n-methyl-3,4-methylenedioxyamphetamine has been researched along with Pregnancy in 64 studies
N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Stimulant use, including cocaine, methamphetamines, ecstasy, and prescription stimulants, in pregnancy is increasingly common." | 5.01 | Stimulant Use in Pregnancy: An Under-recognized Epidemic Among Pregnant Women. ( Gordon, AJ; Metz, TD; Smid, MC, 2019) |
| " One of such drugs is MDMA (3,4-methylenedioxymethamphetamine) or ecstasy due to its high consumption in relevant age and sex groups and its adverse effects on human and rodent developing brains." | 2.66 | Developmental neurotoxicity of MDMA. A systematic literature review summarized in a putative adverse outcome pathway. ( Barenys, M; Fritsche, E; Gómez-Catalán, J; Masjosthusmann, S; Reverte, I, 2020) |
| "Multiple neurological complications of cocaine abuse have been described including both ischemic and hemorrhagic cerebrovascular events, atrophy in the case of chronic abuse, and an increase in incidence of congenital malformations in the setting of maternal use." | 2.43 | Neuroimaging in drug and substance abuse part I: cocaine, cannabis, and ecstasy. ( Borne, J; Cuellar, H; Riascos, R; Rojas, R; Vargas, D, 2005) |
| "These results suggest that MDMA treatment during pregnancy and lactation causes growth retardation and dysfunction of motor neurons in mouse pups." | 1.40 | Maternal MDMA administration in mice leads to neonatal growth delay. ( Kaizaki, A; Numazawa, S; Tanaka, S; Yoshida, T, 2014) |
| "Acute myocardial infarction is rare in pregnancy; however, the emerging trend towards advanced maternal age and the rising prevalence of obesity and diabetes suggest that more cases of myocardial infarction are likely to be encountered in pregnancy." | 1.39 | Acute myocardial infarction in pregnancy following unlicensed use of methylenedioxymethamphetamine ('Ecstasy'). ( Dutton, P; Okunoye, GO, 2013) |
| "One of the most common drug abused by pregnant women is methamphetamine (MA), which is also the most frequently abused illicit drug in the Czech Republic." | 1.38 | Do prenatally methamphetamine-exposed adult male rats display general predisposition to drug abuse in the conditioned place preference test? ( Hrubá, L; Macúchová, E; Nová, E; Pometlová, M; Rokyta, R; Schutová, B; Šlamberová, R, 2012) |
| " Little is known about toxic effects of MDMA and potential underlying molecular mechanisms in the developing brain." | 1.36 | Neurotoxic effects of MDMA (ecstasy) on the developing rodent brain. ( Bendix, I; Brait, D; Dzietko, M; Endesfelder, S; Felderhoff-Mueser, U; Hansen, HH; Klaus, J; Sifringer, M, 2010) |
| "Polydrug use in pregnancy is harmful." | 1.36 | [Maternal and obstetrical data in a retrospective cohort of 170 newborns from polydrug using mothers, in the Paris area, 1999-2008]. ( Crenn-Hebert, C; Genest, L; Lejeune, C; Miossec, E; Simmat-Durand, L; Simonpoli, AM; Toutain, S; Vellut, N, 2010) |
| "3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) is a powerful releaser of 5-HT and chronic use of this drug can cause depletion of monoamines." | 1.35 | Developmental exposure to 3,4-methylenedioxymethamphetamine results in downregulation of neurogenesis in the adult mouse hippocampus. ( Cho, KO; Chung, SY; Kim, SY; Kwack, SJ; Rhee, GS, 2008) |
