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n-acetylaspartic acid and Degenerative Diseases, Central Nervous System

n-acetylaspartic acid has been researched along with Degenerative Diseases, Central Nervous System in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's5 (35.71)29.6817
2010's7 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Butterfield, DA; Hinchie, A; Powell, DK; Ren, X; Swomley, A1
AlHashem, A; AlShahwan, S; BoAli, A; Tabarki, B; Tlili-Graiess, K; Zuccoli, G1
Confort-Gouny, S; Donadieu, M; Guye, M; Le Fur, Y; Le Troter, A; Ranjeva, JP1
Bilaniuk, LT; De Vivo, DC; Francis, JS; Gray, SJ; Janson, CG; Leone, P; Markov, V; McCown, TJ; Samulski, RJ; Wang, DJ; Wojtas, I1
Bhatnagar, M; Surendran, S1
Erickson, RP; Totenhagen, JW; Trouard, TP; Yoshimaru, ES1
Akulov, AE; Koptug, IV; Moshkin, MP; Petrovskiĭ, DV; Petrovskiĭ, ED; Saĭk, OV; Savelov, AA1
Boeve, BF; Edland, SD; Ferman, TJ; Ivnik, RJ; Jack, CR; Kantarci, K; Knopman, DS; O'Brien, PC; Petersen, RC; Smith, GE; Tang-Wai, DF; Tangalos, EG; Weigand, SD1
Chao, L; Laxer, K; Meyerhoff, DJ; Mueller, S; Sacrey, DT; Schuff, N; Weiner, MW1
Boltshauser, E; Huisman, TA; Klein, A; Straube, T; Werner, B1
Brockmann, K; Dechent, P; Dreha-Kulaczewski, SF; Finsterbusch, J; Frahm, J; Gärtner, J; Hanefeld, FA1
Furuya, S; Imahori, Y; Mizuno, T; Nakajima, K; Nakase, T; Naruse, S; Takanashi, Y1
Abe, K; Fujita, N; Hirabuki, N; Nakamura, M; Terakawa, H; Watanabe, Y; Yanagihara, T1
Bizat, N; Bloch, G; Brouillet, E; Condé, F; Dautry, C; Hantraye, P; Henry, PG; Vaufrey, F1

Reviews

2 review(s) available for n-acetylaspartic acid and Degenerative Diseases, Central Nervous System

ArticleYear
Upregulation of N-acetylaspartic acid induces oxidative stress to contribute in disease pathophysiology.
    The International journal of neuroscience, 2011, Volume: 121, Issue:6

    Topics: Animals; Antioxidants; Aspartic Acid; Brain Diseases, Metabolic; Humans; Neurodegenerative Diseases; Nitric Oxide; Oxidative Stress; Up-Regulation

2011
N-acetylaspartate as a marker of neuronal injury in neurodegenerative disease.
    Advances in experimental medicine and biology, 2006, Volume: 576

    Topics: Aging; Alcoholism; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Cocaine; Creatine; Epilepsy; Ethanol; HIV Infections; Humans; Magnetic Resonance Imaging; Neurodegenerative Diseases; Neurons; Stress Disorders, Post-Traumatic

2006

Other Studies

12 other study(ies) available for n-acetylaspartic acid and Degenerative Diseases, Central Nervous System

ArticleYear
Profiles of brain oxidative damage, ventricular alterations, and neurochemical metabolites in the striatum of PINK1 knockout rats as functions of age and gender: Relevance to Parkinson disease.
    Free radical biology & medicine, 2019, 11-01, Volume: 143

    Topics: Animals; Aspartic Acid; Biomarkers; Brain; Corpus Striatum; Disease Models, Animal; Female; Gene Knockout Techniques; Glutamine; Glutathione; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Protein Kinases; Rats; Taurine

2019
Novel Homozygous Mutation of the AIMP1 Gene: A Milder Neuroimaging Phenotype With Preservation of the Deep White Matter.
    Pediatric neurology, 2019, Volume: 91

    Topics: Adolescent; Adult; Aspartic Acid; Child; Consanguinity; Cytokines; Developmental Disabilities; Epilepsy; Failure to Thrive; Female; Humans; Magnetic Resonance Imaging; Male; Microcephaly; Mutation; Neoplasm Proteins; Neurodegenerative Diseases; Pedigree; Phenotype; RNA-Binding Proteins; White Matter; Young Adult

