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n-methyl-n-(1-methyl-4-pyrrolidino-2-butynyl)acetamide and Muscle Contraction

n-methyl-n-(1-methyl-4-pyrrolidino-2-butynyl)acetamide has been researched along with Muscle Contraction in 6 studies

*Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. [MeSH]

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hacksell, U; Nilsson, BM; Vargas, HM1
Hacksell, U; Lundkvist, JR; Ringdahl, B1
Hacksell, U; Nilsson, BM; Ringdahl, B1
Alberts, P; Bartfai, T; Nordström, O; Undén, A; Westlind, A1
Gillberg, PG; Hacksell, U; Modiri, AR; Nilsson, BM; Nilvebrant, L; Sundquist, S1
Caldirola, P; Hacksell, U; Lundkvist, JR; Ringdahl, B; Vargas, HM1

Other Studies

6 other study(ies) available for n-methyl-n-(1-methyl-4-pyrrolidino-2-butynyl)acetamide and Muscle Contraction

ArticleYear
Urea and 2-imidazolidone derivatives of the muscarinic agents oxotremorine and N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide.
    Journal of medicinal chemistry, 1992, Aug-21, Volume: 35, Issue:17

    Topics: Animals; Cerebral Cortex; Guinea Pigs; Ileum; Imidazoles; Molecular Structure; Muscarinic Antagonists; Muscle Contraction; Oxotremorine; Parasympathomimetics; Pyrrolidines; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Urea

1992
Conformationally restricted analogues of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:4

    Topics: Animals; Biological Assay; Cerebral Cortex; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Mice; Molecular Conformation; Muscle Contraction; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Pyrrolidines; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Tremor

1989
Derivatives of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:3

    Topics: Acetamides; Animals; Fluoroacetates; Guinea Pigs; Ileum; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mice; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Pyrrolidines; Receptors, Muscarinic; Structure-Activity Relationship

1988
Presynaptic antagonist-postsynaptic agonist at muscarinic cholinergic synapses. N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide.
    Molecular pharmacology, 1983, Volume: 24, Issue:1

    Topics: Acetylcholine; Animals; Binding, Competitive; Cyclic GMP; Guinea Pigs; Hippocampus; Humans; In Vitro Techniques; Lymphocytes; Male; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Parasympathomimetics; Pyrrolidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Synapses

1983
Pharmacological characterisation of the enantiomers of BM-5, a muscarinic partial agonist with opposed enantioselectivity between affinity and efficacy.
    Pharmacology & toxicology, 2000, Volume: 86, Issue:1

    Topics: Animals; Binding, Competitive; Cats; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Kinetics; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Pyrrolidines; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Stereoisomerism; Tritium; Urinary Bladder

2000
Resolved pyrrolidine, piperidine, and perhydroazepine analogues of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:12

    Topics: Animals; Azepines; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Magnetic Resonance Spectroscopy; Male; Molecular Conformation; Molecular Structure; Muscle Contraction; N-Methylscopolamine; Parasympathomimetics; Piperidines; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Stereoisomerism

1990