n-methyl-3,4-methylenedioxyamphetamine has been researched along with Memory Disorders in 100 studies
N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.
Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketanserin caused an increase in AEA concentrations, 180 min after administration." | 2.87 | Peripheral endocannabinoid concentrations are not associated with verbal memory impairment during MDMA intoxication. ( de la Torre, R; Farre, M; Haijen, E; Kuypers, KPC; Olesti, E; Pastor, A; Pizarro, N; Ramaekers, JG, 2018) |
| "Ecstasy use is commonly linked with memory deficits in abstinent ecstasy users." | 2.78 | Inhibition of MDMA-induced increase in cortisol does not prevent acute impairment of verbal memory. ( de la Torre, R; Farre, M; Kuypers, KP; Pujadas, M; Ramaekers, JG, 2013) |
| " Thus, the current state of research does not allow for the conclusion that long-term use of MDMA affects decision-making behavior in general." | 2.55 | Decision-making in chronic ecstasy users: a systematic review. ( Betzler, F; Romanczuk-Seiferth, N; Viohl, L, 2017) |
| "The chronic intake of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") bears a strong risk for sustained declarative memory impairments." | 1.91 | The functional connectome of 3,4-methyldioxymethamphetamine-related declarative memory impairments. ( Baumgartner, MR; Beste, C; Cole, DM; Coray, RC; Haugg, A; Quednow, BB; Seifritz, E; Steuer, AE; Stock, AK; Zimmermann, J, 2023) |
| "In turn, new hypotheses suggest that Alzheimer's disease (AD) may be promoted by neural stressors." | 1.51 | Effects of MDMA on neuroplasticity, amyloid burden and phospho-tau expression in APPswe/PS1dE9 mice. ( Abad, S; Camarasa, J; Camins, A; Escubedo, E; Folch, J; López-Arnau, R; Pubill, D; Ramon-Duaso, C, 2019) |
| "Nicotine or MDMA treatment reduced memory function and altered hippocampal structure." | 1.43 | Neural and behavioural changes in male periadolescent mice after prolonged nicotine-MDMA treatment. ( Adeniyi, PA; Bankole, OO; Ishola, AO; Laoye, BJ; Ogundele, OM; Olatunji, BP; Shallie, PD, 2016) |
| "Pre-treatment with memantine did not prevent MDMA-induced memory impairment in these two tasks." | 1.40 | Memory and mood during MDMA intoxication, with and without memantine pretreatment. ( de la Torre, R; de Sousa Fernandes Perna, EB; Farre, M; Heckman, P; Kuypers, KP; Ramaekers, JG; Theunissen, EL, 2014) |
| "We conclude that memory deficits of MDMA users arise from combined fronto-parieto-mediotemporal dysfunction." | 1.39 | Verbal memory deficits are correlated with prefrontal hypometabolism in (18)FDG PET of recreational MDMA users. ( Biersack, HJ; Bosch, OG; Jessen, F; Joe, A; Kühn, KU; Maier, W; Quednow, BB; Seifritz, E; Wagner, M, 2013) |
| "A rat model for learning and memory deficits has not been established, although some cognitive deficits have been reported." | 1.33 | 3,4-Methylenedioxymethamphetamine in adult rats produces deficits in path integration and spatial reference memory. ( Able, JA; Gudelsky, GA; Vorhees, CV; Williams, MT, 2006) |
| "Additionally, users that met DSM-IV substance use disorder criteria for lifetime MDMA abuse or dependence exhibited a number of additional deficits relative to those who did not meet these criteria." | 1.32 | Neurocognitive function in users of MDMA: the importance of clinically significant patterns of use. ( Hanson, KL; Luciana, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (3.00) | 18.2507 |
| 2000's | 53 (53.00) | 29.6817 |
| 2010's | 40 (40.00) | 24.3611 |
