n-methyl-3,4-methylenedioxyamphetamine has been researched along with Hyponatremia in 47 studies
N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.
Hyponatremia: Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Clinically important toxic effects have been reported, including fatalities." | 2.43 | Acute toxic effects of 'Ecstasy' (MDMA) and related compounds: overview of pathophysiology and clinical management. ( Hall, AP; Henry, JA, 2006) |
| " A mistaken belief that it is a safe drug of low toxicity and a long duration of action has led to its widespread popularity among teenagers and young adults in recent years." | 2.43 | [Ecstasy toxicity]. ( Reingardiene, D, 2006) |
| " However, reports of adverse effects and fatalities have increased in the medical and popular press." | 2.41 | Agony and ecstasy: a review of MDMA effects and toxicity. ( Burgess, C; Gill, M; O'Donohoe, A, 2000) |
| "The management of hyperthermia is of particular importance, as time to correction, particularly at temperatures greater than 106 °F, is directly associated with increased risk of morbidity and mortality." | 1.62 | Sympathomimetic-Induced Hyperthermia and Hyponatremia: A Simulation Case for Emergency Medicine Residents. ( Black, E; Sergel, M; Winfield, A, 2021) |
| "Hyponatremia was defined as a measured serum sodium level less than 130 mmol/L." | 1.34 | Patterns of ecstasy-associated hyponatremia in California. ( Blanc, P; Olson, KR; Rosenson, J; Smollin, C; Sporer, KA, 2007) |
| "Her hyponatremia was slowly corrected." | 1.32 | Transient proximal tubular renal injury following Ecstasy ingestion. ( Dharnidharka, VR; Kwon, C; Zaritsky, A, 2003) |
| "Hyponatremia is also reported, and its manifestations are frequently delayed several hours after the drug is ingested." | 1.31 | The "ecstasy" hangover: hyponatremia due to 3,4-methylenedioxymethamphetamine. ( Hoffman, RS; Nelson, LS; Traub, SJ, 2002) |
| "A patient presented to our unit with seizures and profound hyponatraemia after ingestion of a single tablet of ecstasy." | 1.30 | Hyponatraemia and seizures after ecstasy use. ( Alexander, WD; Banerjee, AK; Holmes, SB, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (25.53) | 18.2507 |
| 2000's | 20 (42.55) | 29.6817 |
| 2010's | 13 (27.66) | 24.3611 |
| 2020's | 2 (4.26) | 2.80 |
| Authors | Studies |
|---|---|
| Faria, AC | 1 |
| Carmo, H | 1 |
| Carvalho, F | 1 |
| Silva, JP | 1 |
| Bastos, ML | 1 |
| Dias da Silva, D | 1 |
| Winfield, A | 1 |
| Black, E | 1 |
| Sergel, M | 1 |
| Armitage, MC | 1 |
| Bryant, RJ | 1 |
| Page, CB | 1 |
| Salathe, C | 1 |
| Blanc, AL | 1 |
| Tagan, D | 1 |
| van Dijken, GD | 1 |
| Blom, RE | 1 |
| Hené, RJ | 1 |
| Boer, WH | 1 |
| Moritz, ML | 1 |
| Kalantar-Zadeh, K | 2 |
| Ayus, JC | 1 |
| Zieg, J | 1 |
| Ligtenberg, JJ | 1 |
| Olgers, TJ | 1 |
| van de Meeberg, EK | 1 |
| ter Maaten, JC | 1 |
| Kazory, A | 2 |
| Baumann, S | 1 |
| Becher, T | 1 |
| Frambach, D | 1 |
| Wenz, H | 1 |
| Kirschning, T | 1 |
| Borggrefe, M | 1 |
| Rapp, S | 1 |
| Akin, I | 1 |
| Campbell, GA | 1 |
| Rosner, MH | 1 |
| Niemeijer, ND | 1 |
| van Guldener, C | 1 |
| van Wijngaarden, P | 1 |
| Ghatol, A | 1 |
| Aramendi, I | 1 |
| Manzanares, W | 1 |
| Claffey, C | 1 |
| Aitchison, KJ | 1 |
