Page last updated: 2024-08-24

n-acetylaspartic acid and Pregnancy

n-acetylaspartic acid has been researched along with Pregnancy in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (28.57)18.2507
2000's21 (42.86)29.6817
2010's14 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Basu, SK; Chang, T; Kapse, K; Limperopoulos, C; McCarter, R; Murnick, J; Pradhan, S1
Alladi, S; Griffiths, PD; Hart, AR; Paley, MN; Smith, MF; Whitby, EH; Wilkinson, S1
Cady, EB; Raivich, G; Robertson, NJ; Thayyil, S1
Huang, QJ; Peng, H; Shao, Y; Wu, R; Xu, H; Xuan, Y; Yan, G1
Carbajo, RJ; González-Tendero, A; Gratacós, E; Illa, M; Muñoz-Moreno, E; Pineda-Lucena, A; Sanz-Cortés, M; Simões, RV1
Basil, P; Chua, SE; Ho, LC; Kong, W; Lam, S; Law, AC; Leung, YO; Li, Q; McAlonan, GM; Sham, PC; Wei, R; Wu, EX; Zhang, X; Zhou, I1
Chege, W; Cooper, JD; Kapur, S; Lythgoe, DJ; So, PW; Vernon, AC; Williams, SC1
Adams Waldorf, KM; Armistead, B; Baldessari, A; Boldenow, E; Davis, MA; Dewey, EC; Diamond, MS; Dighe, MK; Dobyns, WB; English, C; Fairgrieve, MR; Gale, M; Garden, GA; Gatenby, JC; Gough, GM; Grant, RF; Green, RR; Hevner, RF; Juul, SE; Kapur, RP; Kuller, L; Lee, W; Merillat, S; Ogle, J; Rajagopal, L; Richards, T; Shaw, DW; Stencel-Baerenwald, JE; Studholme, C; Thiel, J; Tisoncik-Go, J; Vornhagen, J1
Galloway, MP; Hannigan, JH; McMechan, AP; O'Leary-Moore, SK1
Ahmad, AM; Al-Dirbashi, OY; Al-Nemer, M; Al-Sayed, M; Imtiaz, F; Kurdi, W; Rashed, MS; Tulbah, M1
Bowen-Roberts, T; Brant, R; Chau, V; McFadden, DE; Miller, SP; Poskitt, KJ; Sargent, MA; Soulikias, W; Synnes, A1
Annese, D; Brown, DW; du Plessis, AJ; Dunbar-Masterson, C; Geva, J; Guizard, N; Laussen, PC; Limperopoulos, C; McElhinney, DB; McGrath, E; Newburger, JW; Robertson, RL; Trainor, B; Tworetzky, W1
Girard, N1
Connolly, DJ; Khan, R; Mordekar, SR; Nandish, S; Rittey, CD1
Anbeek, P; Benders, MJ; De Vries, LS; Groenendaal, F; Van Haastert, IC; Van Kooij, BJ1
Allen, PS; Baker, GB; Burgess, DT; Hanstock, CC; Khalili, P; Khudabux-Der, J; LeMelledo, JM; McEwen, AM; Mitchell, ND; Newman, SC; Seres, P1
Berger-Kulemann, V; Brugger, PC; Krssak, M; Prayer, D; Pugash, D; Weber, M; Wielandner, A1