| 2020's | 4 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kloft, L | 1 |
| Otgaar, H | 1 |
| Blokland, A | 1 |
| Toennes, SW | 1 |
| Ramaekers, JG | 9 |
| Levent, A | 1 |
| Davelaar, EJ | 1 |
| Coray, RC | 1 |
| Zimmermann, J | 1 |
| Haugg, A | 1 |
| Baumgartner, MR | 2 |
| Steuer, AE | 1 |
| Seifritz, E | 3 |
| Stock, AK | 1 |
| Beste, C | 1 |
| Cole, DM | 1 |
| Quednow, BB | 4 |
| Taghizadeh, G | 1 |
| Mehdizadeh, H | 1 |
| Lavasani, H | 1 |
| Hosseinzadeh Ardakani, Y | 1 |
| Foroumadi, A | 1 |
| Halvaei Khankahdani, Z | 1 |
| Moshtagh, A | 1 |
| Pourahmad, J | 1 |
| Sharifzadeh, M | 1 |
| Rouini, MR | 1 |
| Gharebaghi, A | 1 |
| Amiri, I | 1 |
| Salehi, I | 1 |
| Shahidi, S | 1 |
| Komaki, A | 1 |
| Mehdizadeh, M | 1 |
| Moravej, FG | 1 |
| Asl, SS | 1 |
| Cadoni, C | 1 |
| Pisanu, A | 1 |
| Simola, N | 1 |
| Frau, L | 1 |
| Porceddu, PF | 1 |
| Corongiu, S | 1 |
| Dessì, C | 1 |
| Sil, A | 1 |
| Plumitallo, A | 1 |
| Wardas, J | 1 |
| Di Chiara, G | 1 |
| Parrott, AC | 12 |
| Downey, LA | 2 |
| Roberts, CA | 1 |
| Montgomery, C | 11 |
| Bruno, R | 2 |
| Fox, HC | 3 |
| Wunderli, MD | 1 |
| Vonmoos, M | 1 |
| Fürst, M | 1 |
| Schädelin, K | 1 |
| Kraemer, T | 1 |
| García-Pardo, MP | 1 |
| De la Rubia Ortí, JE | 1 |
| Aguilar Calpe, MA | 1 |
| Haijen, E | 1 |
| Farre, M | 4 |
| de la Torre, R | 4 |
| Pastor, A | 1 |
| Olesti, E | 1 |
| Pizarro, N | 1 |
| Kuypers, KPC | 1 |
| Platt, B | 1 |
| O'Driscoll, C | 1 |
| Curran, VH | 1 |
| Rendell, PG | 2 |
| Kamboj, SK | 1 |
| Abad, S | 3 |
| Ramon-Duaso, C | 1 |
| López-Arnau, R | 1 |
| Folch, J | 1 |
| Pubill, D | 3 |
| Camarasa, J | 3 |
| Camins, A | 3 |
| Escubedo, E | 3 |
| Ros-Simó, C | 1 |
| Moscoso-Castro, M | 1 |
| Ruiz-Medina, J | 1 |
| Ros, J | 1 |
| Valverde, O | 1 |
| Bosch, OG | 1 |
| Wagner, M | 2 |
| Jessen, F | 2 |
| Kühn, KU | 2 |
| Joe, A | 1 |
| Maier, W | 2 |
| Biersack, HJ | 1 |
| Taurah, L | 1 |
| Chandler, C | 1 |
| Sanders, G | 1 |
| Fole, A | 1 |
| del Olmo, N | 1 |
| Pallàs, M | 1 |
| Junyent, F | 1 |
| Fisk, JE | 11 |
| Gallagher, DT | 1 |
| Hadjiefthyvoulou, F | 3 |
| Canales, JJ | 1 |
| Ferrer-Donato, A | 1 |
| Doblin, R | 1 |
| Greer, G | 1 |
| Holland, J | 1 |
| Jerome, L | 1 |
| Mithoefer, MC | 1 |
| Sessa, B | 1 |
| Smithies, V | 1 |
| Broadbear, J | 1 |
| Verdejo-Garcia, A | 1 |
| Conduit, R | 1 |
| de Sousa Fernandes Perna, EB | 2 |
| Theunissen, EL | 3 |
| Kuypers, KP | 6 |
| Heckman, P | 1 |
| Macaskill, AC | 1 |
| Harrow, CC | 1 |
| Harper, DN | 2 |
| Sands, H | 1 |
| Jones, L | 1 |
| Clow, A | 1 |
| Evans, P | 1 |
| Stalder, T | 1 |
| Adeniyi, PA | 1 |
| Ishola, AO | 1 |
| Laoye, BJ | 1 |
| Olatunji, BP | 1 |
| Bankole, OO | 1 |
| Shallie, PD | 1 |
| Ogundele, OM | 1 |
| van Wel, JH | 2 |
| Linssen, A | 1 |
| Sambeth, A | 1 |
| Schultz, BG | 1 |
| Betzler, F | 1 |
| Viohl, L | 1 |
| Romanczuk-Seiferth, N | 1 |
| Wingen, M | 2 |
| Heinecke, A | 2 |
| Formisano, E | 2 |
| Rogers, G | 1 |
| Elston, J | 1 |
| Garside, R | 1 |
| Roome, C | 1 |
| Taylor, R | 1 |
| Younger, P | 1 |
| Zawada, A | 1 |
| Somerville, M | 1 |
| Pompili, M | 1 |
| Lester, D | 1 |
| Girardi, P | 1 |
| Tatarelli, R | 1 |
| Roberts, GM | 1 |
| Nestor, L | 1 |
| Garavan, H | 1 |
| Schilt, T | 3 |
| Koeter, MW | 1 |
| Smal, JP | 1 |
| Gouwetor, MN | 1 |
| van den Brink, W | 4 |
| Schmand, B | 4 |
| Nawata, Y | 1 |
| Hiranita, T | 1 |
| Yamamoto, T | 1 |
| Murphy, PN | 4 |
| Wareing, M | 5 |
| Bridges, N | 2 |
| Blagrove, M | 1 |
| Seddon, J | 1 |
| George, S | 1 |
| Stickgold, R | 1 |
| Walker, MP | 1 |
