n-acetylneuraminic acid and Cancer of Pancreas

n-acetylneuraminic acid has been researched along with Cancer of Pancreas in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's3 (13.04)18.2507
2000's3 (13.04)29.6817
2010's13 (56.52)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Agrawal, P; Baptiste, G; Bar-Sagi, D; Chen, S; Hajdu, C; Kurz, E; Loomis, C; Mahal, LK; Vucic, E1
Cabral, H; Itoh, M; Khan, T; Matsumoto, A; Miyahara, Y; Miyazaki, T; Miyazawa, T; Suganami, T; Tachihara, Y1
Boelaars, K; Boon, L; de Haas, A; de Winde, CM; den Haan, JMM; Goossens-Kruijssen, L; Lindijer, D; Mebius, RE; Rodriguez, E; Springer, B; van der Haar Àvila, I; van Kooyk, Y; van Montfoort, N; van Vliet, SJ; Wang, D; Wehry, L; Wuhrer, M1
Ichihara, H; Matsumoto, Y; Motomura, M1
Barnett, D; Brand, RE; Drake, RR; Gao, C; Haab, BB; He, Z; Hsueh, P; Huang, Y; Hurd, MW; Liu, Y; Maitra, A; Partyka, K; Singhi, AD; Staal, B1
Arteta, B; Cobler, L; de Bolós, C; de Llorens, R; Ferri, MJ; Figueras, J; Llop, E; Ortiz, R; Pagès, L; Peracaula, R; Pérez-Garay, M; Vidal-Vanaclocha, F1
Chrostek, L; Cylwik, B; Gruszewska, E; Kedra, B; Kuklinski, A; Szmitkowski, M; Tobolczyk, J1
Ankeny, JS; Girgis, MD; Rochefort, MM; Tomlinson, JS1
Haglund, C; Joenväärä, S; Kontro, H; Renkonen, R1
Akasov, R; Burov, SV; Haq, S; Haxho, F; Markvicheva, E; Neufeld, RJ; Samuel, V; Szewczuk, MR1
Barrabés, S; De Llorens, R; Fort, E; Peracaula, R; Rudd, PM; Sarrats, A1
Aich, U; Almaraz, RT; Bhattacharya, R; Khanna, HS; Shah, S; Tan, E; Yarema, KJ1
Balzer, EM; Chen, SH; Dallas, MR; Konstantopoulos, K1
Chen, SH; Dallas, MR; Konstantopoulos, K; Maitra, A; Sharma, S; Streppel, MM1
Ishikawa, O; Korekane, H; Miyamoto, Y; Ohigashi, H; Takahashi, H; Yabu, M1
Amano, M; André, S; Detjen, KM; Eriksson, H; Gabius, HJ; Lehtiö, J; Manning, JC; Nishimura, S1
Anderson, MA; Heidt, D; Lubman, DM; Simeone, DM; Zhao, J1
Campbell, RB; Kalra, AV1
Duszyk, M; Thethi, K1
Beum, PV; Burdick, M; Cheng, PW; Hollingsworth, MA; Singh, J1
Paty, PB; Picon, AI; Schwarz, MA; Schwarz, RE; Wojciechowicz, DC1
Beatty, P; Ciborowski, P; Finn, OJ; Hanisch, FG; Stolz, DB1
Kamino, K; Kato, Y; Satake, K; Sowa, M; Umeyama, K; Yamamoto, S1

Other Studies

23 other study(ies) available for n-acetylneuraminic acid and Cancer of Pancreas

ArticleYear
Integrated Systems Analysis of the Murine and Human Pancreatic Cancer Glycomes Reveals a Tumor-Promoting Role for ST6GAL1.
    Molecular & cellular proteomics : MCP, 2021, Volume: 20

    Topics: Animals; beta-D-Galactoside alpha 2-6-Sialyltransferase; Carcinoma, Pancreatic Ductal; Female; Gene Expression Regulation, Neoplastic; Glycoproteins; Glycosylation; Humans; Male; Mice, Inbred C57BL; N-Acetylneuraminic Acid; Pancreas; Pancreatic Neoplasms; Polysaccharides; Proteome; Sialyltransferases; Systems Analysis

2021
Boronic Acid Ligands Can Target Multiple Subpopulations of Pancreatic Cancer Stem Cells via pH-Dependent Glycan-Terminal Sialic Acid Recognition.
    ACS applied bio materials, 2021, 09-20, Volume: 4, Issue:9

    Topics: Boronic Acids; Humans; Hydrogen-Ion Concentration; Ligands; N-Acetylneuraminic Acid; Neoplastic Stem Cells; Pancreatic Neoplasms; Polysaccharides; Tumor Microenvironment

2021
Unraveling the impact of sialic acids on the immune landscape and immunotherapy efficacy in pancreatic cancer.
    Journal for immunotherapy of cancer, 2023, Volume: 11, Issue:11

    Topics: Animals; Carcinoma, Pancreatic Ductal; CD8-Positive T-Lymphocytes; Humans; Immunotherapy; Mice; N-Acetylneuraminic Acid; Pancreatic Neoplasms; Sialic Acids; Tumor Microenvironment