| " The effects were seen when the drug was administered twice per day, but the optimal dosing regimen is unknown." | 1.34 | Developmental effects of +/-3,4-methylenedioxymethamphetamine on spatial versus path integration learning: effects of dose distribution. ( Schaefer, TL; Vorhees, CV; Williams, MT, 2007) |
| "Increased risk of ventricular septal defect was found to be associated with consumption of cough and cold remedies [pre-conception OR 2." | 1.32 | A case control study to examine the pharmacological factors underlying ventricular septal defects in the North of England. ( Bateman, DN; Dickinson, D; Matthews, JN; McElhatton, PR; O'Keeffe, M; Thomas, SH; Wren, C, 2004) |
| "They also prevent METH-induced reactive gliosis in dopaminergic cultures." | 1.29 | Involvement of oxidative and L-arginine-NO pathways in the neurotoxicity of drugs of abuse in vitro. ( Cadet, JL; Cerruti, C; Epstein, CJ; Ladenheim, B; Sheng, P, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (14.06) | 18.2507 |
| 2000's | 26 (40.63) | 29.6817 |
| 2010's | 26 (40.63) | 24.3611 |
| 2020's | 3 (4.69) | 2.80 |
| Authors | Studies |
|---|---|
| Siegel, JS | 2 |
| Daily, JE | 2 |
| Perry, DA | 2 |
| Nicol, GE | 2 |
| Barenys, M | 4 |
| Reverte, I | 1 |
| Masjosthusmann, S | 1 |
| Gómez-Catalán, J | 3 |
| Fritsche, E | 1 |
| Costa, G | 1 |
| Spulber, S | 1 |
| Paci, E | 1 |
| Casu, MA | 1 |
| Ceccatelli, S | 1 |
| Simola, N | 1 |
| Morelli, M | 1 |
| Macúchová, E | 3 |
| Nohejlová, K | 2 |
| Ševčíková, M | 2 |
| Hrebíčková, I | 2 |
| Šlamberová, R | 4 |
| Smid, MC | 1 |
| Metz, TD | 1 |
| Gordon, AJ | 1 |
| Kapoor, A | 1 |
| Jackson, KS | 1 |
| Okunoye, GO | 1 |
| Dutton, P | 1 |
| Turner, JJ | 4 |
| Parrott, AC | 5 |
| Goodwin, J | 4 |
| Moore, DG | 5 |
| Fulton, S | 3 |
| Min, MO | 5 |
| Singer, LT | 5 |
| Kaizaki, A | 1 |
| Tanaka, S | 1 |
| Yoshida, T | 1 |
| Numazawa, S | 1 |
| Canales, JJ | 1 |
| Ferrer-Donato, A | 1 |
| Meyer, MR | 1 |
| Richter, LH | 1 |
| Maurer, HH | 1 |
| McDonnell-Dowling, K | 1 |
| Kelly, JP | 1 |
| Mercer, LD | 1 |
| Higgins, GC | 1 |
| Lau, CL | 1 |
| Lawrence, AJ | 1 |
| Beart, PM | 1 |
| Cho, KO | 1 |
| Rhee, GS | 3 |
| Kwack, SJ | 2 |
| Chung, SY | 1 |
| Kim, SY | 1 |
| Lipton, JW | 3 |
| Tolod, EG | 1 |
| Thompson, VB | 2 |
| Pei, L | 1 |
| Paumier, KL | 1 |
| Terpstra, BT | 1 |
| Lynch, KA | 1 |
| Collier, TJ | 1 |
| Sortwell, CE | 1 |
| Berman, S | 1 |
| O'Neill, J | 1 |
| Fears, S | 1 |
| Bartzokis, G | 1 |
| London, ED | 1 |
| Heiman, J | 1 |
| Chambers, JB | 1 |
| Benoit, SC | 1 |
| Buesing, WR | 1 |
| Norman, MK | 1 |
| Norman, AB | 1 |
| Skelton, MR | 3 |
| Schaefer, TL | 3 |
| Herring, NR | 2 |
| Grace, CE | 1 |
| Vorhees, CV | 4 |
| Williams, MT | 4 |
| Joya, X | 2 |
| Papaseit, E | 1 |
| Civit, E | 2 |
| Pellegrini, M | 3 |
| Vall, O | 4 |
| Garcia-Algar, O | 3 |
| Scaravelli, G | 2 |
| Pichini, S | 4 |
| Frederick, AL | 1 |
| Stanwood, GD | 1 |
| Chae, M | 1 |
| Jang, IS | 1 |
| Kim, K | 1 |
| Lee, JH | 1 |
| Lee, SY | 1 |
| Kim, M | 1 |
| Yang, J | 1 |
| Park, J | 1 |
