Page last updated: 2024-08-24

n-acetylaspartic acid and Cognitive Dysfunction

n-acetylaspartic acid has been researched along with Cognitive Dysfunction in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's29 (82.86)24.3611
2020's6 (17.14)2.80

Authors

AuthorsStudies
Cordato, DJ; Shad, KF; Soubra, W1
Chitty, K; Haber, PS; Lagopoulos, J; Logge, W; Morley, KC; Moustafa, AA1
Hong, Q; Li, S; Lian, X; Yin, C; Zhao, W1
Atiya, S; Bartha, R; Borrie, MJ; Brymer, C; Fogarty, J; Montero-Odasso, M; Pasternak, SH; Wong, D1
Balcioglu, YH; Sen, M; Yesilkaya, UH1
Briemberg, H; Eurich, DT; Frayne, R; Genge, AL; Graham, SJ; Hanstock, C; Ishaque, A; Kalra, S; Korngut, L; Luk, C; Seres, P; Srivastava, O; Ta, D; Zinman, L1
Chen, W; Gong, ZK; Sheng, C; Wang, M; Wang, SY; Wang, XX1
Moriya, M; Nojo, T; Waragai, M1
Denney, TS; Gawne, TJ; Lahti, AC; Reid, MA; Salibi, N; White, DM1
Aslan, S; Chen, JR; Choi, C; Khan, DA; Kroll, JL; Patel, SV; Pinkham, AE; Ritz, T; Sherwood Brown, E; Steele, AM1
Alakkas, A; Clifford, DB; Collier, A; Ellis, RJ; Fennema-Notestine, C; Gelman, B; Gianella, S; Grant, I; Heaton, RK; Kallianpur, A; Letendre, S; Marcotte, T; Marra, C; McCutchan, JA; Morgello, S; Sacktor, N; Simpson, D; Umlauf, A; Watson, CW1
Cai, ZL; Liu, Y; Wu, F; Xue, S; Zhou, X1
Kantarci, K1
Andrade-Valença, LP; Menezes, TL; Valença, MM1
Aleman, A; Martens, S; Tumati, S1
Alvarez-Linera, J; Frank, A; García-Álvarez, R; Hernández-Tamames, JA; Loureiro, JP; Mato Abad, V; Quirós, A1
Sukying, C; Suriyajakryuththana, W; Teepprasarn, N; Tuntiyatorn, L1
Amann, M; Babb, JS; Gass, A; Glodzik, L; Gokhale, A; Gonen, O; Hirsch, JG; Monsch, AU; Rusinek, H; Sollberger, M1
Akiguchi, I; Shiino, A; Watanabe, T1
Almuqbel, M; Anderson, TJ; Dalrymple-Alford, JC; Keenan, RJ; Livingston, L; MacAskill, MR; Melzer, TR; Myall, DJ; Pitcher, TL; Wood, KL1
Anderson, PJ; Bainbridge, A; Burnett, AC; Cheong, JL; Doyle, LW; Lee, KJ; Roberts, G; Robertson, NJ; Thompson, DK; Wood, SJ1
Meng, N; Shi, S; Su, Y1
Chen, W; Chen, X; Guo, Z; Hou, H; Liu, X; Shen, Y; Wei, F1
Hwang, J; Jeon, S; Kang, I; Kim, B; Kim, GH; Kim, JE; Kim, JY; Lyoo, IK; Ma, J; Renshaw, PF; Yoon, S; Yurgelun-Todd, DA1
Bulik, M; Burkon, P; Dobiaskova, M; Hynkova, L; Jancalek, R; Kazda, T; Laack, NN; Pospisil, P; Slampa, P1
Daly, EM; Foy, CM; Glover, A; Lovestone, S; Murphy, DG; O'Gorman, R; Simmons, A1
Chen, K; Ding, B; Fang, Y; Li, X; Ling, H; Wang, T; Xiao, S1
Arlt, S; Block, W; Ende, G; Frölich, L; Gür, O; Hammen, T; Jessen, F; Kornhuber, J; Kucinski, T; Lewczuk, P; Maier, W; Peters, O; Popp, J; Träber, F; Wiltfang, J1
Aguilar, K; Fayed, N; Modrego, PJ; Rojas-Salinas, G1
Barcikowska, M; Ćwikła, JB; Gabryelewicz, T; Walecki, J1
Andreiuolo, PA; Bottino, CM; de Oliveira-Souza, R; Moll, J; Silveira de Souza, A; Tovar-Moll, F1
Fayed, N; Modrego, PJ1
Choi, JY; Hong, YH; Kim, HS; Lim, TS; Moon, SY1
Delfino, M; García-Sánchez, C; Gironell, A; Gómez-Ansón, B; Kulisevsky, J; Llebaria, G; Pagonabarraga, J; Pascual-Sedano, B; Rotger, R; Ruscalleda, J1
Gan, R; Huang, B; Huang, Z; Nie, K; Wang, L; Zhang, Y; Zhao, J1

