's	41 (42.27)	18.2507
2000's	31 (31.96)	29.6817
2010's	18 (18.56)	24.3611
2020's	4 (4.12)	2.80

Authors

Authors	Studies
Baron, BM; Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM; Staeger, MA	1
Behar-Cohen, F; Bigot, K; Bordet, T; Fan, Y; Inman, DM; Jaworski, T; Kodati, B; Nsiah, NY; Pappenhagen, N; Picard, E; Youale, J	1
Bär, J; Gomes, GM; Karpova, A; Kreutz, MR	1
Dariyerli, N; Ekiz-Yilmaz, T; Guner, I; Meydanlı, EEG; Sahin, G; Sönmez, D; Sönmez, OF; Yaman, MO; Yelmen, N	1
Li, CH; Liu, YZ	1
Hu, L; Liu, M; Pan, S; Pei, L; Shang, Y; Song, L; Wu, Y; Xian, W; Xiong, W; Yao, S	1
Bonny, C; Courtney, MJ; Ginet, V; Li, LL; Liu, X; Mathieu, M; Puyal, J; Truttmann, AC; Tuittila, M; Vergun, O	1
Haddad, JJ	1
Kononov, AV; Turovskaya, MV; Turovsky, EA; Zinchenko, VP	1
Carr, JA; Fu, Z; Go, A; Pamenter, ME; Powell, FL; Reid, SG	1
Chiarugi, A; Gerace, E; Landucci, E; Moroni, F; Pellegrini-Giampietro, DE; Scartabelli, T	1
Bonner, HP; Chen, G; D'Orsi, B; Düssmann, H; Engel, T; Henshall, DC; Kilbride, SM; Perez Alvarez, S; Pfeiffer, S; Plesnila, N; Prehn, JH	1
Kim, HJ; Kim, SW; Lee, HK; Lee, JK; Yoon, SH	1
Cunningham, CJ; Liu, X; Patel, KP; Sharma, NM; Zheng, H	1
Huang, J; Ji, ES; Liu, Y; Tamisier, R; Tong, J; Weiss, JW; Xiang, S	1
Hulse, RE; Kraig, RP; Kunkler, PE; Swenson, WG; White, DM	1
Cheng, ZJ; Gozal, D; Harden, SW; Li, L; Lin, Y; Wead, WB; Wurster, RD; Yan, B	1
Cui, HS; Hori, H; Matsumoto, K; Murakami, Y; Obi, R; Zhao, Q	1
Feinstein, DL; Kalinin, S; Leza, JC; Madrigal, JL; Polak, P	1
Mahmoudian, M; Rahbar-Roshandel, N; Rahimi-Moghaddam, P; Tavakoli-Far, B	1
Barrett, T; Chow, N; Deane, R; Fernández, JA; Griffin, JH; Guo, H; Singh, I; Wang, Y; Zlokovic, BV	1
Belyakov, AV; Samoilov, MO; Semenov, DG	1
Han, PL; Jeong, JY; Kim, HJ; Kim, SW; Lee, JK; Seo, JS; Yoon, SH	1
D'Arcangelo, G; Frank, C; Grossi, D; Luly, P; Rufini, S; Tancredi, V	1
Han, T; Li, J; Liang, P; Liu, T; Liu, X; Liu, XY; Su, P; Wang, KW; Wang, Y; Yin, DM; Zhang, B; Zhang, Y; Zhou, Z; Zhu, YB	1
Anrather, J; Chan, J; Coleman, CG; Delagrammatikas, GJ; Iadecola, C; Park, L; Pickel, VM; Wang, G; Zhou, J	1
Gheshmy, A; Manga, J; McAneney, J; Reid, SG	1
Dave, KR; Pileggi, A; Raval, AP	1
Bai, Y; Chen, L; Li, L; Qi, J; Qi, Z; Sun, K; Yang, R; Zhang, Z; Zhou, L	1
Elbrønd-Bek, H; Jørgensen, SH; Kelly, NM; Weidner, MS; Wellejus, A	1
Arbeloa, J; Gottlieb, M; Matute, C; Pérez-Samartín, A	1
Colombari, E; De Paula, PM; Menani, JV; Moreira, TS; Takakura, AC	1
Lobner, D	1
Rubaj, A; Sieklucka-Dziuba, M; Zgodziński, W	1
Kawasaki, K; Ogawa, S	1
Cimarosti, H; Geyer, AB; Horn, AP; Netto, CA; Rodnight, R; Salbego, CG; Tavares, A; Valentim, LM	1
Chai, CY; Hong, LZ	1
Brunette, E; Comas, T; Monette, R; Morley, P; Tauskela, JS	1
Buddle, M; Ciminello, LH; DiPasquale, K; Eberhardt, E; Levin, T; Raley-Susman, KM; Wing, R	1
Dasgupta, S; Deshpande, SB; Jha, A	1
Bicker, G; Paquet-Durand, F	1
Goraca, A	1
Andreasson, KA; Li, H; McCullough, LD; Pin, S; Wang, MM; Zeng, Z	1
Gheshmy, A; McAneney, J; Reid, SG; Uthayalingam, S	1
Hong, SS; Qian, H; Xia, Y; Zhang, J; Zhao, P	1
Alberi, S; Hakkoum, D; Muller, D; Quintana, P	1
Brunette, E; Hewitt, M; Mealing, G; Morley, P; Tauskela, JS	1
Dirnagl, U; Freyer, D; Lam, TT; Ruscher, K; Rzeczinski, S; Thein, E; Victorov, IV	1
Ballanyi, K; Secchia, L; Taccola, G	1
Heine, MF; Payne, RS; Rigor, BM; Schurr, A	1
Rauca, C; Rüthrich, HL	1
Davolio, C; Greenamyre, JT	1
Evrard, P; Gadisseux, JF; Gressens, P; Marret, S; Mukendi, R	1
Evrard, P; Gadisseux, JF; Gressens, P; Marret, S	1
Beal, MF; Finklestein, S; Henshaw, R; Kirschner, PB; Schulz, JB; Trubetskoy, V; Weise, J	1
Benicourt, C; Junien, JL; Lockhart, BP; Privat, A; Soulard, P	1
Canhão, P; de Mendonça, A; Ribeiro, JA	1
Brooks, KJ; Kauppinen, RA	1
Lazarewicz, JW; Salińska, E	1
Inoue, O; Nishizawa, K; Saito, Y; Suzuki, A	1
Panizzon, KL; Wallis, RA	1
Beal, MF; Finklestein, SP; Nozaki, K	1
Chiou, AL; Lin, JC; Wang, Y; Yang, ST	1
Katsuta, K; Kinoshita, T; Kuno, A; Nakanishi, H; Ohkubo, M; Shirakawa, K; Takasugi, H; Ueda, Y	1
Bari, F; Busija, DW; Errico, RA; Louis, TM	1
Caprioli, J; Kitano, S; Morgan, J	1
Frenguelli, BG	1
Akaike, N; Jin, YH; Koyama, S	1
Hunter, AJ; Rogers, DC	1
Hsu, KS; Huang, CC	1
Bari, F; Busija, DW; Louis, TM; Thore, CR	1
Kapin, MA; Opitz, T; Reyes, A; Reyes, M; Stanton, PK	1
Barnes, JR; Raley-Susman, KM	1
Hayase, Y; Higashiyama, S; Ohno, M; Sasahara, M; Shimada, M; Tanaka, N	1
Gwag, BJ; Kim, EY; Kim, H; Seo, SY	1
Bialobok, P; Cregan, EF; Hudzik, TJ; McCarthy, DJ; Palmer, GC; Sydserff, SG	1
Chatten-Brown, J; Hye, SE; Monje, ML; Raley-Susman, KM	1
Anderson, TR; Andrew, RD; Jarvis, CR	1
Anthony, DC; Iannotti, F; Johns, P; Niyadurupola, N; Pringle, AK	1
Haller, M; Mironov, SL; Richter, DW	1
Bernardi, G; Bonsi, P; Calabresi, P; Centonze, D; Pisani, A; Saulle, E; Tropepi, D	1
Nicklas, WJ; Zeevalk, GD	2
el-Asrar, AM; Maimone, D; Morse, PH; Reder, AT; Torczynski, E	1
Borosky, SA; Clissold, DB; Ferkany, JW; Goode, S; Karbon, EW; Patch, RJ; Pontecorvo, MJ	1
Carter, AJ; Müller, RE	1
Rigor, BM; Schurr, A; West, CA	1
Porsche, E; Schwan, T	1
Himori, N; Martin, JR; Moreau, JL	1
Bommarito, M; Johnston, MV; McDonald, JW; Silverstein, FS	1
Choi, DW	2
Hayakawa, T; Kinoshita, A; Kohmura, E; Matsumoto, K; Mogami, H; Yamada, K	1
Attwell, D; Barbour, B; Szatkowski, M	1
Ben-Ari, Y; Cherubini, E; Krnjević, K	1
Chambers, G; Cottrell, JE; Kass, IS	1
Arcavi, LJ; Ferriero, DM; McIntosh, TK; Sagar, SM; Simon, RP	1

Reviews

4 review(s) available for n-methylaspartate and Anoxemia

Article	Year
The bioanalytical molecular pharmacology of the N-methyl-D-aspartate (NMDA) receptor nexus and the oxygen-responsive transcription factor HIF-1α: putative mechanisms and regulatory pathways unravel the intimate hypoxia connection. Current molecular pharmacology, 2013, Volume: 6, Issue:2 Topics: Animals; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Models, Molecular; N-Methylaspartate; Protein Interaction Maps; Receptors, N-Methyl-D-Aspartate; Signal Transduction	2013
