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n-acetylaspartic acid and Neurodegenerative Diseases

n-acetylaspartic acid has been researched along with Neurodegenerative Diseases in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's5 (35.71)29.6817
2010's7 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Butterfield, DA; Hinchie, A; Powell, DK; Ren, X; Swomley, A1
AlHashem, A; AlShahwan, S; BoAli, A; Tabarki, B; Tlili-Graiess, K; Zuccoli, G1
Confort-Gouny, S; Donadieu, M; Guye, M; Le Fur, Y; Le Troter, A; Ranjeva, JP1
Bilaniuk, LT; De Vivo, DC; Francis, JS; Gray, SJ; Janson, CG; Leone, P; Markov, V; McCown, TJ; Samulski, RJ; Wang, DJ; Wojtas, I1
Bhatnagar, M; Surendran, S1
Erickson, RP; Totenhagen, JW; Trouard, TP; Yoshimaru, ES1
Akulov, AE; Koptug, IV; Moshkin, MP; Petrovskiĭ, DV; Petrovskiĭ, ED; Saĭk, OV; Savelov, AA1
Boeve, BF; Edland, SD; Ferman, TJ; Ivnik, RJ; Jack, CR; Kantarci, K; Knopman, DS; O'Brien, PC; Petersen, RC; Smith, GE; Tang-Wai, DF; Tangalos, EG; Weigand, SD1
Chao, L; Laxer, K; Meyerhoff, DJ; Mueller, S; Sacrey, DT; Schuff, N; Weiner, MW1
Boltshauser, E; Huisman, TA; Klein, A; Straube, T; Werner, B1
Brockmann, K; Dechent, P; Dreha-Kulaczewski, SF; Finsterbusch, J; Frahm, J; Gärtner, J; Hanefeld, FA1
Furuya, S; Imahori, Y; Mizuno, T; Nakajima, K; Nakase, T; Naruse, S; Takanashi, Y1
Abe, K; Fujita, N; Hirabuki, N; Nakamura, M; Terakawa, H; Watanabe, Y; Yanagihara, T1
Bizat, N; Bloch, G; Brouillet, E; Condé, F; Dautry, C; Hantraye, P; Henry, PG; Vaufrey, F1

Reviews

2 review(s) available for n-acetylaspartic acid and Neurodegenerative Diseases

ArticleYear
Upregulation of N-acetylaspartic acid induces oxidative stress to contribute in disease pathophysiology.
    The International journal of neuroscience, 2011, Volume: 121, Issue:6

    Topics: Animals; Antioxidants; Aspartic Acid; Brain Diseases, Metabolic; Humans; Neurodegenerative Diseases; Nitric Oxide; Oxidative Stress; Up-Regulation

2011
N-acetylaspartate as a marker of neuronal injury in neurodegenerative disease.
    Advances in experimental medicine and biology, 2006, Volume: 576

    Topics: Aging; Alcoholism; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Cocaine; Creatine; Epilepsy; Ethanol; HIV Infections; Humans; Magnetic Resonance Imaging; Neurodegenerative Diseases; Neurons; Stress Disorders, Post-Traumatic

2006

Other Studies

12 other study(ies) available for n-acetylaspartic acid and Neurodegenerative Diseases

ArticleYear
Profiles of brain oxidative damage, ventricular alterations, and neurochemical metabolites in the striatum of PINK1 knockout rats as functions of age and gender: Relevance to Parkinson disease.
    Free radical biology & medicine, 2019, 11-01, Volume: 143

    Topics: Animals; Aspartic Acid; Biomarkers; Brain; Corpus Striatum; Disease Models, Animal; Female; Gene Knockout Techniques; Glutamine; Glutathione; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Protein Kinases; Rats; Taurine

2019
Novel Homozygous Mutation of the AIMP1 Gene: A Milder Neuroimaging Phenotype With Preservation of the Deep White Matter.
    Pediatric neurology, 2019, Volume: 91

    Topics: Adolescent; Adult; Aspartic Acid; Child; Consanguinity; Cytokines; Developmental Disabilities; Epilepsy; Failure to Thrive; Female; Humans; Magnetic Resonance Imaging; Male; Microcephaly; Mutation; Neoplasm Proteins; Neurodegenerative Diseases; Pedigree; Phenotype; RNA-Binding Proteins; White Matter; Young Adult

