n-formylmethionine leucyl-phenylalanine has been researched along with Autosomal Recessive Chronic Granulomatous Disease in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (47.73) | 18.7374 |
| 1990's | 17 (38.64) | 18.2507 |
| 2000's | 6 (13.64) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arias, AA; Dinauer, MC; Kellner, JD; Lewis, DB; Li, XJ; Marchal, CC; Matute, JD; Meroueh, SO; Nauseef, WM; Steele, M; Stull, ND; Waterhouse, CC; Wright, NA; Wrobel, I; Yu, W | 1 |
| Német, K; Selmeczy, Z; Szelényi, J; Vizi, ES | 1 |
| Bordigoni, P; Bost-Bru, C; Brion, JP; Durant-Vital, D; Floret, D; Gatel, P; Guillot, M; Li, XJ; Maquet, E; Martel, C; Michel, G; Morel, F; Stasia, MJ; Voelckel, MA | 1 |
| Alvord, WG; Gallin, JI; Kuhns, DB; Lekstrom-Himes, JA | 1 |
| Alfinito, F; Barone, L; Becchimanzi, C; Cacciapuoti, C; Rotoli, B; Ruggiero, G; Sica, M; Terrazzano, G | 1 |
| McPhail, LC; Snyderman, R | 1 |
| Fletcher, MP; Gallin, JI; Seligmann, BE | 1 |
| Clark, RA; Szot, S | 1 |
| Johnston, RB; McPhail, LC; Musson, RA; Shafran, H | 1 |
| English, D; Lukens, JN | 1 |
| Valerius, NH | 1 |
| Feinmark, SJ; Malmsten, C; Palmblad, J; Udén, AM | 1 |
| Gallin, JI; Nath, J | 2 |
| Mandell, GL; Salata, RA; Sullivan, JA | 1 |
| Lew, PD; Pozzan, T; Seger, RA; Wollheim, C | 1 |
| Andrews, PC; Babior, BM | 1 |
| Chused, TM; Gallin, JI; Seligmann, B | 1 |
| Káposzta, R; Maródi, L | 1 |
| Dusi, S; Rossi, F | 1 |
| Bernardo, J; Brennan, L; Brink, HF; Newburger, PE; Ortiz, MF; Simons, ER | 1 |
| Belohradsky, BH; Buth, S; Gahr, M; Jendrossek, V; Liese, J; Peters, AM; Wintergerst, U | 1 |
| Donini, M; Dusi, S; Rossi, F | 1 |
| Dunn, GA; Segal, AW; Zicha, D | 1 |
| Gahr, M; Heyden, S; Jendrossek, V; Neubauer, B; Ritzel, A | 1 |
| Ahlin, A; Elinder, G; Palmblad, J | 1 |
| Farkas, L; Geiszt, M; Kapus, A; Ligeti, E; Német, K | 1 |
| Bordigoni, P; Demaurex, N; Lardy, B; Martel, C; Maturana, A; Morel, F; Rousseau, P; Stasia, MJ | 1 |
| Bass, DA; Bauldry, SA; Nasrallah, VN | 1 |
| Bonney, RJ; Davies, P; Dijkman, JH; Green, BG; Hanlon, WA; Humes, JJ; Knight, WB; Kramps, JA; Mumford, R; Stolk, J | 1 |
| Német, K; Petrányi, G; Szabó, A | 1 |
| Anderson, DC; Brown, EJ; Graham, IL; Gresham, HD | 1 |
| Palmblad, J; Ringertz, B | 1 |
| Ank, BJ; Roberts, RL; Stiehm, ER | 2 |
| Lazzari, KG; Proto, P; Simons, ER | 1 |
| Hasui, M; Hirabayashi, Y; Kobayashi, Y; Komiyama, Y; Masuda, M; Murakami, T; Murata, K | 1 |
| Kramer, IM; Roos, D; van der Bend, RL; Verhoeven, AJ | 1 |
| Bender, JG; Chenoweth, DE; Steinkamp, JA; Van Epps, DE | 1 |
| Falloon, J; Gallin, JI | 1 |
| Anderson, R; Ras, GJ; Theron, AJ | 1 |
| Roos, D; van Schaik, ML; Verhoeven, AJ; Weening, RS | 1 |
| Kramer, IM; Roos, D; van der Bend, RL; Verhoeven, AJ; Weening, RS | 1 |
| Babior, BM; Curnutte, JT; Okamura, N; Roberts, RL | 1 |
2 review(s) available for n-formylmethionine leucyl-phenylalanine and Autosomal Recessive Chronic Granulomatous Disease
| Article | Year |
|---|---|
Modulation of tubulin tyrosinolation in human polymorphonuclear leukocytes (PMM).