| Lee, SH | 1 |
| Keating, E | 1 |
| Gonçalves, P | 1 |
| Campos, I | 1 |
| Costa, F | 1 |
| Martel, F | 1 |
| Macia, N | 1 |
| Camps, L | 2 |
| de Lapuente, J | 2 |
| Gonzalez-Linares, J | 2 |
| Borras, M | 2 |
| Rodamilans, M | 2 |
| Llobet, JM | 3 |
| Adori, C | 1 |
| Zelena, D | 1 |
| Tímár, J | 1 |
| Gyarmati, Z | 1 |
| Domokos, A | 1 |
| Sobor, M | 1 |
| Fürst, Z | 1 |
| Makara, G | 1 |
| Bagdy, G | 1 |
| Turner, JD | 1 |
| Goodwin, JE | 1 |
| Fulton, SE | 1 |
| Fox, HC | 1 |
| Braddick, FM | 1 |
| Axelsson, EL | 1 |
| Lynch, S | 1 |
| Ribeiro, H | 1 |
| Frostick, CJ | 1 |
| Biezonski, DK | 1 |
| Meyer, JS | 1 |
| Pujadas, M | 1 |
| Falcón, M | 2 |
| Luna, A | 2 |
| de la Torre, R | 1 |
| Valero, F | 1 |
| Rotolo, MC | 1 |
| Joya, J | 1 |
| García Algar, O | 1 |
| Eun, JW | 1 |
| Noh, JH | 1 |
| Jung, KH | 1 |
| Kim, JK | 1 |
| Bae, HJ | 1 |
| Xie, H | 1 |
| Ryu, JC | 1 |
| Ahn, YM | 1 |
| Park, WS | 1 |
| Lee, JY | 1 |
| Nam, SW | 1 |
| Teixido, E | 1 |
| Serret, J | 1 |
| Dzietko, M | 1 |
| Sifringer, M | 1 |
| Klaus, J | 1 |
| Endesfelder, S | 1 |
| Brait, D | 1 |
| Hansen, HH | 1 |
| Bendix, I | 1 |
| Felderhoff-Mueser, U | 1 |
| Simmat-Durand, L | 1 |
| Toutain, S | 1 |
| Vellut, N | 1 |
| Genest, L | 1 |
| Crenn-Hebert, C | 1 |
| Simonpoli, AM | 1 |
| Miossec, E | 1 |
| Lejeune, C | 1 |
| Flick, B | 1 |
| Boix, N | 1 |
| Almeida, B | 1 |
| Joglar, J | 1 |
| Klug, S | 1 |
| Pometlová, M | 1 |
| Schutová, B | 1 |
| Hrubá, L | 1 |
| Nová, E | 1 |
| Rokyta, R | 1 |
| Yamamotová, A | 1 |
| Won, L | 1 |
| Bubula, N | 1 |
| Heller, A | 1 |
| Kelly, PA | 1 |
| Ritchie, IM | 1 |
| Quate, L | 1 |
| McBean, DE | 1 |
| Olverman, HJ | 1 |
| Kuczkowski, KM | 1 |
| Koprich, JB | 1 |
| Campbell, NG | 1 |
| Morley-Fletcher, S | 1 |
| Puopolo, M | 1 |
| Gentili, S | 1 |
| Gerra, G | 1 |
| Macchia, T | 1 |
| Laviola, G | 1 |
| Hrometz, SL | 1 |
| Brown, AW | 1 |
| Nichols, DE | 1 |
| Sprague, JE | 1 |
| Bateman, DN | 2 |
| McElhatton, PR | 2 |
| Dickinson, D | 1 |
| Wren, C | 1 |
| Matthews, JN | 1 |
| O'Keeffe, M | 1 |
| Thomas, SH | 2 |
| Thomasius, R | 1 |
| Gouzoulis-Mayfrank, E | 1 |
| Karus, C | 1 |
| Wiedenmann, H | 1 |
| Hermle, L | 1 |
| Sack, PM | 1 |
| Zeichner, D | 1 |
| Küstner, U | 1 |
| Schindler, A | 1 |
| Krüger, A | 1 |
| Uhlmann, S | 1 |
| Petersen, KU | 1 |
| Zapletalova, P | 1 |
| Wartberg, L | 1 |
| Schütz, CG | 1 |
| Schulte-Markwort, M | 1 |
| Obrocki, J | 1 |
| Heinz, A | 1 |
| Schmoldt, A | 1 |
| Puig, C | 1 |
| Zuccaro, P | 1 |
| Marchei, E | 1 |
| Murillo, J | 1 |
| Pacifici, R | 1 |
| Rojas, R | 1 |
| Riascos, R | 1 |
| Vargas, D | 1 |
| Cuellar, H | 1 |
| Borne, J | 1 |
| Gudelsky, GA | 1 |
| Cerruti, C | 1 |
| Sheng, P | 1 |
| Ladenheim, B | 1 |
| Epstein, CJ | 1 |
| Cadet, JL | 1 |
| Kramer, K | 1 |
| Azmitia, EC | 2 |
| Whitaker-Azmitia, PM | 1 |
| Bronson, ME | 1 |
| Jiang, W | 1 |
| Clark, CR | 1 |
| DeRuiter, J | 1 |
| Broening, HW | 1 |
| Bacon, L | 1 |
| Slikker, W | 1 |
| Gu, XF | 1 |
| Colado, MI | 1 |
| O'Shea, E | 1 |
| Granados, R | 1 |
| Misra, A | 1 |
| Murray, TK | 1 |
| Green, AR | 1 |
| van Tonningen-van Driel, MM | 1 |
| Garbis-Berkvens, JM | 1 |
| Reuvers-Lodewijks, WE | 1 |
| Mortensen, OV | 1 |
