n-acetylaspartic acid has been researched along with Depressive Disorder, Major in 58 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 26 (44.83) | 29.6817 |
| 2010's | 30 (51.72) | 24.3611 |
| 2020's | 2 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Allauze, E; Chabert, J; Chassain, C; De Chazeron, I; Fossati, P; Llorca, PM; Pereira, B; Rotgé, JY; Samalin, L | 1 |
| Güleş, E; Iosifescu, DV; Tural, Ü | 1 |
| Freed, RD; Gabbay, V; Hollenhorst, CN; Kang, G; Mao, X; Shungu, DC; Weiduschat, N | 1 |
| Chen, J; Jia, Y; Lai, S; Li, X; Li, Z; Lu, Q; Shan, Y; Wang, Y; Zhang, L; Zhao, H; Zhong, S | 1 |
| Blicher, AB; Blicher, JU; Knudsen, MK; Near, J; Videbech, P | 1 |
| Bansal, R; Hellerstein, DJ; O'Neill, J; Peterson, BS; Sawardekar, S | 1 |
| Álvarez, E; de Diego-Adeliño, J; Gómez-Ansón, B; López-Moruelo, O; Pérez, V; Pérez-Egea, R; Portella, MJ; Puigdemont, D; Serra-Blasco, M; Vives, Y | 1 |
| Kim, SS; Koh, SH; Lee, KU; Nam, EC; Tae, WS | 1 |
| Chen, LP; Dai, HY; Dai, ZZ; Wu, RH; Xu, CT | 1 |
| Chen, G; Cheng, K; Fan, S; Li, J; Li, W; Liu, Z; Tang, G; Xie, P; Yang, D; Yang, Y; Zhang, R; Zhou, J | 1 |
| Huang, L; Jia, Y; Ling, X; Liu, S; Wang, Y; Xiang, Q; Zhao, G; Zhong, S | 1 |
| Huang, L; Jia, Y; Liao, X; Liu, T; Wang, Y; Zhong, S | 1 |
| Bradley, KA; Case, JA; Gabbay, V; Kang, G; Mao, X; Shungu, DC | 1 |
| Ban, S; Hwang, J; Kang, HJ; Kim, JE; Kim, TS; Lyoo, IK; Namgung, E; Oh, S; Renshaw, PF; Yang, J; Yoon, S | 1 |
| Eisendrath, S; Gillung, E; Jakary, A; Li, Y; Luks, T; Mukherjee, P; Nelson, SJ | 1 |
| Bechara, A; Ding, Y; Jollant, F; Near, J; Richard-Devantoy, S; Turecki, G | 1 |
| Harris, AD; Jasaui, Y; Jaworska, N; Kirton, A; Langevin, LM; Lebel, RM; Lefebvre, D; MacMaster, FP; Sembo, M; Swansburg, R; Wilkes, TC | 1 |
| Guan, JT; Guo, XB; Li, H; Liu, CF; Ou, SM; Shen, ZW; Tan, HZ; Wang, XQ; Wen, CH; Wu, RH; Xu, CT; Zhang, J; Zhang, YN | 1 |
| Buhagiar, C; MacMaster, FP; Mirza, Y; Moore, GJ; Rosenberg, DR; Russell, A; Taormina, SP | 1 |
| Block, W; Jessen, F; Maier, W; Metten, M; Schild, H; Träber, F; von Widdern, O; Zobel, A | 1 |
| Krishnan, RR; Song, AW; Steffens, DC; Taylor, WD; Venkatraman, TN | 1 |
| Chen, CS; Chiang, IC; Hsieh, TJ; Kuo, YT; Li, CW; Lin, HF; Lin, WC; Liu, GC; Lu, CY | 1 |
| Hall, GB; MacQueen, GM; Milne, A; Soreni, N; Yucel, K | 1 |
| Stein, MB | 1 |
| Beck, J; Boeker, H; Boesiger, P; Dydak, U; Grimm, S; Henning, A; Northoff, G; Schnepf, B; Schulte, RF; Walter, M | 1 |
| Demir, B; Kaymak, SU; Oğuz, KK; Sentürk, S; Uluğ, B | 1 |
| Caetano, SC; Chen, HH; Hatch, JP; Matsuo, K; Monkul, ES; Najt, P; Nery, FG; Nicoletti, MA; Peluso, MA; Soares, JC; Stanley, JA | 1 |
| Barker, PB; Bertrand, M; Degoankar, M; Horská, A; Munro, CA; Pham, D; Rao, V; Rosenberg, P; Ward, J; Yousem, DM | 1 |
| Chang, HC; Chen, CS; Ko, CH; Kuo, YT; Li, CW; Lin, HF; Liu, GC; Yeh, YC; Yen, CF | 1 |
| Reynolds, GP; Reynolds, LM | 1 |
| Caetano, SC; Chen, HH; Fonseca, M; Hatch, JP; Nicoletti, M; Olvera, RL; Pliszka, SR; Soares, JC; Stanley, JA | 1 |
