n-methyl-3,4-methylenedioxyamphetamine has been researched along with Delayed Effects, Prenatal Exposure in 23 studies
N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Stimulant use, including cocaine, methamphetamines, ecstasy, and prescription stimulants, in pregnancy is increasingly common." | 5.01 | Stimulant Use in Pregnancy: An Under-recognized Epidemic Among Pregnant Women. ( Gordon, AJ; Metz, TD; Smid, MC, 2019) |
| " One of such drugs is MDMA (3,4-methylenedioxymethamphetamine) or ecstasy due to its high consumption in relevant age and sex groups and its adverse effects on human and rodent developing brains." | 2.66 | Developmental neurotoxicity of MDMA. A systematic literature review summarized in a putative adverse outcome pathway. ( Barenys, M; Fritsche, E; Gómez-Catalán, J; Masjosthusmann, S; Reverte, I, 2020) |
| "These results suggest that MDMA treatment during pregnancy and lactation causes growth retardation and dysfunction of motor neurons in mouse pups." | 1.40 | Maternal MDMA administration in mice leads to neonatal growth delay. ( Kaizaki, A; Numazawa, S; Tanaka, S; Yoshida, T, 2014) |
| "One of the most common drug abused by pregnant women is methamphetamine (MA), which is also the most frequently abused illicit drug in the Czech Republic." | 1.38 | Do prenatally methamphetamine-exposed adult male rats display general predisposition to drug abuse in the conditioned place preference test? ( Hrubá, L; Macúchová, E; Nová, E; Pometlová, M; Rokyta, R; Schutová, B; Šlamberová, R, 2012) |
| "3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) is a powerful releaser of 5-HT and chronic use of this drug can cause depletion of monoamines." | 1.35 | Developmental exposure to 3,4-methylenedioxymethamphetamine results in downregulation of neurogenesis in the adult mouse hippocampus. ( Cho, KO; Chung, SY; Kim, SY; Kwack, SJ; Rhee, GS, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 13 (56.52) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Barenys, M | 2 |
| Reverte, I | 1 |
| Masjosthusmann, S | 1 |
| Gómez-Catalán, J | 2 |
| Fritsche, E | 1 |
| Costa, G | 1 |
| Spulber, S | 1 |
| Paci, E | 1 |
| Casu, MA | 1 |
| Ceccatelli, S | 1 |
| Simola, N | 1 |
| Morelli, M | 1 |
| Macúchová, E | 3 |
| Nohejlová, K | 2 |
| Ševčíková, M | 2 |
| Hrebíčková, I | 2 |
| Šlamberová, R | 4 |
| Smid, MC | 1 |
| Metz, TD | 1 |
| Gordon, AJ | 1 |
| Kaizaki, A | 1 |
| Tanaka, S | 1 |
| Yoshida, T | 1 |
| Numazawa, S | 1 |
| Canales, JJ | 1 |
| Ferrer-Donato, A | 1 |
| McDonnell-Dowling, K | 1 |
| Kelly, JP | 1 |
| Singer, LT | 2 |
| Moore, DG | 2 |
| Min, MO | 2 |
| Goodwin, J | 2 |
| Turner, JJ | 2 |
| Fulton, S | 2 |
| Parrott, AC | 2 |
| Cho, KO | 1 |
| Rhee, GS | 2 |
| Kwack, SJ | 2 |
| Chung, SY | 1 |
| Kim, SY | 1 |
| Berman, S | 1 |
| O'Neill, J | 1 |
| Fears, S | 1 |
| Bartzokis, G | 1 |
| London, ED | 1 |
| Thompson, VB | 1 |
| Heiman, J | 1 |
| Chambers, JB | 1 |
| Benoit, SC | 1 |
| Buesing, WR | 1 |
| Norman, MK | 1 |
| Norman, AB | 1 |
| Lipton, JW | 1 |
| Joya, X | 1 |
| Papaseit, E | 1 |
| Civit, E | 1 |
| Pellegrini, M | 1 |
| Vall, O | 1 |
| Garcia-Algar, O | 1 |
| Scaravelli, G | 1 |
| Pichini, S | 1 |
| Adori, C | 1 |
| Zelena, D | 1 |
| Tímár, J | 1 |
| Gyarmati, Z | 1 |
| Domokos, A | 1 |
| Sobor, M | 1 |
| Fürst, Z | 1 |
| Makara, G | 1 |
| Bagdy, G | 1 |
| Eun, JW | 1 |
| Noh, JH | 1 |
| Jung, KH | 1 |
| Kim, JK | 1 |
| Bae, HJ | 1 |
| Xie, H | 1 |
| Ryu, JC | 1 |
| Ahn, YM | 1 |
| Park, WS | 1 |
| Lee, JY | 1 |
| Nam, SW | 1 |
| Camps, L | 1 |
| Teixido, E | 1 |
| de Lapuente, J | 1 |
| Gonzalez-Linares, J | 1 |
| Serret, J | 1 |
| Borras, M | 1 |
| Rodamilans, M | 1 |
| Llobet, JM | 1 |
| Pometlová, M | 1 |
| Schutová, B | 1 |
| Hrubá, L | 1 |
| Nová, E | 1 |
| Rokyta, R | 1 |
| Yamamotová, A | 1 |
| Kelly, PA | 1 |
| Ritchie, IM | 1 |
| Quate, L | 1 |
| McBean, DE | 1 |
| Olverman, HJ | 1 |
| Morley-Fletcher, S | 1 |
| Puopolo, M | 1 |
| Gentili, S | 1 |
| Gerra, G | 1 |
| Macchia, T | 1 |
| Laviola, G | 1 |
| Skelton, MR | 1 |
| Williams, MT | 1 |
| Vorhees, CV | 1 |
| Bronson, ME | 1 |
| Jiang, W | 1 |
| Clark, CR | 1 |
| DeRuiter, J | 1 |
5 reviews available for n-methyl-3,4-methylenedioxyamphetamine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Developmental neurotoxicity of MDMA. A systematic literature review summarized in a putative adverse outcome pathway.