Topics: Anaerobiosis; Antioxidants; Ascorbic Acid; Carboxypeptidases; Chediak-Higashi Syndrome; Cyclohexanones; Diamide; Granulomatous Disease, Chronic; Humans; Methylene Blue; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Peptide Synthases; Protein Processing, Post-Translational; Tubulin; Tyrosine | 1984 |
When should granulocyte function be checked?
Topics: Cell Adhesion; Cell Migration Inhibition; Chediak-Higashi Syndrome; Chemotaxis, Leukocyte; Cytochrome c Group; Cytoplasmic Granules; Cytotoxicity Tests, Immunologic; Granulomatous Disease, Chronic; Humans; Immunologic Deficiency Syndromes; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Nitroblue Tetrazolium; Oxidation-Reduction; Phagocytosis | 1992 |
1 trial(s) available for n-formylmethionine leucyl-phenylalanine and Autosomal Recessive Chronic Granulomatous Disease
| Article | Year |
|---|---|
Dose-dependent enhancements by interferon-gamma on functional responses of neutrophils from chronic granulomatous disease patients.
Topics: Adolescent; Adult; Aspergillus; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Interferon-gamma; Kinetics; Luminescent Measurements; Male; Membrane Glycoproteins; N-Formylmethionine Leucyl-Phenylalanine; NADH Dehydrogenase; NADPH Dehydrogenase; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Phagocytosis; Phosphoproteins; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
41 other study(ies) available for n-formylmethionine leucyl-phenylalanine and Autosomal Recessive Chronic Granulomatous Disease
| Article | Year |
|---|---|
A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity.
Topics: Adult; Amino Acid Substitution; Carcinogens; Cell Line, Tumor; Child; Codon, Terminator; DNA Mutational Analysis; Female; Genes, Recessive; Genetic Diseases, Inborn; Granulomatous Disease, Chronic; Heterozygote; Humans; Male; Mutation, Missense; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phagocytosis; Phorbol Esters; Phosphatidylinositol Phosphates; Superoxides | 2009 |
The inducibility of TNF-alpha production is different in the granulocytic and monocytic differentiated forms of wild type and CGD-mutant PLB-985 cells.
Topics: Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Granulocytes; Granulomatous Disease, Chronic; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages; Monocytes; Mutation; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Cell Surface; Receptors, Complement 3b; Receptors, IgG; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 2003 |
Characterization of six novel mutations in the CYBB gene leading to different sub-types of X-linked chronic granulomatous disease.
Topics: Genotype; Granulomatous Disease, Chronic; Humans; Immunoblotting; Male; Membrane Glycoproteins; Mutation; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidase 2; NADPH Oxidases; Phenotype; Tetradecanoylphorbol Acetate | 2005 |
Inhibition of human neutrophil IL-8 production by hydrogen peroxide and dysregulation in chronic granulomatous disease.
Topics: Blotting, Northern; Cytokines; Enzyme Activation; Enzyme Inhibitors; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Reactive Oxygen Species; RNA, Messenger | 2005 |
Glycosyl-phosphatidyl-inositol-defective granulocytes from paroxysmal nocturnal haemoglobinuria patients show increased bacterial ingestion but reduced respiratory burst induction.
Topics: Adult; Animals; Carcinogens; Cells, Cultured; Enzyme Activation; Escherichia coli; Glycosylphosphatidylinositols; Granulocytes; Granulomatous Disease, Chronic; Hematopoiesis; Hemoglobinuria, Paroxysmal; Humans; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phagocytosis; Protein Kinase C; Respiratory Burst; Tetradecanoylphorbol Acetate | 2007 |
Mechanisms of regulating the respiratory burst in leukocytes.
