n-methyl-3,4-methylenedioxyamphetamine has been researched along with Absence Seizure in 42 studies
N-Methyl-3,4-methylenedioxyamphetamine: An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.
3,4-methylenedioxymethamphetamine : A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty-four patients presenting with first-ever seizure within 24 h of illicit use of amphetamine or related analogs (amphetamine-associated seizures, AAS) were identified over 8 years." | 7.77 | Amphetamine-associated seizures: clinical features and prognosis. ( Brown, JW; Dunne, JW; Fatovic, DM; Fatovich, DM; Lawn, ND; Lee, J, 2011) |
| " Repeated exposure to MDMA (3×10mg/kg, ip) resulted in a reduction of 37-58% of GAD67-IR cells in the dentate gyrus (DG), CA1, and CA3 regions, as well as an increased susceptibility to kainic acid-induced seizures, both of which persisted for at least 30days following MDMA treatment." | 3.83 | MDMA decreases glutamic acid decarboxylase (GAD) 67-immunoreactive neurons in the hippocampus and increases seizure susceptibility: Role for glutamate. ( Gudelsky, GA; Herman, JP; Huff, CL; Morano, RL; Yamamoto, BK, 2016) |
| "Kainic acid (KA) causes seizures and neuronal loss in the hippocampus." | 3.80 | 3,4-Methylenedioxymethamphetamine enhances kainic acid convulsive susceptibility. ( Abad, S; Auladell, C; Camarasa, J; Camins, A; Escubedo, E; Junyent, F; Pallàs, M; Pubill, D, 2014) |
| "Forty-four patients presenting with first-ever seizure within 24 h of illicit use of amphetamine or related analogs (amphetamine-associated seizures, AAS) were identified over 8 years." | 3.77 | Amphetamine-associated seizures: clinical features and prognosis. ( Brown, JW; Dunne, JW; Fatovic, DM; Fatovich, DM; Lawn, ND; Lee, J, 2011) |
| "Patients almost invariably present with convulsions accompanied by sympathetic signs and symptoms such as hyperthermia." | 2.49 | Ecstasy intoxication as an unusual cause of epileptic seizures in young children. ( Desmet, K; Eerdekens, K; Lemmens, F; Pauwels, S; Penders, J; Poesen, K; Vermeersch, P, 2013) |
| "Chronic effects of MDMA abuse on seizure threshold have not been explored in detail so far." | 2.43 | MDMA and seizures: a dangerous liaison? ( Fornai, F; Giorgi, FS; Iudice, A; Lazzeri, G; Murri, L; Natale, G; Paparelli, A; Ruggieri, S, 2006) |
| " However, reports of adverse effects and fatalities have increased in the medical and popular press." | 2.41 | Agony and ecstasy: a review of MDMA effects and toxicity. ( Burgess, C; Gill, M; O'Donohoe, A, 2000) |
| "Convulsive seizures are among the most common problems involving the central nervous system." | 2.40 | [MDMA ("Ecstasy") use--an overview of psychiatric and medical sequelae]. ( Kraus, D; Schmolke, M; Thomasius, R, 1997) |
| " This case report indicates that even non-chronic MDMA use may cause subacute toxic encephalopathy in which the clinical evolution is paralleled by neuroimaging changes in specific cerebral areas." | 1.35 | Hippocampal remodelling after MDMA neurotoxicity: a single case study. ( Amistà, P; Battaglia, M; Bertagnoni, GE; Carollo, C; Costanzo, R; Lupi, A; Martinuzzi, A; Nifosì, F; Perini, G; Toffanin, T; Vestri, A, 2009) |
