n-methyl-3,4-methylenedioxyamphetamine has been researched along with MPTP Neurotoxicity Syndrome in 5 studies
N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The results demonstrate that chronic administration of MDMA during late adolescence in mice exacerbates the neurodegeneration and neuroinflammation caused by MPTP, suggesting that MDMA may constitute a risk factor for dopaminergic neuron degeneration." | 1.39 | MPTP-induced dopamine neuron degeneration and glia activation is potentiated in MDMA-pretreated mice. ( Costa, G; Frau, L; Morelli, M; Pinna, A; Plumitallo, A; Wardas, J, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beaudoin-Gobert, M | 2 |
| Météreau, E | 2 |
| Duperrier, S | 2 |
| Thobois, S | 2 |
| Tremblay, L | 2 |
| Sgambato, V | 1 |
| Costa, G | 2 |
| Frau, L | 1 |
| Wardas, J | 1 |
| Pinna, A | 1 |
| Plumitallo, A | 1 |
| Morelli, M | 2 |
| Simola, N | 1 |
| Epinat, J | 1 |
| Neumane, S | 1 |
| Ballanger, B | 1 |
| Lavenne, F | 1 |
| Liger, F | 1 |
| Tourvielle, C | 1 |
| Bonnefoi, F | 1 |
| Costes, N | 1 |
| Bars, DL | 1 |
| Broussolle, E | 1 |
| Sgambato-Faure, V | 1 |
| Huot, P | 1 |
| Johnston, TH | 1 |
| Lewis, KD | 1 |
| Koprich, JB | 1 |
| Reyes, MG | 1 |
| Fox, SH | 1 |
| Piggott, MJ | 1 |
| Brotchie, JM | 1 |
5 other studies available for n-methyl-3,4-methylenedioxyamphetamine and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
Pathophysiology of levodopa-induced dyskinesia: Insights from multimodal imaging and immunohistochemistry in non-human primates.
Topics: Animals; Brain; Diffusion Tensor Imaging; Disease Models, Animal; Dopamine Agents; Dyskinesia, Drug- | 2018 |
MPTP-induced dopamine neuron degeneration and glia activation is potentiated in MDMA-pretreated mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Brain; CD11b Antigen; Cell Count; Disease Models, Animal; Dop | 2013 |
MDMA administration during adolescence exacerbates MPTP-induced cognitive impairment and neuroinflammation in the hippocampus and prefrontal cortex.
Topics: Animals; Astrocytes; CD11b Antigen; Cognition; Cognition Disorders; Glial Fibrillary Acidic Protein; | 2014 |
Behavioural impact of a double dopaminergic and serotonergic lesion in the non-human primate.
Topics: Aniline Compounds; Animals; Antiparkinson Agents; Brain; Brain Mapping; Chlorocebus aethiops; Diseas | 2015 |
Characterization of 3,4-methylenedioxymethamphetamine (MDMA) enantiomers in vitro and in the MPTP-lesioned primate: R-MDMA reduces severity of dyskinesia, whereas S-MDMA extends duration of ON-time.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Behavior, Animal; Brain; Callithrix; Dyskinesia | 2011 |