The low-affinity, use-dependent NMDA receptor antagonist AR-R 15896AR. An update of progress in stroke. Annals of the New York Academy of Sciences, 1999, Volume: 890 Topics: Animals; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Humans; Hypoxia; Ischemia; Mice; N-Methylaspartate; Neuroprotective Agents; Pyridines; Rats; Rats, Inbred SHR; Receptors, N-Methyl-D-Aspartate	1999
Cerebral hypoxia: some new approaches and unanswered questions. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:8 Topics: Animals; Aspartic Acid; Brain Diseases; Cell Survival; Cerebrovascular Circulation; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Hypoxia; N-Methylaspartate; Neuroglia; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1990
Possible mechanisms limiting N-methyl-D-aspartate receptor overactivation and the therapeutic efficacy of N-methyl-D-aspartate antagonists. Stroke, 1990, Volume: 21, Issue:11 Suppl Topics: Adenosine; Animals; Brain Ischemia; Calcium; Glutamates; Hydrogen-Ion Concentration; Hypoxia; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Zinc	1990

Other Studies

93 other study(ies) available for n-methylaspartate and Anoxemia

Article	Year
2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents. Journal of medicinal chemistry, 1990, Volume: 33, Issue:10 Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Gerbillinae; Hippocampus; Hypoxia; Male; Mice; Neurons; Phencyclidine; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Triazoles	1990
Neuroprotective Effects of Transferrin in Experimental Glaucoma Models. International journal of molecular sciences, 2022, Oct-22, Volume: 23, Issue:21 Topics: Animals; Disease Models, Animal; Glaucoma; Hypoxia; Intraocular Pressure; Iron; N-Methylaspartate; Neuroprotective Agents; Ocular Hypertension; Rats; Transferrin	2022
A Jacob/nsmf gene knockout does not protect against acute hypoxia- and NMDA-induced excitotoxic cell death. Molecular brain, 2023, 02-11, Volume: 16, Issue:1 Topics: Animals; Cell Death; Gene Knockout Techniques; Glucose; Hypoxia; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Oxygen; Receptors, N-Methyl-D-Aspartate; Synapses; Transcription Factors	2023
The role of NMDA glutamate receptors in lung injury caused by chronic long-term intermittent hypobaric hypoxia. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2023, Volume: 56 Topics: Animals; Dizocilpine Maleate; Glutamic Acid; Hypoxia; Interleukin-6; Lung Injury; N-Methylaspartate; Oxidants; Oxidative Stress; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tumor Necrosis Factor-alpha	2023
[Glutamate and its ionotropic receptor agonists inhibit the response to acute hypoxia in carotid body of rats]. Sheng li xue bao : [Acta physiologica Sinica], 2023, Aug-25, Volume: 75, Issue:4 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Dioxide; Carotid Body; Glutamic Acid; Hypoxia; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	2023
DAPK1-ERK signal mediates oxygen glucose deprivation reperfusion induced apoptosis in mouse N2a cells. Journal of the neurological sciences, 2018, 04-15, Volume: 387 Topics: Animals; Apoptosis; Cell Line, Tumor; Cerebral Cortex; Cytarabine; Death-Associated Protein Kinases; Disease Models, Animal; Excitatory Amino Acid Agonists; Glucose; Glycine; Hypoxia; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroblastoma; Neurons; Protein Biosynthesis; RNA, Small Interfering	2018
The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, May-08, Volume: 33, Issue:19 Topics: Adaptor Proteins, Signal Transducing; Analysis of Variance; Animals; Animals, Newborn; Brain; Calcium; Cell Death; Cells, Cultured; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Green Fluorescent Proteins; Humans; Hypoxia; Intracellular Signaling Peptides and Proteins; L-Lactate Dehydrogenase; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nitric Oxide Synthase Type I; p38 Mitogen-Activated Protein Kinases; Peptides; Protein Conformation; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Signal Transduction; Transfection	2013
Short-term episodes of hypoxia induce posthypoxic hyperexcitability and selective death of GABAergic hippocampal neurons. Experimental neurology, 2013, Volume: 250 Topics: Animals; Apoptosis; Calcium; Cell Hypoxia; Cell Survival; Excitatory Amino Acids; GABAergic Neurons; Hippocampus; Hypoxia; Immunohistochemistry; Interleukin-10; Ischemic Preconditioning; N-Methylaspartate; Rats; Signal Transduction	2013
Glutamate receptors in the nucleus tractus solitarius contribute to ventilatory acclimatization to hypoxia in rat. The Journal of physiology, 2014, Apr-15, Volume: 592, Issue:8 Topics: Acclimatization; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chemoreceptor Cells; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hypoxia; Male; N-Methylaspartate; Pulmonary Ventilation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reflex; Solitary Nucleus	2014
Interplay between histone acetylation/deacetylation and poly(ADP-ribosyl)ation in the development of ischemic tolerance in vitro. Neuropharmacology, 2015, Volume: 92 Topics: Acetylation; Animals; Animals, Newborn; Butyric Acid; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glucose; Hippocampus; Histones; Hydroxamic Acids; Hypoxia; In Vitro Techniques; N-Methylaspartate; Neurons; Organ Culture Techniques; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Signal Transduction; Time Factors; Vorinostat	2015
Bax regulates neuronal Ca2+ homeostasis. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Jan-28, Volume: 35, Issue:4 Topics: Animals; bcl-2-Associated X Protein; Calcium; Calcium Signaling; Cell Death; Cell Line, Tumor; Cells, Cultured; Embryo, Mammalian; Endoplasmic Reticulum; Excitatory Amino Acid Agonists; Extracellular Fluid; Glucose; Homeostasis; Hypoxia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; N-Methylaspartate; Neocortex; Neurons	2015