| Jones, KA | 1 |
| Morgan, MJ | 3 |
| Foëx, BA | 1 |
| Subramanian, G | 1 |
| Butler, JM | 1 |
| Adamaszek, M | 1 |
| Khaw, AV | 1 |
| Buck, U | 1 |
| Andresen, B | 1 |
| Thomasius, R | 1 |
| Schenk, S | 1 |
| Do, J | 1 |
| van Holst, RJ | 1 |
| Bosker, WM | 1 |
| Bakker, K | 1 |
| Weinborn, M | 1 |
| Woods, SP | 1 |
| Nulsen, C | 1 |
| Park, K | 1 |
| Ryland, I | 1 |
| Hilton, J | 1 |
| Wagner, D | 1 |
| Becker, B | 1 |
| Koester, P | 1 |
| Gouzoulis-Mayfrank, E | 6 |
| Daumann, J | 6 |
| Pujadas, M | 1 |
| McLean, A | 1 |
| Turner, JJ | 1 |
| Rogers, R | 1 |
| Sahakian, BJ | 1 |
| Buchanan, T | 2 |
| Scholey, AB | 2 |
| Heffernan, T | 1 |
| Ling, J | 2 |
| Rodgers, J | 2 |
| Simon, NG | 1 |
| Mattick, RP | 1 |
| Verbaten, MN | 1 |
| Fox, H | 1 |
| Milani, RM | 1 |
| Thimm, B | 2 |
| Rezk, M | 2 |
| Hensen, G | 2 |
| Jovanovski, D | 1 |
| Zakzanis, KK | 3 |
| Cowan, RL | 1 |
| Lyoo, IK | 1 |
| Sung, SM | 1 |
| Ahn, KH | 1 |
| Kim, MJ | 1 |
| Hwang, J | 1 |
| Haga, E | 1 |
| Vimal, RL | 1 |
| Lukas, SE | 1 |
| Renshaw, PF | 1 |
| Heffernan, TM | 1 |
| Hanson, KL | 1 |
| Luciana, M | 1 |
| Murphy, P | 2 |
| Fischermann, T | 2 |
| Heekeren, K | 1 |
| Henke, K | 1 |
| Thron, A | 1 |
| Soar, K | 1 |
| Verdejo-García, AJ | 1 |
| López-Torrecillas, F | 1 |
| Aguilar de Arcos, F | 1 |
| Pérez-García, M | 1 |
| Piper, BJ | 1 |
| Meyer, JS | 1 |
| Yip, JT | 1 |
| Lee, TM | 1 |
| Newcombe, R | 1 |
| Young, JM | 1 |
| McGregor, IS | 2 |
| Mallet, PE | 2 |
| Cybulska, B | 1 |
| Dafters, RI | 1 |
| Able, JA | 1 |
| Gudelsky, GA | 1 |
| Vorhees, CV | 1 |
| Williams, MT | 1 |
| Lamers, CT | 1 |
| Bechara, A | 1 |
| Rizzo, M | 1 |
| Campbell, Z | 1 |
| Daum, I | 1 |
| Ward, J | 1 |
| Hall, K | 1 |
| Haslam, C | 1 |
| Golding, JF | 1 |
| Groome, DH | 1 |
| Rycroft, N | 1 |
| Denton, Z | 1 |
| de Win, MM | 1 |
| Koeter, M | 1 |
| Jager, G | 1 |
| Korf, DJ | 1 |
| Hoshi, R | 1 |
| Mullins, K | 1 |
| Boundy, C | 1 |
| Brignell, C | 1 |
| Piccini, P | 1 |
| Curran, HV | 1 |
| Gray, TJ | 1 |
| Henry, JD | 1 |
| Tolan, A | 1 |
| Laws, KR | 1 |
| Kokkalis, J | 1 |
| de Sola Llopis, S | 1 |
| Miguelez-Pan, M | 1 |
| Peña-Casanova, J | 1 |
| Poudevida, S | 1 |
| Pacifici, R | 1 |
| Böhm, P | 1 |
| Abanades, S | 1 |
| Verdejo García, A | 1 |
| Langohr, K | 1 |
| Zuccaro, P | 1 |
| Bedi, G | 1 |
| Redman, J | 1 |
| von Wilmsdorff, M | 1 |
| Gastpar, M | 1 |
| Lasky, J | 1 |
| McGuire, P | 1 |
| Reneman, L | 2 |
| Booij, J | 2 |
| Gunning, B | 1 |
| Taffe, MA | 1 |
| Weed, MR | 1 |
| Davis, S | 1 |
| Huitrón-Resendiz, S | 1 |
| Schroeder, R | 1 |
| Parsons, LH | 1 |
| Henriksen, SJ | 1 |
| Gold, LH | 1 |
| Young, DA | 1 |
| Lavalaye, J | 1 |
| de Wolff, FA | 1 |
| den Heeten, GJ | 1 |
| McCann, UD | 1 |
| Ricaurte, GA | 1 |
| Molliver, ME | 1 |
| Morley, KC | 1 |
| Gallate, JE | 1 |
| Hunt, GE | 1 |
| McFie, L | 1 |
| Fleetwood, H | 1 |
| Robinson, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of MDMA on Prefrontal and Amygdala Activation in Posttraumatic Stress Disorder[NCT03752918] | Phase 1 | 20 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| Stimulation of Parieto-hippocampal Connectivity in Patients With Major Depressive Disorder[NCT04081519] | 53 participants (Actual) | Interventional | 2016-08-02 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 reviews available for n-methyl-3,4-methylenedioxyamphetamine and Memory Disorders
| Article | Year |
|---|---|
Recreational 3,4-methylenedioxymethamphetamine or 'ecstasy': Current perspective and future research prospects.
