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n-methyl-3,4-methylenedioxyamphetamine and MODS

n-methyl-3,4-methylenedioxyamphetamine has been researched along with MODS in 18 studies

N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
" Following initial improvement, she developed delayed rhabdomyolysis then haloperidol-induced neuroleptic malignant syndrome, which was treated with a total of 50 mg."3.78Ecstacy-induced delayed rhabdomyolysis and neuroleptic malignant syndrome in a patient with a novel variant in the ryanodine receptor type 1 gene. ( Hawryluck, LA; Kraeva, N; Riazi, S; Russell, T; Steel, AC, 2012)
" We report a case of combined ecstasy/cocaine-induced fulminant hepatic failure presenting with severe rhabdomyolysis, myocardial infarction and multiorgan failure."3.72Successful treatment of refractory cerebral oedema in ecstasy/cocaine-induced fulminant hepatic failure using a new high-efficacy liver detoxification device (FPSA-Prometheus). ( Bauer, E; Kramer, L; Mallek, R; Schenk, P; Steininger, R; Vigl, M, 2003)
" The molecular mechanisms involved in the genesis of these toxic effects are not yet fully clarified, but the oxidative stress, excitotoxicity, and mitochondrial dysfunction appear to be causal events that converge to mediate MDMA-induced toxicity."2.46MDMA toxicity and pathological consequences: a review about experimental data and autopsy findings. ( Bello, S; Fineschi, V; Neri, M; Riezzo, I; Turillazzi, E, 2010)
" Clinically important toxic effects have been reported, including fatalities."2.43Acute toxic effects of 'Ecstasy' (MDMA) and related compounds: overview of pathophysiology and clinical management. ( Hall, AP; Henry, JA, 2006)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (16.67)18.2507
2000's9 (50.00)29.6817
2010's6 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vakde, T1
Diaz, M1
Uday, K1
Duncalf, R1
Shelton, CP1
Rosini, JM1
Dahl, MK1
Johansen, SS1
Ramlau, J1
Jensen, KA1
Gee, P1
Jerram, T1
Bowie, D1
Song, BJ1
Moon, KH1
Upreti, VV1
Eddington, ND1
Lee, IJ1
Turillazzi, E1
Riezzo, I1
Neri, M1
Bello, S1
Fineschi, V1
Russell, T1
Riazi, S1
Kraeva, N1
Steel, AC1
Hawryluck, LA1
Kramer, L1
Bauer, E1
Schenk, P1
Steininger, R1
Vigl, M1
Mallek, R1
Ben-Abraham, R1
Szold, O1
Rudick, V1
Weinbroum, AA1
Lukasik-Głebocka, M1
Wachowiak, R1
Kostrzewa, A1
Karlikowski, M1
Mańkowski, W1
Kołowski, J1
Hall, AP2
Henry, JA1
Strobbe, L1
de Jaer, CP1
Louwerse, ES1
Rozendaal, FW1
Schilder, JN1
Feldman, KW1
Mazor, S1
de Man, RA1
Murthy, BV1
Wilkes, RG1
Roberts, NB1
Trejo Gutiérrez, O1
Ortega Romero, M1
Perea Gainza, M1
Nogué Xarau, S1

Reviews

4 reviews available for n-methyl-3,4-methylenedioxyamphetamine and MODS

ArticleYear
Mechanisms of MDMA (ecstasy)-induced oxidative stress, mitochondrial dysfunction, and organ damage.
    Current pharmaceutical biotechnology, 2010, Volume: 11, Issue:5

    Topics: Animals; Hallucinogens; Humans; Mitochondria; Models, Biological; Multiple Organ Failure; N-Methyl-3

2010
MDMA toxicity and pathological consequences: a review about experimental data and autopsy findings.
    Current pharmaceutical biotechnology, 2010, Volume: 11, Issue:5

    Topics: Animals; Humans; Metabolic Clearance Rate; Multiple Organ Failure; N-Methyl-3,4-methylenedioxyamphet

2010
Acute toxic effects of 'Ecstasy' (MDMA) and related compounds: overview of pathophysiology and clinical management.
    British journal of anaesthesia, 2006, Volume: 96, Issue:6

    Topics: Adolescent; Adult; Death, Sudden; Fever; Hallucinogens; Humans; Hyponatremia; Multiple Organ Failure

2006
[Morbidity and mortality caused by use of ecstasy].
    Nederlands tijdschrift voor geneeskunde, 1994, Sep-10, Volume: 138, Issue:37

