Page last updated: 2024-08-24

n-acetylaspartic acid and Psychotic Disorders

n-acetylaspartic acid has been researched along with Psychotic Disorders in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.03)18.2507
2000's9 (27.27)29.6817
2010's20 (60.61)24.3611
2020's3 (9.09)2.80

Authors

AuthorsStudies
Bissonnette, JN; Crocker, CE; Fisher, DJ; Francis, AM; MacNeil, S; Tibbo, PG1
Howes, O; Onwordi, EC; Osugo, M; Shatalina, E; Townsend, L; Vava, R; Whitehurst, TS1
Chen, X; Du, F; Kuan, E; Ongur, D1
de la Fuente-Sandoval, C; Graff-Guerrero, A; Jung-Cook, H; León-Ortiz, P; Mao, X; Reyes-Madrigal, F; Rodríguez-Mayoral, O; Shungu, DC; Solís-Vivanco, R1
Denney, TS; Gawne, TJ; Lahti, AC; Reid, MA; Salibi, N; White, DM1
Guadagno, E; Li, C; Ramamurthy, J; Trakadis, Y; Wang, A; Wang, C; Zhang, E1
Gonzales, SS; Kraguljac, NV; Lahti, AC; Morgan, CJ; Sivaraman, S; White, DM1
Barker, PB; Coughlin, JM; Crawford, JL; DuBois, SL; Nestadt, G; Nucifora, FC; Nucifora, LG; Pradhan, S; Sawa, A; Schretlen, DJ; Sedlak, TW; Trivedi, A; Wang, AM1
Chen, X; Du, F; Fan, X; Huynh, P; Lewandowski, KE; Öngür, D1
Abe, O; Aoki, Y; Gonoi, W; Inoue, H; Iwashiro, N; Kasai, K; Katsura, M; Koike, S; Natsubori, T; Sasaki, H; Takano, Y; Takao, H; Yahata, N; Yamasue, H1
Fam, J; Furby, H; Howes, OD; Hughes, E; Morgan, C; Pepper, F; Stone, JM1
Howells, FM; Meintjes, E; Sinclair, H; Stein, DJ; Temmingh, H; Uhlmann, A; Wilson, D1
Bernier, DC; Crocker, CE; Hanstock, CC; Lakusta, B; Purdon, SE; Seres, P; Tibbo, PG1
Cohen, BM; Du, F; Goldbach, JR; Lewandowski, KE; Ongür, D; Sehovic, S; Sperry, SH1
Akhadov, TA; Dmitrienko, DM; Kaleda, VG; Kanonovich, PS; Lebedeva, IS; Omelchenko, MA; Semenova, NA; Shendyapina, MV; Simonova, OA; Ublinsky, MV1
Amminger, GP; Basu, S; Dietzek, M; Gaser, C; Gussew, A; Lorenz, C; Maitra, R; McGorry, P; Nenadic, I; Reichenbach, JR; Sauer, H; Schönfeld, N; Smesny, S1
Chavez, S; de la Fuente-Sandoval, C; Gómez-Cruz, G; Graff-Guerrero, A; León-Ortiz, P; Plitman, E; Reyes-Madrigal, F1
Kraguljac, NV; Lahti, AC; Reid, MA; White, DM1
Aleman, A; Bais, L; de Vos, A; Dlabac-De Lange, J; Knegtering, H; Liemburg, E; Opmeer, E; Pijnenborg, G; Sibeijn-Kuiper, A; van der Velde, J; Wunderink, L1
Barker, PB; Brandt, AS; Churchill, G; Edden, RA; Harris, AD; Hua, J; Lim, IA; Margolis, RL; Pradhan, S; Ross, CA; Unschuld, PG; van Zijl, PC1
Antonius, D; Berns, A; Chao, MV; Goetz, R; Gonen, O; Harroch, S; Hasan, S; Heguy, A; Kranz, TM; Lazar, M; Malaspina, D; Mazgaj, R; Rothman, K1
Aleman, A; Bais, L; Ćurčić-Blake, B; de Vos, AE; Knegtering, H; Larabi, DI; Liemburg, EJ; Pijnenborg, GH; Sibeijn-Kuiper, A1
Hermens, DF; Hickie, IB; Lagopoulos, J; Naismith, SL; Tobias-Webb, J1
Ashby, CR; Isoda, H; Iyo, M; Kawai, M; Minabe, Y; Mori, N; Sakahara, H; Sekine, Y; Suzuki, K; Takei, N1
Altamura, M; Antonucci, N; Bellomo, A; Bertolino, A; Blasi, G; Brudaglio, F; Callicott, JH; Goldberg, TE; Nardini, M; Scarabino, T; Sciota, D; Weinberger, DR1
Berger, G; Desmond, P; McGorry, PD; Pantelis, C; Phillips, LJ; Velakoulis, D; Wood, SJ; Yung, AR1
Cochran, SM; Morris, BJ; Pratt, JA; Reynolds, GP; Reynolds, LM1
Erfurth, A; Lüdemann, P; Michael, N; Möller, HE; Schuierer, G1
Berger, GE; Conus, P; Desmond, P; Lambert, M; McGorry, PD; Pantelis, C; Stuart, GW; Velakoulis, D; Wood, SJ1
Arango, C; Burdalo, MT; Desco, M; Moreno, DM; Parellada, M; Reig, S; Robles, O; Sánchez-González, J; Zabala, A1
Berger, GE; McConchie, M; McGorry, PD; Pantelis, C; Proffitt, T; Velakoulis, D; Wellard, RM; Wood, SJ1
Cohen, BM; Gruber, S; Renshaw, PF; Tohen, M; Yurgelun-Todd, DA1
Maier, M; Mellers, J; Ron, MA; Toone, B; Trimble, M1