Reviews

2 review(s) available for n-acetylaspartic acid and Cognitive Dysfunction

ArticleYear
Proton MRS in mild cognitive impairment.
    Journal of magnetic resonance imaging : JMRI, 2013, Volume: 37, Issue:4

    Topics: Alzheimer Disease; Animals; Aspartic Acid; Biomarkers; Brain; Choline; Cognitive Dysfunction; Creatine; Dementia; Diagnosis, Differential; Disease Models, Animal; Disease Progression; Energy Metabolism; Humans; Inositol; Magnetic Resonance Spectroscopy; Mice; Translational Research, Biomedical

2013
Magnetic resonance spectroscopy in mild cognitive impairment: systematic review and meta-analysis.
    Neuroscience and biobehavioral reviews, 2013, Volume: 37, Issue:10 Pt 2

    Topics: Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Humans; Inositol; Magnetic Resonance Spectroscopy

2013

Other Studies

33 other study(ies) available for n-acetylaspartic acid and Cognitive Dysfunction

ArticleYear
The Auditory Afferent Pathway as a Clinical Marker of Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2022, Volume: 85, Issue:1

    Topics: Acoustic Stimulation; Afferent Pathways; Aged; Alzheimer Disease; Aspartic Acid; Biomarkers; Cerebral Cortex; Cognitive Dysfunction; Creatine; Electroencephalography; Evoked Potentials, Auditory; Female; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mental Status and Dementia Tests; Middle Aged; Temporal Lobe

2022
Brain N-Acetyl Aspartate and associations with cognitive impairment in alcohol dependent patients.
    Journal of clinical and experimental neuropsychology, 2020, Volume: 42, Issue:2

    Topics: Adult; Aged; Alcoholism; Aspartic Acid; Brain Chemistry; Cognitive Dysfunction; Female; Humans; Magnetic Resonance Spectroscopy; Male; Mental Status and Dementia Tests; Middle Aged; Neuropsychological Tests; Parietal Lobe; Risk-Taking; Trail Making Test

2020
Application of Hydrogen Proton Magnetic Resonance Technology Combined with Brain Neurometabolite Analysis in the Treatment of Cognitive Impairment Caused by Type 2 Diabetes Mellitus.
    World neurosurgery, 2020, Volume: 138

    Topics: Adult; Aged; Aspartic Acid; Cognitive Dysfunction; Diabetes Mellitus, Type 2; Female; Humans; Hydrogen; Male; Middle Aged; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Protons; Treatment Outcome

2020
Reduced Hippocampal Glutamate and Posterior Cingulate N-Acetyl Aspartate in Mild Cognitive Impairment and Alzheimer's Disease Is Associated with Episodic Memory Performance and White Matter Integrity in the Cingulum: A Pilot Study.
    Journal of Alzheimer's disease : JAD, 2020, Volume: 73, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Cognitive Dysfunction; Diffusion Tensor Imaging; Female; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Limbic System; Magnetic Resonance Spectroscopy; Male; Memory, Episodic; Mental Status and Dementia Tests; Middle Aged; Neuropsychological Tests; Pilot Projects; White Matter

2020
COVID-19-related cognitive dysfunction may be associated with transient disruption in the DLPFC glutamatergic pathway.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 87

    Topics: Adult; Aspartic Acid; Cognitive Dysfunction; COVID-19; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Signal Transduction

2021
Progressive Neurochemical Abnormalities in Cognitive and Motor Subgroups of Amyotrophic Lateral Sclerosis: A Prospective Multicenter Study.
    Neurology, 2021, 08-24, Volume: 97, Issue:8

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Aspartic Acid; Cognitive Dysfunction; Disease Progression; Female; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Cortex; Prefrontal Cortex; Severity of Illness Index

2021
Study on the clinical application of the MRS in the cognitive assessment after stroke.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:10

    Topics: Aspartic Acid; Cognition; Cognition Disorders; Cognitive Dysfunction; Creatine; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Stroke

2017
Decreased N-Acetyl Aspartate/Myo-Inositol Ratio in the Posterior Cingulate Cortex Shown by Magnetic Resonance Spectroscopy May Be One of the Risk Markers of Preclinical Alzheimer's Disease: A 7-Year Follow-Up Study.
    Journal of Alzheimer's disease : JAD, 2017, Volume: 60, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Biomarkers; Cognitive Dysfunction; Disease Progression; Female; Follow-Up Studies; Gyrus Cinguli; Humans; Inositol; Lewy Body Disease; Male; Mental Status and Dementia Tests; Parkinson Disease; Prodromal Symptoms; Proton Magnetic Resonance Spectroscopy; Retrospective Studies; Risk Factors