Bertolino, A; Lipska, BK; Olson, A; Roffman, JL; van Gelderen, P; Weinberger, DR1
Heerschap, A; Kok, RD; Nijland, R; van den Berg, PP; van den Bergh, AJ1
Crawshaw, S; Moody, A; Rubin, PC; Rutherford, JM1
Heerschap, A; Kok, RD; van den Berg, PP1
Celik, O; Hascalik, S1
Georgieff, MK; Gruetter, R; Rao, R; Tkac, I; Townsend, EL1
Geyer, MA; Harte, MK; Powell, SB; Reynolds, GP; Reynolds, LM; Swerdlow, NR1
Ennis, K; Georgieff, MK; Gruetter, R; Raman, L; Rao, R; Tkac, I1
Anés, M; da Silva, LF; Höefel Filho, JR; Nunes, ML1
Chaumoitre, K; Cozzone, PJ; D'Ercole, C; Figarella-Branger, D; Girard, N; Gire, C; Gouny, SC; Le Fur, Y; Viola, A; Viout, P1
Autti-Rämö, I; Fagerlund, A; Heikkinen, S; Korkman, M; Kuusi, T; Lundbom, N; Riley, EP; Timonen, M1
Amanda Shen, Z; Barnett, JF; Delaney, B; Gannon, S; Maxwell, C; Munley, SA; Powley, CR1
Alvarado, A; Azpurua, H; Copel, JA; Guevara-Zuloaga, F; Mayobre, F; Salom, T1
Anikster, Y; Elpeleg, ON; Jakobs, C; Shaag, A1
Bennett, MJ; Divry, P; Elpeleg, ON; Gibson, KM; Jakobs, C; Rinaldo, P; Rolland, MO; Sherwood, WG1
Kelley, RI1
Hori, E; Kato, T; Matsushita, K; Mito, T; Nishina, M; Takashima, S1
Das, K; Dhanuka, AK; Gupta, RK; Roy, R; Sengar, AR1
Baslow, MH; Resnik, TR1
Buist, R; Dawood, MR; Del Bigio, MR; Johnston, JB; Ni, W; Peeling, J; Power, C1
Bascaramurty, S; Kozlowski, P; Malisza, KL; Ning, G; Tuor, UI1
Besley, GT; Elpeleg, ON; Jakobs, C; Manning, NJ; Shaag, A; Walter, JH1
Matalon, R1
Kinney, DK; Renshaw, PF; Steingard, RJ; Yurgelun-Todd, DA1
Chang, L; Ernst, T; Gilbride, K; Kuo, J; Poland, RE; Smith, LM; Walot, I; Yonekura, ML1
Barkovich, AJ; Ferriero, DM; Gregory, G; Henry, RG; Lu, Y; Noworolski, SM; Partridge, JC; Vigneron, DB; von dem Bussche, M1
Gordon, N1
Barker, PB; Beauchamp, NJ; Eichler, FS; Wang, P; Wityk, RJ1
Gashkoff, P; Kaul, R; Matalon, R; Michals, K1
Divry, P; Jakobs, C; Rolland, MO; ten Brink, HJ1
al Aqeel, A; al Odaib, A; Cook, JD; Feryal, RR; Gascon, GG; Gleispach, H; Leis, HJ; Nester, MJ; Ozand, PT1
Jakobs, C; Kleijer, WJ; Langelaar, SA; Macek, M; Srsen, S; Srsnová, K; Stellaard, F; ten Brink, HJ; Zee, T1