| "He presented with fever and seizures, tachycardia, hypertension, and hyperthermia." | 1.33 | Accidental ingestion of Ecstasy in a toddler. ( Chang, YJ; Chao, HC; Kong, MS; Lai, MW, 2005) |
| "Treatment to terminate the seizures necessitated intubation and ventilation, and cooling measures brought the temperature within normal limits." | 1.33 | Severe Ecstasy poisoning in a toddler. ( Duffy, MR; Swart, M, 2006) |
| "A patient presented to our unit with seizures and profound hyponatraemia after ingestion of a single tablet of ecstasy." | 1.30 | Hyponatraemia and seizures after ecstasy use. ( Alexander, WD; Banerjee, AK; Holmes, SB, 1999) |
| " The features of the stimulant-induced seizures were distinct and included the following: (1) the duration of convulsive activity was shortest for cocaine and longest for methamphetamine, (2) only MDMA produced a secondary clonic phase after the initial ictal event, and (3) 4-methylaminorex manifested a very steep dose-response curve." | 1.30 | Distinct features of seizures induced by cocaine and amphetamine analogs. ( Hanson, GR; Jensen, M; Johnson, M; White, HS, 1999) |
| "Flunarizine was also the only drug that antagonized methamphetamine-induced stereotypy." | 1.29 | Effects of L-type calcium channel antagonists on the serotonin-depleting actions of MDMA in rats. ( Calder, L; Clikeman, J; Finnegan, KT; Karler, R; Wei, S, 1993) |
| "Four patients presented with acute liver failure without hyperthermia." | 1.29 | Acute liver damage and ecstasy ingestion. ( Ellis, AJ; Portmann, B; Wendon, JA; Williams, R, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (21.43) | 18.2507 |
| 2000's | 21 (50.00) | 29.6817 |
| 2010's | 9 (21.43) | 24.3611 |
| 2020's | 3 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Huntjens, DW | 1 |
| Weersink, EPS | 1 |
| Hilarius, DL | 1 |
| Ran, NC | 1 |
| Franssen, EJF | 1 |
| Man, N | 1 |
| Sisson, SA | 1 |
| McKetin, R | 1 |
| Chrzanowska, A | 1 |
| Bruno, R | 1 |
| Dietze, PM | 1 |
| Price, O | 1 |
| Degenhardt, L | 1 |
| Gibbs, D | 1 |
| Salom, C | 1 |
| Peacock, A | 1 |
| Muskiewicz, DE | 1 |
| Resendiz-Gutierrez, F | 1 |
| Issa, O | 1 |
| Hall, FS | 1 |
| Armitage, MC | 1 |
| Bryant, RJ | 1 |
| Page, CB | 1 |
| Lappin, JM | 1 |
| Sara, GE | 1 |
| Pauwels, S | 1 |
| Lemmens, F | 1 |
| Eerdekens, K | 1 |
| Penders, J | 1 |
| Poesen, K | 1 |
| Desmet, K | 1 |
| Vermeersch, P | 1 |
| Kapoor, A | 1 |
| Jackson, KS | 1 |
| Abad, S | 1 |
| Junyent, F | 1 |
| Auladell, C | 1 |
| Pubill, D | 1 |
| Pallàs, M | 1 |
| Camarasa, J | 1 |
| Escubedo, E | 1 |
| Camins, A | 1 |
| Huff, CL | 1 |
| Morano, RL | 1 |
| Herman, JP | 1 |
| Yamamoto, BK | 1 |
| Gudelsky, GA | 1 |
| Nifosì, F | 1 |
| Martinuzzi, A | 1 |
| Toffanin, T | 1 |
| Costanzo, R | 1 |
| Vestri, A | 1 |
| Battaglia, M | 1 |
| Bertagnoni, GE | 1 |
| Lupi, A | 1 |
| Amistà, P | 1 |
| Carollo, C | 1 |
| Perini, G | 1 |
| Brown, JW | 1 |
| Dunne, JW | 1 |
| Fatovich, DM | 1 |
| Fatovic, DM | 1 |
