Page last updated: 2024-08-24

n-acetylaspartic acid and Chronic Disease

n-acetylaspartic acid has been researched along with Chronic Disease in 57 studies

Research

Studies (57)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	11 (19.30)	18.2507
2000's	33 (57.89)	29.6817
2010's	12 (21.05)	24.3611
2020's	1 (1.75)	2.80

Authors

Authors	Studies
Attard, KJ; Boyd, LA; Ferris, JK; Greeley, B; Hayward, KS; MacKay, AL; Neva, JL; Vavasour, IM; Wadden, KP	1
Chen, WT; Fuh, JL; Lai, KL; Lin, YR; Niddam, DM; Tsai, SY; Wang, SJ	1
Abe, O; Aoki, Y; Gonoi, W; Inoue, H; Iwashiro, N; Kasai, K; Katsura, M; Koike, S; Natsubori, T; Sasaki, H; Takano, Y; Takao, H; Yahata, N; Yamasue, H	1
Alger, JR; Brown, M; Buchthal, S; Campbell, TB; Cohen, R; Daar, ES; Gongvatana, A; Harezlak, J; McMahon, D; Navia, BA; Schifitto, G; Singer, EJ; So, YT; Taylor, M; Yiannoutsos, CT; Zhong, J	1
Gao, S; Peng, GJ; Qin, XM; Shi, BY; Tian, JS	1
Carr, RA; Colrain, IM; Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Zahr, NM	1
Bigal, M; Brito, C; Jevoux, C; Moreira, P; Sarmento, E; Souza, J	1
Backens, M; Berner, D; Falkai, P; Gruber, O; Honer, WG; Kaizl, I; Kierer, A; Meyer, T; Müller, S; Oest, M; Pajonk, FG; Scherk, H; Schneider-Axmann, T; Thornton, AE; Wobrock, T	1
Cohen, BM; McCarthy, J; Ongür, D; Prescot, AP; Renshaw, PF	1
Dasilva, D; Freedman, SD; Fregni, F; Lenkinski, RE; Pascual-Leone, A; Potvin, K; Wang, X	1
Barker, PB; Conant, K; Degaonkar, M; Halpern, EF; Kim, H; Lentz, MR; Mohamed, MA; Pomper, MG; Sacktor, N	1
de Diego-Adeliño, J; Gómez-Ansón, B; Morgan-Ferrando, R; Pérez, V; Pérez-Egea, R; Portella, MJ; Puigdemont, D; Ruscalleda, J; Vives, Y	1
Durazzo, TC; Gazdzinski, S; Meyerhoff, DJ; Mon, A	1
Choi, IY; Lee, P; Smirnova, IV; Wang, WT; Yeh, HW	1
Benedetti, C; Catani, M; Cherubini, A; Howard, R; Mariani, E; Mecocci, P; Metastasio, A; Pelliccioli, GP; Senin, U; Tarducci, R	1
Alperin, N; Chu, Y; Emborg, ME; Khan, N; Kompoliti, K; Kordower, JH; Roitberg, B; Tuccar, E	1
Fredrickson, BE; Grachev, ID; Ramachandran, TS; Szeverenyi, NM; Thomas, PS	1
Beley, A; Bertrand, N; Demougeot, C; Garnier, P; Giroud, M; Marie, C; Mossiat, C; Prigent-Tessier, A	1
Holburn, GH; Lee, H; Price, RR	1
Fukui, S	1
Fukuda, R; Fukui, T; Iwanami, A; Kasai, K; Kato, N; Kato, T; Yamasue, H	1
Al-Semaan, Y; Densmore, M; Drost, DJ; Menon, RS; Neufeld, RW; Rajakumar, N; Schaefer, B; Théberge, J; Williamson, PC	1