Topics: Biomedical Research; Cognitive Dysfunction; Fetal Development; Humans; Illicit Drugs; Memory Disorde | 2017 |
Differential effects of MDMA and cocaine on inhibitory avoidance and object recognition tests in rodents.
Topics: Adrenergic Uptake Inhibitors; Animals; Avoidance Learning; Behavior, Animal; Cocaine; Dopamine Uptak | 2017 |
The effects of licit and illicit recreational drugs on prospective memory: a meta-analytic review.
Topics: Alcohol Drinking; Cannabis; Hallucinogens; Humans; Illicit Drugs; Memory Disorders; Memory, Episodic | 2019 |
Human psychobiology of MDMA or 'Ecstasy': an overview of 25 years of empirical research.
Topics: Animals; Apoptosis; Empirical Research; Hallucinogens; Humans; Illicit Drugs; Memory Disorders; N-Me | 2013 |
Verbal Memory Impairment in Polydrug Ecstasy Users: A Clinical Perspective.
Topics: Adolescent; Adult; Case-Control Studies; Controlled Clinical Trials as Topic; Female; Humans; Male; | 2016 |
Decision-making in chronic ecstasy users: a systematic review.
Topics: Animals; Cognition Disorders; Decision Making; Humans; Memory Disorders; N-Methyl-3,4-methylenedioxy | 2017 |
The harmful health effects of recreational ecstasy: a systematic review of observational evidence.
Topics: Amphetamine-Related Disorders; Cognition; Databases, Bibliographic; Hallucinogens; Humans; Illicit D | 2009 |
Executive working memory deficits in abstinent ecstasy/MDMA users: a critical review.
Topics: Executive Function; Hallucinogens; Humans; Memory Disorders; Memory, Short-Term; N-Methyl-3,4-methyl | 2009 |
Drug-related decrease in neuropsychological functions of abstinent drug users.
Topics: Alcoholism; Amphetamine-Related Disorders; Cannabis; Central Nervous System Stimulants; Cocaine; Coc | 2011 |
The effects of 'ecstasy' (MDMA) on visuospatial memory performance: findings from a systematic review with meta-analyses.
Topics: Animals; Executive Function; Hallucinogens; Humans; Memory Disorders; Memory, Short-Term; Mental Rec | 2012 |
Specific memory deficits in ecstasy users? The results of a meta-analysis.
Topics: Attention; Hallucinogens; Humans; Memory Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Neurotox | 2003 |
Neurotoxicity of methylenedioxyamphetamines (MDMA; ecstasy) in humans: how strong is the evidence for persistent brain damage?
Topics: Animals; Brain Diseases; Cognition Disorders; Hallucinogens; Humans; Memory Disorders; Mental Disord | 2006 |
The confounding problem of polydrug use in recreational ecstasy/MDMA users: a brief overview.
Topics: Amphetamine-Related Disorders; Brain; Cannabinoids; Cell Survival; Cognition Disorders; Hallucinogen | 2006 |
Ecstasy (MDMA) and memory function: a meta-analytic update.
Topics: Cannabis; Databases, Factual; Hallucinogens; Humans; Illicit Drugs; Memory Disorders; Memory, Short- | 2007 |
Long term psychiatric and cognitive effects of MDMA use.
Topics: Chronic Disease; Cognition Disorders; Hallucinogens; Humans; Memory Disorders; Mental Recall; N-Meth | 2000 |
Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity.
Topics: Animals; Cognition Disorders; Humans; Memory Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Neur | 2002 |
9 trials available for n-methyl-3,4-methylenedioxyamphetamine and Memory Disorders
| Article | Year |
|---|---|
Remembering Molly: Immediate and delayed false memory formation after acute MDMA exposure.
Topics: Animals; Humans; Imagination; Memory Disorders; Memory, Episodic; Mental Recall; N-Methyl-3,4-methyl | 2022 |
Peripheral endocannabinoid concentrations are not associated with verbal memory impairment during MDMA intoxication.
