Page last updated: 2024-10-21

n-methyl-3,4-methylenedioxyamphetamine and Bruxism

n-methyl-3,4-methylenedioxyamphetamine has been researched along with Bruxism in 7 studies

N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.

Bruxism: A disorder characterized by grinding and clenching of the teeth.

Research Excerpts

ExcerptRelevanceReference
"Oral effects include xerostomia, bruxism, and an increased risk of developing dental erosion."2.44Ecstasy (MDMA) and oral health. ( Brand, HS; Dun, SN; Nieuw Amerongen, AV, 2008)
"Bruxism is a recognized side effect of several licit and illicit drugs."1.36Bruxism after 3,4-methylenedioxymethamphetamine (ecstasy) abuse. ( Caldas, I; Carvalho, F; Dinis-Oliveira, RJ; Magalhães, T, 2010)
"All (119) subjects were poly-drug abusers (abused one or more illicit drugs in the past)."1.33Oral health sensations associated with illicit drug abuse. ( Chan, B; McGrath, C, 2005)
"It has been suggested that during bruxism a reduction of the activity of oral protective reflexes occurs."1.32Effects of 3,4-methylenedioxymethamphetamine ('Ecstasy') on the jaw-opening reflex and on the alpha-adrenoceptors which regulate this reflex in the anesthetized rat. ( Arrue, A; Giralt, MT; Gómez, FM, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's5 (71.43)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wood, DM1
Button, J1
Lidder, S1
Ramsey, J1
Holt, DW1
Dargan, PI1
Dinis-Oliveira, RJ1
Caldas, I1
Carvalho, F1
Magalhães, T1
Arrue, A1
Gómez, FM1
Giralt, MT1
McGrath, C1
Chan, B1
Brand, HS2
Dun, SN2
van Nieuw Amerongen, A1
Nieuw Amerongen, AV1
Vollenweider, FX1
Gamma, A1
Liechti, M1
Huber, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of MDMA on Prefrontal and Amygdala Activation in Posttraumatic Stress Disorder[NCT03752918]Phase 120 participants (Anticipated)Interventional2024-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for n-methyl-3,4-methylenedioxyamphetamine and Bruxism

ArticleYear
[Ecstasy use and oral health].
    Nederlands tijdschrift voor tandheelkunde, 2007, Volume: 114, Issue:2

    Topics: Bruxism; Humans; Mouth Mucosa; N-Methyl-3,4-methylenedioxyamphetamine; Oral Health; Saliva; Selectiv

2007
Ecstasy (MDMA) and oral health.
    British dental journal, 2008, Jan-26, Volume: 204, Issue:2

    Topics: Adult; Animals; Bruxism; Dental Care for Chronically Ill; Hallucinogens; Humans; N-Methyl-3,4-methyl

2008

Trials

1 trial available for n-methyl-3,4-methylenedioxyamphetamine and Bruxism

ArticleYear
Psychological and cardiovascular effects and short-term sequelae of MDMA ("ecstasy") in MDMA-naïve healthy volunteers.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1998, Volume: 19, Issue:4

    Topics: Adult; Affect; Anorexia; Blood Pressure; Body Temperature; Bruxism; Double-Blind Method; Fatigue; Fe

1998

Other Studies

4 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Bruxism

ArticleYear
Dissociative and sympathomimetic toxicity associated with recreational use of 1-(3-trifluoromethylphenyl) piperazine (TFMPP) and 1-benzylpiperzine (BZP).
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2008, Volume: 4, Issue:4

    Topics: Adolescent; Bruxism; Dissociative Disorders; Electrocardiography; Gas Chromatography-Mass Spectromet

2008
Bruxism after 3,4-methylenedioxymethamphetamine (ecstasy) abuse.
    Clinical toxicology (Philadelphia, Pa.), 2010, Volume: 48, Issue:8

    Topics: Bruxism; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin; Serotonin Agents; Substance-Rela

2010
Effects of 3,4-methylenedioxymethamphetamine ('Ecstasy') on the jaw-opening reflex and on the alpha-adrenoceptors which regulate this reflex in the anesthetized rat.
    European journal of oral sciences, 2004, Volume: 112, Issue:2

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; An

2004
Oral health sensations associated with illicit drug abuse.
    British dental journal, 2005, Feb-12, Volume: 198, Issue:3

    Topics: Adolescent; Adult; Bruxism; Facial Pain; Female; Hong Kong; Humans; Male; Mouth Diseases; N-Methyl-3

2005