Compounds > n-methyl-3,4-methylenedioxyamphetamine
Page last updated: 2024-10-21

n-methyl-3,4-methylenedioxyamphetamine and Acute Disease

n-methyl-3,4-methylenedioxyamphetamine has been researched along with Acute Disease in 38 studies

N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
" Alcohol dosing was designed to achieve a peak blood alcohol concentration (BAC) of about 0."2.72Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on behavioral measures of impulsivity: alone and in combination with alcohol. ( Kuypers, KP; Ramaekers, JG, 2006)
"Chronic effects of MDMA abuse on seizure threshold have not been explored in detail so far."2.43MDMA and seizures: a dangerous liaison? ( Fornai, F; Giorgi, FS; Iudice, A; Lazzeri, G; Murri, L; Natale, G; Paparelli, A; Ruggieri, S, 2006)
" However, reports of adverse effects and fatalities have increased in the medical and popular press."2.41Agony and ecstasy: a review of MDMA effects and toxicity. ( Burgess, C; Gill, M; O'Donohoe, A, 2000)
"Her hyponatremia was slowly corrected."1.32Transient proximal tubular renal injury following Ecstasy ingestion. ( Dharnidharka, VR; Kwon, C; Zaritsky, A, 2003)
"We report the case of an acute cerebral hemorrhage after one "ecstasy" tablet in a 21 year old woman without any relevant medical or surgical history."1.30[Cerebral hemorrhage and "ecstasy"]. ( de Torrenté, A; Prica, A; Schlaeppi, M, 1999)
"An idiosyncratic toxic hepatitis might be due to either 3,4-methylenedioxymethylamphetamine or a metabolite, a contaminant in 3,4-methylenedioxymethylamphetamine manufacture, or to an additive in tablet or capsule formulation."1.29[Acute hepatitis due to ingestion of Ecstasy]. ( Huarte Muniesa, MP; Pueyo Royo, AM, 1995)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (31.58)18.2507
2000's22 (57.89)29.6817
2010's4 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Camilleri, R1
Fulde, GW1
Forster, SL1
Campbell, GA1
Rosner, MH1
Ghatol, A1
Kazory, A1
Claffey, C1
Masi, G1
Mucci, M1
Floriani, C1
Inman, DS1
Greene, D1
Kwon, C1
Zaritsky, A1
Dharnidharka, VR1
Hughes, RD1
Chishiro, T1
Matsubara, M1
Kiuchi, S1
Delgado, JH1
Caruso, MJ1
Waksman, JC1
Honigman, B1
Stillman, D1
Orio, L1
O'Shea, E2
Sanchez, V1
Pradillo, JM1
Escobedo, I1
Camarero, J1
Moro, MA1
Green, AR2
Colado, MI2
Cosentino, C1
Ramaekers, JG1
Kuypers, KP1
Goldstein, LH1
Mordish, Y1
Abu-Kishak, I1
Toledano, M1
Berkovitch, M1
Ferrington, L1
Kirilly, E1
McBean, DE1
Olverman, HJ1
Bagdy, G1
Kelly, PA1
Outslay, MG1
Chang, SH1
Lai, TI1
Chen, WJ1
Fang, CC1
Giorgi, FS1
Lazzeri, G1
Natale, G1
Iudice, A1
Ruggieri, S1
Paparelli, A1
Murri, L1
Fornai, F1
Moon, J1
Cros, J1
Riva, N1
Morana, P1
Cerri, F1
Gerevini, S1
Amadio, S1
Formaglio, F1
Comi, G1
Comola, M1
Del Carro, U1
Huarte Muniesa, MP1
Pueyo Royo, AM1
Steidle, B1
Klein, M1
Oranje, WA1
von Pol, P1
vd Wurff, A1
Zeijen, RN1
Stockbrügger, RW1
Arends, JW1
Bitsch, A1
Thiel, A1
Rieckmann, P1
Prange, H1
Montgomery, H1
Myerson, S1
Nakahara, Y1
Kikura, R1
Roques, V1
Perney, P1
Beaufort, P1
Hanslik, B1
Ramos, J1
Durand, L1
Le Bricquir, Y1
Blanc, F1
Indart Pérez, A1
Mendia Gorostidi, A1
Barrio Andrés, J1
Arens Miravé, I1
Schlaeppi, M1
Prica, A1
de Torrenté, A1
Burgess, C1
O'Donohoe, A1
Gill, M1
Trejo Gutiérrez, O1
Ortega Romero, M1
Perea Gainza, M1
Nogué Xarau, S1
Mechan, AO1
Esteban, B1
Elliott, JM1
Chaudier, B1
Oliver, M1
Coton, T1
Civatte, M1
Guisset, M1
Carré, D1
Debonne, JM1
Delpy, R1
Diaz, V1
Wyckoff, MM1
Gorard, DA1
Davies, SE1
Clark, ML1
Shearman, JD1
Chapman, RW1
Satsangi, J1
Ryley, NG1
Weatherhead, S1
Rittoo, D2
Rittoo, DB1