| Lee, J | 1 |
| Lawn, ND | 1 |
| Westin, AA | 1 |
| Brede, WR | 1 |
| Papaseit, E | 1 |
| Vázquez, A | 1 |
| Pérez-Mañá, C | 1 |
| Pujadas, M | 1 |
| de la Torre, R | 1 |
| Farré, M | 1 |
| Nolla, J | 1 |
| Gowing, LR | 1 |
| Henry-Edwards, SM | 1 |
| Irvine, RJ | 1 |
| Ali, RL | 1 |
| Arnold, DH | 1 |
| Sue, YM | 1 |
| Lee, YL | 1 |
| Huang, JJ | 1 |
| Auer, J | 1 |
| Berent, R | 1 |
| Weber, T | 1 |
| Lassnig, E | 1 |
| Eber, B | 1 |
| Madhok, A | 1 |
| Boxer, R | 1 |
| Chowdhury, D | 1 |
| Lee, GY | 1 |
| Gong, GW | 1 |
| Vrodos, N | 1 |
| Brophy, BP | 1 |
| Ben-Abraham, R | 1 |
| Szold, O | 1 |
| Rudick, V | 1 |
| Weinbroum, AA | 1 |
| Melian, AM | 1 |
| Burillo-Putze, G | 1 |
| Campo, CG | 1 |
| Padron, AG | 1 |
| Ramos, CO | 1 |
| Campbell, S | 1 |
| Qureshi, T | 1 |
| McNamara, R | 1 |
| Kerans, A | 1 |
| O'Neill, B | 1 |
| Harkin, A | 1 |
| Giorgi, FS | 3 |
| Pizzanelli, C | 1 |
| Ferrucci, M | 2 |
| Lazzeri, G | 2 |
| Faetti, M | 1 |
| Giusiani, M | 1 |
| Pontarelli, F | 1 |
| Busceti, CL | 1 |
| Murri, L | 3 |
| Fornai, F | 3 |
| Chang, YJ | 1 |
| Lai, MW | 1 |
| Kong, MS | 1 |
| Chao, HC | 1 |
| Duffy, MR | 1 |
| Swart, M | 1 |
| Fang, CC | 1 |
| Lai, TI | 1 |
| Natale, G | 1 |
| Iudice, A | 1 |
| Ruggieri, S | 2 |
| Paparelli, A | 2 |
| Frenzilli, G | 1 |
| Blandini, F | 1 |
| Nigro, M | 1 |
| Kuwahara, T | 1 |
| Nakakura, T | 1 |
| Oda, S | 1 |
| Mori, M | 1 |
| Uehira, T | 1 |
| Okamoto, G | 1 |
| Yoshino, M | 1 |
| Sasakawa, A | 1 |
| Yajima, K | 1 |
| Umemoto, A | 1 |
| Takada, K | 1 |
| Makie, T | 1 |
| Yamamoto, Y | 1 |
| Finnegan, KT | 1 |
| Calder, L | 1 |
| Clikeman, J | 1 |
| Wei, S | 1 |
| Karler, R | 1 |
| Ellis, AJ | 1 |
| Wendon, JA | 1 |
| Portmann, B | 1 |
| Williams, R | 1 |
| Thomasius, R | 1 |
| Schmolke, M | 1 |
| Kraus, D | 1 |
| Cooper, AJ | 1 |
| Egleston, CV | 1 |
| Jansen, KL | 1 |
| Holmes, SB | 1 |
| Banerjee, AK | 1 |
| Alexander, WD | 1 |
| Hanson, GR | 1 |
| Jensen, M | 1 |
| Johnson, M | 1 |
| White, HS | 1 |
| Burgess, C | 1 |
| O'Donohoe, A | 1 |
| Gill, M | 1 |
| Shannon, M | 1 |
| Pannier, M | 1 |
| Radji, M | 1 |
| Ossart, M | 1 |
| Sawyer, J | 1 |
| Stephens, WP | 1 |
| Bedford Russell, AR | 1 |
| Schwartz, RH | 1 |
| Dawling, S | 1 |
6 reviews available for n-methyl-3,4-methylenedioxyamphetamine and Absence Seizure
| Article | Year |
|---|---|
Psychostimulant use and the brain.
Topics: Amphetamine; Amphetamine-Related Disorders; Brain; Central Nervous System Stimulants; Cocaine; Cocai | 2019 |
Ecstasy intoxication as an unusual cause of epileptic seizures in young children.
Topics: Female; Fever; Humans; Illicit Drugs; Infant; Male; N-Methyl-3,4-methylenedioxyamphetamine; Seizures | 2013 |
The health effects of ecstasy: a literature review.
Topics: Animals; Fever; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Seizures; Substance-R | 2002 |
MDMA and seizures: a dangerous liaison?
Topics: Acute Disease; Animals; Chronic Disease; Disease Susceptibility; Drug Interactions; Hallucinogens; K | 2006 |
[MDMA ("Ecstasy") use--an overview of psychiatric and medical sequelae].
