n-methylaspartate and Alzheimer Disease

Topics: Alzheimer Disease; Animals; Antioxidants; Biology; Cysteine; Kelch-Like ECH-Associated Protein 1; Mice; N-Methylaspartate; NF-E2-Related Factor 2; Oxidation-Reduction

Topics: Aging; Alzheimer Disease; Brain; Humans; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serine

Topics: Alzheimer Disease; Humans; Memantine; N-Methylaspartate; Neurodegenerative Diseases; Receptors, N-Methyl-D-Aspartate

Topics: Acetylcholine; Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Humans; N-Methylaspartate

Topics: Alzheimer Disease; Amino Acids; Brain; Brain Chemistry; Humans; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Schizophrenia

Topics: Alzheimer Disease; Antidepressive Agents; Antipsychotic Agents; Clinical Trials as Topic; Depression; Drug Repositioning; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Memantine; N-Methylaspartate; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serotonin 5-HT3 Receptor Antagonists

Topics: Alzheimer Disease; Amyloid beta-Peptides; N-Methylaspartate; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antigens, Neoplasm; Apoptosis; Blood-Brain Barrier; Brain-Derived Neurotrophic Factor; Drug Evaluation, Preclinical; Fingolimod Hydrochloride; Humans; Immunologic Factors; Inflammation; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Models, Biological; N-Methylaspartate; Nerve Tissue Proteins; Neuroimmunomodulation; Neuroprotective Agents; Phosphotransferases (Alcohol Group Acceptor); Rats; Signal Transduction; Species Specificity; Sphingolipids; Sphingosine-1-Phosphate Receptors

Topics: Aged; Aging; Alzheimer Disease; Animals; Brain; Cognitive Dysfunction; Disease Models, Animal; Drug Design; Humans; N-Methylaspartate; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

Topics: Alzheimer Disease; Amyloid beta-Peptides; Antibodies, Monoclonal; Brain; Humans; Immunotherapy; N-Methylaspartate; tau Proteins

Topics: Alzheimer Disease; Animals; Brain; Hibernation; Humans; N-Methylaspartate; Neurons; Phosphorylation; Synapses; tau Proteins

Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Humans; N-Methylaspartate

Topics: Alzheimer Disease; Animals; Antioxidants; Flavonoids; Humans; Isoenzymes; Molecular Structure; N-Methylaspartate; NADPH Oxidases; Oxidation-Reduction; Oxidative Stress; Phenols; Phospholipases A2; Plant Extracts; Polyphenols; Receptors, N-Methyl-D-Aspartate; Signal Transduction

Topics: Alzheimer Disease; Cholinesterase Inhibitors; Humans; Memantine; N-Methylaspartate

Topics: Alzheimer Disease; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; N-Methylaspartate; Neuroprotective Agents; Receptors, Glutamate; Synaptic Transmission

Topics: Alzheimer Disease; Antioxidants; Brain; Cardiovascular Agents; Chelating Agents; Cholinesterase Inhibitors; Clinical Trials as Topic; Drug Therapy, Combination; Humans; N-Methylaspartate; Nootropic Agents; Vaccines

Topics: Aging; Alzheimer Disease; Enzyme Inhibitors; Female; Gonadotropin-Releasing Hormone; Gonadotropins; Humans; Luteinizing Hormone; Male; N-Methylaspartate

Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cholinesterase Inhibitors; Disease Progression; Estrogens; Glutamic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; N-Methylaspartate; Neurofibrillary Tangles; Neuropharmacology; Neurotransmitter Agents

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Cathepsin C; Cathepsin G; Cathepsins; DNA, Complementary; Gene Expression; Humans; Membrane Glycoproteins; Membrane Transport Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurofibrillary Tangles; Plaque, Amyloid; Serine Endopeptidases; Serotonin Plasma Membrane Transport Proteins; Synaptic Transmission; Tryptophan Hydroxylase

Topics: Alzheimer Disease; Animals; Brain; Brain Ischemia; Hippocampus; Humans; N-Methylaspartate; Neurons

Topics: Activities of Daily Living; Aged; Alzheimer Disease; Caregivers; Cholinesterase Inhibitors; Disease Progression; Family; Geriatric Assessment; Geriatric Nursing; Humans; Mass Screening; N-Methylaspartate; Neuropsychological Tests; Nurse's Role; Nursing Assessment; Office Visits; Patient Education as Topic; Primary Health Care; Psychiatric Status Rating Scales; Quality of Life; Self Efficacy; Severity of Illness Index; United States