Reviews

3 review(s) available for n-acetylaspartic acid and Psychotic Disorders

ArticleYear
Glutamate and N-Acetylaspartate Alterations Observed in Early Phase Psychosis: A Systematic Review of Proton Magnetic Resonance Spectroscopy Studies.
    Psychiatry research. Neuroimaging, 2022, Volume: 321

    Topics: Aspartic Acid; Female; Glutamic Acid; Glutamine; Humans; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders

2022
Proton Magnetic Resonance Spectroscopy of N-acetyl Aspartate in Chronic Schizophrenia, First Episode of Psychosis and High-Risk of Psychosis: A Systematic Review and Meta-Analysis.
    Neuroscience and biobehavioral reviews, 2020, Volume: 119

    Topics: Aspartic Acid; Choline; Humans; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia

2020
Metabolomics in patients with psychosis: A systematic review.
    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2018, Volume: 177, Issue:6

    Topics: 3-Hydroxybutyric Acid; Aspartic Acid; Biomarkers; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutathione; Humans; Kynurenine; Lactic Acid; Linoleic Acid; Male; Metabolome; Metabolomics; Psychotic Disorders; Schizophrenia; Serine; Tryptophan

2018

Other Studies

30 other study(ies) available for n-acetylaspartic acid and Psychotic Disorders

ArticleYear
N-acetylaspartate concentration in psychotic disorders: T2-relaxation effects.
    Schizophrenia research, 2021, Volume: 232

    Topics: Aspartic Acid; Choline; Creatine; Humans; Magnetic Resonance Spectroscopy; Neurons; Psychotic Disorders

2021
Prefrontal and Striatal Gamma-Aminobutyric Acid Levels and the Effect of Antipsychotic Treatment in First-Episode Psychosis Patients.
    Biological psychiatry, 2018, 03-15, Volume: 83, Issue:6

    Topics: Adolescent; Adult; Antipsychotic Agents; Aspartic Acid; Corpus Striatum; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Young Adult

2018
7T Proton Magnetic Resonance Spectroscopy of the Anterior Cingulate Cortex in First-Episode Schizophrenia.
    Schizophrenia bulletin, 2019, 01-01, Volume: 45, Issue:1

    Topics: Adult; Aspartic Acid; Cognitive Dysfunction; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia; Young Adult

2019
Neurometabolic abnormalities in the associative striatum in antipsychotic-naïve first episode psychosis patients.
    Psychiatry research. Neuroimaging, 2018, 11-30, Volume: 281

    Topics: Adolescent; Adult; Aspartic Acid; Biomarkers; Case-Control Studies; Choline; Corpus Striatum; Disease Progression; Dopamine; Female; Glutamic Acid; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia; Young Adult

2018
Assessing Brain Metabolism With 7-T Proton Magnetic Resonance Spectroscopy in Patients With First-Episode Psychosis.
    JAMA psychiatry, 2019, 03-01, Volume: 76, Issue:3

    Topics: Aspartic Acid; Brain; Case-Control Studies; Cross-Sectional Studies; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Male; Neuropsychological Tests; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Young Adult

2019
Role of glia in prefrontal white matter abnormalities in first episode psychosis or mania detected by diffusion tensor spectroscopy.
    Schizophrenia research, 2019, Volume: 209

    Topics: Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Diffusion Tensor Imaging; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Myelin Sheath; Neuroglia; Neurons; Prefrontal Cortex; Psychotic Disorders; Schizophrenia; White Matter; Young Adult

