n-methylaspartate has been researched along with Amyotrophic Lateral Sclerosis in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 8 (53.33) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bassi, MS; Buttari, F; Carta, M; Centonze, D; De Rosa, A; Di Maio, A; Errico, F; Gilio, L; Morelli, M; Nuzzo, T; Sasabe, J; Serra, M; Sulzer, D; Usiello, A | 1 |
| Antonini, A; Biocca, S; Caioli, S; Canu, N; Saba, L; Vindigni, G; Zona, C | 1 |
| Fu, R; Heckman, CJ; Jiang, M; Schuster, JE; Siddique, T | 1 |
| Chen, Y; Guillemin, GJ; Meininger, V | 1 |
| Frazzini, V; Longone, P; Marini, C; Nutini, M; Sensi, SL; Spalloni, A | 1 |
| Antoine, JC; Borg, J; Boutahar, N; Camdessanche, JP; Lachuer, J; Lassabliere, F; Reynaud, E; Wierinckx, A | 1 |
| Amendola, J; Durand, J; Roubertoux, P; Verrier, B | 1 |
| Calderó, J; Casas, C; Esquerda, JE; Oppenheim, RW; Tarabal, O | 1 |
| Aiso, S; Chiba, T; Matsuoka, M; Nishimoto, I; Okamoto, K; Sasabe, J; Yamada, M | 1 |
| Akaike, A; Ibi, M; Inoue, R; Kihara, T; Kimura, J; Kitamura, Y; Sawada, H; Shimohama, S; Taniguchi, T; Urushitani, M | 1 |
| Doble, A | 1 |
| Hu, J; Krieger, C; Pelech, SL; Raymond, LA; Wagey, R | 1 |
| Capobianco, A; Comoletti, D; Mennini, T; Muzio, V; Ravizza, T | 1 |
| Drozda, M; Ferrante, RJ; Friedlander, RM; Gullans, S; Hartley, DM; Kim, BY; Kristal, BS; Li, M; Liu, AS; Ona, V; Przedborski, S; Sarang, S; Stavrovskaya, IG; Wu, DC; Zhu, S | 1 |
| Mannen, T | 1 |
2 review(s) available for n-methylaspartate and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
The role of excitotoxicity in neurodegenerative disease: implications for therapy.
Topics: AIDS Dementia Complex; Amyotrophic Lateral Sclerosis; Calcium; Excitatory Amino Acids; Glutamic Acid; Humans; N-Methylaspartate; Neurodegenerative Diseases; Neurotransmitter Agents | 1999 |
[Amyotrophic lateral sclerosis--its problem].
Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Autoimmune Diseases; Cyanobacteria Toxins; Humans; N-Methylaspartate | 1992 |
13 other study(ies) available for n-methylaspartate and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Homeostasis of serine enantiomers is disrupted in the post-mortem caudate putamen and cerebrospinal fluid of living Parkinson's disease patients.
Topics: Alzheimer Disease; Amino Acids; Amyotrophic Lateral Sclerosis; Homeostasis; Humans; N-Methylaspartate; Parkinson Disease; Putamen; Receptors, N-Methyl-D-Aspartate; Serine | 2023 |
Membrane cholesterol depletion in cortical neurons highlights altered NMDA receptor functionality in a mouse model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; beta-Cyclodextrins; Cell Membrane; Cell Survival; Cholesterol; Disease Models, Animal; Electrophysiology; Female; Glutamic Acid; Humans; Male; Membrane Microdomains; Mice; Mice, Transgenic; Motor Neurons; N-Methylaspartate; Proteomics; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Superoxide Dismutase-1 | 2018 |
Progressive changes in synaptic inputs to motoneurons in adult sacral spinal cord of a mouse model of amyotrophic lateral sclerosis.
Topics: Action Potentials; Age Factors; Amyotrophic Lateral Sclerosis; Animals; Biophysics; Chi-Square Distribution; Disease Models, Animal; Disease Progression; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Interneurons; Mice; Mice, Transgenic; Motor Neurons; Mutation; N-Methylaspartate; Patch-Clamp Techniques; Psychomotor Performance; Quinoxalines; Reaction Time; Reflex; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Synapses | 2009 |
Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors.
