Compounds > n-acetylaspartic acid
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n-acetylaspartic acid and Brain Injuries

n-acetylaspartic acid has been researched along with Brain Injuries in 89 studies

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.12)18.7374
1990's9 (10.11)18.2507
2000's47 (52.81)29.6817
2010's31 (34.83)24.3611
2020's1 (1.12)2.80

Authors

AuthorsStudies
Gao, J; Han, D; Li, J; Li, Q; Liao, C; Luo, Y; Wang, R; Yang, J1
Basu, SK; Chang, T; Kapse, K; Limperopoulos, C; McCarter, R; Murnick, J; Pradhan, S1
Berkefeld, J; Güresir, E; Hattingen, E; Hildebrand, C; Jurcoane, A; Pilatus, U; Vatter, H; Wagner, M; Zanella, FE1
Chang, C; Chang, L; Denny, K; Ernst, T; Green, D; O'Phelan, K; Park, D; Stenger, A1
Bandak, F; de Lanerolle, NC; Hamid, H; Hetherington, HP; Kulas, J; Ling, G; Pan, JW1
Bittšanský, M; Demková, A; Dobrota, D; Grossmann, J; Hnilicová, P; Kantorová, E; Kurča, E; Nosál', V; Sivák, Š; Siváková, J1
Babb, JS; Gonen, O; Grossman, RI; Haemer, G; Kierans, AS; Kirov, II; Lui, YW; Nisenbaum, E1
Amorini, AM; Belli, A; Di Pietro, V; Lazzarino, G; Logan, A; Signoretti, S; Tavazzi, B; Vagnozzi, R1
Chen, WS; Hong, L; Li, CQ; Li, JJ; Wang, F; Xing, ZB; Zhang, JH1
Fievisohn, EM; Hardy, WN; Sajja, VS; Vandevord, PJ1
Davitz, MS; Fieremans, E; Gonen, O; Grossman, EJ; Grossman, RI; Inglese, M; Kirov, II; Lui, YW; Novikov, DS1
Han, L; Hao, S; Hou, Z; Liu, B; Mao, X; Tao, X; Tian, R; Zhang, Q; Zhu, Z1
Carvalho, F; Carvalho, RA; Cunha, RA; Fonseca, R; Fontes Ribeiro, CA; Jarak, I; Köfalvi, A; Lemos, C; Pereira, FC; Pita, IR; Prediger, RD; Sequeira, AC; Silva, CD1
Hoch, SE; Kirov, II; Tal, A1
Gröhn, H; Gröhn, OH; Immonen, RJ; Kharatishvili, I; Niskanen, JP; Pitkänen, A1
Campistol, J; Capdevila, A; De La Osa, A; García-Cazorla, A; Leist, A; Navarro-Sastre, A; Pérez-Dueñas, B; Pineda, M; Ribes, A; Serrano, M1
Aygok, GA; Bullock, RM; Fatouros, P; Kettenmann, B; Marmarou, A1
Amaro, E; Nucci-da-Silva, MP1
Bigal, M; Brito, C; Jevoux, C; Moreira, P; Sarmento, E; Souza, J1
Amorini, AM; Belli, A; D'Urso, S; Di Pietro, V; Lazzarino, G; Signoretti, S; Tavazzi, B; Vagnozzi, R1
Chen, XR; Fulla-Oller, L; Gillet, B; Lescot, T; Marchand-Leroux, C; Meric, P; Plotkine, M; Po, C; Puybasset, L1
Ariyannur, PS; Arun, P; Grunberg, NE; Hamilton, K; Ives, JA; Moffett, JR; Namboodiri, AM; Xing, G1
Blamek, S; Ficek, K; Miszczyk, L; Sońta-Jakimczyk, D; Syguła, D; Tarnawski, R1
Alger, JR; Asarnow, RF; Babikian, T; Cazalis, F; Copeland, S; Giza, CC; Hilleary, SM; Kernan, CL; Marion, SD; Mink, R; Newman, N; O'Neill, J; Vu, JA1
Hasak, MP; Hsu, O; Luong, R; Mayer, D; Orduna, J; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Vinco, S; Zahr, NM1
Aaen, GS; Ashwal, S; Colbert, C; Holshouser, BA; Kido, D; McKenney, M; Sheridan, C1
Arheart, KL; Falcone, S; Gold, S; Govind, V; Harris, L; Jagid, J; Kaliannan, K; Maudsley, AA; Saigal, G1
Barker, PB; Bertrand, M; Degoankar, M; Horská, A; Munro, CA; Pham, D; Rao, V; Rosenberg, P; Ward, J; Yousem, DM1
Lazzarino, G; Signoretti, S; Tavazzi, B; Vagnozzi, R1
Atkinson, JH; Clifford, D; Collier, AC; Ellis, RJ; Fennema-Notestine, C; Franklin, D; Gelman, B; Grant, I; Heaton, R; Jernigan, T; Lin, K; Marra, C; McArthur, J; McCutchan, A; Morgello, S; Simpson, D; Taylor, MJ1
Deng-Bryant, Y; Harris, NG; Hovda, DA; Prins, ML1
Amorini, AM; Barrios, L; Di Pietro, V; Marmarou, A; Marmarou, CR; Pascual, JM; Prieto, R; Tavazzi, B; Taya, K1
Gay, M; Hallett, M; Horovitz, S; Johnson, B; Neuberger, T; Sebastianelli, W; Slobounov, S; Zhang, K1
Geng, ZJ; Li, H; Li, JP; Lin, CG; Liu, XW; Mo, YX; Xie, CM; Zhang, R1
Akhadov, TA; Lukovenkov, AV; Petryaykin, AV; Semenova, NA; Sidorin, SS; Varfolomeev, SD1
Babb, JS; Gonen, O; Grossman, RI; Kirov, II; Lui, YW; Tal, A1
Galloway, M; Ghoddoussi, F; Kepsel, A; Sajja, VS; VandeVord, P1