| Tsapakis, EM | 1 |
| Huezo-Diaz, P | 1 |
| Kerwin, RW | 1 |
| Forsling, ML | 1 |
| Wolff, K | 2 |
| Aitchison, K | 1 |
| Traub, SJ | 1 |
| Hoffman, RS | 1 |
| Nelson, LS | 1 |
| Sue, YM | 1 |
| Lee, YL | 1 |
| Huang, JJ | 1 |
| Kwon, C | 1 |
| Zaritsky, A | 1 |
| Dharnidharka, VR | 1 |
| Budisavljevic, MN | 1 |
| Stewart, L | 1 |
| Sahn, SA | 1 |
| Ploth, DW | 1 |
| Brvar, M | 1 |
| Kozelj, G | 1 |
| Osredkar, J | 1 |
| Mozina, M | 1 |
| Gricar, M | 1 |
| Bunc, M | 1 |
| Campbell, S | 1 |
| Qureshi, T | 1 |
| Morán Chorro, I | 1 |
| Marruecos Sant, L | 1 |
| Delgado Martín, MO | 1 |
| Hoorn, EJ | 1 |
| Halperin, ML | 2 |
| Zietse, R | 1 |
| Rukskul, P | 1 |
| Hall, AP | 2 |
| Henry, JA | 5 |
| Reingardiene, D | 1 |
| Nguyen, MK | 1 |
| Chang, R | 1 |
| Kurtz, I | 1 |
| Rosenson, J | 1 |
| Smollin, C | 1 |
| Sporer, KA | 1 |
| Blanc, P | 1 |
| Olson, KR | 1 |
| Maxwell, DL | 1 |
| Polkey, MI | 1 |
| Kessel, B | 1 |
| Wilkins, B | 1 |
| Box, SA | 1 |
| Prescott, LF | 1 |
| Freestone, S | 1 |
| Parr, MJ | 2 |
| Low, HM | 1 |
| Botterill, P | 1 |
| Nuvials, X | 1 |
| Masclans, JR | 1 |
| Peracaula, R | 1 |
| de Latorre, FJ | 1 |
| Watson, ID | 1 |
| Serlin, M | 1 |
| Moncur, P | 1 |
| Tames, F | 1 |
| Fallon, JK | 1 |
| Kicman, AT | 1 |
| Hutt, AJ | 1 |
| Cowan, DA | 1 |
| Forsling, M | 1 |
| Ajaelo, I | 1 |
| Koenig, K | 1 |
| Snoey, E | 1 |
| Holmes, SB | 1 |
| Banerjee, AK | 1 |
| Alexander, WD | 1 |
| O'Connor, A | 1 |
| Cluroe, A | 1 |
| Couch, R | 1 |
| Galler, L | 1 |
| Lawrence, J | 1 |
| Synek, B | 1 |
| Burgess, C | 1 |
| O'Donohoe, A | 1 |
| Gill, M | 1 |
| Balmelli, C | 1 |
| Kupferschmidt, H | 1 |
| Rentsch, K | 1 |
| Schneemann, M | 1 |
| Hartung, TK | 1 |
| Schofield, E | 1 |
| Short, AI | 1 |
| Cherney, DZ | 1 |
| Davids, MR | 1 |
9 reviews available for n-methyl-3,4-methylenedioxyamphetamine and Hyponatremia
| Article | Year |
|---|---|
Drinking to death: Hyponatraemia induced by synthetic phenethylamines.
Topics: Alcohol Drinking; Alkaloids; Amphetamine; Drinking; Humans; Hyponatremia; Illicit Drugs; N-Methyl-3, | 2020 |
Evaluation and management of hyponatraemia in children.
Topics: Child; Exercise; Humans; Hyponatremia; Inappropriate ADH Syndrome; N-Methyl-3,4-methylenedioxyamphet | 2014 |
The agony of ecstasy: MDMA (3,4-methylenedioxymethamphetamine) and the kidney.
Topics: Acute Disease; Adolescent; Adult; Female; Hallucinogens; Humans; Hyponatremia; Kidney; Kidney Diseas | 2008 |
Hyponatremia associated with 3,4-methylenedioxymethylamphetamine ("Ecstasy") abuse.
Topics: Adolescent; Female; Humans; Hyponatremia; N-Methyl-3,4-methylenedioxyamphetamine; Sodium Chloride; S | 2003 |
Diagnostic approach to a patient with hyponatraemia: traditional versus physiology-based options.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Diuresis; Extracellular Fluid; Female; Human | 2005 |
Acute toxic effects of 'Ecstasy' (MDMA) and related compounds: overview of pathophysiology and clinical management.
Topics: Adolescent; Adult; Death, Sudden; Fever; Hallucinogens; Humans; Hyponatremia; Multiple Organ Failure | 2006 |
[Ecstasy toxicity].
Topics: Adolescent; Adult; Age Factors; Cardiovascular Diseases; Emergencies; Hallucinogens; Hospitalization | 2006 |
Metabolic consequences of drug misuse.