Fuller, RA; González, RG; Greco, JB; Halpern, E; He, J; Kim, JP; Lackner, AA; Lentz, MR; Masliah, E; Ratai, E; Sehgal, PK; Westmoreland, SV	1
Burneo, JG; Faught, E; Knowlton, RC; Kuzniecky, RI; Martin, R; Sawrie, S	1
Arolt, V; Heindel, W; Kersting, A; Ohrmann, P; Pfleiderer, B; Siegmund, A; Spitzberg, K; Suslow, T	1
Benito, C; Desco, M; Gispert, JD; Misiego, JM; Molina, V; Palomo, T; Pascau, J; Reig, S; Sánchez, J; Santamarta, C; Sanz, J; Sarramea, F	1
Chang, L; Ernst, T; Grob, CS; Speck, O	1
Prockop, LD	1
Luo, L; Meng, XM; Ruan, DY; She, JQ; Zhu, DM	1
Chen, JJ; Fuh, JL; Lirng, JF; Wang, SJ	1
Barbiroli, B; Bivona, G; Cevoli, S; Cortelli, P; Lodi, R; Magnifico, F; Montagna, P; Pierangeli, G; Testa, C; Tonon, C	1
Arolt, V; Heindel, W; Kersting, A; Ohrmann, P; Pedersen, A; Pfleiderer, B; Rothermundt, M; Siegmund, A; Spitzberg, K; Suslow, T	1
Benito, C; Desco, M; Leal, I; Molina, V; Palomo, T; Rebolledo, R; Reig, S; Sánchez, J; Sanz, J; Sarramea, F	1
Gupta, RK; Nath, K; Radha Krishna, Y; Saraswat, VA; Thomas, MA; Verma, A	1
Dickstein, DP; Knopf, L; Leibenluft, E; Pine, DS; Towbin, KE; van der Veen, JW	1
Andermann, F; Arnold, DL; Cendes, F; Silver, K	1
Akimoto, H; Fujimoto, T; Fukuzako, T; Nakano, T; Takano, T; Takeuchi, K; Yamada, K	1
Gonzalez-Scarano, F; Grossman, RI; Kimura, H; Lenkinski, RE	1
Carr, TJ; Drost, DJ; Malla, A; Rylett, RJ; Stanley, JA; Thompson, RT; Williamson, PC	1
Handa, Y; Kaneko, M; Kobayashi, H; Kubota, T; Matuda, T	1
Harada, M; Miyoshi, H; Nishitani, H; Ootsuka, H; Tanouchi, M; Taoka, Y	1
Li, SJ; Pankiewicz, J; Stein, EA; Wang, Y	1
Helms, G; Kivisäkk, P; Link, H; Stawiarz, L	1
Braus, DF; Ende, G; Henn, FA; Maudsley, AA; Soher, B; Walter, S; Weber-Fahr, W	1
Apkarian, VA; Fredrickson, BE; Grachev, ID	1
Bjartmar, C; Kidd, G; Mörk, S; Rudick, R; Trapp, BD	1
Bustillo, JR; Lauriello, J; Rowland, L	1
King, CY; Villarreal, G	1
Grachev, ID	1
Apkarian, AV; Fredickson, BE; Grachev, ID	1
Braus, DF; Demirakca, T; Ende, G; Henn, FA; Tost, H; Weber-Fahr, W	1
Gaily, E; Granström, ML; Häkkinen, AM; Liukkonen, E; Lundbom, N; Paetau, R; Rajapakse, JC; Valanne, L; Vuori, K	1
Grachev, ID; Ramachandran, TS; Thomas, PS	1
Calabrese, G; Deicken, R; Fein, G; Fisher, SN; Hetherington, HP; Sappey-Marinier, D; Van Dyke, C; Weiner, MW	1
Christiansen, P; Frederiksen, J; Heltberg, A; Henriksen, O; Jensen, M; Larsson, HB; Olesen, J	1
Andermann, F; Arnold, DL; Matthews, PM	1
Antel, J; Arnold, DL; Francis, G; Matthews, PM	1

