Compounds > n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine
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n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine and Muscle Relaxation

n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine has been researched along with Muscle Relaxation in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (75.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atwal, KS; Bryson, CC; Cohen, RB; Dickinson, KE; Grover, GJ; Lodge, NJ; Normandin, DE; Sleph, PG; Traeger, SC1
Brune, ME; Buckner, SA; Carroll, WA; Castle, NA; Coghlan, MJ; Davis-Taber, R; Daza, AV; Fabiyi, A; Fey, T; Gopalakrishnan, M; London, B; Milicic, I; Printzenhoff, D; Scott, VE; Shieh, CC; Sullivan, JP; Turner, SC; Whiteaker, KL1
Antonaccio, MJ; Dzwonczyk, S; Grover, GJ; Normandin, D; Sargent, CA; Sleph, PG1
Linde, C; Quast, U1
Linde, C; Löffler, C; Quast, U1
Kessler, C; Linde, C; Löffler, C; Quast, U1
Brioni, JD; Buckner, SA; Cain, JC; Davis-Taber, R; Gopalakrishnan, M; Milicic, I; Molinari, EJ; Postl, S; Scott, VE; Shieh, CC; Sullivan, JP; Whiteaker, KL1
Brioni, JD; Buckner, SA; Coghlan, MJ; Feng, J; Gopalakrishnan, M; Shieh, CC; Sullivan, JP1

Other Studies

8 other study(ies) available for n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine and Muscle Relaxation

ArticleYear
Binding of ATP-sensitive potassium channel (KATP) openers to cardiac membranes: correlation of binding affinities with cardioprotective and smooth muscle relaxing potencies.
    Journal of medicinal chemistry, 1998, Jan-29, Volume: 41, Issue:3

    Topics: Animals; ATP-Binding Cassette Transporters; Cardiotonic Agents; Dogs; KATP Channels; Muscle Relaxation; Muscle, Smooth; Myocardium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Structure-Activity Relationship

1998
In vitro and in vivo characterization of a novel naphthylamide ATP-sensitive K+ channel opener, A-151892.
    British journal of pharmacology, 2004, Volume: 143, Issue:1

    Topics: Acetamides; Adenosine Triphosphate; Animals; Barbiturates; Binding, Competitive; Blood Pressure; Blood Vessels; Female; Guanidines; Guinea Pigs; In Vitro Techniques; Iodine Radioisotopes; Isoxazoles; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthalenes; Patch-Clamp Techniques; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Swine; Urinary Bladder

2004
Cardioprotective effects of the cyanoguanidine potassium channel opener P-1075.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:4

    Topics: Animals; Aorta, Thoracic; Coronary Circulation; Dose-Response Relationship, Drug; Guanidines; Heart; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Potassium Channels; Pyridines; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Vasodilator Agents; Ventricular Function, Left

1993
Potentiation of P1075-induced K+ channel opening by stimulation of adenylate cyclase in rat isolated aorta.
    British journal of pharmacology, 1995, Volume: 115, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Aorta; Binding, Competitive; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Isoquinolines; Isotope Labeling; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Rubidium; Sulfonamides; Vasodilator Agents

1995
Inhibition by protein kinase C of the 86Rb+ efflux and vasorelaxation induced by P1075, a K(ATP) channel opener, in rat isolated aorta.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:3

    Topics: Adenosine Triphosphate; Animals; Aorta; Enzyme Activation; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Binding; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes; Tetradecanoylphorbol Acetate

1997
Interaction between thiol-modifying agents and P1075, a K(ATP) channel opener, in rat isolated aorta.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:4

    Topics: Animals; Aorta; Dithiothreitol; Endothelium, Vascular; Guanidines; Hydroxymercuribenzoates; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Channels; Protein Binding; Pyridines; Radioactive Tracers; Rats; Rats, Sprague-Dawley; Rubidium; Sulfhydryl Reagents; Thimerosal; Vasodilator Agents

1997
Characterization of the ATP-sensitive potassium channels (KATP) expressed in guinea pig bladder smooth muscle cells.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Fluorescence; Guanidines; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscle Relaxation; Muscle, Smooth; Patch-Clamp Techniques; Potassium Channels; Pyridines; Radioligand Assay; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urinary Bladder; Vasodilator Agents

1999
Functional implication of spare ATP-sensitive K(+) channels in bladder smooth muscle cells.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3

    Topics: Acetylcholine; Amides; Animals; Benzophenones; Drug Interactions; Electrophysiology; Guanidines; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Membrane Proteins; Muscle Relaxation; Muscle, Smooth; Pinacidil; Potassium Channels; Pyridines; Swine; Urinary Bladder; Vasodilator Agents

2001