Reviews

9 reviews available for n-methyl-3,4-methylenedioxyamphetamine and Acute Disease

ArticleYear
A meta-analysis of the reliability of the history in suspected poisoning.
    The Journal of emergency medicine, 2015, Volume: 48, Issue:6

    Topics: Acetaminophen; Acute Disease; Cocaine; Drug Overdose; Humans; Medical History Taking; N-Methyl-3,4-m

2015
The impact of amphetamine-type stimulants on emergency services.
    Current opinion in psychiatry, 2015, Volume: 28, Issue:4

    Topics: Acute Disease; Aggression; Amphetamine; Amphetamine-Related Disorders; Anxiety; Central Nervous Syst

2015
The agony of ecstasy: MDMA (3,4-methylenedioxymethamphetamine) and the kidney.
    Clinical journal of the American Society of Nephrology : CJASN, 2008, Volume: 3, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Female; Hallucinogens; Humans; Hyponatremia; Kidney; Kidney Diseas

2008
Understanding ecstasy.
    JAAPA : official journal of the American Academy of Physician Assistants, 2006, Volume: 19, Issue:7

    Topics: Acute Disease; Amphetamine-Related Disorders; Central Nervous System Stimulants; Chronic Disease; Co

2006
MDMA and seizures: a dangerous liaison?
    Annals of the New York Academy of Sciences, 2006, Volume: 1074

    Topics: Acute Disease; Animals; Chronic Disease; Disease Susceptibility; Drug Interactions; Hallucinogens; K

2006
[Computed tomography in acute rhabdomyolysis].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1995, Volume: 163, Issue:4

    Topics: Acute Disease; Adult; Cocaine; Diagnosis, Differential; Diphenhydramine; Heroin Dependence; Humans;

1995
XTC-induced hepatitis.
    The Netherlands journal of medicine, 1994, Volume: 44, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adult; Biopsy; Chemical and Drug Induced Liver Injury;

1994
Agony and ecstasy: a review of MDMA effects and toxicity.
    European psychiatry : the journal of the Association of European Psychiatrists, 2000, Volume: 15, Issue:5

    Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Chronic Disease; Fever; Hallucinogens; Humans; Hyponat

2000
Surviving fulminant hepatic failure.
    The American journal of nursing, 2002, Volume: Suppl

    Topics: Acute Disease; Adolescent; Anuria; Critical Care; Diagnosis, Differential; Female; Graft Rejection;

2002

Trials

1 trial available for n-methyl-3,4-methylenedioxyamphetamine and Acute Disease

ArticleYear
Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on behavioral measures of impulsivity: alone and in combination with alcohol.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:5

    Topics: Acute Disease; Adult; Alcohol-Induced Disorders, Nervous System; Brain; Central Nervous System Depre

2006

Other Studies

28 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Acute Disease

ArticleYear
Ecstasy-associated acute severe hyponatremia and cerebral edema: a role for osmotic diuresis?
    The Journal of emergency medicine, 2012, Volume: 42, Issue:6

    Topics: Acute Disease; Brain Edema; Diuresis; Diuretics, Osmotic; Female; Hallucinogens; Humans; Hyponatremi

2012
A 26-year-old woman with sudden onset cerebral edema.
    Journal of emergency nursing, 2011, Volume: 37, Issue:1

    Topics: Acute Disease; Adult; Brain Edema; Confusion; Diuretics, Osmotic; Emergency Treatment; Fatal Outcome

2011
Acute catatonia after a single dose of ecstasy.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2002, Volume: 41, Issue:8

    Topics: Acute Disease; Adolescent; Catatonia; Clozapine; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamin

2002
The agony and the ecstasy: acute urinary retention after MDMA abuse.
    BJU international, 2003, Volume: 91, Issue:1

    Topics: Acute Disease; Adolescent; Hallucinogens; Humans; Illicit Drugs; Male; N-Methyl-3,4-methylenedioxyam

2003
Transient proximal tubular renal injury following Ecstasy ingestion.
    Pediatric nephrology (Berlin, Germany), 2003, Volume: 18, Issue:8

    Topics: Acute Disease; Adolescent; Female; Hallucinogens; Humans; Hyponatremia; Kidney Diseases; Kidney Tubu

2003
Liver support in acute liver failure.
    Wiener klinische Wochenschrift, 2003, Sep-15, Volume: 115, Issue:15-16

    Topics: Acute Disease; Brain Edema; Clinical Trials as Topic; Cocaine; Critical Care; Dialysis; Hemoperfusio

2003
[Two cases of "Ecstasy (MDMA)" poisoning].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2003, Volume: 16, Issue:4

    Topics: Acute Disease; Adult; Alcoholic Beverages; Charcoal; Crime; Female; Gastric Lavage; Hallucinogens; H

2003
Acute, transient urinary retention from combined ecstasy and methamphetamine use.
    The Journal of emergency medicine, 2004, Volume: 26, Issue:2

