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n-hexane and Nervous System Diseases

n-hexane has been researched along with Nervous System Diseases in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199011 (57.89)18.7374
1990's7 (36.84)18.2507
2000's1 (5.26)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davies, DM; Grasso, P; Irvine, D; Sharratt, M1
Abou-Donia, MB1
Casey, HW; Cavender, FL; Graham, DG; Gralla, EJ; Salem, H; Swenberg, JA1
Altenkirch, H1
Anthony, DC; Boekelheide, K; Graham, DG; Maschmann, NA; Richards, RG; Shaw, BR; Wolfram, JW1
Altenkirch, H; Spencer, PS; Stoltenburg, G; Wagner, HM1
Couri, D; Milks, M1
DeCaprio, AP; Olajos, EJ; Weber, P1
Takeuchi, Y1
Costa, LG1
Csanády, GA; Dietz, W; Filser, JG; Kessler, W; Kreuzer, PE; Richter, M; Störmer, A1
Chu, NS; Huang, CC; Shih, TS; Wu, TN1
Albers, JW; Smith, AG1
Hattori, T; Kai, MR; Kuwabara, S; Nagase, H1
Kumamoto, T1
Al-Khatib, A; Bjertness, E; Kristensen, P; Nijem, K; Takrori, F1
Hisanaga, N; Huang, J; Kato, K; Ono, Y; Shibata, E; Sugimura, K; Takeuchi, Y1
Aminoff, MJ1
Abou-Donia, MB; Campbell, G; Lapadula, DM; Timmons, PR1

Reviews

7 review(s) available for n-hexane and Nervous System Diseases

ArticleYear
[Sniffing addiction and sniffing neuropathy. Social data, practices, clinical and neurological complications as well as experimental findings in solvents abuse].
    Schriftenreihe Neurologie, 1982, Volume: 23

    Topics: Adolescent; Adult; Animals; Axons; Butanones; Female; Hexanes; Humans; Hydrocarbons; Liver; Male; Microsomes, Liver; Nerve Tissue; Nervous System Diseases; Oxygenases; Paralysis; Pregnancy; Prognosis; Psychotherapy, Group; Rats; Socioeconomic Factors; Solvents; Substance-Related Disorders

1982
Toxicity and metabolism of the neurotoxic hexacarbons n-hexane, 2-hexanone, and 2,5-hexanedione.
    Annual review of pharmacology and toxicology, 1982, Volume: 22

    Topics: Animals; Biotransformation; Drug Synergism; Hexanes; Hexanones; Humans; Ketones; Lethal Dose 50; Methyl n-Butyl Ketone; Nervous System Diseases; Occupational Diseases; Rats; Solvents

1982
n-hexane polyneuropathy in Japan: a review of n-hexane poisoning and its preventive measures.
    Environmental research, 1993, Volume: 62, Issue:1

    Topics: Animals; Hexanes; Hexanones; Humans; Japan; Nervous System Diseases; Occupational Exposure; Poisoning

1993
Biomarker research in neurotoxicology: the role of mechanistic studies to bridge the gap between the laboratory and epidemiological investigations.
    Environmental health perspectives, 1996, Volume: 104 Suppl 1

    Topics: Acrylamide; Acrylamides; Animals; Biomarkers; Carbon Disulfide; Environmental Pollutants; Epidemiologic Methods; Hexanes; Humans; Insecticides; Nervous System Diseases; Organophosphorus Compounds; Research Design; Risk Assessment; Styrene; Styrenes

1996
Occupational neurotoxic diseases in Taiwan: a review of the outbreaks and clinical features.
    Changgeng yi xue za zhi, 1997, Volume: 20, Issue:2

    Topics: Carbon Disulfide; Disease Outbreaks; Hexanes; Humans; Hydrogen Sulfide; Lead Poisoning; Manganese Poisoning; Mercury Poisoning; Nervous System Diseases; Occupational Diseases; Polychlorinated Biphenyls; Taiwan

1997
[Organic solvents (poisoning)].
    Ryoikibetsu shokogun shirizu, 1999, Issue:27 Pt 2

    Topics: Gasoline; Hexanes; Humans; Methanol; Nervous System Diseases; Solvents; Toluene; Trichloroethylene

1999
Electrophysiologic recognition of certain occupation-related neurotoxic disorders.
    Neurologic clinics, 1985, Volume: 3, Issue:3

    Topics: Acrylamide; Acrylamides; Animals; Electrodiagnosis; Hexanes; Humans; Insecticides; Lead Poisoning; Mercury Poisoning; Nervous System Diseases; Occupational Diseases; Organophosphorus Compounds; Papio

1985

Trials

2 trial(s) available for n-hexane and Nervous System Diseases

ArticleYear
Comparative estimation of the neurotoxic risks of N-hexane and N-heptane in rats and humans based on the formation of the metabolites 2,5-hexanedione and 2,5-heptanedione.
    Advances in experimental medicine and biology, 1996, Volume: 387

    Topics: Administration, Inhalation; Adult; Animals; Body Burden; Cross-Linking Reagents; Half-Life; Heptanes; Hexanes; Hexanones; Humans; Ketones; Male; Nervous System Diseases; Pyrroles; Rats; Rats, Wistar; Risk Assessment