Topics: Adult; Arachidonic Acids; Double-Blind Method; Endocannabinoids; Female; Humans; Ketanserin; Male; M | 2018 |
Involvement of inferior parietal lobules in prospective memory impairment during acute MDMA (ecstasy) intoxication: an event-related fMRI study.
Topics: Adult; Analysis of Variance; Brain Mapping; Cross-Over Studies; Double-Blind Method; Electroencephal | 2009 |
Blockade of 5-HT2 receptor selectively prevents MDMA-induced verbal memory impairment.
Topics: Adult; Double-Blind Method; Female; Humans; Male; Memory Disorders; N-Methyl-3,4-methylenedioxyamphe | 2011 |
MDMA intoxication and verbal memory performance: a placebo-controlled pharmaco-MRI study.
Topics: Adult; Brain Mapping; Cross-Over Studies; Double-Blind Method; Female; Frontal Lobe; Hallucinogens; | 2011 |
Inhibition of MDMA-induced increase in cortisol does not prevent acute impairment of verbal memory.
Topics: Adult; Amphetamine-Related Disorders; Double-Blind Method; Female; Hallucinogens; Humans; Hydrocorti | 2013 |
Cognitive function and mood in MDMA/THC users, THC users and non-drug using controls.
Topics: Adult; Amphetamine-Related Disorders; Anxiety; Cognition Disorders; Decision Making; Depression; Dis | 2006 |
Prospective memory impairment in "ecstasy" (MDMA) users.
Topics: Adult; Analysis of Variance; Female; Humans; Male; Marijuana Abuse; Memory Disorders; N-Methyl-3,4-m | 2007 |
Working memory deficits in current and previous users of MDMA ('ecstasy').
Topics: Adult; Cognition; Hallucinogens; Humans; Memory Disorders; Memory, Short-Term; Multivariate Analysis | 2000 |
75 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Memory Disorders
| Article | Year |
|---|---|
Recreational drug use and prospective memory.
Topics: Female; Humans; Memory Disorders; Memory, Episodic; N-Methyl-3,4-methylenedioxyamphetamine; Neuropsy | 2022 |
The functional connectome of 3,4-methyldioxymethamphetamine-related declarative memory impairments.
Topics: Brain; Connectome; Humans; Magnetic Resonance Imaging; Memory; Memory Disorders; N-Methyl-3,4-methyl | 2023 |
Dose concentration and spatial memory and brain mitochondrial function association after 3,4-methylenedioxymethamphetamine (MDMA) administration in rats.
Topics: Animals; Brain; Cognition; Cytochromes c; Dose-Response Relationship, Drug; Hallucinogens; Humans; M | 2020 |
Treadmill exercise attenuates 3,4-methylenedioxymethamphetamine-induced memory impairment through a decrease apoptosis in male rat hippocampus.
Topics: Animals; Apoptosis; Hippocampus; Male; Maze Learning; Memory Disorders; N-Methyl-3,4-methylenedioxya | 2017 |
Widespread reduction of dopamine cell bodies and terminals in adult rats exposed to a low dose regimen of MDMA during adolescence.
Topics: Animals; Brain; Caffeine; Cell Body; Cell Count; Dopaminergic Neurons; Drug Interactions; Fluorescen | 2017 |
Discrete memory impairments in largely pure chronic users of MDMA.
Topics: Adult; Amphetamine-Related Disorders; Chronic Disease; Comorbidity; Female; Hair; Hallucinogens; Hum | 2017 |
Effects of MDMA on neuroplasticity, amyloid burden and phospho-tau expression in APPswe/PS1dE9 mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cognitive Dysfunction; Disease Models, Ani | 2019 |
Memory impairment and hippocampus specific protein oxidation induced by ethanol intake and 3, 4-methylenedioxymethamphetamine (MDMA) in mice.
Topics: Animals; Ethanol; Hippocampus; Male; Maze Learning; Membrane Proteins; Memory Disorders; Mice; N-Met | 2013 |
Verbal memory deficits are correlated with prefrontal hypometabolism in (18)FDG PET of recreational MDMA users.
Topics: Adult; Brain Mapping; Fluorodeoxyglucose F18; Humans; Male; Memory Disorders; Mental Recall; N-Methy | 2013 |
Depression, impulsiveness, sleep, and memory in past and present polydrug users of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy).
Topics: Adolescent; Adult; Alcohol-Related Disorders; Amphetamine-Related Disorders; Attitude to Health; Dep | 2014 |
MDMA enhances hippocampal-dependent learning and memory under restrictive conditions, and modifies hippocampal spine density.
Topics: Animals; Body Temperature; Body Weight; CA1 Region, Hippocampal; Dendritic Spines; Male; Maze Learni | 2014 |
Temporal and visual source memory deficits among ecstasy/polydrug users.
