Page last updated: 2024-10-21

n-methyl-3,4-methylenedioxyamphetamine and Chronic Disease

n-methyl-3,4-methylenedioxyamphetamine has been researched along with Chronic Disease in 18 studies

N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"Chronic effects of MDMA abuse on seizure threshold have not been explored in detail so far."2.43MDMA and seizures: a dangerous liaison? ( Fornai, F; Giorgi, FS; Iudice, A; Lazzeri, G; Murri, L; Natale, G; Paparelli, A; Ruggieri, S, 2006)
" However, reports of adverse effects and fatalities have increased in the medical and popular press."2.41Agony and ecstasy: a review of MDMA effects and toxicity. ( Burgess, C; Gill, M; O'Donohoe, A, 2000)
"Chronic posttraumatic stress disorder (PTSD) is a disabling condition that generates considerable morbidity, mortality, and both medical and indirect social costs."1.56The cost-effectiveness of MDMA-assisted psychotherapy for the treatment of chronic, treatment-resistant PTSD. ( Doblin, R; Kahn, JG; Marseille, E; Yazar-Klosinski, B, 2020)
"We report a case of neurogenic bladder and chronic urinary retention associated with MDMA abuse."1.35Neurogenic bladder and chronic urinary retention associated with MDMA abuse. ( Barrueto, F; Beuerle, JR, 2008)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.11)18.2507
2000's11 (61.11)29.6817
2010's3 (16.67)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Greif, A1
Šurkala, M1
Marseille, E1
Kahn, JG1
Yazar-Klosinski, B1
Doblin, R2
Wunderli, MD1
Vonmoos, M1
Fürst, M1
Schädelin, K1
Kraemer, T1
Baumgartner, MR1
Seifritz, E1
Quednow, BB1
Beuerle, JR1
Barrueto, F1
Bouso, JC1
Farré, M1
Alcázar, MA1
Gómez-Jarabo, G1
León, LA1
Landeira-Fernandez, J1
Cardenas, FP1
Kish, SJ2
Lerch, J1
Furukawa, Y1
Tong, J1
McCluskey, T1
Wilkins, D1
Houle, S1
Meyer, J1
Mundo, E1
Wilson, AA1
Rusjan, PM1
Saint-Cyr, JA1
Guttman, M1
Collins, DL1
Shapiro, C1
Warsh, JJ1
Boileau, I1
Halpern, JH1
Sherwood, AR1
Hudson, JI1
Gruber, S1
Kozin, D1
Pope, HG1
Clatts, MC1
Goldsamt, LA1
Yi, H1
Dafters, RI1
Outslay, MG1
Giorgi, FS1
Lazzeri, G1
Natale, G1
Iudice, A1
Ruggieri, S1
Paparelli, A1
Murri, L1
Fornai, F1
Green, AR1
Goodwin, GM1
McGuire, P1
Burgess, C1
O'Donohoe, A1
Gill, M1
Rogers, RD1
Robbins, TW1
Schifano, F1

Reviews

7 reviews available for n-methyl-3,4-methylenedioxyamphetamine and Chronic Disease

ArticleYear
Compassionate use of psychedelics.
    Medicine, health care, and philosophy, 2020, Volume: 23, Issue:3

    Topics: Chronic Disease; Compassionate Use Trials; Hallucinogens; Humans; Mental Disorders; N-Methyl-3,4-met

2020
Understanding ecstasy.
    JAAPA : official journal of the American Academy of Physician Assistants, 2006, Volume: 19, Issue:7

    Topics: Acute Disease; Amphetamine-Related Disorders; Central Nervous System Stimulants; Chronic Disease; Co

2006
MDMA and seizures: a dangerous liaison?
    Annals of the New York Academy of Sciences, 2006, Volume: 1074

    Topics: Acute Disease; Animals; Chronic Disease; Disease Susceptibility; Drug Interactions; Hallucinogens; K

2006
Long term psychiatric and cognitive effects of MDMA use.
    Toxicology letters, 2000, Mar-15, Volume: 112-113

    Topics: Chronic Disease; Cognition Disorders; Hallucinogens; Humans; Memory Disorders; Mental Recall; N-Meth

2000
Agony and ecstasy: a review of MDMA effects and toxicity.
    European psychiatry : the journal of the Association of European Psychiatrists, 2000, Volume: 15, Issue:5

    Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Chronic Disease; Fever; Hallucinogens; Humans; Hyponat

2000
Investigating the neurocognitive deficits associated with chronic drug misuse.
    Current opinion in neurobiology, 2001, Volume: 11, Issue:2

    Topics: Animals; Chronic Disease; Cocaine-Related Disorders; Cognition Disorders; Humans; Marijuana Abuse; N

2001
How strong is the evidence that brain serotonin neurons are damaged in human users of ecstasy?
    Pharmacology, biochemistry, and behavior, 2002, Volume: 71, Issue:4

    Topics: Brain; Brain Chemistry; Chronic Disease; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetami

2002

Trials

1 trial available for n-methyl-3,4-methylenedioxyamphetamine and Chronic Disease

ArticleYear
MDMA-assisted psychotherapy using low doses in a small sample of women with chronic posttraumatic stress disorder.
    Journal of psychoactive drugs, 2008, Volume: 40, Issue:3

    Topics: Adult; Chronic Disease; Combined Modality Therapy; Dose-Response Relationship, Drug; Double-Blind Me

2008

Other Studies

10 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Chronic Disease

ArticleYear
The cost-effectiveness of MDMA-assisted psychotherapy for the treatment of chronic, treatment-resistant PTSD.
    PloS one, 2020, Volume: 15, Issue:10

    Topics: Adult; Chronic Disease; Clinical Trials, Phase II as Topic; Cost-Benefit Analysis; Double-Blind Meth

2020
Discrete memory impairments in largely pure chronic users of MDMA.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2017, Volume: 27, Issue:10

    Topics: Adult; Amphetamine-Related Disorders; Chronic Disease; Comorbidity; Female; Hair; Hallucinogens; Hum

2017
Neurogenic bladder and chronic urinary retention associated with MDMA abuse.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2008, Volume: 4, Issue:2

    Topics: Adult; Amphetamine-Related Disorders; Anti-Infective Agents, Urinary; Bethanechol; Central Nervous S

2008
Effects of chronic intracerebroventricular 3,4-methylenedioxy-N-methamphetamine (MDMA) or fluoxetine on the active avoidance test in rats with or without exposure to mild chronic stress.
    Behavioural brain research, 2009, Dec-14, Volume: 205, Issue:1

    Topics: Analysis of Variance; Animals; Avoidance Learning; Chronic Disease; Depression; Disease Models, Anim

2009
Decreased cerebral cortical serotonin transporter binding in ecstasy users: a positron emission tomography/[(11)C]DASB and structural brain imaging study.
    Brain : a journal of neurology, 2010, Volume: 133, Issue:Pt 6

    Topics: Adult; Amphetamine-Related Disorders; Benzylamines; Brain; Carbon Radioisotopes; Cerebral Cortex; Ch

2010
Residual neurocognitive features of long-term ecstasy users with minimal exposure to other drugs.
    Addiction (Abingdon, England), 2011, Volume: 106, Issue:4

    Topics: Adolescent; Adult; Case-Control Studies; Chronic Disease; Cognition; Cognition Disorders; Confoundin

2011
Club drug use among young men who have sex with men in NYC: a preliminary epidemiological profile.
    Substance use & misuse, 2005, Volume: 40, Issue:9-10

    Topics: Adolescent; Adult; Anesthetics, Dissociative; Central Nervous System Stimulants; Chronic Disease; Cr

2005
Chronic ecstasy (MDMA) use is associated with deficits in task-switching but not inhibition or memory updating executive functions.
    Drug and alcohol dependence, 2006, Jun-28, Volume: 83, Issue:2

    Topics: Adult; Chronic Disease; Cognition Disorders; Female; Humans; Inhibition, Psychological; Male; Memory

2006
Ecstasy and neurodegeneration.
    BMJ (Clinical research ed.), 1996, Jun-15, Volume: 312, Issue:7045

    Topics: Brain Diseases; Chronic Disease; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Nerv

1996
Chronic atypical psychosis associated with MDMA ("ecstasy") abuse.
    Lancet (London, England), 1991, Nov-23, Volume: 338, Issue:8778

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Chronic Disease; Humans; Male; N-Methyl-3,4-methylenedioxyamph

1991