n-methyl-3,4-methylenedioxyamphetamine has been researched along with Anesthesia Related Hyperthermia in 10 studies
N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dantrolene is a skeletal muscle relaxant that depresses the excitation-contraction coupling,however, the specificity of action remains unknown." | 2.42 | [Dantrolene. Pharmacological and therapeutic aspects]. ( Agarwal, K; Fiege, M; Gerbershagen, MU; Krause, T; Wappler, F, 2003) |
| "After achieving predefined malignant hyperthermia criteria, standardised therapy was initiated; dantrolene sodium suspension (5 mg kg(-1)) was administered and the injection was repeated after 24 min." | 1.39 | 3,4-Methylenedioxymethamphetamine induces a hyperthermic and hypermetabolic crisis in pigs with and without a genetic disposition for malignant hyperthermia. ( Becker, S; Gerbershagen, MU; Oldewurtel, C; Richard, A; Schäfer, U; Schütte, JK; Singler, P; Starosse, A; Wappler, F, 2013) |
| "Consequently, the malignant hyperthermia status should not affect the calcium sensitivity of the contractile apparatus." | 1.38 | 3,4-Methylenedioxymethamphetamine (Ecstasy) increases the sensitivity of the contractile apparatus to calcium ions in both malignant hyperthermia-susceptible and normal skeletal muscle fibres. ( Gerbershagen, MU; Graf, BM; Missler, G; Schütte, JK; Starosse, A; Wappler, F; Zink, W, 2012) |
| " The left-shift of the dose-response curve induced by MDMA was greater in normal than in MHS muscle." | 1.33 | 3,4-Methylenedioxymethamphetamine (ecstasy) activates skeletal muscle nicotinic acetylcholine receptors. ( Alt, A; Bufler, J; Heffron, JJ; Jurkat-Rott, K; Klingler, W; Lehmann-Horn, F; O'sullivan, G; Schlesinger, F, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gerbershagen, MU | 4 |
| Missler, G | 1 |
| Schütte, JK | 2 |
| Starosse, A | 2 |
| Graf, BM | 1 |
| Wappler, F | 4 |
| Zink, W | 1 |
| Schäfer, U | 1 |
| Becker, S | 1 |
| Oldewurtel, C | 1 |
| Singler, P | 1 |
| Richard, A | 1 |
| Fiege, M | 2 |
| Krause, T | 1 |
| Agarwal, K | 1 |
| Weisshorn, R | 1 |
| Menge, M | 1 |
| Schulte Am Esch, J | 1 |
| Rusyniak, DE | 1 |
| Banks, ML | 1 |
| Mills, EM | 1 |
| Sprague, JE | 1 |
| Klingler, W | 1 |
| Heffron, JJ | 1 |
| Jurkat-Rott, K | 1 |
| O'sullivan, G | 1 |
| Alt, A | 1 |
| Schlesinger, F | 1 |
| Bufler, J | 1 |
| Lehmann-Horn, F | 1 |
| McCoy, EP | 1 |
| Renfrew, C | 1 |
| Johnston, JR | 1 |
| Lavery, G | 1 |
| Denborough, MA | 1 |
| Hopkinson, KC | 1 |
| Möller-Nehring, E | 1 |
| Luderer, HJ | 1 |
| O'Leary, G | 1 |
| Nargiso, J | 1 |
| Weiss, RD | 1 |
2 reviews available for n-methyl-3,4-methylenedioxyamphetamine and Anesthesia Related Hyperthermia
| Article | Year |
|---|---|
[Dantrolene. Pharmacological and therapeutic aspects].
Topics: Dantrolene; Drug Interactions; Hallucinogens; Humans; Malignant Hyperthermia; Muscle Relaxants, Cent | 2003 |
3,4-methylenedioxymethamphetamine (MDMA): a review.
Topics: Brain; Depression; Hallucinogens; Humans; Malignant Hyperthermia; N-Methyl-3,4-methylenedioxyampheta | 2001 |
8 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Anesthesia Related Hyperthermia
| Article | Year |
|---|---|
3,4-Methylenedioxymethamphetamine (Ecstasy) increases the sensitivity of the contractile apparatus to calcium ions in both malignant hyperthermia-susceptible and normal skeletal muscle fibres.
Topics: Animals; Calcium Signaling; Dose-Response Relationship, Drug; Malignant Hyperthermia; Muscle Contrac | 2012 |
3,4-Methylenedioxymethamphetamine induces a hyperthermic and hypermetabolic crisis in pigs with and without a genetic disposition for malignant hyperthermia.
Topics: Acidosis; Animals; Dantrolene; Fatty Acids, Nonesterified; Fever; Genetic Predisposition to Disease; | 2013 |
Induction of malignant hyperthermia in susceptible swine by 3,4-methylenedioxymethamphetamine ("ecstasy").
Topics: Animals; Blood Gas Analysis; Body Temperature; Carbon Dioxide; Dantrolene; Dose-Response Relationshi | 2003 |
Dantrolene use in 3,4-methylenedioxymethamphetamine (ecstasy)-mediated hyperthermia.
Topics: Animals; Body Temperature; Dantrolene; Disease Models, Animal; Hallucinogens; Malignant Hyperthermia | 2004 |
3,4-Methylenedioxymethamphetamine (ecstasy) activates skeletal muscle nicotinic acetylcholine receptors.
Topics: Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Malignant Hyperthermia; | 2005 |
Malignant hyperpyrexia in an MDMA ("Ecstasy") abuser.
Topics: Adult; Diagnosis, Differential; Hallucinogens; Humans; Male; Malignant Hyperthermia; N-Methyl-3,4-me | 1994 |
Dantrolene and "ecstasy".
Topics: Calcium; Dantrolene; Hallucinogens; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Cont | 1997 |
[Is the anxiety about Ecstasy justified?].
Topics: Adolescent; Adult; Animals; Brain; Cause of Death; Hallucinogens; Humans; Malignant Hyperthermia; N- | 1997 |