Neuroprotective effect of ethyl pyruvate against Zn(2+) toxicity via NAD replenishment and direct Zn(2+) chelation. Neuropharmacology, 2016, Volume: 105 Topics: Animals; Cell Death; Chelating Agents; Glucose; Hypoxia; N-Methylaspartate; NAD; Neurons; Neuroprotective Agents; Poly (ADP-Ribose) Polymerase-1; Primary Cell Culture; Pyruvates; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Zinc	2016
Hypoxia-Inducible Factor-1α Mediates Increased Sympathoexcitation via Glutamatergic N-Methyl-d-Aspartate Receptors in the Paraventricular Nucleus of Rats With Chronic Heart Failure. Circulation. Heart failure, 2016, Volume: 9, Issue:11 Topics: Animals; Cell Line; Chromatin Immunoprecipitation; Chronic Disease; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Agonists; Heart Failure; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sympathetic Nervous System; Up-Regulation	2016
Exposure to cyclic intermittent hypoxia increases expression of functional NMDA receptors in the rat carotid body. Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 106, Issue:1 Topics: Adaptation, Physiological; Animals; Blotting, Western; Carotid Body; Carotid Sinus; Disease Models, Animal; Disks Large Homolog 4 Protein; Endothelin-1; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoxia; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; Tyrosine 3-Monooxygenase; Up-Regulation	2009
Monomeric IgG is neuroprotective via enhancing microglial recycling endocytosis and TNF-alpha. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Nov-19, Volume: 28, Issue:47 Topics: Animals; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Ectodysplasins; Endocytosis; Glucose; Hippocampus; Hypoxia; Immunoglobulin G; Interleukin-1beta; Lysosomal-Associated Membrane Protein 1; Microglia; Minocycline; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Phosphopyruvate Hydratase; rab GTP-Binding Proteins; Rats; Tumor Necrosis Factor-alpha	2008
Chronic intermittent hypoxia impairs heart rate responses to AMPA and NMDA and induces loss of glutamate receptor neurons in nucleus ambiguous of F344 rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baroreflex; Blood Pressure; Brain Stem; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Agonists; Heart; Heart Rate; Hypoxia; Microinjections; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Rats; Rats, Inbred F344; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate	2009
Berberine exerts neuroprotective actions against in vitro ischemia-induced neuronal cell damage in organotypic hippocampal slice cultures: involvement of B-cell lymphoma 2 phosphorylation suppression. Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:1 Topics: Animals; Berberine; Cell Death; Docosahexaenoic Acids; Excitatory Amino Acid Agonists; Glucose; Hippocampus; Hypoxia; Ischemia; Isoxazoles; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Organ Culture Techniques; Phosphorylation; Propidium; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Time Factors	2009
Astrocyte-derived MCP-1 mediates neuroprotective effects of noradrenaline. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Jan-07, Volume: 29, Issue:1 Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Astrocytes; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Chemokine CCL2; Coculture Techniques; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glucose; Glutamic Acid; Hypoxia; L-Lactate Dehydrogenase; Microglia; N-Methylaspartate; Neurons; Neuroprotective Agents; Norepinephrine; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transfection	2009
Neuroprotective effects of mebudipine and dibudipine on cerebral oxygen-glucose deprivation/reperfusion injury. European journal of pharmacology, 2009, May-21, Volume: 610, Issue:1-3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formazans; Glucose; Hypoxia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Quinoxalines; Receptors, Kainic Acid; Reperfusion Injury; Tetrazolium Salts; Time Factors	2009
Neuroprotective activities of activated protein C mutant with reduced anticoagulant activity. The European journal of neuroscience, 2009, Volume: 29, Issue:6 Topics: Analysis of Variance; Animals; Antibodies; Anticoagulants; Apoptosis; Brain; Caspase 3; Caspase 9; Cells, Cultured; Embryo, Mammalian; Endothelial Cells; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Glucose; Hemoglobins; Humans; Hypoxia; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; N-Methylaspartate; Neurons; Neuroprotective Agents; Pregnancy; Protein C; Receptors, Proteinase-Activated; Time Factors; Tumor Suppressor Protein p53	2009
Moderate hypobaric hypoxia modifies Ca2+-mediated glutamatergic signal transduction in rat cerebral cortex. Bulletin of experimental biology and medicine, 2009, Volume: 147, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebral Cortex; Excitatory Amino Acid Agonists; Glutamic Acid; Hypoxia; Male; N-Methylaspartate; Rats; Rats, Wistar; Signal Transduction	2009
Combination treatment with ethyl pyruvate and aspirin enhances neuroprotection in the postischemic brain. Neurotoxicity research, 2010, Volume: 17, Issue:1 Topics: Animals; Aspirin; Astringents; Astrocytes; Brain Infarction; Cells, Cultured; Cerebral Cortex; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Embryo, Mammalian; Excitatory Amino Acid Agonists; Gene Expression Regulation; Glucose; Hypoxia; Infarction, Middle Cerebral Artery; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; NF-kappa B; Polysaccharides; Pyruvates; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Severity of Illness Index; Time Factors; Zinc Sulfate	2010
Cholesterol depletion inhibits electrophysiological changes induced by anoxia in CA1 region of rat hippocampal slices. Brain research, 2009, Nov-17, Volume: 1298 Topics: Action Potentials; Analysis of Variance; Animals; beta-Cyclodextrins; CA1 Region, Hippocampal; Cholesterol; Electrophysiology; Excitatory Postsynaptic Potentials; Glucose; Hypoxia; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurons; Organ Culture Techniques; Rats; Rats, Wistar; Time Factors	2009
