Compounds > n-acetylneuraminic acid

n-acetylneuraminic acid and Atherosclerosis

n-acetylneuraminic acid has been researched along with Atherosclerosis in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (29.17)29.6817
2010's13 (54.17)24.3611
2020's4 (16.67)2.80

Authors

AuthorsStudies
Coker, JK; Dhar, C; Gordts, PLSM; Grunddal, KV; Hsiao, J; Kawanishi, K; Varki, A; Varki, N; Zengler, K1
Cao, M; Chen, D; Chen, Q; Gao, X; Guo, C; Guo, H; Li, J; Mi, S; Su, Y; Zhang, Y; Zhao, W; Zhou, X1
Chen, J; Liu, Y; Xu, D; Zhang, C1
Barnes, J; Lee, T; Litovsky, SH; Orr, AW; Patel, RP; Peretik, JM; Regal-McDonald, K; Somarathna, M; Traylor, JG1
Chen, X; Choudhury, B; Diaz, S; Freeze, HH; Kawanishi, K; Kitajima, K; Münster-Kühnel, A; Saha, S; Sasmal, A; Sato, C; Schoenhofen, IC; Sharma, K; Siddiqui, SS; Vaill, M; Varki, A1
Chen, L; Deng, X; Liu, Y; Yang, X; Yu, C; Zhang, J1
Bertrand, KA; Chen, X; Diaz, SL; Eliassen, H; Gregg, CJ; Khaw, KT; Khedri, Z; Luben, R; Nguyen, D; Padler-Karavani, V; Samraj, AN; Sawyer, S; Varki, A; Willett, W; Wu, K; Yu, H1
Bennasroune, A; Blaise, S; Bocquet, O; Duca, L; Heinz, A; Ihling, C; Kawecki, C; Linton, KJ; Martiny, L; Maurice, P; Romier, B; Schmelzer, CEH; Terryn, C; Wahart, A1
Glanz, VY; Grechko, AV; Myasoedova, VA; Orekhov, AN1
Döring, Y; Drechsler, M; Hartwig, H; Kramp, B; Langer, M; Lievens, D; Mandl, M; Marth, JD; Megens, RT; Neideck, C; Noels, H; Soehnlein, O; Sperandio, M; Theelen, W; Tilstam, PV; Weber, C1
Ashline, D; Layne, MD; Liu, L; Ravid, K; Reinhold, V; Robbins, PW; Shaw, SY; Tassa, C; Xu, YX1
Bashir, M; Khan, RU1
Dong, R; Guo, S; Li, Y; Qin, S; Si, Y; Tian, H; Yang, N; Yao, S; Zhang, Y; Zhou, Y1
Alisson-Silva, F; Kawanishi, K; Varki, A1
Aktürk, M; Altay, M; Arslan, M; Ateş, İ; Bukan, N; Çakır, N; Cerit, ET; Karakoç, MA; Yılmaz Demirtaş, C1
Guan, T; Guo, S; Liu, Q; Qin, S; Tian, H; Yang, N; Yao, S; Zhang, Y; Zong, C1
Aksenov, DV; Gabbasov, ZA; Medvedeva, LA; Orekhov, AN; Popov, EV; Skalbe, TA; Sobenin, IA; Tertov, VV1
Akin, L; Kendirci, M; Kurtoglu, S; Mazicioglu, M; Muhtaroğlu, S; Yikilmaz, A1
Aksenov, DV; Ivanova, OA; Kaplun, VV; Mel'nichenko, AA; Orekhov, AN; Panasenko, OM; Popov, EV; Sobenin, IA; Suprun, IV; Tertov, VV1
Aznar, J; Ferrando, F; Martínez-Sales, V; Mira, Y; Reganon, E; Vayá, A; Vila, V1
Dallar, Y; Savas Erdeve, S; Topkaya, BC; Yilmaz, FM; Yilmaz, G; Yücel, D1
Lindberg, G1
Espinosa, B; Fortoul, T; Guevara, J; Masso, F; Montaño, LF; Paez, A; Rendon, E; Rodriguez, E; Varela, E1
Grapsa, E; Papamichael, C; Rammos, G; Samouilidou, E; Stamatelopoulos, K; Tseke, P; Zakopoulos, N1

