n-formylmethionine leucyl-phenylalanine has been researched along with Acute Promyelocytic Leukemia in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (17.46) | 18.7374 |
| 1990's | 50 (79.37) | 18.2507 |
| 2000's | 1 (1.59) | 29.6817 |
| 2010's | 1 (1.59) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavanagh, SL; Cochrane, CG; Prossnitz, ER; Quehenberger, O; Ye, RD | 2 |
| Brown, V; Chazot, PL; Comer, D; Dib, K; Ennis, M; Jenei, V; Katebe, M; McFarlane, C; Perecko, T; Scheithauer, T; Thurmond, RL | 1 |
| Suchard, SJ | 1 |
| Belanger, KA; Braggins, C; Packman, CH; Phatak, PD; Sham, RL | 1 |
| Bast, A; Ching, TL; Koelemij, JG | 1 |
| Seifert, R; Wenzel-Seifert, K | 1 |
| Watts, RG | 1 |
| Banford, PC; Elliott, KR; Murray, KJ | 1 |
| Jove, R; Nairn, R; Suchard, SJ; Yu, H | 1 |
| Belanger, KA; Packman, CH; Phatak, PD; Sham, RL | 1 |
| Bourne, HR; Homma, Y; Iiri, T; Katada, T; Ohoka, Y; Robishaw, JD | 1 |
| Bouillon, T; Gierschik, P; Jakobs, KH | 1 |
| Coburn, JP; Eggleton, P; Ghebrehiwet, B; Sastry, KN; Tauber, AI; Zaner, KS | 1 |
| Narayanan, R; Rosen, CA; Sartorelli, AC; Sokoloski, JA | 1 |
| Evangelista, V; Locati, M; Luini, W; Mantovani, A; Sozzani, S; Zhou, D | 1 |
| Harnett, MM; Paul, A; Stewart, A; Wakelam, MJ | 1 |
| Baker, M; Brockhausen, I; Culliton, R; Cyopick, P; Mills, GB; Sutherland, DR | 1 |
| Cochrane, CG; Prossnitz, ER; Quehenberger, O; Ye, RD | 1 |
| Höer, A; Klinker, JF; Offermanns, S; Schwaner, I; Seifert, R; Wenzel-Seifert, K | 1 |
| Jakobs, KH; Kupprion, C; Wieland, T | 1 |
| McLeish, KR; Schepers, TM | 1 |
| Erbeck, K; Klein, JB; McLeish, KR | 1 |
| Arellano, R; Grinstein, S | 1 |
| Bianchini, L; Grinstein, S; Todderud, G | 1 |
| Boulay, F; Brouchon, L; Mery, L; Tardif, M | 1 |
| Conigrave, AD; Luttrell, BM; Morris, MB; Rakyan, V; van der Weyden, L | 1 |
| Bayer, C; Hadjokas, N; Nielson, CP | 1 |
| Klein, JB; McLeish, KR; Scherzer, JA | 1 |
| Hruska, KA; Malone, JD; Nishii, Y; Seino, Y; Tanaka, H; Teitelbaum, SL | 1 |
| Berger, M; Cowen, DS; Dubyak, GR; Nuttle, L | 1 |
| Laskin, DL; Laskin, JD; Sirak, AA | 1 |
| Klein, JB; McLeish, KR; Sonnenfeld, G | 1 |
| Di Virgilio, F; Lew, DP; Monod, A; Pittet, D; Pozzan, T | 1 |
| Honma, Y; Hozumi, M; Nakamaki, T; Sakashita, A; Tsuruoka, N | 1 |
| Evans, JF; Kargman, S; Prasit, P | 1 |
| Caon, AC; Chouinard, G; Gilbert, C; McColl, SR; Naccache, PH | 1 |
| Dazin, PF; Mitsuhashi, M; Mitsuhashi, T; Payan, DG | 1 |
| Leaver, HA; Qu, JM; Wilson, NH; Yap, PL | 1 |
| Gierschik, P; Jakobs, KH; Ulibarri, I; Wieland, T | 1 |
| Dieterich, K; Gierschik, P; Jakobs, KH; Moghtader, R; Straub, C | 1 |
| Dubyak, GR; Jacobs, LS; Xie, MS | 1 |
| Bohse, C; Elson, EL; Erzurum, SC; Kus, ML; Worthen, GS | 1 |
| Cockcroft, S; Stutchfield, J | 1 |
| Kinkade, JM; Merrill, AH; Owens, NE; Stevens, VL; Winton, EF | 1 |
| Austinhirst, R; Snyder, F; Vallari, DS | 1 |
| Bitran, JA; Daly, JW; Gusovsky, F; Yasumoto, T | 1 |
| Aviram, A; Rephaeli, A; Shaklai, M | 1 |
| Laskin, DL; Laskin, JD; Robertson, FM; Sirak, AA | 1 |