Reviews

3 review(s) available for n-acetylaspartic acid and Chronic Disease

Article	Year
N-acetyl-aspartate levels in the dorsolateral prefrontal cortex in the early years of schizophrenia are inversely related to disease duration. Schizophrenia research, 2005, Mar-01, Volume: 73, Issue:2-3 Topics: Adult; Age Factors; Antipsychotic Agents; Aspartic Acid; Choline; Chronic Disease; Creatine; Female; Functional Laterality; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Risperidone; Schizophrenia; Time Factors	2005
Proton magnetic resonance spectroscopy (H-MRS) studies of schizophrenia. Seminars in clinical neuropsychiatry, 2001, Volume: 6, Issue:2 Topics: Aspartic Acid; Brain Chemistry; Chronic Disease; Frontal Lobe; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Schizophrenia; Temporal Lobe	2001
Brain imaging in posttraumatic stress disorder. Seminars in clinical neuropsychiatry, 2001, Volume: 6, Issue:2 Topics: Amygdala; Arousal; Aspartic Acid; Atrophy; Brain; Chronic Disease; Cognition; Fear; Hippocampus; Humans; Limbic System; Magnetic Resonance Imaging; Models, Neurological; Stress Disorders, Post-Traumatic; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon	2001

Trials

4 trial(s) available for n-acetylaspartic acid and Chronic Disease

Article	Year
Hippocampal plasticity in response to exercise in schizophrenia. Archives of general psychiatry, 2010, Volume: 67, Issue:2 Topics: Adult; Aspartic Acid; Chronic Disease; Cognition Disorders; Exercise; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuronal Plasticity; Neuropsychological Tests; Schizophrenia	2010
Clinical effects and brain metabolic correlates in non-invasive cortical neuromodulation for visceral pain. European journal of pain (London, England), 2011, Volume: 15, Issue:1 Topics: Adult; Analgesia; Aspartic Acid; Brain; Chronic Disease; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pain; Pain Management; Pancreatitis, Chronic; Radionuclide Imaging; Severity of Illness Index; Somatosensory Cortex; Transcranial Magnetic Stimulation; Treatment Outcome	2011
Proton magnetic resonance spectroscopy in youth with severe mood dysregulation. Psychiatry research, 2008, May-30, Volume: 163, Issue:1 Topics: Antimanic Agents; Arousal; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Brain Mapping; Cerebral Cortex; Chronic Disease; Creatine; Diagnosis, Differential; Dominance, Cerebral; Double-Blind Method; Glutamine; Humans; Image Processing, Computer-Assisted; Inositol; Irritable Mood; Lithium Compounds; Magnetic Resonance Spectroscopy; Mood Disorders; Phosphocreatine	2008
Regression analysis of metabolite concentrations estimated from localized proton MR spectra of active and chronic multiple sclerosis lesions. Magnetic resonance in medicine, 2000, Volume: 43, Issue:1 Topics: Acute Disease; Adult; Aged; Aspartic Acid; Brain; Chronic Disease; Contrast Media; Creatine; Female; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Phosphoric Monoester Hydrolases; Reference Values; Regression Analysis	2000