The DREAM protein negatively regulates the NMDA receptor through interaction with the NR1 subunit. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Jun-02, Volume: 30, Issue:22 Topics: Analysis of Variance; Animals; Biotinylation; Brain Edema; Brain Infarction; Brain Ischemia; Cell Count; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Gene Expression Regulation; Glucose; Green Fluorescent Proteins; Hippocampus; Humans; Hypoxia; Immunoprecipitation; Kv Channel-Interacting Proteins; L-Lactate Dehydrogenase; Membrane Potentials; Mice; Mice, Inbred BALB C; Mutation; N-Methylaspartate; Neurons; Neuroprotective Agents; Oocytes; Patch-Clamp Techniques; Peptides; Protein Binding; Protein Transport; Rats; Receptors, N-Methyl-D-Aspartate; Repressor Proteins; RNA, Small Interfering; Time Factors; Transfection; Xenopus	2010
Chronic intermittent hypoxia induces NMDA receptor-dependent plasticity and suppresses nitric oxide signaling in the mouse hypothalamic paraventricular nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Sep-08, Volume: 30, Issue:36 Topics: Analysis of Variance; Animals; Arginine; Blood Gas Analysis; Blood Pressure; Cyclic N-Oxides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Hydrogen-Ion Concentration; Hypoxia; Imidazoles; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; N-Methylaspartate; Neuronal Plasticity; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Paraventricular Hypothalamic Nucleus; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Time Factors; Vasopressins	2010
Chronic hypoxia and chronic hypercapnia differentially regulate an NMDA-sensitive component of the acute hypercapnic ventilatory response in the cane toad (Rhinella marina). Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2011, Volume: 181, Issue:6 Topics: Animals; Bufo marinus; Dizocilpine Maleate; Hypercapnia; Hypoxia; N-Methylaspartate; Respiration; Respiratory Mechanics	2011
Recurrent hypoglycemia increases oxygen glucose deprivation-induced damage in hippocampal organotypic slices. Neuroscience letters, 2011, May-27, Volume: 496, Issue:1 Topics: Animals; Animals, Newborn; Cell Death; Excitatory Amino Acid Agonists; Glucose; Hippocampus; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Insulin; N-Methylaspartate; Neurons; Organ Culture Techniques; Oxygen; Rats; Time Factors	2011
Cerebroside-A provides potent neuroprotection after cerebral ischaemia through reducing glutamate release and Ca²⁺ influx of NMDA receptors. The international journal of neuropsychopharmacology, 2012, Volume: 15, Issue:4 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Brain Ischemia; Calcium; Cerebral Infarction; Cerebrosides; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Valine	2012
4-iodophenyl isothiocyanate: a neuroprotective compound. Restorative neurology and neuroscience, 2012, Volume: 30, Issue:1 Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Cells, Cultured; Cerebral Cortex; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Embryo, Mammalian; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glucose; Glutamic Acid; Herbicides; Hypoxia; Iodobenzenes; Isothiocyanates; L-Lactate Dehydrogenase; Monoamine Oxidase; N-Methylaspartate; Neurites; Neuroglia; Neurons; Neuroprotective Agents; Peroxides; Protein Binding; Rats; Rats, Wistar	2012
P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia. Neurobiology of disease, 2012, Volume: 45, Issue:3 Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Brain Injuries; Calcium; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Fluoresceins; Glucose; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Membrane Potentials; N-Methylaspartate; Neurologic Examination; Neurons; Organic Chemicals; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Purinergic P2X Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X7; Rosaniline Dyes; Tetrazolium Salts	2012
Control of breathing and blood pressure by parafacial neurons in conscious rats. Experimental physiology, 2013, Volume: 98, Issue:1 Topics: Animals; Blood Pressure; Consciousness; Hypercapnia; Hypoxia; Male; Muscimol; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Respiration; Respiratory Center	2013
Saturation of neuroprotective effects of adenosine in cortical culture. Neuroreport, 2002, Nov-15, Volume: 13, Issue:16 Topics: Adenosine; Animals; Cell Culture Techniques; Cell Death; Cerebral Cortex; Excitatory Amino Acid Agonists; Extracellular Space; Glucose; Hypoxia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline	2002
The epileptogenic effect of seizures induced by hypoxia: the role of NMDA and AMPA/KA antagonists. Pharmacology, biochemistry, and behavior, 2003, Volume: 74, Issue:2 Topics: Animals; Avoidance Learning; Bicuculline; Brain Chemistry; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hypoxia; Mice; N-Methylaspartate; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures	2003
[The role of glycine binding site in NMDA receptor--interactions between NMDA and D-serine in artificial anoxia/agycemia rat hippocampus]. Masui. The Japanese journal of anesthesiology, 2003, Volume: 52, Issue:1 Topics: Animals; Binding Sites; Glycine; Hippocampus; Hypoxia; In Vitro Techniques; N-Methylaspartate; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine	2003
Changes in heat shock protein 27 phosphorylation and immunocontent in response to preconditioning to oxygen and glucose deprivation in organotypic hippocampal cultures. Neuroscience, 2003, Volume: 118, Issue:2 Topics: Animals; Blotting, Western; Cell Death; Excitatory Amino Acid Agonists; Glucose; Heat-Shock Proteins; Hippocampus; HSP72 Heat-Shock Proteins; Hypoxia; Immunohistochemistry; Ischemic Preconditioning; N-Methylaspartate; Organ Culture Techniques; Oxygen; Phosphorylation; Rats; Rats, Wistar; Time Factors	2003