Reviews

3 review(s) available for n-acetylneuraminic acid and Atherosclerosis

ArticleYear
Sialic acid metabolism as a potential therapeutic target of atherosclerosis.
    Lipids in health and disease, 2019, Sep-14, Volume: 18, Issue:1

    Topics: Animals; Atherosclerosis; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Glycoproteins; Humans; LDL-Receptor Related Proteins; Lipoproteins, LDL; MAP Kinase Kinase 4; Molecular Targeted Therapy; N-Acetylneuraminic Acid; Neuraminidase; rho-Associated Kinases; Sialic Acid Binding Immunoglobulin-like Lectins; Sialyltransferases; Signal Transduction

2019
Trans-sialidase Associated with Atherosclerosis: Defining the Identity of a Key Enzyme Involved in the Pathology.
    Current drug targets, 2019, Volume: 20, Issue:9

    Topics: Animals; Atherosclerosis; Calcium; Humans; Hydrogen-Ion Concentration; Lipoproteins, LDL; N-Acetylneuraminic Acid; Sialyltransferases; Substrate Specificity

2019
Human risk of diseases associated with red meat intake: Analysis of current theories and proposed role for metabolic incorporation of a non-human sialic acid.
    Molecular aspects of medicine, 2016, Volume: 51

    Topics: Animals; Atherosclerosis; Cattle; Colorectal Neoplasms; Diet; Humans; Models, Biological; N-Acetylneuraminic Acid; Red Meat; Risk Factors

2016

Trials

1 trial(s) available for n-acetylneuraminic acid and Atherosclerosis

ArticleYear
Lower hypoglycemic but higher antiatherogenic effects of bitter melon than glibenclamide in type 2 diabetic patients.
    Nutrition journal, 2015, Jan-26, Volume: 14

    Topics: Adult; Aged; Atherosclerosis; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Endpoint Determination; Fasting; Female; Glucose Tolerance Test; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Momordica charantia; N-Acetylneuraminic Acid; Phytotherapy

2015

Other Studies

20 other study(ies) available for n-acetylneuraminic acid and Atherosclerosis

ArticleYear
Dietary Neu5Ac Intervention Protects Against Atherosclerosis Associated With Human-Like Neu5Gc Loss-Brief Report.
    Arteriosclerosis, thrombosis, and vascular biology, 2021, Volume: 41, Issue:11

    Topics: Animal Feed; Animals; Antibodies; Aorta; Aortic Diseases; Atherosclerosis; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Foam Cells; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Mixed Function Oxygenases; N-Acetylneuraminic Acid; Neuraminic Acids; Pan troglodytes; Plaque, Atherosclerotic; Receptors, LDL; Sialadenitis; THP-1 Cells

2021
N-acetylneuraminic acid and chondroitin sulfate modified nanomicelles with ROS-sensitive H
    International journal of biological macromolecules, 2022, Jun-30, Volume: 211

    Topics: Atherosclerosis; Chondroitin Sulfates; E-Selectin; Endothelial Cells; Humans; Hyaluronan Receptors; N-Acetylneuraminic Acid; Reactive Oxygen Species

2022
Assessment of ICAM-1 N-glycoforms in mouse and human models of endothelial dysfunction.
    PloS one, 2020, Volume: 15, Issue:3

    Topics: Adult; Aged; Animals; Arteries; Arteriovenous Shunt, Surgical; Atherosclerosis; Disease Models, Animal; Endothelium, Vascular; Epitopes; Female; Glycosylation; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; Macrophages; Male; Mannose; Mice; Mice, Knockout, ApoE; Middle Aged; N-Acetylneuraminic Acid; Protein Isoforms; Young Adult

2020
Evolutionary conservation of human ketodeoxynonulosonic acid production is independent of sialoglycan biosynthesis.
    The Journal of clinical investigation, 2021, 03-01, Volume: 131, Issue:5

    Topics: Atherosclerosis; HEK293 Cells; Human Umbilical Vein Endothelial Cells; Humans; Kidney Failure, Chronic; N-Acetylneuraminic Acid; Polysaccharides

2021
ST6GAL1 negatively regulates monocyte transendothelial migration and atherosclerosis development.
    Biochemical and biophysical research communications, 2018, 06-02, Volume: 500, Issue:2