Other Studies

50 other study(ies) available for n-acetylaspartic acid and Chronic Disease

Article	Year
Cortical N-acetylaspartate concentrations are impacted in chronic stroke but do not relate to motor impairment: A magnetic resonance spectroscopy study. Human brain mapping, 2021, Volume: 42, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Chronic Disease; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Activity; Sensorimotor Cortex; Stroke; Upper Extremity	2021
Neurochemical changes in the medial wall of the brain in chronic migraine. Brain : a journal of neurology, 2018, 02-01, Volume: 141, Issue:2 Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Brain Mapping; Chronic Disease; Correlation of Data; Creatine; Female; Glutamic Acid; Glutamine; Humans; Inositol; Male; Migraine Disorders; Severity of Illness Index; Statistics, Nonparametric; Taiwan; Young Adult	2018
Reduced frontal glutamate + glutamine and N-acetylaspartate levels in patients with chronic schizophrenia but not in those at clinical high risk for psychosis or with first-episode schizophrenia. Schizophrenia bulletin, 2014, Volume: 40, Issue:5 Topics: Adolescent; Adult; Aspartic Acid; Chronic Disease; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Prodromal Symptoms; Psychotic Disorders; Risk; Schizophrenia; Young Adult	2014
Predictors of CNS injury as measured by proton magnetic resonance spectroscopy in the setting of chronic HIV infection and CART. Journal of neurovirology, 2014, Volume: 20, Issue:3 Topics: Adult; AIDS Dementia Complex; Anti-Retroviral Agents; Aspartic Acid; Basal Ganglia; Choline; Chronic Disease; Creatine; Female; Frontal Lobe; Gray Matter; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Protons; White Matter	2014
[1H NMR based metabonomics study on the antidepressant effect of genipin in rat hippocampus]. Yao xue xue bao = Acta pharmaceutica Sinica, 2014, Volume: 49, Issue:2 Topics: Alanine; Animals; Antidepressive Agents; Aspartic Acid; Behavior, Animal; Chronic Disease; Depression; Gardenia; Glutamic Acid; Glycine; Hippocampus; Inositol; Iridoids; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Metabolomics; Plants, Medicinal; Rats; Rats, Sprague-Dawley	2014
Brain metabolite levels in recently sober individuals with alcohol use disorder: Relation to drinking variables and relapse. Psychiatry research. Neuroimaging, 2016, Apr-30, Volume: 250 Topics: Adult; Alcohol Abstinence; Alcohol Drinking; Alcoholism; Aspartic Acid; Brain; Choline; Chronic Disease; Creatine; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Recurrence	2016
Proton spectroscopy in patients with post-traumatic headache attributed to mild head injury. Headache, 2009, Volume: 49, Issue:9 Topics: Adolescent; Adult; Aged; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Injuries; Brain Mapping; Cell Membrane; Choline; Chronic Disease; Craniocerebral Trauma; Female; Headache; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Severity of Illness Index; Young Adult	2009
Elevated gamma-aminobutyric acid levels in chronic schizophrenia. Biological psychiatry, 2010, Oct-01, Volume: 68, Issue:7 Topics: Adult; Analysis of Variance; Aspartic Acid; Case-Control Studies; Chronic Disease; Creatine; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Radionuclide Imaging; Schizophrenia	2010
Exploring the relationship of macrophage colony-stimulating factor levels on neuroaxonal metabolism and cognition during chronic human immunodeficiency virus infection. Journal of neurovirology, 2010, Volume: 16, Issue:5 Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aspartic Acid; Biomarkers; Brain; Chronic Disease; Cognition; Cohort Studies; Female; HIV-1; Humans; Macrophage Colony-Stimulating Factor; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Prognosis	2010
Ventromedial prefrontal spectroscopic abnormalities over the course of depression: a comparison among first episode, remitted recurrent and chronic patients. Journal of psychiatric research, 2011, Volume: 45, Issue:4 Topics: Adult; Age of Onset; Aspartic Acid; Choline; Chronic Disease; Depressive Disorder, Major; Disease Progression; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multivariate Analysis; Prefrontal Cortex	2011