Topics: Activities of Daily Living; Advance Care Planning; Aged; Aged, 80 and over; Alzheimer Disease; Caregivers; Cholinesterase Inhibitors; Dementia; Dementia, Vascular; Humans; Lewy Body Disease; Long-Term Care; Medical History Taking; Middle Aged; N-Methylaspartate; Neurologic Examination; Nutrition Therapy; Physical Examination; Practice Guidelines as Topic; Safety; Social Support

Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Drug Therapy, Combination; Galantamine; Humans; Indans; Memantine; N-Methylaspartate; Nootropic Agents; Phenylcarbamates; Piperidines; Rivastigmine

Topics: Aged; Alzheimer Disease; Amantadine; Antiparkinson Agents; Excitatory Amino Acid Antagonists; Glutamine; Humans; Memantine; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine

Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspartic Acid Endopeptidases; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Endopeptidases; Hippocampus; Humans; Indans; N-Methylaspartate; Nerve Growth Factors; Nicotine; Piperidines; Tacrine

Topics: Adult; Alzheimer Disease; Cognition; Dementia; Double-Blind Method; Down Syndrome; Female; Humans; Male; Memantine; Middle Aged; N-Methylaspartate

Topics: Activities of Daily Living; Aged; Alzheimer Disease; Behavior; Cognition; Disease Progression; Excitatory Amino Acid Antagonists; Female; Humans; Male; Memantine; Middle Aged; N-Methylaspartate; Severity of Illness Index

Topics: Alzheimer Disease; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Drug Liberation; Humans; Male; Memantine; Mice; Mice, Inbred BALB C; Mice, Nude; N-Methylaspartate; Nanoparticles; Nerve Tissue Proteins; Neuroblastoma; Optical Imaging; Oxidative Stress; Particle Size; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Hippocampus; Humans; Integrin beta1; Mice; N-Methylaspartate; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Synapses

Topics: Alzheimer Disease; Computer Simulation; Humans; Information Theory; Memantine; N-Methylaspartate; Neurodegenerative Diseases; Receptors, N-Methyl-D-Aspartate

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Hydrogen Peroxide; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; N-Methylaspartate; Neurodegenerative Diseases; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats

Topics: Alzheimer Disease; Calcium; Calmodulin; Humans; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; N-Methylaspartate; Phosphodiesterase Inhibitors

Topics: ADAM10 Protein; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; HIV Infections; Humans; Membrane Proteins; N-Methylaspartate; Proteasome Inhibitors; Rats; Receptors, N-Methyl-D-Aspartate; Sirtuin 1

Topics: Alzheimer Disease; Animals; Anxiety; Corticosterone; Disease Models, Animal; Female; Male; Mice; Mice, Transgenic; N-Methylaspartate

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Humans; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Phosphorylation; Prion Proteins; Receptors, N-Methyl-D-Aspartate

Topics: Alzheimer Disease; Biological Products; Humans; Ligands; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate

Topics: Alzheimer Disease; Animals; Glycogen Synthase Kinase 3; Hippocampus; Humans; Mechanistic Target of Rapamycin Complex 2; Mice; Mice, Knockout; Mice, Transgenic; N-Methylaspartate; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptors, N-Methyl-D-Aspartate; Signal Transduction

Topics: Alzheimer Disease; Amino Acids; Amyotrophic Lateral Sclerosis; Homeostasis; Humans; N-Methylaspartate; Parkinson Disease; Putamen; Receptors, N-Methyl-D-Aspartate; Serine

Topics: Alzheimer Disease; Disks Large Homolog 4 Protein; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Post-Synaptic Density; Receptors, N-Methyl-D-Aspartate

Topics: Alzheimer Disease; Cell Death; Humans; N-Methylaspartate; Zika Virus; Zika Virus Infection

Topics: Alzheimer Disease; Amyloid beta-Peptides; Cell Death; Hippocampus; Intracellular Signaling Peptides and Proteins; N-Methylaspartate; Neurons

Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Male; Memory; Mice, Transgenic; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate

Topics: Acitretin; ADAM10 Protein; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Adhesion Molecules; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neuronal Outgrowth; Neurons; Proteolysis; Proteome; Rats; RNA Interference; RNA, Small Interfering; Substrate Specificity; Tetraspanins

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disks Large Homolog 4 Protein; Female; Glutamic Acid; Hippocampus; Ionomycin; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Membrane Proteins; N-Methylaspartate; Neuronal Plasticity; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses

Topics: Acrolein; Alzheimer Disease; Animals; Female; Hippocampus; I-kappa B Proteins; Long-Term Potentiation; Male; Memory Disorders; Mice; Mice, Knockout; Microglia; N-Methylaspartate; Neuroprotective Agents; NF-kappa B; Presenilin-1; Presenilin-2; Receptors, N-Methyl-D-Aspartate; Signal Transduction

Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Amyloid beta-Peptides; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Calcium Channels, L-Type; Cells, Cultured; Cognition Disorders; Dentate Gyrus; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Patch-Clamp Techniques; Phosphorylation; Potassium Channels, Voltage-Gated; Synapses; tau Proteins

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Glycogen Synthase Kinase 3; Indoles; Male; Maleimides; Mice; Mice, Transgenic; Molecular Targeted Therapy; N-Methylaspartate; Neuronal Plasticity; Neurons; rab5 GTP-Binding Proteins; Rats; Receptors, N-Methyl-D-Aspartate

Topics: Aging; Alzheimer Disease; Cost of Illness; Excitatory Amino Acid Agonists; Health Behavior; Humans; N-Methylaspartate; Risk Factors

Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Hippocampus; Long-Term Potentiation; Mice, Transgenic; Molecular Targeted Therapy; Mutation; N-Methylaspartate; Neostigmine; Plaque, Amyloid

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Choline O-Acetyltransferase; N-Methylaspartate; Nerve Degeneration; Neurons; Parasympathetic Nervous System; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction

Topics: Aged; Albumins; Aluminum; Alzheimer Disease; Amyloid beta-Peptides; Animals; Atrophy; Blood-Brain Barrier; Brain; Carbohydrate Metabolism; Diabetes Mellitus; Dietary Supplements; Gray Matter; Homocysteine; Humans; Learning; Magnesium; Magnesium Deficiency; Memory; Middle Aged; Models, Theoretical; N-Methylaspartate; Nutritional Sciences; Plasma Exchange; Rats; Silicic Acid; Vitamin B Complex

Topics: Alzheimer Disease; Animals; Cytoskeletal Proteins; Disease Models, Animal; Hippocampus; Male; Membrane Microdomains; Mice; Mice, Transgenic; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Post-Synaptic Density; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses

Topics: Alzheimer Disease; Azepines; Butyrylcholinesterase; Cell Line, Tumor; Cholinesterase Inhibitors; Humans; Indoles; N-Methylaspartate; Neurons; Neuroprotective Agents

Topics: Alzheimer Disease; Animals; Antipsychotic Agents; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Doxycycline; Excitatory Amino Acid Agonists; Exploratory Behavior; Female; Hippocampus; Hyperkinesis; Long-Term Potentiation; Male; Maze Learning; Mice; Mice, Transgenic; Motor Activity; N-Methylaspartate; Peptides; Phosphotransferases; tau Proteins

Topics: Aluminum; Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium Signaling; Disease Models, Animal; Homeostasis; Humans; In Vitro Techniques; Male; Membrane Fluidity; Mice; Mice, Transgenic; Mitochondria; Multiprotein Complexes; N-Methylaspartate; Neurons; Oxygen Consumption; Peptide Fragments; Rats; Rats, Wistar

Topics: Aged; Alzheimer Disease; Anti-Anxiety Agents; Antipsychotic Agents; Databases, Factual; Dopamine Agents; Female; France; Humans; Hypnotics and Sedatives; Male; Memantine; N-Methylaspartate; Psychotropic Drugs; Treatment Outcome

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Calpain; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Glycogen Synthase Kinase 3; Humans; Inhibitory Concentration 50; Male; Memantine; Middle Aged; N-Methylaspartate; Neurons; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Signal Transduction

Topics: alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium; Cholinergic Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Frontal Lobe; Hippocampus; Immunoprecipitation; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Organ Culture Techniques; Peptide Fragments; Phosphorylation; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Synaptosomes