Reviews

5 review(s) available for n-acetylaspartic acid and Pregnancy

ArticleYear
Magnetic resonance spectroscopy biomarkers in term perinatal asphyxial encephalopathy: from neuropathological correlates to future clinical applications.
    Current pediatric reviews, 2014, Volume: 10, Issue:1

    Topics: Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Biomarkers; Choline; Creatine; Disease Models, Animal; Female; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Lactic Acid; Magnetic Resonance Spectroscopy; Neuroprotective Agents; Pregnancy; Sensitivity and Specificity; Swine

2014
[Magnetic resonance spectroscopy for cerebral imaging].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2010, Volume: 17, Issue:6

    Topics: Apoptosis; Aspartic Acid; Asphyxia Neonatorum; Biomarkers, Tumor; Brain; Brain Diseases; Brain Diseases, Metabolic; Brain Diseases, Metabolic, Inborn; Brain Neoplasms; Child; Child, Preschool; Choline; Creatine; Energy Metabolism; Female; Humans; Hypoxia, Brain; Infant; Infant, Newborn; Lactic Acid; Magnetic Resonance Spectroscopy; Neurons; Pregnancy; Sensitivity and Specificity

2010
Canavan disease. Analysis of the nature of the metabolic lesions responsible for development of the observed clinical symptoms.
    Journal of molecular neuroscience : MN, 1997, Volume: 9, Issue:2

    Topics: Amidohydrolases; Animals; Aspartic Acid; Canavan Disease; Central Nervous System; Female; Fetal Diseases; Histidine; Humans; Pregnancy

1997
Canavan disease: diagnosis and molecular analysis.
    Genetic testing, 1997, Volume: 1, Issue:1

    Topics: Amidohydrolases; Aspartic Acid; Canavan Disease; Cloning, Molecular; Diagnosis, Differential; Female; Gene Frequency; Genetic Carrier Screening; Genetic Testing; Humans; Jews; Male; Mutation; Pregnancy; Prenatal Diagnosis

1997
Canavan disease: a review of recent developments.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2001, Volume: 5, Issue:2

    Topics: Amidohydrolases; Aspartic Acid; Canavan Disease; Female; Genetic Therapy; Humans; Infant; Infant, Newborn; Pregnancy; Prenatal Diagnosis; Prognosis

2001

Trials

1 trial(s) available for n-acetylaspartic acid and Pregnancy

ArticleYear
Prognostic value of 1H-MRS in neonatal encephalopathy.
    Pediatric neurology, 2006, Volume: 34, Issue:5

    Topics: Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Choline; Creatine; Creatinine; Female; Follow-Up Studies; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Polysomnography; Predictive Value of Tests; Pregnancy; Pregnancy Complications; Prognosis; Protons; Risk Factors; Thalamus

2006

Other Studies

43 other study(ies) available for n-acetylaspartic acid and Pregnancy

ArticleYear
Third Trimester Cerebellar Metabolite Concentrations are Decreased in Very Premature Infants with Structural Brain Injury.
    Scientific reports, 2019, 02-04, Volume: 9, Issue:1

    Topics: Aspartic Acid; Brain; Brain Injuries; Cerebellum; Choline; Creatine; Female; Gestational Age; Gray Matter; Humans; Infant; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Pregnancy; Pregnancy Trimester, Third; Premature Birth; Proton Magnetic Resonance Spectroscopy

2019
Diffusion-weighted imaging and magnetic resonance proton spectroscopy following preterm birth.
    Clinical radiology, 2014, Volume: 69, Issue:8

    Topics: Abnormalities, Multiple; Aspartic Acid; Brain; Brain Chemistry; Brain Mapping; Cohort Studies; Developmental Disabilities; Diffusion Magnetic Resonance Imaging; Ductus Arteriosus, Patent; Female; Humans; Infant; Infant, Premature; Infant, Premature, Diseases; Magnetic Resonance Spectroscopy; Male; Myelin Sheath; Nerve Fibers, Myelinated; Pregnancy; Premature Birth; Prospective Studies

2014
Chronic social isolation decreases glutamate and glutamine levels and induces oxidative stress in the rat hippocampus.
    Behavioural brain research, 2015, Apr-01, Volume: 282

    Topics: Animals; Aspartic Acid; Catalase; Cerebral Cortex; Energy Metabolism; Female; Glutamic Acid; Glutamine; Glutathione Peroxidase; Hippocampus; Hydrogen Peroxide; Magnetic Resonance Spectroscopy; Male; Oxidative Stress; Phosphocreatine; Prefrontal Cortex; Pregnancy; Rats; Rats, Sprague-Dawley; Social Isolation; Superoxide Dismutase

2015
In Vivo Detection of Perinatal Brain Metabolite Changes in a Rabbit Model of Intrauterine Growth Restriction (IUGR).
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Animals; Animals, Newborn; Aspartic Acid; Biomarkers; Birth Weight; Brain; Cerebral Cortex; Corpus Striatum; Female; Fetal Growth Retardation; Gestational Age; Glycine; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Models, Animal; Parturition; Pregnancy; Rabbits; Stillbirth

2015
Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model.
    Translational psychiatry, 2015, Sep-22, Volume: 5

