n-acetylaspartic acid has been researched along with Bipolar Disorder in 96 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (4.17) | 18.2507 |
| 2000's | 49 (51.04) | 29.6817 |
| 2010's | 42 (43.75) | 24.3611 |
| 2020's | 1 (1.04) | 2.80 |
| Authors | Studies |
|---|---|
| Allauze, E; Chabert, J; Chassain, C; De Chazeron, I; Fossati, P; Llorca, PM; Pereira, B; Rotgé, JY; Samalin, L | 1 |
| Chen, F; Chen, G; Huang, H; Jia, Y; Lai, S; Luo, X; Ning, Y; Shan, Y; Shen, S; Wang, Y; Zhang, Y; Zhong, S | 1 |
| Bond, DJ; Honer, WG; Lam, RW; Lang, DJ; MacMillan, EL; Silveira, LE; Su, W; Torres, IJ; Yatham, LN | 1 |
| Clark, E; Huber, RS; Kondo, DG; Prescot, AP; Renshaw, PF; Shi, XF; Yurgelun-Todd, DA | 1 |
| Huang, J; Jia, Y; Lai, S; Liao, X; Sun, Y; Wang, Y; Zhang, S; Zhao, H; Zhong, S | 1 |
| Galińska-Skok, B; Gierus, J; Marcinowicz, P; Mosiolek, A; Szulc, A; Waszkiewicz, N; Wiedlocha, M | 1 |
| Guadagno, E; Li, C; Ramamurthy, J; Trakadis, Y; Wang, A; Wang, C; Zhang, E | 1 |
| Lafer, B; Leite, C; Machado-Vieira, R; Moreno, RA; Nery, FG; Otaduy, MCG; Soeiro-de-Souza, MG | 1 |
| Chen, G; Jia, Y; Lai, S; Liao, X; Liu, T; Wang, Y; Zhong, S | 1 |
| Bustillo, JR; Chavez, L; Gasparovic, C; Jones, T; Lenroot, RK; Lin, D; Qualls, C | 1 |
| Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M | 1 |
| Adler, CM; Blom, TJ; Borgelt, L; Chu, WJ; DelBello, MP; Eliassen, JC; Komoroski, RA; Lee, JH; Rummelhoff, E; Strakowski, SM; Tallman, M; Weber, W; Welge, JA | 1 |
| Chen, X; Du, F; Fan, X; Huynh, P; Lewandowski, KE; Öngür, D | 1 |
| Adler, CM; Chu, WJ; DelBello, MP; Jarvis, KB; Kim, MJ; Lee, JH; Rummelhoff, E; Strakowski, SM; Weber, WA; Welge, J | 1 |
| Adler, CM; Chu, WJ; Delbello, MP; Jarvis, KB; Kim, MJ; Lee, JH; Norris, MM; Strakowski, SM; Weber, W | 1 |
| Anand, A; Dydak, U; Dzemidzic, M; Gunn, AD; Harezlak, J; Karne, HS; Nixon, J; Xu, J | 1 |
| Cowen, PJ; Godlewska, BR; Goodwin, GM; Near, J; Yip, SW | 1 |
| Gigante, AD; Lafer, B; Yatham, LN | 1 |
| Adleman, NE; Bararpour, L; Chang, KD; Howe, M; Jo, B; Kelley, RG; Singh, MK; Spielman, D | 1 |
| Alda, M; Blagdon, R; Calkin, C; Hajek, T; Slaney, C | 1 |
| Adler, CM; Bitter, SM; Chu, WJ; DelBello, MP; Eliassen, JC; Strakowski, SM; Weber, WA | 1 |
| Huang, L; Jia, Y; Ling, X; Liu, S; Wang, Y; Xiang, Q; Zhao, G; Zhong, S | 1 |
| Cohen, BM; Du, F; Goldbach, JR; Lewandowski, KE; Ongür, D; Sehovic, S; Sperry, SH | 1 |
| Algın, O; Atagün, MI; Can, SS; Çayköylü, A; Karakaş-Uğurlu, G; Moore, CM; Öngür, D; Phillips, ML; Şıkoğlu, EM; Ulusoy-Kaymak, S | 1 |
| Abulseoud, OA; Baruth, JM; Choi, DS; Croarkin, PE; Frye, MA; Port, JD; Thomas, MA | 1 |
| Ehrlich, A; Gallinat, J; Pehrs, C; Schubert, F | 1 |
| Bond, DJ; Bücker, J; Kapczinski, F; Kozicky, JM; MacMillan, EL; Muralidharan, K; Rosa, AR; Silveira, LE; Yatham, LN | 1 |
| Aydin, B; Gökmen, N; Olson, D; Renshaw, P; Yildiz, A; Yurt, A | 1 |
| Ghanizadeh, A; Lotfi, M; Razeghian, L; Shafiee, S; Sigaroudi, MO | 1 |
| Guan, JT; Guo, XB; Li, H; Liu, CF; Ou, SM; Shen, ZW; Tan, HZ; Wang, XQ; Wen, CH; Wu, RH; Xu, CT; Zhang, J; Zhang, YN | 1 |
| Chen, K; Guan, J; Li, H; Liang, C; Shen, Z; Wu, R; Xiao, B; Xu, C; Xu, H; Zhang, J; Zhang, Y | 1 |
| Jia, Y; Lai, S; Liao, X; Liu, T; Wang, B; Wang, Y; Zhong, S | 1 |