Topics: Activities of Daily Living; Aged; Alzheimer Disease; Caregivers; Cognition; Cost of Illness; Dopamine Agents; Humans; Memantine; N-Methylaspartate

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cadmium Chloride; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Drug Interactions; Electric Stimulation; Endoplasmic Reticulum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Heparin; Humans; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Mutation; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Presenilin-1; Pyramidal Cells; Ryanodine Receptor Calcium Release Channel; tau Proteins; Transglutaminases

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Antipsychotic Agents; Calcium; Cells, Cultured; Cerebral Cortex; Diazoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Gene Expression Regulation; Humans; KATP Channels; Membrane Potential, Mitochondrial; Membrane Potentials; Memory Disorders; Mice; Mice, Transgenic; Mutation; N-Methylaspartate; Oxygen; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Presenilin-1; Rats; RNA, Messenger; tau Proteins; Tauopathies

Topics: Aging; Alzheimer Disease; Animals; Calcium Signaling; Cell Survival; Cells, Cultured; Cerebral Cortex; Electroshock; Energy Metabolism; Environment; Gene Expression; Humans; Interneurons; Lipid Metabolism; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nerve Net; Neuronal Plasticity; Receptor, trkB; Synaptic Transmission

Topics: Alcoholism; Alzheimer Disease; Animals; Antipsychotic Agents; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synapses

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Brain; Cyclin-Dependent Kinase 5; Cysteine; Dendritic Spines; Dynamins; Enzyme Activation; HEK293 Cells; Humans; Mutation; N-Methylaspartate; Nitric Oxide; Nitrosation; Rats; Synapses

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Homeostasis; N-Methylaspartate; Neurons; Peptide Fragments; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

Topics: Alzheimer Disease; Cholinesterase Inhibitors; Galantamine; Humans; Memantine; N-Methylaspartate; Phenylcarbamates; Rivastigmine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium Signaling; Cell Death; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Drug Interactions; Encephalitis; Excitatory Amino Acid Agonists; Fetus; Glutamic Acid; Interleukin-6; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

Topics: Alzheimer Disease; Cholinesterase Inhibitors; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Humans; Memantine; N-Methylaspartate

Topics: Alzheimer Disease; Excitatory Amino Acid Antagonists; Homocysteine; Humans; Hyperhomocysteinemia; Memantine; N-Methylaspartate

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cells, Cultured; Cellular Senescence; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Eye Proteins; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Picrotoxin; Receptors, AMPA; Receptors, GABA; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retina; Taurine

Topics: Afferent Pathways; Aged; Alzheimer Disease; Carbamates; Cerebral Cortex; Cholinergic Fibers; Cholinesterase Inhibitors; Evoked Potentials, Motor; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Motor Cortex; Muscle, Skeletal; N-Methylaspartate; Nerve Net; Neural Inhibition; Phenylcarbamates; Reaction Time; Rivastigmine; Sensory Thresholds; Signal Processing, Computer-Assisted; Transcranial Magnetic Stimulation

Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Animals, Newborn; Calcium; Carnosine; Cell Death; Cell Survival; Cerebellum; Dose-Response Relationship, Drug; Flow Cytometry; Fluorescent Dyes; Free Radicals; Indicators and Reagents; Intracellular Space; Kainic Acid; N-Methylaspartate; Neurons; Propidium; Rats; Reactive Oxygen Species; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Xanthenes

Topics: Adult; Alzheimer Disease; Calcium Channel Blockers; Cholinesterase Inhibitors; Drug Costs; Evidence-Based Medicine; Family Practice; Germany; Ginkgo biloba; Humans; Interviews as Topic; Medicine; Middle Aged; N-Methylaspartate; Nootropic Agents; Phytotherapy; Specialization

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Canada; Cholinesterase Inhibitors; Dementia; Diffusion of Innovation; Dopamine Agents; Drug Approval; Drug Therapy, Combination; Humans; Indans; Memantine; N-Methylaspartate; Nootropic Agents; Randomized Controlled Trials as Topic; Risk Factors

Topics: Age Factors; Alzheimer Disease; Animals; Axotomy; Basal Nucleus of Meynert; Blood Vessels; Cell Death; Choline O-Acetyltransferase; Cholinergic Fibers; Disease Models, Animal; Excitatory Amino Acid Agonists; Immunohistochemistry; Laminin; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A

