n-acetylneuraminic acid has been researched along with Alzheimer Disease in 26 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (11.54) | 18.2507 |
2000's | 8 (30.77) | 29.6817 |
2010's | 8 (30.77) | 24.3611 |
2020's | 7 (26.92) | 2.80 |
Authors | Studies |
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Wu, J; Wu, M; Wu, N; Zhan, X; Zhang, H | 1 |
Haroutunian, V; Moon, HJ; Zhao, L | 1 |
Angiolillo, A; Aniello, F; Di Costanzo, A; Donizetti, A; Febbraio, F; Rendina, A; Tortora, F; Vitale, E | 1 |
Adam, M; Brandis, A; Cahalon, L; Clark, AR; Colaiuta, SP; Croese, T; Gold, O; Greka, A; Habib, N; Itkin, M; Kitsberg, D; Kohnert, E; Malitsky, S; Medina, S; Mehlman, T; Ravid, A; Salame, TM; Schwartz, M; Shapira, I; Slyper, M; Suzzi, S; Vernon, KA | 1 |
Gaunitz, S; Schedin-Weiss, S; Tjernberg, LO | 1 |
Ahmad, K; Garg, RK; Mahdi, AA; Srivastava, S; Verma, AK; Yadav, J | 1 |
Chen, X; Li, W; Yang, K; Yang, Z | 1 |
Huang, X; Kouyoumdjian, H; Mallett, C; Nasr, SH; Ramadan, S; Shapiro, EM; Zhu, DC | 1 |
Suzuki, A; Tsuda, L; Yamasaki, Y; Yanagisawa, K | 1 |
Dang, Y; Geng, P; Geng, R; Hu, X; Lei, L; Li, L; Tian, Y; Xu, Z; Zhang, W | 1 |
Crisostomo, AC; Finke, JM; Kwon, H; Smalls, HM | 1 |
Kikkeri, R; Murthy, RV; Yadav, R | 1 |
Liu, J; Liu, Y; Sun, J; Yang, L; Yin, T; Zhou, X | 1 |
García Rodríguez, JC; Maurice, T; Rodríguez Cruz, Y; Rodríguez Obaya, T; Strehaiano, M | 1 |
Banks, WA; Finke, JM | 1 |
Cowan, CB; Good, TA; Patel, DA | 1 |
Yamauchi, K | 1 |
Baboolal, N; Davis, G; McRae, A; Nayak, S | 1 |
Berman, P; de Villiers, N; Hon, D; MacGregor, P; Potocnik, F; van Rensburg, SJ | 1 |
Ito, A; Kakuyama, H; Möller, A; Näslund, J; Söderberg, L; Tjernberg, LO; Winblad, B | 1 |
Miyatake, T; Saito, F; Saito, K; Sodeyama, N; Yanagisawa, K | 1 |
Alafuzoff, I; Miettinen, R; Mikkonen, M; Soininen, H; Tapiola, T | 1 |
Ariga, T; Hasegawa, A; Ishida, H; Kiso, M; Kobayashi, K; Miyatake, T | 1 |
Berman, PA; Potocnik, FC; Taljaard, JJ; van Rensburg, SJ | 1 |
Gong, CX; Grundke-Iqbal, I; Iqbal, K; Liu, F; Merkle, RK; Zaidi, T | 1 |
Cosović, C; Drnovsek, V; Heffer-Lauc, M; Kracun, I; Lauc, G; Rosner, H | 1 |
3 review(s) available for n-acetylneuraminic acid and Alzheimer Disease
Article | Year |
---|---|
The significance of sialylation on the pathogenesis of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Brain; Glycosylation; Humans; N-Acetylneuraminic Acid | 2021 |
Modulators of IgG penetration through the blood-brain barrier: Implications for Alzheimer's disease immunotherapy.