Brinker, T; Samii, M; Schuhmann, MU; Skardelly, M; Stiller, D; Thomas, S1
Beaumont, A; Bullock, R; Fatouros, P; Hoyle, R; Marmarou, A; Sawauchi, S; Signoretti, S; Young, H1
Andrews, PJ; Easton, VJ; Macmillan, CS; Marshall, I; Wardlaw, JM; Wild, JM1
Albayram, S; Aydin, S; Dashti, SG; Hanci, M; Kuday, C; Uzan, M1
Arlien-Søborg, P; Christensen, PB; Danielsen, ER; Thomsen, C1
Bernarding, J; Brinker, T; Klinge, PM; Samii, A; Samii, M; Schuhmann, MU; Skardelly, M; Stiller, D1
Amorini, AM; Dunbar, J; Lazzarino, G; Marmarou, A; Signoretti, S; Tavazzi, B; Vagnozzi, R1
Chaseling, R; Joy, P; Kemp, A; Parry, L; Rae, C; Shores, A; Waugh, MC1
Ashwal, S; Gross, M; Holshouser, B; Kido, D; Osterdock, R; Serna, T; Tong, K1
Holshouser, BA; Shutter, L; Tong, KA1
Amorini, AM; Cimatti, M; Delfini, R; Lazzarino, G; Marmarou, A; Signoretti, S; Tavazzi, B; Vagnozzi, R1
Brooks, WM; Hunter, JV; Levin, HS; Roberson, G; Swank, PR; Thornton, RJ; Wang, ZJ1
Ball, WS; Care, M; Cecil, KM; Makoroff, KL1
Fauvage, B; Francony, G; Le Bas, JF; Payen, JF1
Choe, BY; Choi, CB; Han, DY; Han, YM; Jeun, SS; Kang, YW; Kim, HY1
Amorini, AM; Cimatti, M; Delfini, R; Donzelli, S; Lazzarino, G; Signoretti, S; Tavazzi, B; Vagnozzi, R1
Amorini, AM; Belli, A; Bellia, F; Kitchen, N; Lazzarino, G; Petzold, A; Russo, S; Sen, J; Signoretti, S; Smith, M; Tavazzi, B; Vagnozzi, R1
Ashwal, S; Ghamsary, M; Holshouser, BA; Oyoyo, U; Saunders, D; Shutter, L; Tong, KA1
Brooks, WM; Jung, RE; Yeo, RA1
Chao, L; Laxer, K; Meyerhoff, DJ; Mueller, S; Sacrey, DT; Schuff, N; Weiner, MW1
Ashwal, S; Babikian, T; Burley, T; Freier, MC; Holshouser, BA; Riggs, ML1
Brooks, WM; Brown, AJ; Campbell, RC; Jung, RE; Phillips, JP; Yeo, RA1
Cimatti, M1
Ashwal, S; Babikian, T; Freier, MC; Gardner-Nichols, J; Holshouser, BA; Tong, KA1
Nakabayashi, M; Suzaki, S; Tomita, H1
Babb, JS; Cohen, BA; Gonen, O; Grossman, RI; Inglese, M; Rusinek, H1
Castillo, M1
Barrios, L; Cerdán, S; López-Larrubia, P; Pascual, JM; Prieto, R; Roda, JM; Solivera, J1
Babb, JS; Fleysher, L; Gonen, O; Grossman, RI; Kirov, I; Silver, JM1
Aygok, GA; Bullock, RM; Fatouros, PP; Marmarou, A; Portella, G; Signoretti, S1
Casey, PA; Fiskum, G; McKenna, MC; Robertson, CL; Saraswati, M1
Danielsen, ER; Michaelis, T; Ross, BD1
Ashwal, S; Bailey, L; Hinshaw, DB; Holshouser, BA; Schell, RM1
Ashwal, S; Auld, KL; Hinshaw, DB; Holshouser, BA; Kahlon, S; Luh, GY; Perkin, RM; Shu, S; Tomasi, LG1
Barbarella, G; Basaglia, N; Boldrini, P; Musi, P; Ricci, R; Trevisan, C1
Cecil, K; Lenkinski, RE; McIntosh, TK; Rubin, Y; Smith, DH; Wehrli, S1
Cecil, KM; Lenkinski, RE; McIntosh, TK; Meaney, DF; Smith, DH1
Bagley, LJ; Cecil, KM; Grossman, RI; Hills, EC; Lenkinski, RE; Mannon, LJ; McIntosh, TK; Sandel, ME; Sinson, GP; Smith, DH1
Cecil, KM; Chen, XH; Gennarelli, TA; Lenkinski, RE; McIntosh, TK; Meaney, DF; Smith, DH1
Amorini, AM; Caruso, I; Di Pierro, D; Fazzina, G; Lazzarino, G; Marmarou, A; Signoretti, S; Tavazzi, B; Vagnozzi, R1
Al-Samsam, RH; Alessandri, B; Bullock, R1
Blamire, AM; Cadoux-Hudson, TA; Garnett, MR; Rajagopalan, B; Styles, P1
Barlow, MA; Brooks, WM; Friedman, SD; Jung, RE; Petropoulos, H; Sibbitt, WL; Stidley, CA; Weers, DC; Yeo, RA1
Blamire, AM; Cadoux-Hudson, TA; Corkill, RG; Garnett, MR; Rajagopalan, B; Styles, P1
al-Samsam, R; Alessandri, B; Bullock, RM; Corwin, F; Fatouros, P; Young, HF1
Bagley, LJ; Cecil, KM; Grossman, RI; Lenkinski, RE; McGowan, JC; McIntosh, TK; Sinson, G; Torchia, M1
Blamire, AM; Cadoux-Hudson, TA; Corkill, RG; Garnett, MR; Manners, DN; Rajagopalan, B; Styles, P; Young, JD1
Arfai, N; Feeney, DM; Gasparovic, C; Smid, N1
Bard, C; Boulanger, Y; Khiat, A; Lacroix, A; Yared, Z1
Babb, JS; Fowble, BL; Gonen, O; Li, BS; Movsas, B; Nicolaou, N1
Chang, LH; Cohen, Y; James, TL; Litt, L; Nishimura, MC; Pitts, LH; Sanada, T; Weinstein, PR1
Faden, AI; McIntosh, TK; Vink, R1