Topics: Brain; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Neurologic Examination; Psychoses, Substance- | 1997 |
Agony and ecstasy: a review of MDMA effects and toxicity.
Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Chronic Disease; Fever; Hallucinogens; Humans; Hyponat | 2000 |
36 other studies available for n-methyl-3,4-methylenedioxyamphetamine and Absence Seizure
| Article | Year |
|---|---|
Severe epileptic seizures after accidental MDMA exposure in a 14-month-old child.
Topics: Child; Electroencephalography; Epilepsy; Humans; Infant; N-Methyl-3,4-methylenedioxyamphetamine; Sei | 2022 |
Trends in methamphetamine use, markets and harms in Australia, 2003-2019.
Topics: Amphetamine-Related Disorders; Australia; Bayes Theorem; Central Nervous System Stimulants; Humans; | 2022 |
Synthetic psychoactive cathinones: hypothermia and reduced lethality compared to methamphetamine and methylenedioxymethamphetamine.
Topics: Alkaloids; Animals; Behavior, Animal; Body Temperature Regulation; Central Nervous System Stimulants | 2020 |
Severe hyponatremia complicated by seizure following 3,4-methylenedioxymethamphetamine ingestion.
Topics: Adolescent; Brain Diseases; Eating; Female; Fluid Therapy; Glasgow Coma Scale; Humans; Hyponatremia; | 2018 |
Seizures presenting in pregnancy: eclampsia or something else?
Topics: Adrenergic Uptake Inhibitors; Diagnosis, Differential; Eclampsia; Female; Humans; N-Methyl-3,4-methy | 2013 |
3,4-Methylenedioxymethamphetamine enhances kainic acid convulsive susceptibility.
Topics: Animals; Astrocytes; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Convulsants; Dose-Respon | 2014 |
MDMA decreases glutamic acid decarboxylase (GAD) 67-immunoreactive neurons in the hippocampus and increases seizure susceptibility: Role for glutamate.
Topics: Animals; Body Temperature; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Agonis | 2016 |
Hippocampal remodelling after MDMA neurotoxicity: a single case study.
Topics: Adolescent; Anticonvulsants; Body Temperature Regulation; Cognition Disorders; Electroencephalograph | 2009 |
Amphetamine-associated seizures: clinical features and prognosis.
Topics: Adolescent; Adult; Amphetamine; Anticonvulsants; Central Nervous System Stimulants; Electroencephalo | 2011 |
[Paramethoxymethamphetamine].
Topics: Arrhythmias, Cardiac; Central Nervous System Stimulants; Hallucinogens; Humans; Illicit Drugs; Male; | 2011 |
Surviving life-threatening MDMA (3,4-methylenedioxymethamphetamine, ecstasy) toxicity caused by ritonavir (RTV).
Topics: Blood Component Transfusion; Contraindications; Drug Interactions; Fever; Fluid Therapy; Hallucinoge | 2012 |
Consultation with the specialist: the central serotonin syndrome: paradigm for psychotherapeutic misadventure.
Topics: Adolescent; Amphetamine-Related Disorders; Antidepressive Agents; Antitussive Agents; Anxiety Disord | 2002 |
Acute hyponatremia, seizure, and rhabdomyolysis after ecstasy use.
Topics: Adult; Female; Hallucinogens; Humans; Hyponatremia; Inappropriate ADH Syndrome; N-Methyl-3,4-methyle | 2002 |
Subarachnoid haemorrhage with "Ecstasy" abuse in a young adult.
Topics: Adolescent; Cerebral Angiography; Headache; Hemiplegia; Humans; Intracranial Aneurysm; Male; N-Methy | 2002 |
Atrial fibrillation in an adolescent--the agony of ecstasy.
Topics: Adolescent; Alcohol Drinking; Atrial Fibrillation; Diagnosis, Differential; Emergencies; Humans; Mal | 2003 |
'Ecstasy'-induced subarachnoid haemorrhage: an under-reported neurological complication?
Topics: Adult; Basilar Artery; Brain; Cerebral Angiography; Cerebral Arteries; Female; Hallucinogens; Headac | 2003 |
'Ecstasy' intoxication: life-threatening manifestations and resuscitative measures in the intensive care setting.
