n-methylaspartate and Allodynia

Topics: Analgesics; Analgesics, Opioid; Animals; Benzamides; Dizocilpine Maleate; Drug Tolerance; Hot Temperature; Humans; Hyperalgesia; Morphine; Multiple Chemical Sensitivity; N-Methylaspartate; Narcotics; Nerve Degeneration; Nerve Tissue Proteins; Neuralgia; Neuronal Plasticity; Nitric Oxide; Phosphorylation; Poly(ADP-ribose) Polymerases; Posterior Horn Cells; Protein Kinase C; Protein Processing, Post-Translational; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Opioid, mu; Sciatic Nerve; Spinal Cord

Topics: Animals; Connexins; Hyperalgesia; N-Methylaspartate; Nerve Tissue Proteins; Nociception; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P2X7; Spinal Cord

Topics: Animals; Apoptosis; Caspase 3; Down-Regulation; Glutamates; Hyperalgesia; Interleukin-6; N-Methylaspartate; Neuralgia; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord Injuries; Tumor Necrosis Factors

Topics: Animals; Antidepressive Agents; Comorbidity; Depression; Hyperalgesia; Male; N-Methylaspartate; Neuralgia; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spiders

Topics: Animals; Berberine; HEK293 Cells; Humans; Hyperalgesia; Mice; Molecular Docking Simulation; Morphine; N-Methylaspartate; Nitric Oxide

Topics: Animals; Excitatory Amino Acid Antagonists; Glutamates; HMGB1 Protein; Humans; Hyperalgesia; Injections, Spinal; Male; Mice; Microglia; N-Methylaspartate; Peripheral Nerves; Receptors, N-Methyl-D-Aspartate; Spinal Cord Dorsal Horn

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Flavonoids; Hyperalgesia; Imidazoles; MAP Kinase Signaling System; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nerve Tissue Proteins; Nociception; Pain; Pain Measurement; Protein Kinase Inhibitors; Pyridines; Spinal Cord

Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Hyperalgesia; Iontophoresis; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Resveratrol; Sensory Receptor Cells; Stilbenes; Trigeminal Nucleus, Spinal

Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; California; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Haloperidol; Hospice Care; Humans; Hyperalgesia; Male; Medical Audit; Methadone; Middle Aged; N-Methylaspartate; Pain Management; Retrospective Studies

Topics: Animals; Cytosol; Glutamic Acid; Glutamine; Hot Temperature; Hyperalgesia; Immunoprecipitation; Lumbar Vertebrae; Male; N-Methylaspartate; Nitrogen; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptosomes; Tyrosine

Topics: Acute Pain; Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Hyperalgesia; Injections, Intraperitoneal; Male; N-Methylaspartate; Naloxone; Narcotic Antagonists; Pain, Postoperative; Panax; Rats; Rats, Sprague-Dawley; Saponins

Topics: Animals; Calcineurin Inhibitors; Casein Kinase II; Dichlororibofuranosylbenzimidazole; Excitatory Postsynaptic Potentials; Hyperalgesia; Male; Miniature Postsynaptic Potentials; N-Methylaspartate; Physical Stimulation; Posterior Horn Cells; Rats, Sprague-Dawley; Spinal Cord; Tacrolimus; Touch; Triazoles

Topics: Analgesics; Animals; Hyperalgesia; Injections, Intramuscular; Male; Muscle, Skeletal; N-Methylaspartate; Pain Threshold; Panax; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Saponins; Sodium Chloride

Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hyperalgesia; Malondialdehyde; N-Methylaspartate; Nitric Oxide; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Remifentanil; Streptozocin

Topics: Anesthetics, Local; Animals; Constriction, Pathologic; Hyperalgesia; Lidocaine; Male; Methysergide; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neural Pathways; Neuralgia; Neurons; Pain Measurement; Physical Stimulation; Pretectal Region; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Sciatic Neuropathy

Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Freund's Adjuvant; Hyperalgesia; Male; Myalgia; Myositis; N-Methylaspartate; Oximes; Pain Threshold; Rats; Rats, Sprague-Dawley; Trigeminal Ganglion; TRPA1 Cation Channel; TRPC Cation Channels; Up-Regulation