Reviews

7 review(s) available for n-acetylaspartic acid and Brain Injuries

ArticleYear
A systematic review of Magnetic Resonance Imaging and Spectroscopy in brain injury after drowning.
    Brain injury, 2009, Volume: 23, Issue:9

    Topics: Aspartic Acid; Brain Injuries; Child; Child, Preschool; Drowning; Female; Humans; Hypoxia, Brain; Infant; Lactic Acid; Magnetic Resonance Spectroscopy; Male; United States

2009
Biochemical and neurochemical sequelae following mild traumatic brain injury: summary of experimental data and clinical implications.
    Neurosurgical focus, 2010, Volume: 29, Issue:5

    Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Diffuse Axonal Injury; Disease Models, Animal; Humans; Magnetic Resonance Spectroscopy; Oxidative Stress; Rats

2010
[Contribution of magnetic resonance spectroscopy in predicting severity and outcome in traumatic brain injury].
    Annales francaises d'anesthesie et de reanimation, 2005, Volume: 24, Issue:5

    Topics: Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Brain Injuries; Choline; Craniocerebral Trauma; Energy Metabolism; Glasgow Outcome Scale; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Animal; Prognosis; Rats; Wounds, Nonpenetrating

2005
NAA and higher cognitive function in humans.
    Advances in experimental medicine and biology, 2006, Volume: 576

    Topics: Aspartic Acid; Brain; Brain Injuries; Cognition; Humans; Magnetic Resonance Spectroscopy

2006
N-acetylaspartate as a marker of neuronal injury in neurodegenerative disease.
    Advances in experimental medicine and biology, 2006, Volume: 576

    Topics: Aging; Alcoholism; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Cocaine; Creatine; Epilepsy; Ethanol; HIV Infections; Humans; Magnetic Resonance Imaging; Neurodegenerative Diseases; Neurons; Stress Disorders, Post-Traumatic

2006
Susceptibility-weighted imaging and proton magnetic resonance spectroscopy in assessment of outcome after pediatric traumatic brain injury.
    Archives of physical medicine and rehabilitation, 2006, Volume: 87, Issue:12 Suppl 2

    Topics: Aspartic Acid; Axons; Brain Injuries; Child; Choline; Creatine; Humans; Imaging, Three-Dimensional; Injury Severity Score; Intracranial Hemorrhages; Magnetic Resonance Imaging; Neuropsychological Tests; Outcome Assessment, Health Care

2006
Whole-brain N-acetylaspartate: a marker of the severity of mild head trauma.
    AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:5

    Topics: Aspartic Acid; Biomarkers; Brain Injuries; Humans; Magnetic Resonance Spectroscopy; Trauma Severity Indices

2007

Trials

5 trial(s) available for n-acetylaspartic acid and Brain Injuries

ArticleYear
An experimental study on acute brain radiation injury: dynamic changes in proton magnetic resonance spectroscopy and the correlation with histopathology.
    European journal of radiology, 2012, Volume: 81, Issue:11

    Topics: Animals; Aspartic Acid; Brain Injuries; Choline; Magnetic Resonance Spectroscopy; Protons; Rabbits; Radiation Injuries, Experimental; Statistics as Topic

2012
Proton MR spectroscopy and MRI-volumetry in mild traumatic brain injury.
    AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:5

    Topics: Adult; Age Factors; Aspartic Acid; Atrophy; Axons; Brain; Brain Injuries; Female; Glasgow Coma Scale; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Protons

2007
Assessment of mitochondrial impairment in traumatic brain injury using high-resolution proton magnetic resonance spectroscopy.
    Journal of neurosurgery, 2008, Volume: 108, Issue:1

    Topics: Adolescent; Adult; Aspartic Acid; Brain Injuries; Choline; Creatine; Female; Follow-Up Studies; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondrial Diseases; Outcome Assessment, Health Care; Predictive Value of Tests; Time Factors

2008
Evidence for cellular damage in normal-appearing white matter correlates with injury severity in patients following traumatic brain injury: A magnetic resonance spectroscopy study.
    Brain : a journal of neurology, 2000, Volume: 123 ( Pt 7)

    Topics: Adolescent; Adult; Aged; Amnesia; Aspartic Acid; Axons; Brain Chemistry; Brain Injuries; Cerebral Cortex; Choline; Creatine; Female; Glasgow Coma Scale; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged

2000
Early proton magnetic resonance spectroscopy in normal-appearing brain correlates with outcome in patients following traumatic brain injury.
    Brain : a journal of neurology, 2000, Volume: 123 ( Pt 10)

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Chemistry; Brain Injuries; Choline; Creatine; Disability Evaluation; Female; Glasgow Outcome Scale; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Protons; Recovery of Function

2000

Other Studies

77 other study(ies) available for n-acetylaspartic acid and Brain Injuries

ArticleYear
Hippocampal changes in inflammasomes, apoptosis, and MEMRI after radiation-induced brain injury in juvenile rats.
    Radiation oncology (London, England), 2020, Apr-10, Volume: 15, Issue:1

    Topics: Animals; Apoptosis; Aspartic Acid; Brain Injuries; Caspases; Creatine; Hippocampus; Inflammasomes; Magnetic Resonance Imaging; Male; Manganese Compounds; Radiation Dosage; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley

2020
Third Trimester Cerebellar Metabolite Concentrations are Decreased in Very Premature Infants with Structural Brain Injury.
    Scientific reports, 2019, 02-04, Volume: 9, Issue:1

    Topics: Aspartic Acid; Brain; Brain Injuries; Cerebellum; Choline; Creatine; Female; Gestational Age; Gray Matter; Humans; Infant; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Pregnancy; Pregnancy Trimester, Third; Premature Birth; Proton Magnetic Resonance Spectroscopy

2019
Metabolic changes in patients with aneurysmal subarachnoid hemorrhage apart from perfusion deficits: neuronal mitochondrial injury?
    AJNR. American journal of neuroradiology, 2013, Volume: 34, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Cerebrovascular Disorders; Female; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondria; Neurons; Protons; Subarachnoid Hemorrhage