| Cohen, BM; Jensen, JE; Lundy, M; Öngür, D; Prescot, AP; Renshaw, PF; Stork, C | 1 |
| Backens, M; Bondy, B; Falkai, P; Gruber, O; Möller, HJ; Reith, W; Scherk, H; Schneider-Axmann, T; Usher, J; Wobrock, T; Zill, P | 1 |
| Berlow, YA; Finn, CT; Forester, BP; Moore, CM; Renshaw, PF; Wardrop, M | 1 |
| Adler, CM; Cecil, KM; DelBello, MP; Patel, NC; Strakowski, SM | 1 |
| Brotman, MA; Dickstein, DP; Knopf, L; Leibenluft, E; Onelio, L; Pine, DS; Rich, BA; Towbin, KE; Van Der Veen, JW | 1 |
| Erfurth, A; Michael, N; Pfleiderer, B | 1 |
| Renshaw, PF | 1 |
| Hall, GB; MacQueen, GM; Milne, AM; Senaratne, R | 1 |
| Chen, HH; Hatch, JP; Lafer, B; Monkul, ES; Nery, FG; Nicoletti, MA; Soares, JC; Stanley, JA | 1 |
| Deckersbach, T; Iosifescu, DV; Moore, CM; Nierenberg, AA; Ostacher, MJ; Sachs, GS; Tilley, CA | 1 |
| Cohen, BM; Jensen, JE; Olson, DP; Ongür, D; Prescot, AP; Renshaw, PF; Rouse, ED | 1 |
| Backens, M; Falkai, P; Gruber, O; Kemmer, C; Reith, W; Scherk, H; Schneider-Axmann, T; Usher, J | 2 |
| Adleman, N; Alegria, D; Chang, K; Howe, M; Reiss, A; Singh, M; Spielman, D | 1 |
| Reynolds, GP; Reynolds, LM | 1 |
| Halasz, S; Kliment, E; Sumegi, A | 1 |
| Caetano, SC; Chen, HH; Fonseca, M; Hatch, JP; Hunter, K; Lafer, B; Nicoletti, M; Olvera, RL; Pliszka, SR; Sanches, M; Soares, JC; Stanley, JA | 1 |
| Acquaye, T; Adams, E; Chang, KD; Howe, M; Kelley, R; Libby, A; Reiss, A; Singh, MK; Spielman, D | 1 |
| Backens, M; Ekawardhani, S; Falkai, P; Gruber, O; Hasan, A; Meyer, J; Reith, W; Scherk, H; Schmitt, A; Schneider-Axmann, T; Wobrock, T | 1 |
| Alda, M; Bauer, M; Bohner, G; Cullis, J; Hajek, T; Klingebiel, R; Macqueen, GM; O'Donovan, C; Pfennig, A; Ploch, J; Young, LT | 1 |
| Adler, C; Bryan, H; Chang, K; Chu, WJ; Delbello, M; Eliassen, J; Garrett, A; Howe, M; Kelley, R; Mills, N; Spielman, D; Strakowski, SM | 1 |
| Duffy, S; Hermens, DF; Hickie, IB; Lagopoulos, J; Naismith, SL; Scott, E; Tobias-Webb, J; White, D | 1 |
| Cecil, KM; DelBello, MP; Morey, R; Strakowski, SM | 1 |
| Asghar, SJ; Hanstock, CC; O'Donnell, T; Silverstone, PH; Ulrich, M; Wu, RH | 1 |
| Arolt, V; Erfurth, A; Gössling, M; Heindel, W; Michael, N; Ohrmann, P; Pfleiderer, B | 1 |
| Anzalone, S; Deicken, RF; Feiwell, R; Pegues, MP; Soher, B | 1 |
| Bertolino, A; Callicott, JH; Frye, M; Mattay, VS; Post, R; Rakow, R; Shelton-Repella, J; Weinberger, DR | 1 |
| Adleman, N; Barnea-Goraly, N; Chang, K; Dienes, K; Ketter, T; Reiss, A | 1 |
| Nudmamud, S; Reynolds, GP; Reynolds, LM | 1 |
| Barnett, S; Belin, T; Davanzo, P; McCracken, J; Mintz, J; Santoro, E; Thomas, MA; Venkatraman, TN; Yue, K | 1 |
| Cecil, KM; DelBello, MP; Sellars, MC; Strakowski, SM | 1 |
| Berger, G; Desmond, P; McGorry, PD; Pantelis, C; Phillips, LJ; Velakoulis, D; Wood, SJ; Yung, AR | 1 |
| Altamura, M; Antonucci, N; Bertolino, A; Blasi, G; Brudaglio, F; Nardini, M; Scarabino, T; Sciota, D; Weinberger, DR | 1 |
| Folgierini, M; Frey, BN; Kapczinski, F; Machado-Vieira, R; Nicoletti, M; Soares, JC; Stanley, JA | 1 |
| Brambilla, P; Frank, E; Keshavan, MS; Kupfer, D; Mallinger, AG; Nicoletti, MA; Sassi, RB; Soares, JC; Stanley, JA | 1 |
| Axelson, D; Birmaher, B; Brambilla, P; Keshavan, MS; Nicoletti, MA; Ramos, RT; Ryan, N; Sassi, RB; Soares, JC; Stanley, JA | 1 |