| Boulay, F; Brouchon, L; Tardif, M; Vignais, P | 1 |
| Baker, B; Cowen, DS; Dubyak, GR | 1 |
| Bernardo, J; Brennan, L; Bresnick, SA; Brink, HF; Newburger, PE; Simons, ER; Weil, G | 1 |
| Jungblut, P; Schultz, G; Seifert, R | 1 |
| Iiri, T; Katada, T; Morishima, N; Ohoka, Y; Tohkin, M; Ui, M | 1 |
| Gierschik, P; Jakobs, KH; Sidiropoulos, D | 1 |
| Nath, J; Powledge, A; Wright, DG | 1 |
| Böhme, E; Schmidt, HH; Seifert, R | 1 |
| Lew, DP; Mayr, GW; Monod, A; Pittet, D; Schlegel, W | 1 |
| Mitsuhashi, M; Mitsuhashi, T; Payan, DG | 1 |
| Damais, C; Frelin, C; Krawice, I; Ladoux, A | 1 |
| Cohen, HJ; Currie, MS; Rao, KM; Ruff, JC | 1 |
| Cowen, DS; Dubyak, GR; Meuller, LM | 1 |
| Cotter, TG; Meagher, LC | 1 |
63 other study(ies) available for n-formylmethionine leucyl-phenylalanine and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
Multiple domains of the N-formyl peptide receptor are required for high-affinity ligand binding. Construction and analysis of chimeric N-formyl peptide receptors.
Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium; Fluorescent Antibody Technique; Genetic Vectors; Humans; Kinetics; L Cells; Leukemia, Promyelocytic, Acute; Ligands; Mice; Models, Structural; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Protein Structure, Secondary; Radioligand Assay; Receptors, Formyl Peptide; Receptors, Immunologic; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Transfection; Tumor Cells, Cultured | 1993 |
The histamine H4 receptor is a potent inhibitor of adhesion-dependent degranulation in human neutrophils.
Topics: Cell Adhesion; Cell Degranulation; Cell Line, Tumor; Cell Shape; Cells, Cultured; Cytochalasin B; Fibrinogen; Histamine; Humans; Indoles; Leukemia, Promyelocytic, Acute; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen; MAP Kinase Signaling System; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oximes; p38 Mitogen-Activated Protein Kinases; Piperazines; Piperidines; Protein Conformation; Pyridines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; RNA, Messenger | 2014 |
Interaction of human neutrophils and HL-60 cells with the extracellular matrix.
Topics: Cell Adhesion; Cell Line; Cells, Cultured; Chemotaxis, Leukocyte; Cytochalasin B; Extracellular Matrix; Extracellular Matrix Proteins; Fibronectins; Gelatinases; Glycoproteins; Humans; Kinetics; Laminin; Leukemia, Promyelocytic, Acute; Membrane Glycoproteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Thrombospondins; Tumor Cells, Cultured; Vitronectin | 1993 |
Functional characteristics of mature granulocytes in a patient with acute promyelocytic leukemia treated with all-trans retinoic acid.
Topics: Actins; Antigens, Surface; Calcium; Cell Adhesion Molecules; Cell Size; Granulocytes; Humans; Immunophenotyping; In Vitro Techniques; Integrins; Interleukin-8; L-Selectin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Tretinoin | 1995 |
The effect of histamine on the oxidative burst of HL60 cells before and after exposure to reactive oxygen species.