Topics: Analgesics; Animals; Botulinum Toxins, Type A; Carrageenan; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nociception; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fos; Receptors, AMPA; Spinal Cord Dorsal Horn; Substance P

Topics: Analgesics, Opioid; Animals; beta-Arrestin 2; Chronic Pain; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Humans; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Mice, Knockout; N-Methylaspartate; Neuralgia; Neurons; Peripheral Nerve Injuries; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Spinal Cord Dorsal Horn; Substantia Gelatinosa; Time Factors

Topics: Animals; D-Amino-Acid Oxidase; Disease Models, Animal; Enzyme Inhibitors; Ethylenediamines; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Morpholines; N-Methylaspartate; Nerve Tissue Proteins; Neuralgia; Phosphorylation; Physical Stimulation; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Serine; Sigma-1 Receptor; Spinal Cord

Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Brimonidine Tartrate; Calcium; Clonidine; Dinoprostone; Drug Interactions; Excitatory Amino Acid Agonists; Exploratory Behavior; Hyperalgesia; Injections, Spinal; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Pain Measurement; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; N-Methylaspartate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substance P

Topics: Acetanilides; Analysis of Variance; Animals; Ankyrins; Calcium Channels; Capsaicin; Cholecystokinin; Cinnamomum zeylanicum; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Hyperalgesia; Male; N-Methylaspartate; Pain Measurement; Peripheral Nervous System Diseases; Purines; Rats; Rats, Wistar; Sleep Deprivation; Spinal Cord; TRPA1 Cation Channel; TRPC Cation Channels

Topics: Animals; Cognition Disorders; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Exploratory Behavior; Fluoroacetates; Glycine; Herb-Drug Interactions; Hippocampus; Hyperalgesia; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Neurons; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Recognition, Psychology; Sarcosine; Sciatic Neuropathy

Topics: Analysis of Variance; Animals; Behavior, Animal; Dizocilpine Maleate; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hyperalgesia; In Vitro Techniques; Leptin; Male; Membrane Potentials; Mice; Mice, Knockout; N-Methylaspartate; Neuralgia; Pain Measurement; Patch-Clamp Techniques; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Receptors, N-Methyl-D-Aspartate; Sensory Receptor Cells; Signal Transduction; Spinal Cord; STAT3 Transcription Factor; Up-Regulation

Topics: Animals; Excitatory Amino Acid Antagonists; Hyperalgesia; Male; Mice; N-Methylaspartate; Pain Measurement; Phosphorylation; Piperidines; Posterior Horn Cells; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spinal Cord; Synapses

Topics: Animals; Calcium; Calcium Signaling; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Electrophysiological Phenomena; Extracellular Signal-Regulated MAP Kinases; Hyperalgesia; Immunohistochemistry; Injections, Spinal; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mitochondria; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Nuclear Proteins; Pain; Patch-Clamp Techniques; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Superoxides; Synapses

Topics: Age Factors; Animals; Disease Models, Animal; Hyperalgesia; Male; N-Methylaspartate; Neuralgia; Nociception; Pain Threshold; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley

Topics: Animals; Carrageenan; Cell Count; Disease Models, Animal; Electrophysiological Phenomena; Female; Formaldehyde; Gene Deletion; Gene Expression Regulation; Gene Knockout Techniques; Hyperalgesia; Inflammation; Locomotion; Male; Mice; N-Methylaspartate; Neuralgia; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Receptor, EphB1; Sciatic Nerve; Signal Transduction

Topics: Animals; Freund's Adjuvant; Hyperalgesia; Inflammation; Injections, Spinal; Male; N-Methylaspartate; Organometallic Compounds; Pain Threshold; Phenanthrolines; Phosphorylation; Posterior Horn Cells; Protein Tyrosine Phosphatases; Rats; Receptors, N-Methyl-D-Aspartate; src-Family Kinases; Vanadates

Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Hyperalgesia; Immunohistochemistry; Injections, Intraperitoneal; Injections, Intravenous; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tooth Injuries; Touch; Trigeminal Nuclei

Topics: Acetic Acid; Amino Acid Chloromethyl Ketones; Animals; Behavior, Animal; Capillary Permeability; Endothelins; Evans Blue; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hyperalgesia; Indazoles; Injections, Intraperitoneal; Male; Mice; N-Methylaspartate; Nociceptors; Oligopeptides; Pain Measurement; Peptide Fragments; Peptides, Cyclic; Physical Stimulation; Piperidines; Reaction Time; Receptor, Endothelin A; Receptor, Endothelin B; Thrombin; Urea