Topics: Cocaine-Related Disorders; Delirium; Fever; Heroin Dependence; Humans; Hyponatremia; N-Methyl-3,4-me | 2000 |
Agony and ecstasy: a review of MDMA effects and toxicity.
Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Chronic Disease; Fever; Hallucinogens; Humans; Hyponat | 2000 |
1 trial available for n-methyl-3,4-methylenedioxyamphetamine and Hyponatremia
| Article | Year |
|---|---|
Low-dose MDMA ("ecstasy") induces vasopressin secretion.
Topics: Adult; Arginine Vasopressin; Hallucinogens; Humans; Hyponatremia; Male; N-Methyl-3,4-methylenedioxya | 1998 |
37 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Hyponatremia
| Article | Year |
|---|---|
Sympathomimetic-Induced Hyperthermia and Hyponatremia: A Simulation Case for Emergency Medicine Residents.
Topics: Emergency Medicine; Humans; Hyperthermia; Hyponatremia; N-Methyl-3,4-methylenedioxyamphetamine; Symp | 2021 |
Severe hyponatremia complicated by seizure following 3,4-methylenedioxymethamphetamine ingestion.
Topics: Adolescent; Brain Diseases; Eating; Female; Fluid Therapy; Glasgow Coma Scale; Humans; Hyponatremia; | 2018 |
SIADH and water intoxication related to ecstasy.
Topics: Diagnosis, Differential; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; N-Methyl-3,4-meth | 2018 |
High incidence of mild hyponatraemia in females using ecstasy at a rave party.
Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Female; Follow-Up Studies; Hallucinogens; Hemog | 2013 |
Ecstacy-associated hyponatremia: why are women at risk?
Topics: Biomarkers; Female; Hallucinogens; Humans; Hyponatremia; Male; N-Methyl-3,4-methylenedioxyamphetamin | 2013 |
Re: MDMA-associated cerebral edema resembling psychogenic polydipsia?
Topics: Brain Edema; Diuretics, Osmotic; Female; Hallucinogens; Humans; Hyponatremia; Mannitol; N-Methyl-3,4 | 2015 |
Osmoregulatory mechanisms differentiate MDMA-associated hyponatremia from psychogenic polydipsia.
Topics: Diagnosis, Differential; Hallucinogens; Humans; Hyponatremia; N-Methyl-3,4-methylenedioxyamphetamine | 2015 |
[Hyponatremia-induced life-threatening cerebral edema after ecstasy use].
Topics: Brain Edema; Hallucinogens; Humans; Hyponatremia; N-Methyl-3,4-methylenedioxyamphetamine; Sodium; Yo | 2016 |
[Symptomatic hyponatremia after ecstasy use].
Topics: Adrenergic Uptake Inhibitors; Female; Humans; Hyponatremia; N-Methyl-3,4-methylenedioxyamphetamine; | 2009 |
Ecstasy-associated acute severe hyponatremia and cerebral edema: a role for osmotic diuresis?
Topics: Acute Disease; Brain Edema; Diuresis; Diuretics, Osmotic; Female; Hallucinogens; Humans; Hyponatremi | 2012 |
[Hyponatremic encephalopathy and brain death in Ecstasy (3,4-methylenedioxymethamphetamine) intoxication].
Topics: Brain Death; Brain Diseases; Female; Hallucinogens; Humans; Hyponatremia; N-Methyl-3,4-methylenediox | 2010 |
A 26-year-old woman with sudden onset cerebral edema.
Topics: Acute Disease; Adult; Brain Edema; Confusion; Diuretics, Osmotic; Emergency Treatment; Fatal Outcome | 2011 |
Ecstasy (MDMA)-induced hyponatraemia is associated with genetic variants in CYP2D6 and COMT.
Topics: Adolescent; Adult; Amino Acid Substitution; Biotransformation; Catechol O-Methyltransferase; Cohort | 2012 |
Reply to 'MDMA can increase cortical levels by 800% in dance clubbers' Parrott et al.
Topics: Arginine Vasopressin; Catechol O-Methyltransferase; Cytochrome P-450 CYP2D6; Female; Humans; Hydroco | 2013 |
The "ecstasy" hangover: hyponatremia due to 3,4-methylenedioxymethamphetamine.
Topics: Adult; Emergency Medical Services; Emergency Service, Hospital; Female; Hallucinogens; Humans; Hypon | 2002 |
Acute hyponatremia, seizure, and rhabdomyolysis after ecstasy use.
Topics: Adult; Female; Hallucinogens; Humans; Hyponatremia; Inappropriate ADH Syndrome; N-Methyl-3,4-methyle | 2002 |
Transient proximal tubular renal injury following Ecstasy ingestion.
