Page last updated: 2024-08-26

n-methyladenosine and Lung Neoplasms

n-methyladenosine has been researched along with Lung Neoplasms in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (11.11)24.3611
2020's40 (88.89)2.80

Authors

AuthorsStudies
Li, Q; Wang, C; Xiong, Y; Yang, X; Zhang, D; Zhang, R1
Guo, M; Li, Z; Ming, L; Qin, Z; Wan, J; Wang, Y; Yang, Z; Zhao, Z; Zheng, J1
Gao, S; He, J; Luo, Y; Sun, N; Tan, F; Wang, L; Wu, P; Xue, L; Xue, Q; Yang, Z; Zeng, H; Zeng, Q; Zhang, C; Zhang, G; Zhang, Z; Zheng, B1
Chen, YM; Chien, CS; Chien, Y; Chiou, SH; Hsiao, YJ; Hsu, PK; Liang, Y; Lin, TW; Lin, TY; Luo, YH; Teng, PC; Teng, YC; Wang, ML; Yang, YP; Yarmishyn, AA1
Bai, Z; Wu, X1
He, J; Luo, Y; Sun, N; Wang, L; Wu, P; Xue, Q; Yang, Z; Zeng, Q; Zhang, C; Zhang, G; Zhang, Y; Zhang, Z1
Bao, F; Chu, X; Feng, L; Sun, Z; Wang, W1
Dong, Z; Feng, W; Gao, M; Han, J; Huang, H; Huang, J; Kloeber, JA; Liu, S; Lou, Z; Qi, Z; Xu, M; Xu, Z1
Chen, B; Hu, Z; Zhang, Y; Zhu, L1
Ding, H; Gao, C; Kong, N; Li, J; Sun, Z; Tang, T; Wu, L; Xu, M; Zhang, F1
Huang, T; Ye, W1
Cui, Z; Guo, B; Jia, E; Ren, N; Xue, J; Zhang, B1
Dong, C; Fu, Z; Li, D; Song, Y1
Bai, L; Chen, Q; Hu, CP; Jiang, J; Li, YY; Wan, RJ; Zhang, Y; Zhao, BR1
Fan, J; Geng, W; Huang, Q; Jin, Y; Li, Y; Tan, Q; Xiao, W; Xu, J; Yang, G; Yin, Z1
Huang, Y; Ma, M; Wang, B; Wang, W; Yang, Y; Ye, L; Zhao, G1
Chen, Y; Liao, X; Ling, Q; Liu, C; Wu, S1
Cai, F; Fu, Y; Gai, Y; Ge, X; Qin, X; Shang, Y; Xiao, H; Xu, J; Zhou, C1
Chen, H; Hu, B; Lyu, Y; Qian, D; Shao, G; Yan, Q; Zhu, L1
Ge, H; Jin, L; Wang, N; Wang, X; Wang, Y; Wu, S; Xu, Y; Zhao, J; Zhou, F1
Bian, J; Bubenik, JL; Fernandez, P; Hiers, NM; Li, L; Li, T; Sheng, P; Swanson, MS; Traugot, CM; Wang, Y; Xie, M1
Jiang, W; Liu, H; Ma, X; Meng, Q; Wang, S; Xu, C; Zhou, S; Zhou, X1
Chao, Y; Ji, W; Shang, J1
Chen, L; Chen, Z; Deng, Q; Dinglin, X; Hou, X; Huang, H; Li, D; Ling, Y; Lv, Z; Ma, S; Peng, Y; Wang, H; Wu, Y1
Chen, J; Chen, Y; Lin, L; Xu, F; Zhang, H1
Chen, P; Ma, L; Qian, Q; Zhao, X; Zhu, Z1
Chen, F; Chen, Z; Li, J; Lin, X; Lv, Z; Peng, Y; Wang, H1
Hu, Q; Li, J; Liu, L; Liu, X; Sun, R; Zhang, Y1
Chen, JZ; Chen, WW; Hang, Y; Qi, JW; Wang, HH; Wang, J; Wu, JX; Zhou, XX1
Xie, Y; Zhao, W1
Feng, F; Gao, C; Li, H; Liu, C; Liu, L; Sun, C; Zhou, C; Zhuang, J1
Bu, P; Feng, Y; Guo, Y; Hu, X; Jiang, A; Li, D; Lin, Y; Liu, C; Liu, Y; Wang, X; Yan, H; Zhang, L; Zhang, S1
Ding, X; Li, D; Peng, Y; Wang, X; Wang, Y; Wu, Y; Yang, A; Yang, P; Yin, H; Yu, Y; Zhang, J; Zhang, R; Zhang, X1
Chang, N; Che, Y; Jiang, J; Qiao, T; Wu, B; Wu, Y; Xiong, J; Xu, L; Zhang, J; Zhang, X; Zhang, Y; Zhou, Y1
Cang, S; Jia, G; Ma, P; Song, Z1
Cheng, Y; Dong, H; Wang, M; Wang, S; Xu, H; Zhou, J1
Ning, J; Okon, I; Satyanarayana, G; Song, P; Xu, S; Zhang, D; Zheng, X; Zou, MH1
Chen, E; Dong, L; Jiang, C; Li, J; Li, X; Liu, P; Lu, B; Lu, Y; Qian, X; Qiu, Q; Yang, J; Ying, K1
He, X; Hu, K; Jin, M; Li, G; Liu, W; Song, Y; Wu, X; Xiong, M; Zeng, Z; Zhang, Q; Zhao, D; Zhu, J1
Chen, L; Lv, X; Ou-Yang, H; Ti, X; Wu, S; Xu, X; Zhang, Y; Zhao, F1
Huang, Z; Shi, J; Shi, M; Wang, J; Zhang, H; Zheng, M; Zhou, H; Zhou, Y1
Dai, H; Gu, S; Sun, D; Zhang, Z1
Du, Z; Jin, Y; Liu, J; Ren, D; Wang, H; Zhang, H1
Bley, N; Chen, J; Dahl, A; Fuchs, T; Glaß, M; Haase, J; Huang, H; Hüttelmaier, S; Lederer, M; Müller, S; Posern, G; Singh, AK1
Gao, Y; Han, Y; Jia, W; Li, B; Li, J; Qian, Z; Zhang, H; Zheng, H1