Involvement of N-methyl-D-aspartate receptors in post-hypoxic depression of the dorsomedial medulla in cats. Neuroscience letters, 2003, Jun-12, Volume: 343, Issue:3 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Gas Analysis; Blood Pressure; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Heart Rate; Hypoxia; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Spinal Nerves	2003
Preconditioning of cortical neurons by oxygen-glucose deprivation: tolerance induction through abbreviated neurotoxic signaling. American journal of physiology. Cell physiology, 2003, Volume: 285, Issue:4 Topics: 2,4-Dinitrophenol; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cerebral Cortex; Extracellular Space; Glucose; Glutamic Acid; Hypoxia; Ischemic Preconditioning; Mitochondria; N-Methylaspartate; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Uncoupling Agents	2003
Microtubule-associated protein 2 (MAP2) associates with the NMDA receptor and is spatially redistributed within rat hippocampal neurons after oxygen-glucose deprivation. Brain research, 2003, Jul-18, Volume: 978, Issue:1-2 Topics: Animals; Calcium; Calcium Channel Blockers; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glucose; Glycoproteins; Hippocampus; Hypoxia; Immunoblotting; Immunohistochemistry; In Vitro Techniques; Male; Microtubule-Associated Proteins; N-Methylaspartate; Neurons; Oxygen; Precipitin Tests; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors	2003
Effect of ischaemia & aglycaemia on the synaptic transmission in neonatal rat spinal cord in vitro. The Indian journal of medical research, 2003, Volume: 118 Topics: Animals; Animals, Newborn; Cell Hypoxia; Glucose; Glycine; Hypoxia; Ischemia; Magnesium; N-Methylaspartate; Oxygen; Perfusion; Rats; Spinal Cord; Spinal Nerve Roots; Synapses; Synaptic Transmission; Time Factors	2003
Hypoxic/ischaemic cell damage in cultured human NT-2 neurons. Brain research, 2004, Jun-11, Volume: 1011, Issue:1 Topics: Aging; Calcimycin; Calcium; Cell Death; Cell Line, Tumor; Cell Survival; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescein; Glutamic Acid; Humans; Hypoxia; Ionophores; Mitochondria; N-Methylaspartate; Neurons; Teratocarcinoma; Time Factors	2004
Oxytocin content in the venous blood outflowing from the vicinity of the cavernous sinus and from the femoral vein. Endocrine regulations, 2004, Volume: 38, Issue:3 Topics: Animals; Cavernous Sinus; Femoral Vein; Hypoxia; Male; N-Methylaspartate; Oxytocin; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	2004
Sex differences in cell death. Annals of neurology, 2005, Volume: 58, Issue:2 Topics: Animals; Animals, Newborn; Cell Death; Disease Models, Animal; DNA-Binding Proteins; Drug Interactions; Female; Genotype; Glucose; High Mobility Group Proteins; Hippocampus; Hypoxia; Indazoles; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Nitric Oxide; Organ Culture Techniques; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Characteristics; SOXB1 Transcription Factors; Stroke; Superoxide Dismutase; Time Factors; Transcription Factors	2005
Chronic hypoxia modulates NMDA-mediated regulation of the hypoxic ventilatory response in an amphibian, Bufo marinus. Respiratory physiology & neurobiology, 2006, Volume: 153, Issue:1 Topics: Acclimatization; Analysis of Variance; Animals; Bufo marinus; Cyanates; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hypoxia; N-Methylaspartate; Pulmonary Ventilation; Respiration; Time Factors	2006
Rapid hypoxia preconditioning protects cortical neurons from glutamate toxicity through delta-opioid receptor. Stroke, 2006, Volume: 37, Issue:4 Topics: Animals; Cells, Cultured; Cellular Senescence; Cerebral Cortex; Enkephalin, Leucine-2-Alanine; Glutamic Acid; Hypoxia; Ischemic Preconditioning; L-Lactate Dehydrogenase; N-Methylaspartate; Naltrexone; Narcotic Antagonists; Neurons; Rats; Receptors, Opioid, delta; RNA, Messenger; Time Factors; Up-Regulation	2006
Glutamate receptor changes associated with transient anoxia/hypoglycaemia in hippocampal slice cultures. The European journal of neuroscience, 2006, Volume: 23, Issue:4 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Blotting, Western; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Hippocampus; Hypoglycemia; Hypoxia; In Vitro Techniques; N-Methylaspartate; Patch-Clamp Techniques; Rats; Receptors, Glutamate; Time Factors	2006
Competing approaches to excitotoxic neuroprotection by inert and catalytic antioxidant porphyrins. Neuroscience letters, 2006, Jul-03, Volume: 401, Issue:3 Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Glucose; Hypoxia; Metalloporphyrins; N-Methylaspartate; Neurons; Neuroprotective Agents; Phosphatidylinositols; Rats	2006
Neuroprotective effects of the beta-carboline abecarnil studied in cultured cortical neurons and organotypic retinal cultures. Neuropharmacology, 2007, Volume: 52, Issue:7 Topics: Analysis of Variance; Animals; beta Carotene; Carbolines; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Glucose; Hypoxia; L-Lactate Dehydrogenase; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Organ Culture Techniques; Rats; Rats, Wistar; Retina	2007
Anoxic persistence of lumbar respiratory bursts and block of lumbar locomotion in newborn rat brainstem spinal cords. The Journal of physiology, 2007, Dec-01, Volume: 585, Issue:Pt 2 Topics: Abdominal Muscles; Action Potentials; Animals; Animals, Newborn; Cervical Vertebrae; Excitatory Amino Acid Agonists; Exhalation; Facial Nerve; Hypoglossal Nerve; Hypoxia; Inhalation; Locomotion; Lumbar Vertebrae; Medulla Oblongata; Motor Neurons; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Rats, Wistar; Respiratory Center; Serotonin; Spinal Cord; Stimulation, Chemical	2007
Hypoxia, excitotoxicity, and neuroprotection in the hippocampal slice preparation. Journal of neuroscience methods, 1995, Volume: 59, Issue:1 Topics: Animals; Dose-Response Relationship, Drug; Excitatory Amino Acids; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Glutamate	1995