Topics: Animals; Carrageenan; Dizocilpine Maleate; Hot Temperature; Hyperalgesia; Inflammation; Injections, Spinal; Kaolin; Male; N-Methylaspartate; Pain; Pain Measurement; Phenols; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord

Topics: Animals; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Astrocytes; Avian Proteins; Basigin; Blood Proteins; Dialysis; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Hyperalgesia; Immunohistochemistry; Male; Membrane Glycoproteins; Microglia; Mitogen-Activated Protein Kinases; N-Methylaspartate; p38 Mitogen-Activated Protein Kinases; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors

Topics: Animals; Binding Sites; Dependovirus; Excitatory Postsynaptic Potentials; Female; Formaldehyde; Genetic Vectors; Hyperalgesia; In Vitro Techniques; Integrases; Introns; Lumbosacral Region; Male; Mice; Mice, Mutant Strains; Motor Activity; N-Methylaspartate; Pain; Pain Measurement; Patch-Clamp Techniques; Posterior Horn Cells; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Transduction, Genetic; Viral Proteins

Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Drug Antagonism; Dynorphins; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Hyperalgesia; Injections, Spinal; Isoenzymes; Membrane Proteins; Microdialysis; N-Methylaspartate; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Rats; Spinal Cord

Topics: Animals; Blotting, Western; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Hindlimb; Hyperalgesia; Immunohistochemistry; Injections, Spinal; Isoenzymes; Lumbosacral Region; Male; N-Methylaspartate; Neuroglia; Neurons; Physical Stimulation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Up-Regulation

Topics: Animals; Excitatory Amino Acid Agonists; Hyperalgesia; Male; Manganese; N-Methylaspartate; Nitrogen; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Superoxide Dismutase; Superoxides

Topics: Animals; Brain-Derived Neurotrophic Factor; Capsaicin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hyperalgesia; Male; N-Methylaspartate; Nerve Fibers, Unmyelinated; Organ Culture Techniques; Pain Measurement; Phosphorylation; Posterior Horn Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; src-Family Kinases; Stimulation, Chemical; Substance P

Topics: Analgesics, Opioid; Animals; Autoradiography; Behavior, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; Glycine; Hyperalgesia; Indoles; Injections, Spinal; Morphine; N-Methylaspartate; Narcotics; Oligonucleotides, Antisense; Pain; Pain Measurement; Rats; Reaction Time; Receptors, N-Methyl-D-Aspartate; RNA Probes; RNA, Messenger; Spinal Cord

Topics: Animals; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Group IV Phospholipases A2; Hyperalgesia; Male; N-Methylaspartate; Pain Measurement; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Spinal Cord

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Hyperalgesia; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Nerve Tissue Proteins; Pain Measurement; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bradykinin; Drug Synergism; Glutamic Acid; Hyperalgesia; In Vitro Techniques; Mice; Mice, Knockout; N-Methylaspartate; Pain; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Spinal Cord; Synaptic Transmission

Topics: Amygdala; Anesthetics, Inhalation; Animals; Avoidance Learning; Desflurane; Excitatory Amino Acid Agonists; Halothane; Hyperalgesia; Isoflurane; Male; Memory; Methyl Ethers; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Sevoflurane

Topics: Amygdala; Anesthetics, Inhalation; Animals; Avoidance Learning; Desflurane; Excitatory Amino Acid Agonists; Halothane; Hyperalgesia; Isoflurane; Male; Memory; Methyl Ethers; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Sevoflurane

Topics: Anesthetics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cyclooxygenase 1; Cyclooxygenase 2; Diclofenac; Eugenol; Excitatory Amino Acid Agonists; Formaldehyde; GABA Agonists; Hyperalgesia; Male; Mice; Muscimol; N-Methylaspartate; Nociceptors

Topics: Analgesics, Opioid; Analysis of Variance; Animals; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Inflammation; Injections, Intraventricular; Injections, Subcutaneous; Male; N-Methylaspartate; Pain; Pain Measurement; Rats; Rats, Inbred F344; Receptors, Opioid; Sex Factors

