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n-methyl-3,4-methylenedioxyamphetamine and Genetic Predisposition

n-methyl-3,4-methylenedioxyamphetamine has been researched along with Genetic Predisposition in 5 studies

N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
"After achieving predefined malignant hyperthermia criteria, standardised therapy was initiated; dantrolene sodium suspension (5 mg kg(-1)) was administered and the injection was repeated after 24 min."1.393,4-Methylenedioxymethamphetamine induces a hyperthermic and hypermetabolic crisis in pigs with and without a genetic disposition for malignant hyperthermia. ( Becker, S; Gerbershagen, MU; Oldewurtel, C; Richard, A; Schäfer, U; Schütte, JK; Singler, P; Starosse, A; Wappler, F, 2013)
"Humans with genetic predisposition for the slow metabolism of MDMA, the so-called "poor metabolizers" of debrisoquin are at higher risk."1.36Long-term neuronal damage and recovery after a single dose of MDMA: expression and distribution of serotonin transporter in the rat brain. ( Kirilly, E, 2010)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kuypers, KPC1
de la Torre, R2
Farre, M2
Xicota, L1
de Sousa Fernandes Perna, EB1
Theunissen, EL1
Ramaekers, JG1
Martín-Santos, R1
Torrens, M1
Poudevida, S1
Langohr, K1
Cuyás, E1
Pacifici, R1
Pichini, S1
Kirilly, E1
Schütte, JK1
Schäfer, U1
Becker, S1
Oldewurtel, C1
Starosse, A1
Singler, P1
Richard, A1
Wappler, F1
Gerbershagen, MU1
Marchesi, C1
Tonna, M1
Maggini, C1

Other Studies

5 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Genetic Predisposition

ArticleYear
Depressive mood ratings are reduced by MDMA in female polydrug ecstasy users homozygous for the l-allele of the serotonin transporter.
    Scientific reports, 2018, 01-18, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Affect; Alleles; Depression; Drug Users; Female; Genetic Predisposition to Diseas

2018
5-HTTLPR polymorphism, mood disorders and MDMA use in a 3-year follow-up study.
    Addiction biology, 2010, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Alleles; Amphetamine-Related Disorders; Comorbidity; Cross-Sectional Studies; Fem

2010
Long-term neuronal damage and recovery after a single dose of MDMA: expression and distribution of serotonin transporter in the rat brain.
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2010, Volume: 12, Issue:3

    Topics: Aggression; Animals; Basal Metabolism; Brain; Gene Expression Regulation; Genetic Predisposition to

2010
3,4-Methylenedioxymethamphetamine induces a hyperthermic and hypermetabolic crisis in pigs with and without a genetic disposition for malignant hyperthermia.
    European journal of anaesthesiology, 2013, Volume: 30, Issue:1

    Topics: Acidosis; Animals; Dantrolene; Fatty Acids, Nonesterified; Fever; Genetic Predisposition to Disease;

2013
Obsessive-compulsive disorder followed by psychotic episode in long-term ecstasy misuse.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Pt 2

    Topics: Adolescent; Amphetamine-Related Disorders; Antidepressive Agents, Tricyclic; Antipsychotic Agents; B

2009