2019
Reduced frontal glutamate + glutamine and N-acetylaspartate levels in patients with chronic schizophrenia but not in those at clinical high risk for psychosis or with first-episode schizophrenia.
    Schizophrenia bulletin, 2014, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Aspartic Acid; Chronic Disease; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Prodromal Symptoms; Psychotic Disorders; Risk; Schizophrenia; Young Adult

2014
Glutamate, N-acetyl aspartate and psychotic symptoms in chronic ketamine users.
    Psychopharmacology, 2014, Volume: 231, Issue:10

    Topics: Adult; Aspartic Acid; Brain; Female; Glutamic Acid; Glutamine; Humans; Ketamine; Magnetic Resonance Spectroscopy; Male; Psychotic Disorders; Substance-Related Disorders; Young Adult

2014
(1)H-magnetic resonance spectroscopy ((1)H-MRS) in methamphetamine dependence and methamphetamine induced psychosis.
    Schizophrenia research, 2014, Volume: 153, Issue:1-3

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Methamphetamine; Prefrontal Cortex; Protons; Psychotic Disorders; Substance-Related Disorders; Young Adult

2014
Prefrontal glutamate levels differentiate early phase schizophrenia and methamphetamine addiction: a (1)H MRS study at 3Tesla.
    Schizophrenia research, 2014, Volume: 157, Issue:1-3

    Topics: Adolescent; Adult; Amphetamine-Related Disorders; Aspartic Acid; Glutamic Acid; Humans; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Young Adult

2014
Myelin vs axon abnormalities in white matter in bipolar disorder.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Mar-13, Volume: 40, Issue:5

    Topics: Adult; Aspartic Acid; Axons; Bipolar Disorder; Diffusion Tensor Imaging; Female; Humans; Magnetic Resonance Imaging; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Psychotic Disorders; White Matter

2015
[Information processing and brain metabolic characteristics in patients at ultra-high risk for endogenous psychosis].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:1

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Evoked Potentials; Female; Glutamic Acid; Glutamine; Humans; Male; Mental Processes; Neuroimaging; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Risk; Thalamus; Young Adult

2015
Associations of hippocampal metabolism and regional brain grey matter in neuroleptic-naïve ultra-high-risk subjects and first-episode schizophrenia.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:10

    Topics: Adolescent; Adult; Aspartic Acid; Brain Mapping; Female; Frontal Lobe; Glutamic Acid; Gray Matter; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Prodromal Symptoms; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Risk; Schizophrenia; Young Adult

2015
Elevated Myo-Inositol, Choline, and Glutamate Levels in the Associative Striatum of Antipsychotic-Naive Patients With First-Episode Psychosis: A Proton Magnetic Resonance Spectroscopy Study With Implications for Glial Dysfunction.
    Schizophrenia bulletin, 2016, Volume: 42, Issue:2

    Topics: Adult; Aspartic Acid; Choline; Corpus Striatum; Glutamic Acid; Glutamine; Humans; Inositol; Neuroglia; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia

2016
A combined diffusion tensor imaging and magnetic resonance spectroscopy study of patients with schizophrenia.
    Schizophrenia research, 2016, Volume: 170, Issue:2-3

    Topics: Adult; Antipsychotic Agents; Aspartic Acid; Creatine; Diffusion Tensor Imaging; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Multimodal Imaging; Myelin Sheath; Psychotic Disorders; Schizophrenia; White Matter

2016
Prefrontal NAA and Glx Levels in Different Stages of Psychotic Disorders: a 3T 1H-MRS Study.
    Scientific reports, 2016, Feb-23, Volume: 6

    Topics: Adolescent; Adult; Age Factors; Antipsychotic Agents; Aspartic Acid; Case-Control Studies; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Male; Middle Aged; Neurotransmitter Agents; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Regression Analysis; Risk; Severity of Illness Index; Time Factors

2016
Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla.
    Schizophrenia research, 2016, Volume: 172, Issue:1-3

    Topics: Adult; Aging; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Gyrus Cinguli; Humans; Inositol; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia

2016
Prefrontal neuronal integrity predicts symptoms and cognition in schizophrenia and is sensitive to genetic heterogeneity.
    Schizophrenia research, 2016, Volume: 172, Issue:1-3

    Topics: Adult; Aspartic Acid; Cognition; Female; Humans; Intelligence Tests; Magnetic Resonance Imaging; Male; Membrane Proteins; Mutation, Missense; Nerve Tissue Proteins; Polymorphism, Genetic; Prefrontal Cortex; Psychiatric Status Rating Scales; Psychotic Disorders; Receptor-Like Protein Tyrosine Phosphatases, Class 5; Schizophrenia; Schizophrenic Psychology

