Page last updated: 2024-08-24

n-acetylaspartic acid and Stroke

n-acetylaspartic acid has been researched along with Stroke in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's23 (62.16)29.6817
2010's13 (35.14)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Attard, KJ; Boyd, LA; Ferris, JK; Greeley, B; Hayward, KS; MacKay, AL; Neva, JL; Vavasour, IM; Wadden, KP1
Chen, W; Gong, ZK; Sheng, C; Wang, M; Wang, SY; Wang, XX1
Choi, CG; Choi, Y; Ha, HK; Ham, SJ; Jeon, SB; Jung, SC; Kim, J; Kim, JK; Kim, KW; Kim, ST; Kwon, JI; Shim, WH; Sung, YS; Woo, CW; Woo, DC1
Chong, RA; DeGiorgio, CM; Galati, A; Hovsepian, DA; Mazumder, R; Mishra, S; Yim, C1
Dumez, JN; Frydman, L; Grant, SC; Rosenberg, JT; Shemesh, N1
Huber, VJ; Ida, M; Igarashi, H; Nakada, T; Suzuki, Y1
Blamire, AM; Ford, GA; Hallsworth, K; He, J; Jakovljevic, DG; Moore, SA; Rochester, L; Trenell, MI1
Meng, N; Shi, S; Su, Y1
Borich, MR; Boyd, LA; Jones, PW; Mackay, A; Vavsour, I1
Carlson, HL; Harris, AD; Kirton, A; MacMaster, FP1
de Graaf, RA; Dijkhuizen, RM; van der Zijden, JP; van Eijsden, P1
Baron, JC1
Rohr, A; Stephani, U; van Baalen, A1
Armitage, PA; Bastin, ME; Chappell, FM; Cvoro, V; Marshall, I; Muñoz Maniega, S; Wardlaw, JM1
Armitage, PA; Bastin, ME; Carpenter, TK; Cvoro, V; Dennis, MS; Farrall, AJ; Marshall, I; Rivers, CS; Wardlaw, JM; Wartolowska, K1
Ikawa, M; Kimura, H; Kudo, T; Kuriyama, M; Okazawa, H; Shimizu, Y; Toyooka, M; Tsujikawa, T; Uematsu, H; Yoneda, M1
An, L; Baker, EH; Latour, LL; Shen, J; Thomasson, DM; Warach, S; Zhang, Y1
Chen, W; Geng, D; Huang, Y; Li, Y; Shi, X; Wu, X1
Li, MH; Li, YH; Lu, J; Sun, XJ; Wang, X; Ye, JL; Zhang, B; Zhao, JG1
Brooks, WM; Choi, IY; Cirstea, CM; Craciunas, SC; Lee, P; Nudo, RJ; Popescu, EA; Savage, CR; Yeh, HW1
Beley, A; Bertrand, N; Demougeot, C; Garnier, P; Giroud, M; Marie, C; Mossiat, C; Prigent-Tessier, A1
Confort-Gouny, S; Cozzone, PJ; Denis, B; Lefur, Y; Nicoli, F; Ranjeva, JP1
Barantin, L; Montharu, J; Nadal-Desbarats, L; Pourcelot, L; Seguin, F; Serriere, S; Vial, F1
Ben Salem, D; Brunotte, F; Giroud, M; Lalande, A; Walker, PM1
Lanfermann, H; Neumann-Haefelin, C; Neumann-Haefelin, T; Pilatus, U; Singer, OC; Stengel, A; Zanella, FE1
Brodaty, H; Ross, AJ; Sachdev, PS; Valenzuela, MJ; Wen, W1
Glodzik-Sobanska, L; Kieltyka, A; Kozub, J; Slowik, A; Sobiecka, B; Szczudlik, A; Urbanik, A1
de Leon, MJ; Glodzik-Sobanska, L; Li, J; Mosconi, L; Slowik, A; Sobiecka, B; Szczudlik, A; Walecki, J1
Benner, T; Gonzalez, RG; Koroshetz, WJ; Lee, V; Ratai, E; Schaefer, PW; Singhal, AB; Sorensen, AG; Vangel, M1
Blamire, AM; Flitney, D; Matthews, PM; Pendlebury, ST; Pineiro, R; Smith, S; Styles, P1
Blamire, AM; Lee, MA; Matthews, PM; Pendlebury, ST; Styles, P1
Barber, PA; Darby, DG; Davis, SM; Desmond, PM; Gerraty, RP; Li, T; Parsons, MW; Tress, BM; Yang, Q1
Marshall, I; Wardlaw, JM; Warlow, CP; Wild, JM1
Krasnewich, D; Pearl, PL1
Kobayashi, M; Mihara, B; Suga, S; Takayama, H1
Chu, WJ; Hetherington, HP; Liu, HG; Mason, GF; Mountz, JM; Pan, JW; San Pedro, EC1
Beley, A; Brunotte, F; Demougeot, C; Giroud, M; Marie, C; Rouaud, O; Walker, P1

