n-methyl-3,4-methylenedioxyamphetamine has been researched along with Mydriasis in 4 studies
N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.
Mydriasis: Dilation of pupils to greater than 6 mm combined with failure of the pupils to constrict when stimulated with light. This condition may occur due to injury of the pupillary fibers in the oculomotor nerve, in acute angle-closure glaucoma, and in ADIE SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Clonidine did not significantly reduce the mydriatic effects of MDMA, although it produced miosis when administered alone." | 4.88 | Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex. ( Hysek, CM; Liechti, ME, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lemoine, C | 1 |
| Bréhin, C | 1 |
| Micheau, P | 1 |
| Lavit, M | 1 |
| Claudet, I | 1 |
| Fogel, S | 1 |
| Lesage, F | 1 |
| Cheron, G | 1 |
| Hysek, CM | 1 |
| Liechti, ME | 1 |
| Melian, AM | 1 |
| Burillo-Putze, G | 1 |
| Campo, CG | 1 |
| Padron, AG | 1 |
| Ramos, CO | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacological Interaction Between Duloxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy): Pharmacodynamics (PD) and Pharmacokinetics (PK)[NCT00990067] | Phase 1 | 16 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| Pharmacological Interaction Between Reboxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy): Pharmacological Effects and Pharmacokinetics[NCT00886886] | Phase 1 | 16 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
| Pharmacological Interaction Between Clonidine and 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy)[NCT01136278] | Phase 1 | 16 participants (Actual) | Interventional | 2010-07-31 | Completed | ||
| Interactive Effects of Doxazosin and 3,4-Methylenedioxymethamphetamine (MDMA) in Healthy Subjects[NCT01386177] | Phase 1 | 16 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| "Effects of Carvedilol on the Cardiovascular and Subjective Response to MDMA (3,4-Methylenedioxymethamphetamine, Ecstasy)"[NCT01270672] | 16 participants (Actual) | Interventional | 2011-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for n-methyl-3,4-methylenedioxyamphetamine and Mydriasis
| Article | Year |
|---|---|
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affe | 2012 |
3 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Mydriasis
| Article | Year |
|---|---|
An unusual route of non-intentional intoxication by ecstasy in a toddler.
Topics: Child; Child, Preschool; Female; Fever; Humans; Hypertension; Mydriasis; N-Methyl-3,4-methylenedioxy | 2023 |
[Accidental amphetamine poisoning in an 11-month-old boy].
Topics: Accidents, Home; Akathisia, Drug-Induced; Amphetamine; Humans; Infant; Male; Mydriasis; N-Methyl-3,4 | 2016 |
Accidental ecstasy poisoning in a toddler.
Topics: Accidents, Home; Benzodiazepines; Cardiac Complexes, Premature; Combined Modality Therapy; Fever; Hu | 2004 |