2017
7T Proton Magnetic Resonance Spectroscopy of the Anterior Cingulate Cortex in First-Episode Schizophrenia.
    Schizophrenia bulletin, 2019, 01-01, Volume: 45, Issue:1

    Topics: Adult; Aspartic Acid; Cognitive Dysfunction; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia; Young Adult

2019
Hippocampal metabolites in asthma and their implications for cognitive function.
    NeuroImage. Clinical, 2018, Volume: 19

    Topics: Adolescent; Adult; Aspartic Acid; Asthma; Cognition; Cognitive Dysfunction; Creatine; Female; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Young Adult

2018
White matter damage, neuroinflammation, and neuronal integrity in HAND.
    Journal of neurovirology, 2019, Volume: 25, Issue:1

    Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aspartic Acid; Basal Ganglia; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Choline; Cognitive Dysfunction; Creatine; Female; Gray Matter; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Memory, Short-Term; Middle Aged; Neuroimaging; Neuropsychological Tests; Organ Size; Severity of Illness Index; White Matter

2019
Proxies of cognitive reserve and their effects on neuropsychological performance in patients with mild cognitive impairment.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2013, Volume: 20, Issue:4

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Choline; Cognitive Dysfunction; Cognitive Reserve; Creatine; Diagnostic and Statistical Manual of Mental Disorders; Educational Status; Female; Hippocampus; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memory; Middle Aged; Neuropsychological Tests; Psychomotor Performance; Wechsler Scales

2013
Magnetic resonance imaging study cannot individually distinguish individuals with mild cognitive impairment, mild Alzheimer's disease, and normal aging.
    Arquivos de neuro-psiquiatria, 2013, Volume: 71, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Diagnosis, Differential; Female; Hippocampus; Humans; Inositol; Magnetic Resonance Imaging; Male; Mental Status Schedule; Severity of Illness Index

2013
The partial volume effect in the quantification of 1H magnetic resonance spectroscopy in Alzheimer's disease and aging.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 42, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Analysis of Variance; Aspartic Acid; Brain; Cognitive Dysfunction; Female; Functional Laterality; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons

2014
Proton magnetic resonance spectroscopy in mild cognitive impairment and Alzheimer's disease: a preliminary study.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014, Volume: 97, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Case-Control Studies; Choline; Cognitive Dysfunction; Creatine; Cross-Sectional Studies; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged

2014
Global N-acetylaspartate in normal subjects, mild cognitive impairment and Alzheimer's disease patients.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 43, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Biomarkers; Brain; Cognitive Dysfunction; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Sensitivity and Specificity

2015
[Prediction of conversion from amnestic mild cognitive impairment to Alzheimer's disease using proton magnetic resonance spectroscopy].
    Rinsho shinkeigaku = Clinical neurology, 2015, Volume: 55, Issue:10

    Topics: Aged; Alzheimer Disease; Amnesia; Aspartic Acid; Cognitive Dysfunction; Disease Progression; Female; Forecasting; Hippocampus; Humans; Male; Proton Magnetic Resonance Spectroscopy

2015
Metabolite ratios in the posterior cingulate cortex do not track cognitive decline in Parkinson's disease in a clinical setting.
    Parkinsonism & related disorders, 2016, Volume: 22

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Bayes Theorem; Case-Control Studies; Choline; Cognitive Dysfunction; Creatine; Dementia; Disease Progression; Female; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Superior Sagittal Sinus

2016
Altered posterior cingulate brain metabolites and cognitive dysfunction in preterm adolescents.
    Pediatric research, 2016, Volume: 79, Issue:5

    Topics: Adolescent; Aspartic Acid; Australia; Brain; Cell Membrane; Choline; Cognition; Cognition Disorders; Cognitive Dysfunction; Creatinine; Female; Gyrus Cinguli; Humans; Infant, Premature; Magnetic Resonance Spectroscopy; Male; Neurons; Prospective Studies; Regression Analysis; Treatment Outcome

2016
Proton magnetic resonance spectroscopy as a diagnostic biomarker in mild cognitive impairment following stroke in acute phase.
    Neuroreport, 2016, 05-25, Volume: 27, Issue:8

    Topics: Aged; Aspartic Acid; Biomarkers; Cognitive Dysfunction; Creatine; Female; Hippocampus; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Stroke

2016
(1)H-MRS asymmetry changes in the anterior and posterior cingulate gyrus in patients with mild cognitive impairment and mild Alzheimer's disease.
    Comprehensive psychiatry, 2016, Volume: 69