Reviews

1 review(s) available for n-acetylaspartic acid and Stroke

ArticleYear
N-acetylaspartate decrease in acute stage of ischemic stroke: a perspective from experimental and clinical studies.
    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2015, Volume: 14, Issue:1

    Topics: Acute Disease; Animals; Aspartic Acid; Brain; Brain Ischemia; Humans; Magnetic Resonance Spectroscopy; Rats; Stroke

2015

Trials

8 trial(s) available for n-acetylaspartic acid and Stroke

ArticleYear
Effects of Community Exercise Therapy on Metabolic, Brain, Physical, and Cognitive Function Following Stroke: A Randomized Controlled Pilot Trial.
    Neurorehabilitation and neural repair, 2015, Volume: 29, Issue:7

    Topics: Aged; Aspartic Acid; Body Composition; Brain; Cognition Disorders; Exercise Test; Exercise Therapy; Female; Humans; Lipid Metabolism; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Pilot Projects; Residence Characteristics; Single-Blind Method; Stroke; Stroke Rehabilitation; Treatment Outcome; Visual Analog Scale

2015
Metabolic counterpart of decreased apparent diffusion coefficient during hyperacute ischemic stroke: a brain proton magnetic resonance spectroscopic imaging study.
    Stroke, 2003, Volume: 34, Issue:7

    Topics: Acute Disease; Adult; Aged; Aspartic Acid; Brain; Brain Ischemia; Cerebrovascular Circulation; Diffusion; Diffusion Magnetic Resonance Imaging; Disease Progression; Female; Gadolinium; Humans; Lactic Acid; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Protons; Stroke; Time Factors

2003
1H MRS in stroke patients with and without cognitive impairment.
    Neurobiology of aging, 2005, Volume: 26, Issue:6

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Cerebral Cortex; Choline; Cognition Disorders; Cohort Studies; Comorbidity; Dementia, Vascular; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Tissue Proteins; Neurotransmitter Agents; Protons; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke; Tissue Distribution

2005
Magnetic resonance spectroscopy study of oxygen therapy in ischemic stroke.
    Stroke, 2007, Volume: 38, Issue:10

    Topics: Acute Disease; Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Ischemia; Diffusion Magnetic Resonance Imaging; Energy Metabolism; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Middle Aged; Oxygen Inhalation Therapy; Stroke

2007
Combined (1)H MR spectroscopy and diffusion-weighted MRI improves the prediction of stroke outcome.
    Neurology, 2000, Aug-22, Volume: 55, Issue:4

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Diffusion; Female; Humans; Infarction, Middle Cerebral Artery; Linear Models; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Prognosis; Prospective Studies; Stroke; Treatment Outcome

2000
Longitudinal changes of metabolites in frontal lobes after hemorrhagic stroke of basal ganglia: a proton magnetic resonance spectroscopy study.
    Stroke, 2001, Volume: 32, Issue:10

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Basal Ganglia Hemorrhage; Creatine; Disease Progression; Female; Frontal Lobe; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Severity of Illness Index; Stroke; Treatment Outcome