Topics: Alzheimer Disease; Brain; Calcium; Calcium Channel Blockers; Clinical Trials as Topic; Humans; Ion Channels; Models, Theoretical; N-Methylaspartate

Topics: alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Calcineurin; Cell Membrane; Cerebral Cortex; CREB-Binding Protein; Disease Models, Animal; Electric Conductivity; Endocytosis; Enzyme Activation; Mice; N-Methylaspartate; Neurons; Nuclear Proteins; Peptide Fragments; Protein Transport; Protein Tyrosine Phosphatases; Protein Tyrosine Phosphatases, Non-Receptor; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Signal Transduction; Synapses; Trans-Activators

Topics: Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Brain; Dentate Gyrus; Gene Expression; Hippocampus; Hormone Replacement Therapy; Humans; Membrane Proteins; N-Methylaspartate; Oligonucleotide Array Sequence Analysis; Presenilin-1

Topics: Action Potentials; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Gene Expression; Immunohistochemistry; Male; Mice; Mice, Transgenic; N-Methylaspartate; Neocortex; Patch-Clamp Techniques; Pyramidal Cells; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synapses; Time Factors

Topics: Alzheimer Disease; Animals; Binding Sites; Cell Line; Cysteine; Endoplasmic Reticulum; Humans; Molecular Chaperones; N-Methylaspartate; Neurodegenerative Diseases; Nitric Oxide; Parkinson Disease; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Disulfide-Isomerases; Protein Folding; Receptors, G-Protein-Coupled; Sulfhydryl Compounds; Ubiquitin

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition Disorders; Disease Models, Animal; Entorhinal Cortex; Exploratory Behavior; Gliosis; Male; Maze Learning; Microinjections; N-Methylaspartate; Neurotoxins; Peptide Fragments; Plaque, Amyloid; Rats; Rats, Wistar; Recognition, Psychology; Statistics, Nonparametric

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Arachidonic Acid; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; N-Methylaspartate; NADPH Oxidases; Neurons; Oxidative Stress; Peptide Fragments; Phospholipases A2, Cytosolic; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction

Topics: Acetylcholine; Acetylcholinesterase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Animals; Cells, Cultured; Choline O-Acetyltransferase; Kainic Acid; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Prosencephalon; Receptors, AMPA; Receptors, Kainic Acid

Topics: Adult; Aged; Alzheimer Disease; Animals; Cognition; Cycloserine; Discrimination Learning; Entorhinal Cortex; Female; Glutamic Acid; Humans; Male; Memory; N-Methylaspartate; Rats; Receptors, Glutamate; Temporal Lobe

Topics: Acetylcarnitine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood Physiological Phenomena; Cattle; Cell Death; Cells, Cultured; Cerebral Cortex; Culture Media; Energy Metabolism; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Hippocampus; Humans; Kainic Acid; N-Methylaspartate; Neurons; Peptide Fragments; Rats

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amino Acids; Autoradiography; Binding Sites; Carrier Proteins; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Glutamic Acid; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; N-Methylaspartate; Nerve Tissue Proteins; Parkinson Disease; Receptors, Amino Acid; Receptors, AMPA; Receptors, Glutamate

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; Gas Chromatography-Mass Spectrometry; Humans; Middle Aged; N-Methylaspartate; Parkinson Disease; Rats; Receptors, Glycine; Receptors, Neurotransmitter; Reference Values; Serine; Temporal Lobe

Topics: Alzheimer Disease; Animals; Brain; Cell Survival; Cells, Cultured; Cerebral Cortex; Fetus; Humans; Kinetics; N-Methylaspartate; Neurons; Neurotoxins; Phosphoproteins; Phosphorylation; Rats; tau Proteins; Time Factors

Topics: Alzheimer Disease; Animals; Avoidance Learning; Behavior, Animal; Entorhinal Cortex; Excitatory Amino Acid Agents; Male; Maze Learning; Memory Disorders; N-Methylaspartate; Rats; Rats, Wistar; Stereotaxic Techniques