2023
Nano-chemotherapy using cationic liposome that strategically targets the cell membrane potential of pancreatic cancer cells with negative charge.
    Bioorganic & medicinal chemistry letters, 2018, 04-15, Volume: 28, Issue:7

    Topics: Animals; Antineoplastic Agents; Cations; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Glycosphingolipids; Humans; Liposomes; Mice; Mice, Inbred BALB C; Molecular Structure; N-Acetylneuraminic Acid; Nanoparticles; Neoplasms, Experimental; Pancreatic Neoplasms; Phosphatidylserines; Structure-Activity Relationship

2018
The sTRA Plasma Biomarker: Blinded Validation of Improved Accuracy Over CA19-9 in Pancreatic Cancer Diagnosis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 05-01, Volume: 25, Issue:9

    Topics: Aged; Animals; Antigens, Tumor-Associated, Carbohydrate; Biomarkers, Tumor; CA-19-9 Antigen; Carcinoma, Pancreatic Ductal; Case-Control Studies; Female; Follow-Up Studies; Humans; Male; Mice; Middle Aged; N-Acetylneuraminic Acid; Pancreatic Neoplasms; Prognosis; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
α2,3-Sialyltransferase ST3Gal IV promotes migration and metastasis in pancreatic adenocarcinoma cells and tends to be highly expressed in pancreatic adenocarcinoma tissues.
    The international journal of biochemistry & cell biology, 2013, Volume: 45, Issue:8

    Topics: Adenocarcinoma; Aged; Animals; beta-Galactoside alpha-2,3-Sialyltransferase; Cell Membrane; Cell Movement; E-Selectin; Female; Flow Cytometry; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Male; Mice; Mice, Nude; Middle Aged; N-Acetylneuraminic Acid; Neoplasm Metastasis; Oligosaccharides; Pancreatic Neoplasms; Protein Binding; RNA, Messenger; Sialyl Lewis X Antigen; Sialyltransferases

2013
Serum sialic acid as a marker of pancreatic cancers.
    Clinical laboratory, 2013, Volume: 59, Issue:7-8

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Case-Control Studies; Female; Humans; Male; Middle Aged; N-Acetylneuraminic Acid; Neoplasm Metastasis; Pancreatic Neoplasms

2013
Metabolic exploitation of the sialic acid biosynthetic pathway to generate site-specifically labeled antibodies.
    Glycobiology, 2014, Volume: 24, Issue:1

    Topics: Animals; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Antibody Specificity; Cell Line, Tumor; Female; Humans; Hybridomas; Mice; Mice, Nude; N-Acetylneuraminic Acid; Pancreatic Neoplasms

2014
Comparison of sialylated N-glycopeptide levels in serum of pancreatic cancer patients, acute pancreatitis patients, and healthy controls.
    Proteomics, 2014, Volume: 14, Issue:15

    Topics: Case-Control Studies; Glycopeptides; Humans; N-Acetylneuraminic Acid; Pancreatic Neoplasms; Pancreatitis

2014
Sialylation transmogrifies human breast and pancreatic cancer cells into 3D multicellular tumor spheroids using cyclic RGD-peptide induced self-assembly.
    Oncotarget, 2016, Oct-04, Volume: 7, Issue:40

    Topics: Animals; Breast Neoplasms; Cell Adhesion; Cell Movement; Cell Proliferation; Female; Glycoproteins; Humans; Mice; N-Acetylneuraminic Acid; Pancreatic Neoplasms; Peptides, Cyclic; Spheroids, Cellular; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
Effect of sialic acid content on glycoprotein pI analyzed by two-dimensional electrophoresis.
    Electrophoresis, 2010, Volume: 31, Issue:17

    Topics: Adenocarcinoma; Algorithms; alpha 1-Antitrypsin; Electrophoresis, Gel, Two-Dimensional; Glycoproteins; Glycosylation; Haptoglobins; Humans; Isoelectric Point; Linear Models; Models, Chemical; N-Acetylneuraminic Acid; Pancreatic Neoplasms; Pancreatitis, Chronic; Ribonuclease, Pancreatic

2010
Metabolic oligosaccharide engineering with N-Acyl functionalized ManNAc analogs: cytotoxicity, metabolic flux, and glycan-display considerations.
    Biotechnology and bioengineering, 2012, Volume: 109, Issue:4

    Topics: Acylation; Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Azides; Breast Neoplasms; Butyric Acid; Cell Cycle; Cell Line, Tumor; CHO Cells; Click Chemistry; Cricetinae; Cricetulus; Drug Design; Glycocalyx; Glycoconjugates; Hexosamines; Humans; Jurkat Cells; Ketones; Molecular Structure; N-Acetylneuraminic Acid; Pancreatic Neoplasms; Structure-Activity Relationship

2012
Mucin 16 is a functional selectin ligand on pancreatic cancer cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:3

