n-acetyltryptophan has been researched along with Amyotrophic Lateral Sclerosis in 2 studies
N-acetyltryptophan : An N-acetylamino acid that is the N-acetyl derivative of tryptophan.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, W | 2 |
| Fotinos, A | 1 |
| Wu, Q | 1 |
| Chen, Y | 1 |
| Zhu, Y | 1 |
| Baranov, S | 1 |
| Tu, Y | 1 |
| Zhou, EW | 1 |
| Sinha, B | 1 |
| Kristal, BS | 1 |
| Wang, X | 2 |
| Sirianni, AC | 1 |
| Jiang, J | 1 |
| Zeng, J | 1 |
| Mao, LL | 1 |
| Zhou, S | 1 |
| Sugarbaker, P | 1 |
| Zhang, X | 1 |
| Friedlander, RM | 1 |
2 other studies available for n-acetyltryptophan and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
N-acetyl-L-tryptophan delays disease onset and extends survival in an amyotrophic lateral sclerosis transgenic mouse model.
Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Male; Mice; Mice, Transgenic; Mitochondria; Motor | 2015 |
N-acetyl-l-tryptophan, but not N-acetyl-d-tryptophan, rescues neuronal cell death in models of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Caspases; Cell Line; Cytochromes c; Drug Evaluati | 2015 |