Reviews

2 review(s) available for n-methyladenosine and Lung Neoplasms

ArticleYear
RNA Modifications and Epigenetics in Modulation of Lung Cancer and Pulmonary Diseases.
    International journal of molecular sciences, 2021, Sep-30, Volume: 22, Issue:19

    Topics: Adenosine; Animals; Epigenesis, Genetic; Humans; Lung Diseases; Lung Neoplasms; RNA; RNA Processing, Post-Transcriptional; RNA, Long Noncoding; RNA, Messenger

2021
The Important Role of N6-methyladenosine RNA Modification in Non-Small Cell Lung Cancer.
    Genes, 2021, 03-19, Volume: 12, Issue:3

    Topics: Adenosine; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Disease Progression; Drug Resistance, Neoplasm; Epigenesis, Genetic; Humans; Lung Neoplasms; Prognosis; RNA

2021

Trials

1 trial(s) available for n-methyladenosine and Lung Neoplasms

ArticleYear
Risk stratification of lung adenocarcinoma using a nomogram combined with ferroptosis-related LncRNAs and subgroup analysis with immune and N6-methyladenosine modification.
    BMC medical genomics, 2022, 01-29, Volume: 15, Issue:1

    Topics: Adenocarcinoma of Lung; Adenosine; Ferroptosis; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Nomograms; Risk Assessment; RNA, Long Noncoding

2022

Other Studies

42 other study(ies) available for n-methyladenosine and Lung Neoplasms

ArticleYear
Gene and prognostic value of N6-methyladenosine (m6A) modification regulatory factors in lung adenocarcinoma.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2022, 07-01, Volume: 31, Issue:4

    Topics: Adenocarcinoma of Lung; Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Humans; Lung Neoplasms; Methyltransferases; Prognosis