2013
Impact of methamphetamine on regional metabolism and cerebral blood flow after traumatic brain injury.
    Neurocritical care, 2013, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Amphetamine-Related Disorders; Aspartic Acid; Brain; Brain Injuries; Central Nervous System Stimulants; Cerebrovascular Circulation; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Methamphetamine; Middle Aged; Perfusion Imaging; Prospective Studies; Young Adult

2013
MRSI of the medial temporal lobe at 7 T in explosive blast mild traumatic brain injury.
    Magnetic resonance in medicine, 2014, Volume: 71, Issue:4

    Topics: Adult; Aspartic Acid; Biomarkers; Blast Injuries; Brain Injuries; Choline; Creatine; Explosions; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Military Personnel; Molecular Imaging; Reproducibility of Results; Sensitivity and Specificity; Temporal Lobe; Tissue Distribution; United States

2014
Clinical correlations of proton magnetic resonance spectroscopy findings in acute phase after mild traumatic brain injury.
    Brain injury, 2014, Volume: 28, Issue:3

    Topics: Adult; Aspartic Acid; Biomarkers; Brain Injuries; Cognition Disorders; Creatine; Female; Frontal Lobe; Glasgow Coma Scale; Humans; Male; Middle Aged; Neuropsychological Tests; Proton Magnetic Resonance Spectroscopy; Sensitivity and Specificity

2014
Myoinositol and glutamate complex neurometabolite abnormality after mild traumatic brain injury.
    Neurology, 2014, Feb-11, Volume: 82, Issue:6

    Topics: Adult; Aspartic Acid; Brain Injuries; Case-Control Studies; Caudate Nucleus; Choline; Corpus Striatum; Creatine; Female; Globus Pallidus; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Fibers, Unmyelinated; Putamen; Thalamus; Young Adult

2014
The molecular mechanisms affecting N-acetylaspartate homeostasis following experimental graded traumatic brain injury.
    Molecular medicine (Cambridge, Mass.), 2014, Mar-24, Volume: 20

    Topics: Acetyltransferases; Adenosine Diphosphate; Adenosine Triphosphate; Amidohydrolases; Animals; Aspartic Acid; Brain; Brain Injuries; Disease Models, Animal; Male; Mitochondria; Phosphorylation; Rats; Rats, Wistar

2014
Magnetic resonance spectroscopic imaging of brain injury after nasopharyngeal cancer radiation in early delayed reaction.
    Genetics and molecular research : GMR, 2014, Aug-29, Volume: 13, Issue:3

    Topics: Adult; Aspartic Acid; Brain Injuries; Choline; Creatine; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nasopharyngeal Neoplasms; Prognosis; Radiation Injuries; Radiotherapy; Time Factors

2014
Evaluation of impact-induced traumatic brain injury in the Göttingen Minipig using two input modes.
    Traffic injury prevention, 2014, Volume: 15 Suppl 1

    Topics: Animals; Aspartic Acid; Brain Injuries; Dipeptides; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Swine; Swine, Miniature

2014
N-acetyl-aspartate levels correlate with intra-axonal compartment parameters from diffusion MRI.
    NeuroImage, 2015, Volume: 118

    Topics: Adult; Aspartic Acid; Axons; Brain; Brain Injuries; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Female; Humans; Inositol; Male; Models, Neurological; Proton Magnetic Resonance Spectroscopy; White Matter

2015
Neuroprotective efficacy of decompressive craniectomy after controlled cortical impact injury in rats: An MRI study.
    Brain research, 2015, Oct-05, Volume: 1622

    Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Choline; Creatine; Decompressive Craniectomy; Disease Models, Animal; Lactic Acid; Longitudinal Studies; Magnetic Resonance Imaging; Male; Proton Magnetic Resonance Spectroscopy; Random Allocation; Rats, Sprague-Dawley; Treatment Outcome

2015
Methamphetamine Induces Anhedonic-Like Behavior and Impairs Frontal Cortical Energetics in Mice.
    CNS neuroscience & therapeutics, 2017, Volume: 23, Issue:2

    Topics: Anhedonia; Animals; Aspartic Acid; Brain Injuries; Central Nervous System Stimulants; Cerebral Cortex; Disease Models, Animal; Exploratory Behavior; Food Preferences; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Glutamic Acid; Grooming; Male; Maze Learning; Methamphetamine; Mice; Mice, Inbred C57BL; Motor Activity

2017
When are metabolic ratios superior to absolute quantification? A statistical analysis.
    NMR in biomedicine, 2017, Volume: 30, Issue:7

    Topics: Adult; Algorithms; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Data Interpretation, Statistical; Female; Humans; Magnetic Resonance Spectroscopy; Male; Metabolic Flux Analysis; Middle Aged; Reproducibility of Results; Sensitivity and Specificity

2017
Distinct MRI pattern in lesional and perilesional area after traumatic brain injury in rat--11 months follow-up.
    Experimental neurology, 2009, Volume: 215, Issue:1

    Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Injuries; Creatine; Diffusion Magnetic Resonance Imaging; Dipeptides; Disease Models, Animal; Follow-Up Studies; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Statistics, Nonparametric; Time Factors

2009
Brain injury in glutaric aciduria type I: the value of functional techniques in magnetic resonance imaging.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2009, Volume: 13, Issue:6

    Topics: Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Brain; Brain Injuries; Brain Mapping; Creatine; Glutarates; Glutaryl-CoA Dehydrogenase; Humans; Infant; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Retrospective Studies

2009
Assessment of mitochondrial impairment and cerebral blood flow in severe brain injured patients.
    Acta neurochirurgica. Supplement, 2008, Volume: 102

    Topics: Aspartic Acid; Blood Flow Velocity; Brain Injuries; Cerebrovascular Circulation; Diffusion Magnetic Resonance Imaging; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Mitochondrial Diseases; Protons; Regional Blood Flow

2008
Proton spectroscopy in patients with post-traumatic headache attributed to mild head injury.
    Headache, 2009, Volume: 49, Issue:9

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Injuries; Brain Mapping; Cell Membrane; Choline; Chronic Disease; Craniocerebral Trauma; Female; Headache; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Severity of Illness Index; Young Adult

