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n-methyl-3,4-methylenedioxyamphetamine and Degenerative Diseases, Central Nervous System

n-methyl-3,4-methylenedioxyamphetamine has been researched along with Degenerative Diseases, Central Nervous System in 8 studies

N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Geng, X1
Li, S1
Li, J1
Qi, R1
Zhong, L1
Yu, H1
Costa, G1
Porceddu, PF1
Serra, M1
Casu, MA1
Schiano, V1
Napolitano, F1
Pinna, A1
Usiello, A1
Morelli, M1
Bissette, G1
Green, AR4
Mechan, AO1
Elliott, JM1
O'Shea, E4
Colado, MI3
Cadet, JL1
Brannock, C1
Granados, R1
Esteban, B2
Martín, AB1
Easton, N1
Fry, JR1
Marsden, CA1

Reviews

3 reviews available for n-methyl-3,4-methylenedioxyamphetamine and Degenerative Diseases, Central Nervous System

ArticleYear
Does Alzheimer's disease result from attempts at repair or protection after transient stress?
    Journal of Alzheimer's disease : JAD, 2009, Volume: 18, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Craniocerebral Tr

2009
The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy").
    Pharmacological reviews, 2003, Volume: 55, Issue:3

    Topics: Animals; Behavior, Animal; Body Temperature; Brain; Dopamine; Free Radicals; Hallucinogens; Humans;

2003
Free radicals and the pathobiology of brain dopamine systems.
    Neurochemistry international, 1998, Volume: 32, Issue:2

    Topics: Animals; Brain; Dopamine; Free Radicals; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyampheta

1998

Other Studies

5 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Degenerative Diseases, Central Nervous System

ArticleYear
MDMA targets miR-124/MEKK3 via MALAT1 to promote Parkinson's disease progression.
    Molecular biology reports, 2023, Volume: 50, Issue:11

    Topics: Animals; Apoptosis; Cell Line, Tumor; Disease Progression; Dopaminergic Neurons; Humans; MicroRNAs;

2023
Lack of Rhes Increases MDMA-Induced Neuroinflammation and Dopamine Neuron Degeneration: Role of Gender and Age.
    International journal of molecular sciences, 2019, Mar-28, Volume: 20, Issue:7

    Topics: Age Factors; Animals; Dopaminergic Neurons; Female; Gene Deletion; GTP-Binding Proteins; Hallucinoge

2019
Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy') administration.
    British journal of pharmacology, 1999, Volume: 126, Issue:4

    Topics: Animals; Body Temperature; Brain; Dopamine; Free Radicals; Haloperidol; Levodopa; Male; N-Methyl-3,4

1999
Studies on the neuroprotective effect of the enantiomers of AR-A008055, a compound structurally related to clomethiazole, on MDMA ("ecstasy")-induced neurodegeneration in rat brain.
    Psychopharmacology, 2001, Volume: 157, Issue:1

    Topics: Animals; Body Temperature; Chlormethiazole; Male; Methylamines; N-Methyl-3,4-methylenedioxyamphetami

2001
Protection against 3,4-methylenedioxymethamphetamine-induced neurodegeneration produced by glutathione depletion in rats is mediated by attenuation of hyperthermia.
    Journal of neurochemistry, 2002, Volume: 81, Issue:4

    Topics: Animals; Brain; Brain Chemistry; Buthionine Sulfoximine; Drug Therapy, Combination; Fever; Glutathio

2002