Topics: Bucladesine; Calcium; Cell Differentiation; Histamine; Humans; Hydrogen-Ion Concentration; Leukemia, Promyelocytic, Acute; Mast Cells; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reactive Oxygen Species; Respiratory Burst; Superoxides; Tumor Cells, Cultured | 1995 |
Partial inhibition of human neutrophil activation by FK-506 at supratherapeutic concentrations.
Topics: Adult; Calcimycin; Calcium; Cyclosporine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Promyelocytic, Acute; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tacrolimus; Tumor Cells, Cultured | 1993 |
Role of gelsolin in the formation and organization of triton-soluble F-actin during myeloid differentiation of HL-60 cells.
Topics: Actins; Biopolymers; Cell Compartmentation; Cell Differentiation; Chemotaxis, Leukocyte; Contractile Proteins; Cytoskeleton; Dimethyl Sulfoxide; Filamins; Gelsolin; Humans; Leukemia, Promyelocytic, Acute; Microfilament Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Proteins; Octoxynol; Respiratory Burst; Solubility; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Chemotactic peptide mediated cAMP production is inhibited by adenosine deaminase in HL60 cell granulocytes.
Topics: Adenosine Deaminase; Cell Line; Cyclic AMP; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Tumor Cells, Cultured | 1995 |
Dissociation of mitogen-activated protein kinase activation from the oxidative burst in differentiated HL-60 cells and human neutrophils.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP; Enzyme Activation; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Functional properties of HL60 cells matured with all-trans-retinoic acid and DMSO: differences in response to interleukin-8 and fMLP.
Topics: Actins; Cell Differentiation; Chemotaxis, Leukocyte; Dimethyl Sulfoxide; Granulocytes; Humans; Interleukin-8; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Nitroblue Tetrazolium; Oxidation-Reduction; Tretinoin; Tumor Cells, Cultured | 1995 |
Potentiation of Gi-mediated phospholipase C activation by retinoic acid in HL-60 cells. Possible role of G gamma 2.
Topics: Cell Differentiation; Cell Line; Cell Membrane; Chromatography, Affinity; Dimethyl Sulfoxide; Drug Synergism; Enzyme Activation; Gene Expression; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Immunoblotting; Kinetics; Leukemia, Promyelocytic, Acute; Macromolecular Substances; N-Formylmethionine Leucyl-Phenylalanine; Tretinoin; Tumor Cells, Cultured; Type C Phospholipases | 1995 |
Receptor-stimulated hydrolysis of guanosine 5'-triphosphate in membrane preparations.
Topics: Adenosine Diphosphate Ribose; Cell Line; Cell Membrane; Cholera Toxin; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Indicators and Reagents; Kinetics; Leukemia, Promyelocytic, Acute; Macromolecular Substances; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorus Radioisotopes; Radioisotope Dilution Technique; Receptors, Cell Surface; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1994 |
Characterization of the human neutrophil C1q receptor and functional effects of free ligand on activated neutrophils.
Topics: Antibodies; Blotting, Western; Carrier Proteins; Cell Differentiation; Cell Membrane; Complement C1q; Humans; Hyaluronan Receptors; In Vitro Techniques; Kinetics; Leukemia, Promyelocytic, Acute; Macrophage-1 Antigen; Membrane Glycoproteins; Mitochondrial Proteins; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Complement; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1994 |
Antisense oligonucleotides to the p65 subunit of NF-kappa B block CD11b expression and alter adhesion properties of differentiated HL-60 granulocytes.
Topics: Antigens, CD; Base Sequence; CD11 Antigens; Cell Adhesion; Cell Differentiation; Dimethyl Sulfoxide; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NF-kappa B; Oligonucleotides, Antisense; Phosphates; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Rapid induction of arachidonic acid release by monocyte chemotactic protein-1 and related chemokines. Role of Ca2+ influx, synergism with platelet-activating factor and significance for chemotaxis.
Topics: Arachidonic Acid; Calcimycin; Calcium; Cell Line; Chemokine CCL2; Chemotactic Factors; Chemotaxis, Leukocyte; Cytokines; Egtazic Acid; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Recombinant Proteins; Structure-Activity Relationship; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1994 |
Changes in the activities and cellular localisation of phospholipases in differentiating HL-60 cells.