2009
Transient alterations of creatine, creatine phosphate, N-acetylaspartate and high-energy phosphates after mild traumatic brain injury in the rat.
    Molecular and cellular biochemistry, 2010, Volume: 333, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Brain Chemistry; Brain Injuries; Creatine; Energy Metabolism; Kinetics; Phosphates; Phosphocreatine; Rats

2010
Temporal and regional changes after focal traumatic brain injury.
    Journal of neurotrauma, 2010, Volume: 27, Issue:1

    Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Brain Mapping; Cerebral Cortex; Choline; Creatine; Diffusion; Disease Models, Animal; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Time Factors

2010
Metabolic acetate therapy for the treatment of traumatic brain injury.
    Journal of neurotrauma, 2010, Volume: 27, Issue:1

    Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Animals; Aspartic Acid; Brain; Brain Injuries; Disease Models, Animal; Energy Metabolism; Lipid Metabolism; Male; Membrane Lipids; Myelin Sheath; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Treatment Outcome; Triacetin; Up-Regulation

2010
Evaluation of the late effects of CNS prophylactic treatment in childhood acute lymphoblastic leukemia (ALL) using magnetic resonance spectroscopy.
    Acta neurochirurgica. Supplement, 2010, Volume: 106

    Topics: Adolescent; Aspartic Acid; Brain Injuries; Case-Control Studies; Child; Child, Preschool; Choline; Cranial Irradiation; Creatine; Drug Administration Routes; Drug Therapy; Female; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tissue Distribution

2010
Metabolic levels in the corpus callosum and their structural and behavioral correlates after moderate to severe pediatric TBI.
    Journal of neurotrauma, 2010, Volume: 27, Issue:3

    Topics: Adolescent; Age Factors; Aging; Anisotropy; Aspartic Acid; Axons; Biomarkers; Brain Injuries; Child; Choline; Cognition Disorders; Corpus Callosum; Diffuse Axonal Injury; Diffusion Tensor Imaging; Female; Humans; Magnetic Resonance Spectroscopy; Male; Wallerian Degeneration

2010
Brain injury and recovery following binge ethanol: evidence from in vivo magnetic resonance spectroscopy.
    Biological psychiatry, 2010, May-01, Volume: 67, Issue:9

    Topics: Alcoholism; Analysis of Variance; Animals; Aspartic Acid; Body Weight; Brain Injuries; Brain Mapping; Central Nervous System Depressants; Cerebral Ventricles; Choline; Creatine; Ethanol; Hippocampus; Magnetic Resonance Spectroscopy; Male; Oxygen; Rats; Rats, Wistar; Recovery of Function; Statistics as Topic; Taurine; Time Factors

2010
Magnetic resonance spectroscopy predicts outcomes for children with nonaccidental trauma.
    Pediatrics, 2010, Volume: 125, Issue:2

    Topics: Aspartic Acid; Brain Injuries; Cerebral Infarction; Child; Child, Preschool; Female; Glasgow Coma Scale; Humans; Lactates; Logistic Models; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Prognosis

2010
Whole-brain proton MR spectroscopic imaging of mild-to-moderate traumatic brain injury and correlation with neuropsychological deficits.
    Journal of neurotrauma, 2010, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Cognition Disorders; Creatine; Diffuse Axonal Injury; Disability Evaluation; Female; Frontal Lobe; Glasgow Coma Scale; Humans; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Neuropsychological Tests; Wallerian Degeneration; Young Adult

2010
Neuroanatomical correlates of depression in post traumatic brain injury: preliminary results of a pilot study.
    The Journal of neuropsychiatry and clinical neurosciences, 2010,Spring, Volume: 22, Issue:2

    Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Brain Injuries; Case-Control Studies; Choline; Cognition Disorders; Creatine; Depressive Disorder, Major; Frontal Lobe; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Middle Aged; Neuropsychological Tests; Organ Size; Pilot Projects; Time Factors

2010
Effects of traumatic brain injury on cognitive functioning and cerebral metabolites in HIV-infected individuals.
    Journal of clinical and experimental neuropsychology, 2011, Volume: 33, Issue:3

    Topics: Adult; Aspartic Acid; Brain Injuries; Cognition Disorders; Depression; Executive Function; Female; HIV Infections; Humans; Magnetic Resonance Spectroscopy; Male; Memory, Short-Term; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Substance-Related Disorders

2011
Ketogenic diet prevents alterations in brain metabolism in young but not adult rats after traumatic brain injury.
    Journal of neurotrauma, 2011, Volume: 28, Issue:9

    Topics: 3-Hydroxybutyric Acid; Age Factors; Amino Acids; Animals; Aspartic Acid; Brain; Brain Injuries; Diet, Ketogenic; Energy Metabolism; Magnetic Resonance Spectroscopy; Rats

2011
Brain energy depletion in a rodent model of diffuse traumatic brain injury is not prevented with administration of sodium lactate.
    Brain research, 2011, Aug-02, Volume: 1404

    Topics: Adenosine Triphosphate; Animals; Ascorbic Acid; Aspartic Acid; Blood Gas Analysis; Blood Pressure; Brain Chemistry; Brain Injuries; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Energy Metabolism; Glutathione; Male; Models, Biological; NAD; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sodium Lactate

2011
Metabolic alterations in corpus callosum may compromise brain functional connectivity in MTBI patients: an 1H-MRS study.
    Neuroscience letters, 2012, Feb-10, Volume: 509, Issue:1

    Topics: Aspartic Acid; Brain Injuries; Case-Control Studies; Choline; Corpus Callosum; Creatine; Female; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Young Adult

2012
Metabolic dysfunction and relationship in human frontoparietal cortex in severe traumatic brain injury: single-voxel (1)H magnetic resonance spectroscopy study.
    Biochemistry. Biokhimiia, 2012, Volume: 77, Issue:4

    Topics: Adolescent; Aspartic Acid; Brain; Brain Injuries; Cerebral Cortex; Child; Child, Preschool; Choline; Creatine; Female; Humans; Inositol; Magnetic Resonance Imaging; Male; Radiography

2012
Diffuse axonal injury in mild traumatic brain injury: a 3D multivoxel proton MR spectroscopy study.
    Journal of neurology, 2013, Volume: 260, Issue:1