    Topics: Animals; Antigens, CD; Atherosclerosis; beta Catenin; Down-Regulation; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Male; Mice, Inbred C57BL; Monocytes; N-Acetylneuraminic Acid; Plaque, Atherosclerotic; Sialyltransferases; Transendothelial and Transepithelial Migration; Tumor Necrosis Factor-alpha

2018
Polyclonal human antibodies against glycans bearing red meat-derived non-human sialic acid N-glycolylneuraminic acid are stable, reproducible, complex and vary between individuals: Total antibody levels are associated with colorectal cancer risk.
    PloS one, 2018, Volume: 13, Issue:6

    Topics: Adult; Aged; Antibodies; Atherosclerosis; Autoantigens; Colorectal Neoplasms; Diabetes Mellitus, Type 2; Epitopes; Female; Humans; Middle Aged; N-Acetylneuraminic Acid; Neuraminic Acids; Polysaccharides; Red Meat; Risk Factors

2018
Identification of CD36 as a new interaction partner of membrane NEU1: potential implication in the pro-atherogenic effects of the elastin receptor complex.
    Cellular and molecular life sciences : CMLS, 2019, Volume: 76, Issue:4

    Topics: Animals; Atherosclerosis; CD36 Antigens; Cell Membrane; Chlorocebus aethiops; COS Cells; Elastin; Humans; Lipoproteins, LDL; Macrophages; N-Acetylneuraminic Acid; Neuraminidase; Peptides; Protein Binding; Proteomics; Receptors, Cell Surface; RNA Interference; THP-1 Cells

2019
Deficiency of the sialyltransferase St3Gal4 reduces Ccl5-mediated myeloid cell recruitment and arrest: short communication.
    Circulation research, 2014, Mar-14, Volume: 114, Issue:6

    Topics: Animals; Apolipoproteins E; Atherosclerosis; beta-Galactoside alpha-2,3-Sialyltransferase; Chemokine CCL2; Chemokine CCL5; Dietary Fats; Female; Inflammation; Intercellular Adhesion Molecule-1; Leukocyte Rolling; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cells; N-Acetylneuraminic Acid; Neuraminidase; Protein Processing, Post-Translational; Sialyltransferases; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2014
The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis.
    Journal of lipid research, 2015, Volume: 56, Issue:2

    Topics: Animals; Atherosclerosis; Cell Line; Chlorocebus aethiops; COS Cells; Glycosylation; HeLa Cells; Heparan Sulfate Proteoglycans; Humans; Immunohistochemistry; Lipoproteins, LDL; Microscopy, Confocal; Mutagenesis, Site-Directed; N-Acetylneuraminic Acid; Rats; Receptors, LDL

2015
Exogenous supplement of N-acetylneuraminic acid ameliorates atherosclerosis in apolipoprotein E-deficient mice.
    Atherosclerosis, 2016, Volume: 251

    Topics: Animals; Antioxidants; Aorta; Atherosclerosis; Biological Assay; Cholesterol; Inflammation; Intercellular Adhesion Molecule-1; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; N-Acetylneuraminic Acid; Oxidative Stress; Oxygen; Quercetin; Triglycerides; Tumor Necrosis Factor-alpha

2016
Serum Total Sialic Acid Level is Elevated in Hypothyroid Patients as an Atherosclerotic Risk Factor.
    Journal of clinical laboratory analysis, 2017, Volume: 31, Issue:2

    Topics: Adolescent; Adult; Atherosclerosis; Autoantibodies; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Carotid Intima-Media Thickness; Cross-Sectional Studies; Female; Humans; Hypothyroidism; Lipoproteins, LDL; Male; Middle Aged; N-Acetylneuraminic Acid; Risk Factors; Thyroid Hormones; Uric Acid; Young Adult

2017
Synthesis and cardiovascular protective effects of quercetin 7-O-sialic acid.
    Journal of cellular and molecular medicine, 2017, Volume: 21, Issue:1

