Compounds > n-formylmethionine leucyl-phenylalanine

n-formylmethionine leucyl-phenylalanine and Blood Poisoning

n-formylmethionine leucyl-phenylalanine has been researched along with Blood Poisoning in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.67)18.7374
1990's7 (23.33)18.2507
2000's12 (40.00)29.6817
2010's7 (23.33)24.3611
2020's2 (6.67)2.80

Authors

AuthorsStudies
Hashiguchi, N; Junger, WG; Ledderose, C; Rusu, C; Valsami, EA1
Deng, XM; Li, HR; Li, P; Liu, Q; Wang, JF; Wang, Y; Yu, CM; Zhu, CL1
Komic, A; Martinez-Quinones, P; McCarthy, CG; Webb, RC; Wenceslau, CF1
Baban, B; McCarthy, CG; NeSmith, E; Szasz, T; Webb, RC; Wenceslau, CF1
Deosarkar, S; Kiani, MF; Kilpatrick, LE; King, DJ; Prabhakarpandian, B; Soroush, F; Tang, Y; Zhang, T1
Cybulsky, M; Dimitriou, ID; Fine, N; Glogauer, M; Haitsma, J; Ibrahim, H; Kubes, P; La Rose, J; Petri, B; Rottapel, R; Rullo, J; Sandí, MJ1
Cao, Z; Chen, K; Gong, W; Jin, L; Lai, X; Liao, Y; Liu, M; Shi, Y; Wang, C; Wang, JM; Ye, L; Zhou, N1
Keshamouni, VG; Milam, JE; Narala, VR; Newstead, MW; Reddy, RC; Standiford, TJ1
Chen, Y; Hirsh, MI; Inoue, Y; Junger, WG; Pauzenberger, R1
Calfee, CS; Matthay, MA1
Brohi, K; Chen, Y; Hauser, CJ; Itagaki, K; Junger, W; Raoof, M; Sumi, Y; Sursal, T; Zhang, Q1
Krumholz, W; Stubbe, K; Szalay, G1
Arpin, M; Bienvenu, J; Debard, AL; Lepape, A; Maghni, K; Monneret, G; Pachot, A; Venet, F1
Blecher, S; Dalboni, MA; Kallas, EG; Martins, PS; Neto, MC; Salomão, R1
Chang, SL; House, SD; Jiang, Y; Ocasio, FM1
Alves-Filho, JC; Arraes, SM; Auxiliadora Martins, M; Barja-Fidalgo, C; Basile-Filho, A; Cunha, FQ; da Silva, SV; de Paula Neto, HA; Freitas, MS; Tavares-Murta, BM1
Chouker, A; Hoelzl, A; Hummel, T; Kaufmann, I; Peter, K; Schliephake, F; Thiel, M1
de Boer, M; Koenderman, L; Kuijpers, TW; Mascart-Lemone, F; Roos, D; van Zwieten, R; Verhoeven, AJ1
Hammerle, AF; Mayer, N; Micksche, M; Oismüller, C; Steltzer, H1
Chen, WY; Lei, HY; Lu, CC; Wang, JY1
Plusa, SM; Primrose, JN; Webster, N1
Murphy, PG; Ogilvy, AJ; Whiteley, SM1
Arfors, KE; Chambers, JD; Messmer, K; Peter, K; Thiel, M; von Andrian, UH; Zourelidis, C1
Curnutte, JT; Ding, J; Erickson, R; Guo, RF; Huber-Lang, M; Kunkel, RG; Lu, KT; McGuire, SR; Padgaonkar, VA; Sarma, VJ; Ward, PA; Younkin, EM1
Fujisawa, J; Inada, T; Kobayashi, Y; Nakao, S; Shingu, K; Taniuchi, S1
Fujimi, S; Hosotsubo, H; Koh, T; Kuwagata, Y; Nakamori, Y; Ogura, H; Shimazu, T; Sugimoto, H; Tanaka, H1
Cunha, FQ; Ferreira, RB; Ferreira, SH; Murta, EF; Oliveira, CH; Silva-Vergara, ML; Tavares-Murta, BM; Zaparoli, M1
Danner, RL; Doerfler, ME; Parrillo, JE; Stuetz, P; Van Dervort, AL1
Farrin-Rusk, C; Millard, JR; Zimmerman, JJ1
Kwan, DK; Smith, CW; Stickle, JE1

Reviews

1 review(s) available for n-formylmethionine leucyl-phenylalanine and Blood Poisoning

ArticleYear
The role of G protein-coupled receptor in neutrophil dysfunction during sepsis-induced acute respiratory distress syndrome.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Animals; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, G-Protein-Coupled; Respiratory Distress Syndrome; Sepsis