    Topics: Adolescent; Adult; Aspartic Acid; Brain Injuries; Brain Mapping; Choline; Creatine; Diffuse Axonal Injury; Female; Glasgow Coma Scale; Humans; Imaging, Three-Dimensional; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Young Adult

2013
Effects of blast-induced neurotrauma on the nucleus accumbens.
    Journal of neuroscience research, 2013, Volume: 91, Issue:4

    Topics: Animals; Apoptosis; Aspartic Acid; bcl-2-Associated X Protein; Blast Injuries; Brain Injuries; Caspase 3; Glial Fibrillary Acidic Protein; Inflammation; Male; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Serotonin

2013
Long-time in-vivo metabolic monitoring following experimental brain contusion using proton magnetic resonance spectroscopy.
    Acta neurochirurgica. Supplement, 2002, Volume: 81

    Topics: Animals; Aspartic Acid; Basal Ganglia; Biomarkers; Brain; Brain Injuries; Disease Models, Animal; Functional Laterality; Glutamic Acid; Hippocampus; Lactates; Magnetic Resonance Imaging; Male; Monitoring, Physiologic; Phosphocreatine; Rats; Rats, Sprague-Dawley; Reference Values; Taurine; Time Factors

2002
Application of chemical shift imaging for measurement of NAA in head injured patients.
    Acta neurochirurgica. Supplement, 2002, Volume: 81

    Topics: Aspartic Acid; Biomarkers; Brain Injuries; Choline; Creatinine; Humans; Magnetic Resonance Imaging; Monitoring, Intraoperative; Neurochemistry; Reference Values; Time Factors; Treatment Outcome

2002
Traumatic brain injury and subarachnoid hemorrhage: in vivo occult pathology demonstrated by magnetic resonance spectroscopy may not be "ischaemic". A primary study and review of the literature.
    Acta neurochirurgica, 2002, Volume: 144, Issue:9

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Injuries; Brain Ischemia; Child; Choline; Creatine; Critical Care; Diffuse Axonal Injury; Energy Metabolism; Female; Follow-Up Studies; Glasgow Coma Scale; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Subarachnoid Hemorrhage; Tomography, X-Ray Computed

2002
Thalamic proton magnetic resonance spectroscopy in vegetative state induced by traumatic brain injury.
    Journal of neurology, neurosurgery, and psychiatry, 2003, Volume: 74, Issue:1

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Child; Choline; Creatine; Diffuse Axonal Injury; Female; Glasgow Coma Scale; Glasgow Outcome Scale; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Persistent Vegetative State; Predictive Value of Tests; Protons; Recovery of Function; Reference Values; Thalamus

2003
Axonal recovery after severe traumatic brain injury demonstrated in vivo by 1H MR spectroscopy.
    Neuroradiology, 2003, Volume: 45, Issue:10

    Topics: Adult; Aspartic Acid; Axons; Brain; Brain Injuries; Cognition; Female; Humans; Magnetic Resonance Spectroscopy; Protons; Recovery of Function; Trauma Severity Indices

2003
Metabolic changes in the vicinity of brain contusions: a proton magnetic resonance spectroscopy and histology study.
    Journal of neurotrauma, 2003, Volume: 20, Issue:8

    Topics: Animals; Aspartic Acid; Biomarkers; Brain Injuries; Choline; Creatine; Functional Laterality; Glutamic Acid; Immunohistochemistry; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Protons; Rats; Rats, Sprague-Dawley; Taurine; Time Factors

2003
The protective effect of cyclosporin A upon N-acetylaspartate and mitochondrial dysfunction following experimental diffuse traumatic brain injury.
    Journal of neurotrauma, 2004, Volume: 21, Issue:9

    Topics: Animals; Aspartic Acid; Brain Injuries; Cyclosporine; Drug Administration Schedule; Infusions, Intravenous; Injections, Spinal; Male; Mitochondria; Neuroprotective Agents; Rats; Rats, Sprague-Dawley

2004
An investigation of neuronal integrity in severe paediatric traumatic brain injury.
    Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence, 2004, Volume: 10, Issue:4

    Topics: Adolescent; Age Factors; Aspartic Acid; Brain Injuries; Child; Choline; Cognition Disorders; Creatine; Female; Frontal Lobe; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Neuropsychological Tests; Reaction Time; Reference Values; Severity of Illness Index; Statistics, Nonparametric

2004
Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury.
    Journal of neurotrauma, 2004, Volume: 21, Issue:11

    Topics: Adolescent; Age Factors; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Coma; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Nerve Degeneration; Occipital Lobe; Parietal Lobe; Predictive Value of Tests; Recovery of Function; Up-Regulation

2004
Proton MRS in acute traumatic brain injury: role for glutamate/glutamine and choline for outcome prediction.
    Journal of neurotrauma, 2004, Volume: 21, Issue:12

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Cerebral Cortex; Choline; Creatinine; Evoked Potentials, Somatosensory; Female; Follow-Up Studies; Glasgow Outcome Scale; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Time Factors

2004
Cerebral oxidative stress and depression of energy metabolism correlate with severity of diffuse brain injury in rats.
    Neurosurgery, 2005, Volume: 56, Issue:3

    Topics: Animals; Ascorbic Acid; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Injuries; Chromatography, High Pressure Liquid; Energy Metabolism; Head Injuries, Closed; Hypotension; Hypoxia; Male; Malondialdehyde; NAD; NADP; Nucleosides; Oxidative Stress; Phosphates; Purines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2005
Late proton MR spectroscopy in children after traumatic brain injury: correlation with cognitive outcomes.
    AJNR. American journal of neuroradiology, 2005, Volume: 26, Issue:3

    Topics: Adolescent; Aspartic Acid; Brain; Brain Injuries; Case-Control Studies; Child; Choline; Cognition; Creatine; Dominance, Cerebral; Female; Frontal Lobe; Humans; Magnetic Resonance Spectroscopy; Male; Mathematics; Mental Processes; Osmolar Concentration; Wounds, Nonpenetrating