2001
Regional cerebral blood flow and magnetic resonance spectroscopic imaging findings in diaschisis from stroke.
    Stroke, 2002, Volume: 33, Issue:5

    Topics: Adult; Aged; Aspartic Acid; Blood Flow Velocity; Brain; Cerebral Infarction; Cerebrovascular Circulation; Creatine; Female; Humans; Internal Capsule; Magnetic Resonance Spectroscopy; Male; Middle Aged; Paresis; Predictive Value of Tests; Reference Values; Stroke; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon

2002
Spectroscopic data following stroke reveal tissue abnormality beyond the region of T2-weighted hyperintensity.
    Journal of the neurological sciences, 2002, Jul-15, Volume: 199, Issue:1-2

    Topics: Aspartic Acid; Choline; Creatine; Female; Humans; Infarction, Middle Cerebral Artery; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Severity of Illness Index; Stroke; Time Factors

2002

Other Studies

28 other study(ies) available for n-acetylaspartic acid and Stroke

ArticleYear
Cortical N-acetylaspartate concentrations are impacted in chronic stroke but do not relate to motor impairment: A magnetic resonance spectroscopy study.
    Human brain mapping, 2021, Volume: 42, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Chronic Disease; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Activity; Sensorimotor Cortex; Stroke; Upper Extremity

2021
Study on the clinical application of the MRS in the cognitive assessment after stroke.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:10

    Topics: Aspartic Acid; Cognition; Cognition Disorders; Cognitive Dysfunction; Creatine; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Stroke

2017
The administration of hydrogen sulphide prior to ischemic reperfusion has neuroprotective effects in an acute stroke model.
    PloS one, 2017, Volume: 12, Issue:11

    Topics: Animals; Apoptosis; Aspartic Acid; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Humans; Hydrogen Sulfide; Neuroprotective Agents; Rats; Reperfusion Injury; Stroke; Taurine

2017
MELAS: Monitoring treatment with magnetic resonance spectroscopy.
    Acta neurologica Scandinavica, 2019, Volume: 139, Issue:1

    Topics: Arginine; Aspartic Acid; Brain; Choline; Female; Humans; Magnetic Resonance Spectroscopy; MELAS Syndrome; Middle Aged; Stroke; Treatment Outcome

2019
Metabolic T1 dynamics and longitudinal relaxation enhancement in vivo at ultrahigh magnetic fields on ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:11

    Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebral Angiography; Cerebrovascular Circulation; Choline; Creatine; Female; Lactic Acid; Magnetic Resonance Angiography; Male; Rats; Rats, Sprague-Dawley; Stroke

2014
Proton magnetic resonance spectroscopy as a diagnostic biomarker in mild cognitive impairment following stroke in acute phase.
    Neuroreport, 2016, 05-25, Volume: 27, Issue:8

    Topics: Aged; Aspartic Acid; Biomarkers; Cognitive Dysfunction; Creatine; Female; Hippocampus; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Stroke

2016
Cortical thickness and metabolite concentration in chronic stroke and the relationship with motor function.
    Restorative neurology and neuroscience, 2016, 09-21, Volume: 34, Issue:5

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Cerebral Cortex; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Motor Activity; Proton Magnetic Resonance Spectroscopy; Stroke; Upper Extremity

2016
Spectroscopic biomarkers of motor cortex developmental plasticity in hemiparetic children after perinatal stroke.
    Human brain mapping, 2017, Volume: 38, Issue:3

    Topics: Adolescent; Analysis of Variance; Aspartic Acid; Cerebral Palsy; Child; Choline; Female; Glutamic Acid; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Motor Activity; Motor Cortex; Oxygen; Proton Magnetic Resonance Spectroscopy; Stroke; Young Adult

2017
1H/13C MR spectroscopic imaging of regionally specific metabolic alterations after experimental stroke.
    Brain : a journal of neurology, 2008, Volume: 131, Issue:Pt 8