    Topics: Chemical and Drug Induced Liver Injury; Humans; Multiple Organ Failure; N-Methyl-3,4-methylenedioxya

1994

Other Studies

14 other studies available for n-methyl-3,4-methylenedioxyamphetamine and MODS

ArticleYear
Rapidly reversible multiorgan failure after ingestion of "Molly" (pure 3,4-methylenedioxymethamphetamine): a case report.
    Journal of medical case reports, 2014, Jun-18, Volume: 8

    Topics: Acute Kidney Injury; Adult; Heart Failure; Humans; Illicit Drugs; Male; Multiple Organ Failure; N-Me

2014
Multisystem Organ Failure and Death Resulting From Ingestion of "Molly" (3,4-Methylenedioxymethamphetamine).
    Journal of emergency nursing, 2015, Volume: 41, Issue:5

    Topics: Adult; Emergency Nursing; Emergency Service, Hospital; Fatal Outcome; Humans; Illicit Drugs; Male; M

2015
[Survival after severe ecstasy intoxication].
    Ugeskrift for laeger, 2008, Nov-03, Volume: 170, Issue:45

    Topics: Adult; Brain Damage, Chronic; Drug Overdose; Forensic Toxicology; Hallucinogens; Humans; Male; Multi

2008
Multiorgan failure from 1-benzylpiperazine ingestion--legal high or lethal high?
    Clinical toxicology (Philadelphia, Pa.), 2010, Volume: 48, Issue:3

    Topics: Drug Synergism; Female; Hallucinogens; Humans; Illicit Drugs; Male; Multiple Organ Failure; N-Methyl

2010
Ecstacy-induced delayed rhabdomyolysis and neuroleptic malignant syndrome in a patient with a novel variant in the ryanodine receptor type 1 gene.
    Anaesthesia, 2012, Volume: 67, Issue:9

    Topics: Anesthetics, Inhalation; Antipsychotic Agents; Body Temperature; Caffeine; Central Nervous System St

2012
Successful treatment of refractory cerebral oedema in ecstasy/cocaine-induced fulminant hepatic failure using a new high-efficacy liver detoxification device (FPSA-Prometheus).
    Wiener klinische Wochenschrift, 2003, Sep-15, Volume: 115, Issue:15-16

    Topics: Adult; Ammonia; Brain Edema; Cocaine; Encephalocele; Follow-Up Studies; Hepatic Encephalopathy; Huma

2003
'Ecstasy' intoxication: life-threatening manifestations and resuscitative measures in the intensive care setting.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2003, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Coma; Critical Care; Female; Hallucinogens; Humans; Illicit Drugs; Israel; Male;

2003
[Clinical and toxicological evaluation of fatal poisoning with amphetamine derivative--MDMA, ecstasy (3,4-methylenedioxymethamphetamine)].
    Przeglad lekarski, 2004, Volume: 61, Issue:4

    Topics: Acute Kidney Injury; Adolescent; Disseminated Intravascular Coagulation; Fatal Outcome; Humans; Live

2004
[Fatal ecstasy intoxication in a 22-year-old man].
    Nederlands tijdschrift voor geneeskunde, 2007, Jul-28, Volume: 151, Issue:30

    Topics: Adult; Fatal Outcome; Fever; Hallucinogens; Humans; Male; Multiple Organ Failure; N-Methyl-3,4-methy

2007
[Fatal ecstasy intoxication in a 22-year-old man].
    Nederlands tijdschrift voor geneeskunde, 2007, Oct-13, Volume: 151, Issue:41

    Topics: Adult; Hallucinogens; Humans; Male; Multiple Organ Failure; N-Methyl-3,4-methylenedioxyamphetamine

2007
Ecstasy ingestion causing heatstroke-like, multiorgan injury in a toddler.
    Pediatric emergency care, 2007, Volume: 23, Issue:10

    Topics: Administration, Oral; Child, Preschool; Follow-Up Studies; Humans; Male; Multiple Organ Failure; N-M

2007
Creatine kinase isoform changes following Ecstasy overdose.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:2

    Topics: Creatine Kinase; Drug Overdose; Humans; Illicit Drugs; Isoenzymes; Male; Multiple Organ Failure; N-M

1997
Ecstasy: creatinine kinase.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Creatine Kinase; Dantrolene; Designer Drugs; Fever; Humans; Multiple

1997
[Multiple organ failure associated with use of ecstasy].
    Revista clinica espanola, 2001, Volume: 201, Issue:2

    Topics: Acute Disease; Adolescent; Hallucinogens; Humans; Male; Multiple Organ Failure; N-Methyl-3,4-methyle

2001