2022
N-6 methylation-related lncRNA is potential signature in lung adenocarcinoma and influences tumor microenvironment.
    Journal of clinical laboratory analysis, 2021, Volume: 35, Issue:11

    Topics: Adenocarcinoma of Lung; Adenosine; Aged; Computational Biology; DNA Methylation; Female; Humans; Lung Neoplasms; Male; Middle Aged; RNA, Long Noncoding; Transcriptome; Tumor Microenvironment

2021
The landscape of m
    Molecular cancer, 2021, 09-27, Volume: 20, Issue:1

    Topics: Adenosine; Biomarkers, Tumor; Computational Biology; Disease Susceptibility; Gene Expression Regulation, Neoplastic; Genetic Variation; Humans; Lung Neoplasms; Methylation; Prognosis; RNA; Signal Transduction; Small Cell Lung Carcinoma

2021
Multi-omics analysis of m
    Scientific reports, 2021, 10-22, Volume: 11, Issue:1

    Topics: Adenocarcinoma of Lung; Adenosine; Aged; Biomarkers, Tumor; CTLA-4 Antigen; Female; Gene Expression Regulation, Neoplastic; Humans; Immunotherapy; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Male; Prognosis; Tumor Microenvironment

2021
m
    Journal of hematology & oncology, 2021, 11-10, Volume: 14, Issue:1

    Topics: Adenosine; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Small Cell Lung Carcinoma

2021
An N
    Mathematical biosciences and engineering : MBE, 2022, Volume: 19, Issue:1

    Topics: Adenocarcinoma of Lung; Adenosine; Biomarkers, Tumor; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms

2022
m6A demethylation of cytidine deaminase APOBEC3B mRNA orchestrates arsenic-induced mutagenesis.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:2

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Arsenic; Carcinoma, Non-Small-Cell Lung; Cytidine Deaminase; Demethylation; Humans; Lung Neoplasms; Minor Histocompatibility Antigens; Mutagenesis; RNA, Messenger

2022
N6-methyladenosine-induced SVIL antisense RNA 1 restrains lung adenocarcinoma cell proliferation by destabilizing E2F1.
    Bioengineered, 2022, Volume: 13, Issue:2

    Topics: A549 Cells; Adenocarcinoma of Lung; Adenosine; Cell Proliferation; E2F1 Transcription Factor; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Membrane Proteins; Methyltransferases; Microfilament Proteins; RNA Stability; RNA, Antisense; RNA, Long Noncoding; Tumor Cells, Cultured

2022
Correlation analysis of m6A-modified regulators with immune microenvironment infiltrating cells in lung adenocarcinoma.
    PloS one, 2022, Volume: 17, Issue:2

    Topics: Adenocarcinoma of Lung; Adenosine; Humans; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Methylation; RNA; RNA Processing, Post-Transcriptional; Tumor Microenvironment

2022
Construction and validation of a novel prognostic model for lung squamous cell cancer based on N6-methyladenosine-related genes.
    World journal of surgical oncology, 2022, Feb-27, Volume: 20, Issue:1

    Topics: Adenosine; Biomarkers, Tumor; Epithelial Cells; Humans; Lung; Lung Neoplasms; Prognosis

2022
Methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit-induced long intergenic non-protein coding RNA 1833 N6-methyladenosine methylation promotes the non-small cell lung cancer progression via regulating heterogeneous nuclear ribon
    Bioengineered, 2022, Volume: 13, Issue:4

    Topics: Adenosine; Animals; Carcinoma, Non-Small-Cell Lung; Catalytic Domain; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Lung Neoplasms; Methylation; Methyltransferases; Mice; RNA, Long Noncoding

2022
N6-methyladenosine (m6A) regulator expression pattern correlates with the immune landscape in lung adenocarcinoma.
    Gene, 2022, Aug-20, Volume: 836

    Topics: Adenocarcinoma of Lung; Adenosine; Humans; Lung Neoplasms; Tumor Microenvironment

2022
Construction and validation of a nomogram based on N6-Methylandenosine-related lncRNAs for predicting the prognosis of non-small cell lung cancer patients.
    Cancer medicine, 2023, Volume: 12, Issue:2

    Topics: Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Nomograms; Prognosis; RNA, Long Noncoding; Tumor Microenvironment

2023
The prognostic value of N6-methyladenosine RBM15 regulators in lung adenocarcinoma.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, May-22, Volume: 68, Issue:1

    Topics: Adenocarcinoma of Lung; Adenosine; Animals; Humans; Lung Neoplasms; Mammals; Prognosis; RNA-Binding Proteins; RNA, Messenger; RNA, Small Interfering

2022
Anesthetic propofol enhances cisplatin-sensitivity of non-small cell lung cancer cells through N6-methyladenosine-dependently regulating the miR-486-5p/RAP1-NF-κB axis.
    BMC cancer, 2022, Jul-14, Volume: 22, Issue:1

    Topics: Adenosine; Anesthetics; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; MicroRNAs; NF-kappa B; Propofol

2022
N6-Methyladenosine Reader YTHDF2 Enhances Non-Small-Cell Lung Cancer Cell Proliferation and Metastasis through Mediating circ_SFMBT2 Degradation.
    Contrast media & molecular imaging, 2022, Volume: 2022

    Topics: Adenosine; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Humans; Lung Neoplasms; Protein Serine-Threonine Kinases; Repressor Proteins; RNA; RNA-Binding Proteins; Transcription Factors; Tumor Suppressor Proteins

2022
A novel algorithm for lung adenocarcinoma based on N6 methyladenosine-related immune long noncoding RNAs as a reliable biomarker for predicting survival outcomes and selecting sensitive anti-tumor therapies.
    Journal of clinical laboratory analysis, 2022, Volume: 36, Issue:9

    Topics: Adenocarcinoma; Adenosine; Algorithms; Antineoplastic Agents; Humans; Lung; Lung Neoplasms; Prognosis; RNA, Long Noncoding; Tumor Microenvironment

2022
Effects of N6-Methyladenosine Regulators on LAG3 and Immune Infiltrates in Lung Adenocarcinoma.
    Disease markers, 2022, Volume: 2022

    Topics: Adenocarcinoma of Lung; Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Antigens, CD; Humans; Lung Neoplasms; Lymphocyte Activation Gene 3 Protein; Prognosis; RNA-Binding Proteins; Tumor Microenvironment; Ubiquitin-Protein Ligases

2022
N
    Molecular cell, 2023, Nov-02, Volume: 83, Issue:21

    Topics: Carcinoma, Non-Small-Cell Lung; HeLa Cells; Humans; Lung Neoplasms; Methyltransferases; Positive Transcriptional Elongation Factor B; RNA Polymerase II; RNA, Small Nuclear; Transcription, Genetic

2023
Dissecting the m
    The pharmacogenomics journal, 2020, Volume: 20, Issue:2

    Topics: A549 Cells; Adenosine; Afatinib; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; Humans; Lung Neoplasms

2020
ALKBH5-m
    Biochemical and biophysical research communications, 2020, 01-08, Volume: 521, Issue:2

    Topics: Adenocarcinoma of Lung; Adenosine; AlkB Homolog 5, RNA Demethylase; Animals; Cell Proliferation; Forkhead Box Protein M1; Humans; Hypoxia; Lung Neoplasms; Mice; Neoplasm Invasiveness; Signal Transduction

2020
N6-methyladenosine induced miR-143-3p promotes the brain metastasis of lung cancer via regulation of VASH1.
    Molecular cancer, 2019, 12-10, Volume: 18, Issue:1

    Topics: Adenosine; Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Epithelial-Mesenchymal Transition; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; MicroRNAs; Models, Biological; Neovascularization, Pathologic; RNA Interference; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2019
Immune signature of T follicular helper cells predicts clinical prognostic and therapeutic impact in lung squamous cell carcinoma.
    International immunopharmacology, 2020, Volume: 81

    Topics: Adenosine; Aged; AlkB Homolog 5, RNA Demethylase; Antineoplastic Agents, Immunological; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Datasets as Topic; Female; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoprotein Group C; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Male; Methylation; Methyltransferases; Middle Aged; Prognosis; RNA-Binding Proteins; RNA-Seq; T Follicular Helper Cells; Transcriptome

2020
N
    Gene, 2020, Mar-20, Volume: 731

    Topics: A549 Cells; Adenosine; AlkB Homolog 5, RNA Demethylase; Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Progression; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; RNA Stability; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-3

2020
N6-Methyladenosine Regulates the Expression and Secretion of TGFβ1 to Affect the Epithelial-Mesenchymal Transition of Cancer Cells.
    Cells, 2020, 01-25, Volume: 9, Issue:2

    Topics: 5' Untranslated Regions; Adenosine; Animals; Cell Movement; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Knockdown Techniques; HeLa Cells; Humans; Lung Neoplasms; Methyltransferases; Mice; Peptide Chain Elongation, Translational; Protein Biosynthesis; Protein Stability; Snail Family Transcription Factors; Transforming Growth Factor beta1

2020
Expression and Prognostic Significance of m6A-Related Genes in Lung Adenocarcinoma.
    Medical science monitor : international medical journal of experimental and clinical research, 2020, Feb-22, Volume: 26

    Topics: Adenocarcinoma of Lung; Adenosine; Cohort Studies; Disease-Free Survival; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Prognosis; RNA, Messenger

2020
Simvastatin is beneficial to lung cancer progression by inducing METTL3-induced m6A modification on EZH2 mRNA.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:8

    Topics: A549 Cells; Adenosine; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Enhancer of Zeste Homolog 2 Protein; Epithelial-Mesenchymal Transition; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung Neoplasms; Methyltransferases; RNA, Messenger; Simvastatin; Tumor Cells, Cultured

2020
KIAA1429 promotes the progression of lung adenocarcinoma by regulating the m6A level of MUC3A.
    Pathology, research and practice, 2021, Volume: 217

    Topics: A549 Cells; Adenocarcinoma of Lung; Adenosine; Cell Movement; Cell Proliferation; Databases, Genetic; Female; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methylation; Middle Aged; Mucin-3; Neoplasm Invasiveness; Neoplasm Staging; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; Signal Transduction; Tumor Burden

2021
Gene signatures of 6-methyladenine regulators in women with lung adenocarcinoma and development of a risk scoring system: a retrospective study using the cancer genome atlas database.
    Aging, 2021, 01-10, Volume: 13, Issue:3

    Topics: Adenocarcinoma of Lung; Adenosine; Databases, Genetic; DNA Copy Number Variations; Early Detection of Cancer; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Middle Aged; Neoplasm Staging; Proportional Hazards Models; Risk Assessment; RNA Processing, Post-Transcriptional; Survival Rate; Transcriptome

2021
N
    Developmental cell, 2021, 03-08, Volume: 56, Issue:5

    Topics: Adenosine; Animals; Apoptosis; Biomarkers, Tumor; Cell Nucleus; Cell Proliferation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; RNA, Long Noncoding; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2021
RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming.
    Nature communications, 2021, 03-02, Volume: 12, Issue:1

    Topics: Adenosine; Animals; Base Sequence; Cell Line, Tumor; Cell Polarity; Cell Proliferation; Cellular Reprogramming; Cytokines; Gene Deletion; Gene Expression Regulation; Lung Neoplasms; Macrophages; Melanoma, Experimental; Methylation; Methyltransferases; Mice, Knockout; Myeloid Cells; Neoplasm Metastasis; NF-kappa B; Programmed Cell Death 1 Receptor; Repressor Proteins; RNA-Binding Proteins; RNA, Neoplasm; STAT3 Transcription Factor; T-Lymphocytes, Regulatory; Tumor Microenvironment

2021
METTL3-mediated m
    Journal of experimental & clinical cancer research : CR, 2021, Mar-06, Volume: 40, Issue:1

    Topics: Adenocarcinoma of Lung; Adenosine; Animals; Cell Line, Tumor; Cell Proliferation; F-Box-WD Repeat-Containing Protein 7; Heterografts; Humans; Lung Neoplasms; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; RNA, Messenger

2021
Exosomal miR-4443 promotes cisplatin resistance in non-small cell lung carcinoma by regulating FSP1 m6A modification-mediated ferroptosis.
    Life sciences, 2021, Jul-01, Volume: 276

    Topics: Adenosine; Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Exosomes; Ferroptosis; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Prognosis; S100 Calcium-Binding Protein A4; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2021
Suppression of m6A mRNA modification by DNA hypermethylated ALKBH5 aggravates the oncological behavior of KRAS mutation/LKB1 loss lung cancer.
    Cell death & disease, 2021, 05-20, Volume: 12, Issue:6

    Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; AMP-Activated Protein Kinase Kinases; Cell Line, Tumor; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mutation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins p21(ras); RNA, Messenger; Transfection

2021
LCAT3, a novel m6A-regulated long non-coding RNA, plays an oncogenic role in lung cancer via binding with FUBP1 to activate c-MYC.
    Journal of hematology & oncology, 2021, 07-17, Volume: 14, Issue:1

    Topics: Adenosine; Animals; Carcinogenesis; Cell Line, Tumor; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice, Inbred BALB C; Neoplasm Invasiveness; Prognosis; Proto-Oncogene Proteins c-myc; RNA-Binding Proteins; RNA, Long Noncoding; Up-Regulation

2021
Cigarette smoking induces aberrant N
    Cancer letters, 2021, 10-10, Volume: 518

    Topics: A549 Cells; Adenosine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cigarette Smoking; Death-Associated Protein Kinases; Disease Progression; Down-Regulation; Gene Expression Regulation; HEK293 Cells; Humans; Lung Neoplasms; NF-kappa B; Nicotiana; Oncogenes; RNA, Messenger; Signal Transduction

2021
Microarray analysis of genes with differential expression of m6A methylation in lung cancer.
    Bioscience reports, 2021, 09-30, Volume: 41, Issue:9

    Topics: Adenosine; Biomarkers, Tumor; DNA Methylation; Epigenome; Epigenomics; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Transcriptome

2021
Characteristic of molecular subtypes in lung adenocarcinoma based on m6A RNA methylation modification and immune microenvironment.
    BMC cancer, 2021, Aug-20, Volume: 21, Issue:1

    Topics: Adenocarcinoma of Lung; Adenosine; Biomarkers, Tumor; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Methylation; Prognosis; RNA Processing, Post-Transcriptional; Survival Rate; Transcriptome; Tumor Microenvironment

2021
N
    Toxicology letters, 2018, Volume: 292

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Apoptosis; Arsenites; Cell Cycle Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Methyltransferases; MicroRNAs; Nuclear Proteins; Phenotype; RNA Splicing Factors; Signal Transduction; Sodium Compounds; Time Factors

2018
m
    Biochemical and biophysical research communications, 2018, 08-25, Volume: 502, Issue:4

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Carcinoma, Squamous Cell; Cell Line, Tumor; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Kruppel-Like Transcription Factors; Lung Neoplasms; Oncogenes; Prognosis; RNA Stability; RNA, Messenger; RNA, Neoplasm

2018
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner.
    Nucleic acids research, 2019, 01-10, Volume: 47, Issue:1

    Topics: Adenosine; Animals; Cell Line, Tumor; Disease-Free Survival; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Lung Neoplasms; Male; Mice; MicroRNAs; Ovarian Neoplasms; RNA-Binding Proteins; Serum Response Factor; Xenograft Model Antitumor Assays

2019
The m6A demethylase FTO promotes the growth of lung cancer cells by regulating the m6A level of USP7 mRNA.
    Biochemical and biophysical research communications, 2019, 05-07, Volume: 512, Issue:3

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; RNA, Messenger; Ubiquitin-Specific Peptidase 7

2019