    Topics: Animals; Aspartic Acid; Brain; Carbon Isotopes; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Models, Animal; Neuroglia; Neurons; Neuropsychological Tests; Rats; Rats, Wistar; Stroke

2008
Metabolism of DWI lesions: implications for rescue therapy.
    International journal of stroke : official journal of the International Stroke Society, 2007, Volume: 2, Issue:4

    Topics: Acute Disease; Animals; Aspartic Acid; Cell Hypoxia; Cerebrovascular Circulation; Diffusion Magnetic Resonance Imaging; Humans; Hypoxia-Ischemia, Brain; Lactates; Oxygen Consumption; Patient Selection; Positron-Emission Tomography; Sensitivity and Specificity; Stroke

2007
Increased brain lactate during stroke-like episode in a patient with congenital disorder of glycosylation type Ia.
    Brain & development, 2009, Volume: 31, Issue:2

    Topics: Acidosis, Lactic; Aspartic Acid; Brain; Carbohydrate Metabolism, Inborn Errors; Child; Female; Fever; Glycoproteins; Glycosylation; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Mutation; Paresis; Phosphotransferases (Phosphomutases); Stroke

2009
Changes in NAA and lactate following ischemic stroke: a serial MR spectroscopic imaging study.
    Neurology, 2008, Dec-09, Volume: 71, Issue:24

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Brain; Brain Ischemia; Brain Mapping; Cell Death; Diffusion Magnetic Resonance Imaging; Disease Progression; Down-Regulation; Energy Metabolism; Female; Humans; Lactic Acid; Linear Models; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Degeneration; Stroke; Time Factors

2008
Associations between diffusion and perfusion parameters, N-acetyl aspartate, and lactate in acute ischemic stroke.
    Stroke, 2009, Volume: 40, Issue:3

    Topics: Acute Disease; Aspartic Acid; Brain Ischemia; Cell Death; Cerebrovascular Circulation; Diffusion Magnetic Resonance Imaging; Humans; Image Processing, Computer-Assisted; Lactic Acid; Linear Models; Prospective Studies; Stroke

2009
Pathophysiologic evaluation of MELAS strokes by serially quantified MRS and CASL perfusion images.
    Brain & development, 2010, Volume: 32, Issue:2

    Topics: Adult; Aspartic Acid; Brain; Cerebrovascular Circulation; Child; Diagnostic Imaging; Female; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; MELAS Syndrome; Retrospective Studies; Spin Labels; Stroke

2010
Measurement of glutathione in normal volunteers and stroke patients at 3T using J-difference spectroscopy with minimized subtraction errors.
    Journal of magnetic resonance imaging : JMRI, 2009, Volume: 30, Issue:2

    Topics: Adult; Aspartic Acid; Biomarkers; Case-Control Studies; Choline; Creatine; Female; Glutathione; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phantoms, Imaging; Signal Processing, Computer-Assisted; Stroke; Subtraction Technique

2009
Effects of antidepressant treatment on N-acetyl aspartate and choline levels in the hippocampus and thalami of post-stroke depression patients: a study using (1)H magnetic resonance spectroscopy.
    Psychiatry research, 2010, Apr-30, Volume: 182, Issue:1

    Topics: Aged; Analysis of Variance; Antidepressive Agents; Aspartic Acid; Brain Mapping; Case-Control Studies; Choline; Depression; Dose-Response Relationship, Drug; Female; Functional Laterality; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Paroxetine; Stroke; Thalamus; Tritium

2010
Glutamate level detection by magnetic resonance spectroscopy in patients with post-stroke depression.
    European archives of psychiatry and clinical neuroscience, 2012, Volume: 262, Issue:1

    Topics: Aged; Aspartic Acid; Brain; Brain Mapping; Creatine; Depression; Female; Glutamic Acid; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Psychiatric Status Rating Scales; Stroke

2012
Motor and premotor cortices in subcortical stroke: proton magnetic resonance spectroscopy measures and arm motor impairment.
    Neurorehabilitation and neural repair, 2013, Volume: 27, Issue:5