Topics: Acute Disease; Adolescent; Female; Hallucinogens; Humans; Hyponatremia; Kidney Diseases; Kidney Tubu | 2003 |
Polydipsia as another mechanism of hyponatremia after 'ecstasy' (3,4 methyldioxymethamphetamine) ingestion.
Topics: Adolescent; Combined Modality Therapy; Critical Care; Emergency Service, Hospital; Female; Follow-Up | 2004 |
Taking Ecstasy... it's child's play!
Topics: Anticonvulsants; Critical Illness; Exanthema; Female; Hallucinogens; Hemodynamics; Humans; Hyponatre | 2005 |
[Hyponatremia, cerebral edema and brain death in a MDMA acute intoxication].
Topics: Adult; Amphetamine-Related Disorders; Brain Death; Brain Edema; Fatal Outcome; Female; Hallucinogens | 2005 |
Ecstasy (MDMA) ingestion related with severe hyponatremia in patients with mild head injury.
Topics: Adult; Craniocerebral Trauma; Hallucinogens; Humans; Hyponatremia; Male; N-Methyl-3,4-methylenedioxy | 2005 |
Fatal hyponatremia in a young woman after ecstasy ingestion.
Topics: Adult; Fatal Outcome; Female; Hallucinogens; Humans; Hyponatremia; N-Methyl-3,4-methylenedioxyamphet | 2006 |
Patterns of ecstasy-associated hyponatremia in California.
Topics: Adult; California; Databases, Factual; Female; Hallucinogens; Humans; Hyponatremia; Male; N-Methyl-3 | 2007 |
Hyponatraemia and catatonic stupor after taking "ecstasy".
Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Catatonia; Designer Drugs; Female; Humans; Hyponatremia; | 1993 |
Hyponatraemia after ingestion of ecstasy.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Female; Humans; Hyponatremia; N-Methyl-3,4-met | 1994 |
Cerebral oedema after MDMA ("ecstasy") and unrestricted water intake. Hyponatraemia must be treated with low water input.
Topics: Brain Edema; Drinking; Hallucinogens; Humans; Hyponatremia; N-Methyl-3,4-methylenedioxyamphetamine; | 1996 |
Hyponatraemia at a rave.
Topics: Adult; Drinking Behavior; Female; Hallucinogens; Humans; Hyponatremia; N-Methyl-3,4-methylenedioxyam | 1997 |
Hyponatraemia and death after "ecstasy" ingestion.
Topics: Adolescent; Brain Death; Brain Edema; Drug Overdose; Fatal Outcome; Female; Glasgow Coma Scale; Hall | 1997 |
Hyponatraemic coma after ecstasy ingestion.
Topics: Adult; Coma; Female; Hallucinogens; Humans; Hyponatremia; N-Methyl-3,4-methylenedioxyamphetamine | 1997 |
Acute hyponatraemia.
Topics: Adult; Female; Humans; Hyponatremia; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine | 1997 |
Hyponatraemia, water intoxication and 'ecstasy'.
Topics: Hallucinogens; Humans; Hyponatremia; N-Methyl-3,4-methylenedioxyamphetamine; Vasopressins; Water Int | 1997 |
Severe hyponatremia and inappropriate antidiuretic hormone secretion following ecstasy use.
Topics: Adult; Emergencies; Female; Hallucinogens; Humans; Hyponatremia; Inappropriate ADH Syndrome; N-Methy | 1998 |
Hyponatraemia and seizures after ecstasy use.
Topics: Adult; Furosemide; Hallucinogens; Humans; Hyponatremia; Male; N-Methyl-3,4-methylenedioxyamphetamine | 1999 |
Death from hyponatraemia-induced cerebral oedema associated with MDMA ("Ecstasy") use.
Topics: Adult; Brain Edema; Drug Overdose; Fatal Outcome; Female; Hallucinogens; Humans; Hyponatremia; N-Met | 1999 |
[Fatal brain edema after ingestion of ecstasy and benzylpiperazine].
Topics: Adult; Brain Edema; Fatal Outcome; Female; Hallucinogens; Humans; Hyponatremia; Illicit Drugs; N-Met | 2001 |
Hyponatraemic states following 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') ingestion.
Topics: Adolescent; Adult; Alcohol Drinking; Amphetamine-Related Disorders; Drinking; Female; Hallucinogens; | 2002 |
Acute hyponatraemia and 'ecstasy': insights from a quantitative and integrative analysis.
Topics: Adult; Digestive System Physiological Phenomena; Drinking; Female; Hallucinogens; Humans; Hyponatrem | 2002 |