    Topics: Aged; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Dominance, Cerebral; Female; Gyrus Cinguli; Humans; Inositol; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy

2016
Metabolic alterations in the anterior cingulate cortex and related cognitive deficits in late adolescent methamphetamine users.
    Addiction biology, 2018, Volume: 23, Issue:1

    Topics: Adolescent; Amphetamine-Related Disorders; Aspartic Acid; Brain; Case-Control Studies; Cognitive Dysfunction; Female; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Methamphetamine; Proton Magnetic Resonance Spectroscopy; Stroop Test; Young Adult

2018
Post-WBRT cognitive impairment and hippocampal neuronal depletion measured by in vivo metabolic MR spectroscopy: Results of prospective investigational study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2017, Volume: 122, Issue:3

    Topics: Aspartic Acid; Biomarkers; Brain Neoplasms; Cognitive Dysfunction; Cranial Irradiation; Female; Follow-Up Studies; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Memory; Middle Aged; Nerve Degeneration; Neuropsychological Tests; Prospective Studies; Quality of Life; Surveys and Questionnaires

2017
Hippocampal proton MR spectroscopy in early Alzheimer's disease and mild cognitive impairment.
    Brain topography, 2011, Volume: 24, Issue:3-4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Case-Control Studies; Choline; Cognitive Dysfunction; Creatine; Female; Hippocampus; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Protons

2011
Using proton magnetic resonance spectroscopy to identify mild cognitive impairment.
    International psychogeriatrics, 2012, Volume: 24, Issue:1

    Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Case-Control Studies; Choline; Cognitive Dysfunction; Creatine; Female; Gyrus Cinguli; Hippocampus; Humans; Inositol; Magnetic Resonance Imaging; Male; Neuroimaging

2012
Association of N-acetylaspartate and cerebrospinal fluid Aβ42 in dementia.
    Journal of Alzheimer's disease : JAD, 2011, Volume: 27, Issue:2

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aspartic Acid; Biomarkers; Cognitive Dysfunction; Dementia; Female; Humans; Male; Middle Aged; Mitochondria; Neurons; Peptide Fragments

2011
Brain glutamate levels are decreased in Alzheimer's disease: a magnetic resonance spectroscopy study.
    American journal of Alzheimer's disease and other dementias, 2011, Volume: 26, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Cross-Sectional Studies; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Severity of Illness Index

2011
N-acetylaspartate, choline, myoinositol, glutamine and glutamate (glx) concentration changes in proton MR spectroscopy (1H MRS) in patients with mild cognitive impairment (MCI).
    Medical science monitor : international medical journal of experimental and clinical research, 2011, Volume: 17, Issue:12

    Topics: Aged; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Temporal Lobe

2011
Contribution of 1H spectroscopy to a brief cognitive-functional test battery for the diagnosis of mild Alzheimer's disease.
    Dementia and geriatric cognitive disorders, 2011, Volume: 32, Issue:5

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Cognitive Dysfunction; Creatine; Diagnosis, Differential; Female; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Mental Status Schedule; Neuropsychological Tests; Parietal Lobe; Predictive Value of Tests; Reference Values; Temporal Lobe

2011
Longitudinal magnetic resonance spectroscopy as marker of cognitive deterioration in mild cognitive impairment.
    American journal of Alzheimer's disease and other dementias, 2011, Volume: 26, Issue:8

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Brain; Cognitive Dysfunction; Creatine; Female; Follow-Up Studies; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Middle Aged

2011
Functional investigation of bilateral posterior cingulate gyri using multivoxel MR spectroscopy.
    European neurology, 2012, Volume: 67, Issue:5

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Cognitive Dysfunction; Creatine; Female; Functional Laterality; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Republic of Korea; Retrospective Studies; Statistics as Topic

2012
Spectroscopic changes associated with mild cognitive impairment and dementia in Parkinson's disease.
    Dementia and geriatric cognitive disorders, 2012, Volume: 34, Issue:5-6

    Topics: Aged, 80 and over; Aspartic Acid; Brain Chemistry; Cognition; Cognitive Dysfunction; Data Interpretation, Statistical; Dementia; Disease Progression; Executive Function; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Prefrontal Cortex; Psychiatric Status Rating Scales; Psychomotor Performance; Temporal Lobe; Tomography, X-Ray Computed

2012
Marked N-acetylaspartate and choline metabolite changes in Parkinson's disease patients with mild cognitive impairment.
    Parkinsonism & related disorders, 2013, Volume: 19, Issue:3

    Topics: Aged; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Choline; Cognitive Dysfunction; Early Diagnosis; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Parkinson Disease

2013