    Topics: Animals; Binding Sites; Blotting, Western; CA-125 Antigen; Cell Line; Cell Line, Tumor; CHO Cells; Chromatography, Affinity; Cricetinae; Cricetulus; E-Selectin; Flow Cytometry; Fucose; Humans; Immunoprecipitation; L-Selectin; Ligands; Membrane Proteins; N-Acetylneuraminic Acid; Neoplasm Metastasis; P-Selectin; Pancreatic Neoplasms; Polysaccharides; Protein Binding; RNA Interference; Tandem Mass Spectrometry

2012
Sialofucosylated podocalyxin is a functional E- and L-selectin ligand expressed by metastatic pancreatic cancer cells.
    American journal of physiology. Cell physiology, 2012, Sep-15, Volume: 303, Issue:6

    Topics: Animals; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; E-Selectin; Fucose; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; L-Selectin; Ligands; N-Acetylneuraminic Acid; Pancreatic Neoplasms; Sialoglycoproteins

2012
Accumulation of free Neu5Ac-containing complex-type N-glycans in human pancreatic cancers.
    Glycoconjugate journal, 2013, Volume: 30, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Carbohydrate Sequence; Female; Glucans; Glycomics; Humans; Male; Molecular Sequence Data; N-Acetylneuraminic Acid; Pancreatic Neoplasms

2013
Tumour suppressor p16(INK4a) - anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model.
    The FEBS journal, 2012, Volume: 279, Issue:21

    Topics: Anoikis; Carbohydrate Epimerases; Cell Membrane; Cyclin-Dependent Kinase Inhibitor p16; Galectin 1; Gene Expression Regulation, Enzymologic; Genes, Tumor Suppressor; Glycosylation; Humans; Lectins; N-Acetylneuraminic Acid; Pancreatic Neoplasms; Phosphotransferases (Alcohol Group Acceptor); Polysaccharides; Proteome; Spectrometry, Mass, Electrospray Ionization

2012
Comparative serum glycoproteomics using lectin selected sialic acid glycoproteins with mass spectrometric analysis: application to pancreatic cancer serum.
    Journal of proteome research, 2006, Volume: 5, Issue:7

    Topics: Case-Control Studies; Glycoproteins; Humans; Lectins; Mass Spectrometry; N-Acetylneuraminic Acid; Pancreatic Neoplasms; Proteome; Proteomics

2006
Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: overcoming cellular barriers for therapeutic gain.
    British journal of cancer, 2007, Oct-08, Volume: 97, Issue:7

    Topics: Acetylgalactosamine; Antimetabolites, Antineoplastic; Benzyl Compounds; Cell Proliferation; Fluorescent Antibody Technique; Fluorouracil; Glioblastoma; Glycosylation; Humans; Microscopy, Fluorescence; Mucin-1; N-Acetylneuraminic Acid; Neuraminidase; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured

2007
Decreased cell surface charge in cystic fibrosis epithelia.
    Cell biochemistry and function, 1997, Volume: 15, Issue:1

    Topics: Cell Membrane; Cell Size; Cystic Fibrosis; Electric Conductivity; Epithelial Cells; Humans; Membrane Potentials; N-Acetylneuraminic Acid; Neuraminidase; Pancreatic Neoplasms; Tumor Cells, Cultured

1997
Expression of core 2 beta-1,6-N-acetylglucosaminyltransferase in a human pancreatic cancer cell line results in altered expression of MUC1 tumor-associated epitopes.
    The Journal of biological chemistry, 1999, Aug-27, Volume: 274, Issue:35

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Carbohydrate Sequence; Cattle; Epitopes; Gene Expression Regulation, Neoplastic; Glycosylation; Humans; Molecular Sequence Data; Mucin-1; Mucins; N-Acetylglucosaminyltransferases; N-Acetylneuraminic Acid; Oligosaccharides; Pancreatic Neoplasms; Peptides; Polysaccharides; Sialyl Lewis X Antigen; Transfection; Tumor Cells, Cultured

1999
Wheatgerm agglutinin-mediated toxicity in pancreatic cancer cells.
    British journal of cancer, 1999, Volume: 80, Issue:11

    Topics: Antineoplastic Agents; Cell Division; Cell Membrane; Cell Survival; Chromatin; Humans; Kinetics; N-Acetylneuraminic Acid; Neuraminidase; Pancreatic Neoplasms; Phytohemagglutinins; Tumor Cells, Cultured; Wheat Germ Agglutinins

1999
Biochemical characterization of the soluble form of tumor antigen MUC1 isolated from sera and ascites fluid of breast and pancreatic cancer patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:3 Suppl

    Topics: Ascites; Breast Neoplasms; Carbohydrates; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Endosomes; Glycosylation; Humans; Immunoblotting; Microscopy, Electron; Models, Genetic; Monosaccharides; Mucin-1; N-Acetylneuraminic Acid; Neuraminidase; Pancreatic Neoplasms; Peptide Fragments; Protein Structure, Tertiary; Trypsin

2001
A comparative study of experimental and human pancreatic carcinoma with special reference to histochemical findings.
    The Japanese journal of surgery, 1987, Volume: 17, Issue:6

    Topics: Adenocarcinoma; Animals; Cricetinae; Glycosaminoglycans; Humans; N-Acetylneuraminic Acid; Pancreatic Neoplasms; Rats; Sialic Acids; Staining and Labeling

1987