| Kristensen, AS | 1 |
| Rudnick, G | 1 |
| Wiborg, O | 1 |
| Evans, C | 1 |
| Pughe, KR | 1 |
| Birnbach, DJ | 1 |
| Diaz, V | 1 |
| Wyckoff, MM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)[NCT03269110] | 2,578 participants (Anticipated) | Observational | 2017-07-01 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for n-methyl-3,4-methylenedioxyamphetamine and Pregnancy
| Article | Year |
|---|---|
Developmental neurotoxicity of MDMA. A systematic literature review summarized in a putative adverse outcome pathway.
Topics: Adverse Outcome Pathways; Animals; Brain; Female; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Ne | 2020 |
Stimulant Use in Pregnancy: An Under-recognized Epidemic Among Pregnant Women.
Topics: Alkaloids; Central Nervous System Stimulants; Cocaine; Female; Humans; Methamphetamine; N-Methyl-3,4 | 2019 |
MDMA and heightened cortisol: a neurohormonal perspective on the pregnancy outcomes of mothers used 'Ecstasy' during pregnancy.
Topics: Animals; Female; Fetal Development; Hallucinogens; Humans; Hydrocortisone; Hypothalamo-Hypophyseal S | 2014 |
Sources of variation in the design of preclinical studies assessing the effects of amphetamine-type stimulants in pregnancy and lactation.
Topics: Amphetamine; Amphetamines; Animals; Animals, Newborn; Central Nervous System Stimulants; Disease Mod | 2015 |
Abuse of amphetamines and structural abnormalities in the brain.
Topics: Abnormalities, Drug-Induced; Adult; Amphetamine-Related Disorders; Amphetamines; Animals; Attention | 2008 |
Drugs, biogenic amine targets and the developing brain.
Topics: Adult; Amphetamine-Related Disorders; Animals; Behavior; Biogenic Amines; Brain; Brain Chemistry; Ch | 2009 |
[AWMF-guideline: cocaine-, amphetamine-, ecstasy- and hallucinogen-related disorders].
Topics: Adult; Amphetamine-Related Disorders; Cocaine-Related Disorders; Comorbidity; Evidence-Based Medicin | 2004 |
Neuroimaging in drug and substance abuse part I: cocaine, cannabis, and ecstasy.
Topics: Atrophy; Central Nervous System Diseases; Cocaine-Related Disorders; Female; Hallucinogens; Humans; | 2005 |
Developmental effects of 3,4-methylenedioxymethamphetamine: a review.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Female; Hallucinogens; Learning; Memory; N-Methyl-3,4 | 2008 |
Surviving fulminant hepatic failure.
Topics: Acute Disease; Adolescent; Anuria; Critical Care; Diagnosis, Differential; Female; Graft Rejection; | 2002 |
1 trial available for n-methyl-3,4-methylenedioxyamphetamine and Pregnancy
| Article | Year |
|---|---|
[Pregnancy outcome after ecstasy use; 43 cases followed by the Teratology Information Service of the National Institute for Public Health and Environment (RIVM)].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adolescent; Adult; Female; Follow-Up Studies; Ha | 1999 |
53 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Pregnancy
| Article | Year |
|---|---|
Psychedelic Drug Legislative Reform and Legalization in the US.
Topics: Adolescent; Aged; Educational Status; Female; Hallucinogens; Humans; Mescaline; N-Methyl-3,4-methyle | 2023 |
Psychedelic Drug Legislative Reform and Legalization in the US.