Topics: Adult; Amyotrophic Lateral Sclerosis; Animals; Brain; D-Aspartic Acid; Functional Laterality; Humans; Japan; Kynurenic Acid; Kynurenine; Motor Neurons; N-Methylaspartate; Quinolinic Acid; Riluzole; Signal Transduction; Tryptophan | 2009 |
Zinc pre-treatment enhances NMDAR-mediated excitotoxicity in cultured cortical neurons from SOD1(G93A) mouse, a model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Culture Techniques; Cell Death; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Humans; Male; Mice; Mice, Transgenic; Motor Neurons; N-Methylaspartate; Neurons; Neurotoxins; Neurotransmitter Agents; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Zinc | 2011 |
Differential effect of oxidative or excitotoxic stress on the transcriptional profile of amyotrophic lateral sclerosis-linked mutant SOD1 cultured neurons.
Topics: Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Gene Expression Profiling; Gene Expression Regulation; Humans; Hydrogen Peroxide; Mice; Mice, Neurologic Mutants; Mice, Transgenic; N-Methylaspartate; Neurons; Neurotoxins; Oligonucleotide Array Sequence Analysis; Oxidants; Oxidative Stress; Statistics, Nonparametric; Superoxide Dismutase; Superoxide Dismutase-1 | 2011 |
Altered sensorimotor development in a transgenic mouse model of amyotrophic lateral sclerosis.
Topics: Action Potentials; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Functional Laterality; Hand Strength; In Vitro Techniques; Mice; Mice, Transgenic; Motor Activity; Motor Neurons; N-Methylaspartate; Psychomotor Performance; Serotonin; Spinal Nerve Roots; Superoxide Dismutase; Superoxide Dismutase-1 | 2004 |
Protein retention in the endoplasmic reticulum, blockade of programmed cell death and autophagy selectively occur in spinal cord motoneurons after glutamate receptor-mediated injury.
Topics: Amyotrophic Lateral Sclerosis; Animals; Anterior Horn Cells; Apoptosis; Autophagy; Axotomy; Chick Embryo; Disease Models, Animal; Endoplasmic Reticulum; Excitatory Amino Acid Agonists; Glutamic Acid; Inclusion Bodies; Microscopy, Electron, Transmission; Models, Neurological; N-Methylaspartate; Nerve Tissue Proteins; Neurofilament Proteins; Neurotoxins; Protein Biosynthesis; Receptors, Glutamate; Stress, Physiological | 2005 |
D-serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Enzyme Activation; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Humans; Mice; Mice, Transgenic; Middle Aged; Motor Neurons; Mutation; N-Methylaspartate; Neuroglia; p38 Mitogen-Activated Protein Kinases; Racemases and Epimerases; Serine; Spinal Cord; Superoxide Dismutase; Up-Regulation | 2007 |
Mechanism of selective motor neuronal death after exposure of spinal cord to glutamate: involvement of glutamate-induced nitric oxide in motor neuron toxicity and nonmotor neuron protection.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Death; Cell Survival; Cells, Cultured; Cyclic GMP; Dicarboxylic Acids; Embryo, Mammalian; Glutamic Acid; Models, Neurological; Motor Neurons; N-Methylaspartate; Neurons; Neurotransmitter Uptake Inhibitors; Nitric Oxide; Nitric Oxide Donors; Pyrrolidines; Rats; Rats, Wistar; Spinal Cord | 1998 |
Modulation of NMDA-mediated excitotoxicity by protein kinase C.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Death; Cell Fractionation; Cell Line; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Humans; Immunoblotting; Indoles; Isoenzymes; Mitogen-Activated Protein Kinases; N-Methylaspartate; Phosphorylation; Protein Isoforms; Protein Kinase C; Protein Structure, Tertiary; Protein Subunits; Pyrroles; Rats; Receptors, N-Methyl-D-Aspartate; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Nitric oxide produced by non-motoneuron cells enhances rat embryonic motoneuron sensitivity to excitotoxins: comparison in mixed neuron/glia or purified cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyotrophic Lateral Sclerosis; Animals; Anterior Horn Cells; Cell Communication; Cell Differentiation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Glycine; Kainic Acid; Magnesium; N-Methylaspartate; Neuroglia; Neurotoxins; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2001 |
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice.
Topics: Age of Onset; Amyotrophic Lateral Sclerosis; Animals; Caspases; Cell Death; Cells, Cultured; Cerebral Cortex; Cytochrome c Group; Disease Progression; Enzyme Activation; Humans; Infarction, Middle Cerebral Artery; Ischemia; Mice; Mice, Inbred C57BL; Minocycline; Mitochondria; Mitochondrial Swelling; N-Methylaspartate; Permeability; Rats; Survival Rate; Tumor Cells, Cultured | 2002 |