    Topics: Animals; Aspartic Acid; Behavior, Animal; Creatine; Diet, High-Fat; Dietary Supplements; Fatty Acids, Omega-3; Female; Gyrus Cinguli; Inflammation; Inositol; Male; Mice; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prepulse Inhibition; Protective Agents; Weaning

2015
Longitudinal in vivo maturational changes of metabolites in the prefrontal cortex of rats exposed to polyinosinic-polycytidylic acid in utero.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:12

    Topics: Age Factors; Animals; Aspartic Acid; Female; Gestational Age; Glutamic Acid; Glutathione; Interferon Inducers; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Poly I-C; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Protons; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Taurine

2015
Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate.
    Nature medicine, 2016, Volume: 22, Issue:11

    Topics: Animals; Aspartic Acid; Brain; Choline; Creatine; Echoencephalography; Female; Fetus; Glutamic Acid; Glutamine; Inositol; Macaca nemestrina; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Pregnancy; Pregnancy Complications, Infectious; RNA, Viral; Ultrasonography, Prenatal; Zika Virus; Zika Virus Infection

2016
Neonatal alcohol-induced region-dependent changes in rat brain neurochemistry measured by high-resolution magnetic resonance spectroscopy.
    Alcoholism, clinical and experimental research, 2008, Volume: 32, Issue:10

    Topics: Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Body Weight; Cerebellum; Cerebrum; Choline; Ethanol; Female; Male; Pregnancy; Rats; Taurine

2008
Reliable prenatal diagnosis of Canavan disease by measuring N-acetylaspartate in amniotic fluid using liquid chromatography tandem mass spectrometry.
    Prenatal diagnosis, 2009, Volume: 29, Issue:5

    Topics: Amidohydrolases; Amniotic Fluid; Aspartic Acid; Canavan Disease; Case-Control Studies; Chromatography, Liquid; Female; Gestational Age; Humans; Mutation; Pregnancy; Prenatal Diagnosis; Reproducibility of Results; Risk Factors; Tandem Mass Spectrometry

2009
Effect of chorioamnionitis on brain development and injury in premature newborns.
    Annals of neurology, 2009, Volume: 66, Issue:2

    Topics: Anisotropy; Aspartic Acid; Brain; Brain Diseases; Choline; Chorioamnionitis; Diffusion Magnetic Resonance Imaging; Female; Humans; Hypotension; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infections; Male; Nerve Fibers, Myelinated; Placenta; Pregnancy; Protons; Risk Factors

2009
Brain volume and metabolism in fetuses with congenital heart disease: evaluation with quantitative magnetic resonance imaging and spectroscopy.
    Circulation, 2010, Jan-05, Volume: 121, Issue:1

    Topics: Aspartic Acid; Brain; Choline; Female; Gestational Age; Heart Defects, Congenital; Humans; Imaging, Three-Dimensional; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Pregnancy; Prenatal Diagnosis; Prospective Studies; Protons

2010
Reversible parainfectious bilateral "striatal necrosis".
    Pediatric neurology, 2012, Volume: 46, Issue:1

    Topics: Aspartic Acid; Child, Preschool; Corpus Striatum; Encephalomyelitis; Female; Functional Laterality; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Necrosis; Pregnancy; Pregnancy Complications

2012
Cerebellar volume and proton magnetic resonance spectroscopy at term, and neurodevelopment at 2 years of age in preterm infants.
    Developmental medicine and child neurology, 2012, Volume: 54, Issue:3

    Topics: Aspartic Acid; Brain Mapping; Cerebellum; Child, Preschool; Choline; Cognition Disorders; Developmental Disabilities; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Pregnancy; Premature Birth; Protons

2012
Increased glutamate levels in the medial prefrontal cortex in patients with postpartum depression.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:11

    Topics: Adult; Aspartic Acid; Case-Control Studies; Creatine; Depression, Postpartum; Female; Glutamic Acid; Glycerylphosphorylcholine; Humans; Magnetic Resonance Spectroscopy; Phosphorylcholine; Prefrontal Cortex; Pregnancy; Time Factors; Young Adult