Topics: Adolescent; Aged; Educational Status; Female; Hallucinogens; Humans; Mescaline; N-Methyl-3,4-methyle | 2023 |
Psychedelic Drug Legislative Reform and Legalization in the US.
Topics: Adolescent; Aged; Educational Status; Female; Hallucinogens; Humans; Mescaline; N-Methyl-3,4-methyle | 2023 |
Psychedelic Drug Legislative Reform and Legalization in the US.
Topics: Adolescent; Aged; Educational Status; Female; Hallucinogens; Humans; Mescaline; N-Methyl-3,4-methyle | 2023 |
In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice.
Topics: Age Factors; Animals; Brain; Calcium-Binding Proteins; Dexamethasone; Disease Models, Animal; Diseas | 2021 |
Sex differences in the strategies of spatial learning in prenatally-exposed rats treated with various drugs in adulthood.
Topics: Animals; Cocaine; Cognition; Dronabinol; Female; Male; Methamphetamine; Morphine; N-Methyl-3,4-methy | 2017 |
Seizures presenting in pregnancy: eclampsia or something else?
Topics: Adrenergic Uptake Inhibitors; Diagnosis, Differential; Eclampsia; Female; Humans; N-Methyl-3,4-methy | 2013 |
Acute myocardial infarction in pregnancy following unlicensed use of methylenedioxymethamphetamine ('Ecstasy').
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic Uptake Inhibitors; Adult; Aspirin; Bisoprolol; Ch | 2013 |
Psychiatric profiles of mothers who take Ecstasy/MDMA during pregnancy: reduced depression 1 year after giving birth and quitting Ecstasy.
Topics: Adult; Case-Control Studies; Depression; Drug Users; Female; Health Status; Humans; Illicit Drugs; M | 2014 |
Maternal MDMA administration in mice leads to neonatal growth delay.
Topics: Animals; Behavior, Animal; Body Weight; Female; Gestational Age; Growth and Development; Illicit Dru | 2014 |
Prenatal exposure to alcohol and 3,4-methylenedioxymethamphetamine (ecstasy) alters adult hippocampal neurogenesis and causes enduring memory deficits.
Topics: Animals; Behavior, Animal; Doublecortin Protein; Ethanol; Exploratory Behavior; Female; Hippocampus; | 2014 |
Methylenedioxy designer drugs: mass spectrometric characterization of their glutathione conjugates by means of liquid chromatography-high-resolution mass spectrometry/mass spectrometry and studies on their glutathionyl transferase inhibition potency.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Deoxyepinephrine; Dinitrochlor | 2014 |
Developmental outcomes of 3,4-methylenedioxymethamphetamine (ecstasy)-exposed infants in the UK.
Topics: Adult; Age Factors; Child Development; Developmental Disabilities; Female; Hallucinogens; Humans; In | 2015 |
How various drugs affect anxiety-related behavior in male and female rats prenatally exposed to methamphetamine.
Topics: Analgesics; Analysis of Variance; Animals; Anxiety; Central Nervous System Stimulants; Estrous Cycle | 2016 |
MDMA-induced neurotoxicity of serotonin neurons involves autophagy and rilmenidine is protective against its pathobiology.
Topics: Adrenergic alpha-Agonists; Animals; Autophagy; Cell Survival; Cells, Cultured; Dose-Response Relatio | 2017 |
Developmental exposure to 3,4-methylenedioxymethamphetamine results in downregulation of neurogenesis in the adult mouse hippocampus.
Topics: Animals; Antimetabolites; Astrocytes; Birth Weight; Bromodeoxyuridine; Cell Count; Cell Proliferatio | 2008 |
3,4-Methylenedioxy-N-methamphetamine (ecstasy) promotes the survival of fetal dopamine neurons in culture.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Dopamine; Dopamine | 2008 |
Long-term behavioral consequences of prenatal MDMA exposure.
Topics: Analysis of Variance; Animals; Association Learning; Attention; Behavior, Animal; Cocaine; Critical | 2009 |
Comparison of the developmental effects of 5-methoxy-N,N-diisopropyltryptamine (Foxy) to (+/-)-3,4-methylenedioxymethamphetamine (ecstasy) in rats.
Topics: Aging; Animals; Anxiety; Body Weight; Cues; Female; Hallucinogens; Learning; Lighting; Maze Learning | 2009 |
Unsuspected exposure to cocaine in preschool children from a Mediterranean city detected by hair analysis.
