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n-methyl-3,4-methylenedioxyamphetamine and Muscle Contraction

n-methyl-3,4-methylenedioxyamphetamine has been researched along with Muscle Contraction in 6 studies

N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Consequently, the malignant hyperthermia status should not affect the calcium sensitivity of the contractile apparatus."1.383,4-Methylenedioxymethamphetamine (Ecstasy) increases the sensitivity of the contractile apparatus to calcium ions in both malignant hyperthermia-susceptible and normal skeletal muscle fibres. ( Gerbershagen, MU; Graf, BM; Missler, G; Schütte, JK; Starosse, A; Wappler, F; Zink, W, 2012)
" The left-shift of the dose-response curve induced by MDMA was greater in normal than in MHS muscle."1.333,4-Methylenedioxymethamphetamine (ecstasy) activates skeletal muscle nicotinic acetylcholine receptors. ( Alt, A; Bufler, J; Heffron, JJ; Jurkat-Rott, K; Klingler, W; Lehmann-Horn, F; O'sullivan, G; Schlesinger, F, 2005)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dawson, P1
Opacka-Juffry, J1
Moffatt, JD1
Daniju, Y1
Dutta, N1
Ramsey, J1
Davidson, C1
Gerbershagen, MU1
Missler, G1
Schütte, JK1
Starosse, A1
Graf, BM1
Wappler, F1
Zink, W1
Klingler, W1
Heffron, JJ1
Jurkat-Rott, K1
O'sullivan, G1
Alt, A1
Schlesinger, F1
Bufler, J1
Lehmann-Horn, F1
Bexis, S1
Docherty, JR2
Denborough, MA1
Hopkinson, KC1
Rajamani, K1
Leong, S1
Lavelle, A1

Other Studies

6 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Muscle Contraction

ArticleYear
The effects of benzofury (5-APB) on the dopamine transporter and 5-HT2-dependent vasoconstriction in the rat.
    Progress in neuro-psychopharmacology & biological psychiatry, 2014, Jan-03, Volume: 48

    Topics: Animals; Aorta; Benzofurans; Brain; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins;

2014
3,4-Methylenedioxymethamphetamine (Ecstasy) increases the sensitivity of the contractile apparatus to calcium ions in both malignant hyperthermia-susceptible and normal skeletal muscle fibres.
    European journal of anaesthesiology, 2012, Volume: 29, Issue:1

    Topics: Animals; Calcium Signaling; Dose-Response Relationship, Drug; Malignant Hyperthermia; Muscle Contrac

2012
3,4-Methylenedioxymethamphetamine (ecstasy) activates skeletal muscle nicotinic acetylcholine receptors.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Malignant Hyperthermia;

2005
Effects of MDMA, MDA and MDEA on blood pressure, heart rate, locomotor activity and body temperature in the rat involve alpha-adrenoceptors.
    British journal of pharmacology, 2006, Volume: 147, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Aorta; Blood Pressure; Body Temperature; Heart Rate; Imidazo

2006
Dantrolene and "ecstasy".
    The Medical journal of Australia, 1997, Feb-03, Volume: 166, Issue:3

    Topics: Calcium; Dantrolene; Hallucinogens; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Cont

1997
Prejunctional actions of methylenedioxymethamphetamine in vas deferens from wild-type and alpha(2A/D)-adrenoceptor knockout mice.
    European journal of pharmacology, 2001, Jul-06, Volume: 423, Issue:2-3

    Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Desipramine; Do

2001