Topics: Analgesics; Animals; Behavior, Animal; Cycloserine; Dose-Response Relationship, Drug; Hyperalgesia; Limbic System; N-Methylaspartate; Neuralgia; Pain Measurement; Rats; Rats, Sprague-Dawley; Treatment Outcome

Topics: Adrenergic alpha-Antagonists; Amines; Amitriptyline; Analgesics; Animals; Clonidine; Cyclohexanecarboxylic Acids; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Memantine; Mice; Mice, Inbred C57BL; Morphine; N-Methylaspartate; Pain; Peripheral Nervous System; Phenylephrine; Piperazines; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, N-Methyl-D-Aspartate; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Reproducibility of Results; Spinal Cord; Spinal Nerves; Time Factors

Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hyperalgesia; Immunohistochemistry; Inflammation; Kainic Acid; Mice; Mononeuropathies; N-Methylaspartate; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nociceptors; Pain; Spinal Cord; Time Factors

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Benzene Derivatives; Bradykinin; Dinoprostone; Freund's Adjuvant; Glutamic Acid; Hyperalgesia; Inflammation Mediators; Male; Mice; N-Methylaspartate; Neuralgia; Neurogenic Inflammation; Nociceptors; Organoselenium Compounds; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Sciatic Neuropathy

Topics: Action Potentials; Animals; Disease Models, Animal; Efferent Pathways; Excitatory Amino Acid Antagonists; Functional Laterality; Hyperalgesia; Ligation; Male; Medulla Oblongata; N-Methylaspartate; Neural Inhibition; Neuralgia; Neurons, Afferent; Nociceptors; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Reticular Formation; Sciatic Neuropathy; Spinothalamic Tracts

Topics: Acute Disease; Analgesics, Opioid; Animals; Capsaicin; Data Interpretation, Statistical; Dextromethorphan; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Hot Temperature; Hyperalgesia; Male; Morphine; N-Methylaspartate; Pain Measurement; Rats; Rats, Inbred F344; Sex Characteristics

Topics: Acetaminophen; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Behavior, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Spinal; N-Methylaspartate; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Cord Diseases; Substance P

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arginine; Calcium; Cycloleucine; Disease Models, Animal; Excitatory Amino Acids; Hot Temperature; Hyperalgesia; Male; N-Methylaspartate; Neuronal Plasticity; Neurons, Afferent; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stress, Mechanical

Topics: Adrenal Medulla; Animals; Dose-Response Relationship, Drug; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; N-Methylaspartate; Naloxone; Nociceptors; Pain; Phentolamine; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord

Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Electric Stimulation; Hyperalgesia; In Vitro Techniques; N-Methylaspartate; Nerve Fibers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Reflex; Spinal Cord; Spinal Nerve Roots

Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Cordotomy; Formaldehyde; Hot Temperature; Hyperalgesia; Injections, Spinal; Injections, Subcutaneous; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord

Topics: Animals; Chronic Disease; Dizocilpine Maleate; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; N-Methylaspartate; Nervous System Diseases; Nociceptors; Physical Stimulation; Rats; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve

Topics: Animals; Biotransformation; Enzyme Activation; Excitatory Amino Acid Agonists; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; N-Methylaspartate; Nitric Oxide; Pain Measurement; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Capsaicin; Electric Stimulation; Endocytosis; Evoked Potentials; Ganglia, Spinal; Hyperalgesia; Long-Term Potentiation; Male; Microscopy, Confocal; Microscopy, Fluorescence; Models, Neurological; N-Methylaspartate; Neurokinin-1 Receptor Antagonists; Quinuclidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P

Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Glutamate; Serine; Stereoisomerism; Substance P

Topics: Afferent Pathways; Amygdala; Animals; Behavior, Animal; Disinfectants; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Fear; Formaldehyde; GABA Agonists; Hindlimb; Hyperalgesia; Locomotion; Male; Morphine; Muscimol; N-Methylaspartate; Narcotics; Nociceptors; Pain; Rats; Rats, Sprague-Dawley

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Hyperalgesia; Indomethacin; Injections, Spinal; Isoenzymes; Male; N-Methylaspartate; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides

Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; N-Methylaspartate; Pain Measurement; Physical Stimulation; Proteins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord

Topics: Acute Disease; Animals; Dithionitrobenzoic Acid; Dithiothreitol; Dynorphins; Excitatory Amino Acid Agonists; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Oxidation-Reduction; Pain; Pain Measurement; Receptors, N-Methyl-D-Aspartate; Reducing Agents; Signal Transduction; Spinal Cord; Sulfhydryl Reagents; Synaptic Transmission

Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dizocilpine Maleate; Enzyme Inhibitors; Furans; Hyperalgesia; Injections, Spinal; Isoenzymes; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Sheep; Spinal Cord

Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Agonists; Hyperalgesia; Injections, Spinal; Male; Methadone; Mice; Morphine; N-Methylaspartate; Pain Measurement; Rats; Rats, Sprague-Dawley; Stereoisomerism

Topics: Animals; Animals, Newborn; Behavior, Animal; Brain-Derived Neurotrophic Factor; Carrageenan; Excipients; Excitatory Amino Acid Agonists; Hyperalgesia; Immunoglobulin G; Injections, Spinal; Male; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Neurons, Afferent; Nociceptors; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptors, Nerve Growth Factor; Reflex; Spinal Cord

Topics: Animals; Antibodies; Behavior, Animal; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; Guanylate Cyclase; Hyperalgesia; Male; Myelitis; N-Methylaspartate; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nociceptors; Pain; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Thionucleotides

Topics: Animals; Behavior, Animal; Blotting, Western; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Formaldehyde; Hyperalgesia; Immunohistochemistry; Injections, Spinal; Male; N-Methylaspartate; Oligonucleotides, Antisense; Pain; Pain Measurement; PC12 Cells; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord

Topics: Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Hyperalgesia; Injections, Spinal; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Thionucleotides

Topics: Animals; Dinoprostone; Dizocilpine Maleate; Excitatory Amino Acids; Formaldehyde; Hyperalgesia; Indomethacin; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Time Factors

Topics: Animals; Estrus; Excitatory Amino Acid Agonists; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Lactation; N-Methylaspartate; Ovariectomy; Pregnancy; Progesterone; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord

Topics: Analgesics, Opioid; Animals; Behavior, Animal; Blotting, Western; Cold Temperature; Dose-Response Relationship, Drug; Hot Temperature; Hyperalgesia; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Knockout; Morphine; N-Methylaspartate; Oligonucleotides, Antisense; Pain; Pain Measurement; Phorbol 12,13-Dibutyrate; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Sciatic Nerve; Touch

Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hot Temperature; Hyperalgesia; Injections, Spinal; Isoquinolines; Male; N-Methylaspartate; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord

Topics: Animals; Apoptosis; Causalgia; Constriction; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Hot Temperature; Hyperalgesia; In Situ Nick-End Labeling; Male; Models, Neurological; N-Methylaspartate; Paralysis; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Reaction Time; Sciatic Nerve

Topics: Action Potentials; Animals; Behavior, Animal; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hyperalgesia; Isoenzymes; Mice; Mice, Knockout; Mustard Plant; N-Methylaspartate; Neuralgia; Pain Measurement; Physical Stimulation; Plant Extracts; Plant Oils; Posterior Horn Cells; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Spinal Cord

Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Ibuprofen; Injections, Intraperitoneal; Injections, Spinal; Isoenzymes; Male; Membrane Proteins; N-Methylaspartate; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

Topics: Analgesics, Opioid; Animals; Central Nervous System Diseases; Dinoprostone; Excitatory Amino Acid Agonists; Functional Laterality; Hot Temperature; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Mice; Morphine; N-Methylaspartate; Pain Measurement; Peripheral Nervous System Diseases; Reaction Time

Topics: Animals; Drug Synergism; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; N-Methylaspartate; Nociceptors; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Serine; Substance P

Topics: Animals; Excitatory Amino Acid Agonists; Glycine Agents; Hyperalgesia; Male; N-Methylaspartate; Neurons, Afferent; Pain; Peripheral Nervous System Diseases; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Sensation Disorders; Strychnine

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Cycloleucine; Hemoglobins; Hydroxylamine; Hydroxylamines; Hyperalgesia; Ibotenic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Spinal Cord; Time Factors

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hyperalgesia; Ibotenic Acid; Injections, Spinal; N-Methylaspartate; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P