| de Diego-Adeliño, J; Gómez-Ansón, B; Morgan-Ferrando, R; Pérez, V; Pérez-Egea, R; Portella, MJ; Puigdemont, D; Ruscalleda, J; Vives, Y | 1 |
| Bajbouj, M; Brakemeier, EL; Grimm, S; Heuser, I; Luborzewski, A; Merkl, A; Quante, A; Schubert, F | 1 |
| Alexander, M; Becker, A; Bettecken, T; Binder, EB; Bradley, B; Breen, G; Cichon, S; Craig, IW; Czamara, D; Czisch, M; Demirkan, A; Heck, A; Hek, K; Hennings, J; Hoehn, D; Hofman, A; Holsboer, F; Ising, M; Kohli, MA; Lewis, CM; Lucae, S; Maier, W; Menke, A; Müller, MB; Müller-Myhsok, B; Nöthen, MM; Ressler, KJ; Rietschel, M; Ripke, S; Saemann, PG; Salyakina, D; Schmidt, MV; Schramm, J; Schreiber, S; Specht, M; Tiemeier, H; Uhr, M; van Duijn, CM; Wolf, C | 1 |
| Huang, L; Jia, Y; Ling, X; Liu, S; Wang, Y; Xu, G | 1 |
| Czisch, M; Holsboer, F; Kaltwasser, SF; Knapman, A; Landgraf, R; Martins-de-Souza, D; Touma, C; Turck, CW | 1 |
| Cowen, PJ; Godlewska, BR; Near, J; Norbury, R; Selvaraj, S; Taylor, MJ | 1 |
| Alger, JR; Espinoza, RT; Narr, KL; Phillips, OR; Woods, RP; Zhang, J | 1 |
| Chen, X; Huang, L; Jia, Y; Ling, X; Liu, S; Wang, Y; Xu, G | 1 |
| Cookson, MR; Drevets, WC; Gibbs, JR; Goldman, D; Hasler, G; Hodgkinson, C; Neumeister, A; Preuss, N; Salehi, B; Shen, J; Singleton, A; van der Veen, JW; Wendland, JR | 1 |
| Berk, M; Das, P; Dean, OM; Dodd, S; Fritz, K; Malhi, GS; Tanious, M | 1 |
| Arolt, V; Erfurth, A; Heindel, W; Michael, N; Ohrmann, P; Pfleiderer, B | 1 |
| Braus, DF; Ende, G; Henn, FA; Obergriesser, T | 1 |
| Blitchington, T; Charles, HC; Kelly, L; Krishnan, KR; Tupler, LA; Vythilingam, M | 1 |
| Berger, G; Desmond, P; McGorry, PD; Pantelis, C; Phillips, LJ; Velakoulis, D; Wood, SJ; Yung, AR | 1 |
| Altamura, M; Antonucci, N; Bertolino, A; Blasi, G; Brudaglio, F; Nardini, M; Scarabino, T; Sciota, D; Weinberger, DR | 1 |
| Banerjee, SP; Bhandari, R; Boyd, C; Ivey, J; Mirza, Y; Moore, GJ; Rose, M; Rosenberg, DR; Russell, A; Smith, JM; Tang, J | 1 |
| Allen, PS; Coupland, NJ; Hanstock, CC; Hegadoren, KM; Ogilvie, CJ; Seres, P | 1 |
| Ankerst, DP; Yildiz-Yesiloglu, A | 1 |
| Demirakca, T; Ende, G; Henn, FA; Sartorius, A; Walter, S; Wildgruber, D; Wokrina, T | 1 |
| Ajilore, O; Binesh, N; Darwin, C; Haroon, E; Kumar, A; Kumaran, S; Miller, J; Mintz, J; Thomas, MA | 1 |
| Baro, P; Bougerol, T; Holtzmann, J; Polosan, M | 1 |
| Babb, JS; Gabbay, V; Gonen, O; Hess, DA; Klein, RG; Liu, S | 1 |
| Fox-Bosetti, S; Kornak, J; Lenoci, M; Marmar, CR; Neylan, TC; Samuelson, KW; Schuff, N; Studholme, C; Weiner, MW | 1 |
| Iidaka, T; Itoh, H; Kado, H; Kimura, H; Kosaka, H; Murata, T; Omori, M; Wada, Y | 1 |
| Gates, L; Khan, SC; Kusumakar, V; MacMaster, FP; Sparkes, SJ | 1 |
| Curran, J; Estanol, L; Huda, A; Kumar, A; Lavretsky, H; Mega, M; Mintz, J; Thomas, A; Toga, A; Venkatraman, T; Yue, K | 1 |
| Grachev, ID; Ramachandran, TS; Thomas, PS | 1 |
4 review(s) available for n-acetylaspartic acid and Depressive Disorder, Major
| Article | Year |
|---|---|
