Page last updated: 2024-10-21

n-methyl-3,4-methylenedioxyamphetamine and Astrocytosis

n-methyl-3,4-methylenedioxyamphetamine has been researched along with Astrocytosis in 5 studies

N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Kainic acid (KA) causes seizures and neuronal loss in the hippocampus."3.803,4-Methylenedioxymethamphetamine enhances kainic acid convulsive susceptibility. ( Abad, S; Auladell, C; Camarasa, J; Camins, A; Escubedo, E; Junyent, F; Pallàs, M; Pubill, D, 2014)
"They also prevent METH-induced reactive gliosis in dopaminergic cultures."1.29Involvement of oxidative and L-arginine-NO pathways in the neurotoxicity of drugs of abuse in vitro. ( Cadet, JL; Cerruti, C; Epstein, CJ; Ladenheim, B; Sheng, P, 1995)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Costa, G2
Serra, M1
Maccioni, R1
Casu, MA2
Kasture, SB1
Acquas, E1
Morelli, M2
Spulber, S1
Paci, E1
Ceccatelli, S1
Simola, N1
Abad, S1
Junyent, F1
Auladell, C1
Pubill, D1
Pallàs, M1
Camarasa, J1
Escubedo, E1
Camins, A1
Miner, NB1
O'Callaghan, JP1
Phillips, TJ1
Janowsky, A1
Cerruti, C1
Sheng, P1
Ladenheim, B1
Epstein, CJ1
Cadet, JL1

Other Studies

5 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Astrocytosis

ArticleYear
Withania somnifera influences MDMA-induced hyperthermic, cognitive, neurotoxic and neuroinflammatory effects in mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 161

    Topics: Animals; Cognition; Gliosis; Hyperthermia, Induced; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Ne

2023
In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice.
    Neurotoxicology, 2021, Volume: 83

    Topics: Age Factors; Animals; Brain; Calcium-Binding Proteins; Dexamethasone; Disease Models, Animal; Diseas

2021
3,4-Methylenedioxymethamphetamine enhances kainic acid convulsive susceptibility.
    Progress in neuro-psychopharmacology & biological psychiatry, 2014, Oct-03, Volume: 54

    Topics: Animals; Astrocytes; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Convulsants; Dose-Respon

2014
The combined effects of 3,4-methylenedioxymethamphetamine (MDMA) and selected substituted methcathinones on measures of neurotoxicity.
    Neurotoxicology and teratology, 2017, Volume: 61

    Topics: Animals; Benzodioxoles; Body Temperature Regulation; Corpus Striatum; Dopamine; Glial Fibrillary Aci

2017
Involvement of oxidative and L-arginine-NO pathways in the neurotoxicity of drugs of abuse in vitro.
    Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:5

    Topics: Adenosine Diphosphate Ribose; Animals; Arginine; Brain; Cell Death; Cells, Cultured; Dopamine; Dopam

1995