Topics: Adverse Outcome Pathways; Animals; Brain; Female; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Ne | 2020 |
Stimulant Use in Pregnancy: An Under-recognized Epidemic Among Pregnant Women.
Topics: Alkaloids; Central Nervous System Stimulants; Cocaine; Female; Humans; Methamphetamine; N-Methyl-3,4 | 2019 |
Sources of variation in the design of preclinical studies assessing the effects of amphetamine-type stimulants in pregnancy and lactation.
Topics: Amphetamine; Amphetamines; Animals; Animals, Newborn; Central Nervous System Stimulants; Disease Mod | 2015 |
Abuse of amphetamines and structural abnormalities in the brain.
Topics: Abnormalities, Drug-Induced; Adult; Amphetamine-Related Disorders; Amphetamines; Animals; Attention | 2008 |
Developmental effects of 3,4-methylenedioxymethamphetamine: a review.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Female; Hallucinogens; Learning; Memory; N-Methyl-3,4 | 2008 |
18 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice.
Topics: Age Factors; Animals; Brain; Calcium-Binding Proteins; Dexamethasone; Disease Models, Animal; Diseas | 2021 |
Sex differences in the strategies of spatial learning in prenatally-exposed rats treated with various drugs in adulthood.
Topics: Animals; Cocaine; Cognition; Dronabinol; Female; Male; Methamphetamine; Morphine; N-Methyl-3,4-methy | 2017 |
Maternal MDMA administration in mice leads to neonatal growth delay.
Topics: Animals; Behavior, Animal; Body Weight; Female; Gestational Age; Growth and Development; Illicit Dru | 2014 |
Prenatal exposure to alcohol and 3,4-methylenedioxymethamphetamine (ecstasy) alters adult hippocampal neurogenesis and causes enduring memory deficits.
Topics: Animals; Behavior, Animal; Doublecortin Protein; Ethanol; Exploratory Behavior; Female; Hippocampus; | 2014 |
Developmental outcomes of 3,4-methylenedioxymethamphetamine (ecstasy)-exposed infants in the UK.
Topics: Adult; Age Factors; Child Development; Developmental Disabilities; Female; Hallucinogens; Humans; In | 2015 |
How various drugs affect anxiety-related behavior in male and female rats prenatally exposed to methamphetamine.
Topics: Analgesics; Analysis of Variance; Animals; Anxiety; Central Nervous System Stimulants; Estrous Cycle | 2016 |
Developmental exposure to 3,4-methylenedioxymethamphetamine results in downregulation of neurogenesis in the adult mouse hippocampus.
Topics: Animals; Antimetabolites; Astrocytes; Birth Weight; Bromodeoxyuridine; Cell Count; Cell Proliferatio | 2008 |
Long-term behavioral consequences of prenatal MDMA exposure.
Topics: Analysis of Variance; Animals; Association Learning; Attention; Behavior, Animal; Cocaine; Critical | 2009 |
Unsuspected exposure to cocaine in preschool children from a Mediterranean city detected by hair analysis.
Topics: Amphetamines; Cannabis; Child; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; | 2009 |
Intermittent prenatal MDMA exposure alters physiological but not mood related parameters in adult rat offspring.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Behavior, Animal; Blood Glucose; Body Weight; Corpus | 2010 |
Identification of post-generation effect of 3,4-methylenedioxymethamphetamine on the mouse brain by large-scale gene expression analysis.
Topics: Animals; Brain; Female; Gene Expression Profiling; Gene Expression Regulation; Male; Mice; Mice, Inb | 2010 |
MDMA (ecstasy) delays pubertal development and alters sperm quality after developmental exposure in the rat.
Topics: Animals; Female; Fertility; Hallucinogens; Hypothalamo-Hypophyseal System; Lactation; Male; N-Methyl | 2010 |
One-year outcomes of prenatal exposure to MDMA and other recreational drugs.
Topics: Cognition; Developmental Disabilities; Dose-Response Relationship, Drug; Female; Hallucinogens; Huma | 2012 |
Do prenatally methamphetamine-exposed adult male rats display general predisposition to drug abuse in the conditioned place preference test?
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Psychologic | 2012 |
Behavioral and antinociceptive effects of different psychostimulant drugs in prenatally methamphetamine-exposed rats.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Female; Male; Me | 2012 |
Functional consequences of perinatal exposure to 3,4-methylenedioxymethamphetamine in rat brain.
Topics: Adrenergic Uptake Inhibitors; Animals; Animals, Newborn; Binding, Competitive; Brain; Female; Glucos | 2002 |
Prenatal stress affects 3,4-methylenedioxymethamphetamine pharmacokinetics and drug-induced motor alterations in adolescent female rats.
Topics: Animals; Female; Hallucinogens; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Pregnancy; P | 2004 |
Effects of designer drugs on the chicken embryo and 1-day-old chicken.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Animals, Newborn; Body Weight; Chick Embryo; Chickens; Desig | 1994 |