Topics: Animals; Arachidonic Acids; Calcimycin; Calcium; Cytoplasmic Granules; Electric Conductivity; Granulomatous Disease, Chronic; Humans; Leukocytes; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nucleotides, Cyclic; Oxygen Consumption; Peroxidase; Protein Kinases; Tetradecanoylphorbol Acetate | 1984 |
Correlation of human neutrophil secretion, chemoattractant receptor mobilization, and enhanced functional capacity.
Topics: 1-Butanol; Butanols; Calcimycin; Calcium; Chemotaxis, Leukocyte; Cycloheximide; Cytoplasmic Granules; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Lactoferrin; Methionine; Muramidase; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Pinocytosis; Puromycin; Receptors, Immunologic; Superoxides; Tetradecanoylphorbol Acetate | 1982 |
Chemotactic factor inactivation by stimulated human neutrophils mediated by myeloperoxidase-catalyzed methionine oxidation.
Topics: Aminopeptidases; Candidiasis; Catalysis; Chemotactic Factors; Complement C5; Complement C5a; Granulomatous Disease, Chronic; Humans; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peroxidase; Peroxidases; Sulfides; Tetradecanoylphorbol Acetate; Zymosan | 1982 |
Differences in the ability of human peripheral blood monocytes and in vitro monocyte-derived macrophages to produce superoxide anion: studies with cells from normals and patients with chronic granulomatous disease.
Topics: Adult; Calcimycin; Cells, Cultured; Female; Granulomatous Disease, Chronic; Humans; Infant; Macrophages; Male; Monocytes; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Opsonin Proteins; Oxygen; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1982 |
Regulation of neutrophil inflammatory mediator release: chemotactic peptide activation of stimulus-dependent cytotoxicity.
Topics: Chemotactic Factors; Chromium Radioisotopes; Cytotoxicity, Immunologic; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Inflammation; Interleukin-8; Male; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peroxidase; Tetradecanoylphorbol Acetate | 1983 |
Chemotaxis, spreanding nd oxidative metabolism of neutrophils: influence of albumin in vitro.
Topics: Caseins; Cell Adhesion; Cell Movement; Chemotaxis, Leukocyte; Escherichia coli; Granulomatous Disease, Chronic; Humans; Male; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Oxygen Consumption; Serum Albumin; Superoxides | 1983 |
Leukotriene biosynthesis by polymorphonuclear leukocytes from two patients with chronic granulomatous disease.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Calcimycin; Granulomatous Disease, Chronic; Humans; Leukotriene B4; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils | 1983 |
Studies in normal and chronic granulomatous disease neutrophils indicate a correlation of tubulin tyrosinolation with the cellular redox state.
Topics: Anaerobiosis; Antioxidants; Calcimycin; Diamide; Granulomatous Disease, Chronic; Humans; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Oxidation-Reduction; Sulfhydryl Reagents; Tubulin; Tyrosine | 1983 |
Visualization of hydrogen peroxide in living polymorphonuclear neutrophils utilizing leucodiacetyl 2',7'-dichlorofluorescin: photomicrographic and microphotometric studies.
Topics: Catalase; Dose-Response Relationship, Drug; Fluoresceins; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Microscopy, Fluorescence; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Superoxide Dismutase | 1983 |
Cytosolic free calcium changes induced by chemotactic peptide in neutrophils from patients with chronic granulomatous disease.
Topics: Calcium; Cytosol; Granulomatous Disease, Chronic; Humans; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils | 1984 |
Endogenous protein phosphorylation by resting and activated human neutrophils.
Topics: Digitonin; Granulomatous Disease, Chronic; Humans; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phosphoproteins; Phosphorylation; Tetradecanoylphorbol Acetate; Zymosan | 1983 |
Human neutrophil heterogeneity identified using flow microfluorometry to monitor membrane potential.
Topics: Calcium; Cell Membrane; Flow Cytometry; Granulomatous Disease, Chronic; Humans; Magnesium; Membrane Potentials; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Tetradecanoylphorbol Acetate | 1981 |
Chronic neutropenia and defect in superoxide generation of granulocytes in two patients: enhancement of bactericidal capacity and respiratory burst activity by treatment with recombinant human granulocyte colony-stimulating factor.