Chronic cigarette smoking in alcohol dependence: associations with cortical thickness and N-acetylaspartate levels in the extended brain reward system. Addiction biology, 2013, Volume: 18, Issue:2 Topics: Adult; Aged; Alcoholism; Aspartic Acid; Behavior, Addictive; Brain Mapping; Case-Control Studies; Cerebral Cortex; Chronic Disease; Comorbidity; Executive Function; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Multivariate Analysis; Reward; Smoking	2013
Effects of acute and chronic hyperglycemia on the neurochemical profiles in the rat brain with streptozotocin-induced diabetes detected using in vivo ¹H MR spectroscopy at 9.4 T. Journal of neurochemistry, 2012, Volume: 121, Issue:3 Topics: Acute Disease; Algorithms; Animals; Aspartic Acid; Biological Transport, Active; Blood Glucose; Blood-Brain Barrier; Brain Chemistry; Cerebral Cortex; Chronic Disease; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Progression; Glucose; Glutathione; Hippocampus; Hyperglycemia; Kinetics; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley	2012
Proton magnetic resonance spectroscopy reveals similar white matter biochemical changes in patients with chronic hypertension and early Alzheimer's disease. Journal of the American Geriatrics Society, 2002, Volume: 50, Issue:10 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Brain; Choline; Chronic Disease; Creatine; Cross-Sectional Studies; Female; Humans; Hypertension; Inositol; Magnetic Resonance Spectroscopy; Male	2002
Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical study. Neurological research, 2003, Volume: 25, Issue:1 Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Chronic Disease; Follow-Up Studies; Immunohistochemistry; Infarction, Middle Cerebral Artery; Macaca fascicularis; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Models, Animal; Motor Skills; Radiography	2003
Association between dorsolateral prefrontal N-acetyl aspartate and depression in chronic back pain: an in vivo proton magnetic resonance spectroscopy study. Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:3 Topics: Adult; Aspartic Acid; Back Pain; Chronic Disease; Depression; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Protons; Statistics, Nonparametric	2003
Reversible loss of N-acetyl-aspartate in rats subjected to long-term focal cerebral ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:4 Topics: Animals; Aspartic Acid; Brain Ischemia; Chromatography, High Pressure Liquid; Chronic Disease; Male; Neuroglia; Neurons; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Stroke	2003
Proton MR spectroscopic studies of chronic alcohol exposure on the rat brain. Journal of magnetic resonance imaging : JMRI, 2003, Volume: 18, Issue:2 Topics: Alcoholism; Animals; Aspartic Acid; Brain; Choline; Chronic Disease; Creatine; Magnetic Resonance Spectroscopy; Male; Protons; Rats; Rats, Sprague-Dawley; Time	2003
Evaluation of thalamic neural activity in CRPS type 1 patients by proton MR spectroscopy: a correlative study with rCBF. Journal of anesthesia, 2003, Volume: 17, Issue:2 Topics: Adult; Aspartic Acid; Cerebrovascular Circulation; Chronic Disease; Creatine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reflex Sympathetic Dystrophy; Thalamus; Tomography, X-Ray Computed	2003
Drug-induced parkinsonism in relation to choline-containing compounds measured by 1H-MR spectroscopy in putamen of chronically medicated patients with schizophrenia. The international journal of neuropsychopharmacology, 2003, Volume: 6, Issue:4 Topics: Adult; Antipsychotic Agents; Aspartic Acid; Basal Ganglia Diseases; Choline; Chronic Disease; Creatine; Dominance, Cerebral; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurologic Examination; Parkinson Disease, Secondary; Phosphocreatine; Putamen; Reference Values; Schizophrenia; Schizophrenic Psychology	2003
Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS. The American journal of psychiatry, 2003, Volume: 160, Issue:12 Topics: Adult; Antipsychotic Agents; Aspartic Acid; Chronic Disease; Dominance, Cerebral; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Degeneration; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Thalamus	2003