Topics: Adolescent; Adult; Coma; Critical Care; Female; Hallucinogens; Humans; Illicit Drugs; Israel; Male; | 2003 |
Accidental ecstasy poisoning in a toddler.
Topics: Accidents, Home; Benzodiazepines; Cardiac Complexes, Premature; Combined Modality Therapy; Fever; Hu | 2004 |
Taking Ecstasy... it's child's play!
Topics: Anticonvulsants; Critical Illness; Exanthema; Female; Hallucinogens; Hemodynamics; Humans; Hyponatre | 2005 |
Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA ("Ecstasy") and MDA ("Love").
Topics: 3,4-Methylenedioxyamphetamine; Animals; Area Under Curve; Behavior, Animal; Body Temperature; Brain | 2006 |
Previous exposure to (+/-) 3,4-methylenedioxymethamphetamine produces long-lasting alteration in limbic brain excitability measured by electroencephalogram spectrum analysis, brain metabolism and seizure susceptibility.
Topics: Animals; Biogenic Monoamines; Brain; Disease Susceptibility; Electroencephalography; Glucose; Kainic | 2005 |
Accidental ingestion of Ecstasy in a toddler.
Topics: Diagnosis, Differential; Fever; Humans; Hypertension; Infant; Male; N-Methyl-3,4-methylenedioxyamphe | 2005 |
Severe Ecstasy poisoning in a toddler.
Topics: Drug Overdose; Female; Hallucinogens; Humans; Infant; N-Methyl-3,4-methylenedioxyamphetamine; Seizur | 2006 |
Ecstasy poisoning in a toddler.
Topics: Child Abuse; Diagnosis, Differential; Drug Overdose; Hallucinogens; Humans; Infant; Male; N-Methyl-3 | 2006 |
DNA fragmentation and oxidative stress in the hippocampal formation: a bridge between 3,4-methylenedioxymethamphetamine (ecstasy) intake and long-lasting behavioral alterations.
Topics: Animals; Behavior, Animal; Cognition Disorders; Comet Assay; Disease Models, Animal; DNA Breaks, Dou | 2007 |
Problems in three Japanese drug users with Human Immunodeficiency Virus infection.
Topics: 5-Methoxytryptamine; Adult; Amyl Nitrite; Antiretroviral Therapy, Highly Active; Asian People; Drug | 2008 |
Effects of L-type calcium channel antagonists on the serotonin-depleting actions of MDMA in rats.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Calcium Channel Blockers; Cerebral Cortex; | 1993 |
Acute liver damage and ecstasy ingestion.
Topics: Adolescent; Adult; Fatal Outcome; Female; Fever; Humans; Hypotension; Liver; Liver Failure, Acute; L | 1996 |
Accidental ingestion of Ecstasy by a toddler: unusual cause for convulsion in a febrile child.
Topics: Akathisia, Drug-Induced; Child, Preschool; Deglutition; Diagnosis, Differential; Female; Fever; Hall | 1997 |
Ecstasy (MDMA) dependence.
Topics: Adult; Hallucinogens; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Seizures; Self Medicatio | 1999 |
Hyponatraemia and seizures after ecstasy use.
Topics: Adult; Furosemide; Hallucinogens; Humans; Hyponatremia; Male; N-Methyl-3,4-methylenedioxyamphetamine | 1999 |
Distinct features of seizures induced by cocaine and amphetamine analogs.
Topics: Animals; Central Nervous System Agents; Central Nervous System Stimulants; Diazepam; Dose-Response R | 1999 |
Methylenedioxymethamphetamine (MDMA, "Ecstasy").
Topics: Adult; Diagnosis, Differential; Disseminated Intravascular Coagulation; Emergency Treatment; Halluci | 2000 |
[Complications arising from occasional consumption of ecstasy].
Topics: Adult; Hallucinogens; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Seizures | 2001 |
Misuse of ecstasy.
Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Designer Drugs; Humans; Male; N-Methyl-3,4-methylenedioxy | 1992 |
Accidental ingestion of 'Ecstasy' (3,4-methylenedioxymethylamphetamine).
Topics: 3,4-Methylenedioxyamphetamine; Chlormethiazole; Heart Rate; Humans; Infant; Male; N-Methyl-3,4-methy | 1992 |