| Adler, CM; Cecil, KM; Daniels, JP; DelBello, MP; Strakowski, SM | 1 |
| Chang, KD; Gallelli, KA; Howe, M; Karchemskiy, A; Reiss, A; Spielman, D; Wagner, CM | 1 |
| Ankerst, DP; Yildiz-Yesiloglu, A | 1 |
| Atmaca, M; Ogur, E; Ozdemir, H; Poyraz, AK; Tezcan, E; Yildirim, H | 1 |
| Amaral, JA; Caetano, SC; Cerri, GG; de Castro, CC; Issler, CK; Lafer, B; Tamada, RS | 1 |
| Frangou, S; Lewis, M; Simmons, A; Wollard, J | 1 |
| Ashworth, F; Bhagwagar, Z; Cowen, PJ; Evans, J; Jezzard, P; Matthews, PM; Sule, A; Wylezinska, M | 1 |
| Binesh, N; Curran, JG; Davanzo, P; Frye, MA; Guze, B; Mintz, J; O'Neill, J; Thomas, MA; Ventura, J; Yue, K | 1 |
| Caetano, SC; Chen, HH; Frey, BN; Hatch, JP; Kapczinski, F; Monkul, ES; Nery, FG; Nicoletti, MA; Ortiz, O; Soares, JC; Stanley, JA | 1 |
| Ivanovski, B; Lagopoulos, J; Malhi, GS; Moss, K; Sachdev, P; Wen, W | 1 |
| Caetano, SC; Chen, HH; Fonseca, M; Hatch, JP; Hunter, K; Nicoletti, M; Olvera, RL; Pliszka, SR; Soares, JC; Stanley, JA | 1 |
| Benito, C; Desco, M; Leal, I; Molina, V; Palomo, T; Rebolledo, R; Reig, S; Sánchez, J; Sanz, J; Sarramea, F | 1 |
| Backens, M; Falkai, P; Gruber, O; Kemmer, C; Kraft, S; Meyer, J; Reith, W; Scherk, H; Schneider-Axmann, T; Usher, J | 1 |
| Marcus, SM; Mrazek, DA; Port, JD; Unal, SS | 1 |
| Bahn, S; Griffin, JL; Holmes, E; Huang, JT; Lan, MJ; Manji, H; McLoughlin, GA; Tsang, TM; Yuan, P | 1 |
| Bajbouj, M; Bubner, M; Colla, M; Heidenreich, JO; Heuser, I; Kronenberg, G; Luborzewski, A; Schubert, F; Seifert, F | 1 |
| Dickstein, DP; Knopf, L; Leibenluft, E; Pine, DS; Towbin, KE; van der Veen, JW | 1 |
| Adler, CM; Cecil, KM; DelBello, MP; Patel, NC; Stanford, KE; Strakowski, SM | 1 |
| Kloos, A; Weller, EB; Weller, RA | 1 |
| Hamakawa, H; Kato, N; Kato, T; Murashita, J | 1 |
| Igarashi, Y; Isoda, H; Ochiai, M; Ohara, K; Suzuki, Y; Takeda, H; Takehara, Y | 1 |
| Castillo, M; Courvoisie, H; Hooper, SR; Kwock, L | 1 |
| Bebchuk, JM; Chen, G; Faulk, MW; Glitz, DA; Hasanat, K; Jolkovsky, L; Koch, S; Manji, HK; Moore, GJ; Seraji-Bozorgzad, N; Wilds, IB | 1 |
| Bebchuk, JM; Chen, G; Manji, HK; Menji, HK; Moore, GJ; Wilds, IB | 1 |
| Belin, T; Davanzo, P; McCracken, J; Oshiro, T; Strober, M; Thomas, MA; Yue, K | 1 |
| Deicken, RF; Eliaz, Y; Feiwell, R; Schuff, N | 1 |
| Bárány, M; Davis, JM; Sharma, R; Venkatasubramanian, PN | 1 |
| Cohen, BM; Gonzalez, RG; Guimaraes, AR; Lafer, B; Miller, C; Renshaw, PF; Sachs, GS; Stoll, AL | 1 |
6 review(s) available for n-acetylaspartic acid and Bipolar Disorder
| Article | Year |
|---|---|
Glutamatergic and N-Acetylaspartate Metabolites in Bipolar Disorder: A Systematic Review and Meta-Analysis of Proton Magnetic Resonance Spectroscopy Studies.
Topics: Aspartic Acid; Bipolar Disorder; Depressive Disorder, Major; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy | 2022 |
Proton magnetic resonance spectroscopy changes after lithium treatment. Systematic review.
Topics: Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Choline; Cross-Sectional Studies; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Lithium Compounds; Proton Magnetic Resonance Spectroscopy; Treatment Outcome | 2018 |
Metabolomics in patients with psychosis: A systematic review.