Glutamatergic and N-Acetylaspartate Metabolites in Bipolar Disorder: A Systematic Review and Meta-Analysis of Proton Magnetic Resonance Spectroscopy Studies.
Topics: Aspartic Acid; Bipolar Disorder; Depressive Disorder, Major; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy | 2022 |
Neurobiology of generalized anxiety disorder.
Topics: Anxiety Disorders; Aspartic Acid; Brain; Cognition; Comorbidity; Creatine; Depressive Disorder, Major; Diagnosis, Differential; Genetic Linkage; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neurobiology; Risk Factors; Twin Studies as Topic | 2009 |
Review of 1H magnetic resonance spectroscopy findings in major depressive disorder: a meta-analysis.
Topics: Aspartic Acid; Brain; Choline; Creatine; Depressive Disorder, Major; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Inositol; Magnetic Resonance Spectroscopy; Phosphocreatine; Protons | 2006 |
[ECT: from neuronal plasticity to mechanisms underlying antidepressant medication effect].
Topics: Antidepressive Agents; Aspartic Acid; Brain; Brain-Derived Neurotrophic Factor; Choline; Depressive Disorder, Major; Electroconvulsive Therapy; Exons; Humans; Neuronal Plasticity | 2007 |
7 trial(s) available for n-acetylaspartic acid and Depressive Disorder, Major
| Article | Year |
|---|---|
Effects of the antidepressant medication duloxetine on brain metabolites in persistent depressive disorder: A randomized, controlled trial.
Topics: Adult; Antidepressive Agents; Aspartic Acid; Brain; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Treatment Outcome | 2019 |
Anterior cingulate cortex and cerebellar hemisphere neurometabolite changes in depression treatment: A 1H magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Antidepressive Agents; Aspartic Acid; Cerebellum; Choline; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Male; Middle Aged; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Young Adult | 2014 |
Effects of Creatine Monohydrate Augmentation on Brain Metabolic and Network Outcome Measures in Women With Major Depressive Disorder.
Topics: Adult; Aged; Aspartic Acid; Brain; Case-Control Studies; Citalopram; Creatine; Depressive Disorder, Major; Diffusion Tensor Imaging; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Middle Aged; Neural Pathways; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Young Adult | 2016 |
Early increase in marker of neuronal integrity with antidepressant treatment of major depression: 1H-magnetic resonance spectroscopy of N-acetyl-aspartate.
Topics: Adolescent; Adult; Antidepressive Agents; Aspartic Acid; Biomarkers; Citalopram; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Protons; Time Factors; Treatment Outcome; Young Adult | 2012 |
Glutamate normalization with ECT treatment response in major depression.
Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Glutamic Acid; Gyrus Cinguli; Humans; Male | 2013 |
Hippocampal N-acetylaspartate and morning cortisol levels in drug-naive, first-episode patients with major depressive disorder: effects of treatment.