2005
Elevated lactate as an early marker of brain injury in inflicted traumatic brain injury.
    Pediatric radiology, 2005, Volume: 35, Issue:7

    Topics: Aspartic Acid; Brain Chemistry; Brain Injuries; Critical Care; Female; Fractures, Bone; Frontal Lobe; Glasgow Outcome Scale; Humans; Hypoxia-Ischemia, Brain; Infant; Infant, Newborn; Lactic Acid; Length of Stay; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurologic Examination; Occipital Lobe; Parietal Lobe; Prospective Studies; Retinal Hemorrhage; Seizures

2005
In vivo 1H MR spectroscopic findings in traumatic contusion of ICR mouse brain induced by fluid percussion injury.
    European journal of radiology, 2005, Volume: 55, Issue:1

    Topics: Animals; Aspartic Acid; Brain Injuries; Choline; Creatine; Magnetic Resonance Spectroscopy; Male; Mice; Percussion; Signal Processing, Computer-Assisted

2005
Hypothesis of the postconcussive vulnerable brain: experimental evidence of its metabolic occurrence.
    Neurosurgery, 2005, Volume: 57, Issue:1

    Topics: Adenosine Triphosphate; Animals; Apyrase; Aspartic Acid; Blood Gas Analysis; Brain; Brain Injuries; Chromatography, High Pressure Liquid; Disease Models, Animal; Energy Metabolism; Male; Rats; Rats, Wistar; Time Factors

2005
Extracellular N-acetylaspartate depletion in traumatic brain injury.
    Journal of neurochemistry, 2006, Volume: 96, Issue:3

    Topics: Adult; Aged; Aspartic Acid; Brain Chemistry; Brain Injuries; Extracellular Space; Humans; Magnetic Resonance Spectroscopy; Microdialysis; Middle Aged; Postmortem Changes; Time Factors

2006
Prospective longitudinal proton magnetic resonance spectroscopic imaging in adult traumatic brain injury.
    Journal of magnetic resonance imaging : JMRI, 2006, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Case-Control Studies; Corpus Callosum; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurology; Protons

2006
MR spectroscopy: predicting long-term neuropsychological outcome following pediatric TBI.
    Journal of magnetic resonance imaging : JMRI, 2006, Volume: 24, Issue:4

    Topics: Adolescent; Aspartic Acid; Brain Injuries; Child; Child, Preschool; Creatine; Female; Glutamic Acid; Glutamine; Humans; Infant; Inositol; Linear Models; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Predictive Value of Tests; Recovery of Function; Statistics, Nonparametric

2006
Magnetic resonance spectroscopy detects brain injury and predicts cognitive functioning in children with brain injuries.
    Journal of neurotrauma, 2006, Volume: 23, Issue:10

    Topics: Adolescent; Aspartic Acid; Brain Injuries; Case-Control Studies; Child; Choline; Cognition; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Memory; Motor Activity

2006
Assessment of metabolic cerebral damage using proton magnetic resonance spectroscopy in mild traumatic brain injury.
    Journal of neurosurgical sciences, 2006, Volume: 50, Issue:4

    Topics: Adult; Aspartic Acid; Boxing; Brain; Brain Injuries; Humans; Magnetic Resonance Spectroscopy; Male

2006
Neural injury and recovery near cortical contusions: a clinical magnetic resonance spectroscopy study.
    Journal of neurosurgery, 2007, Volume: 106, Issue:3

    Topics: Adolescent; Adult; Aspartic Acid; Brain Injuries; Case-Control Studies; Choline; Creatine; Female; Glasgow Coma Scale; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Middle Aged; Time Factors

2007
Time course of early metabolic changes following diffuse traumatic brain injury in rats as detected by (1)H NMR spectroscopy.
    Journal of neurotrauma, 2007, Volume: 24, Issue:6

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Injuries; Creatine; Diffuse Axonal Injury; Disease Models, Animal; Disease Progression; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Time Factors; Up-Regulation; Water-Electrolyte Balance

2007
Characterizing 'mild' in traumatic brain injury with proton MR spectroscopy in the thalamus: Initial findings.
    Brain injury, 2007, Volume: 21, Issue:11

    Topics: Adult; Aspartic Acid; Brain Injuries; Choline; Creatine; Female; Glasgow Coma Scale; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Thalamus; Trauma Severity Indices

2007
Early and sustained alterations in cerebral metabolism after traumatic brain injury in immature rats.
    Journal of neurotrauma, 2008, Volume: 25, Issue:6

    Topics: Aging; Alanine; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Cell Respiration; Choline; Creatine; Disease Progression; Energy Metabolism; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mitochondria; Nerve Degeneration; Oxidative Phosphorylation; Rats; Rats, Sprague-Dawley; Time Factors

2008
Three methods of calibration in quantitative proton MR spectroscopy.
    Journal of magnetic resonance. Series B, 1995, Volume: 106, Issue:3

    Topics: Adult; Aspartic Acid; Body Water; Brain; Brain Chemistry; Brain Injuries; Calibration; Choline; Creatine; Hepatic Encephalopathy; Humans; Inositol; Magnetic Resonance Spectroscopy; Models, Structural

1995
Proton magnetic resonance spectroscopy in the evaluation of children with congenital heart disease and acute central nervous system injury.
    The Journal of thoracic and cardiovascular surgery, 1996, Volume: 112, Issue:2

    Topics: Aspartic Acid; Brain; Brain Injuries; Cardiopulmonary Bypass; Case-Control Studies; Child, Preschool; Choline; Coma; Creatine; Follow-Up Studies; Forecasting; Glasgow Coma Scale; Heart Arrest; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Lactates; Magnetic Resonance Spectroscopy; Neurologic Examination; Patient Discharge; Phosphocreatine; Protons; Treatment Outcome

1996
Proton MR spectroscopy after acute central nervous system injury: outcome prediction in neonates, infants, and children.
    Radiology, 1997, Volume: 202, Issue:2

    Topics: Adolescent; Aspartic Acid; Brain; Brain Diseases; Brain Injuries; Child; Choline; Discriminant Analysis; Female; Humans; Infant; Infant, Newborn; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Predictive Value of Tests; Prognosis