Moderate hypoxia reduces pentylenetetrazol-induced seizures. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 351, Issue:3 Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Agents; Hypoxia; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Pentylenetetrazole; Receptors, Purinergic; Seizures; Time Factors; Xanthines	1995
Selective vulnerability of the CA1 region of hippocampus to the indirect excitotoxic effects of malonic acid. Neuroscience letters, 1995, Jun-02, Volume: 192, Issue:1 Topics: Animals; Autoradiography; Brain Ischemia; Dizocilpine Maleate; Hippocampus; Hypoxia; Hypoxia, Brain; Male; Malonates; N-Methylaspartate; Rats; Rats, Sprague-Dawley	1995
Effect of ibotenate on brain development: an excitotoxic mouse model of microgyria and posthypoxic-like lesions. Journal of neuropathology and experimental neurology, 1995, Volume: 54, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Alanine; Amino Acids; Animals; Brain; Brain Diseases; Embryonic and Fetal Development; Excitatory Amino Acids; Female; Glial Fibrillary Acidic Protein; Hypoxia; Ibotenic Acid; Male; Mice; N-Methylaspartate; Neurons; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate	1995
Prevention by magnesium of excitotoxic neuronal death in the developing brain: an animal model for clinical intervention studies. Developmental medicine and child neurology, 1995, Volume: 37, Issue:6 Topics: Animals; Brain Death; Cerebrovascular Circulation; Clinical Protocols; Female; Hypoxia; Ibotenic Acid; Injections, Intraperitoneal; Magnesium; Male; Mice; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate	1995
Basic fibroblast growth factor protects against excitotoxicity and chemical hypoxia in both neonatal and adult rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1995, Volume: 15, Issue:4 Topics: 1-Methyl-4-phenylpyridinium; Animals; Animals, Newborn; Cell Death; Excitatory Amino Acids; Fibroblast Growth Factor 2; Hypoxia; Male; Malonates; N-Methylaspartate; Nervous System Diseases; Neurons; Rats; Rats, Sprague-Dawley	1995
Distinct neuroprotective profiles for sigma ligands against N-methyl-D-aspartate (NMDA), and hypoxia-mediated neurotoxicity in neuronal culture toxicity studies. Brain research, 1995, Mar-27, Volume: 675, Issue:1-2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzofurans; Brain Ischemia; Cell Death; Cells, Cultured; Dizocilpine Maleate; Hypoxia; Kainic Acid; Ligands; N-Methylaspartate; Neurons; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Phencyclidine; Receptors, sigma	1995
1,3-Dipropyl-8-cyclopentylxanthine attenuates the NMDA response to hypoxia in the rat hippocampus. Brain research, 1994, Oct-24, Volume: 661, Issue:1-2 Topics: Animals; Evoked Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Male; N-Methylaspartate; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time Factors; Xanthines	1994
Calcium-mediated damage following hypoxia in cerebral cortex ex vivo studied by NMR spectroscopy. Evidence for direct involvement of voltage-gated Ca(2+)-channels. Neurochemistry international, 1993, Volume: 23, Issue:5 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Diltiazem; Excitatory Amino Acid Antagonists; Hydrogen; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Magnesium; Magnetic Resonance Spectroscopy; N-Methylaspartate; Neurons; Phosphocreatine; Phosphorus; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	1993
NMDA receptors mediate anoxia/aglycemia-induced release of eicosanoids in immature rat hippocampal slices: utility of an in vitro "ischemic" superfusion model with temporary arrest of medium flow. Folia neuropathologica, 1994, Volume: 32, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Brain Ischemia; Calcium; Culture Techniques; Dizocilpine Maleate; Eicosanoids; Hippocampus; Hypoxia; N-Methylaspartate; Quinacrine; Radioimmunoassay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Thromboxane B2	1994
Protective effects of kamikihi-to, a traditional Chinese medicine, against cerebral ischemia, hypoxia and anoxia in mice and gerbils. Japanese journal of pharmacology, 1994, Volume: 64, Issue:3 Topics: Animals; Brain Ischemia; Carotid Artery Diseases; Carotid Artery, Common; Cell Death; Drugs, Chinese Herbal; Gerbillinae; Hippocampus; Hypoxia; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Potassium Cyanide; Pyramidal Cells	1994
Protection from hypoxic and N-methyl-D-aspartate injury with azelastine, a leukotriene inhibitor. European journal of pharmacology, 1993, Jul-20, Volume: 238, Issue:2-3 Topics: Animals; Diphenhydramine; Electrophysiology; Hippocampus; Hypoxia; In Vitro Techniques; Leukotriene C4; Lipoxygenase Inhibitors; Male; Membrane Potentials; N-Methylaspartate; Phthalazines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1	1993
Basic fibroblast growth factor protects against hypoxia-ischemia and NMDA neurotoxicity in neonatal rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1993, Volume: 13, Issue:2 Topics: Animals; Animals, Newborn; Body Temperature; Brain; Brain Ischemia; Female; Fibroblast Growth Factor 2; Hypoxia; N-Methylaspartate; Pregnancy; Rats	1993
Ketamine antagonizes hypoxia-induced dopamine release in rat striatum. Brain research, 1995, Sep-25, Volume: 693, Issue:1-2 Topics: Animals; Blood Gas Analysis; Dopamine; Dopamine Antagonists; Electrochemistry; Hydrogen-Ion Concentration; Hypercapnia; Hypoxia; Ketamine; Microinjections; N-Methylaspartate; Neostriatum; Nitrogen; Potassium Chloride; Rats; Rats, Sprague-Dawley; Respiration; Tubocurarine	1995
Studies on cerebral protective agents. X. Synthesis and evaluation of anticonvulsant activities for novel 4,5,6,7-tetrahydrothieno[3,3-c]pyridines and related compounds. Chemical & pharmaceutical bulletin, 1996, Volume: 44, Issue:4 Topics: Animals; Anticonvulsants; Convulsants; Excitatory Amino Acid Agonists; Hypoxia; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Pyridines; Stereoisomerism; Structure-Activity Relationship; Thiophenes; X-Ray Diffraction	1996