2012
MR spectroscopy of the fetal brain: is it possible without sedation?
    AJNR. American journal of neuroradiology, 2013, Volume: 34, Issue:2

    Topics: Aspartic Acid; Brain; Choline; Conscious Sedation; Creatine; Female; Fetal Diseases; Fetal Growth Retardation; Gestational Age; Humans; Inositol; Labor Presentation; Magnetic Resonance Spectroscopy; Movement; Pregnancy; Prenatal Diagnosis; Protons; Retrospective Studies; Signal-To-Noise Ratio

2013
Reduced N-acetylaspartate in prefrontal cortex of adult rats with neonatal hippocampal damage.
    Cerebral cortex (New York, N.Y. : 1991), 2002, Volume: 12, Issue:9

    Topics: Age Factors; Aging; Animals; Animals, Newborn; Aspartic Acid; Female; Hippocampus; Male; Motor Activity; Neurons; Nuclear Magnetic Resonance, Biomolecular; Prefrontal Cortex; Pregnancy; Rats; Rats, Sprague-Dawley

2002
Maturation of the human fetal brain as observed by 1H MR spectroscopy.
    Magnetic resonance in medicine, 2002, Volume: 48, Issue:4

    Topics: Aspartic Acid; Brain; Choline; Creatine; Dipeptides; Female; Fetus; Gestational Age; Humans; Inositol; Magnetic Resonance Spectroscopy; Pregnancy

2002
Magnetic resonance spectroscopy in pre-eclampsia: evidence of cerebral ischaemia.
    BJOG : an international journal of obstetrics and gynaecology, 2003, Volume: 110, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Brain Ischemia; Cerebral Arteries; Constriction, Pathologic; Female; Humans; Magnetic Resonance Angiography; Magnetic Resonance Spectroscopy; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Prospective Studies

2003
Antenatal proton MR spectroscopy of the human brain in vivo.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2003, Volume: 19, Issue:7-8

    Topics: Aspartic Acid; Brain; Choline; Creatine; Female; Fetus; Gestational Age; Humans; Inositol; Magnetic Resonance Spectroscopy; Pregnancy; Time Factors

2003
Reversible posterior leukoencephalopathy in eclampsia.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2003, Volume: 82, Issue:1

    Topics: Adult; Aspartic Acid; Cerebral Arterial Diseases; Choline; Creatine; Female; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Pregnancy; Pregnancy Complications, Cardiovascular

2003
Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus.
    The Journal of nutrition, 2003, Volume: 133, Issue:10

    Topics: Aging; Animals; Aspartic Acid; Body Weight; Brain; Brain Chemistry; Creatine; Ethanolamines; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Iron; Iron Deficiencies; Liver; Magnetic Resonance Spectroscopy; Male; Myocardium; Organ Size; Phosphocreatine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Taurine

2003
Reduced N-acetylaspartate in the temporal cortex of rats reared in isolation.
    Biological psychiatry, 2004, Aug-15, Volume: 56, Issue:4

    Topics: Animals; Animals, Newborn; Aspartic Acid; Brain Chemistry; Chromatography, High Pressure Liquid; Female; Male; Neural Inhibition; Pregnancy; Rats; Rats, Sprague-Dawley; Social Isolation; Temporal Lobe

2004
In vivo effect of chronic hypoxia on the neurochemical profile of the developing rat hippocampus.
    Brain research. Developmental brain research, 2005, May-12, Volume: 156, Issue:2

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Body Weight; Brain Chemistry; Creatine; Energy Metabolism; Female; gamma-Aminobutyric Acid; Hippocampus; Hypoxia; Iron; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Organ Size; Phosphocreatine; Pregnancy; Rats; Rats, Sprague-Dawley; Time Factors; Tritium

2005
Assessment of normal fetal brain maturation in utero by proton magnetic resonance spectroscopy.
    Magnetic resonance in medicine, 2006, Volume: 56, Issue:4

