n-acetylserotonin has been researched along with Malignant Melanoma in 4 studies
N-acetylserotonin : An N-acylserotonin resulting from the formal condensation of the primary amino group of serotonin with the carboxy group of acetic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of melatonin, N-acetylserotonin and serotonin on the growth and tyrosinase activity of SK-Mel 23 and SK-Mel 28 human melanoma cell lines were investigated." | 7.72 | Melatonin biological activity and binding sites in human melanoma cells. ( Castrucci, AM; Souza, AV; Visconti, MA, 2003) |
| "Indolic and kynuric pathways of skin melatonin metabolism were monitored by liquid chromatography mass spectrometry in human keratinocytes, melanocytes, dermal fibroblasts, and melanoma cells." | 3.79 | Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells. ( Fischer, TW; Janjetovic, Z; Kim, TK; Kleszczynski, K; Li, W; Lin, Z; Reiter, RJ; Slominski, AT; Sweatman, T, 2013) |
| "The effects of melatonin, N-acetylserotonin and serotonin on the growth and tyrosinase activity of SK-Mel 23 and SK-Mel 28 human melanoma cell lines were investigated." | 3.72 | Melatonin biological activity and binding sites in human melanoma cells. ( Castrucci, AM; Souza, AV; Visconti, MA, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamazaki, Y | 1 |
| Kawano, Y | 1 |
| Yamanaka, A | 1 |
| Maruyama, S | 1 |
| Kim, TK | 1 |
| Kleszczynski, K | 1 |
| Janjetovic, Z | 1 |
| Sweatman, T | 2 |
| Lin, Z | 1 |
| Li, W | 1 |
| Reiter, RJ | 1 |
| Fischer, TW | 1 |
| Slominski, AT | 1 |
| Souza, AV | 1 |
| Visconti, MA | 1 |
| Castrucci, AM | 1 |
| Slominski, A | 1 |
| Pisarchik, A | 1 |
| Semak, I | 1 |
| Wortsman, J | 1 |
| Szczesniewski, A | 1 |
| Slugocki, G | 1 |
| McNulty, J | 1 |
| Kauser, S | 1 |
| Tobin, DJ | 1 |
| Jing, C | 1 |
| Johansson, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role of Peripheral Serotonin in Oculocutaneous Albinism[NCT06138509] | 160 participants (Anticipated) | Observational | 2024-01-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for n-acetylserotonin and Malignant Melanoma
| Article | Year |
|---|---|
N-[(Dihydroxyphenyl)acyl]serotonins as potent inhibitors of tyrosinase from mouse and human melanoma cells.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Enz | 2009 |
Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells.
Topics: 5-Methoxytryptamine; Animals; Cell Differentiation; Cell Line; Cell Line, Tumor; Cells, Cultured; Ch | 2013 |
Melatonin biological activity and binding sites in human melanoma cells.
Topics: Binding Sites; Binding, Competitive; Cell Division; Humans; Iodine Radioisotopes; Melanoma; Melatoni | 2003 |
Serotoninergic and melatoninergic systems are fully expressed in human skin.
Topics: Acetylserotonin O-Methyltransferase; Arylamine N-Acetyltransferase; Cell Line; Gene Expression; Gene | 2002 |