Topics: 3-Hydroxybutyric Acid; Aspartic Acid; Biomarkers; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutathione; Humans; Kynurenine; Lactic Acid; Linoleic Acid; Male; Metabolome; Metabolomics; Psychotic Disorders; Schizophrenia; Serine; Tryptophan | 2018 |
Applications for magnetic resonance imaging in bipolar disorder.
Topics: Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Brain; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy | 2007 |
Neurochemical alterations of the brain in bipolar disorder and their implications for pathophysiology: a systematic review of the in vivo proton magnetic resonance spectroscopy findings.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Child; Choline; Creatine; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy | 2006 |
Biologic basis of bipolar disorder in children and adolescents.
Topics: Adolescent; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Brain-Derived Neurotrophic Factor; Child; Energy Metabolism; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Humans; Lithium Compounds; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neuropsychological Tests | 2008 |
14 trial(s) available for n-acetylaspartic acid and Bipolar Disorder
| Article | Year |
|---|---|
A Magnetic Resonance Spectroscopy Study of Lovastatin for Treating Bipolar Mood Disorder: A 4-Week Randomized Double-Blind, Placebo- Controlled Clinical Trial.
Topics: Adolescent; Adult; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Choline; Creatine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iran; Lovastatin; Magnetic Resonance Spectroscopy; Male; Middle Aged; Patents as Topic; Time Factors; Young Adult | 2017 |
Brain lithium, N-acetyl aspartate and myo-inositol levels in older adults with bipolar disorder treated with lithium: a lithium-7 and proton magnetic resonance spectroscopy study.
Topics: Aged; Aged, 80 and over; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Cross-Sectional Studies; Female; Humans; Inositol; Linear Models; Lithium Carbonate; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons | 2008 |
Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation.
Topics: Adolescent; Antimanic Agents; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Creatine; Diagnosis, Differential; Double-Blind Method; Female; Glutamine; Humans; Inositol; Lithium Carbonate; Magnetic Resonance Spectroscopy; Male; Mood Disorders; Single-Blind Method | 2009 |
Galantamine-ER for cognitive dysfunction in bipolar disorder and correlation with hippocampal neuronal viability: a proof-of-concept study.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Bipolar Disorder; Brain Mapping; Choline; Cholinesterase Inhibitors; Cognition Disorders; Female; Galantamine; Humans; Magnetic Resonance Spectroscopy; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Protons; Young Adult | 2009 |
Neurometabolite effects of response to quetiapine and placebo in adolescents with bipolar depression.
Topics: Adolescent; Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Child; Dibenzothiazepines; Female; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Imaging; Male; Prefrontal Cortex; Psychiatric Status Rating Scales; Quetiapine Fumarate; Treatment Outcome | 2012 |
Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Cerebral Cortex; Choline; Creatine; Drug Administration Schedule; Female; Humans; Inositol; Lithium; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Valproic Acid | 2003 |
Decreased N-acetylaspartate in children with familial bipolar disorder.
Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Child; Creatine; Family Health; Female; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Reference Values | 2003 |
Proton magnetic resonance spectroscopy of the frontal lobe and cerebellar vermis in children with a mood disorder and a familial risk for bipolar disorders.
Topics: Aspartic Acid; Bipolar Disorder; Brain Chemistry; Cerebellum; Child; Family; Female; Frontal Lobe; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mood Disorders; Phosphocreatine; Protons; Psychiatric Status Rating Scales; Risk; Wechsler Scales | 2003 |
Neurochemical effects of olanzapine in first-hospitalization manic adolescents: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Analysis of Variance; Antipsychotic Agents; Aspartic Acid; Benzodiazepines; Bipolar Disorder; Brain Chemistry; Case-Control Studies; Child; Female; Humans; Magnetic Resonance Spectroscopy; Male; Olanzapine; Prefrontal Cortex; Prospective Studies; Protons; Psychiatric Status Rating Scales; Time Factors | 2006 |
Preliminary in vivo evidence of increased N-acetyl-aspartate following eicosapentanoic acid treatment in patients with bipolar disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Double-Blind Method; Eicosapentaenoic Acid; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neuroprotective Agents; Organ Specificity | 2007 |
Proton magnetic resonance spectroscopy in youth with severe mood dysregulation.
Topics: Antimanic Agents; Arousal; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Brain Mapping; Cerebral Cortex; Chronic Disease; Creatine; Diagnosis, Differential; Dominance, Cerebral; Double-Blind Method; Glutamine; Humans; Image Processing, Computer-Assisted; Inositol; Irritable Mood; Lithium Compounds; Magnetic Resonance Spectroscopy; Mood Disorders; Phosphocreatine | 2008 |
Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects?
Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Brain; Double-Blind Method; Female; Gene Expression Regulation; Genes, bcl-2; Humans; Lithium; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuroprotective Agents; Prospective Studies | 2000 |
Lithium-induced increase in human brain grey matter.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain; Female; Humans; Lithium; Magnetic Resonance Imaging; Male; Middle Aged; Neuroprotective Agents | 2000 |
Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder.