Topics: Alzheimer Disease; Animals; Antibodies, Bispecific; Antibodies, Monoclonal; Biological Transport; Blood-Brain Barrier; Brain; Carbohydrate Conformation; Gene Expression Regulation; Glycosylation; Histocompatibility Antigens Class I; Humans; Immunoglobulin G; Immunotherapy; N-Acetylneuraminic Acid; Protein Engineering; Receptors, Fc | 2017 |
[Characterization of sialo-apolipoprotein E in human cerebrospinal fluid].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Biological Transport; Brain; Cholesterol; Humans; Lipid Metabolism; Lipoproteins; N-Acetylneuraminic Acid; Particle Size; Protein Binding | 2009 |
1 trial(s) available for n-acetylneuraminic acid and Alzheimer Disease
Article | Year |
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Anti-aβ oligomer IgG and surface sialic acid in intravenous immunoglobulin: measurement and correlation with clinical outcomes in Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Biopolymers; Humans; Immunoglobulin G; Immunoglobulins, Intravenous; N-Acetylneuraminic Acid; Surface Plasmon Resonance; Treatment Outcome | 2015 |
22 other study(ies) available for n-acetylneuraminic acid and Alzheimer Disease
Article | Year |
---|---|
An Oligomannuronic Acid-Sialic Acid Conjugate Capable of Inhibiting Aβ42 Aggregation and Alleviating the Inflammatory Response of BV-2 Microglia.
Topics: Alginic Acid; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Cell Line, Transformed; Cell Proliferation; Cell Survival; Cytokines; Mice; Microglia; N-Acetylneuraminic Acid; Peptide Fragments; Protein Aggregates; Protein Aggregation, Pathological; Signal Transduction | 2021 |
Human apolipoprotein E isoforms are differentially sialylated and the sialic acid moiety in ApoE2 attenuates ApoE2-Aβ interaction and Aβ fibrillation.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Apolipoproteins E; Brain; Humans; N-Acetylneuraminic Acid; Protein Isoforms | 2022 |
CD33 rs2455069 SNP: Correlation with Alzheimer's Disease and Hypothesis of Functional Role.
Topics: Alzheimer Disease; Genome-Wide Association Study; Humans; Microglia; N-Acetylneuraminic Acid; Polymorphism, Single Nucleotide; Sialic Acid Binding Ig-like Lectin 3 | 2022 |
N-acetylneuraminic acid links immune exhaustion and accelerated memory deficit in diet-induced obese Alzheimer's disease mouse model.
Topics: Alzheimer Disease; Animals; Diet, High-Fat; Disease Models, Animal; Humans; Memory Disorders; Mice; Mice, Transgenic; N-Acetylneuraminic Acid; Obesity | 2023 |
The N-glycan profile in cortex and hippocampus is altered in Alzheimer disease.
Topics: Acetylglucosamine; Aged; Aged, 80 and over; Alzheimer Disease; Asparagine; Brain Chemistry; Cerebral Cortex; Chromatography, Gel; Chromatography, High Pressure Liquid; Epitopes; Female; Fucose; Galactose; Glycoproteins; Hippocampus; Humans; Male; N-Acetylneuraminic Acid; Polysaccharides; Tandem Mass Spectrometry | 2021 |
Sialic acid associated with oxidative stress and total antioxidant capacity (TAC) expression level as a predictive indicator in moderate to severe Alzheimer's disease.
Topics: Alzheimer Disease; Antioxidants; Catalase; Female; Glutathione; Glutathione Peroxidase; Humans; Lipid Peroxidation; Male; N-Acetylneuraminic Acid; Oxidative Stress; Superoxide Dismutase | 2020 |
Detection of β-Amyloid by Sialic Acid Coated Bovine Serum Albumin Magnetic Nanoparticles in a Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Brain; Contrast Media; Disease Models, Animal; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice; Mice, Transgenic; N-Acetylneuraminic Acid; Serum Albumin, Bovine | 2018 |
Induction of ganglioside synthesis in Drosophila brain accelerates assembly of amyloid β protein.
Topics: Acetyltransferases; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cell Membrane; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; G(M1) Ganglioside; Galactosyltransferases; Gangliosides; Humans; N-Acetylneuraminic Acid; Protein Binding; Transgenes | 2018 |
Glycopeptide Nanofiber Platform for Aβ-Sialic Acid Interaction Analysis and Highly Sensitive Detection of Aβ.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cattle; Glycopeptides; Humans; N-Acetylneuraminic Acid; Nanofibers; Peptide Fragments; Protein Aggregates; Protein Aggregation, Pathological; Spectrometry, Fluorescence | 2019 |
Sialic Acid Hydroxamate: A Potential Antioxidant and Inhibitor of Metal-Induced β-Amyloid Aggregates.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cell Line, Tumor; Cell Survival; Chelating Agents; Free Radical Scavengers; Humans; Hydroxamic Acids; N-Acetylneuraminic Acid; Neuroprotective Agents; Oxidative Stress; Protein Aggregates; Protein Aggregation, Pathological | 2015 |
Sialic acid (SA)-modified selenium nanoparticles coated with a high blood-brain barrier permeability peptide-B6 peptide for potential use in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Biological Transport; Blood-Brain Barrier; Coated Materials, Biocompatible; Cytoprotection; Membrane Potential, Mitochondrial; Mice; Microscopy, Confocal; N-Acetylneuraminic Acid; Nanoparticles; Oligopeptides; PC12 Cells; Peptides; Permeability; Protein Aggregates; Rats; Selenium | 2015 |
An Intranasal Formulation of Erythropoietin (Neuro-EPO) Prevents Memory Deficits and Amyloid Toxicity in the APPSwe Transgenic Mouse Model of Alzheimer's Disease.