A prospective longitudinal in vivo 1H MR spectroscopy study of the SIV/macaque model of neuroAIDS. BMC neuroscience, 2004, Mar-05, Volume: 5 Topics: Acute Disease; AIDS Dementia Complex; Animals; Aspartic Acid; Brain; Choline; Chronic Disease; Creatine; Disease Models, Animal; Disease Progression; Female; Inositol; Longitudinal Studies; Macaca mulatta; Magnetic Resonance Spectroscopy; Male; Predictive Value of Tests; Prospective Studies; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Survival Rate; Viral Load	2004
Chronic temporal lobe epilepsy: spatial extent and degree of metabolic dysfunction studied with magnetic resonance spectroscopy (MRS). Epilepsy research, 2004, Volume: 62, Issue:2-3 Topics: Adolescent; Adult; Aspartic Acid; Child; Child, Preschool; Chronic Disease; Creatine; Electroencephalography; Epilepsy, Temporal Lobe; Female; Functional Laterality; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Time Factors	2004
Evidence for glutamatergic neuronal dysfunction in the prefrontal cortex in chronic but not in first-episode patients with schizophrenia: a proton magnetic resonance spectroscopy study. Schizophrenia research, 2005, Mar-01, Volume: 73, Issue:2-3 Topics: Adult; Aspartic Acid; Chronic Disease; Diagnostic and Statistical Manual of Mental Disorders; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Prefrontal Cortex; Protons; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Synaptic Transmission	2005
Additive effects of HIV and chronic methamphetamine use on brain metabolite abnormalities. The American journal of psychiatry, 2005, Volume: 162, Issue:2 Topics: Adult; Amphetamine-Related Disorders; Aspartic Acid; Basal Ganglia; Brain; Brain Diseases; Choline; Chronic Disease; Comorbidity; Creatine; Female; Frontal Lobe; HIV Seronegativity; HIV Seropositivity; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Methamphetamine	2005
Carbon monoxide brain toxicity: clinical, magnetic resonance imaging, magnetic resonance spectroscopy, and neuropsychological effects in 9 people. Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2005, Volume: 15, Issue:2 Topics: Acute Disease; Adolescent; Adult; Aspartic Acid; Basal Ganglia; Brain; Carbon Monoxide Poisoning; Child; Chronic Disease; Cognition; Coma; Comprehension; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mental Processes; Neuropsychological Tests; Parkinson Disease, Secondary; Thinking; Unconsciousness	2005
Effects of chronic lead exposure on 1H MRS of hippocampus and frontal lobes in children. Neurology, 2005, May-10, Volume: 64, Issue:9 Topics: Aspartic Acid; Cell Membrane; Cell Survival; Child; Choline; Chronic Disease; Cognition Disorders; Creatine; Energy Metabolism; Environmental Exposure; Female; Frontal Lobe; Functional Laterality; Hippocampus; Humans; Lead; Lead Poisoning, Nervous System, Childhood; Magnetic Resonance Spectroscopy; Male; Mitochondria; Neurons; Phospholipids	2005
Reduction in hypothalamic 1H-MRS metabolite ratios in patients with cluster headache. Journal of neurology, neurosurgery, and psychiatry, 2006, Volume: 77, Issue:5 Topics: Adult; Aspartic Acid; Choline; Chronic Disease; Cluster Headache; Creatinine; Diagnosis, Differential; Dominance, Cerebral; Female; Follow-Up Studies; Humans; Hypothalamus; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Migraine Disorders; Reference Values; Statistics as Topic	2006
Study of hypothalamic metabolism in cluster headache by proton MR spectroscopy. Neurology, 2006, Apr-25, Volume: 66, Issue:8 Topics: Acute Disease; Adult; Aged; Aspartic Acid; Biomarkers; Cerebral Cortex; Chronic Disease; Cluster Headache; Creatine; Female; Humans; Hypothalamus; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Occipital Lobe; Parietal Lobe; Protons	2006
Cognitive impairment and in vivo metabolites in first-episode neuroleptic-naive and chronic medicated schizophrenic patients: a proton magnetic resonance spectroscopy study. Journal of psychiatric research, 2007, Volume: 41, Issue:8 Topics: Adult; Aged; Antipsychotic Agents; Aspartic Acid; Choline; Chronic Disease; Cognition Disorders; Creatine; Dominance, Cerebral; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mental Recall; Middle Aged; Neurons; Phosphocreatine; Prefrontal Cortex; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Verbal Learning	2007
