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n-methyl-3,4-methylenedioxyamphetamine and Brain Swelling

n-methyl-3,4-methylenedioxyamphetamine has been researched along with Brain Swelling in 22 studies

N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
" We report a case of combined ecstasy/cocaine-induced fulminant hepatic failure presenting with severe rhabdomyolysis, myocardial infarction and multiorgan failure."3.72Successful treatment of refractory cerebral oedema in ecstasy/cocaine-induced fulminant hepatic failure using a new high-efficacy liver detoxification device (FPSA-Prometheus). ( Bauer, E; Kramer, L; Mallek, R; Schenk, P; Steininger, R; Vigl, M, 2003)
" While it is known that their abuse could result in adverse health complications, including neurotoxicity, both the environmental conditions and activity states associated with their intake could strongly enhance drug toxicity, often resulting in life-threatening health complications."2.48Environmental conditions modulate neurotoxic effects of psychomotor stimulant drugs of abuse. ( Kiyatkin, EA; Sharma, HS, 2012)
"She died of water intoxication and cerebral edema approximately 24 hours after ingestion of one tablet of "ecstasy" at a rave club in Amsterdam."1.31[Young woman dies of water intoxication after taking one tablet of ecstasy. Today's drug panorama calls for increased vigilance in health care]. ( Bråbäck, L; Humble, M, 2001)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (27.27)18.2507
2000's9 (40.91)29.6817
2010's7 (31.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pérez-Hernández, M1
Fernández-Valle, ME1
Rubio-Araiz, A1
Vidal, R1
Gutiérrez-López, MD1
O'Shea, E1
Colado, MI1
Ligtenberg, JJ1
Olgers, TJ1
van de Meeberg, EK1
ter Maaten, JC1
Baumann, S1
Becher, T1
Frambach, D1
Wenz, H1
Kirschning, T1
Borggrefe, M1
Rapp, S1
Akin, I1
Sharma, HS2
Ali, SF1
Tóth, AR1
Varga, T1
Ghatol, A1
Kazory, A1
Lusthof, KJ1
Oosting, R1
Maes, A1
Verschraagen, M1
Dijkhuizen, A1
Sprong, AG1
Claffey, C1
Kiyatkin, EA1
Hughes, RD1
Kramer, L1
Bauer, E1
Schenk, P1
Steininger, R1
Vigl, M1
Mallek, R1
Morán Chorro, I1
Marruecos Sant, L1
Delgado Martín, MO1
Libiseller, K1
Pavlic, M1
Grubwieser, P1
Rabl, W1
Sauvageau, A1
Matthai, SM1
Davidson, DC1
Sills, JA1
Alexandrou, D1
Cook, TM1
Wilkins, B1
Finch, E1
Sell, L1
Arnold, D1
Parr, MJ1
Low, HM1
Botterill, P1
O'Connor, A1
Cluroe, A1
Couch, R1
Galler, L1
Lawrence, J1
Synek, B1
Bråbäck, L1
Humble, M1
Balmelli, C1
Kupferschmidt, H1
Rentsch, K1
Schneemann, M1

Reviews

1 review available for n-methyl-3,4-methylenedioxyamphetamine and Brain Swelling

ArticleYear
Environmental conditions modulate neurotoxic effects of psychomotor stimulant drugs of abuse.
    International review of neurobiology, 2012, Volume: 102

    Topics: Animals; Blood-Brain Barrier; Body Temperature; Brain; Brain Edema; Environment; Fever; Hot Temperat

2012

Other Studies

21 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Brain Swelling

ArticleYear
3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) produces edema due to BBB disruption induced by MMP-9 activation in rat hippocampus.
    Neuropharmacology, 2017, 05-15, Volume: 118

    Topics: Animals; Aquaporin 4; Blood-Brain Barrier; Brain Edema; Claudin-5; Disease Models, Animal; Enzyme In

2017
Re: MDMA-associated cerebral edema resembling psychogenic polydipsia?
    The Journal of emergency medicine, 2015, Volume: 48, Issue:1

    Topics: Brain Edema; Diuretics, Osmotic; Female; Hallucinogens; Humans; Hyponatremia; Mannitol; N-Methyl-3,4

2015
[Hyponatremia-induced life-threatening cerebral edema after ecstasy use].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2016, Volume: 111, Issue:6

    Topics: Brain Edema; Hallucinogens; Humans; Hyponatremia; N-Methyl-3,4-methylenedioxyamphetamine; Sodium; Yo

2016
Acute administration of 3,4-methylenedioxymethamphetamine induces profound hyperthermia, blood-brain barrier disruption, brain edema formation, and cell injury.
    Annals of the New York Academy of Sciences, 2008, Volume: 1139

    Topics: Albumins; Animals; Astrocytes; Behavior, Animal; Blood-Brain Barrier; Body Temperature; Brain Edema;

2008
Myocardium and striated muscle damage caused by licit or illicit drugs.
    Legal medicine (Tokyo, Japan), 2009, Volume: 11 Suppl 1

    Topics: Adolescent; Adult; Alprazolam; Anticonvulsants; Brain Edema; Clonazepam; Creatine Kinase; Female; Fe