Topics: Adolescent; Area Under Curve; Aspartic Acid; Bipolar Disorder; Child; Creatine; Demography; Drug Administration Schedule; Female; Gyrus Cinguli; Humans; Inositol; Lithium; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome | 2001 |
76 other study(ies) available for n-acetylaspartic acid and Bipolar Disorder
| Article | Year |
|---|---|
Altered biochemical metabolism and its lateralization in the cortico-striato-cerebellar circuit of unmedicated bipolar II depression.
Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Cerebellum; Choline; Creatine; Cross-Sectional Studies; Female; Functional Laterality; Gyrus Cinguli; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; White Matter; Young Adult | 2019 |
Diagnosis and body mass index effects on hippocampal volumes and neurochemistry in bipolar disorder.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Body Mass Index; Brain; Case-Control Studies; Creatine; Dipeptides; Female; Hippocampus; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Obesity; Organ Size; Overweight; Phosphatidylcholines; Phosphocreatine; Young Adult | 2017 |
Relationship of executive functioning deficits to N-acetyl aspartate (NAA) and gamma-aminobutyric acid (GABA) in youth with bipolar disorder.
Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Brain; Case-Control Studies; Executive Function; Female; gamma-Aminobutyric Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Pilot Projects; Proton Magnetic Resonance Spectroscopy; Young Adult | 2018 |
Biochemical abnormalities in basal ganglia and executive dysfunction in acute- and euthymic-episode patients with bipolar disorder: A proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Basal Ganglia; Biomarkers; Bipolar Disorder; Brain; Brain Chemistry; Case-Control Studies; Choline; Corpus Striatum; Creatine; Cyclothymic Disorder; Executive Function; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy | 2018 |
Lithium-associated anterior cingulate neurometabolic profile in euthymic Bipolar I disorder: A
Topics: Adult; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Brain Chemistry; Choline; Cyclothymic Disorder; Female; Gyrus Cinguli; Humans; Inositol; Lithium Compounds; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Treatment Outcome | 2018 |
Associations between executive function impairment and biochemical abnormalities in bipolar disorder with suicidal ideation.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Case-Control Studies; Cerebral Cortex; Choline; Corpus Striatum; Creatine; Executive Function; Female; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Suicidal Ideation; Thalamus; Young Adult | 2018 |
Proton magnetic resonance spectroscopic imaging of gray and white matter in bipolar-I and schizophrenia.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Female; Glutamine; Gray Matter; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia; White Matter; Young Adult | 2019 |
Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression.
Topics: Aged; Aging; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Cerebral Cortex; Creatine; Depression; Energy Metabolism; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Lamotrigine; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Severity of Illness Index; Treatment Outcome | 2019 |
Neurophysiological effects of multiple mood episodes in bipolar disorder.
Topics: Adult; Affect; Amygdala; Aspartic Acid; Attention; Bipolar Disorder; Brain; Brain Mapping; Cerebral Cortex; Corpus Striatum; Emotions; Female; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Prefrontal Cortex; Thalamus | 2019 |
Role of glia in prefrontal white matter abnormalities in first episode psychosis or mania detected by diffusion tensor spectroscopy.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Diffusion Tensor Imaging; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Myelin Sheath; Neuroglia; Neurons; Prefrontal Cortex; Psychotic Disorders; Schizophrenia; White Matter; Young Adult | 2019 |
Neurochemical effects of quetiapine in patients with bipolar mania: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Case-Control Studies; Dibenzothiazepines; Female; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Prospective Studies; Quetiapine Fumarate; Remission Induction; Time Factors; Treatment Outcome; Young Adult | 2013 |
Magnetic resonance spectroscopy imaging of lactate in patients with bipolar disorder.
Topics: Adolescent; Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Young Adult | 2013 |
Neurochemical abnormalities in unmedicated bipolar depression and mania: a 2D 1H MRS investigation.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Creatine; Female; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychiatric Status Rating Scales; Tritium; Young Adult | 2013 |
Cortical glutathione levels in young people with bipolar disorder: a pilot study using magnetic resonance spectroscopy.
Topics: Aspartic Acid; Biomarkers; Bipolar Disorder; Case-Control Studies; Female; Functional Neuroimaging; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Pilot Projects; Prefrontal Cortex; Young Adult | 2014 |
(1)H-MRS of hippocampus in patients after first manic episode.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Glutamic Acid; Glutamine; Hippocampus; Humans; Hydrogen; Inositol; Magnetic Resonance Spectroscopy; Male; Neurons; Prospective Studies; Time Factors; Young Adult | 2014 |
Prospective neurochemical characterization of child offspring of parents with bipolar disorder.
Topics: Adolescent; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Child; Child of Impaired Parents; Creatine; Family Health; Female; Humans; Inositol; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons | 2013 |
Type 2 diabetes mellitus: a potentially modifiable risk factor for neurochemical brain changes in bipolar disorders.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Creatine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychiatric Status Rating Scales; Risk Factors | 2015 |
N-acetyl aspartate levels in adolescents with bipolar and/or cannabis use disorders.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Female; Humans; Male; Marijuana Abuse; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Young Adult | 2014 |
Similarities of biochemical abnormalities between major depressive disorder and bipolar depression: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain; Choline; Creatine; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Young Adult | 2014 |
Myelin vs axon abnormalities in white matter in bipolar disorder.