Topics: Adolescent; Adult; Antidepressive Agents; Aspartic Acid; Case-Control Studies; Choline; Creatine; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Hippocampus; Humans; Hydrocortisone; Magnetic Resonance Spectroscopy; Male; Middle Aged; Thiophenes; Young Adult | 2012 |
Metabolite profiles in the anterior cingulate cortex of depressed patients differentiate those taking N-acetyl-cysteine versus placebo.
Topics: Acetylcysteine; Aspartic Acid; Depressive Disorder, Major; Double-Blind Method; Female; Free Radical Scavengers; Functional Neuroimaging; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Male; Middle Aged; Oxidative Stress | 2013 |
47 other study(ies) available for n-acetylaspartic acid and Depressive Disorder, Major
| Article | Year |
|---|---|
Plasma Neuronal and Glial Markers and Anterior Cingulate Metabolite Levels in Major Depressive Disorder: A Pilot Study.
Topics: Adult; Aspartic Acid; Choline; Creatine; Depressive Disorder, Major; Female; Gyrus Cinguli; Humans; Male; Middle Aged; Phosphopyruvate Hydratase; Pilot Projects; Proton Magnetic Resonance Spectroscopy; S100 Calcium Binding Protein beta Subunit | 2020 |
A pilot study of cortical glutathione in youth with depression.
Topics: Adolescent; Anhedonia; Aspartic Acid; Case-Control Studies; Child; Choline; Creatine; Depression; Depressive Disorder, Major; Female; Glutathione; Humans; Male; Occipital Lobe; Oxidative Stress; Pilot Projects; Proton Magnetic Resonance Spectroscopy; Young Adult | 2017 |
Correlations between working memory impairment and neurometabolites of prefrontal cortex and lenticular nucleus in patients with major depressive disorder.
Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Corpus Striatum; Creatine; Depressive Disorder, Major; Female; Humans; Inositol; Male; Memory Disorders; Memory, Short-Term; Neuropsychological Tests; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy | 2018 |
Magnetic resonance (MR) spectroscopic measurement of γ-aminobutyric acid (GABA) in major depression before and after electroconvulsive therapy.
Topics: Adult; Aspartic Acid; Depressive Disorder, Major; Electroconvulsive Therapy; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Prefrontal Cortex; Treatment Outcome; Young Adult | 2019 |
Hippocampal abnormalities of glutamate/glutamine, N-acetylaspartate and choline in patients with depression are related to past illness burden.
Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Cost of Illness; Cross-Sectional Studies; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged | 2013 |
Progressive decrease of N-acetylaspartate to total creatine ratio in the pregenual anterior cingulate cortex in patients with major depressive disorder: longitudinal 1H-MR spectroscopy study.
Topics: Adult; Antidepressive Agents; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cross-Sectional Studies; Depressive Disorder, Major; Female; Gyrus Cinguli; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Phosphocreatine | 2014 |
Amino acid metabolic dysfunction revealed in the prefrontal cortex of a rat model of depression.
Topics: Amino Acids; Animals; Aspartic Acid; Behavior, Animal; beta-Alanine; Depressive Disorder, Major; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glycerol; Isoleucine; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2015 |
Similarities of biochemical abnormalities between major depressive disorder and bipolar depression: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain; Choline; Creatine; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Young Adult | 2014 |
The correlation between biochemical abnormalities in frontal white matter, hippocampus and serum thyroid hormone levels in first-episode patients with major depressive disorder.
Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Depressive Disorder, Major; Female; Hippocampus; Humans; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Thyroid Hormones; Thyrotropin; White Matter | 2015 |
Increased ventricular cerebrospinal fluid lactate in depressed adolescents.
Topics: Adolescent; Aspartic Acid; Cerebral Ventricles; Cerebrospinal Fluid; Choline; Creatine; Depressive Disorder, Major; Female; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mitochondria; Statistics as Topic; Young Adult | 2016 |
Evaluating metabolites in patients with major depressive disorder who received mindfulness-based cognitive therapy and healthy controls using short echo MRSI at 7 Tesla.
Topics: Adult; Aspartic Acid; Case-Control Studies; Caudate Nucleus; Cerebral Cortex; Cognitive Behavioral Therapy; Depressive Disorder, Major; Female; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Mindfulness; Putamen; Thalamus; Treatment Outcome; Young Adult | 2016 |
Prefrontal inositol levels and implicit decision-making in healthy individuals and depressed patients.