Topics: Administration, Intranasal; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cerebral Cortex; Disease Models, Animal; Erythropoietin; Hippocampus; Maze Learning; Memory; Memory Disorders; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; N-Acetylneuraminic Acid; Neuroprotective Agents; Nootropic Agents | 2017 |
Exploring the mechanism of beta-amyloid toxicity attenuation by multivalent sialic acid polymers through the use of mathematical models.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomimetic Materials; Cell Membrane; Cell Survival; Cells, Cultured; Humans; Models, Biological; N-Acetylneuraminic Acid; Neurons; Protein Binding | 2009 |
Sialic acid, homocysteine and CRP: potential markers for dementia.
Topics: Aged; Alzheimer Disease; Biomarkers; C-Reactive Protein; Dementia; Female; Homocysteine; Humans; Male; N-Acetylneuraminic Acid; Reproducibility of Results; Sensitivity and Specificity | 2009 |
5- and 6-glycosylation of transferrin in patients with Alzheimer's disease.
Topics: Alcoholism; Alzheimer Disease; Free Radicals; Glycosylation; Heterozygote; Homozygote; Humans; Isoelectric Focusing; N-Acetylneuraminic Acid; Oxidation-Reduction; Transferrin | 2004 |
Characterization of the Alzheimer's disease-associated CLAC protein and identification of an amyloid beta-peptide-binding site.
Topics: Alzheimer Disease; Amino Acid Motifs; Amino Acid Sequence; Amyloid beta-Peptides; Binding Sites; Cell Line; Circular Dichroism; Glycosylation; Heparin; Humans; Mutagenesis; N-Acetylneuraminic Acid; Non-Fibrillar Collagens; Pepsin A; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Recombinant Proteins; Salts | 2005 |
Developmental changes of sialylation of soluble beta/A4 amyloid protein precursor derivatives in human cerebrospinal fluid.
Topics: Adult; Age Factors; Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Antibodies; Blotting, Western; Child; Humans; Infant; Molecular Weight; N-Acetylneuraminic Acid; Neuraminidase; Sialic Acids | 1994 |
Hippocampal plasticity in Alzheimer's disease: changes in highly polysialylated NCAM immunoreactivity in the hippocampal formation.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antibody Specificity; Blotting, Western; Dentate Gyrus; Entorhinal Cortex; Female; Humans; Male; Microscopy, Electron; N-Acetylneuraminic Acid; Neural Cell Adhesion Molecules; Neuronal Plasticity; Neurons | 1999 |
Characterization of high-affinity binding between gangliosides and amyloid beta-protein.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Gangliosides; Humans; N-Acetylneuraminic Acid; Structure-Activity Relationship; Surface Plasmon Resonance | 2001 |
Glycosylation of transferrin in Alzheimer's disease and alcohol-induced dementia.
Topics: Adult; Alcoholism; Alzheimer Disease; Glycosylation; Humans; Male; N-Acetylneuraminic Acid; Oligosaccharides; Transferrin | 2000 |
Role of glycosylation in hyperphosphorylation of tau in Alzheimer's disease.
Topics: Acetylglucosamine; Alzheimer Disease; Glycosylation; Hexoses; Humans; N-Acetylneuraminic Acid; Neurofibrillary Tangles; Nucleotidyltransferases; Phosphorylation; Protein Processing, Post-Translational; tau Proteins | 2002 |
Human brain gangliosides in development, aging and disease.
Topics: Adolescent; Adult; Aged; Aging; Alzheimer Disease; Brain; Brain Chemistry; Child; Child, Preschool; Gangliosides; Humans; Infant; Infant, Newborn; Middle Aged; N-Acetylneuraminic Acid; Sialic Acids | 1991 |