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipase D; Phospholipases; Phospholipases A; Phosphoric Diester Hydrolases; Subcellular Fractions; Tumor Cells, Cultured | 1993 |
Role of aberrant sialylation of chronic myeloid leukemia granulocytes on binding and signal transduction by chemotactic peptides and colony stimulating factors.
Topics: Calcium; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; N-Acetylneuraminic Acid; N-Formylmethionine Leucyl-Phenylalanine; Sialic Acids; Signal Transduction; Tumor Cells, Cultured | 1993 |
Signal transducing properties of the N-formyl peptide receptor expressed in undifferentiated HL60 cells.
Topics: Actins; Calcium; Cell Differentiation; Gene Expression; GTP-Binding Proteins; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Signal Transduction; Transfection; Tumor Cells, Cultured | 1993 |
Lipopeptides activate Gi-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Bucladesine; Cell Differentiation; Cell Line; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Lipoproteins; Membrane Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Superoxides; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Receptor-stimulated dissociation of GTP[S] from Gi-proteins in membranes of HL-60 cells.
Topics: Binding Sites; Cell Differentiation; Cell Membrane; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Differential cholera-toxin- and pertussis-toxin-catalysed ADP-ribosylation of G-proteins coupled to formyl-peptide and leukotriene B4 receptors.
Topics: Adenosine Diphosphate Ribose; Cholera Toxin; GTP-Binding Proteins; Guanosine Diphosphate; Guanylyl Imidodiphosphate; Humans; Leukemia, Promyelocytic, Acute; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; NAD; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Leukotriene B4; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Differential uncoupling of chemoattractant receptors from G proteins in retinoic acid-differentiated HL-60 granulocytes.
Topics: Cell Differentiation; Dimethyl Sulfoxide; Granulocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Leukotriene B4; Superoxides; Tretinoin; Tumor Cells, Cultured | 1993 |
Role of isoprenylation in intracellular pH regulation of granulocytes.
Topics: Granulocytes; GTP-Binding Proteins; Humans; Hydrogen-Ion Concentration; Kinetics; Leukemia, Promyelocytic, Acute; Lovastatin; Mevalonic Acid; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Protein Prenylation; Tumor Cells, Cultured | 1993 |
Cytosolic [Ca2+] homeostasis and tyrosine phosphorylation of phospholipase C gamma 2 in HL60 granulocytes.
Topics: Amino Acid Sequence; Biological Transport; Calcium; Calcium-Transporting ATPases; Cytosol; Homeostasis; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Leukemia, Promyelocytic, Acute; Manganese; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Terpenes; Thapsigargin; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vanadates | 1993 |
Agonist-dependent phosphorylation of N-formylpeptide and activation peptide from the fifth component of C (C5a) chemoattractant receptors in differentiated HL60 cells.
Topics: Amino Acid Sequence; beta-Adrenergic Receptor Kinases; Complement C5a; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Kinases; Receptor, Anaphylatoxin C5a; Receptors, Complement; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Extracellular ATP couples to cAMP generation and granulocytic differentiation in human NB4 promyelocytic leukaemia cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Antigens, CD; Blotting, Northern; Cell Differentiation; Cell Size; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Granulocytes; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Phosphodiesterase Inhibitors; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Thionucleotides; Tretinoin; Tumor Cells, Cultured | 2000 |
Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; DNA Probes; DNA, Neoplasm; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Mice; Molecular Sequence Data; Molecular Weight; Multigene Family; N-Formylmethionine Leucyl-Phenylalanine; Poly A; Polymerase Chain Reaction; Protein Conformation; Receptors, Formyl Peptide; Receptors, Immunologic; RNA; RNA, Messenger; Sequence Homology, Nucleic Acid; Transfection | 1992 |
Impaired stimulus-response coupling in association with increased growth rate of HL60 cells.
Topics: Calcium; Cell Division; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Respiratory Burst; Tumor Cells, Cultured | 1992 |
IFN-gamma enhances expression of formyl peptide receptors and guanine nucleotide-binding proteins by HL-60 granulocytes.
Topics: Cell Differentiation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Interferon-gamma; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Tumor Cells, Cultured | 1992 |
Disassociation of the macrophage-maturational effects of vitamin D from respiratory burst priming.