Topics: Adult; Aspartic Acid; Decision Making; Delay Discounting; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Inositol; Learning; Magnetic Resonance Imaging; Male; Middle Aged; Nervous System Physiological Phenomena; Neuroimaging; Neurons; Neuropsychological Tests; Prefrontal Cortex; Reproducibility of Results; Task Performance and Analysis | 2016 |
A pilot study of hippocampal N-acetyl-aspartate in youth with treatment resistant major depression.
Topics: Adolescent; Aspartic Acid; Brain; Case-Control Studies; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Female; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Pilot Projects; Proton Magnetic Resonance Spectroscopy; Young Adult | 2017 |
Main Effects of Diagnoses, Brain Regions, and their Interaction Effects for Cerebral Metabolites in Bipolar and Unipolar Depressive Disorders.
Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Depressive Disorder, Major; Glutamine; Gray Matter; Humans; Inositol; Organ Specificity | 2016 |
Medial temporal N-acetyl-aspartate in pediatric major depression.
Topics: Adolescent; Aspartic Acid; Child; Choline; Creatine; Depressive Disorder, Major; Female; Humans; Male | 2008 |
Proton MR spectroscopy of the hippocampus at 3 T in patients with unipolar major depressive disorder: correlates and predictors of treatment response.
Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Statistics, Nonparametric; Young Adult | 2009 |
Biochemical abnormalities of the medial temporal lobe and medial prefrontal cortex in late-life depression.
Topics: Aspartic Acid; Choline; Creatine; Depressive Disorder, Major; Energy Metabolism; Functional Laterality; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Prefrontal Cortex; Temporal Lobe; Whole Body Imaging | 2009 |
Proton magnetic resonance spectroscopy of late-life major depressive disorder.
Topics: Aged; Aging; Aspartic Acid; Basal Ganglia; Biomarkers; Brain; Choline; Cognition; Creatine; Depressive Disorder, Major; Dominance, Cerebral; Female; Frontal Lobe; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Psychiatric Status Rating Scales | 2009 |
Hippocampal metabolic abnormalities at first onset and with recurrent episodes of a major depressive disorder: a proton magnetic resonance spectroscopy study.
Topics: Adult; Analysis of Variance; Aspartic Acid; Choline; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Organ Size; Protons; Recurrence | 2009 |
The relationship between aberrant neuronal activation in the pregenual anterior cingulate, altered glutamatergic metabolism, and anhedonia in major depression.
Topics: Adult; Arousal; Aspartic Acid; Blood Glucose; Corpus Callosum; Depressive Disorder, Major; Dominance, Cerebral; Emotions; Energy Metabolism; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Oxygen Consumption; Synaptic Transmission | 2009 |
Antidepressant effect detected on proton magnetic resonance spectroscopy in drug-naïve female patients with first-episode major depression.
Topics: Adult; Antidepressive Agents; Aspartic Acid; Case-Control Studies; Choline; Creatine; Depressive Disorder, Major; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Middle Aged; Prefrontal Cortex; Protons | 2009 |
Normal metabolite levels in the left dorsolateral prefrontal cortex of unmedicated major depressive disorder patients: a single voxel (1)H spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Brain Mapping; Case-Control Studies; Chi-Square Distribution; Creatine; Depressive Disorder, Major; Female; Functional Laterality; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Prefrontal Cortex; Protons; Psychiatric Status Rating Scales; Young Adult | 2009 |
Neuroanatomical correlates of depression in post traumatic brain injury: preliminary results of a pilot study.
Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Brain Injuries; Case-Control Studies; Choline; Cognition Disorders; Creatine; Depressive Disorder, Major; Frontal Lobe; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Middle Aged; Neuropsychological Tests; Organ Size; Pilot Projects; Time Factors | 2010 |
Brain proton magnetic resonance spectroscopic study of insight among elders with late-life depression in remission.