    Topics: Adult; Aged; Aspartic Acid; Female; Functional Laterality; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Cortex; Movement Disorders; Protons; Radionuclide Imaging; Statistics as Topic; Stroke

2013
Reversible loss of N-acetyl-aspartate in rats subjected to long-term focal cerebral ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:4

    Topics: Animals; Aspartic Acid; Brain Ischemia; Chromatography, High Pressure Liquid; Chronic Disease; Male; Neuroglia; Neurons; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Stroke

2003
A newborn piglet study of moderate hypoxic-ischemic brain injury by 1H-MRS and MRI.
    Magnetic resonance imaging, 2004, Volume: 22, Issue:4

    Topics: Animals; Animals, Newborn; Aspartic Acid; Basal Ganglia; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Energy Metabolism; Hydrogen; Hydrogen-Ion Concentration; Hypoxia-Ischemia, Brain; Ischemic Attack, Transient; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Phosphocreatine; Phosphorus Isotopes; Radiopharmaceuticals; Severity of Illness Index; Stroke; Swine

2004
Time course of NAA T2 and ADC(w) in ischaemic stroke patients: 1H MRS imaging and diffusion-weighted MRI.
    Journal of the neurological sciences, 2004, May-15, Volume: 220, Issue:1-2

    Topics: Aged; Analysis of Variance; Aspartic Acid; Brain Ischemia; Brain Mapping; Diffusion Magnetic Resonance Imaging; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Sensitivity and Specificity; Stroke; Tritium

2004
Multiple spin-echo spectroscopic imaging for rapid quantitative assessment of N-acetylaspartate and lactate in acute stroke.
    Magnetic resonance in medicine, 2004, Volume: 52, Issue:2

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Analysis of Variance; Aspartic Acid; Case-Control Studies; Electron Spin Resonance Spectroscopy; Female; Humans; Lactic Acid; Linear Models; Male; Middle Aged; Middle Cerebral Artery; Signal Processing, Computer-Assisted; Stroke

2004
Reduced prefrontal N-acetylaspartate in stroke patients with apathy.
    Journal of the neurological sciences, 2005, Nov-15, Volume: 238, Issue:1-2

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Depression; Female; Functional Laterality; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motivation; Prefrontal Cortex; Psychiatric Status Rating Scales; Stroke

2005
Prefrontal N-acetylaspartate and poststroke recovery: a longitudinal proton spectroscopy study.
    AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:3

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain Ischemia; Creatine; Female; Follow-Up Studies; Functional Laterality; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Protons; Recovery of Function; Stroke

2007
Relating MRI changes to motor deficit after ischemic stroke by segmentation of functional motor pathways.
    Stroke, 2000, Volume: 31, Issue:3

    Topics: Adult; Aged; Aspartic Acid; Brain Ischemia; Disability Evaluation; Female; Humans; Internal Capsule; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Movement Disorders; Neural Pathways; Pyramidal Tracts; Stroke

2000
Correlating magnetic resonance imaging markers of axonal injury and demyelination in motor impairment secondary to stroke and multiple sclerosis.
    Magnetic resonance imaging, 2000, Volume: 18, Issue:4

    Topics: Adult; Aged; Aspartic Acid; Axons; Female; Functional Laterality; Humans; Internal Capsule; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Movement Disorders; Multiple Sclerosis; Myelin Sheath; Stroke

2000
N-acetylaspartate distribution in proton spectroscopic images of ischemic stroke: relationship to infarct appearance on T2-weighted magnetic resonance imaging.
    Stroke, 2000, Volume: 31, Issue:12

    Topics: Acute Disease; Aspartic Acid; Brain; Brain Ischemia; Cerebral Infarction; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Stroke

2000
Neurologic course of congenital disorders of glycosylation.
    Journal of child neurology, 2001, Volume: 16, Issue:6

    Topics: Aspartic Acid; Brain; Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Congenital Disorders of Glycosylation; Developmental Disabilities; Epilepsy; Female; Humans; Infant; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Degeneration; Neurologic Examination; Stroke

2001