Topics: Antineoplastic Agents; Calcitriol; Calcium; Cell Differentiation; Cell Line; Cytoplasm; Humans; Leukemia, Promyelocytic, Acute; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Calcitriol; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Steroid; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Chronic treatment with P2-purinergic receptor agonists induces phenotypic modulation of the HL-60 and U937 human myelogenous leukemia cell lines.
Topics: Actins; Adenosine; Adenosine Triphosphate; Calcium; Cell Differentiation; Cell Division; Cell Line; Genes, myc; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Lymphoma, Large B-Cell, Diffuse; N-Formylmethionine Leucyl-Phenylalanine; Phagocytes; Phenotype; Receptors, Purinergic; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate; Uridine Triphosphate | 1991 |
Differentiation of HL-60 myeloid leukaemia cells is associated with a transient block in the G2 phase of the cell cycle.
Topics: Acridine Orange; Bucladesine; Cell Cycle; Cell Differentiation; Cell Line; Demecolcine; G2 Phase; Humans; Hydrogen Peroxide; Hydroxyurea; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; RNA, Neoplasm; Vinblastine | 1991 |
Priming of the HL-60 cell respiratory burst response by tumor necrosis factor-alpha.
Topics: Cell Differentiation; Cell Line; Cycloheximide; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Recombinant Proteins; Superoxides; Tumor Necrosis Factor-alpha | 1991 |
Correlation between plasma membrane potential and second messenger generation in the promyelocytic cell line HL-60.
Topics: Calcium; Cell Line; Cell Membrane; Cytosol; Dimethyl Sulfoxide; Egtazic Acid; Gramicidin; Humans; Inositol 1,4,5-Trisphosphate; Ionomycin; Kinetics; Leukemia, Promyelocytic, Acute; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Ouabain; Potassium Chloride; Second Messenger Systems; Tretinoin; Tumor Cells, Cultured | 1990 |
Granulocyte colony-stimulating factor, not granulocyte-macrophage colony-stimulating factor, co-operates with retinoic acid on the induction of functional N-formyl-methionyl-phenylalanine receptors in HL-60 cells.
Topics: Cell Differentiation; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Nitroblue Tetrazolium; Receptors, Formyl Peptide; Receptors, Immunologic; Thymidine; Tretinoin; Tumor Cells, Cultured | 1991 |
Translocation of HL-60 cell 5-lipoxygenase. Inhibition of A23187- or N-formyl-methionyl-leucyl-phenylalanine-induced translocation by indole and quinoline leukotriene synthesis inhibitors.
Topics: Arachidonate 5-Lipoxygenase; Calcimycin; Cell Differentiation; Cell Line; Cell Membrane; Dimethyl Sulfoxide; Humans; Indoles; Kinetics; Leukemia, Promyelocytic, Acute; Leukotriene Antagonists; Leukotrienes; N-Formylmethionine Leucyl-Phenylalanine; Quinolines; Subcellular Fractions | 1991 |
Pertussis toxin selectively interferes with the responses of the HL-60 human promyelocytic cell line to dimethylsulfoxide.
Topics: Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; RNA, Messenger; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1991 |
Agonistic activities of histamine-albumin conjugates at histamine H2 receptors on human HL-60 promyelocytic leukemia cells.
Topics: Albumins; Calcium; Flow Cytometry; Histamine; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Histamine H2; Tumor Cells, Cultured | 1991 |
Kinetics of calcium mobilisation and inositol phosphate metabolism in endotoxin-stimulated HL-60 cells.
Topics: Calcium; Cell Line; Endotoxins; Fluorescent Dyes; Fura-2; Humans; Inositol Phosphates; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Salmonella; Spectrometry, Fluorescence | 1991 |
Activation of signal-transducing guanine-nucleotide-binding regulatory proteins by guanosine 5'-[gamma-thio]triphosphate. Information transfer by intermediately thiophosphorylated beta gamma subunits.
Topics: Animals; Cattle; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Signal Transduction; Tumor Cells, Cultured | 1991 |
Signal amplification in HL-60 granulocytes. Evidence that the chemotactic peptide receptor catalytically activates guanine-nucleotide-binding regulatory proteins in native plasma membranes.