    Topics: Acute Disease; Adolescent; Alcohol Drinking; Amphetamine-Related Disorders; Emergency Medical Servic

2004
3,4-Methylenedioxymethamphetamine increases interleukin-1beta levels and activates microglia in rat brain: studies on the relationship with acute hyperthermia and 5-HT depletion.
    Journal of neurochemistry, 2004, Volume: 89, Issue:6

    Topics: Acute Disease; Animals; Astrocytes; Binding, Competitive; Body Temperature; Brain; Cerebral Cortex;

2004
Ecstasy and acute dystonia.
    Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:11

    Topics: Acute Disease; Adolescent; Adrenergic Uptake Inhibitors; Biperiden; Dose-Response Relationship, Drug

2004
Acute paralysis following recreational MDMA (Ecstasy) use.
    Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:3

    Topics: Acute Disease; Adolescent; Hallucinogens; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Quad

2006
Persistent cerebrovascular effects of MDMA and acute responses to the drug.
    The European journal of neuroscience, 2006, Volume: 24, Issue:2

    Topics: Acute Disease; Animals; Antipyrine; Autonomic Pathways; Carbon Radioisotopes; Cerebral Arteries; Cer

2006
MDMA-induced acute pulmonary edema in a patient without other organ dysfunction.
    The American journal of emergency medicine, 2006, Volume: 24, Issue:6

    Topics: Acute Disease; Adult; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Pulmonary Edema; Radiogr

2006
Role of dantrolene in the management of the acute toxic effects of Ecstasy (MDMA).
    British journal of anaesthesia, 2007, Volume: 99, Issue:1

    Topics: Acute Disease; Adult; Dantrolene; Fever; Hallucinogens; Humans; Male; Muscle Relaxants, Central; N-M

2007
Acute myelopathy selectively involving lumbar anterior horns following intranasal insufflation of ecstasy and heroin.
    Journal of neurology, neurosurgery, and psychiatry, 2007, Volume: 78, Issue:8

    Topics: Acute Disease; Administration, Inhalation; Adolescent; Drug Overdose; Female; Hallucinogens; Heroin;

2007
[Acute hepatitis due to ingestion of Ecstasy].
    Revista espanola de enfermedades digestivas, 1995, Volume: 87, Issue:9

    Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Follow-Up Studies; Hallucinogens; Huma

1995
Acute inflammatory CNS disease after MDMA ('ecstasy').
    European neurology, 1996, Volume: 36, Issue:5

    Topics: Acute Disease; Adult; Central Nervous System Diseases; Hallucinogens; Humans; Inflammation; Magnetic

1996
3,4-methylenedioxymethamphetamine (MDMA, or "ecstasy") and associated hypoglycemia.
    The American journal of emergency medicine, 1997, Volume: 15, Issue:2

    Topics: Acute Disease; Adult; Dantrolene; Female; Fever; Hallucinogens; Humans; Hypoglycemia; Muscle Relaxan

1997
Hair analysis for drugs of abuse. XVIII. 3,4-Methylenedioxymethamphetamine (MDMA) disposition in hair roots and use in identification of acute MDMA poisoning.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:9

    Topics: Acute Disease; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hair; Hallucinogen

1997
[Acute hepatitis due to ecstasy].
    Presse medicale (Paris, France : 1983), 1998, Mar-14, Volume: 27, Issue:10

    Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Hallucinogens; Humans; Jaundice; Liver

1998
[Acute hepatitis induced by Ecstasy].
    Gastroenterologia y hepatologia, 1998, Volume: 21, Issue:10

    Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Hallucinogens; Humans; Male; N-Methyl-

1998
[Cerebral hemorrhage and "ecstasy"].
    Praxis, 1999, Mar-25, Volume: 88, Issue:13

    Topics: Acute Disease; Adult; Cerebral Hemorrhage; Female; Follow-Up Studies; Hallucinogens; Humans; Magneti

1999
[Multiple organ failure associated with use of ecstasy].
    Revista clinica espanola, 2001, Volume: 201, Issue:2

    Topics: Acute Disease; Adolescent; Hallucinogens; Humans; Male; Multiple Organ Failure; N-Methyl-3,4-methyle

2001
The pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to rats.
    British journal of pharmacology, 2002, Volume: 135, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Animals; Benzazepines; Body Temperature; Corpus Striat

2002
[Chronic hepatitis with an acute presentation due to Ecstasy].
    Gastroenterologie clinique et biologique, 2002, Volume: 26, Issue:1

    Topics: Acute Disease; Adolescent; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver I

2002
Misuse of ecstasy.
    BMJ (Clinical research ed.), 1992, Aug-01, Volume: 305, Issue:6848

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Designe

1992
Misuse of ecstasy.
    BMJ (Clinical research ed.), 1992, Aug-01, Volume: 305, Issue:6848

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Designe

1992
Misuse of ecstasy.
    BMJ (Clinical research ed.), 1992, Aug-01, Volume: 305, Issue:6848

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adolescent; Chest Pain; Designer Drugs; Female; Humans

1992