Topics: Blood Bactericidal Activity; Child; Colony-Forming Units Assay; Cytotoxicity, Immunologic; Female; Granulocyte Colony-Stimulating Factor; Granulocytes; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Infant; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phagocytosis; Recombinant Proteins; Respiratory Burst; Staphylococcus aureus; Superoxides | 1995 |
Activation of NADPH oxidase of human neutrophils involves the phosphorylation and the translocation of cytosolic p67phox.
Topics: Cytosol; Enzyme Activation; Granulomatous Disease, Chronic; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Reference Values; Tetradecanoylphorbol Acetate | 1993 |
Chemotactic peptide-induced cytoplasmic pH changes in incubated human monocytes.
Topics: Calcium; Cytoplasm; Deoxyglucose; Fluoresceins; Granulomatous Disease, Chronic; Humans; Hydrogen-Ion Concentration; Monocytes; N-Formylmethionine Leucyl-Phenylalanine | 1993 |
Improvement of superoxide production in monocytes from patients with chronic granulomatous disease by recombinant cytokines.
Topics: Cells, Cultured; Cytokines; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Granulomatous Disease, Chronic; Humans; Interferon-gamma; Interleukin-1; Interleukin-3; Male; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Mechanisms of NADPH oxidase activation in human neutrophils: p67phox is required for the translocation of rac 1 but not of rac 2 from cytosol to the membranes.
Topics: Blotting, Western; Cell Membrane; Concanavalin A; Cytoplasm; Granulomatous Disease, Chronic; GTP-Binding Proteins; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; rac GTP-Binding Proteins; Tetradecanoylphorbol Acetate | 1995 |
Deficiency of p67phox, p47phox or gp91phox in chronic granulomatous disease does not impair leucocyte chemotaxis or motility.
Topics: Adult; Blotting, Western; Cell Movement; Chemotaxis, Leukocyte; Female; Granulomatous Disease, Chronic; Humans; Male; Membrane Glycoproteins; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Phosphoproteins | 1997 |
An in-frame triplet deletion within the gp91-phox gene in an adult X-linked chronic granulomatous disease patient with residual NADPH-oxidase activity.
Topics: Adult; Amino Acid Sequence; Antibodies; Bacterial Infections; Cytochrome b Group; Exons; Fatal Outcome; Female; Genetic Carrier Screening; Granulocytes; Granulomatous Disease, Chronic; Heme; Humans; Male; Membrane Glycoproteins; Models, Structural; Molecular Sequence Data; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Pedigree; Peptide Fragments; Polymorphism, Genetic; Protein Conformation; Sequence Deletion; Superoxides; Tetradecanoylphorbol Acetate; X Chromosome; Zymosan | 1997 |
Regulation of capacitative Ca2+ influx in human neutrophil granulocytes. Alterations in chronic granulomatous disease.
Topics: Calcium; Granulomatous Disease, Chronic; Humans; Ion Transport; Manganese; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Molecular and functional characterization of a new X-linked chronic granulomatous disease variant (X91+) case with a double missense mutation in the cytosolic gp91phox C-terminal tail.
Topics: Cell Membrane; Cytochrome b Group; Cytosol; Flavin-Adenine Dinucleotide; Granulomatous Disease, Chronic; Humans; Infant; Male; Membrane Glycoproteins; Mutation, Missense; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Polymorphism, Single-Stranded Conformational; RNA, Messenger; Tetradecanoylphorbol Acetate | 2002 |
Activation of NADPH oxidase in human neutrophils permeabilized with Staphylococcus aureus alpha-toxin. A lower Km when the enzyme is activated in situ.
Topics: Adenosine Triphosphate; Adult; Bacterial Toxins; Cell Membrane; Cell Membrane Permeability; Cytochalasin B; Enzyme Activation; Granulomatous Disease, Chronic; Guanosine 5'-O-(3-Thiotriphosphate); Hemolysin Proteins; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Staphylococcus aureus; Superoxides | 1992 |
Potency of antileukoprotease and alpha 1-antitrypsin to inhibit degradation of fibrinogen by adherent polymorphonuclear leukocytes from normal subjects and patients with chronic granulomatous disease.