Topics: Amphetamines; Cannabis; Child; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; | 2009 |
ATG5 expression induced by MDMA (ecstasy), interferes with neuronal differentiation of neuroblastoma cells.
Topics: Animals; Autophagy; Autophagy-Related Protein 5; Cell Differentiation; Embryo Culture Techniques; Fe | 2009 |
Folic acid uptake by the human syncytiotrophoblast: interference by pharmacotherapy, drugs of abuse and pathological conditions.
Topics: Amphetamine; Antihypertensive Agents; Atenolol; Biological Transport; Cell Survival; Cells, Cultured | 2009 |
Chronic exposure to MDMA (ecstasy) increases DNA damage in sperm and alters testes histopathology in male rats.
Topics: Animals; DNA Damage; Drinking; Epididymis; Female; Fertility; Follicle Stimulating Hormone; Luteiniz | 2009 |
Intermittent prenatal MDMA exposure alters physiological but not mood related parameters in adult rat offspring.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Behavior, Animal; Blood Glucose; Body Weight; Corpus | 2010 |
During pregnancy, recreational drug-using women stop taking ecstasy (3,4-methylenedioxy-N-methylamphetamine) and reduce alcohol consumption, but continue to smoke tobacco and cannabis: initial findings from the Development and Infancy Study.
Topics: Adult; Alcohol Drinking; Female; Hallucinogens; Humans; Illicit Drugs; Longitudinal Studies; Marijua | 2010 |
Effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin transporter and vesicular monoamine transporter 2 protein and gene expression in rats: implications for MDMA neurotoxicity.
Topics: 5,7-Dihydroxytryptamine; Animals; Area Under Curve; Benzylamines; Brain; Central Nervous System Stim | 2010 |
Gas chromatography-mass spectrometry assay for the simultaneous quantification of drugs of abuse in human placenta at 12th week of gestation.
Topics: Abortion, Induced; Amphetamines; Cocaine; Cotinine; Dronabinol; Female; Forensic Toxicology; Ganglio | 2010 |
Exposure to psychoactive substances in women who request voluntary termination of pregnancy assessed by serum and hair testing.
Topics: Abortion, Induced; Adolescent; Adult; Alcohol Drinking; Cannabinoids; Cocaine; Cohort Studies; Contr | 2010 |
Identification of post-generation effect of 3,4-methylenedioxymethamphetamine on the mouse brain by large-scale gene expression analysis.
Topics: Animals; Brain; Female; Gene Expression Profiling; Gene Expression Regulation; Male; Mice; Mice, Inb | 2010 |
MDMA (ecstasy) delays pubertal development and alters sperm quality after developmental exposure in the rat.
Topics: Animals; Female; Fertility; Hallucinogens; Hypothalamo-Hypophyseal System; Lactation; Male; N-Methyl | 2010 |
Neurotoxic effects of MDMA (ecstasy) on the developing rodent brain.
Topics: Adolescent; Animals; Animals, Newborn; Brain; Brain-Derived Neurotrophic Factor; Female; Humans; Mal | 2010 |
[Maternal and obstetrical data in a retrospective cohort of 170 newborns from polydrug using mothers, in the Paris area, 1999-2008].
Topics: Abortion, Induced; Cocaine-Related Disorders; Cohort Studies; Ethanol; Female; Heroin Dependence; Hu | 2010 |
Effects of MDMA (ecstasy) and two of its metabolites on rat embryos in vitro.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Deoxyepinephrine; Embryo, Mammalian; Embryonic Development; | 2012 |
One-year outcomes of prenatal exposure to MDMA and other recreational drugs.
Topics: Cognition; Developmental Disabilities; Dose-Response Relationship, Drug; Female; Hallucinogens; Huma | 2012 |
Do prenatally methamphetamine-exposed adult male rats display general predisposition to drug abuse in the conditioned place preference test?
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Psychologic | 2012 |
Behavioral and antinociceptive effects of different psychostimulant drugs in prenatally methamphetamine-exposed rats.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Female; Male; Me | 2012 |
Fetal exposure to (+/-)-methylenedioxymethamphetamine in utero enhances the development and metabolism of serotonergic neurons in three-dimensional reaggregate tissue culture.
Topics: Animals; Cell Count; Cells, Cultured; Dopamine; Female; Fetus; Litter Size; Mice; Mice, Inbred C57BL | 2002 |
Functional consequences of perinatal exposure to 3,4-methylenedioxymethamphetamine in rat brain.