Dorsolateral prefrontal N-acetyl-aspartate concentration in male patients with chronic schizophrenia and with chronic bipolar disorder. European psychiatry : the journal of the Association of European Psychiatrists, 2007, Volume: 22, Issue:8 Topics: Adult; Aspartic Acid; Bipolar Disorder; Cerebrospinal Fluid; Choline; Chronic Disease; Creatine; Fourier Analysis; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Prefrontal Cortex; Reference Values; Schizophrenia	2007
In vivo 1H magnetic resonance spectroscopy-derived metabolite variations between acute-on-chronic liver failure and acute liver failure. Liver international : official journal of the International Association for the Study of the Liver, 2008, Volume: 28, Issue:8 Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Case-Control Studies; Choline; Chronic Disease; Creatine; Female; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Humans; Inositol; Liver Failure, Acute; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Young Adult	2008
Imaging of axonal damage in vivo in Rasmussen's syndrome. Brain : a journal of neurology, 1995, Volume: 118 ( Pt 3) Topics: Adolescent; Aspartic Acid; Brain Chemistry; Child; Chronic Disease; Creatine; Disease Progression; Encephalitis; Epilepsies, Partial; Female; Hemiplegia; Humans; Magnetic Resonance Imaging; Male; Status Epilepticus; Syndrome	1995
Proton magnetic resonance spectroscopy of basal ganglia in chronic schizophrenia. Biological psychiatry, 1996, Jul-01, Volume: 40, Issue:1 Topics: Adult; Aspartic Acid; Basal Ganglia; Basal Ganglia Diseases; Brain Mapping; Choline; Chronic Disease; Creatine; Dominance, Cerebral; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurocognitive Disorders; Phosphocreatine; Protons; Psychiatric Status Rating Scales; Schizophrenia	1996
Proton MR spectroscopy and magnetization transfer ratio in multiple sclerosis: correlative findings of active versus irreversible plaque disease. AJNR. American journal of neuroradiology, 1996, Volume: 17, Issue:8 Topics: Adult; Aspartic Acid; Brain; Brain Diseases; Brain Edema; Choline; Chronic Disease; Creatine; Demyelinating Diseases; Encephalitis; Female; Humans; Image Enhancement; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Protons	1996
An in vivo proton magnetic resonance spectroscopy study of schizophrenia patients. Schizophrenia bulletin, 1996, Volume: 22, Issue:4 Topics: Adolescent; Adult; Antipsychotic Agents; Aspartic Acid; Chronic Disease; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology	1996
In vivo proton magnetic resonance spectroscopy for metabolic changes in brain during chronic cerebral vasospasm in primates. Neurosurgery, 1997, Volume: 40, Issue:4 Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Cerebral Angiography; Cerebrovascular Circulation; Choline; Chronic Disease; Cognition Disorders; Creatinine; Energy Metabolism; Female; Ischemic Attack, Transient; Macaca fascicularis; Magnetic Resonance Imaging; Neurons; Phosphocreatine; Subarachnoid Hemorrhage	1997
[Accuracy and clinical utility of quantitative proton magnetic resonance spectroscopy (MRS) on phantom and chronic cerebral ischemia]. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1997, Volume: 57, Issue:8 Topics: Aspartic Acid; Brain; Brain Ischemia; Chronic Disease; Creatine; Humans; Magnetic Resonance Spectroscopy; Phantoms, Imaging; Phosphocreatine; Sensitivity and Specificity	1997
Neurochemical adaptation to cocaine abuse: reduction of N-acetyl aspartate in thalamus of human cocaine abusers. Biological psychiatry, 1999, Jun-01, Volume: 45, Issue:11 Topics: Adult; Aspartic Acid; Basal Ganglia; Biomarkers; Brain Chemistry; Case-Control Studies; Choline; Chronic Disease; Cocaine; Cocaine-Related Disorders; Creatine; Dopamine Uptake Inhibitors; Female; Humans; Magnetic Resonance Spectroscopy; Male; Thalamus	1999