Topics: Cocaine-Related Disorders; Female; Hallucinogens; Humans; Illicit Drugs; Judgment; Male; Memory; Mem | 2014 |
Prenatal exposure to alcohol and 3,4-methylenedioxymethamphetamine (ecstasy) alters adult hippocampal neurogenesis and causes enduring memory deficits.
Topics: Animals; Behavior, Animal; Doublecortin Protein; Ethanol; Exploratory Behavior; Female; Hippocampus; | 2014 |
MDMA is certainly damaging after 25 years of empirical research: a reply and refutation of Doblin et al. (2014).
Topics: Animals; Empirical Research; Hallucinogens; Humans; Illicit Drugs; Memory Disorders; N-Methyl-3,4-me | 2014 |
A reconsideration and response to Parrott AC (2013) "Human psychobiology of MDMA or 'Ecstasy': an overview of 25 years of empirical research".
Topics: Animals; Empirical Research; Hallucinogens; Humans; Illicit Drugs; Memory Disorders; N-Methyl-3,4-me | 2014 |
Dysfunctional overnight memory consolidation in ecstasy users.
Topics: Adult; Case-Control Studies; Drug Users; Executive Function; Female; Humans; Learning; Male; Memory | 2014 |
Memory and mood during MDMA intoxication, with and without memantine pretreatment.
Topics: Affect; Amphetamine-Related Disorders; Central Nervous System Stimulants; Double-Blind Method; Femal | 2014 |
The disruptive effects of methamphetamine on delayed-matching-to-sample performance reflect proactive interference and are reduced by SCH23390.
Topics: Amphetamine-Related Disorders; Animals; Benzazepines; Central Nervous System Stimulants; Disease Mod | 2015 |
Reduced memory skills and increased hair cortisol levels in recent Ecstasy/MDMA users: significant but independent neurocognitive and neurohormonal deficits.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Cognition Disorders; Female; Hair; Hallucinogens; | 2015 |
Neural and behavioural changes in male periadolescent mice after prolonged nicotine-MDMA treatment.
Topics: Animals; Behavior, Animal; Body Weight; Drug Interactions; Hallucinogens; Hippocampus; Lipid Peroxid | 2016 |
Adaptive Plasticity in the Hippocampus of Young Mice Intermittently Exposed to MDMA Could Be the Origin of Memory Deficits.
Topics: Aging; Animals; Biomarkers; Brain-Derived Neurotrophic Factor; Hippocampus; Male; Memory; Memory Dis | 2016 |
Ecstasy-related deficits in the updating component of executive processes.
Topics: Adult; Amphetamine-Related Disorders; Female; Humans; Male; Memory Disorders; Mental Recall; N-Methy | 2008 |
High suicide risk after the development of cognitive and working memory deficits caused by cannabis, cocaine and ecstasy use.
Topics: Adult; Cocaine-Related Disorders; Cognition Disorders; Humans; Male; Marijuana Abuse; Memory Disorde | 2007 |
Learning and memory deficits in ecstasy users and their neural correlates during a face-learning task.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Association Learning; Brain; Brain Mapping; Cannab | 2009 |
Long-term neuropsychological effects of ecstasy in middle-aged ecstasy/polydrug users.
Topics: Adult; Age Factors; Attention; Cross-Sectional Studies; Depression; Female; Hallucinogens; Humans; I | 2010 |
A cannabinoid CB(1) receptor antagonist ameliorates impairment of recognition memory on withdrawal from MDMA (Ecstasy).
Topics: Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Admini | 2010 |
Everyday and prospective memory deficits in ecstasy/polydrug users.
Topics: Cognition; Cognition Disorders; Comprehension; Female; Humans; Illicit Drugs; Male; Memory; Memory D | 2011 |
Procedural and declarative memory task performance, and the memory consolidation function of sleep, in recent and abstinent ecstasy/MDMA users.
Topics: Adult; Amphetamine-Related Disorders; Cognition; Cognition Disorders; Female; Humans; Illicit Drugs; | 2011 |
Ecstasy overdose and memory loss.
Topics: Hippocampus; Humans; Male; Memory Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Prescription Dr | 2010 |
Evidence of neurotoxicity of ecstasy: sustained effects on electroencephalographic activity in polydrug users.
Topics: Adolescent; Adult; Alpha Rhythm; Attention Deficit Disorder with Hyperactivity; Electroencephalograp | 2010 |
Novel object recognition memory: measurement issues and effects of MDMA self-administration following short inter-trial intervals.
Topics: Animals; Exploratory Behavior; Hallucinogens; Male; Memory Disorders; N-Methyl-3,4-methylenedioxyamp | 2011 |
Prospective memory functioning among ecstasy/polydrug users: evidence from the Cambridge Prospective Memory Test (CAMPROMPT).
Topics: Amphetamine-Related Disorders; Cannabis; Case-Control Studies; Female; Humans; Male; Marijuana Abuse | 2011 |
Prospective memory deficits in Ecstasy users: effects of longer ongoing task delay interval.