Topics: Adrenergic Uptake Inhibitors; Animals; Animals, Newborn; Binding, Competitive; Brain; Female; Glucos | 2002 |
Diagnostic tattoo in a parturient with 'ecstasy' use.
Topics: Adolescent; Female; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Pregnancy; Pregna | 2003 |
Neonatal 3,4-methylenedioxymethamphetamine (ecstasy) alters dopamine and serotonin neurochemistry and increases brain-derived neurotrophic factor in the forebrain and brainstem of the rat.
Topics: Animals; Animals, Newborn; Brain Chemistry; Brain Stem; Brain-Derived Neurotrophic Factor; Chromatog | 2003 |
Prenatal stress affects 3,4-methylenedioxymethamphetamine pharmacokinetics and drug-induced motor alterations in adolescent female rats.
Topics: Animals; Female; Hallucinogens; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Pregnancy; P | 2004 |
3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated production of hydrogen peroxide in an in vitro model: the role of dopamine, the serotonin-reuptake transporter, and monoamine oxidase-B.
Topics: Cell Line, Tumor; Cell Survival; Choriocarcinoma; Dopamine; Drug Interactions; Female; Fluoxetine; H | 2004 |
A case control study to examine the pharmacological factors underlying ventricular septal defects in the North of England.
Topics: Adolescent; Adult; Amphetamines; Birth Weight; Case-Control Studies; Cohort Studies; Drug-Related Si | 2004 |
Assessment of exposure to opiates and cocaine during pregnancy in a Mediterranean city: preliminary results of the "Meconium Project".
Topics: Abortion, Induced; Adult; Arecoline; Body Height; Cholinergic Agonists; Cocaine; Dopamine Uptake Inh | 2005 |
Developmental effects of +/-3,4-methylenedioxymethamphetamine on spatial versus path integration learning: effects of dose distribution.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Dose-Re | 2007 |
Short- and long-term effects of (+)-methamphetamine and (+/-)-3,4-methylenedioxymethamphetamine on monoamine and corticosterone levels in the neonatal rat following multiple days of treatment.
Topics: Adrenergic Uptake Inhibitors; Animals; Animals, Newborn; Biogenic Monoamines; Body Weight; Corticost | 2008 |
Involvement of oxidative and L-arginine-NO pathways in the neurotoxicity of drugs of abuse in vitro.
Topics: Adenosine Diphosphate Ribose; Animals; Arginine; Brain; Cell Death; Cells, Cultured; Dopamine; Dopam | 1995 |
In vitro release of [3H]5-hydroxytryptamine from fetal and maternal brain by drugs of abuse.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Brain Chemistry; Cocaine; Designer Drugs; Female; Fen | 1994 |
Effects of designer drugs on the chicken embryo and 1-day-old chicken.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Animals, Newborn; Body Weight; Chick Embryo; Chickens; Desig | 1994 |
Age modulates the long-term but not the acute effects of the serotonergic neurotoxicant 3,4-methylenedioxymethamphetamine.
Topics: Age Factors; Animals; Body Temperature; Brain; Dopamine; Dose-Response Relationship, Drug; Female; N | 1994 |
Integrative transporter-mediated release from cytoplasmic and vesicular 5-hydroxytryptamine stores in cultured neurons.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Stem; Carrier Proteins; Cells, Cultured; Clorgyline; F | 1993 |
A study of the neurotoxic effect of MDMA ('ecstasy') on 5-HT neurones in the brains of mothers and neonates following administration of the drug during pregnancy.
Topics: Animals; Body Temperature; Body Weight; Brain; Dopamine; Female; Hydroxyindoleacetic Acid; Lipid Per | 1997 |
Molecular cloning, expression and characterization of a bovine serotonin transporter.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cattle; Citalopram; Cloning, Molecular; Desipramine; | 1999 |
Congenital anomalies after prenatal ecstasy exposure.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Female; Hallucinogens; Humans; Infant, Newborn; Male | 1999 |
Interactions in anesthesia: anesthetic management of the drug abusing parturient.
Topics: Alcoholism; Amphetamine-Related Disorders; Anesthesia, Obstetrical; Cocaine-Related Disorders; Femal | 2001 |
Ecstasy and pregnancy: warn against ecstasy use.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adrenergic Uptake Inhibitors; Female; Humans; N- | 2002 |