Differential effects of short-term hypoxia and hypercapnia on N-methyl-D-aspartate-induced cerebral vasodilatation in piglets. Stroke, 1996, Volume: 27, Issue:9 Topics: Acute Disease; Animals; Animals, Newborn; Arterioles; Cerebrovascular Circulation; Female; Hypercapnia; Hypoxia; Male; N-Methylaspartate; Pia Mater; Vasodilation	1996
Hypoxic and excitotoxic damage to cultured rat retinal ganglion cells. Experimental eye research, 1996, Volume: 63, Issue:1 Topics: Animals; Astrocytes; Cell Culture Techniques; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamic Acid; Hypoxia; N-Methylaspartate; Neuroglia; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Time Factors	1996
The effects of metabolic stress on glutamate receptor-mediated depolarizations in the in vitro rat hippocampal slice. Neuropharmacology, 1997, Volume: 36, Issue:7 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Hippocampus; Hypoxia; In Vitro Techniques; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Glutamate; Stress, Physiological; Synaptic Transmission	1997
Functional interaction between Na(+)-K+ pump and KATP channels in the CNS neurons under experimental brain ischemia. The Japanese journal of physiology, 1997, Volume: 47 Suppl 1 Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Calcium; Cytosol; Electric Conductivity; Excitatory Amino Acid Agonists; Hypoglycemia; Hypoxia; Locus Coeruleus; N-Methylaspartate; Neurons; Osmolar Concentration; Potassium Channels; Rats; Sodium-Potassium-Exchanging ATPase	1997
Dissociation of effects of glutamate receptor antagonists on excitotoxic and hypoxic neuronal cell death in a novel rat cortical culture system. Brain research bulletin, 1997, Volume: 44, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cytological Techniques; Glutamic Acid; Hypoxia; N-Methylaspartate; Neurons; Neurotoxins; Rats; Receptors, Glutamate	1997
Characterization of the anoxia-induced long-term synaptic potentiation in area CA1 of the rat hippocampus. British journal of pharmacology, 1997, Volume: 122, Issue:4 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Chelating Agents; Evoked Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Synapses	1997
Inhibitory effects of hypoxia and adenosine on N-methyl-D-aspartate-induced pial arteriolar dilation in piglets. Brain research, 1998, Jan-12, Volume: 780, Issue:2 Topics: Adenosine; Animals; Animals, Newborn; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Excitatory Amino Acid Agonists; Female; Hypoxia; Immunohistochemistry; Male; N-Methylaspartate; Nitric Oxide; Nitroprusside; Pia Mater; Receptors, N-Methyl-D-Aspartate; Swine; Theophylline; Vasodilator Agents	1998
Eliprodil, a non-competitive, NR2B-selective NMDA antagonist, protects pyramidal neurons in hippocampal slices from hypoxic/ischemic damage. Brain research, 1998, Jan-26, Volume: 782, Issue:1-2 Topics: Animals; Excitatory Amino Acid Antagonists; Hippocampus; Hypoxia; In Vitro Techniques; Ischemia; Male; N-Methylaspartate; Neuroprotective Agents; Piperidines; Pyramidal Cells; Rats; Rats, Sprague-Dawley	1998
The effects of extracellular pH and calcium manipulation on protein synthesis and response to anoxia/aglycemia in the rat hippocampal slice. Brain research, 1998, Jan-26, Volume: 782, Issue:1-2 Topics: Acidosis; Acids; Adenosine Triphosphate; Animals; Calcium; Extracellular Space; Glucose; Hippocampus; Hydrogen; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Male; N-Methylaspartate; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley	1998
Heparin-binding epidermal growth factor-like growth factor mRNA expression in neonatal rat brain with hypoxic/ischemic injury. Brain research, 1999, May-08, Volume: 827, Issue:1-2 Topics: Animals; Animals, Newborn; Blotting, Northern; Brain Chemistry; Brain Ischemia; DNA Probes; Epidermal Growth Factor; Excitatory Amino Acid Agonists; Gene Expression; Heparin-binding EGF-like Growth Factor; Hypoxia; Hypoxia, Brain; In Situ Hybridization; Intercellular Signaling Peptides and Proteins; Microinjections; N-Methylaspartate; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic	1999
Neuroprotective effect of high glucose against NMDA, free radical, and oxygen-glucose deprivation through enhanced mitochondrial potentials. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Oct-15, Volume: 19, Issue:20 Topics: Animals; Cells, Cultured; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Agonists; Glucose; Hypoxia; Mice; Mice, Inbred ICR; Mitochondria; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Reactive Oxygen Species	1999
Free radicals are involved in the damage to protein synthesis after anoxia/aglycemia and NMDA exposure. Brain research, 2000, Feb-28, Volume: 857, Issue:1-2 Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Free Radicals; Hippocampus; Hypoglycemia; Hypoxia; Male; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Vitamin E	2000
Anoxic depolarization mediates acute damage independent of glutamate in neocortical brain slices. Cerebral cortex (New York, N.Y. : 1991), 2001, Volume: 11, Issue:3 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Brain Ischemia; Cortical Spreading Depression; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoxia; Kynurenic Acid; Male; N-Methylaspartate; Neocortex; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glutamate	2001
Interleukin-1beta exacerbates hypoxia-induced neuronal damage, but attenuates toxicity produced by simulated ischaemia and excitotoxicity in rat organotypic hippocampal slice cultures. Neuroscience letters, 2001, Jun-01, Volume: 305, Issue:1 Topics: Animals; Brain Ischemia; Culture Techniques; Dose-Response Relationship, Drug; Glucose; Hippocampus; Hypoxia; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Osmolar Concentration; Rats; Rats, Wistar; Sialoglycoproteins	2001