1996
n-Hexane neuropathy caused by addictive inhalation: clinical and electrophysiological features.
    European neurology, 1999, Volume: 41, Issue:3

    Topics: Administration, Inhalation; Adult; Electromyography; Hexanes; Humans; Japan; Male; Nervous System Diseases; Neural Conduction; Substance-Related Disorders

1999

Other Studies

10 other study(ies) available for n-hexane and Nervous System Diseases

ArticleYear
Neurophysiological and psychological disorders and occupational exposure to organic solvents.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1984, Volume: 22, Issue:10

    Topics: Aging; Alcoholic Intoxication; Animals; Behavior, Animal; Carbon Disulfide; Chloroform; Electroencephalography; Ethylene Dichlorides; Hexanes; Humans; Hydrocarbons; Lead Poisoning; Mental Disorders; Mercury Poisoning; Methyl Chloride; Methylene Chloride; Nervous System Diseases; Occupational Diseases; Paint; Personality; Solvents; Styrene; Styrenes; Toluene; Tomography, X-Ray Computed; Trichloroethylene; Wechsler Scales; Xylenes

1984
Interaction between neurotoxicities induced by organophosphorus and long-chain hexacarbon compounds.
    Neurotoxicology, 1983,Winter, Volume: 4, Issue:4

    Topics: Animals; Chickens; Drug Synergism; Female; Glycols; Hexanes; Hexanones; Insecticides; Ketones; Methyl n-Butyl Ketone; Nervous System Diseases; Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester

1983
A 13-week vapor inhalation study of n-hexane in rats with emphasis on neurotoxic effects.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:2 Pt 1

    Topics: Air; Animals; Body Weight; Female; Gases; Hexanes; Hydrogen-Ion Concentration; Male; Nervous System Diseases; Organ Size; Rats; Rats, Inbred F344

1984
Studies of the molecular pathogenesis of hexane neuropathy. II. Evidence that pyrrole derivatization of lysyl residues leads to protein crosslinking.
    Toxicology and applied pharmacology, 1982, Volume: 64, Issue:3

    Topics: Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Hexanes; Hexanones; Lysine; Nervous System Diseases; Pyrroles

1982
Nervous system responses of rats to subchronic inhalation of N-hexane and N-hexane + methyl-ethyl-ketone mixtures.
    Journal of the neurological sciences, 1982, Volume: 57, Issue:2-3

    Topics: Animals; Axons; Butanones; Cytoskeleton; Environmental Exposure; Hexanes; Male; Medulla Oblongata; Myelin Sheath; Nervous System Diseases; Paralysis; Peripheral Nerves; Rats; Rats, Inbred Strains; Spinal Cord

1982
Covalent binding of a neurotoxic n-hexane metabolite: conversion of primary amines to substituted pyrrole adducts by 2,5-hexanedione.
    Toxicology and applied pharmacology, 1982, Sep-30, Volume: 65, Issue:3

    Topics: Amines; Amino Acids; Animals; Chemical Phenomena; Chemistry; Chickens; Chromogenic Compounds; Female; Hexanes; Hexanones; Ketones; Nervous System Diseases; Proteins; Pyrroles

1982
n-Hexane neuropathy due to rubber cement sniffing.
    Muscle & nerve, 1997, Volume: 20, Issue:11

    Topics: Action Potentials; Adult; Axons; Electrophysiology; Hexanes; Humans; Male; Muscles; Nervous System Diseases; Substance-Related Disorders

1997
Prevalence of neuropsychiatric and mucous membrane irritation complaints among Palestinian shoe factory workers exposed to organic solvents and plastic compounds.
    American journal of industrial medicine, 2001, Volume: 40, Issue:2

    Topics: Adolescent; Adult; Health Surveys; Hexanes; Humans; Male; Methylene Chloride; Mucous Membrane; Nervous System Diseases; Occupational Exposure; Occupations; Polyvinyl Chloride; Shoes; Solvents; Surveys and Questionnaires; Toluene

2001
Effects of chronic n-hexane exposure on nervous system-specific and muscle-specific proteins.
    Archives of toxicology, 1989, Volume: 63, Issue:5

    Topics: Animals; Body Weight; Electrophysiology; Hexanes; Male; Muscle Proteins; Muscles; Nerve Tissue Proteins; Nervous System Diseases; Neural Conduction; Peripheral Nerves; Phosphopyruvate Hydratase; Rats; Rats, Inbred Strains

1989
The synergism of n-hexane-induced neurotoxicity by methyl isobutyl ketone following subchronic (90 days) inhalation in hens: induction of hepatic microsomal cytochrome P-450.
    Toxicology and applied pharmacology, 1985, Volume: 81, Issue:1

    Topics: Aniline Hydroxylase; Animals; Ataxia; Atmosphere Exposure Chambers; Body Weight; Chickens; Cytochrome P-450 Enzyme System; Drug Synergism; Enzyme Induction; Female; Hexanes; Ketones; Methyl n-Butyl Ketone; Microsomes, Liver; Nervous System Diseases; Paralysis; Peripheral Nerves; Spinal Cord; Time Factors

1985