    Topics: Aging; Algorithms; Aspartic Acid; Brain; Brain Chemistry; Female; Fetal Development; Gestational Age; Humans; Linear Models; Magnetic Resonance Spectroscopy; Pregnancy

2006
Brain metabolic alterations in adolescents and young adults with fetal alcohol spectrum disorders.
    Alcoholism, clinical and experimental research, 2006, Volume: 30, Issue:12

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Case-Control Studies; Central Nervous System Depressants; Choline; Creatine; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Magnetic Resonance Spectroscopy; Male; Neuroglia; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Protons; Research Design; Severity of Illness Index

2006
Acute and repeated dose oral toxicity of N-acetyl-l-aspartic acid in Sprague-Dawley rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:6

    Topics: Administration, Oral; Animals; Aspartic Acid; Behavior, Animal; Blood Cell Count; Blood Chemical Analysis; Blood Coagulation; Body Weight; Diet; Eating; Eye; Female; Food Analysis; Male; Motor Activity; Pregnancy; Rats; Rats, Sprague-Dawley

2008
Metabolic assessment of the brain using proton magnetic resonance spectroscopy in a growth-restricted human fetus: case report.
    American journal of perinatology, 2008, Volume: 25, Issue:5

    Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Child, Preschool; Choline; Female; Fetal Growth Retardation; Fetal Hypoxia; Fetus; Follow-Up Studies; Humans; Infant, Newborn; Lactic Acid; Magnetic Resonance Spectroscopy; Pregnancy; Ultrasonography, Doppler; Ultrasonography, Prenatal; Umbilical Arteries

2008
Prenatal detection of Canavan disease (aspartoacylase deficiency) by DNA analysis.
    Journal of inherited metabolic disease, 1994, Volume: 17, Issue:6

    Topics: Amidohydrolases; Amniotic Fluid; Aspartic Acid; Base Sequence; Canavan Disease; DNA; Female; Humans; Molecular Sequence Data; Pregnancy; Prenatal Diagnosis

1994
Reliable prenatal diagnosis of Canavan disease (aspartoacylase deficiency): comparison of enzymatic and metabolite analysis.
    Journal of inherited metabolic disease, 1993, Volume: 16, Issue:5

    Topics: Amniotic Fluid; Aspartic Acid; Canavan Disease; Female; Fetal Diseases; Humans; Pregnancy; Prenatal Diagnosis

1993
Prenatal detection of Canavan disease by measurement of N-acetyl-L-aspartate in amniotic fluid.
    Journal of inherited metabolic disease, 1993, Volume: 16, Issue:5

    Topics: Adult; Amniotic Fluid; Aspartic Acid; Canavan Disease; Female; Humans; Pregnancy; Prenatal Diagnosis

1993
Neuronal maturation and N-acetyl-L-aspartic acid development in human fetal and child brains.
    Brain & development, 1997, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Chemistry; Cellular Senescence; Cerebral Cortex; Child; Child, Preschool; Female; Humans; Infant; Magnetic Resonance Spectroscopy; Neurons; Pregnancy

1997
MR imaging, MR angiography, and MR spectroscopy of the brain in eclampsia.
    AJNR. American journal of neuroradiology, 1997, Volume: 18, Issue:8

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Edema; Brain Ischemia; Cerebral Arteries; Choline; Creatine; Eclampsia; Energy Metabolism; Female; Humans; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Obstetric Labor Complications; Pregnancy; Prognosis

1997
Neurovirulence in feline immunodeficiency virus-infected neonatal cats is viral strain specific and dependent on systemic immune suppression.
    Journal of virology, 1998, Volume: 72, Issue:11

    Topics: Animals; Animals, Newborn; Aspartic Acid; Base Sequence; Brain; Cats; Cell Death; DNA Primers; DNA, Viral; Female; Humans; Immune Tolerance; Immunodeficiency Virus, Feline; Lentivirus Infections; Lymphocyte Count; Magnetic Resonance Spectroscopy; Nervous System; Neurons; Pregnancy; Species Specificity; Virulence; Virus Replication