Intrinsic optical signals in respiratory brain stem regions of mice: neurotransmitters, neuromodulators, and metabolic stress. Journal of neurophysiology, 2001, Volume: 86, Issue:1 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Anti-Bacterial Agents; Antihypertensive Agents; Diazoxide; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glyburide; Hypoglossal Nerve; Hypoglycemic Agents; Hypoxia; Kainic Acid; Macrolides; Mice; Mitochondrial Swelling; N-Methylaspartate; Optics and Photonics; Organ Culture Techniques; Ouabain; Potassium Channels; Respiratory Center; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin	2001
Tissue plasminogen activator is required for striatal post-ischemic synaptic potentiation. Neuroreport, 2002, Jan-21, Volume: 13, Issue:1 Topics: Animals; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hypoxia; In Vitro Techniques; Ischemia; Long-Term Potentiation; Mice; N-Methylaspartate; Neurons; Reference Values; Synapses; Tissue Plasminogen Activator	2002
NMDA receptors, cellular edema, and metabolic stress. Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chickens; Dizocilpine Maleate; Edema; Electron Transport; Glycolysis; Hypoglycemia; Hypoxia; Iodoacetates; Iodoacetic Acid; Ischemia; N-Methylaspartate; Potassium Cyanide; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Retina; Tetrodotoxin	1992
MK-801 protects retinal neurons from hypoxia and the toxicity of glutamate and aspartate. Investigative ophthalmology & visual science, 1992, Volume: 33, Issue:12 Topics: Animals; Culture Techniques; Dextromethorphan; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hypoxia; Kynurenic Acid; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains; Retina	1992
Possible cerebroprotective and in vivo NMDA antagonist activities of sigma agents. Brain research bulletin, 1991, Volume: 26, Issue:3 Topics: Animals; Anticonvulsants; Brain Diseases; Electroshock; Haloperidol; Hypoxia; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nimodipine; Piperidines; Postural Balance; Pyrimidines; Receptors, Opioid; Receptors, sigma; Seizures	1991
Activation of excitatory amino acid receptors cannot alone account for anoxia-induced impairment of protein synthesis in rat hippocampal slices. Journal of neurochemistry, 1991, Volume: 57, Issue:3 Topics: Animals; Aspartic Acid; Carbon Radioisotopes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hippocampus; Hypoxia; Kainic Acid; Lysine; Male; N-Methylaspartate; Nerve Tissue Proteins; Phenazocine; Phencyclidine; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate	1991
Neurotoxicity of quinolinic acid and its derivatives in hypoxic rat hippocampal slices. Brain research, 1991, Dec-24, Volume: 568, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Dose-Response Relationship, Drug; Hippocampus; Hypoxia; In Vitro Techniques; Magnesium; Male; Molecular Structure; N-Methylaspartate; Neurotoxins; Picolinic Acids; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship	1991
Depression of NMDA-evoked acetylcholine release by endogenous adenosine in striatum slices. Advances in experimental medicine and biology, 1991, Volume: 287 Topics: Acetylcholine; Adenosine; Animals; Corpus Striatum; Female; Hypoxia; In Vitro Techniques; N-Methylaspartate; Rats; Rats, Inbred Strains	1991
Cerebral ischemia decreases the behavioral effects and mortality rate elicited by activation of NMDA receptors in mice. Neuropharmacology, 1991, Volume: 30, Issue:11 Topics: Animals; Behavior, Animal; Carbon Dioxide; Dizocilpine Maleate; Female; Hypoxia; Injections, Intraventricular; Ischemic Attack, Transient; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Degeneration; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Survival Rate	1991
Effects of hypoxia-ischemia and MK-801 treatment on the binding of a phencyclidine analogue in the developing rat brain. Stroke, 1990, Volume: 21, Issue:2 Topics: Animals; Animals, Newborn; Aspartic Acid; Autoradiography; Binding Sites; Brain; Brain Ischemia; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hypoxia; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Tritium	1990
Chemically induced hypoglycemia and anoxia: relationship to glutamate receptor-mediated toxicity in retina. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:3 Topics: Adenosine Triphosphate; Amino Acids; Animals; Aspartic Acid; Chick Embryo; Electron Transport; Glycolysis; Hypoglycemia; Hypoxia; Iodoacetates; Iodoacetic Acid; N-Methylaspartate; Phosphocreatine; Receptors, Glutamate; Receptors, Neurotransmitter; Retina	1990
Hippocampal neurons become more vulnerable to glutamate after subcritical hypoxia: an in vitro study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1990, Volume: 10, Issue:6 Topics: Animals; Cell Survival; Cells, Cultured; Glutamates; Hippocampus; Hypoxia; In Vitro Techniques; N-Methylaspartate; Neurons; Rats	1990
Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake. Nature, 1990, Nov-29, Volume: 348, Issue:6300 Topics: Animals; Biological Transport, Active; Brain Diseases; Extracellular Space; Glutamates; Hypoxia; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neuroglia; Neurons; Potassium; Urodela	1990
Anoxia on slow inward currents of immature hippocampal neurons. Journal of neurophysiology, 1989, Volume: 62, Issue:4 Topics: Aging; Animals; Animals, Newborn; Aspartic Acid; Calcium Channels; Electric Conductivity; Hippocampus; Hypoxia; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains	1989
The N-methyl-D-aspartate antagonists aminophosphonovaleric acid and MK-801 reduce anoxic damage to dentate granule and CA1 pyramidal cells in the rat hippocampal slice. Experimental neurology, 1989, Volume: 103, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Evoked Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Male; N-Methylaspartate; Neurotoxins; Pyramidal Tracts; Rats; Rats, Inbred Strains; Valine	1989
Selective sparing of NADPH-diaphorase neurons in neonatal hypoxia-ischemia. Annals of neurology, 1988, Volume: 24, Issue:5 Topics: Animals; Animals, Newborn; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Hypoxia; N-Methylaspartate; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; Neurons; Neuropeptide Y; Rats; Rats, Inbred Strains; Somatostatin	1988