2009
Ecstasy-associated acute severe hyponatremia and cerebral edema: a role for osmotic diuresis?
    The Journal of emergency medicine, 2012, Volume: 42, Issue:6

    Topics: Acute Disease; Brain Edema; Diuresis; Diuretics, Osmotic; Female; Hallucinogens; Humans; Hyponatremi

2012
A case of extreme agitation and death after the use of mephedrone in The Netherlands.
    Forensic science international, 2011, Mar-20, Volume: 206, Issue:1-3

    Topics: Adult; Brain Edema; Central Nervous System Stimulants; Cocaine; Contusions; Delirium; Designer Drugs

2011
A 26-year-old woman with sudden onset cerebral edema.
    Journal of emergency nursing, 2011, Volume: 37, Issue:1

    Topics: Acute Disease; Adult; Brain Edema; Confusion; Diuretics, Osmotic; Emergency Treatment; Fatal Outcome

2011
Liver support in acute liver failure.
    Wiener klinische Wochenschrift, 2003, Sep-15, Volume: 115, Issue:15-16

    Topics: Acute Disease; Brain Edema; Clinical Trials as Topic; Cocaine; Critical Care; Dialysis; Hemoperfusio

2003
Successful treatment of refractory cerebral oedema in ecstasy/cocaine-induced fulminant hepatic failure using a new high-efficacy liver detoxification device (FPSA-Prometheus).
    Wiener klinische Wochenschrift, 2003, Sep-15, Volume: 115, Issue:15-16

    Topics: Adult; Ammonia; Brain Edema; Cocaine; Encephalocele; Follow-Up Studies; Hepatic Encephalopathy; Huma

2003
[Hyponatremia, cerebral edema and brain death in a MDMA acute intoxication].
    Medicina clinica, 2005, Feb-12, Volume: 124, Issue:5

    Topics: Adult; Amphetamine-Related Disorders; Brain Death; Brain Edema; Fatal Outcome; Female; Hallucinogens

2005
Ecstasy--deadly risk even outside rave parties.
    Forensic science international, 2005, Oct-29, Volume: 153, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Asphyxia; Brain Edema; Cannabinoids; Female; Forensic Medicine

2005
Death from a possible anaphylactic reaction to ecstasy.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:2

    Topics: Adolescent; Anaphylaxis; Autopsy; Brain Edema; Emergency Service, Hospital; Fatal Outcome; Female; H

2008
Cerebral oedema after ingestion of MDMA ("ecstasy") and unrestricted intake of water.
    BMJ (Clinical research ed.), 1996, May-25, Volume: 312, Issue:7042

    Topics: Adolescent; Brain Edema; Drinking; Female; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyampheta

1996
Cerebral oedema after MDMA ("ecstasy") and unrestricted water intake. Values for plasma osmolality may have been wrong.
    BMJ (Clinical research ed.), 1996, Sep-14, Volume: 313, Issue:7058

    Topics: Brain Edema; Drinking; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Osmolar Concen

1996
Cerebral oedema after MDMA ("ecstasy") and unrestricted water intake. Hyponatraemia must be treated with low water input.
    BMJ (Clinical research ed.), 1996, Sep-14, Volume: 313, Issue:7058

    Topics: Brain Edema; Drinking; Hallucinogens; Humans; Hyponatremia; N-Methyl-3,4-methylenedioxyamphetamine;

1996
Cerebral oedema after MDMA ("ecstasy") and unrestricted water intake. Drug workers emphasise that water is not an antidote to drug.
    BMJ (Clinical research ed.), 1996, Sep-14, Volume: 313, Issue:7058

    Topics: Antidotes; Brain Edema; Drinking; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Wat

1996
Hyponatraemia and death after "ecstasy" ingestion.
    The Medical journal of Australia, 1997, Feb-03, Volume: 166, Issue:3

    Topics: Adolescent; Brain Death; Brain Edema; Drug Overdose; Fatal Outcome; Female; Glasgow Coma Scale; Hall

1997
Death from hyponatraemia-induced cerebral oedema associated with MDMA ("Ecstasy") use.
    The New Zealand medical journal, 1999, Jul-09, Volume: 112, Issue:1091

    Topics: Adult; Brain Edema; Drug Overdose; Fatal Outcome; Female; Hallucinogens; Humans; Hyponatremia; N-Met

1999
[Young woman dies of water intoxication after taking one tablet of ecstasy. Today's drug panorama calls for increased vigilance in health care].
    Lakartidningen, 2001, Feb-21, Volume: 98, Issue:8

    Topics: Adult; Brain Edema; Cause of Death; Fatal Outcome; Female; Heart Failure; Humans; Illicit Drugs; Ina

2001
[Fatal brain edema after ingestion of ecstasy and benzylpiperazine].
    Deutsche medizinische Wochenschrift (1946), 2001, Jul-13, Volume: 126, Issue:28-29

    Topics: Adult; Brain Edema; Fatal Outcome; Female; Hallucinogens; Humans; Hyponatremia; Illicit Drugs; N-Met

2001