2023

Trials

1 trial(s) available for n-formylmethionine leucyl-phenylalanine and Blood Poisoning

ArticleYear
In vivo modulation of human neutrophil function by pentoxifylline in patients with septic syndrome.
    Shock (Augusta, Ga.), 1995, Volume: 4, Issue:3

    Topics: Adult; Humans; Infusions, Intravenous; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Phosphodiesterase Inhibitors; Respiratory Burst; Sepsis; Tetradecanoylphorbol Acetate

1995

Other Studies

28 other study(ies) available for n-formylmethionine leucyl-phenylalanine and Blood Poisoning

ArticleYear
Optimized flow cytometry assays to monitor neutrophil activation in human and mouse whole blood samples.
    Journal of immunological methods, 2023, Volume: 512

    Topics: Animals; Flow Cytometry; Humans; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Reactive Oxygen Species; Receptors, Formyl Peptide; Sepsis

2023
Targeting Endothelial Barrier Dysfunction Caused by Circulating Bacterial and Mitochondrial N-Formyl Peptides With Deformylase.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Bacteremia; Disease Susceptibility; Drug Development; Endothelium, Vascular; Humans; Mitochondria; Molecular Targeted Therapy; N-Formylmethionine Leucyl-Phenylalanine; Permeability; Receptors, Formyl Peptide; Sepsis; Systemic Inflammatory Response Syndrome

2019
Mitochondrial N-formyl peptides cause airway contraction and lung neutrophil infiltration via formyl peptide receptor activation.
    Pulmonary pharmacology & therapeutics, 2016, Volume: 37

    Topics: Adolescent; Adult; Animals; Humans; Lung Injury; Male; Mast Cells; Mitochondria; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Infiltration; Neutrophils; Rats; Rats, Wistar; Receptors, Formyl Peptide; Respiratory Insufficiency; Sepsis; Systemic Inflammatory Response Syndrome; Young Adult

2016
A novel microfluidic assay reveals a key role for protein kinase C δ in regulating human neutrophil-endothelium interaction.
    Journal of leukocyte biology, 2016, Volume: 100, Issue:5

    Topics: Animals; Cell Adhesion; Chemotaxis, Leukocyte; Disease Models, Animal; E-Selectin; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Lung; Male; Microfluidic Analytical Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Protein Kinase C-delta; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Rheology; Sepsis; Tumor Necrosis Factor-alpha

2016
GEF-H1 is necessary for neutrophil shear stress-induced migration during inflammation.
    The Journal of cell biology, 2016, Oct-10, Volume: 215, Issue:1

    Topics: Animals; Cell Adhesion; Cell Movement; HL-60 Cells; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Mice; Microtubules; Models, Biological; Muscles; Myosin Light Chains; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Infiltration; Neutrophils; Phosphorylation; Polymerization; Rho Guanine Nucleotide Exchange Factors; Sepsis; Stress, Mechanical

2016
Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization.
    Scientific reports, 2017, 02-10, Volume: 7

    Topics: Actins; Animals; Cell Movement; Chemokine CCL2; Chemotactic Factors; Chemotaxis; Endocytosis; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; HEK293 Cells; Humans; Inflammation Mediators; Interleukin-6; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mice; N-Formylmethionine Leucyl-Phenylalanine; Niacin; Protein Kinase C; Protein Kinase Inhibitors; RAW 264.7 Cells; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Sepsis; Up-Regulation

2017
Sepsis-induced inhibition of neutrophil chemotaxis is mediated by activation of peroxisome proliferator-activated receptor-{gamma}.
    Blood, 2008, Nov-15, Volume: 112, Issue:10

    Topics: Actins; Anilides; Animals; Antineoplastic Agents; Cell Adhesion; Chemotaxis; Chromans; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fibrinogen; HL-60 Cells; Humans; Inflammation; Interleukin-4; Interleukin-8; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; N-Formylmethionine Leucyl-Phenylalanine; PPAR gamma; Prostaglandin D2; Sepsis; Thiazolidinediones; Troglitazone; Tumor Necrosis Factor-alpha; Up-Regulation

2008
Hypertonic saline up-regulates A3 adenosine receptor expression of activated neutrophils and increases acute lung injury after sepsis.
    Critical care medicine, 2008, Volume: 36, Issue:9

    Topics: Animals; Cell Degranulation; Humans; Lung; Mice; Mice, Knockout; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Peritoneal Cavity; Peroxidase; Random Allocation; Receptor, Adenosine A3; Respiratory Distress Syndrome; Saline Solution, Hypertonic; Sepsis; Time Factors