Topics: Aged; Aspartic Acid; Awareness; Choline; Creatine; Depressive Disorder, Major; Dominance, Cerebral; Energy Metabolism; Female; Frontal Lobe; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Patient Acceptance of Health Care; Somatoform Disorders; Taiwan | 2010 |
Differential regional N-acetylaspartate deficits in postmortem brain in schizophrenia, bipolar disorder and major depressive disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Depressive Disorder, Major; Dipeptides; Female; Humans; Male; Middle Aged; Schizophrenia | 2011 |
Reduced medial prefrontal N-acetyl-aspartate levels in pediatric major depressive disorder: a multi-voxel in vivo(1)H spectroscopy study.
Topics: Adolescent; Affect; Aspartic Acid; Brain Mapping; Child; Creatine; Depressive Disorder, Major; Female; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Phosphorylcholine; Prefrontal Cortex | 2010 |
Ventromedial prefrontal spectroscopic abnormalities over the course of depression: a comparison among first episode, remitted recurrent and chronic patients.
Topics: Adult; Age of Onset; Aspartic Acid; Choline; Chronic Disease; Depressive Disorder, Major; Disease Progression; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multivariate Analysis; Prefrontal Cortex | 2011 |
Abnormal cingulate and prefrontal cortical neurochemistry in major depression after electroconvulsive therapy.
Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Mental Recall; Middle Aged; Neuropsychological Tests; Phosphocreatine; Prefrontal Cortex; Severity of Illness Index; Treatment Outcome; Verbal Learning | 2011 |
The neuronal transporter gene SLC6A15 confers risk to major depression.
Topics: Adult; Amino Acid Transport Systems, Neutral; Analysis of Variance; Animals; Aspartic Acid; Chromosomes, Human, Pair 12; Depressive Disorder, Major; Disease Models, Animal; Female; Gene Expression Regulation; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Germany; Hippocampus; Humans; Linkage Disequilibrium; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Meta-Analysis as Topic; Mice; Middle Aged; Nerve Tissue Proteins; Polymorphism, Single Nucleotide; Risk Factors; RNA, Messenger; Stress, Psychological; Tritium; United Kingdom | 2011 |
Frontal white matter biochemical abnormalities in first-episode, treatment-naive patients with major depressive disorder: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Brain Diseases; Choline; Creatine; Depressive Disorder, Major; Female; Frontal Lobe; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Young Adult | 2012 |
Increased stress reactivity is associated with reduced hippocampal activity and neuronal integrity along with changes in energy metabolism.
Topics: Animals; Aspartic Acid; Behavior, Animal; Cognition Disorders; Depressive Disorder, Major; Disease Models, Animal; Energy Metabolism; Hippocampus; Humans; Hypothalamo-Hypophyseal System; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred Strains; Neurons; Pituitary-Adrenal System; Proteome; Stress, Psychological | 2012 |
Age-modulated association between prefrontal NAA and the BDNF gene.
Topics: Adolescent; Adult; Aging; Aspartic Acid; Brain-Derived Neurotrophic Factor; Depression; Depressive Disorder, Major; Female; Genetic Association Studies; Genotype; Humans; Linear Models; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Polymorphism, Single Nucleotide; Prefrontal Cortex; RNA, Messenger; Young Adult | 2013 |
Neurotrophic effects of electroconvulsive therapy: a proton magnetic resonance study of the left amygdalar region in patients with treatment-resistant depression.
Topics: Adult; Aged; Amygdala; Aspartic Acid; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Growth Factors; Protons; Statistics, Nonparametric | 2003 |
Long-term follow-up of magnetic resonance-detectable choline signal changes in the hippocampus of patients treated with electroconvulsive therapy.
Topics: Aspartic Acid; Choline; Cognition Disorders; Creatine; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Follow-Up Studies; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Phosphocreatine; Recurrence; Severity of Illness Index; Signal Transduction; Time Factors | 2003 |
Focal and lateralized subcortical abnormalities in unipolar major depressive disorder: an automated multivoxel proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Brain Mapping; Choline; Creatine; Depressive Disorder, Major; Female; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Psychiatric Status Rating Scales; Radionuclide Imaging | 2003 |
Proton magnetic resonance spectroscopy in first episode psychosis and ultra high-risk individuals.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain Mapping; Choline; Creatine; Depressive Disorder, Major; Dominance, Cerebral; Energy Metabolism; Female; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Net; Prefrontal Cortex; Psychotic Disorders; Reference Values; Risk; Schizophrenia; Schizotypal Personality Disorder; Temporal Lobe | 2003 |
Hippocampal neurochemical pathology in patients at first episode of affective psychosis: a proton magnetic resonance spectroscopic imaging study.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Cerebral Cortex; Choline; Creatine; Depressive Disorder, Major; Dominance, Cerebral; Female; Gyrus Cinguli; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurons; Phosphocreatine; Psychiatric Status Rating Scales; Putamen; Reference Values; Thalamus | 2004 |
Reduced anterior cingulate glutamatergic concentrations in childhood OCD and major depression versus healthy controls.