Topics: Adolescent; Adult; Alcohols; Analysis of Variance; Female; Humans; Male; Memory Disorders; Memory, E | 2011 |
A prospective study of learning, memory, and executive function in new MDMA users.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Analysis of Variance; Executive Function; Female; | 2013 |
Neuropsychological evidence of a relatively selective profile of temporal dysfunction in drug-free MDMA ("ecstasy") polydrug users.
Topics: Adolescent; Adult; Association Learning; Attention; Cognition Disorders; Decision Making; Female; Ha | 2002 |
Ecstasy/MDMA attributed problems reported by novice, moderate and heavy recreational users.
Topics: Anxiety; Depression; Humans; Illicit Drugs; Internet; Memory Disorders; N-Methyl-3,4-methylenedioxya | 2002 |
The impact of regular ecstasy use on memory function.
Topics: Adult; Female; Hallucinogens; Health Status; Humans; Male; Memory Disorders; Mental Health; N-Methyl | 2002 |
Cannabis, ecstasy/MDMA and memory: a commentary on Simon & Mattick's recent study.
Topics: Cannabis; Hallucinogens; Humans; Memory Disorders; N-Methyl-3,4-methylenedioxyamphetamine | 2003 |
Memory impairment suggests hippocampal dysfunction in abstinent ecstasy users.
Topics: Adult; Analysis of Variance; Cognition Disorders; Female; Hippocampus; Humans; Male; Memory Disorder | 2003 |
Donepezil in a chronic drug user--a potential treatment?
Topics: Adult; Amphetamine-Related Disorders; Attention; Cholinesterase Inhibitors; Donepezil; Dose-Response | 2003 |
Reduced cortical gray matter density in human MDMA (Ecstasy) users: a voxel-based morphometry study.
Topics: Adolescent; Adult; Brain Mapping; Cerebral Cortex; Female; Humans; Illicit Drugs; Image Processing, | 2003 |
Patterns of drug use and the influence of gender on self-reports of memory ability in ecstasy users: a web-based study.
Topics: Amphetamine-Related Disorders; Cannabis; Dose-Response Relationship, Drug; Drug Administration Sched | 2003 |
Neurocognitive function in users of MDMA: the importance of clinically significant patterns of use.
Topics: Adolescent; Adult; Brain; Cognition Disorders; Depression; Diagnostic and Statistical Manual of Ment | 2004 |
Verbal working memory deficits in current and previous users of MDMA.
Topics: Adult; Alcoholism; Comprehension; Female; Hallucinogens; Humans; Male; Marijuana Abuse; Mathematics; | 2004 |
Memory-related hippocampal dysfunction in poly-drug ecstasy (3,4-methylenedioxymethamphetamine) users.
Topics: Adult; Amphetamine; Brain Mapping; Cannabis; Female; Hallucinogens; Hippocampus; Humans; Magnetic Re | 2005 |
Persistent neuropsychological problems after 7 years of abstinence from recreational Ecstasy (MDMA): a case study.
Topics: Adrenergic Uptake Inhibitors; Adult; Depressive Disorder; Erectile Dysfunction; Follow-Up Studies; H | 2004 |
Differential effects of MDMA, cocaine, and cannabis use severity on distinctive components of the executive functions in polysubstance users: a multiple regression analysis.
Topics: Adult; Alcoholism; Cocaine-Related Disorders; Cognition Disorders; Female; Humans; Male; Marijuana A | 2005 |
Memory deficit and reduced anxiety in young adult rats given repeated intermittent MDMA treatment during the periadolescent period.
Topics: Age Factors; Animals; Anxiety; Male; Membrane Glycoproteins; Membrane Transport Proteins; Memory Dis | 2004 |
Visuo-spatial working memory deficits in current and former users of MDMA ('ecstasy').
Topics: Adult; Age Factors; Alcohol Drinking; Analysis of Variance; Educational Status; Hallucinogens; Human | 2005 |
Effect of ecstasy use on neuropsychological function: a study in Hong Kong.
Topics: Adolescent; Adult; Attention; Female; Hong Kong; Humans; Male; Memory; Memory Disorders; Middle Aged | 2005 |
Memory performance in polyvalent MDMA (ecstasy) users who continue or discontinue MDMA use.
Topics: Adult; Brain; Cross-Sectional Studies; Demography; Female; Follow-Up Studies; Hallucinogens; Humans; | 2005 |
The differential effects of ecstasy/polydrug use on executive components: shifting, inhibition, updating and access to semantic memory.
Topics: Adult; Cognition; Female; Humans; Male; Memory; Memory Disorders; N-Methyl-3,4-methylenedioxyampheta | 2005 |
Co-administration of THC and MDMA ('ecstasy') synergistically disrupts memory in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Discrimination, Psychological; Dronabinol; Drug Com | 2005 |
Drug-facilitated rape.
Topics: Alcohol Drinking; Crime Victims; Flunitrazepam; Forensic Medicine; Humans; Memory Disorders; N-Methy | 2002 |
Chronic ecstasy (MDMA) use is associated with deficits in task-switching but not inhibition or memory updating executive functions.