2008
Clinical immunology: Culprits with evolutionary ties.
    Nature, 2010, Mar-04, Volume: 464, Issue:7285

    Topics: Acute Lung Injury; Animals; DNA, Mitochondrial; Humans; Immunity, Innate; Mitochondria; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sepsis; Systemic Inflammatory Response Syndrome; Wounds and Injuries

2010
Circulating mitochondrial DAMPs cause inflammatory responses to injury.
    Nature, 2010, Mar-04, Volume: 464, Issue:7285

    Topics: Acute Lung Injury; Animals; Calcium Signaling; Cells, Cultured; CpG Islands; DNA, Mitochondrial; Femur; Fractures, Bone; Humans; Immunity, Innate; Liver; Male; Mitochondria; Mitogen-Activated Protein Kinases; Muscle, Skeletal; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Formyl Peptide; Sepsis; Systemic Inflammatory Response Syndrome; Toll-Like Receptor 9; Wounds and Injuries

2010
[The influence of various adjuvant drugs used in intensive care on monocyte chemotaxis].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2002, Volume: 37, Issue:8

    Topics: Adjuvants, Anesthesia; Chemotaxis, Leukocyte; Drug Interactions; Humans; In Vitro Techniques; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Sepsis

2002
Calcitonin gene related peptide and N-procalcitonin modulate CD11b upregulation in lipopolysaccharide activated monocytes and neutrophils.
    Intensive care medicine, 2003, Volume: 29, Issue:6

    Topics: Biomarkers; Calcitonin; Calcitonin Gene-Related Peptide; CD11b Antigen; Cells, Cultured; Chemotaxis, Leukocyte; Colforsin; Cyclic AMP; Drug Evaluation, Preclinical; Flow Cytometry; Humans; Inflammation; Lipopolysaccharides; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Precursors; Rolipram; Sepsis; Tumor Necrosis Factor-alpha; Up-Regulation

2003
Upregulation of reactive oxygen species generation and phagocytosis, and increased apoptosis in human neutrophils during severe sepsis and septic shock.
    Shock (Augusta, Ga.), 2003, Volume: 20, Issue:3

    Topics: Annexin A5; Apoptosis; Coloring Agents; Enzyme Inhibitors; Fluoresceins; Humans; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Propidium; Reactive Oxygen Species; Respiratory Burst; Sepsis; Shock; Staphylococcus aureus; Up-Regulation

2003
Chronic morphine accelerates the progression of lipopolysaccharide-induced sepsis to septic shock.
    Journal of neuroimmunology, 2004, Volume: 149, Issue:1-2

    Topics: Animals; Antithrombin III; Blood Pressure; Body Temperature; Cell Communication; Corticosterone; Disease Progression; Drug Interactions; Endothelial Cells; Endotoxins; Enzyme-Linked Immunosorbent Assay; Interleukin-1; Interleukin-6; Leukocytes; Lipopolysaccharides; Male; Morphine; N-Formylmethionine Leucyl-Phenylalanine; Narcotics; Peptide Hydrolases; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sepsis; Shock, Septic; Time Factors; Tumor Necrosis Factor-alpha

2004
Impaired neutrophil chemotaxis in sepsis associates with GRK expression and inhibition of actin assembly and tyrosine phosphorylation.
    Blood, 2006, Nov-01, Volume: 108, Issue:9

    Topics: Actins; beta-Adrenergic Receptor Kinases; Cell Movement; Chemotaxis, Leukocyte; Cytokines; DNA Primers; G-Protein-Coupled Receptor Kinase 2; G-Protein-Coupled Receptor Kinase 5; Humans; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphotyrosine; Protein Serine-Threonine Kinases; Receptors, Interleukin-8A; Reverse Transcriptase Polymerase Chain Reaction; Sepsis

2006
Polymorphonuclear leukocyte dysfunction syndrome in patients with increasing sepsis severity.
    Shock (Augusta, Ga.), 2006, Volume: 26, Issue:3

    Topics: C-Reactive Protein; Calcimycin; Calcitonin; CD18 Antigens; Humans; Hydrogen Peroxide; Interleukin-6; Leukocyte Count; Middle Aged; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Opsonin Proteins; Phagocytosis; Protein Precursors; Sepsis; Severity of Illness Index; Shock, Septic; Syndrome; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan

2006
A novel syndrome of severe neutrophil dysfunction: unresponsiveness confined to chemotaxin-induced functions.
    Blood, 1993, May-15, Volume: 81, Issue:10