Topics: Adenosine Diphosphate Ribose; Cell Membrane; Granulocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Leukemia, Promyelocytic, Acute; Magnesium; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Sodium Chloride; Tumor Cells, Cultured | 1991 |
Regulation of phospholipase D and primary granule secretion by P2-purinergic- and chemotactic peptide-receptor agonists is induced during granulocytic differentiation of HL-60 cells.
Topics: Adenosine Triphosphate; Cell Differentiation; Cytochalasin B; Cytoplasmic Granules; Enzyme Activation; Ethanol; GTP-Binding Proteins; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidic Acids; Phospholipase D; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Purinergic; Tumor Cells, Cultured | 1991 |
Mechanical properties of HL60 cells: role of stimulation and differentiation in retention in capillary-sized pores.
Topics: Actin Cytoskeleton; Actins; Biophysical Phenomena; Biophysics; Cell Adhesion; Cell Differentiation; Cytochalasin D; Filtration; Humans; Leukemia, Promyelocytic, Acute; Microcirculation; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Tumor Cells, Cultured | 1991 |
Characterization of fMet-Leu-Phe-stimulated phospholipase C in streptolysin-O-permeabilised cells.
Topics: Adenosine Triphosphate; Bacterial Proteins; Calcium; Cell Line; Cell Membrane; Cell Membrane Permeability; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Streptolysins; Type C Phospholipases; Virulence Factors, Bordetella | 1991 |
Modulation of retinoic acid-induced differentiation of human leukemia (HL-60) cells by serum factors and sphinganine.
Topics: Blood Physiological Phenomena; Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Sphingosine; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin | 1990 |
Development of specific functionally active receptors for platelet-activating factor in HL-60 cells following granulocytic differentiation.
Topics: Acetylglucosaminidase; Binding, Competitive; Cell Differentiation; Cytochalasin B; Dimethyl Sulfoxide; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tumor Cells, Cultured | 1990 |
Mechanism of maitotoxin-stimulated phosphoinositide breakdown in HL-60 cells.
Topics: Calcium; Egtazic Acid; Guanosine Triphosphate; Humans; Ionomycin; Leukemia, Promyelocytic, Acute; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; Oxocins; Phosphatidylinositols; Tumor Cells, Cultured; Type C Phospholipases | 1990 |
The role of increased calcium influx rate in receptor mediated function of differentiating HL-60 cells.
Topics: Bucladesine; Calcium; Cell Differentiation; Cholera Toxin; Concanavalin A; Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Tretinoin; Tumor Cells, Cultured | 1990 |
Failure of F-Met-Leu-Phe to induce chemotaxis in differentiated promyelocytic (HL-60) leukemia cells.
Topics: Antigens, Surface; Bucladesine; Butyrates; Cell Differentiation; Cell Division; Chemotaxis, Leukocyte; Colforsin; Dinoprostone; Humans; Hydrogen Peroxide; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Tumor Cells, Cultured | 1990 |
The human N-formylpeptide receptor. Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bucladesine; Cell Line; Cell Membrane; Cloning, Molecular; DNA, Neoplasm; Gene Library; GTP-Binding Proteins; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Molecular Weight; Multigene Family; N-Formylmethionine Leucyl-Phenylalanine; Protein Conformation; Receptors, Formyl Peptide; Receptors, Immunologic; Restriction Mapping; Sequence Homology, Nucleic Acid; Transfection | 1990 |
Pertussis toxin produces differential inhibitory effects on basal, P2-purinergic, and chemotactic peptide-stimulated inositol phospholipid breakdown in HL-60 cells and HL-60 cell membranes.
Topics: Cell Differentiation; Cell Line; Cell Membrane; Granulocytes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Inositol Phosphates; Kinetics; Leukemia, Promyelocytic, Acute; Membrane Lipids; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Thionucleotides; Type C Phospholipases; Uridine Triphosphate; Virulence Factors, Bordetella | 1990 |
Simultaneous flow cytometric measurements of cytoplasmic Ca++ and membrane potential changes upon FMLP exposure as HL-60 cells mature into granulocytes: using [Ca++]in as an indicator of granulocyte maturity.
Topics: Calcium; Cell Differentiation; Dimethylformamide; Flow Cytometry; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Tumor Cells, Cultured | 1990 |
Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells.