Topics: Adult; Chronic Disease; Cognition Disorders; Female; Humans; Inhibition, Psychological; Male; Memory | 2006 |
3,4-Methylenedioxymethamphetamine in adult rats produces deficits in path integration and spatial reference memory.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cognition; Hallucinogens; Learning; Male; Maze Lear | 2006 |
Memory impairment in now abstinent MDMA users and continued users: a longitudinal follow-up.
Topics: Adult; Follow-Up Studies; Humans; Longitudinal Studies; Memory; Memory Disorders; N-Methyl-3,4-methy | 2006 |
Memory deficits in abstinent MDMA (ecstasy) users: neuropsychological evidence of frontal dysfunction.
Topics: Adult; Amphetamine-Related Disorders; Cannabinoids; Dose-Response Relationship, Drug; Frontal Lobe; | 2006 |
Patterns of memory dysfunction in current and 2-year abstinent MDMA users.
Topics: Adult; Analysis of Variance; Demography; Female; Hallucinogens; Humans; Male; Memory Disorders; Memo | 2006 |
Cognitive performance in light current users and ex-users of ecstasy (MDMA) and controls.
Topics: Adult; Analysis of Variance; Case-Control Studies; Cognition Disorders; Female; Humans; Male; Memory | 2007 |
Cognition in novice ecstasy users with minimal exposure to other drugs: a prospective cohort study.
Topics: Adult; Attention; Cannabis; Cognition; Cognition Disorders; Cohort Studies; Female; Follow-Up Studie | 2007 |
Neurocognitive function in current and ex-users of ecstasy in comparison to both matched polydrug-using controls and drug-naïve controls.
Topics: Adult; Case-Control Studies; Cognition Disorders; Hallucinogens; Humans; Illicit Drugs; Learning; Ma | 2007 |
Everyday memory deficits in ecstasy-polydrug users.
Topics: Adult; Cannabis; Cognition Disorders; Female; Hallucinogens; Humans; Illicit Drugs; Linear Models; M | 2007 |
Cognitive performance in recreational ecstasy polydrug users: a two-year follow-up study.
Topics: Adult; Cognition Disorders; Drug Synergism; Female; Follow-Up Studies; Hallucinogens; Humans; Illici | 2008 |
Metamemory in recreational ecstasy polydrug users: what do self-reports of memory failures mean?
Topics: Adolescent; Adult; Cognition; Cohort Studies; Cross-Sectional Studies; Female; Humans; Male; Memory | 2008 |
[Brain functional disorders after taking Ecstasy?].
Topics: Adult; Brain Diseases; Female; Humans; Memory Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Sub | 1995 |
Ecstasy (MDMA) effects upon mood and cognition: before, during and after a Saturday night dance.
Topics: Adult; Affect; Analysis of Variance; Cognition; Dancing; Female; Hallucinogens; Humans; Male; Memory | 1998 |
Memory deficits associated with recreational use of "ecstasy" (MDMA).
Topics: Adult; Female; Hallucinogens; Humans; Illicit Drugs; Male; Memory Disorders; Memory, Short-Term; Men | 1999 |
Memory disturbances in "Ecstasy" users are correlated with an altered brain serotonin neurotransmission.
Topics: Adult; Brain; Female; Humans; Male; Memory Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Piperi | 2000 |
Functional consequences of repeated (+/-)3,4-methylenedioxymethamphetamine (MDMA) treatment in rhesus monkeys.
Topics: Animals; Behavior, Animal; Brain; Cognition; Dose-Response Relationship, Drug; Evoked Potentials, Au | 2001 |
Memory impairment in abstinent MDMA ("Ecstasy") users: a longitudinal investigation.
Topics: Adolescent; Adult; Female; Humans; Longitudinal Studies; Male; Memory Disorders; N-Methyl-3,4-methyl | 2001 |
Cortical serotonin transporter density and verbal memory in individuals who stopped using 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy"): preliminary findings.
Topics: Adult; Brain Chemistry; Carrier Proteins; Cerebral Cortex; Cocaine; Female; Follow-Up Studies; Human | 2001 |
"Ecstasy" and serotonin neurotoxicity: new findings raise more questions.
Topics: Brain Chemistry; Carrier Proteins; Cerebral Cortex; Cocaine; Follow-Up Studies; Humans; Membrane Gly | 2001 |
Increased anxiety and impaired memory in rats 3 months after administration of 3,4-methylenedioxymethamphetamine ("ecstasy").
Topics: Animals; Anxiety; Body Temperature; Illicit Drugs; Male; Maze Learning; Memory Disorders; Motor Acti | 2001 |
Ecstasy (MDMA): are the psychological problems associated with its use reversed by prolonged abstinence?
Topics: Adult; Analysis of Variance; Cognition Disorders; Female; Hallucinogens; Humans; Impulsive Behavior; | 2002 |