    Topics: Actins; Antigens, CD; Calcimycin; Calcium; CD18 Antigens; CD4 Antigens; CD8 Antigens; Cell Adhesion; Cell Aggregation; Chemotaxis, Leukocyte; Cytochalasin B; Endothelium, Vascular; Female; Humans; Immunologic Deficiency Syndromes; In Vitro Techniques; Infant, Newborn; Kinetics; Leukocyte Count; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Reference Values; Sepsis; Syndrome; T-Lymphocyte Subsets

1993
Direct measurement of neutrophil F-actin content in microvolume whole blood samples.
    International archives of allergy and immunology, 1996, Volume: 110, Issue:4

    Topics: Actins; Adult; Blood Chemical Analysis; Cell Separation; Coloring Agents; Diseases in Twins; Flow Cytometry; Humans; Infant, Newborn; Kinetics; Lymphocytes; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides, Cyclic; Sepsis

1996
Neutrophil adhesion molecule expression and response to stimulation with bacterial wall products in humans is unaffected by parenteral nutrition.
    Clinical science (London, England : 1979), 1996, Volume: 91, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Cell Adhesion Molecules; Female; Flow Cytometry; Humans; Integrin alphaXbeta2; L-Selectin; Lewis X Antigen; Lipids; Lipopolysaccharides; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Parenteral Nutrition, Total; Sepsis; Stimulation, Chemical

1996
The effect of propofol on the neutrophil respiratory burst.
    European journal of anaesthesiology, 1996, Volume: 13, Issue:5

    Topics: Adult; Anesthetics, Intravenous; Fat Emulsions, Intravenous; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Propofol; Respiratory Burst; Sepsis

1996
Expression of beta 2-integrins and L-selectin on polymorphonuclear leukocytes in septic patients.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1997, Volume: 29, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Calcimycin; CD18 Antigens; Female; Humans; L-Selectin; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sepsis; Severity of Illness Index; Survivors; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1997
Role of C5a in multiorgan failure during sepsis.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jan-15, Volume: 166, Issue:2

    Topics: Acidosis; Alkalosis, Respiratory; Amino Acid Sequence; Animals; Cecum; Chemotaxis, Leukocyte; Complement C5a; Electrophoresis, Polyacrylamide Gel; Immune Sera; Iodine Radioisotopes; Kidney; Ligation; Male; Molecular Sequence Data; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Binding; Rats; Rats, Long-Evans; Recombinant Proteins; Sepsis; Tritium

2001
Propofol depressed neutrophil hydrogen peroxide production more than midazolam, whereas adhesion molecule expression was minimally affected by both anesthetics in rats with abdominal sepsis.
    Anesthesia and analgesia, 2001, Volume: 92, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Hydrogen Peroxide; Integrin alphaXbeta2; Macrophage-1 Antigen; Male; Midazolam; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Propofol; Rats; Rats, Sprague-Dawley; Sepsis

2001
Activated polymorphonuclear leukocytes enhance production of leukocyte microparticles with increased adhesion molecules in patients with sepsis.
    The Journal of trauma, 2002, Volume: 52, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; E-Selectin; Female; Flow Cytometry; Humans; Immunohistochemistry; Leukocyte Elastase; Macrophage-1 Antigen; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sepsis; Superoxides; Thrombomodulin

2002
Failure of neutrophil chemotactic function in septic patients.
    Critical care medicine, 2002, Volume: 30, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemotaxis, Leukocyte; Female; Humans; Leukotriene B4; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Prognosis; Prospective Studies; Sepsis

2002
Antiendotoxin activity of lipid A analogues: requirements of the chemical structure.
    Pharmaceutical research, 1990, Volume: 7, Issue:3

    Topics: Bacterial Infections; Chemical Phenomena; Chemistry; Endotoxins; Glycolipids; Humans; In Vitro Techniques; Lipid A; Myristic Acids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sepsis; Superoxides; Trypan Blue

1990
Septic plasma suppresses superoxide anion synthesis by normal homologous polymorphonuclear leukocytes.
    Critical care medicine, 1989, Volume: 17, Issue:12

    Topics: Adult; Aged; Anions; Child; Child, Preschool; Cytochrome c Group; Female; Humans; Infant; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophils; Sepsis; Shock, Septic; Spectrophotometry; Superoxides

1989
Neutrophil function in the dog: shape change and response to a synthetic tripeptide.
    American journal of veterinary research, 1985, Volume: 46, Issue:1

    Topics: Animals; Chemotaxis, Leukocyte; Dog Diseases; Dogs; Female; Humans; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Sepsis; Species Specificity

1985