1997
Localised proton MR spectroscopy of brain metabolism changes in vegetative patients.
    Neuroradiology, 1997, Volume: 39, Issue:5

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Persistent Vegetative State; Prognosis; Time Factors

1997
High-resolution 1H NMR spectroscopy following experimental brain trauma.
    Journal of neurotrauma, 1997, Volume: 14, Issue:7

    Topics: Animals; Aspartic Acid; Brain Injuries; Disease Models, Animal; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Time Factors

1997
High-field proton magnetic resonance spectroscopy of a swine model for axonal injury.
    Journal of neurochemistry, 1998, Volume: 70, Issue:5

    Topics: Animals; Aspartic Acid; Axons; Brain; Brain Injuries; Creatine; Disease Models, Animal; Female; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Sensitivity and Specificity; Swine; Swine, Miniature

1998
Proton magnetic resonance spectroscopy for detection of axonal injury in the splenium of the corpus callosum of brain-injured patients.
    Journal of neurosurgery, 1998, Volume: 88, Issue:5

    Topics: Acceleration; Accidents, Traffic; Adult; Aged; Aspartic Acid; Axons; Brain Concussion; Brain Diseases; Brain Injuries; Cell Survival; Cerebral Hemorrhage; Cognition Disorders; Corpus Callosum; Creatine; Deceleration; Female; Hematoma, Epidural, Cranial; Hematoma, Subdural; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Protons; Rotation; Stress, Mechanical

1998
Magnetic resonance spectroscopy of diffuse brain trauma in the pig.
    Journal of neurotrauma, 1998, Volume: 15, Issue:9

    Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Axons; Behavior, Animal; Brain Chemistry; Brain Injuries; Female; Lactic Acid; Magnesium; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Phosphorus; Protons; Swine; Swine, Miniature

1998
Ion-pairing high-performance liquid chromatographic method for the detection of N-acetylaspartate and N-acetylglutamate in cerebral tissue extracts.
    Analytical biochemistry, 2000, Jan-01, Volume: 277, Issue:1

    Topics: Animals; Aspartic Acid; Brain Chemistry; Brain Injuries; Chromatography, High Pressure Liquid; Glutamates; Male; Rats; Rats, Wistar; Tissue Extracts

2000
Extracellular N-acetyl-aspartate as a biochemical marker of the severity of neuronal damage following experimental acute traumatic brain injury.
    Journal of neurotrauma, 2000, Volume: 17, Issue:1

    Topics: Animals; Aspartic Acid; Biomarkers; Blood Gas Analysis; Blood Pressure; Brain; Brain Chemistry; Brain Injuries; Chromatography, High Pressure Liquid; Disease Models, Animal; Extracellular Space; Hydrogen-Ion Concentration; Hypotension; Hypoxia, Brain; Magnetic Resonance Imaging; Male; Neurons; Rats; Rats, Sprague-Dawley

2000
Metabolic and cognitive response to human traumatic brain injury: a quantitative proton magnetic resonance study.
    Journal of neurotrauma, 2000, Volume: 17, Issue:8

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Choline; Cognition Disorders; Creatinine; Cross-Sectional Studies; Female; Humans; Inositol; Logistic Models; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Protons; Statistics, Nonparametric

2000
Acute and late changes in N-acetyl-aspartate following diffuse axonal injury in rats: an MRI spectroscopy and microdialysis study.
    Neurological research, 2000, Volume: 22, Issue:7

    Topics: Animals; Aspartic Acid; Biomarkers; Brain Injuries; Diffuse Axonal Injury; Magnetic Resonance Imaging; Male; Microdialysis; Rats; Rats, Sprague-Dawley

2000
Magnetization transfer imaging and proton MR spectroscopy in the evaluation of axonal injury: correlation with clinical outcome after traumatic brain injury.
    AJNR. American journal of neuroradiology, 2001, Volume: 22, Issue:1

    Topics: Aspartic Acid; Axons; Biomarkers; Brain; Brain Injuries; Brain Stem; Corpus Callosum; Creatine; Glasgow Coma Scale; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Time Factors

2001
Altered cellular metabolism following traumatic brain injury: a magnetic resonance spectroscopy study.
    Journal of neurotrauma, 2001, Volume: 18, Issue:3

    Topics: Adenosine Triphosphate; Adolescent; Adult; Aspartic Acid; Brain; Brain Injuries; Choline; Creatine; Female; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphates; Phosphocreatine

2001
Decrease and recovery of N-acetylaspartate/creatine in rat brain remote from focal injury.
    Journal of neurotrauma, 2001, Volume: 18, Issue:3

    Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Creatine; Magnetic Resonance Spectroscopy; Occipital Lobe; Rats; Rats, Sprague-Dawley

2001
Long-term brain metabolic alterations in exogenous Cushing's syndrome as monitored by proton magnetic resonance spectroscopy.
    Brain research, 2001, Aug-24, Volume: 911, Issue:2

    Topics: Adult; Aspartic Acid; Brain; Brain Diseases, Metabolic; Brain Injuries; Cell Membrane; Choline; Creatine; Cushing Syndrome; Drug Administration Schedule; Energy Metabolism; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Degeneration; Neurons; Prednisone

2001
Quantifying radiation therapy-induced brain injury with whole-brain proton MR spectroscopy: initial observations.
    Radiology, 2001, Volume: 221, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Brain Injuries; Female; Humans; Magnetic Resonance Spectroscopy; Male; Mental Status Schedule; Middle Aged; Radiation Injuries

2001
Surface coil spectroscopic imaging: time and spatial evolution of lactate production following fluid percussion brain injury.
    Magnetic resonance in medicine, 1991, Volume: 17, Issue:1

    Topics: Animals; Aspartic Acid; Brain Concussion; Brain Edema; Brain Injuries; Deuterium; Fourier Analysis; Lactates; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains; Time Factors

1991
Nonedited 1H NMR lactate/n-acetyl aspartate ratios and the in vivo determination of lactate concentration in brain.
    Magnetic resonance in medicine, 1988, Volume: 7, Issue:1

    Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Lactates; Magnetic Resonance Spectroscopy; Rats; Rats, Inbred Strains

1988