Topics: Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Cell Differentiation; Cell Line; Cytosol; Dimethyl Sulfoxide; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hexachlorocyclohexane; Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Superoxides; Tetradecanoylphorbol Acetate; Thionucleotides | 1989 |
Chemotactic peptide receptor-supported ADP-ribosylation of a pertussis toxin substrate GTP-binding protein by cholera toxin in neutrophil-type HL-60 cells.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; ADP-Ribosylation Factors; Animals; Brain; Carrier Proteins; Cattle; Cell Differentiation; Cell Line; Cell Membrane; Cholera Toxin; Cytosol; GTP-Binding Proteins; Guanine Nucleotides; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Virulence Factors, Bordetella | 1989 |
Two distinct Gi-proteins mediate formyl peptide receptor signal transduction in human leukemia (HL-60) cells.
Topics: Adenosine Diphosphate Ribose; Cell Line; Cell Membrane; Cholera Toxin; GTP-Binding Proteins; Humans; Leukemia, Promyelocytic, Acute; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; NAD; Peptide Mapping; Receptors, Formyl Peptide; Receptors, Immunologic; Signal Transduction; Tumor Cells, Cultured | 1989 |
Studies of signal transduction in the respiratory burst-associated stimulation of fMet-Leu-Phe-induced tubulin tyrosinolation and phorbol 12-myristate 13-acetate-induced posttranslational incorporation of tyrosine into multiple proteins in activated neutr
Topics: Cell Line; Diglycerides; Humans; In Vitro Techniques; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Kinase C; Protein Processing, Post-Translational; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Tubulin; Tyrosine | 1989 |
Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4.
Topics: Bucladesine; Calcitriol; Canavanine; Cell Line; Humans; In Vitro Techniques; Kinetics; Leukemia, Promyelocytic, Acute; Leukotriene B4; Luminescence; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Platelet Activating Factor | 1989 |
Chemoattractant receptor promotion of Ca2+ influx across the plasma membrane of HL-60 cells. A role for cytosolic free calcium elevations and inositol 1,3,4,5-tetrakisphosphate production.
Topics: Aminoquinolines; Biological Transport; Calcium; Calcium Channels; Cell Membrane; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Isomerism; Kinetics; Leukemia, Promyelocytic, Acute; Microscopy, Fluorescence; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sugar Phosphates; Tumor Cells, Cultured | 1989 |
Multiple signaling pathways of histamine H2 receptors. Identification of an H2 receptor-dependent Ca2+ mobilization pathway in human HL-60 promyelocytic leukemia cells.
Topics: Calcium; Calcium Channel Blockers; Cell Differentiation; Cholera Toxin; Colforsin; Cyclic AMP; Dimethyl Sulfoxide; Dinoprostone; Histamine; Humans; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Histamine H2; Signal Transduction; Tumor Cells, Cultured | 1989 |
Phorbol esters and chemotactic factor induce distinct changes in cytoplasmic Ca2+ and pH in granulocytic like HL60 cells.
Topics: Amiloride; Calcium; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Granulocytes; Humans; Hydrogen-Ion Concentration; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Lack of correlation between induction of chemotactic peptide receptors and stimulus-induced actin polymerization in HL-60 cells treated with dibutyryl cyclic adenosine monophosphate or retinoic acid.
Topics: Actins; Bucladesine; Cell Cycle; Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Polymers; Receptors, Formyl Peptide; Receptors, Immunologic; Tretinoin; Tumor Cells, Cultured | 1988 |
Activation of inositol phospholipid breakdown in HL60 cells by P2-purinergic receptors for extracellular ATP. Evidence for mediation by both pertussis toxin-sensitive and pertussis toxin-insensitive mechanisms.
Topics: Adenosine Triphosphate; Calcium; Cell Line; Cytosol; Humans; Inositol Phosphates; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Phosphatidylinositols; Receptors, Purinergic; Sodium Chloride; Sodium Fluoride; Sugar Phosphates; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
The degranulation response in differentiated HL-60 cells.
Topics: Calcimycin; Cell Differentiation; Cell Line; Cytoplasmic Granules; Granulocytes; Humans; Immunoglobulin G; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Pancreatic Elastase; Peroxidase; Tetradecanoylphorbol Acetate | 1988 |