Topics: alpha 1-Antitrypsin; Cytochalasin B; Fibrinogen; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Peroxidase; Proteinase Inhibitory Proteins, Secretory; Proteins; Serine Proteinase Inhibitors; Tumor Necrosis Factor-alpha | 1992 |
Leukocyte adhesion-deficient neutrophils fail to amplify phagocytic function in response to stimulation. Evidence for CD11b/CD18-dependent and -independent mechanisms of phagocytosis.
Topics: Antibodies, Monoclonal; Antigens, CD; CD18 Antigens; Complement C4b; Granulomatous Disease, Chronic; Humans; Immunoglobulin G; Leukocyte-Adhesion Deficiency Syndrome; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinases | 1991 |
Leukotriene B4 induced neutrophil functions in chronic granulomatous disease (CGD).
Topics: Calcimycin; Cell Aggregation; Cytochrome b Group; Female; Granulomatous Disease, Chronic; Humans; Kinetics; Leukotriene B4; Male; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Superoxides | 1991 |
Human eosinophils are more toxic than neutrophils in antibody-independent killing.
Topics: Antibody-Dependent Cell Cytotoxicity; Child; Child, Preschool; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Granulomatous Disease, Chronic; Humans; Infant; Killer Cells, Natural; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Neutrophil hyperpolarization in response to a chemotactic peptide.
Topics: Amino Acid Sequence; Calcium; Carbocyanines; Cell Membrane; Choline; Cytosol; Dose-Response Relationship, Drug; Fluorescent Dyes; Granulomatous Disease, Chronic; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Potassium; Potassium Channels; Sodium; Sodium-Potassium-Exchanging ATPase; Thiobarbiturates | 1990 |
Difference in changes of membrane fluidity of polymorphonuclear leukocytes stimulated with phorbol myristate acetate and formyl-methionyl-leucyl-phenylalanine: role of excited oxygen species.
Topics: Adult; Cell Membrane; Granulomatous Disease, Chronic; Humans; Membrane Fluidity; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Enhancement of normal neutrophil chemiluminescence by chronic granulomatous disease neutrophils.
Topics: Acridines; Adolescent; Child; Female; Granulomatous Disease, Chronic; Humans; Luminescent Measurements; Luminol; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reference Values; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Wheat Germ Agglutinins | 1989 |
The 47-kDa protein involved in the NADPH:O2 oxidoreductase activity of human neutrophils is phosphorylated by cyclic AMP-dependent protein kinase without induction of a respiratory burst.
Topics: Bucladesine; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Granulomatous Disease, Chronic; Humans; Isoelectric Focusing; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phosphoproteins; Phosphorylation; Protein Kinases | 1988 |
Modulation of neutrophil-reduced pyridine nucleotide content following stimulation with phorbol myristate acetate and chemotactic factors.
Topics: Complement C5; Complement C5a; Cytochalasin B; Dose-Response Relationship, Drug; Granulomatous Disease, Chronic; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophils; Oxidation-Reduction; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Neutrophil granules in health and disease.
Topics: Chediak-Higashi Syndrome; Exocytosis; Granulomatous Disease, Chronic; Humans; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Receptors, Complement; Receptors, Complement 3b; Receptors, Drug | 1986 |
Ascorbic acid neutralizes reactive oxidants released by hyperactive phagocytes from cigarette smokers.
Topics: Adolescent; Adult; Ascorbic Acid; Child; Female; Granulomatous Disease, Chronic; Humans; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; Phagocytes; Smoking | 1988 |
Detection of carriers of the autosomal form of chronic granulomatous disease.
Topics: Genetic Carrier Screening; Granulomatous Disease, Chronic; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Oxygen Consumption; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Purified protein kinase C phosphorylates a 47-kDa protein in control neutrophil cytoplasts but not in neutrophil cytoplasts from patients with the autosomal form of chronic granulomatous disease.
Topics: Chromosome Aberrations; Chromosome Disorders; Electrophoresis, Polyacrylamide Gel; Granulomatous Disease, Chronic; Humans; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Relationship of protein phosphorylation to the activation of the respiratory burst in human neutrophils. Defects in the phosphorylation of a group of closely related 48-kDa proteins in two forms of chronic granulomatous disease.
Topics: Blood Proteins; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Kinetics; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phosphorus Radioisotopes; Phosphorylation; Tetradecanoylphorbol Acetate | 1988 |