2019
Evidencing different neurochemical profiles between thalamic nuclei using high resolution 2D-PRESS semi-LASER (1)H-MRSI at 7 T.
    Magma (New York, N.Y.), 2016, Volume: 29, Issue:3

    Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Choline; Creatine; Female; Healthy Volunteers; Humans; Lasers; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurodegenerative Diseases; Phantoms, Imaging; Phosphocreatine; Software; Spectrophotometry; Thalamus; Young Adult

2016
N-acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylase.
    Neurobiology of disease, 2016, Volume: 96

    Topics: Amidohydrolases; Animals; Aspartic Acid; Autophagy-Related Proteins; Basic Helix-Loop-Helix Transcription Factors; Brain; Canavan Disease; Child; Child, Preschool; Dependovirus; Disease Progression; Energy Metabolism; Female; Gene Expression Regulation; Green Fluorescent Proteins; HEK293 Cells; Humans; Infant; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Transgenic; Movement Disorders; Myelin Basic Protein; Myelin Sheath; Neurodegenerative Diseases; Oligodendroglia

2016
(1) H magnetic resonance spectroscopy of neurodegeneration in a mouse model of niemann-pick type C1 disease.
    Journal of magnetic resonance imaging : JMRI, 2013, Volume: 37, Issue:5

    Topics: Animals; Aspartic Acid; Biomarkers; Brain; Choline; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Mice, Transgenic; Neurodegenerative Diseases; Niemann-Pick Disease, Type C; Protons; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution

2013
[Magnetic resonance spectroscopy of metabolic changes in mice brain after 2-deoxy-D-glucose injection].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2012, Volume: 98, Issue:10

    Topics: Animals; Aspartic Acid; Brain; Choline; Deoxyglucose; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycolysis; Humans; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Male; Mice; Neurodegenerative Diseases; Radiography

2012
1H MR spectroscopy in common dementias.
    Neurology, 2004, Oct-26, Volume: 63, Issue:8

    Topics: Acetylcholine; Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Dementia; Dementia, Vascular; Diagnosis, Differential; Down-Regulation; Female; Humans; Inositol; Lewy Body Disease; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurodegenerative Diseases; Protons

2004
Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:7

    Topics: Aspartic Acid; Atrophy; Brain Diseases; Brain Edema; Cerebellum; Child; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Edema; Female; Follow-Up Studies; Humans; Infant; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neurodegenerative Diseases; Optic Atrophy; Spasms, Infantile; Syndrome

2006
Early reduction of total N-acetyl-aspartate-compounds in patients with classical vanishing white matter disease. A long-term follow-up MRS study.
    Pediatric research, 2008, Volume: 63, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Axons; Brain Diseases; Cerebrum; Child; Child, Preschool; Creatine; Female; Follow-Up Studies; Humans; Infant; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Myelin Sheath; Neurodegenerative Diseases; Phosphocreatine

2008
[A lateralized reduction of NAA in a case of corticobasal degeneration (CBD): application of proton magnetic resonance spectroscopy (1H-MRS)].
    No to shinkei = Brain and nerve, 1998, Volume: 50, Issue:5

    Topics: Aged; Aspartic Acid; Basal Ganglia Diseases; Brain; Cerebral Cortex; Cerebrovascular Circulation; Female; Functional Laterality; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neurodegenerative Diseases; Tomography, Emission-Computed

1998
Proton magnetic resonance spectroscopy (1H MRS) in patients with sporadic cerebellar degeneration.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 1999, Volume: 9, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Atrophy; Cerebellar Diseases; Cerebellum; Choline; Creatine; Disease Progression; Female; Frontal Lobe; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple System Atrophy; Neurodegenerative Diseases; Phosphocreatine; Protons; Putamen

1999
Early N-acetylaspartate depletion is a marker of neuronal dysfunction in rats and primates chronically treated with the mitochondrial toxin 3-nitropropionic acid.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:5

    Topics: Animals; Aspartic Acid; Biomarkers; Cerebral Cortex; Corpus Striatum; Dyskinesia, Drug-Induced; In Situ Nick-End Labeling; Magnetic Resonance Spectroscopy; Male; Mitochondria; Neurodegenerative Diseases; Neurons; Nitro Compounds; Papio; Propionates; Protons; Rats; Rats, Inbred Lew; Succinate Dehydrogenase

2000