Effects of age, medication, and illness duration on the N-acetyl aspartate signal of the anterior cingulate region in schizophrenia. Schizophrenia research, 2000, Feb-14, Volume: 41, Issue:3 Topics: Adult; Antipsychotic Agents; Aspartic Acid; Chronic Disease; Clozapine; Creatine; Female; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Reference Values; Risperidone; Schizophrenia; Treatment Outcome	2000
Abnormal brain chemistry in chronic back pain: an in vivo proton magnetic resonance spectroscopy study. Pain, 2000, Dec-15, Volume: 89, Issue:1 Topics: Adult; Anxiety; Aspartic Acid; Back Pain; Brain Chemistry; Choline; Chronic Disease; Creatine; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Thalamus	2000
Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients. Annals of neurology, 2000, Volume: 48, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Axons; Chronic Disease; Disability Evaluation; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Spinal Cord	2000
Spectroscopic brain mapping the N-acetyl aspartate to cognitive-perceptual states in chronic pain. Molecular psychiatry, 2001, Volume: 6, Issue:2 Topics: Aspartic Acid; Back Pain; Brain Chemistry; Brain Mapping; Chronic Disease; Cognition; Humans	2001
Dissociating anxiety from pain: mapping the neuronal marker N-acetyl aspartate to perception distinguishes closely interrelated characteristics of chronic pain. Molecular psychiatry, 2001, Volume: 6, Issue:3 Topics: Anxiety; Aspartic Acid; Brain Chemistry; Brain Mapping; Chronic Disease; Humans; Neurons; Pain	2001
Functioning and neuronal viability of the anterior cingulate neurons following antipsychotic treatment: MR-spectroscopic imaging in chronic schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2002, Volume: 12, Issue:2 Topics: Adult; Antipsychotic Agents; Aspartic Acid; Cell Survival; Chronic Disease; Cross-Sectional Studies; Female; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Neuropsychological Tests; Schizophrenia	2002
Proton spectroscopic imaging shows abnormalities in glial and neuronal cell pools in frontal lobe epilepsy. Epilepsia, 2001, Volume: 42, Issue:12 Topics: Adolescent; Adult; Aspartic Acid; Brain; Child; Child, Preschool; Chronic Disease; Creatine; Electroencephalography; Epilepsy, Frontal Lobe; Female; Frontal Lobe; Functional Laterality; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Monitoring, Physiologic; Neuroglia; Neurons; Parietal Lobe; Phosphocreatine; Videotape Recording	2001
Decreased levels of N-acetylaspartate in dorsolateral prefrontal cortex in a case of intractable severe sympathetically mediated chronic pain (complex regional pain syndrome, type I). Brain and cognition, 2002, Volume: 49, Issue:1 Topics: Adult; Anxiety Disorders; Aspartic Acid; Chronic Disease; Depressive Disorder, Major; Female; Humans; Magnetic Resonance Imaging; Pain; Pain Measurement; Prefrontal Cortex	2002
Proton magnetic resonance spectroscopy of human brain: applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities. Magnetic resonance in medicine, 1992, Volume: 26, Issue:2 Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Chemistry; Brain Ischemia; Cerebral Infarction; Choline; Chronic Disease; Creatine; Female; Humans; Hydrogen; Image Enhancement; Inositol; Lactates; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged	1992
Localized in vivo proton spectroscopy in the brain of patients with multiple sclerosis. Magnetic resonance in medicine, 1991, Volume: 22, Issue:1 Topics: Acute Disease; Adult; Aspartic Acid; Brain; Choline; Chronic Disease; Female; Humans; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Multiple Sclerosis	1991
A proton magnetic resonance spectroscopy study of focal epilepsy in humans. Neurology, 1990, Volume: 40, Issue:6 Topics: Aspartic Acid; Brain; Child; Chronic Disease; Encephalitis; Epilepsies, Partial; Female; Humans; Lactates; Magnetic Resonance Spectroscopy; Male	1990
Proton magnetic resonance spectroscopy of human brain in vivo in the evaluation of multiple sclerosis: assessment of the load of disease. Magnetic resonance in medicine, 1990, Volume: 14, Issue:1 Topics: Aspartic Acid; Brain; Chronic Disease; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Multiple Sclerosis; Protons	1990