2016
Association between prefrontal N-acetylaspartate and insight in psychotic disorders.
    Schizophrenia research, 2017, Volume: 179

    Topics: Adult; Aspartic Acid; Awareness; Comprehension; Executive Function; Female; Humans; Male; Metacognition; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Young Adult

2017
Distinct neurometabolic profiles are evident in the anterior cingulate of young people with major psychiatric disorders.
    Translational psychiatry, 2012, May-08, Volume: 2

    Topics: Adolescent; Adult; Aspartic Acid; Case Management; Combined Modality Therapy; Energy Metabolism; Female; Glutamic Acid; Glutathione; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Psychotic Disorders; Psychotropic Drugs; Reference Values; Young Adult

2012
Metabolite alterations in basal ganglia associated with methamphetamine-related psychiatric symptoms. A proton MRS study.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 27, Issue:3

    Topics: Adult; Analysis of Variance; Aspartic Acid; Basal Ganglia; Central Nervous System Stimulants; Choline; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Methamphetamine; Phosphocreatine; Psychiatric Status Rating Scales; Psychotic Disorders

2002
Working memory deficits and levels of N-acetylaspartate in patients with schizophreniform disorder.
    The American journal of psychiatry, 2003, Volume: 160, Issue:3

    Topics: Adult; Aspartic Acid; Creatine; Female; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Memory Disorders; Neuropsychological Tests; Prefrontal Cortex; Psychotic Disorders

2003
Proton magnetic resonance spectroscopy in first episode psychosis and ultra high-risk individuals.
    Schizophrenia bulletin, 2003, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain Mapping; Choline; Creatine; Depressive Disorder, Major; Dominance, Cerebral; Energy Metabolism; Female; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Net; Prefrontal Cortex; Psychotic Disorders; Reference Values; Risk; Schizophrenia; Schizotypal Personality Disorder; Temporal Lobe

2003
Chronic phencyclidine administration induces schizophrenia-like changes in N-acetylaspartate and N-acetylaspartylglutamate in rat brain.
    Schizophrenia research, 2005, Mar-01, Volume: 73, Issue:2-3

    Topics: Animals; Aspartic Acid; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Frontal Lobe; Hallucinogens; Hippocampus; Male; Phencyclidine; Psychotic Disorders; Rats; Rats, Long-Evans; Temporal Lobe

2005
Serial proton spectroscopy in a case of adult-onset subacute sclerosing panencephalitis.
    Psychiatry research, 2005, Aug-30, Volume: 139, Issue:3

    Topics: Adult; Aspartic Acid; Choline; Electroconvulsive Therapy; Humans; Immunologic Factors; Inositol; Interferon-alpha; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Psychotic Disorders; Subacute Sclerosing Panencephalitis

2005
Prediction of functional outcome 18 months after a first psychotic episode: a proton magnetic resonance spectroscopy study.
    Archives of general psychiatry, 2006, Volume: 63, Issue:9

    Topics: Adult; Aspartic Acid; Choline; Creatine; Female; Follow-Up Studies; Functional Laterality; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Outcome Assessment, Health Care; Patient Readmission; Phosphocreatine; Predictive Value of Tests; Prefrontal Cortex; Prognosis; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Temporal Lobe

2006
Findings of proton magnetic resonance spectometry in the dorsolateral prefrontal cortex in adolescents with first episodes of psychosis.
    Psychiatry research, 2007, Oct-15, Volume: 156, Issue:1

    Topics: Adolescent; Aspartic Acid; Child; Choline; Creatine; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons; Psychotic Disorders; Radiography; Water

2007
A 1H-MRS investigation of the medial temporal lobe in antipsychotic-naïve and early-treated first episode psychosis.
    Schizophrenia research, 2008, Volume: 102, Issue:1-3

    Topics: Adult; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Female; Frontal Lobe; Functional Laterality; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Psychotic Disorders; Schizophrenia; Temporal Lobe

2008
Temporal lobe proton magnetic resonance spectroscopy of patients with first-episode psychosis.
    The American journal of psychiatry, 1995, Volume: 152, Issue:3

    Topics: Adult; Aspartic Acid; Choline; Creatinine; Female; Functional Laterality; Humans; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Psychotic Disorders; Temporal Lobe

1995
Schizophrenia, temporal lobe epilepsy and psychosis: an in vivo magnetic resonance spectroscopy and imaging study of the hippocampus/amygdala complex.
    Psychological medicine, 2000, Volume: 30, Issue:3

    Topics: Adult; Amygdala; Aspartic Acid; Case-Control Studies; Epilepsy, Temporal Lobe; Female; Functional Laterality; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychotic Disorders; Schizophrenia

2000