    Topics: Animals; Apolipoprotein A-I; Atherosclerosis; ATP-Binding Cassette Transporters; Cardiotonic Agents; Cell Line; Chemokine CCL2; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Macrophages; Mice; N-Acetylneuraminic Acid; Oxidative Stress; Quercetin; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2017
Deglycosylation of apo B-containing lipoproteins increase their ability to aggregate and to promote intracellular cholesterol accumulation in vitro.
    Archives of physiology and biochemistry, 2008, Volume: 114, Issue:5

    Topics: Adult; Apolipoprotein B-100; Atherosclerosis; Cholesterol; Glycoside Hydrolases; Glycosylation; Humans; Intracellular Space; Lipoproteins; Lipoproteins, VLDL; Male; Mannose; Middle Aged; N-Acetylneuraminic Acid; Protein Binding

2008
The association of serum sialic acid with carotid intima-media thickness and anthropometric and metabolic parameters in obese children and adolescents.
    Annals of nutrition & metabolism, 2011, Volume: 59, Issue:2-4

    Topics: Adipose Tissue; Adolescent; Anthropometry; Atherosclerosis; Biomarkers; Blood Glucose; Carotid Intima-Media Thickness; Child; Cross-Sectional Studies; Female; Humans; Insulin; Insulin Resistance; Lipids; Male; Metabolic Syndrome; N-Acetylneuraminic Acid; Obesity; Risk Factors

2011
Desialylation decreases the resistance of apo B-containing lipoproteins to aggregation and increases their atherogenic potential.
    Bulletin of experimental biology and medicine, 2005, Volume: 140, Issue:1

    Topics: Analysis of Variance; Apolipoproteins B; Atherosclerosis; Humans; Lipoproteins; Lipoproteins, IDL; Lipoproteins, VLDL; Muscle, Smooth, Vascular; N-Acetylneuraminic Acid; Neuraminidase; Newcastle disease virus

2005
Sialic acid is an inflammation marker associated with a history of deep vein thrombosis.
    Thrombosis research, 2007, Volume: 119, Issue:1

    Topics: Adolescent; Adult; Aged; Atherosclerosis; Blood Coagulation; C-Reactive Protein; Female; Fibrin Fibrinogen Degradation Products; Humans; Inflammation; Lipids; Male; Middle Aged; N-Acetylneuraminic Acid; Prothrombin; Venous Thrombosis

2007
Serum sialic acid, hs-CRP and oxidative stress parameters in obese children.
    Journal of pediatric endocrinology & metabolism : JPEM, 2007, Volume: 20, Issue:2

    Topics: Atherosclerosis; Biomarkers; Blood Glucose; Body Mass Index; C-Reactive Protein; Case-Control Studies; Child; Cholesterol; Female; Humans; Male; Malondialdehyde; N-Acetylneuraminic Acid; Obesity; Oxidative Stress; Risk Factors; Sulfhydryl Compounds

2007
Resialylation of sialic acid deficit vascular endothelium, circulating cells and macromolecules may counteract the development of atherosclerosis: a hypothesis.
    Atherosclerosis, 2007, Volume: 192, Issue:2

    Topics: Atherosclerosis; Blood Platelets; Endothelium, Vascular; Glycolipids; Glycoproteins; Humans; Macrophages; Models, Cardiovascular; N-Acetylneuraminic Acid

2007
Altered detection of molecules associated with leukocyte traffic in HUVECs derived from newborns with a strong family history of myocardial infarction.
    Acta histochemica, 2008, Volume: 110, Issue:1

    Topics: Adult; Atherosclerosis; Blotting, Western; Cell Movement; Cell Proliferation; Cells, Cultured; Claudin-5; Endothelial Cells; Female; Humans; Immunohistochemistry; Infant, Newborn; Jurkat Cells; Lectins; Leukocytes; Membrane Proteins; Microscopy, Fluorescence; Myocardial Infarction; N-Acetylneuraminic Acid; Pregnancy; Umbilical Veins

2008
Correlations of sialic acid with markers of inflammation, atherosclerosis and cardiovascular events in hemodialysis patients.
    Blood purification, 2008, Volume: 26, Issue:3

    Topics: Aged; Atherosclerosis; Disease Susceptibility; Female; Follow-Up Studies; Humans; Inflammation; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Ischemia; N-Acetylneuraminic Acid; Prospective Studies; Renal Dialysis; Stroke; Survival Analysis

2008