1998
Metabolite changes in neonatal rat brain during and after cerebral hypoxia-ischemia: a magnetic resonance spectroscopic imaging study.
    NMR in biomedicine, 1999, Volume: 12, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Ischemia; Cerebral Infarction; Female; Hypoxia, Brain; Lactic Acid; Magnetic Resonance Imaging; Pregnancy; Protons; Rats; Rats, Wistar

1999
Prenatal diagnosis of Canavan disease--problems and dilemmas.
    Journal of inherited metabolic disease, 1999, Volume: 22, Issue:3

    Topics: Amidohydrolases; Amniotic Fluid; Aspartic Acid; Canavan Disease; Female; Fetal Diseases; Humans; Infant; Male; Polymerase Chain Reaction; Pregnancy; Prenatal Diagnosis

1999
Perinatal complications and abnormal proton metabolite concentrations in frontal cortex of adolescents seen on magnetic resonance spectroscopy.
    Neuropsychiatry, neuropsychology, and behavioral neurology, 2000, Volume: 13, Issue:1

    Topics: Aspartic Acid; Brain Damage, Chronic; Choline; Creatine; Female; Follow-Up Studies; Frontal Lobe; Humans; Infant, Newborn; Magnetic Resonance Spectroscopy; Neurocognitive Disorders; Obstetric Labor Complications; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects

2000
Brain proton magnetic resonance spectroscopy and imaging in children exposed to cocaine in utero.
    Pediatrics, 2001, Volume: 107, Issue:2

    Topics: Aspartic Acid; Brain; Case-Control Studies; Child; Cocaine; Creatinine; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Pregnancy; Prenatal Exposure Delayed Effects

2001
Three-dimensional proton MR spectroscopic imaging of premature and term neonates.
    AJNR. American journal of neuroradiology, 2001, Volume: 22, Issue:7

    Topics: Aspartic Acid; Brain; Brain Mapping; Cerebral Hemorrhage; Choline; Chorioamnionitis; Creatine; Energy Metabolism; Female; Gestational Age; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Infant, Newborn; Infant, Premature, Diseases; Magnetic Resonance Spectroscopy; Male; Pregnancy; Reference Values

2001
Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome.
    AJNR. American journal of neuroradiology, 2002, Volume: 23, Issue:5

    Topics: Adult; Aspartic Acid; Brain Diseases; Choline; Confusion; Creatine; Female; Headache; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Pregnancy; Pregnancy Complications; Seizures; Syndrome; Tissue Distribution; Vision Disorders

2002
Prenatal diagnosis of Canavan disease.
    Journal of inherited metabolic disease, 1992, Volume: 15, Issue:3

    Topics: Amidohydrolases; Amnion; Amniotic Fluid; Aspartic Acid; Cells, Cultured; Chorionic Villi; Female; Humans; Pregnancy; Prenatal Diagnosis

1992
Prenatal diagnosis of Canavan disease.
    European journal of pediatrics, 1992, Volume: 151, Issue:8

    Topics: Aspartic Acid; Central Nervous System Diseases; Female; Fetal Diseases; Humans; Pregnancy; Prenatal Diagnosis

1992
Prenatal detection of Canavan disease.
    Lancet (London, England), 1991, Mar-23, Volume: 337, Issue:8743

    Topics: Amniotic Fluid; Aspartic Acid; Female; Fetal Diseases; Humans; Infant, Newborn; Male; Methods; Nervous System Diseases; Pregnancy

1991
Stable isotope dilution analysis of N-acetylaspartic acid in CSF, blood, urine and amniotic fluid: accurate postnatal diagnosis and the potential for prenatal diagnosis of Canavan disease.
    Journal of inherited metabolic disease, 1991, Volume: 14, Issue:5

    Topics: Amidohydrolases; Amniotic Fluid; Aspartic Acid; Body Fluids; Female; Humans; Indicator Dilution Techniques; Infant; Pregnancy; Prenatal Diagnosis; Reference Values

1991