Page last updated: 2024-10-19

n-acetylserotonin and Disease Models, Animal

n-acetylserotonin has been researched along with Disease Models, Animal in 7 studies

N-acetylserotonin : An N-acylserotonin resulting from the formal condensation of the primary amino group of serotonin with the carboxy group of acetic acid.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Melatonin and N-acetylserotonin (NAS) are tryptophan metabolites that have potent anti-oxidant, anti-inflammatory and neuroprotective properties in several animal models of neurological injury and disease including multiple sclerosis (MS)."7.83Efficacy of N-Acetylserotonin and Melatonin in the EAE Model of Multiple Sclerosis. ( Ariyannur, PS; Kirmani, BF; Moffett, JR; Namboodiri, AM; Ribeiro, R; Tanaka, M; Wen, J; Zhang, Y, 2016)
"Melatonin and N-acetylserotonin (NAS) are tryptophan metabolites that have potent anti-oxidant, anti-inflammatory and neuroprotective properties in several animal models of neurological injury and disease including multiple sclerosis (MS)."3.83Efficacy of N-Acetylserotonin and Melatonin in the EAE Model of Multiple Sclerosis. ( Ariyannur, PS; Kirmani, BF; Moffett, JR; Namboodiri, AM; Ribeiro, R; Tanaka, M; Wen, J; Zhang, Y, 2016)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Mondanelli, G1
Coletti, A1
Greco, FA1
Pallotta, MT1
Orabona, C1
Iacono, A1
Belladonna, ML1
Albini, E1
Panfili, E1
Fallarino, F1
Gargaro, M1
Manni, G1
Matino, D1
Carvalho, A1
Cunha, C1
Maciel, P1
Di Filippo, M1
Gaetani, L1
Bianchi, R1
Vacca, C1
Iamandii, IM1
Proietti, E1
Boscia, F1
Annunziato, L1
Peppelenbosch, M1
Puccetti, P1
Calabresi, P1
Macchiarulo, A1
Santambrogio, L1
Volpi, C1
Grohmann, U1
Liu, J1
Zhang, N1
Zhang, M1
Yin, H1
Zhang, X1
Wang, X2
Zhao, Y1
Wen, J1
Ariyannur, PS1
Ribeiro, R1
Tanaka, M1
Moffett, JR1
Kirmani, BF1
Namboodiri, AM1
Zhang, Y1
Lima, E1
Cabral, FR1
Cavalheiro, EA1
Naffah-Mazzacoratti, Mda G1
Amado, D1
Klemm, P1
Ostrowski, J1
Morath, T1
Gruber, C1
Martorana, PA1
Henning, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Melatonin on Seizure Outcome, Neuronal Damage and Quality of Life in Patients With Generalized Epilepsy: A Randomized, add-on Placebo-controlled Clinical Trial[NCT03590197]Phase 4104 participants (Actual)Interventional2018-08-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for n-acetylserotonin and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 02-18, Volume: 117, Issue:7

    Topics: Allosteric Regulation; Allosteric Site; Animals; Biocatalysis; Disease Models, Animal; Encephalomyel

2020
N-acetylserotonin alleviated the expression of interleukin-1β in retinal ischemia-reperfusion rats via the TLR4/NF-κB/NLRP3 pathway.
    Experimental eye research, 2021, Volume: 208

    Topics: Animals; Disease Models, Animal; Immunohistochemistry; Inflammasomes; Interleukin-18; Male; NLR Fami

2021
Efficacy of N-Acetylserotonin and Melatonin in the EAE Model of Multiple Sclerosis.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2016, Volume: 11, Issue:4

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Femal

2016
Melatonin administration after pilocarpine-induced status epilepticus: a new way to prevent or attenuate postlesion epilepsy?
    Epilepsy & behavior : E&B, 2011, Volume: 20, Issue:4

    Topics: Analysis of Variance; Animals; Antioxidants; Cell Death; Disease Models, Animal; Hippocampus; Male;

2011
N-Acetylserotonin prevents the hypotension induced by bacterial lipopolysaccharides in the rat.
    European journal of pharmacology, 1993, Nov-30, Volume: 250, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Blood Pressure; Disease Models, Animal; Hypotension; Lipopolysa

1993