Topics: Adult; Aspartic Acid; Axons; Bipolar Disorder; Diffusion Tensor Imaging; Female; Humans; Magnetic Resonance Imaging; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Psychotic Disorders; White Matter | 2015 |
Investigation of Heschl's gyrus and planum temporale in patients with schizophrenia and bipolar disorder: a proton magnetic resonance spectroscopy study.
Topics: Adult; Analysis of Variance; Aspartic Acid; Auditory Cortex; Bipolar Disorder; Creatine; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Temporal Lobe; Young Adult | 2015 |
N-acetylaspartate normalization in bipolar depression after lamotrigine treatment.
Topics: Adult; Aged; Aspartic Acid; Biomarkers; Bipolar Disorder; Brain; Dipeptides; Female; Gyrus Cinguli; Humans; Lamotrigine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values; Triazines | 2015 |
Alterations of cerebral glutamate in the euthymic state of patients with bipolar disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Female; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy | 2015 |
Hippocampal neurochemical markers in bipolar disorder patients following the first-manic episode: A prospective 12-month proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Male; Prospective Studies; Proton Magnetic Resonance Spectroscopy; Young Adult | 2017 |
Trait-related alterations of N-acetylaspartate in euthymic bipolar patients: A longitudinal proton magnetic resonance spectroscopy study.
Topics: Adult; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Choline; Cyclothymic Disorder; Female; Frontal Lobe; Gyrus Cinguli; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Phosphocreatine; Prefrontal Cortex | 2016 |
Main Effects of Diagnoses, Brain Regions, and their Interaction Effects for Cerebral Metabolites in Bipolar and Unipolar Depressive Disorders.
Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Depressive Disorder, Major; Glutamine; Gray Matter; Humans; Inositol; Organ Specificity | 2016 |
Differential neurometabolite alterations in brains of medication-free individuals with bipolar disorder and those with unipolar depression: a two-dimensional proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Depressive Disorder; Female; Gyrus Cinguli; Humans; Inositol; Male; Middle Aged; Parietal Lobe; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Statistics as Topic | 2016 |
A comparison of neurometabolites between remitted bipolar disorder and depressed bipolar disorder: A proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Female; Humans; Male; Middle Aged; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; White Matter | 2017 |
Abnormal glutamatergic neurotransmission and neuronal-glial interactions in acute mania.
Topics: Acute Disease; Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Cerebral Cortex; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Neuroglia; Neurons; Neurotransmitter Agents; Occipital Lobe; Parietal Lobe; Pilot Projects; Reference Values; Schizophrenia; Synaptic Transmission; Young Adult | 2008 |
SNAP-25 genotype influences NAA/Cho in left hippocampus.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; DNA; Female; Genotype; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Obsessive-Compulsive Disorder; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia; Synaptosomal-Associated Protein 25 | 2008 |
Neurochemical alterations in adolescent bipolar depression: a proton magnetic resonance spectroscopy pilot study of the prefrontal cortex.
Topics: Adolescent; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Child; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Pilot Projects; Prefrontal Cortex | 2008 |
Elevated metabolites within dorsolateral prefrontal cortex in rapid cycling bipolar disorder.
Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Brain; Choline; Creatine; Female; Functional Laterality; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex | 2009 |
Increased choline-containing compounds in the orbitofrontal cortex and hippocampus in euthymic patients with bipolar disorder: a proton magnetic resonance spectroscopy study.
Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Female; Frontal Lobe; Functional Laterality; Glutamic Acid; Glutamine; Glycerylphosphorylcholine; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphorylcholine; Psychiatric Status Rating Scales; Severity of Illness Index | 2009 |
Bipolar disorder comorbid with alcoholism: a 1H magnetic resonance spectroscopy study.
Topics: Adult; Age Factors; Alcoholism; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Brain; Comorbidity; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Sex Factors | 2010 |
T2 relaxation time abnormalities in bipolar disorder and schizophrenia.
Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Brain; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Tissue Distribution | 2010 |
Cortical neurochemistry in euthymic patients with bipolar I disorder.
Topics: Adult; Affect; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dominance, Cerebral; Female; Gyrus Cinguli; Humans; Inositol; Lithium Carbonate; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Middle Aged; Prefrontal Cortex; Reference Values; Sex Factors; Young Adult | 2009 |
Brain glutamatergic characteristics of pediatric offspring of parents with bipolar disorder.
Topics: Adolescent; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Brain Mapping; Child; Child of Impaired Parents; Cohort Studies; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Pediatrics; Protons; Psychiatric Status Rating Scales | 2010 |
Differential regional N-acetylaspartate deficits in postmortem brain in schizophrenia, bipolar disorder and major depressive disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Depressive Disorder, Major; Dipeptides; Female; Humans; Male; Middle Aged; Schizophrenia | 2011 |
[Application of lamotrigine in bipolar disorder--3T MR spectroscopy follow up (part 1)].
Topics: Antimanic Agents; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Excitatory Amino Acid Antagonists; Female; Hippocampus; Humans; Lamotrigine; Magnetic Resonance Spectroscopy; Treatment Outcome; Triazines; Young Adult | 2010 |
Lower N-acetyl-aspartate levels in prefrontal cortices in pediatric bipolar disorder: a ¹H magnetic resonance spectroscopy study.
Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Child; Diagnostic and Statistical Manual of Mental Disorders; Female; Glycerylphosphorylcholine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Phosphorylcholine; Prefrontal Cortex; Protons | 2011 |
Neurochemical deficits in the cerebellar vermis in child offspring of parents with bipolar disorder.
Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Cerebellum; Child; Choline; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Protons; Psychiatric Status Rating Scales | 2011 |
Association of the brain-derived neurotrophic factor val66met polymorphism with magnetic resonance spectroscopic markers in the human hippocampus: in vivo evidence for effects on the glutamate system.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Creatine; Female; Genetic Association Studies; Genotype; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memory; Methionine; Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Protons; Schizophrenia; Valine; Verbal Learning | 2012 |
Large positive effect of lithium on prefrontal cortex N-acetylaspartate in patients with bipolar disorder: 2-centre study.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Cost of Illness; Female; Humans; Image Processing, Computer-Assisted; Lithium Compounds; Magnetic Resonance Imaging; Male; Middle Aged; Neuroprotective Agents; Prefrontal Cortex; Psychiatric Status Rating Scales | 2012 |
In vivo glutathione levels in young persons with bipolar disorder: a magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Female; Glutathione; Humans; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Young Adult | 2013 |
Frontal lobe differences in bipolar disorder as determined by proton MR spectroscopy.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Choline; Female; Frontal Lobe; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Multivariate Analysis; Protons | 2002 |
Acute mania is accompanied by elevated glutamate/glutamine levels within the left dorsolateral prefrontal cortex.
Topics: Acute Disease; Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Receptors, Glutamate | 2003 |
Lower concentration of hippocampal N-acetylaspartate in familial bipolar I disorder.
Topics: Adult; Ambulatory Care; Aspartic Acid; Axons; Bipolar Disorder; Choline; Creatine; Family; Functional Laterality; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons | 2003 |
Neuronal pathology in the hippocampal area of patients with bipolar disorder: a study with proton magnetic resonance spectroscopic imaging.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Female; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Prefrontal Cortex; Protons | 2003 |
N-acetylaspartate and N-Acetylaspartylglutamate deficits in superior temporal cortex in schizophrenia and bipolar disorder: a postmortem study.
Topics: Aspartic Acid; Autopsy; Biomarkers; Bipolar Disorder; Case-Control Studies; Chromatography, High Pressure Liquid; Depressive Disorder; Dipeptides; Frontal Lobe; Humans; Schizophrenia; Temporal Lobe | 2003 |
Proton magnetic resonance spectroscopy of bipolar disorder versus intermittent explosive disorder in children and adolescents.
Topics: Adolescent; Age Factors; Aspartic Acid; Bipolar Disorder; Child; Choline; Creatine; Diagnosis, Differential; Disruptive, Impulse Control, and Conduct Disorders; Female; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Phosphocreatine | 2003 |
Proton magnetic resonance spectroscopy in first episode psychosis and ultra high-risk individuals.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain Mapping; Choline; Creatine; Depressive Disorder, Major; Dominance, Cerebral; Energy Metabolism; Female; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Net; Prefrontal Cortex; Psychotic Disorders; Reference Values; Risk; Schizophrenia; Schizotypal Personality Disorder; Temporal Lobe | 2003 |
Hippocampal neurochemical pathology in patients at first episode of affective psychosis: a proton magnetic resonance spectroscopic imaging study.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Cerebral Cortex; Choline; Creatine; Depressive Disorder, Major; Dominance, Cerebral; Female; Gyrus Cinguli; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurons; Phosphocreatine; Psychiatric Status Rating Scales; Putamen; Reference Values; Thalamus | 2004 |
A proton magnetic resonance spectroscopy investigation of the dorsolateral prefrontal cortex in acute mania.
Topics: Acute Disease; Adult; Antimanic Agents; Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Choline; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Inositol; Magnetic Resonance Imaging; Male; Middle Aged; Patient Selection; Phosphocreatine; Prefrontal Cortex | 2005 |
1H magnetic resonance spectroscopy investigation of the dorsolateral prefrontal cortex in bipolar disorder patients.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Creatine; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Prefrontal Cortex; Radiography | 2005 |
Reduced NAA levels in the dorsolateral prefrontal cortex of young bipolar patients.
Topics: Adolescent; Adult; Age Factors; Aspartic Acid; Bipolar Disorder; Child; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Nerve Degeneration; Phosphocreatine; Prefrontal Cortex; Recurrence | 2005 |
N-acetylaspartate levels in bipolar offspring with and at high-risk for bipolar disorder.
Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Child; Cohort Studies; Creatine; Demography; Family Health; Female; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons; Risk Factors | 2005 |
Hippocampal 1H MRS in first-episode bipolar I patients.
Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Female; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Statistics as Topic | 2006 |
A 1HMRS study of the anterior cingulate gyrus in euthymic bipolar patients.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Female; Gyrus Cinguli; Humans; Lithium; Magnetic Resonance Spectroscopy; Male; Middle Aged | 2006 |
Reduction in occipital cortex gamma-aminobutyric acid concentrations in medication-free recovered unipolar depressed and bipolar subjects.
Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Brain Mapping; Depressive Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Middle Aged; Occipital Lobe; Reference Values | 2007 |
Reduced concentrations of N-acetylaspartate (NAA) and the NAA-creatine ratio in the basal ganglia in bipolar disorder: a study using 3-Tesla proton magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Creatine; Female; Hospitalization; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Parietal Lobe; Protons | 2007 |
Abnormal cellular energy and phospholipid metabolism in the left dorsolateral prefrontal cortex of medication-free individuals with bipolar disorder: an in vivo 1H MRS study.
Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Creatine; Energy Metabolism; Female; Functional Laterality; Humans; Magnetic Resonance Spectroscopy; Male; Mental Status Schedule; Middle Aged; Phosphocreatine; Phospholipids; Prefrontal Cortex; Protons; Severity of Illness Index | 2007 |
Measuring mania metabolites: a longitudinal proton spectroscopy study of hypomania.
Topics: Adult; Affect; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Brain Mapping; Choline; Energy Metabolism; Female; Frontal Lobe; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Inositol; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychiatric Status Rating Scales; Reference Values | 2007 |
Low levels of N-acetyl aspartate in the left dorsolateral prefrontal cortex of pediatric bipolar patients.
Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Child; Creatine; Female; Glycerylphosphorylcholine; Humans; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Phosphorylcholine; Prefrontal Cortex; Puberty | 2007 |
Dorsolateral prefrontal N-acetyl-aspartate concentration in male patients with chronic schizophrenia and with chronic bipolar disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Cerebrospinal Fluid; Choline; Chronic Disease; Creatine; Fourier Analysis; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Prefrontal Cortex; Reference Values; Schizophrenia | 2007 |
Dopamine transporter genotype influences N-acetyl-aspartate in the left putamen.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dominance, Cerebral; Dopamine Plasma Membrane Transport Proteins; Female; Frontal Lobe; Genotype; Gyrus Cinguli; Homozygote; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Minisatellite Repeats; Neurons; Obsessive-Compulsive Disorder; Prefrontal Cortex; Putamen; Reference Values; Young Adult | 2009 |
Metabolic alterations in medication-free patients with bipolar disorder: a 3T CSF-corrected magnetic resonance spectroscopic imaging study.
Topics: Adolescent; Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Brain; Case-Control Studies; Caudate Nucleus; Corpus Striatum; Creatine; Cross-Sectional Studies; Dominance, Cerebral; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values | 2008 |
Neurochemical pathology in hippocampus in euthymic patients with bipolar I disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dysthymic Disorder; Female; Hippocampus; Humans; Inositol; Male; Putamen; Thalamus | 2008 |
Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder.
Topics: Adult; Analysis of Variance; Animals; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Creatine; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Metabolomics; Middle Aged; Prefrontal Cortex; Rats; Rats, Inbred WKY; Reference Values | 2009 |
Glutamate as a spectroscopic marker of hippocampal structural plasticity is elevated in long-term euthymic bipolar patients on chronic lithium therapy and correlates inversely with diurnal cortisol.
Topics: Adult; Aged; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Circadian Rhythm; Creatine; Female; Glutamic Acid; Hippocampus; Humans; Hydrocortisone; Linear Models; Lithium Chloride; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuronal Plasticity; Saliva | 2009 |
Temporal change in N-acetyl-aspartate concentrations in adolescents with bipolar depression treated with lithium.
Topics: Adolescent; Affect; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Child; Dominance, Cerebral; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Lithium Compounds; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Software | 2008 |
Quantitative proton magnetic resonance spectroscopy of the basal ganglia in patients with affective disorders.
Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Choline; Creatine; Depressive Disorder; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mood Disorders; Phosphocreatine | 1998 |
Proton magnetic resonance spectroscopy of the lenticular nuclei in bipolar I affective disorder.
Topics: Adult; Age Factors; Aspartic Acid; Bipolar Disorder; Brain Mapping; Cell Survival; Choline; Corpus Striatum; Creatine; Dominance, Cerebral; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Reference Values | 1998 |
Proton MR spectroscopy in children with bipolar affective disorder: preliminary observations.
Topics: Aspartic Acid; Basal Ganglia; Bipolar Disorder; Child; Choline; Creatine; Energy Metabolism; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Lipid Metabolism; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Reference Values; Temporal Lobe | 2000 |
Increased thalamic N-acetylaspartate in male patients with familial bipolar I disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Humans; Hypertrophy; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuroglia; Thalamus | 2001 |
Proton magnetic resonance spectroscopy of the brain in schizophrenic and affective patients.
Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Choline; Creatine; Depressive Disorder; Energy Metabolism; Female; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Phosphates; Phosphocreatine; Protons; Schizophrenia; Schizophrenic Psychology | 1992 |
The human brain resonance of choline-containing compounds is similar in patients receiving lithium treatment and controls: an in vivo proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Choline; Corpus Callosum; Humans; Lithium Carbonate; Magnetic Resonance Spectroscopy; Male; Parietal Lobe; Phosphocreatine | 1992 |