2019
Evidencing different neurochemical profiles between thalamic nuclei using high resolution 2D-PRESS semi-LASER (1)H-MRSI at 7 T.
    Magma (New York, N.Y.), 2016, Volume: 29, Issue:3

    Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Choline; Creatine; Female; Healthy Volunteers; Humans; Lasers; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurodegenerative Diseases; Phantoms, Imaging; Phosphocreatine; Software; Spectrophotometry; Thalamus; Young Adult

2016
N-acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylase.
    Neurobiology of disease, 2016, Volume: 96

    Topics: Amidohydrolases; Animals; Aspartic Acid; Autophagy-Related Proteins; Basic Helix-Loop-Helix Transcription Factors; Brain; Canavan Disease; Child; Child, Preschool; Dependovirus; Disease Progression; Energy Metabolism; Female; Gene Expression Regulation; Green Fluorescent Proteins; HEK293 Cells; Humans; Infant; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Transgenic; Movement Disorders; Myelin Basic Protein; Myelin Sheath; Neurodegenerative Diseases; Oligodendroglia

2016
(1) H magnetic resonance spectroscopy of neurodegeneration in a mouse model of niemann-pick type C1 disease.
    Journal of magnetic resonance imaging : JMRI, 2013, Volume: 37, Issue:5

    Topics: Animals; Aspartic Acid; Biomarkers; Brain; Choline; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Mice, Transgenic; Neurodegenerative Diseases; Niemann-Pick Disease, Type C; Protons; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution

2013
[Magnetic resonance spectroscopy of metabolic changes in mice brain after 2-deoxy-D-glucose injection].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2012, Volume: 98, Issue:10

    Topics: Animals; Aspartic Acid; Brain; Choline; Deoxyglucose; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycolysis; Humans; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Male; Mice; Neurodegenerative Diseases; Radiography

2012
1H MR spectroscopy in common dementias.
    Neurology, 2004, Oct-26, Volume: 63, Issue:8

    Topics: Acetylcholine; Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Dementia; Dementia, Vascular; Diagnosis, Differential; Down-Regulation; Female; Humans; Inositol; Lewy Body Disease; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurodegenerative Diseases; Protons

2004
Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:7

    Topics: Aspartic Acid; Atrophy; Brain Diseases; Brain Edema; Cerebellum; Child; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Edema; Female; Follow-Up Studies; Humans; Infant; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neurodegenerative Diseases; Optic Atrophy; Spasms, Infantile; Syndrome

2006
Early reduction of total N-acetyl-aspartate-compounds in patients with classical vanishing white matter disease. A long-term follow-up MRS study.
    Pediatric research, 2008, Volume: 63, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Axons; Brain Diseases; Cerebrum; Child; Child, Preschool; Creatine; Female; Follow-Up Studies; Humans; Infant; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Myelin Sheath; Neurodegenerative Diseases; Phosphocreatine

2008
[A lateralized reduction of NAA in a case of corticobasal degeneration (CBD): application of proton magnetic resonance spectroscopy (1H-MRS)].
    No to shinkei = Brain and nerve, 1998, Volume: 50, Issue:5

    Topics: Aged; Aspartic Acid; Basal Ganglia Diseases; Brain; Cerebral Cortex; Cerebrovascular Circulation; Female; Functional Laterality; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neurodegenerative Diseases; Tomography, Emission-Computed

1998
Proton magnetic resonance spectroscopy (1H MRS) in patients with sporadic cerebellar degeneration.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 1999, Volume: 9, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Atrophy; Cerebellar Diseases; Cerebellum; Choline; Creatine; Disease Progression; Female; Frontal Lobe; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple System Atrophy; Neurodegenerative Diseases; Phosphocreatine; Protons; Putamen

1999
Early N-acetylaspartate depletion is a marker of neuronal dysfunction in rats and primates chronically treated with the mitochondrial toxin 3-nitropropionic acid.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:5

    Topics: Animals; Aspartic Acid; Biomarkers; Cerebral Cortex; Corpus Striatum; Dyskinesia, Drug-Induced; In Situ Nick-End Labeling; Magnetic Resonance Spectroscopy; Male; Mitochondria; Neurodegenerative Diseases; Neurons; Nitro Compounds; Papio; Propionates; Protons; Rats; Rats, Inbred Lew; Succinate Dehydrogenase

2000