Topics: Adolescent; Aspartic Acid; Child; Choline; Creatine; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Obsessive-Compulsive Disorder; Personality Assessment; Phosphocreatine; Reference Values; Synaptic Transmission | 2004 |
Decreased prefrontal Myo-inositol in major depressive disorder.
Topics: Adult; Aspartic Acid; Brain Chemistry; Brain Mapping; Case-Control Studies; Choline; Creatine; Depressive Disorder, Major; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex | 2005 |
Subcortical and medial temporal MR-detectable metabolite abnormalities in unipolar major depression.
Topics: Adult; Aspartic Acid; Brain Chemistry; Cell Membrane; Cerebral Cortex; Creatine; Depressive Disorder, Major; Energy Metabolism; Female; Humans; Magnetic Resonance Imaging; Male; Myelin Sheath; Phosphocreatine; Psychiatric Status Rating Scales; Putamen; Temporal Lobe | 2007 |
Measurement of brain metabolites in patients with type 2 diabetes and major depression using proton magnetic resonance spectroscopy.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Chemistry; Choline; Creatine; Depressive Disorder, Major; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Psychiatric Status Rating Scales | 2007 |
Lateralized caudate metabolic abnormalities in adolescent major depressive disorder: a proton MR spectroscopy study.
Topics: Adolescent; Aspartic Acid; Caudate Nucleus; Choline; Cohort Studies; Creatine; Depressive Disorder, Major; Female; Functional Laterality; Humans; Imaging, Three-Dimensional; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Psychology, Adolescent; Putamen; Severity of Illness Index; Thalamus | 2007 |
Abnormal N-acetylaspartate in hippocampus and anterior cingulate in posttraumatic stress disorder.
Topics: Adult; Alcoholism; Algorithms; Aspartic Acid; Atrophy; Combat Disorders; Comorbidity; Conditioning, Classical; Creatine; Depressive Disorder, Major; Dominance, Cerebral; Energy Metabolism; Extinction, Psychological; Fear; Female; Frontal Lobe; Gyrus Cinguli; Hippocampus; Humans; Image Processing, Computer-Assisted; Life Change Events; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Software; Stress Disorders, Post-Traumatic; Veterans | 2008 |
MRI white matter hyperintensities, (1)H-MR spectroscopy and cognitive function in geriatric depression: a comparison of early- and late-onset cases.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Choline; Creatine; Depressive Disorder, Major; Energy Metabolism; Female; Frontal Lobe; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Degeneration; Neuropsychological Tests; Reference Values | 2001 |
Left medial temporal cytosolic choline in early onset depression.
Topics: Adolescent; Amygdala; Aspartic Acid; Choline; Creatine; Cytosol; Depressive Disorder, Major; Dominance, Cerebral; Female; Humans; Magnetic Resonance Spectroscopy; Male; Personality Inventory; Reference Values | 2001 |
Frontal white matter biochemical abnormalities in late-life major depression detected with proton magnetic resonance spectroscopy.
Topics: Aged; Aspartic Acid; Choline; Creatine; Depressive Disorder, Major; Dominance, Cerebral; Energy Metabolism; Female; Frontal Lobe; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Psychiatric Status Rating Scales; Reference Values | 2002 |
Decreased levels of N-acetylaspartate in dorsolateral prefrontal cortex in a case of intractable severe sympathetically mediated chronic pain (complex regional pain syndrome, type I).
Topics: Adult; Anxiety Disorders; Aspartic Acid; Chronic Disease; Depressive Disorder, Major; Female; Humans; Magnetic Resonance Imaging; Pain; Pain Measurement; Prefrontal Cortex | 2002 |