Topics: Aggression; Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Animals; Brain; Cell Nucleus; Cerebral Amyloid Angiopathy; Humans; Kainic Acid; Lethal Dose 50; Mice; Mice, Inbred Strains; Mice, Transgenic; N-Methylaspartate; Point Mutation

Topics: Alzheimer Disease; Animals; Animals, Newborn; Antibodies; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Apoptosis; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; Humans; Hypoxia-Ischemia, Brain; In Vitro Techniques; Mice; Mice, Inbred CBA; Mice, Knockout; N-Methylaspartate; Neurons; Neurotoxins; Staurosporine

Topics: Alzheimer Disease; Animals; Brain; Cells, Cultured; Disease Models, Animal; Excitatory Amino Acid Agonists; Gene Expression; Humans; Infarction, Middle Cerebral Artery; Kainic Acid; Membrane Proteins; Mice; Mice, Knockout; Mice, Transgenic; N-Methylaspartate; Nerve Degeneration; Neurons; Presenilin-1

Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cerebral Cortex; DNA Damage; Free Radicals; Hippocampus; Humans; N-Methylaspartate; Nerve Degeneration; Nitric Oxide; Peptide Fragments; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar

Topics: Alzheimer Disease; Animals; Antibodies; Apolipoproteins E; Cell Death; Cell Division; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Models, Animal; N-Methylaspartate; Nerve Degeneration; Neuroglia; Neurons; NF-kappa B; Rats; Rats, Sprague-Dawley; RNA, Messenger; Synaptophysin; Time Factors; Up-Regulation

Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Animals; Cells, Cultured; Dithiothreitol; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Hydrogen-Ion Concentration; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neuroprotective Agents; Nootropic Agents; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sesquiterpenes; Spermine; Zinc

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcineurin; Cyclosporine; Dentate Gyrus; Disease Models, Animal; Hippocampus; Immunosuppressive Agents; Long-Term Potentiation; Male; N-Methylaspartate; Phospholipids; Rats; Rats, Sprague-Dawley; Tacrolimus

Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Basal Nucleus of Meynert; Biomarkers; Carbocyanines; Cell Count; Choline O-Acetyltransferase; Cholinergic Fibers; Down-Regulation; Fluorescent Dyes; Immunoglobulin G; Immunohistochemistry; Male; N-Methylaspartate; Neurons; Neurotoxins; Nuclear Proteins; Rats; Rats, Wistar; Receptor, Nerve Growth Factor

Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autoradiography; Cerebral Cortex; Choline O-Acetyltransferase; Electrophoresis, Gel, Two-Dimensional; Humans; Male; Methionine; N-Methylaspartate; Polyribosomes; Protein Biosynthesis; Protein Precursors; Rats; Rats, Inbred Strains; Substantia Innominata; Sulfur Radioisotopes

Topics: 2-Amino-5-phosphonovalerate; Alzheimer Disease; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glycine; Kainic Acid; N-Methylaspartate; Phosphoserine; Rats; Receptors, Glutamate; Receptors, Neurotransmitter

Topics: Alzheimer Disease; Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cholinergic Fibers; Female; Hippocampus; Male; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Rats; Septal Nuclei

Topics: Alzheimer Disease; Aspartic Acid; Binding Sites; Frontal Lobe; Glutamates; Glutamic Acid; Humans; Membranes; N-Methylaspartate; Phencyclidine; Reference Values

Topics: Aged; Aged, 80 and over; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Autoradiography; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Radioligand Assay; Receptors, AMPA; Receptors, Neurotransmitter

Topics: Aging; Alzheimer Disease; Animals; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Inbred F344; Time Factors

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Glutamates; Kainic Acid; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neurotoxins

Topics: Aged; Alzheimer Disease; Aspartic Acid; Autoradiography; Female; Glutamates; Glutamic Acid; Hippocampus; Humans; Kainic Acid; Male; Middle Aged; N-Methylaspartate; Neuronal Plasticity; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission

Topics: Alzheimer Disease; Aspartic Acid; Autoradiography; Flunitrazepam; Glutamates; Glutamic Acid; Hippocampus; Histocytochemistry; Humans; Muscimol; N-Methylaspartate; Receptors, GABA-A; Receptors, Muscarinic; Tissue Distribution

Topics: Alzheimer Disease; Animals; Aspartic Acid; Autoradiography; Brain; Brain Mapping; Calcium; Glutamates; Humans; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship