n-methyladenosine has been researched along with Disease Exacerbation in 76 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 16 (21.05) | 24.3611 |
2020's | 60 (78.95) | 2.80 |
Authors | Studies |
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Chen, J; Dai, Y; Ding, X; Fang, Y; Hu, J; Liang, Y; Liu, H; Lu, Z; Ning, Y; Song, N; Teng, J; Zhu, J; Zou, J | 1 |
Chen, X; Dong, J; Gong, W; Guo, B; Jiang, Q; Qin, J; Shao, X; Shen, S; Shi, T; Shi, Y; Zhang, L | 1 |
Chen, L; Jin, Y; Li, L; Ma, C; Ma, Y; Tang, Y; Xing, M; Yang, D; Yang, J; Zhang, M | 1 |
Liu, X; Ma, T; Meng, L; Tian, Z; Wang, J; Wang, X; Zhang, W; Zhang, Y | 1 |
Dong, S; Li, J; Li, X; Liu, H; Wang, J; Zhang, Y | 1 |
He, A; Jia, Y; Kong, G; Liu, R | 1 |
Ding, J; Qian, K; Xia, X; Xu, W | 1 |
Chen, G; Chen, L; Cheng, H; Deng, T; Fan, Y; Gong, P; Niu, X; Tian, Y; Wang, P; Wang, W; Xiao, H; Yang, L; Yang, Y; Yuan, J; Zhang, J; Zhang, P; Zhang, W; Zhang, X | 1 |
Chao, Y; Ji, W; Jin, H; Lin, S; Min, W; Qi, D; Que, B; Wang, X; Yang, M; Ying, X; Yuan, Z; Zhang, H | 1 |
Shi, J; Wang, H; Xu, B | 1 |
Chen, L; Chen, Z; Deng, Q; Dinglin, X; Hou, X; Huang, H; Li, D; Ling, Y; Lv, Z; Ma, S; Peng, Y; Wang, H; Wu, Y | 1 |
Chen, X; He, B; Liu, X; Pan, B; Pan, Y; Sun, H; Sun, L; Wang, S; Xia, X; Xu, M; Xu, X; Zeng, K | 1 |
Chen, X; Hao, X; Huang, J; Lan, T; Li, H; Li, J; Liao, H; Liao, M; Liu, H; Wu, H; Xie, K; Xu, L; Yan, X; Yuan, K; Zeng, Y; Zhang, D | 1 |
Cai, J; Cao, M; Chen, Z; Gao, W; Wang, J; Wang, X; Wu, J; Zhang, Y; Zuo, X | 1 |
Chen, P; Ma, L; Qian, Q; Zhao, X; Zhu, Z | 1 |
Fang, J; Li, F; Li, Z; Peng, Y; Zhou, J | 1 |
Cui, X; Fan, Y; Li, J; Ren, Z; Sun, R; Wang, Z; Zhang, D; Zhao, W; Zhu, J | 1 |
Chen, F; Chen, Z; Ge, L; Li, D; Li, J; Li, Z; Song, J; Wang, C; Wang, H; Wang, J; Wu, J; Wu, Y; Zhang, N | 1 |
Lin, C; Ye, J; Zhuang, J | 1 |
Bo, X; Jiang, H; Liu, Z; Qin, S; Qu, N; Tan, C; Wen, G; Zhang, X | 1 |
Dai, C; Ding, H; Jia, C; Su, Y; Zhang, X | 1 |
Ban, Y; Cai, J; Hu, M; Li, G; Li, J; Li, X; Mei, Y; Tan, P; Tan, Y; Xiang, B; Xiong, W; Yi, M; Zeng, Z; Zhou, Y | 1 |
Deng, H; Kidwell, RL; Liang, Z; Xie, Q | 1 |
Guo, Y; Li, C; Liu, J; Mao, S; Yao, X; Zhang, W; Zheng, Z | 1 |
Ju, S; Kong, S; Tao, M; Wang, T | 1 |
Chen, Y; Gao, W; He, J; Lin, Y; Shu, Y | 1 |
Feng, D; Han, J; Lu, Q; Lv, J; Wu, Q; Yang, H; Yang, X; Yu, H; Yuan, B; Zhou, Z | 1 |
Chen, W; Huang, S; Huang, X; Li, W; Lin, R; Liu, Q; Shen, H; Shi, Y; Wang, H; Wang, J; Xu, S; Yang, L; Yu, J; Zhan, M; Zhang, Z | 1 |
Chen, C; Guo, Y; Hou, C; Liu, J; Sun, Z; Yin, D; Yuan, W; Zhang, L | 1 |
Chen, YC; Huang, GZ; Lv, XZ; Shao, TR; Wu, QQ; Zeng, WS; Zheng, ZN | 1 |
Chen, TQ; Chen, YQ; Chen, ZH; Fang, K; Han, C; Huang, W; Luo, XQ; Sun, LY; Sun, YM; Wang, D; Wang, WT; Zeng, ZC | 1 |
Cheng, J; Deng, L; Meng, Q; Wang, J; Wei, F; Xu, L; Xue, L | 1 |
Chang, Z; Li, Z; Liu, Y; Lu, X; Luo, C; Qiao, K; Sun, T; Xu, Z; Yang, C; Zhang, C; Zhang, H | 1 |
Huo, FC; Pei, DS; Zhu, ZM | 1 |
Du, C; Feng, Y; Lv, C; Yu, S | 1 |
Cheng, T; Duan, L; Gao, S; Gu, Y; Han, X; Jiang, S; Li, Y; Liu, T; Liu, Y; Niu, S; Pan, Y; Peng, B; Shang, L; Sun, M; Tong, Z; Wang, X; Wang, Y; Yang, X; Yang, Z; Ye, Q; Zhang, C; Zhang, N; Zhang, X | 1 |
Hao, L; Li, C; Liu, L; Yang, H; Yin, J; Zhong, J; Zhu, L | 1 |
Li, J; Li, X; Liang, L; Ma, Y; Yang, Y | 1 |
Gao, Y; Gao, Z; Luo, J; Song, W; Yang, K | 1 |
Chu, J; He, F; He, J; Jia, J; Sheng, J; Wan, J; Wang, C; Yin, H; Yin, J; Zhou, M | 1 |
Li, F; Lin, Y; Liu, S; Lv, S; Wang, H; Wang, S | 1 |
Li, M; Wang, S; Zha, X | 1 |
Chen, R; Hou, G; Huang, C; Jiang, B; Li, L; Liu, X; Lu, R; Wang, Y; Yang, Q; Yu, J; Zhao, X | 1 |
Paramasivam, A; Priyadharsini, JV | 1 |
Lou, X; Sun, JJ; Wang, JJ; Wei, YQ | 1 |
Cheng, Y; Dong, H; Wang, M; Wang, S; Xu, H; Zhou, J | 1 |
Huang, C; Jiang, G; Liu, F; Sun, J; Xiao, X; Xie, F; Zhang, H; Zhang, X | 1 |
Dai, XY; Ding, Q; Huang, YZ; Li, Z; Shi, L; Wei, JF; Yang, HY; Zhang, X | 1 |
Gong, Z; Guo, C; He, Y; Li, G; Li, X; Li, Y; Shi, L; Tan, F; Wang, F; Wang, Y; Xiang, B; Xiong, F; Xiong, W; Zeng, Z; Zhang, S; Zhao, M; Zhou, M | 1 |
An, SY; Chai, RC; Chang, X; Chang, YZ; Jiang, T; Pang, B; Wang, YZ; Zhang, KN | 1 |
Chong, T; Guan, Y; Ma, Y; Xu, F; Xue, L; Yang, X; Zhang, P | 1 |
Fang, R; Shi, H; Ye, L | 1 |
Chen, C; Gan, M; Kong, J; Lai, M; Wang, S; Zhang, H; Zhang, Y | 1 |
Barr, T; Caligiuri, MA; Chen, J; Chen, Z; Ma, S; Sun, JC; Wang, LS; Yan, J; Yu, J; Zhang, J | 1 |
Lv, Y; Tang, M | 1 |
Li, J; Liu, Y; Ni, B; Wang, F; Wang, H | 1 |
He, X; Hu, K; Jin, M; Li, G; Liu, W; Song, Y; Wu, X; Xiong, M; Zeng, Z; Zhang, Q; Zhao, D; Zhu, J | 1 |
Liu, Y; Ou, B; Xu, X; Yan, Y; Yang, X; Zhang, J | 1 |
Jiang, XB; Li, XD; Wang, MJ; Wang, X; Wu, YH; Zheng, JL | 1 |
Chen, X; Jiang, J; Li, D; Wang, A; Yang, L | 1 |
Abisambra, JF; Alvarez, VE; Ash, PEA; Boudeau, S; Cheng, JX; Crary, JF; Cruz, AL; Emili, A; Hovde, S; Jiang, L; Kanaan, N; Kuo, MH; Kwan, J; Lei, S; Li, H; Lin, W; Maziuk, BF; Murray, ME; Petrucelli, L; Song, J; van Vliet, E; Verma, M; Wolozin, B; Yang, Z; Zhang, C; Zhao, J | 1 |
Dai, D; Jin, H; Wang, H; Wang, X; Zhu, L | 1 |
Du, Z; Jin, Y; Liu, J; Ren, D; Wang, H; Zhang, H | 1 |
Chai, P; Jia, R; Wang, S | 1 |
He, L; Li, J; Wang, X; Xie, H; Xie, L; Yan, H; Ying, Y; Zheng, X | 1 |
Chen, J; Du, B | 1 |
He, Q; Hong, M; Lei, Y; Li, Y; Liu, N; Ma, J; Ren, X; Wang, Y; Wen, X; Yang, X; Zhang, J; Zhang, P | 1 |
Chen, B; Li, Y; Song, R; Xu, F; Xue, C | 2 |
Chen, H; Li, X; Liang, H; Lin, Z; Niu, Y; Sun, L; Wan, A; Wan, G; Wang, Y; Wei, B; Wu, X; Xiong, XF | 1 |
Liu, W; Ning, J; Wu, D; Wu, L; Zhang, D | 1 |
Bai, R; Che, X; Chen, R; Fu, Z; Jia, W; Li, G; Li, M; Li, S; Lin, D; Liu, Z; Mai, D; Pan, L; Su, J; Tan, L; Tan, W; Wang, C; Wu, C; Xie, D; Xu, RH; Ye, H; Ye, Y; Zeng, MS; Zhang, J; Zhao, Q; Zheng, J; Zheng, S; Zheng, Y; Zuo, Z | 1 |
Cheng, YP; Liang, GY; Liu, T; Pu, YP; Shen, B; Sui, J; Xu, SY; Yang, S; Yin, LH; Zhang, XM; Zhang, Y | 1 |
Chen, J; Jia, L; Ma, J; Miao, W; Song, D | 1 |
Chen, RY; Han, CH; Mou, S; Wu, JJ; Xia, L; Xu, Y; Yuan, XD; Zhang, M | 1 |
Cui, Q; He, C; Huang, Y; Li, L; Lu, Z; Qu, Q; Riggs, AD; Shi, H; Shi, Y; Sun, G; Yang, CG; Ye, P | 1 |
21 review(s) available for n-methyladenosine and Disease Exacerbation
Article | Year |
---|---|
Novel insights into roles of N6-methyladenosine reader YTHDF2 in cancer progression.
Topics: Adenosine; Disease Progression; Humans; Neoplasms; RNA; RNA-Binding Proteins; Transcription Factors | 2022 |
Epigenetic N6-methyladenosine modification of RNA and DNA regulates cancer.
Topics: Adenosine; Antineoplastic Agents; Carcinogenesis; Disease Progression; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Methyltransferases; Neoplasms; Oxidoreductases, N-Demethylating; RNA Processing, Post-Transcriptional; RNA Splicing Factors; RNA-Binding Proteins | 2020 |
The potential role of RNA N6-methyladenosine in Cancer progression.
Topics: Adenosine; Animals; Biomarkers, Tumor; Disease Progression; DNA Methylation; Epigenesis, Genetic; Humans; Methyltransferases; Neoplasms | 2020 |
Interaction between N
Topics: Adenosine; Animals; Biomarkers, Tumor; Disease Progression; DNA Methylation; Epigenesis, Genetic; Humans; Methyltransferases; Neoplasms; RNA, Untranslated | 2020 |
Mechanism of RNA modification N6-methyladenosine in human cancer.
Topics: Adenosine; Biomarkers, Tumor; Disease Progression; DNA Methylation; Epigenesis, Genetic; Humans; Methyltransferases; Neoplasms | 2020 |
The role of N
Topics: Adenosine; Animals; Disease Progression; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Methyltransferases; Neoplasms; RNA, Circular | 2020 |
N
Topics: Adenosine; Animals; Disease Progression; Humans; Methylation; Methyltransferases; Neoplasms; RNA, Messenger | 2020 |
N
Topics: Adenosine; Animals; Biomarkers, Tumor; Colorectal Neoplasms; Disease Progression; Humans; RNA, Messenger; RNA, Untranslated | 2021 |
The role of N6-methyladenosine mRNA in the tumor microenvironment.
Topics: Adenosine; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Neoplastic Stem Cells; RNA, Messenger; Tumor Microenvironment | 2021 |
Emerging role of RNA modification N6-methyladenosine in immune evasion.
Topics: Adenosine; Disease Progression; Humans; Immune Evasion; RNA | 2021 |
The Important Role of N6-methyladenosine RNA Modification in Non-Small Cell Lung Cancer.
Topics: Adenosine; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Disease Progression; Drug Resistance, Neoplasm; Epigenesis, Genetic; Humans; Lung Neoplasms; Prognosis; RNA | 2021 |
N6-methyladenosine-dependent signalling in cancer progression and insights into cancer therapies.
Topics: Adenosine; Disease Progression; Humans; Neoplasms; Signal Transduction | 2021 |
Understanding the roles of N
Topics: Adenosine; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Metastasis; RNA, Messenger | 2021 |
The Role of
Topics: Adenosine; Animals; Disease Progression; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; RNA, Circular | 2021 |
N
Topics: Adenosine; Biomarkers, Tumor; Carcinogenesis; Disease Progression; Humans; Pancreatic Neoplasms; Prognosis; RNA, Messenger | 2021 |
N6-methyladenosine links RNA metabolism to cancer progression.
Topics: Adenosine; Animals; Disease Progression; DNA Damage; Humans; Neoplasms; RNA, Long Noncoding; RNA, Neoplasm | 2018 |
Novel insights on m
Topics: Adenosine; Carcinogenesis; Disease Progression; Gene Regulatory Networks; Humans; Neoplasms; RNA, Messenger | 2018 |
The dual role of N6-methyladenosine modification of RNAs is involved in human cancers.
Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Carcinogenesis; Disease Progression; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genetic Therapy; Humans; Methylation; Methyltransferases; Molecular Targeted Therapy; Neoplasms; RNA Editing; RNA, Neoplasm | 2018 |
Novel positioning from obesity to cancer: FTO, an m
Topics: 3' Untranslated Regions; Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Body Mass Index; Cell Proliferation; Demethylation; Disease Progression; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation; Humans; Neoplasm Metastasis; Neoplasms; Obesity; Oncogenes; Polymorphism, Single Nucleotide; Prognosis; Radiation Tolerance | 2019 |
Functions of RNA N6-methyladenosine modification in cancer progression.
Topics: Adenosine; Animals; Disease Progression; Humans; Methylation; Neoplasms; RNA | 2019 |
Functions of RNA N6-methyladenosine modification in cancer progression.
Topics: Adenosine; Disease Progression; Humans; Methylation; Methyltransferases; Neoplasms; RNA; RNA Processing, Post-Transcriptional | 2019 |
55 other study(ies) available for n-methyladenosine and Disease Exacerbation
Article | Year |
---|---|
METTL14 aggravates podocyte injury and glomerulopathy progression through N
Topics: Adenosine; Animals; Apoptosis; Autophagy; Cytoprotection; Diabetic Nephropathies; Disease Progression; Down-Regulation; Doxorubicin; Gene Silencing; Glycation End Products, Advanced; Inflammation; Male; Methyltransferases; Mice, Inbred C57BL; Models, Biological; Podocytes; RNA, Messenger; Sirtuin 1; Up-Regulation | 2021 |
METTL3-mediated m
Topics: Adenosine; Animals; Autophagy; Autophagy-Related Protein 7; Cartilage, Articular; Cell Line; Cellular Senescence; Chondrocytes; Coculture Techniques; Disease Models, Animal; Disease Progression; Female; GATA4 Transcription Factor; Gene Expression; Humans; Immunoprecipitation; Male; Methylation; Methyltransferases; Mice; Middle Aged; Osteoarthritis; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Messenger; RNA, Small Interfering; Synoviocytes; Up-Regulation | 2022 |
m
Topics: 3' Untranslated Regions; Adenosine; Aged; Aged, 80 and over; Apoptosis; Aquaporin 1; Cartilage, Articular; Cells, Cultured; Chondrocytes; Disease Progression; Extracellular Matrix; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; MicroRNAs; Middle Aged; Models, Biological; Osteoarthritis; Phosphate Transport Proteins; RNA Interference; RNA, Long Noncoding | 2021 |
An effective N6-methyladenosine-related long non-coding RNA prognostic signature for predicting the prognosis of patients with bladder cancer.
Topics: Adenosine; Disease Progression; Humans; Immune Checkpoint Proteins; Lymphocytes, Tumor-Infiltrating; Neoplasm Staging; Prognosis; Proportional Hazards Models; RNA-Seq; RNA, Long Noncoding; Survival Rate; Transcriptome; Treatment Outcome; Urinary Bladder Neoplasms | 2021 |
ALKBH5 Is Lowly Expressed in Esophageal Squamous Cell Carcinoma and Inhibits the Malignant Proliferation and Invasion of Tumor Cells.
Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Apoptosis; Cell Line, Tumor; Cell Proliferation; Computational Biology; Disease Progression; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Invasiveness; Recombinant Proteins; Transfection | 2021 |
Methyltransferase-like 3 (METTL3) mediated N6-methyladenosine (m6A) modifications facilitate mir-25-3p maturation to promote gastrointestinal stromal tumors (GISTs) progression.
Topics: Adenosine; Disease Progression; Gastrointestinal Stromal Tumors; Humans; Methyltransferases; MicroRNAs | 2022 |
Crosstalk between 5-methylcytosine and N
Topics: 5-Methylcytosine; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Progression; G2 Phase Cell Cycle Checkpoints; Humans; Liver Neoplasms; Pharmacogenetics | 2023 |
N
Topics: Adenosine; Adult; Aged; AlkB Homolog 5, RNA Demethylase; Animals; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Integrin alpha6; Male; Methyltransferases; Mice; Middle Aged; Neoplasm Grading; Neoplasm Staging; RNA, Messenger; Urinary Bladder Neoplasms | 2019 |
N6-methyladenosine METTL3 promotes the breast cancer progression via targeting Bcl-2.
Topics: Adenosine; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Progression; Female; Humans; Methyltransferases; Proto-Oncogene Proteins c-bcl-2 | 2020 |
N6-methyladenosine induced miR-143-3p promotes the brain metastasis of lung cancer via regulation of VASH1.
Topics: Adenosine; Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Epithelial-Mesenchymal Transition; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; MicroRNAs; Models, Biological; Neovascularization, Pathologic; RNA Interference; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2019 |
RETRACTED: METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing
Topics: Adenosine; Animals; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Methyltransferases; Mice; MicroRNAs; RNA Interference; Xenograft Model Antitumor Assays | 2020 |
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3.
Topics: Adenosine; Animals; Cell Line, Tumor; Disease Models, Animal; Disease Progression; GATA3 Transcription Factor; Humans; Liver Neoplasms; Methylation; Mice; Models, Biological; Neoplasm Metastasis; Prognosis; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Antisense; RNA, Long Noncoding; Xenograft Model Antitumor Assays | 2019 |
M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma.
Topics: Adenosine; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Progression; Gene Expression Regulation, Neoplastic; Genetic Therapy; Humans; Lipogenesis; Liver Neoplasms; Mice, Inbred BALB C; Mice, SCID; RNA, Long Noncoding; Up-Regulation | 2020 |
N
Topics: A549 Cells; Adenosine; AlkB Homolog 5, RNA Demethylase; Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Progression; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; RNA Stability; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-3 | 2020 |
Identification of three m6A-related mRNAs signature and risk score for the prognostication of hepatocellular carcinoma.
Topics: Adenosine; Biomarkers, Tumor; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line, Tumor; Datasets as Topic; Disease Progression; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Methylation; Methyltransferases; Nomograms; Risk Factors; RNA, Messenger; ROC Curve; Suppressor of Cytokine Signaling Proteins; Transaminases | 2020 |
Cross talk between RNA N6-methyladenosine methyltransferase-like 3 and miR-186 regulates hepatoblastoma progression through Wnt/β-catenin signalling pathway.
Topics: Adenosine; Animals; Disease Progression; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hepatoblastoma; Humans; Liver Neoplasms; Male; Methyltransferases; Mice, Inbred C57BL; Mice, Nude; MicroRNAs; Prognosis; Wnt Signaling Pathway | 2020 |
Level of N6-Methyladenosine in Peripheral Blood RNA: A Novel Predictive Biomarker for Gastric Cancer.
Topics: Adenosine; Adult; Aged; AlkB Homolog 5, RNA Demethylase; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Antigens, Tumor-Associated, Carbohydrate; Area Under Curve; Biomarkers, Tumor; Carcinoembryonic Antigen; Disease Progression; Female; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; RNA, Messenger; Stomach Neoplasms; Xenograft Model Antitumor Assays | 2020 |
m
Topics: Adenosine; Adult; Aged; Biomarkers, Tumor; Disease Progression; Disease-Free Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; Middle Aged; Prognosis; Proportional Hazards Models; Protein Interaction Maps; Rectal Neoplasms; RNA; RNA Helicases; RNA-Binding Proteins; Transcriptome | 2020 |
Multiple m
Topics: Adenosine; Biomarkers, Tumor; Carcinoma, Hepatocellular; Disease Progression; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Methyltransferases; Neoplasm Grading; Prognosis; RNA-Binding Proteins; Sequence Analysis, RNA | 2020 |
GNAS promotes inflammation-related hepatocellular carcinoma progression by promoting STAT3 activation.
Topics: Adenosine; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromogranins; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; GTP-Binding Protein alpha Subunits, Gs; Humans; Inflammation; Interleukin-6; Lipopolysaccharides; Liver Neoplasms; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; RNA Interference; RNA, Long Noncoding; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2020 |
LNCAROD is stabilized by m6A methylation and promotes cancer progression via forming a ternary complex with HSPA1A and YBX1 in head and neck squamous cell carcinoma.
Topics: Adenosine; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; HSP70 Heat-Shock Proteins; Humans; Male; Methylation; Methyltransferases; Middle Aged; Models, Biological; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Proteasome Endopeptidase Complex; Proteolysis; RNA Stability; RNA, Long Noncoding; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Y-Box-Binding Protein 1 | 2020 |
N6‑methyladenosine RNA methylation regulators participate in malignant progression and have prognostic value in clear cell renal cell carcinoma.
Topics: Adenosine; Biomarkers, Tumor; Carcinoma, Renal Cell; Cell Line, Tumor; Disease Progression; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Male; Neoplasm Staging; Nomograms; Sequence Analysis, RNA; Survival Analysis | 2020 |
Deoxycholic acid modulates the progression of gallbladder cancer through N
Topics: Adenosine; Animals; Cell Line, Tumor; Cell Proliferation; Deoxycholic Acid; Disease Progression; Gallbladder Neoplasms; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Male; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; RNA Interference; Xenograft Model Antitumor Assays | 2020 |
M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT.
Topics: Adenosine; Biomarkers, Tumor; Carcinogenesis; Cluster Analysis; Computational Biology; Datasets as Topic; Disease Progression; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoprotein Group C; Humans; Male; Methylation; Middle Aged; Mouth Neoplasms; Principal Component Analysis; Prognosis; Risk Assessment; RNA Processing, Post-Transcriptional; RNA, Messenger; Squamous Cell Carcinoma of Head and Neck | 2020 |
Nuclear export of chimeric mRNAs depends on an lncRNA-triggered autoregulatory loop in blood malignancies.
Topics: Active Transport, Cell Nucleus; Adenosine; Animals; Cell Line, Tumor; Cell Nucleus; Disease Progression; Gene Expression Regulation, Leukemic; Gene Rearrangement; Humans; Leukemia; Male; Methyltransferases; Mice, Inbred NOD; Mice, SCID; Models, Biological; Nerve Tissue Proteins; Oncogene Proteins, Fusion; RNA Splicing Factors; RNA, Long Noncoding; RNA, Messenger; Serine-Arginine Splicing Factors | 2020 |
RNA N
Topics: 3' Untranslated Regions; Adenosine; Adult; Apoptosis; Biomarkers, Tumor; Case-Control Studies; Cell Differentiation; Cell Proliferation; Disease Progression; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; N-Myc Proto-Oncogene Protein; Neoplasm Invasiveness; Neuroblastoma; Prognosis; RNA, Neoplasm; Survival Rate; Tumor Cells, Cultured | 2020 |
RNA m6A methylation promotes the formation of vasculogenic mimicry in hepatocellular carcinoma via Hippo pathway.
Topics: Adaptor Proteins, Signal Transducing; Adenosine; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Silencing; Hippo Signaling Pathway; Humans; Liver Neoplasms; Methylation; Methyltransferases; Mice, Inbred BALB C; Mice, Nude; Molecular Mimicry; Prognosis; Protein Biosynthesis; Protein Serine-Threonine Kinases; RNA; RNA, Messenger; Signal Transduction; Transcription Factors; Xenograft Model Antitumor Assays; YAP-Signaling Proteins | 2021 |
Activation of the KDM5A/miRNA-495/YTHDF2/m6A-MOB3B axis facilitates prostate cancer progression.
Topics: Adenosine; Animals; Apoptosis; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Microtubule-Associated Proteins; Prognosis; Prostatic Neoplasms; Retinoblastoma-Binding Protein 2; RNA-Binding Proteins; Survival Rate; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
Topics: Adenosine; Animals; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 4; Disease Progression; DNA Methylation; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Kidney Neoplasms; Methyltransferases; Mice; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; RNA-Binding Proteins; RNA, Long Noncoding | 2021 |
ALKBH5-mediated m
Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Demethylation; Disease Progression; Epithelial-Mesenchymal Transition; Forkhead Box Protein M1; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; RNA Processing, Post-Transcriptional; RNA Stability; RNA, Messenger; Uveal Neoplasms | 2021 |
Dysregulation of USP18/FTO/PYCR1 signaling network promotes bladder cancer development and progression.
Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Carcinogenesis; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; delta-1-Pyrroline-5-Carboxylate Reductase; Disease Progression; Gene Knock-In Techniques; Gene Knockdown Techniques; Humans; Methylation; Mice; Neoplasm Staging; Neoplasm Transplantation; Pyrroline Carboxylate Reductases; RNA Processing, Post-Transcriptional; RNA Stability; RNA, Messenger; Ubiquitin Thiolesterase; Urinary Bladder Neoplasms | 2021 |
METTL3 restrains papillary thyroid cancer progression via m
Topics: Adenosine; Animals; Disease Progression; Down-Regulation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Male; Methyltransferases; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neutrophil Infiltration; Prognosis; Proto-Oncogene Proteins c-rel; Sequence Analysis, RNA; Thyroid Cancer, Papillary; Thyroid Neoplasms | 2021 |
Identification and Verification of Molecular Subtypes with Enhanced Immune Infiltration Based on m6A Regulators in Cutaneous Melanoma.
Topics: Adenosine; Disease Progression; DNA Copy Number Variations; Gene Expression Regulation, Neoplastic; Genomics; Humans; Melanoma; Polymorphism, Single Nucleotide; Skin Neoplasms; Transcriptome; Unsupervised Machine Learning | 2021 |
SUMOylation of YTHDF2 promotes mRNA degradation and cancer progression by increasing its binding affinity with m6A-modified mRNAs.
Topics: Adenosine; Animals; Cell Hypoxia; Cell Line; Disease Progression; Humans; Lysine; Male; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oxidative Stress; RNA Stability; RNA-Binding Proteins; RNA, Messenger; Small Ubiquitin-Related Modifier Proteins; Sumoylation; Transcriptome; Ubiquitination | 2021 |
RNA N6-methyladenosine: a new player in autophagy-mediated anti-cancer drug resistance.
Topics: Adenosine; Autophagy; Disease Progression; Drug Resistance, Neoplasm; Humans; Methylation; Methyltransferases; Neoplasms; RNA; RNA Processing, Post-Transcriptional | 2021 |
CircPTPRA blocks the recognition of RNA N
Topics: Adenosine; Animals; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Disease Progression; Epigenesis, Genetic; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Heterografts; Humans; Immunohistochemistry; Mice; Models, Biological; Protein Binding; Receptor-Like Protein Tyrosine Phosphatases, Class 4; RNA-Binding Proteins; RNA, Circular; Urinary Bladder Neoplasms | 2021 |
CircMETTL3, upregulated in a m6A-dependent manner, promotes breast cancer progression.
Topics: Adenosine; Breast Neoplasms; Carcinogenesis; CDC2 Protein Kinase; Cell Movement; Cell Proliferation; Disease Progression; Drug Discovery; Gene Expression Regulation, Neoplastic; Humans; Methyltransferases; MicroRNAs; Neoplasm Invasiveness; RNA, Circular; Signal Transduction | 2021 |
METTL3 enhances the stability of MALAT1 with the assistance of HuR via m6A modification and activates NF-κB to promote the malignant progression of IDH-wildtype glioma.
Topics: Adenosine; Animals; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Disease Progression; ELAV-Like Protein 1; Female; Glioma; Heterografts; Humans; Isocitrate Dehydrogenase; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; RNA, Long Noncoding; Signal Transduction | 2021 |
Bioinformatic analyses and experimental validation of the role of m6A RNA methylation regulators in progression and prognosis of adrenocortical carcinoma.
Topics: Adenosine; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Computational Biology; Datasets as Topic; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoprotein Group C; Humans; Immune Checkpoint Inhibitors; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nomograms; RNA; RNA-Binding Proteins; Survival Analysis; Survival Rate; Tumor Microenvironment | 2021 |
Methyl CpG binding protein 2 promotes colorectal cancer metastasis by regulating N
Topics: Adenosine; Animals; Cell Line, Tumor; Colorectal Neoplasms; Disease Progression; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Methyl-CpG-Binding Protein 2; Methyltransferases; Mice; Neoplasm Transplantation; RNA Stability; Up-Regulation | 2021 |
The RNA m6A reader YTHDF2 controls NK cell antitumor and antiviral immunity.
Topics: Adenosine; Animals; Antiviral Agents; Cell Proliferation; Cell Survival; Cytomegalovirus Infections; Disease Progression; DNA-Binding Proteins; Homeostasis; Immunity; Interleukin-15; Killer Cells, Natural; Mice, Inbred C57BL; Neoplasms; RNA; RNA-Binding Proteins; Transcriptome | 2021 |
Cigarette smoking induces aberrant N
Topics: A549 Cells; Adenosine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cigarette Smoking; Death-Associated Protein Kinases; Disease Progression; Down-Regulation; Gene Expression Regulation; HEK293 Cells; Humans; Lung Neoplasms; NF-kappa B; Nicotiana; Oncogenes; RNA, Messenger; Signal Transduction | 2021 |
C5aR1-positive neutrophils promote breast cancer glycolysis through WTAP-dependent m6A methylation of ENO1.
Topics: Adenosine; Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Disease Progression; DNA-Binding Proteins; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Male; Metabolome; Methylation; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Neutrophils; Phosphopyruvate Hydratase; Phosphorylation; Principal Component Analysis; Promoter Regions, Genetic; Protein Stability; Receptor, Anaphylatoxin C5a; RNA Splicing Factors; Signal Transduction; Stochastic Processes; Survival Analysis; Tumor Suppressor Proteins; Up-Regulation | 2021 |
Long noncoding RNA just proximal to X-inactive specific transcript facilitates aerobic glycolysis and temozolomide chemoresistance by promoting stability of PDK1 mRNA in an m6A-dependent manner in glioblastoma multiforme cells.
Topics: Adenosine; Aerobiosis; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Demethylation; Disease Progression; Drug Resistance, Neoplasm; Glioblastoma; Glycolysis; Humans; Neoplasm Proteins; Prognosis; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; RNA, Long Noncoding; RNA, Messenger; Temozolomide | 2021 |
METTL3-mediated m6A methylation of ASPM drives hepatocellular carcinoma cells growth and metastasis.
Topics: Adenosine; Apoptosis; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Disease Progression; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Methyltransferases; Nerve Tissue Proteins; Prognosis; Survival Rate; Tumor Cells, Cultured | 2021 |
Interaction of tau with HNRNPA2B1 and N
Topics: Adenosine; Aged; Aged, 80 and over; Alzheimer Disease; Animals; Case-Control Studies; Cerebral Cortex; Disease Models, Animal; Disease Progression; Female; HEK293 Cells; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Male; Methylation; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Protein Aggregates; Protein Aggregation, Pathological; RNA; RNA Processing, Post-Transcriptional; Severity of Illness Index; tau Proteins | 2021 |
m
Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Carcinoma, Squamous Cell; Cell Line, Tumor; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Kruppel-Like Transcription Factors; Lung Neoplasms; Oncogenes; Prognosis; RNA Stability; RNA, Messenger; RNA, Neoplasm | 2018 |
m
Topics: Adenosine; Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Fibroblast Growth Factors; Gene Expression Regulation, Neoplastic; Humans; Methyltransferases; Mice; Mice, Nude; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Signal Transduction; Survival Analysis; Transcription Factors; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2018 |
RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3.
Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Cell Movement; Cell Proliferation; Demethylation; Disease Progression; Epigenesis, Genetic; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplasm Invasiveness; Prognosis; Proto-Oncogene Proteins; Survival Rate; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
Changes of N6-methyladenosine modulators promote breast cancer progression.
Topics: Adenosine; Adult; Breast; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Datasets as Topic; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Methylation; Methyltransferases; Middle Aged; Mutation; Oxidoreductases, N-Demethylating; Prognosis; RNA, Messenger | 2019 |
Excessive miR-25-3p maturation via N
Topics: Adenosine; Adult; Aged; Aged, 80 and over; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Transformation, Neoplastic; Co-Repressor Proteins; Disease Progression; DNA Methylation; Epithelial Cells; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Male; Methyltransferases; MicroRNAs; Middle Aged; Nicotiana; Nuclear Proteins; Pancreatic Ducts; Pancreatic Neoplasms; Phosphoprotein Phosphatases; Prognosis; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Repressor Proteins; Ribosomal Protein S6 Kinases, 70-kDa; RNA-Binding Proteins; Smoke; Smoking; Up-Regulation | 2019 |
Dysregulated N6-methyladenosine methylation writer METTL3 contributes to the proliferation and migration of gastric cancer.
Topics: Actins; Adenosine; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Databases, Genetic; Disease Progression; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Profiling; Humans; Male; Methyltransferases; Neoplasm Staging; Prognosis; RNA Interference; RNA, Messenger; RNA, Small Interfering; Stomach Neoplasms; Transcription Factors | 2020 |
The m6A methyltransferase METTL3 promotes osteosarcoma progression by regulating the m6A level of LEF1.
Topics: Adenosine; Adolescent; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Child; Disease Progression; Humans; Lymphoid Enhancer-Binding Factor 1; Methylation; Methyltransferases; Osteosarcoma; RNA Interference; RNA, Messenger; Wnt Signaling Pathway | 2019 |
The N6-methyladenosine mRNA methylase METTL14 promotes renal ischemic reperfusion injury via suppressing YAP1.
Topics: Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Animals; Cell Cycle Proteins; Disease Progression; DNA Methylation; Humans; Male; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Knockout; Protective Agents; Reperfusion Injury; Signal Transduction; Transcription Factors; YAP-Signaling Proteins | 2020 |
m
Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Base Sequence; Brain Neoplasms; Carcinogenesis; Cell Differentiation; Cell Proliferation; Cell Self Renewal; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; Humans; Meclofenamic Acid; Methylation; Methyltransferases; Mice; Neoplastic Stem Cells; RNA; RNA, Messenger | 2017 |